LOCUS       NZ_CP076538            21614 bp    DNA     circular CON 16-DEC-2024
DEFINITION  Amycolatopsis aidingensis strain YIM 96748 chromosome, complete
            genome.
ACCESSION   NZ_CP076538
VERSION     NZ_CP076538.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis aidingensis
  ORGANISM  Amycolatopsis aidingensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     YIM 96748 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2021) Yunnan University, Yunnan Institute of
            Microbiology, 121 Street, Yunnan 650000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdevono v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018885265.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:59:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,118
            CDSs (total)                      :: 7,060
            Genes (coding)                    :: 6,941
            CDSs (with protein)               :: 6,941
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 44 of 119
            Pseudo Genes (incomplete)         :: 87 of 119
            Pseudo Genes (internal stop)      :: 2 of 119
            Pseudo Genes (multiple problems)  :: 13 of 119
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:56:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2012631
            Orig. end                         :: 2034245
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21614
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21614
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21614
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11614](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11614)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    225..238
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     repeat_region   244..700
                     /inference="COORDINATES: alignment:CRISPRCasFinder:4.3.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2012875..2012903
                     /rpt_unit_seq="gtgctccccgcacgcgcggggatggtccc"
     gene            981..1640
                     /locus_tag="KOI47_RS09565"
     CDS             981..1640
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153119.1"
                     /locus_tag="KOI47_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SH3 domain-containing protein"
                     /protein_id="WP_216215631.1"
                     /transl_table=11
                     /translation="MACSQFRRIAGRTVTVFAAVTGLVLAGVVPAGASVDGTVRTAGGP
                     LNVRRAPTTTSTVVGSVDNGTKVTIDCQTHGTRISGELGTTTLWDYVPSLGGYVSDAYM
                     YTGSDGQIAPSCGVGTGSAECSTGGCAGEGLFRSEDATFVVWDRSPDGKSAVVQYWLAG
                     GVGPLVVRHSGGSGTSTEQAIDLQPDDWVYYKVCVRDYSGGTGFESCSNGITDYAA"
     gene            1661..3217
                     /locus_tag="KOI47_RS09570"
     CDS             1661..3217
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072054.1"
                     /locus_tag="KOI47_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alkaline phosphatase"
                     /protein_id="WP_216215632.1"
                     /transl_table=11
                     /translation="MSAVNRRLVLLGGLASAAGAMALPSGVPSWAGSRTSAAAPPIRDP
                     FQLGVASGDPLPDSVVLWTRLAPAPLNPDGLGGMPDASYDVDWEIATDENFGSVVQRGT
                     VAAARAQGHSVHVEPRGLDAGREYFYRFRAGGHISPAGRTRTAPAAGATVNQLKYCFTS
                     CQHWEEGWYHAHRGMAEDNPDLVLFLGDYIYEKPSGRGSAEKVRGLAVPEETTTLALYR
                     ARHAQHKTDYDLQAAHAAAPWLVVFDDHEVVNNWNSTTDRASNARKAAAFQAFYENNPI
                     RSSAKPNGASIQLYRQFLWGNLARFHMLDTRQYRSKQAGRHDCSVMRDRSRTLTGSAQE
                     QWLLNAFESHPATWDFLGQQVFFAQRDTDGRSATCDRSSDAWDGYLGSRDRITQGWIDR
                     GVPNPIVLTGDVHRHWAADLRKDYFDHSDPIVGSELVSTSASTSSAGVTPPSDTWYSNN
                     PHIRYYKGERGYVRVTATPEQLRADFRVVSDALERDPAKVTIGTDASFEVRAGERGLHK
                     V"
     misc_feature    complement(3268..3286)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            3326..3850
                     /locus_tag="KOI47_RS09575"
     CDS             3326..3850
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240634.1"
                     /locus_tag="KOI47_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_216215633.1"
                     /transl_table=11
                     /translation="MSVAHVLLGLLEPGPRHGYDLKRAYDVQFGHDKPLAYGQVYSTLS
                     RLLRNGMIEVSGVEHGDGPERKRYTITDAGVTDVEKWLTAPESPEPYLQNTLYTKVVLA
                     LLSGRSAAAVLDTQRAEHLKLMRTLTRRKNEGDLADRLICDHALFHLEADLRWLELTTA
                     RLDELAQAVRA"
     gene            3847..4569
                     /locus_tag="KOI47_RS09580"
     CDS             3847..4569
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684787.1"
                     /locus_tag="KOI47_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_216215634.1"
                     /transl_table=11
                     /translation="MNPGNSAENTAHTAGSEPVLVAEGIAKAFGQTVALRDATASVGAG
                     EMLAVMGPSGSGKSTLLHCLAGIVPPDSGEIRYQGRDLAALSDRERSALRRSEFGFVFQ
                     FGQLVPELTCLENVALPLRLSGMRRKRAETEARYWLTRLEVEEVAAKRPGDVSGGQGQR
                     VAVARALVTGPRVVFADEPTGALDSLNGEKVLHLLTDAARHTGAAVVLVTHEPRVAAYS
                     DREIVVRDGSVSDRELVG"
     gene            4566..6887
                     /locus_tag="KOI47_RS09585"
     CDS             4566..6887
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077145.1"
                     /locus_tag="KOI47_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_216215635.1"
                     /transl_table=11
                     /translation="MSGLKDFALGLRLAVGGGRISGAALLRLSMTAVGIALAVALLLLA
                     TSIGHLTGERRDRVAATQEITDTRPGVDPLRWHSTGKQVGEDYLELLAVAPTGPAAPVP
                     PGLERLPGPGELVVSPEVANRLATPEGDSIRARLPGTVVGQIGKPGLVDPGDLLVYQGF
                     TPAELEEQLGEATPEEVYGFGVPSDAGEMSATTLLLVAPAAAVLLMPLLIFVTTASRMG
                     AAQRDRRLAGLRLLGLDAKQVRRVAAAESLLGAMLGLVAGIGLFLALRPLIGSLELFGM
                     RFFAADFVPNPVLGALVLLLVPALAVGAALFGLRRTIVEPLGVVRQGRTTRRRMWWRWL
                     LTGAGAVTLACTLFIPLSSRGSLAAFLLVGGTVLLLFGIVSVLPWAVEKLVRALRGGSP
                     SWQFAVRRLQLDSGTPSRVVSGLVVVLAGTILIQGLLASVGSAEEIPARPLAQNPGPVR
                     VQVEQDDLPEVRTRLAEVAEVTGTRLIRQATVGESPGQGSAATVEIGDCAALAARATLG
                     PCSDGDVFYVPYPEQYDYRPGPPPRNVMFLGQDERGSAAEWSIPGPIREIAPRHAEKYL
                     GGTVLATPGALGDTPMPADARLMLYVGGTGTIPELADQVALALRPLGLRTDISYARSTS
                     FSQVENERIANFRAALLTASLFVLVVAALSLLMLAVEQITERRRALAALSAAGVPLSVL
                     GRASLWQTAIPVGVGVVLAVAAGIGLTLPSLRLADVPIAIDATAILGLSAAAVLAVLLV
                     TVLTLPLLRQVTKLDALRAE"
     gene            7041..7859
                     /locus_tag="KOI47_RS09590"
     CDS             7041..7859
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005443974.1"
                     /locus_tag="KOI47_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_216215636.1"
                     /transl_table=11
                     /translation="MAVPAAGALSENGAGQATIARICDYWLGGSQHTEADRRAGDHILL
                     CAPHLAYVLRTQQAQVDRMVRYLTAAGIRQFLDLGSRLPTAGNVHEIARECIPESRVLY
                     VDHDTEVARDGARLLAGDERAGFLHADPLDPVQVLGSSALRGLLDLREPTAVLMTNLLQ
                     HVPDSADPAALVGRYVGAVSPGSYLGISHFGSDEQLVTGLGMFNRMFGTPPPVTLREPE
                     QIRPFFAGLELVEPGIVPLPLWRPTEVALDDRNPEEFRVYVGLGHKRLPG"
     gene            complement(7856..8770)
                     /locus_tag="KOI47_RS09595"
     CDS             complement(7856..8770)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420680.1"
                     /locus_tag="KOI47_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_232376645.1"
                     /transl_table=11
                     /translation="MAESRATRRVAVHEVVAVHRLGHGLWLSYLCYASWGAAFAGAALP
                     GPALPAIGANLLLTTAGMAVNTVADTGTDARHRHKFRQAGVARAVGRARIRRWATAEAV
                     AGLALALAAAVWSGRWPVAMAGVLILGLHLLYNLEPVRLKRRGFLGPAAFGCATMALPV
                     VLSFAAAGARFDPAMGLVVFGLGVLGTGRTALFSVTDRAADAATGFRTPAVRYGTGRAL
                     ALSCALSGAGVALLGIGLWWWHGALLALAGMLGTGAFLGGTLALLRDPTAVRRMIRYAL
                     TPAVLGNLLLLAAALAVPGGTGA"
     gene            complement(8763..10004)
                     /locus_tag="KOI47_RS09600"
     CDS             complement(8763..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452086.1"
                     /locus_tag="KOI47_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_216215637.1"
                     /sec_met_domain="p450 (E-value: 4.1e-47, bitscore: 159.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAELQLAVRPLAYLNAIADSPDGMVELRPGTAPRLLVWHPEVL
                     EEIFRSDRRLAHPGSRSLTPLLGPGSLLWADGERHAAYRRVLGPALRGRALTGHREIIA
                     GHLRAAIDELRPGTVVPLAAWTRKLALRIIGRIVLGAPEPGMLAEFGGWLRRAFGSRTR
                     GLAYRFLGVRLPRSGPDLDRALVRAARAGHDDGQATLAALLLSGDGPIGELGEAELRDQ
                     IVSLLFAGHETTATAMTWTLLWLDRDRRLREAVLAELADADADGSDATRTPLLQAVIQE
                     VLRLTPSTAIGENRMLTEETELGGRRFPAGTVCTLSIYLAHRRPEAFAAPRRFDPGRFL
                     GTRPPRHYFPFGGGTRRCLGSGLAQLEIRMLVAELLRRRHWHCVNPGAGRVRIRGNLLT
                     PDPALRMRVTGDRG"
     gene            complement(10001..11614)
                     /locus_tag="KOI47_RS09605"
     CDS             complement(10001..11614)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005454083.1"
                     /locus_tag="KOI47_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_216215638.1"
                     /sec_met_domain="T2TS (E-value: 5e-87, bitscore: 291.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHESWTAQAHRAVTELLAESAADAYGSFSPSVYETARLISLAP
                     TLPAHKDRIGFVLDRQRPDGTWGGPDDYRFVPTLSAIEALLRVLHRREMPGAGERIAAA
                     TARGLDAMDRAARTGAGPSLPDTVAVELIVPGLIIDINRLLEAPAPAELAEWHGHRLPI
                     PAGARPELLGSLREAVRHGRELPGKLLHSLEIIGPPARGATFAGPTEHGVGCSPAATAA
                     WLGTETAVPGGSPCLAYLEAVRGPEGAVPVAAPLALFERSWILSTLASSGLGLPAHGEP
                     ADAVDAALTESGAAGGTGLPPDADDTATALYALALLGRPREPDSLWKYRTGRHFHCFPA
                     ERTPSTTANAHVLQAFGAWLATHPASPARYADALTGLVAWLCEQQRPDGSWADKWHASP
                     YYATACCATALADYGGAAARSAVRGAVDWVLLSQHDDGTWGRWGGTYEETAYAVKILLN
                     TRVPRTGDAIARAAAHGALSLLHWDQDAEHPPLWHDKDLYTPLRIVRAEALAALHLAHT
                     DPAVSALLAEPVTGQEFEPS"
     gene            complement(11850..12770)
                     /locus_tag="KOI47_RS09610"
     CDS             complement(11850..12770)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (15-230). E-value: 6.3e-41.
                     Score: 132.4. Matches aSDomain:
                     nrpspksdomains_KOI47_RS09610_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_132123276.1"
                     /locus_tag="KOI47_RS09610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_216215639.1"
                     /sec_met_domain="ADH_N (E-value: 4.4e-06, bitscore: 25.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.4e-09, bitscore:
                     34.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKAARFSRYGGPEVLTVEEVPLPEPGRGQVRVAVAAAGVNAIDW
                     KIRSGFFAGSDAPDEPQGTGFDLAGTVDAVGEGVRSLRPGTAVFGKAATGAVATHALAD
                     ADGLVAKPDWLSFPLAAGLPVVAETAYRTLRDLGLRAGHTLLIHAVSGGVGLVAAQLAL
                     SRGATVIGTASRGHHDFLTELGVRPVEYGEGLLERVRGVTDSVDLVLDAAGRDVLGLSV
                     ELTGDPDRVLTIADGNAGAHGVRFSGGGPDAAPLPEVFAEVLPMLESGALRLPIQQTFP
                     LERIADAHRLSEDGHGRGKIVIEVG"
     aSDomain        complement(12081..12725)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS09610_PKS_ER.1"
                     /evalue="6.30E-41"
                     /label="KOI47_RS09610_PKS_ER.1"
                     /locus_tag="KOI47_RS09610"
                     /protein_end="230"
                     /protein_start="15"
                     /score="132.4"
                     /tool="antismash"
                     /translation="LTVEEVPLPEPGRGQVRVAVAAAGVNAIDWKIRSGFFAGSDAPDE
                     PQGTGFDLAGTVDAVGEGVRSLRPGTAVFGKAATGAVATHALADADGLVAKPDWLSFPL
                     AAGLPVVAETAYRTLRDLGLRAGHTLLIHAVSGGVGLVAAQLALSRGATVIGTASRGHH
                     DFLTELGVRPVEYGEGLLERVRGVTDSVDLVLDAAGRDVLGLSVELTGDPDR"
     CDS_motif       complement(12285..12347)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KOI47_RS09610_0001"
                     /evalue="2.70E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="KOI47_RS09610"
                     /protein_end="162"
                     /protein_start="141"
                     /score="16.7"
                     /tool="antismash"
                     /translation="GHTLLIHAVSGGVGLVAAQLA"
     gene            complement(12801..13763)
                     /locus_tag="KOI47_RS09615"
     CDS             complement(12801..13763)
                     /NRPS_PKS="Domain: PKS_ER (14-317). E-value: 1.9e-34.
                     Score: 111.1. Matches aSDomain:
                     nrpspksdomains_KOI47_RS09615_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009951430.1"
                     /locus_tag="KOI47_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_216215640.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1e-21, bitscore:
                     76.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVQVTRFGGPEVLEVRQVPDVRAGQGQVVVRVAVADVLFLDTQ
                     LRSGWGGEHFPLHPPYVPGGGVAGTVLSVGPDVPEDLVGRRVVTMTDGGGYAERVLADA
                     AGLVDVPDELSLPDAAALLQTGPAALSLVEAAALEPGEWVLVTAAGGGLGLLLVQLARA
                     AGARVVAAAGGARKLDAAGQLGAELTVDYTEPDWTARVSAATGGPRVVFDGVGGDLGAA
                     AFSLAARGGRMFAYGVPSGGFAEIDAGEAQRREITVTGIEQVQFAPADGTRLAGQVLRA
                     AAQGRVTPVIGRTFPLERAAEAHAAIESREVVGRTLLLA"
     aSDomain        complement(12813..13721)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS09615_PKS_ER.1"
                     /evalue="1.90E-34"
                     /label="KOI47_RS09615_PKS_ER.1"
                     /locus_tag="KOI47_RS09615"
                     /protein_end="317"
                     /protein_start="14"
                     /score="111.1"
                     /tool="antismash"
                     /translation="LEVRQVPDVRAGQGQVVVRVAVADVLFLDTQLRSGWGGEHFPLHP
                     PYVPGGGVAGTVLSVGPDVPEDLVGRRVVTMTDGGGYAERVLADAAGLVDVPDELSLPD
                     AAALLQTGPAALSLVEAAALEPGEWVLVTAAGGGLGLLLVQLARAAGARVVAAAGGARK
                     LDAAGQLGAELTVDYTEPDWTARVSAATGGPRVVFDGVGGDLGAAAFSLAARGGRMFAY
                     GVPSGGFAEIDAGEAQRREITVTGIEQVQFAPADGTRLAGQVLRAAAQGRVTPVIGRTF
                     PLERAAEAHAAIESREVVGRTL"
     CDS_motif       complement(13083..13160)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KOI47_RS09615_0002"
                     /evalue="2.60E+00"
                     /label="PKSI-ER_m5"
                     /locus_tag="KOI47_RS09615"
                     /protein_end="227"
                     /protein_start="201"
                     /score="1.2"
                     /tool="antismash"
                     /translation="SAATGGPRVVFDGVGGDLGAAAFSLA"
     CDS_motif       complement(13281..13343)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KOI47_RS09615_0001"
                     /evalue="2.80E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="KOI47_RS09615"
                     /protein_end="161"
                     /protein_start="140"
                     /score="13.6"
                     /tool="antismash"
                     /translation="GEWVLVTAAGGGLGLLLVQLA"
     gene            complement(13869..14519)
                     /locus_tag="KOI47_RS09620"
     CDS             complement(13869..14519)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.5"
                     /locus_tag="KOI47_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_216215641.1"
                     /sec_met_domain="Abi (E-value: 9.1e-09, bitscore: 34.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAAPPIRLYLAVEYTVLFFGLVVLYTLLFQGTSPIPVLLVLGAA
                     VVMYLLRSPAFDRSALWRPDALPGQLRSIGLLWGVTAVGAGAVVAIARPELLFTLPREE
                     PLTWALVMVLYPLASVYPQELIFRAFLFQRYAPVFGEGHGMVGASAAAFGFVHLPFGNW
                     IAIVLSLAGGWIFASRYRRTRSLFTVSFEHALYGMLIFTIGLGLYFYHGAVPG"
     gene            complement(14577..14972)
                     /locus_tag="KOI47_RS09625"
     CDS             complement(14577..14972)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668217.1"
                     /locus_tag="KOI47_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RidA family protein"
                     /protein_id="WP_216215642.1"
                     /transl_table=11
                     /translation="MTHTIVNPAELHDPVPFGYSHLTEVPAGRLVFVAGQYGSGADGQV
                     VSADFATQVRQAVANLGTALGAVGLGYRNVVRLGTYVVGHDAAKLETITGVLGEIWGER
                     PPAQTLIGVAALALPEMAFEIDAVATG"
     gene            complement(14969..15451)
                     /locus_tag="KOI47_RS09630"
     CDS             complement(14969..15451)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004560538.1"
                     /locus_tag="KOI47_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_216215643.1"
                     /transl_table=11
                     /translation="MTNNGMQRVNITKAAPKAFKALIGFDAAAREGLDPALVELVQIRA
                     SQLNHCAYCLHMHTSDARKAGADEQRLHMVAVWREATGFFTEEEQAALDLTEAVTKVSV
                     DGVPDEVYRRAAASFDETRLATLITMICTINTWNRIAISTAKVPGTDERPGSGSAA"
     gene            15499..16908
                     /locus_tag="KOI47_RS09635"
     CDS             15499..16908
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (123-394). E-value:
                     6.8e-14. Score: 43.7. Matches aSDomain:
                     nrpspksdomains_KOI47_RS09635_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229297.1"
                     /locus_tag="KOI47_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_216215644.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.2e-12, bitscore:
                     43.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDSWVNWAERVGRDLHLELPGKGGRRAALIRALREAIRTGRLAP
                     GTRLPPYRSLAADLGLARNTVADAYAELVAEGWLTARQGSGTAVAIRAEPLPAGRSRAR
                     AGPRLTHDLRQGQPDAASFPRTDWLASARRALLAAPTEAFGPGDPRGRPELRRALAGYL
                     ARVRGVRTEPERIVICAGFAHALRLLFGGGVLGGPLAVESYGLDFHRSLLAEAGVRTIP
                     LTLDEHGAAVAELTGLREVRTVLLTPAHQFPTGGPLHPQRRSAVVEWAGARDGLLLEDD
                     YDGEFRYDRQPVGAVQGLDPDRVVYLGSVSKSLSPAVRLGWMVLPEHLVDTVLRVKGER
                     EGWVGVADQLTLADLIESGAYDRHVRRMRQRYRRRRDQLVDLLALRAPHIVPTGIAAGL
                     HAVLRLRPGTERSILDAAGWQGLAVDGLAPFRHPEATMPAAEGLVVGYATPPEHGYPAA
                     IEALCGVLPPP"
     aSDomain        15868..16680
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS09635_Aminotran_1_2.1"
                     /evalue="6.80E-14"
                     /label="KOI47_RS09635_Aminotran_1_2.1"
                     /locus_tag="KOI47_RS09635"
                     /protein_end="394"
                     /protein_start="123"
                     /score="43.7"
                     /tool="antismash"
                     /translation="PRTDWLASARRALLAAPTEAFGPGDPRGRPELRRALAGYLARVRG
                     VRTEPERIVICAGFAHALRLLFGGGVLGGPLAVESYGLDFHRSLLAEAGVRTIPLTLDE
                     HGAAVAELTGLREVRTVLLTPAHQFPTGGPLHPQRRSAVVEWAGARDGLLLEDDYDGEF
                     RYDRQPVGAVQGLDPDRVVYLGSVSKSLSPAVRLGWMVLPEHLVDTVLRVKGEREGWVG
                     VADQLTLADLIESGAYDRHVRRMRQRYRRRRDQLVDLLALRAPHIVPTG"
     gene            complement(16941..17576)
                     /locus_tag="KOI47_RS09640"
     CDS             complement(16941..17576)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657538.1"
                     /locus_tag="KOI47_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_216215645.1"
                     /transl_table=11
                     /translation="MTRNDPPKAGTRGGLADKRRAILAGAFTVFARDGYTRASIDAIST
                     EAGVSTRTIYNHFRDKTELFETVIQQSAAEVARAQIAIIERELRKITDLEADLIAFGTA
                     WLTPTPDHAEHEALVRQINADTEHIPRAVLETWQRTGPLRVRKELAGRFRELAEDGLLR
                     IPDADRAARHFALLISEGDVAGRHGRQEEEIAETVAAGVRAFLYGYRA"
     gene            17675..18268
                     /locus_tag="KOI47_RS09645"
     CDS             17675..18268
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681197.1"
                     /locus_tag="KOI47_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_216215646.1"
                     /transl_table=11
                     /translation="MTRIGIILGSTRPGRRAGRVGDWVLEVAGRHPLVLAGTAEVELVD
                     LAEYRLPLLDEPEPAIRGRYRHEHTMAWAATIDSFDGFLFVTPEYNHSVSGALKNAIDF
                     LYREWHDKAAGCVGYGAAGAVRAVEHLRQILGEVGVATVRTQVALDKHTDTELFTDPDA
                     WVPGAEQTARLNLVLEQVVTWSKALGQRPAAARD"
     gene            complement(18265..19287)
                     /locus_tag="KOI47_RS09650"
     CDS             complement(18265..19287)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (31-336). E-value: 3.6e-21.
                     Score: 67.5. Matches aSDomain:
                     nrpspksdomains_KOI47_RS09650_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672870.1"
                     /locus_tag="KOI47_RS09650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_216215647.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.4e-22, bitscore:
                     78.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDTELTNHQFRLAARPQGLPQRTDWEYRTEPVGEPEEGQFLVE
                     VSHLSLDPAMRGWMNEGKSYIRPVRIGEVMRAGAIGRVIASRHQDFAVGEQVSGMFGVQ
                     EYAISDGRGVQRVDTRSAPPESYLGALGMTGMTAYFGLFDIGKPEPGQTVVVSGAAGAV
                     GSVVGQLAKIKGCRVIGIAGGEEKCRLLVDEFGFDAAIDYKSADLKAELRTHAPDGVDV
                     YFDNVGGEILDAVLARLALGARVVLCGAISQYNATEQVKGPANYLSLLVNRASMTGMVV
                     FDYADRYGEAAAELAGWLAAGKLRAREHVVEAGIETFPETLLSLFSGANVGKLVLKIRD
                     "
     aSDomain        complement(18280..19194)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS09650_PKS_ER.1"
                     /evalue="3.60E-21"
                     /label="KOI47_RS09650_PKS_ER.1"
                     /locus_tag="KOI47_RS09650"
                     /protein_end="336"
                     /protein_start="31"
                     /score="67.5"
                     /tool="antismash"
                     /translation="EPVGEPEEGQFLVEVSHLSLDPAMRGWMNEGKSYIRPVRIGEVMR
                     AGAIGRVIASRHQDFAVGEQVSGMFGVQEYAISDGRGVQRVDTRSAPPESYLGALGMTG
                     MTAYFGLFDIGKPEPGQTVVVSGAAGAVGSVVGQLAKIKGCRVIGIAGGEEKCRLLVDE
                     FGFDAAIDYKSADLKAELRTHAPDGVDVYFDNVGGEILDAVLARLALGARVVLCGAISQ
                     YNATEQVKGPANYLSLLVNRASMTGMVVFDYADRYGEAAAELAGWLAAGKLRAREHVVE
                     AGIETFPETLLSLFSGANVGKLVL"
     gene            19373..20374
                     /locus_tag="KOI47_RS09655"
     CDS             19373..20374
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164087.1"
                     /locus_tag="KOI47_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase domain-containing protein"
                     /protein_id="WP_216215648.1"
                     /transl_table=11
                     /translation="MGTTRSGESRAGVPLTNLDQPLFEQAGASKRDLVDYLDAVCDRIL
                     PGLRGRPLSVMRVLRGQAPFMQKNVPKYTPSWVRTVPVWAEASRREVSYALCDDRRTLL
                     WFGNQRAIEYHPTLARAEAMSRPTHLVLDLDPPADGEAEGEQGAEGFRQAARAALLVRQ
                     ALADSGLAGVVKTSGAKGLHVFVPIEAHQDMEDTAAATRALAARAERIDPALATTAFIK
                     ADRGGKVFLDPTRAGGATVVAAYSPRIRPGVPVSFPVAWTDLDRIAPGDFTIRNAVGLL
                     GSADPWAESMPAPQGLPADLIEEGHTIPVPRVAAMHEGKRRAKARREQQDTP"
     misc_feature    19847..19849
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20506..21183
                     /locus_tag="KOI47_RS09660"
     CDS             20506..21183
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673708.1"
                     /locus_tag="KOI47_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD family hydrolase"
                     /protein_id="WP_216215649.1"
                     /sec_met_domain="HAD_2 (E-value: 4.9e-10, bitscore: 38.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLRWATFDCFGTLVDWRHGIATGAELLFPGRGAELLPVYNRHE
                     PRVQAEFPTLRYREVMAEALRRTCAEAGLELLTADDAAVLAAGIAHWPVFPDTRAALTE
                     LRAAGWRLALLTNCDRDIIGESQRRLGVPVDAIVTAEDVGCYKPRHEHFTRFERTFGVR
                     REQWVHVAQSYFHDIVPAHELDIPRVWINRLAEDNDPAIADAVLPGLAGLADTVGRVYA
                     AAR"
     misc_feature    20698..20700
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21235..21250)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     misc_feature    complement(21265..21278)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.35"
                     /tool="antismash"
     gene            21297..21506
                     /locus_tag="KOI47_RS09665"
     CDS             21297..21506
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104522.1"
                     /locus_tag="KOI47_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5988 family protein"
                     /protein_id="WP_216215650.1"
                     /transl_table=11
                     /translation="MAGIKAELVGGPATLSDVDRRREVVDLAEQVKVSTGAGYEHFSHN
                     GQFNTAGGEKIAVFAWTGRTKIAE"
ORIGIN
        1 tctgtgacca gcgaatatcc gaagtcttga acctccgaac tgccgaacgt tgggagtggc
       61 gtgggtgctc cccgcacgct gggatggtcc ggccctgcgc cgtgactggc agctgttcgg
      121 cggcactccc cgtgcacagg ccgagtcata gcagccggat cgtgggcggc aaggcgctag
      181 acttgcgtcg gaagagtgaa gtagaaacag tgtttcggtt tctatcgtcc caggtcaatt
      241 agtgtgctcc ccgcacgcgc ggggatggtc ccgccgtgct cgagctggtg gccgagaacc
      301 tggtgtgctc cccgcacgcg cggggatggt cccgagatcg ggttacccaa gcgggactgc
      361 gccgagtgct ccccgcacgc gcggggatgg tcccatcgtc gtcttaccgc tctgccgggg
      421 caccgtgtgc tccccgcacg cgcggggatg gtcccgaggt cagcgaggat cccgcggcca
      481 ccatgaagtg ctccccgcac gcgcggggat ggtccctcac cgttatccat aagcagagtg
      541 aagtccacgt gctccccgca cgcgcgggga tggtccctgc tcgttcaccc agttccggat
      601 gtcgcccatg tgctccccgc acgcgcgggg atggtccgtc ggcgcgctcg ttggcgatcc
      661 agcgacgcat gtgctccccg cacgcgcggg gatggtcccc tggacagcac cgacaccgcg
      721 cacgtccggg agtgctcccc gcacgcgcgg gatggtcccg agcagggatg gcgcgaagcg
      781 atccgagagg cgtgctcccc gcacgcgcgg ggatggtccc agccgaggac gcgtccgggt
      841 gctggcgctg gcgtgctccc cgcacgcgcg gggatgggcc caggtcggtc gcaccggcac
      901 agtggctacg gcactgacga acgtcgctgg gcaaccgggt tttgtacgcg tcttgtacgc
      961 ggccggtcga ccatccggcc atggcatgtt cacagttccg gcgcatcgcc ggcagaacgg
     1021 tgaccgtgtt cgccgccgtc actggattgg tgctggcggg ggtcgttccg gcgggagcgt
     1081 ccgtcgacgg cacggtgcgc accgcgggcg gccccctgaa cgtccgccgc gcgcccacca
     1141 ccacgtccac cgtggtgggt tcggtggaca acggcaccaa ggtaaccatc gactgccaga
     1201 cgcacggtac ccggatcagt ggcgagctgg gcaccacgac gctctgggac tacgtgccct
     1261 cgctgggcgg ctacgtctcg gacgcctaca tgtataccgg ctcggacggg cagatcgcgc
     1321 cgagttgcgg ggtgggcacc ggcagcgcgg agtgctccac cgggggttgc gctggggagg
     1381 gcttgttccg ctccgaggac gcgaccttcg tggtctggga ccgctcaccg gacgggaagt
     1441 cggcggtggt ccagtactgg ctggctggcg gggtcggccc gctcgtcgtg cggcactcgg
     1501 gcggcagcgg caccagcacc gagcaggcga tcgaccttca gcccgatgac tgggtctact
     1561 acaaggtctg cgtccgggac tactccggcg gcacgggctt cgagtcctgc agcaacggca
     1621 tcaccgacta cgcggcctga cacaggggag gaacaaagcg atgagcgcag tcaatcgcag
     1681 gctggtgctg ctcggcgggc tggcgagcgc ggcgggcgcg atggccctac cgtccggggt
     1741 tccgtcctgg gccggcagca ggacgagtgc cgccgcccca ccgatccggg acccgttcca
     1801 gctcggggtc gcctcgggcg atccgctccc ggacagcgtg gtgctgtgga cccggctcgc
     1861 ccccgcgcca ctgaacccgg acggcctcgg cggcatgccc gacgccagct acgacgtgga
     1921 ctgggagatc gccaccgacg agaacttcgg ttccgtggtg cagcgcggca ccgtcgccgc
     1981 ggcccgcgcg cagggccaca gcgtgcacgt cgagccgcgc gggctggacg cgggccggga
     2041 gtacttctac cggttccggg ccggtggcca catctcaccc gcgggccgca cccgcaccgc
     2101 gcccgccgcg ggcgccacgg tcaaccagct caagtactgc ttcacctcct gccagcactg
     2161 ggaggaaggc tggtaccacg cccaccgcgg aatggcggag gacaaccccg acctggtgct
     2221 cttcctcggc gactacatct acgagaaacc ttccggccgc gggtcggcgg agaaggtgcg
     2281 cgggctcgcc gttcccgagg agacgaccac gctggcgctc taccgcgccc ggcatgccca
     2341 gcacaagacg gactacgacc tgcaggccgc gcatgccgcc gcaccctggc tcgtggtgtt
     2401 cgacgaccac gaggtggtga acaactggaa ctccaccacc gaccgggcca gcaacgcccg
     2461 caaggcggcc gccttccagg cgttctacga gaacaacccg atccgctcca gtgccaagcc
     2521 gaacggcgca agtatccagc tgtaccgcca gttcctctgg ggcaacctcg cccggttcca
     2581 catgctcgac acccggcagt accgcagcaa gcaggcgggc aggcacgact gctcggtgat
     2641 gcgcgaccgc agccgcacgc tcaccggaag cgcgcaggag cagtggctgc tgaacgcctt
     2701 cgagtcccac ccagccacct gggacttcct cggccagcag gtgttcttcg cacaacggga
     2761 caccgacggc cgcagcgcga cctgcgaccg ttcctccgac gcatgggacg gctacctcgg
     2821 ctcgcgggac cggatcaccc agggctggat cgaccggggt gtacccaacc cgatcgtgct
     2881 gaccggggac gtgcaccggc actgggccgc ggacctgcgc aaggactact tcgaccacag
     2941 cgacccgatc gtcggctccg agctggtcag cacctcggcg agcaccagca gcgccggggt
     3001 caccccgccc agcgacacct ggtactcgaa caacccgcac atccggtact acaagggcga
     3061 gcggggttac gtgcgggtca ccgccacccc cgagcagctg cgcgcggact tccgggtggt
     3121 ttccgacgcg ctggagcggg atccggcgaa ggtcaccatc ggcaccgacg ccagtttcga
     3181 ggtgcgggcg ggggagcgcg gactgcataa ggtctgacca gcgtctcgac ctccccggcg
     3241 accccgcgtg gcggactatt cttcgtaggt atactctcta cgtatacatg cgaagtctag
     3301 tgcttcgcgg gaaggggagg acgaggtgtc cgtcgcacac gtcctgctgg gcctgctgga
     3361 accggggccc cggcacggat acgacctgaa gcgcgcctat gacgtgcagt tcggccacga
     3421 caagccgctg gcttacgggc aggtgtactc cacgctgtcc cggttgctgc gcaacgggat
     3481 gatcgaggtg tccggcgtcg agcacggtga cgggccggag cgcaagcgct acaccatcac
     3541 cgacgccggg gtcaccgacg tcgagaagtg gctgacggcc ccggagagcc cggagccgta
     3601 cctgcagaac acgctctaca ccaaggtggt gctcgcgctg ctgtccggcc gcagcgccgc
     3661 cgccgtgctg gacacccagc gggccgagca cctgaagctg atgcgcaccc tcacccggcg
     3721 caagaacgaa ggcgacctcg ccgaccggct catctgcgac cacgcgctgt tccatctcga
     3781 ggcggacctg cgctggctgg agctgaccac cgcgcggctg gacgagctgg cgcaggcggt
     3841 gcgggcatga acccgggcaa cagcgcggaa aacaccgcgc ataccgcggg ctccgaaccg
     3901 gtgctggtgg ccgagggcat tgccaaggca ttcgggcaga ccgtcgcgct gcgcgatgcc
     3961 accgcctcgg tgggcgccgg cgagatgctc gccgtgatgg gcccctccgg ctccggcaag
     4021 tcgaccctgc tgcactgcct ggccgggatc gtgccgccgg actccggcga gatccgttac
     4081 cagggccgcg accttgccgc cctgtcggac cgggagcgca gtgccctgcg ccgcagcgag
     4141 ttcggcttcg tcttccagtt cggccagctc gttccggagc tcacctgcct ggagaacgtg
     4201 gccctgccgc tgcggctctc cgggatgcgg cgcaagcggg cggagaccga ggcccggtac
     4261 tggctgaccc ggctcgaggt ggaggaggtc gcggccaagc ggcctggcga cgtctccggc
     4321 gggcagggcc agcgggtggc ggtggccagg gcgctggtga ccgggccgcg ggtggtgttc
     4381 gcggacgagc cgaccggcgc gctcgactcc ctcaacgggg agaaggtgct gcacctgctc
     4441 accgatgccg cccggcacac cggcgccgcg gtcgtactgg ttacccacga gccacgggtc
     4501 gcggcctact ccgatcggga gatcgtggtg cgcgacggct cggtcagcga ccgggagctg
     4561 gtgggatgag cgggctgaag gacttcgcgc tggggctccg gctggccgtc gggggcggcc
     4621 ggatctccgg cgcggccttg ctgcggctgt cgatgaccgc ggtcggtatc gcgctggcgg
     4681 tggccctgct gttgctggcc acctccatcg gccacctgac cggggagcgc cgggaccgcg
     4741 tggcagcgac gcaggagatc accgatacgc ggccgggcgt ggatccgttg cggtggcaca
     4801 gcacgggcaa gcaggtgggc gaggactacc tcgagctgct cgcggtggcg ccgaccggtc
     4861 ccgccgctcc ggtcccgccc ggactggagc gccttcccgg ccccggcgag ctggtggtgt
     4921 cccccgaggt ggcgaaccgg ctggccaccc cggaagggga ctcgatccgg gccaggctgc
     4981 ccggcacggt ggtcggccag atcggcaagc cggggctggt cgatcccggc gacctccttg
     5041 tgtaccaggg gttcacccct gccgagctcg aggaacagct cggcgaggcg acgccggagg
     5101 aggtgtacgg gttcggcgtg cccagtgacg cgggggagat gtccgcgacg accctgctgc
     5161 tggtcgcgcc cgctgccgcg gtcctgctga tgccgttgct catcttcgtg accacggcct
     5221 cccggatggg cgcggcgcaa cgggaccggc ggctggccgg cctgcggctg ctcgggctgg
     5281 acgccaagca ggtgcgccgg gtcgcggcgg ccgagtcgct gctgggggcc atgctcgggc
     5341 tggtggccgg gatcgggctg ttcctcgcgc tgcggccgct gatcggctcg ctggagctgt
     5401 tcgggatgcg gttcttcgcc gcggacttcg tccccaaccc ggtgctcggc gcgctggtgc
     5461 tgttgctggt ccccgcgctc gcggtcggcg ccgcgctgtt cggcctgcgc cgcaccatcg
     5521 tcgagccgtt gggcgtggtc cgccagggca ggacgacacg gcgccggatg tggtggcgct
     5581 ggctgctcac cggggccggt gcggtgaccc tcgcctgcac cctgttcatc ccgctgagca
     5641 gccgcggttc ccttgccgca ttcctgctgg tcggggggac cgtgctgctg ctgttcggaa
     5701 tcgtttccgt gctgccgtgg gcggtggaga agctggtgcg ggcactgcgc ggcggctcgc
     5761 cctcctggca gttcgcggtc cggcggctac agctggacag cggtaccccg agccgggtgg
     5821 tgtccgggct cgtggtggta ctggccggga ccatcctcat ccaggggctg ctggcctcgg
     5881 tgggcagcgc cgaggagatc cccgcgcgcc cgctggcgca gaatccgggc ccggtgcggg
     5941 tgcaggtcga gcaggacgac ctgccggagg tccgcacccg gctggccgag gtcgccgagg
     6001 tgaccggaac caggctgatc cggcaggcga ccgtgggtga gtcgccgggc cagggcagtg
     6061 cggcgacggt ggagatcggc gactgcgcgg cactggcggc cagggccacg ctcggcccgt
     6121 gctcggacgg cgatgtcttc tatgtgccgt atcccgagca gtacgactac cgccccggac
     6181 cgcccccgcg gaacgtgatg ttcctcggcc aggacgagcg gggctccgct gccgaatggt
     6241 cgattcccgg cccgatccgg gagatcgcgc cgcggcatgc ggaaaagtat ctgggcggta
     6301 ccgtgctggc cacgccggga gcgctcgggg acaccccgat gcccgcggac gccaggctga
     6361 tgctctacgt cggtggtacg ggaaccattc ccgaactggc cgaccaggtg gcgctggccc
     6421 tgcgcccgct ggggctgcgc accgacatca gctacgccag gtccaccagc ttcagccagg
     6481 tggagaacga gcgcatcgcg aacttccgcg cggcgctgct gaccgcctcc ctgttcgtgc
     6541 tcgtggtggc cgcgctgagt ctgctcatgc tcgcggtgga gcagatcacc gagcggcggc
     6601 gcgcactggc ggcactgtcc gcggccgggg tgcccctgtc ggtgctcggc cgggcctcgc
     6661 tgtggcagac ggcgattccg gtgggcgtgg gcgtggtcct cgcggtcgcc gcgggcatcg
     6721 gcctgaccct gcccagcttg cggctggcgg atgtgcccat cgcgatcgac gcgacggcga
     6781 tcctcgggct gtccgccgcg gccgtgctgg cggtgctgct ggtcaccgtg ctcaccctgc
     6841 cgttgctgcg ccaggtcacc aaactggacg cgctgcgcgc cgagtagcgg gtctcgtcgt
     6901 ccggggatta ccagtggtca ctgtgactgc gctctctgtc gatcactgtc gccgtgaact
     6961 tcacaccgca ctagaatctc ggtccggtat cgggttgccg gatgggttcg gtgcgcacgc
     7021 ggcgacgagg aggcgtagct atggcggtgc cggccgctgg ggcgctgagc gagaacggtg
     7081 ctggtcaggc gaccatcgcc cggatctgcg actactggct cggcggttcg cagcacaccg
     7141 aggccgaccg gcgcgcgggc gaccacatcc tgctgtgcgc cccgcacctg gcctacgtgc
     7201 tgcgcaccca gcaggcgcag gtcgaccgga tggtgcgcta tctgaccgcg gcggggatcc
     7261 ggcagttcct cgacctcggt tcccggctgc ccaccgcggg caatgtgcat gagatcgcgc
     7321 gggagtgcat cccggagagc cgggtgctct atgtggacca cgacaccgag gtggccaggg
     7381 acggcgcgcg gttgctcgcc ggggacgagc gcgccggttt cctgcacgcc gacccgctgg
     7441 acccggtgca ggtactcgga tcgtcggcgt tgcgcggtct gctcgacctg cgtgagccca
     7501 ccgcggtgtt gatgacgaac ctgctgcagc acgtaccgga ctccgcggac ccggccgcgc
     7561 tggtcggcag gtacgtcggt gcggtgagcc cgggtagcta cctgggaatc tcgcacttcg
     7621 gctcggacga gcaactggtc accggtctcg ggatgttcaa ccggatgttc ggcacccctc
     7681 ctccggtcac cctgcgcgag cccgagcaga tccggccgtt cttcgccggg ctcgagctgg
     7741 tggaacccgg tatcgtgccg ttgccactgt ggcggcccac ggaagtggcc ctggacgacc
     7801 gcaacccgga ggagttccgg gtgtacgtgg gcctcggcca caagcgcctg ccgggttagg
     7861 caccggtgcc gccggggacg gccagcgccg ccgccagcag cagcaggttg ccgagcacgg
     7921 ccggggtcag cgcgtagcgg atcatccggc ggaccgccgt gggatcacgc agcagagcca
     7981 gcgtcccgcc gaggaacgcc ccggtcccga gcattccggc cagcgcgagc agggcgccgt
     8041 gccaccacca caggccgatg ccgagcagcg ccaccccggc tccggacagc gcgcaggaca
     8101 gggcgagcgc ccgtcccgtg ccatatcgga cggccggggt gcggaagccg gtggccgcgt
     8161 cggcggcacg gtcggtcacc gagaacaggg cggtgcggcc ggtgcccagt acgccgagtc
     8221 cgaacacgac cagccccatc gcggggtcga accgcgcgcc ggccgcggcg aaggacagca
     8281 ccaccggcaa cgccatggtg gcgcagccga aggctgccgg gccgaggaag ccgcggcgtt
     8341 tgagccgtac cggttccagg ttgtacagca ggtgcaggcc gaggatgagt accccggcca
     8401 tggcgaccgg ccaccggccg gaccagaccg cggcggcaag ggccagcgcc agcccggcga
     8461 ccgcttcggc agtggcccag cgccggatcc gtgccctccc cacggcccgc gccaccccgg
     8521 cctgccggaa cttgtgccgg tgcctggcgt cggtgccggt gtcggccacg gtgttcacgg
     8581 ccatcccggc ggtggtgagc agcaggttgg ccccgatcgc tggcagcgca ggacccggca
     8641 gggcggcacc ggcgaacgcg gctccccagc tcgcgtaaca caggtagctg agccagagcc
     8701 cgtgtccgag ccggtgcacc gcgacgacct cgtgaaccgc cactcgccgc gtggcccggc
     8761 tctcagccac gatcgccggt cacccgcatc cgcagcgccg ggtcgggggt cagcaggttc
     8821 ccgcggatcc ggacccgtcc ggcgccggga ttgacgcagt gccagtgcct gcgccgcaac
     8881 agctccgcga ccagcatccg gatctccagc tgggccagcc cgctaccgag gcagcgccgg
     8941 gtgccgccac cgaacgggaa gtagtgccgc ggtgggcgag taccgaggaa ccggccgggg
     9001 tcgaaccgcc gcggggcggc gaacgcctcc ggcctgcggt gcgccaggta gatgctcaac
     9061 gtgcagacgg tccccgcggg gaaccggcga ccgcccagtt cggtctcctc ggtgagcatc
     9121 cggttctccc cgatggccgt cgagggggtc agccgcagta cctcctggat caccgcctgc
     9181 agcagtggtg tccgggtggc atccgatccg tccgcatcgg catcggccag ttcggccagc
     9241 accgcctccc gcagccgccg gtcgcggtcc agccacagca gggtccaggt catcgccgtc
     9301 gcggtggtct cgtgcccggc gaacagcagg gacacgatct ggtcccgcag ctcggcctca
     9361 ccgagctcgc cgatcgggcc gtccccggac agcagcagcg cggcgagcgt ggcctgaccg
     9421 tcatcgtgtc cggccctggc cgcgcgtacc agcgcccggt ccaggtccgg gccggaacgg
     9481 gggagccgca cgccgaggaa gcggtaggcg aggccgcggg tgcgggagcc gaaggcacgc
     9541 cgcagccagc cgccgaactc cgccagcatg cccggctctg gcgcacccag cacgatccgc
     9601 ccgatgatcc gcagggcgag cttccgggtc cacgctgcga gggggaccac cgtgccgggg
     9661 cgcagctcgt cgatcgctgc gcgcaggtgg cctgcgatga tctcccggtg tccggtgagg
     9721 gcgcggccgc gcaacgccgg gccgagcacc ctgcggtagg cggcatgccg ttcgccgtcc
     9781 gcccacagca acgaaccagg acccagcagc ggggtcaggc tccggctgcc gggatgggcc
     9841 agccgccggt cggaccggaa gatctcctcc agcacctccg gatgccacac cagcaggcgg
     9901 ggagccgtgc cggggcgcag ctccaccatg ccgtcggggg agtccgcgat ggcgttcagg
     9961 tacgccagcg ggcgcaccgc cagctgcagc tccgcgcggt tcacgagggc tcgaactcct
    10021 ggccggtcac cggctccgcc agcaacgcgg agaccgccgg atcggtgtgc gcgagatgca
    10081 gggcggcaag ggcttccgcg cgcacgatcc ggagtggcgt gtacaggtcc ttgtcatgcc
    10141 acagtggagg gtgctcggca tcctggtccc agtgcagcag ggagagcgca ccgtgcgcgg
    10201 cggcccgcgc gatcgcgtca ccggtgcgcg ggaccctggt gttcagcagg atcttcaccg
    10261 cgtacgcggt ctcctcgtag gtgccgcccc accgccccca ggtgccgtca tcgtgctggc
    10321 tcagcagcac ccagtccacc gcgccgcgca ccgcggaccg tgcggcggct ccgccgtagt
    10381 cggccagcgc ggtggcacag caggcggtgg cgtagtacgg ggaggcgtgc cacttgtcgg
    10441 cccagctgcc gtcgggacgc tgctgctcgc acaaccaggc caccagcccg gtcagggcat
    10501 cggcgtaacg tgccggactc gcggggtggg tggccagcca ggcgccgaat gcctgcaaca
    10561 catgggcgtt cgccgtggtc gagggtgtgc gttcggccgg gaagcagtgg aagtgcctgc
    10621 ccgtgcggta cttccacagg ctgtccggtt cccgcggtct gccgagtagg gccagcgcgt
    10681 acagggcggt ggcggtgtcg tcggcgtccg gtgggagccc ggttccgccc gcggctcccg
    10741 attccgtcag tgccgcgtcc accgcatcgg caggctcgcc gtgcgcgggg agccccagtc
    10801 cagaactggc caaagtggac agtatccagg agcgttcgaa cagtgcgagc ggggcggcca
    10861 ccggtaccgc gccttccggc ccccgcacgg cttccaggta ggcaaggcag ggagacccgc
    10921 ccggcacggc ggtttccgtg ccgagccatg ccgcggtggc ggcgggggag cagccgaccc
    10981 cgtgctcggt cggtccggcg aaggtggctc ccctggcagg cgggccgatg atttccagtg
    11041 agtgcaggag cttgcccggc agctcgcggc cgtgccgcac cgcctcgcgc agggagccga
    11101 gcagctccgg ccgcgcgcct gccgggatcg gcagccggtg tccgtgccat tccgccaact
    11161 ccgccggtgc cggggcttcc agtagccggt tgatgtcgat gatcagcccc ggcacgatga
    11221 gctcgaccgc caccgtgtcc ggaagggacg gtcccgcacc ggttcgggcg gcacggtcca
    11281 tcgcgtccag tccccgggct gtcgccgcgg cgatgcgctc gccagcgccc ggcatctccc
    11341 tgcggtgcag tacgcgcagc agtgcctcga tcgcgctgag cgtgggcacg aaccggtagt
    11401 cgtccggccc gccccaggtg ccgtccggtc gctgccggtc gagtacgaac ccgatccggt
    11461 ccttgtgcgc ggggagcgtg ggggccagtg agatcaacct ggccgtctcg tagaccgacg
    11521 gggagaacga tccgtaggca tcggcggccg attcggcgag aagttcggtg acggcgcggt
    11581 gcgcttgggc ggtccaggac tcgtgcagat ccactcgaag ccccctggca gttcaggctc
    11641 catcgacgac cgggcagcgc acggccgccg ctgttgggta actggactga cacttaacgt
    11701 agcacccgcg ggcggccgat cgtgccgact tgattcgttt ggagtagtcc tgaaccgtta
    11761 aacgacgtac gcacctccca cccgaggtcg gcggcaccgc cccagaacgg cccatccagg
    11821 gagggtgccg gtcgacctgg aacggcgggt cagcccacct cgatgacgat cttgccgcgc
    11881 ccgtggccgt cctcgctgag ccggtgcgcg tcggcgatcc gttccagcgg gaaggtctgc
    11941 tggatcggca gccgcagcgc gccgctttcc agcatgggca gcacctcggc gaacacctcg
    12001 ggcagcgggg ccgcatccgg cccaccgccg gagaaacgca ccccgtgcgc ccccgcgttg
    12061 ccgtcggcga tcgtgagcac cctgtccggg tccccggtca gctccacgga gaggccgagc
    12121 acgtcccggc ccgcggcgtc cagcaccagg tccaccgagt ccgtgacacc gcgtacccgc
    12181 tccagcaggc cctcgccgta ctccaccggg cgcaccccga gttcggtgag gaagtcgtgg
    12241 tgccccctgc tggccgtgcc gatcaccgtc gcgccccggc tgagcgcgag ttgcgcggcc
    12301 accagcccga ccccgcccga cacggcgtgg atcagcaggg tgtggcccgc ccgcagcccg
    12361 agatcgcgca gggtgcggta ggccgtctcg gcgaccaccg gcagccccgc ggccagcggg
    12421 aaggacagcc agtccggctt ggccaccagg ccgtcggcgt cggcgagggc gtgcgtggcg
    12481 acggccccgg tcgcggcctt gccgaacacg gcggtccccg gacgcaggga gcgcactccc
    12541 tcgccgaccg catcgaccgt ccctgccagg tcgaacccgg tgccctgtgg ctcatccggg
    12601 gcatcggagc ccgcgaagaa tccgcttcgg atcttccagt cgatggcgtt caccccggcc
    12661 gcggcgaccg cgacccggac ctggccccga cccggctcgg gaagcgggac ctcctcgacg
    12721 gtcagtacct cggggccgcc gtaacggctg aaacgggctg ctttcggcat cttttccacc
    12781 ctcctgtgtg gatagtgcgg tcaggcgagc agcagggttc gtccgacgac ctccctggac
    12841 tcgatggcgg catgtgcctc ggccgcccgc tccagcggga aggttcgccc gatcaccggg
    12901 gtcaccctgc cctgcgcggc cgcccgcagc acctgcccgg ccagccgggt gccgtccgcg
    12961 ggcgcgaact gcacctgctc gattccggtc acggtgatct cgcgccgctg tgcctcccct
    13021 gcgtcgatct cggcgaaccc gccgctgggc acaccgtagg cgaacatccg gccgccccgc
    13081 gcggcgaggc tgaaggcggc cgcgccgagg tccccgccga ccccgtcgaa caccacccgt
    13141 gggcccccgg tcgccgcgct gacccgcgcc gtccagtccg gctcggtgta gtccacggtc
    13201 agctcggcgc ccagctgccc ggccgcatcc agtttccgtg ccccgcccgc ggccgccacg
    13261 accctggcac ccgcggcgcg ggccagttgc accagcagca ggccgaggcc gccgccggcc
    13321 gcggtgacca gtacccactc gcccggttcc agcgctgccg cctcgaccag gctgagcgcg
    13381 gcgggtccgg tctggagcag ggccgccgcg tccggcaggc tcagctcgtc cggaacatcg
    13441 accagcccgg ccgcgtcggc gaggacccgc tcggcgtacc cgccgccatc ggtcatggtg
    13501 accacgcggc gccccaccag gtcttcgggt acatccgggc cgaccgacag caccgtgccc
    13561 gccaccccgc cgcccggcac ataaggcggg tgcagcggga agtgctcgcc accccagccc
    13621 gagcggagct gggtgtccag gaacagcacg tcggcgacgg ccacccgcac cacgacctgg
    13681 ccctgcccgg cccgcacatc cggaacctgg cgcacctcca gcacttccgg tccgccgaac
    13741 ctggtcacct gcactgcccg catgccgctc acgctccttg tccgcccgtt cccctggtgc
    13801 cgagaccagc atggaatctc gagctgacta gaggtcaagg tggcgtgtgc cggcccgctc
    13861 cgtgccactc agccgggcac ggcgccgtgg tagaagtaca ggccgagccc gatggtgaag
    13921 atgagcatgc cgtacagcgc gtgctcgaag gacaccgtga acagcgacct ggtccgccgg
    13981 tacctgctgg cgaagatcca gccgccggca agggaaagca cgatcgcgat ccagttgccg
    14041 aacggcaggt gcacgaaccc gaacgcggcc gcgctcgcgc ccaccatgcc gtgcccctcg
    14101 ccgaacaccg gggcgtaacg ctggaacagg aacgcgcgga agatcagttc ctgcgggtac
    14161 acactggcca gcggatacag caccatgacc agcgcccagg tcagcggttc ctcccggggc
    14221 agggtgaaca gcagctcggg acgcgcgatc gccaccacgg cgcccgcgcc gaccgcggtc
    14281 actccccaga gcaggccgat cgaccgcaac tggccgggca gcgcgtccgg ccgccacaac
    14341 gcggaacggt cgaatgcggg cgagcgcagc aggtacatga ccacggcggc gccgagtacg
    14401 agcaacaccg gaatcggact ggtgccctgg aacagcaggg tgtagagcac gaccaacccg
    14461 aagaacagca ccgtgtactc cacggcgagg tagagcctga tcggtggcgc ggccagcatg
    14521 cggatcacgc taccggcggt ttcctgagag tctgttccag gatcggccgt ggctcctcat
    14581 ccggtggcga cggcgtcgat ctcgaacgcc atctccggaa gggcgagcgc ggccacgccg
    14641 atgagggtct gcgcgggcgg tcgctcgccc cagatctcgc cgagtactcc ggtgatggtc
    14701 tccagcttgg ccgcgtcgtg ccccaccacg taggtgccga ggcggaccac gttccggtag
    14761 ccgaggccga ccgcgcccag tgcggtaccc aggttggcca cggcctgccg cacctgggtg
    14821 gcgaagtccg ccgagacgac ctggccgtcg gcgccggagc cgtactgccc ggcgacgaac
    14881 accagccttc ccgcgggaac ctcggtgaga tggctgtacc cgaacggcac cggatcatgc
    14941 agttctgcgg gattgacgat ggtgtgtgtc atgccgcgct cccgctgccg ggccgctcgt
    15001 cggtgccggg caccttggcc gtgctgatcg cgatccggtt ccaggtgttg atcgtgcaga
    15061 tcatcgtgat cagggtggcg aggcgggtct cgtcgaacga ggctgccgcc cgccggtaga
    15121 cctcatcagg gaccccgtcc accgacacct tggtcacggc ctcggtcagg tccagtgccg
    15181 cctgctcctc ctcggtgaag aagccggtgg cctcccgcca gaccgccacc atgtgcaggc
    15241 gctgctcgtc cgcgcccgcc ttgcgggcgt ccgaggtgtg catgtgcagg cagtaggcgc
    15301 agtggttgag ctgcgatgcg cggatctgca ccagctccac cagcgccggg tcgaggccct
    15361 cgcgcgcggc ggcgtcgaaa ccgatcagcg ccttgaaggc cttcggggcg gccttggtga
    15421 tgttgactcg ttgcatgccg ttgttcgtca tggtcacgac gctacggctg gaatcgaccg
    15481 gttgtatggt gcatttccat ggaggattcg tgggtcaatt gggccgagcg ggtgggccgg
    15541 gacctgcatc tcgagctgcc gggaaagggc gggcgccggg ccgcgctgat ccgcgctctg
    15601 cgggaggcga tccggaccgg gcggctcgct cccggcaccc gcctcccgcc ctaccgctcg
    15661 ctggccgccg acctcggcct ggctcggaac acggtggccg acgcctacgc cgagctggtc
    15721 gccgagggct ggctcacggc gcgccaggga tcggggaccg cggtggccat ccgcgcggag
    15781 ccgttgcctg ccggcaggag ccgggcacga gcggggccgc gactcaccca cgatctgcgg
    15841 cagggccagc cggatgccgc ctccttcccg cgcaccgact ggctggcctc cgcccgtcgc
    15901 gcgctgctcg ccgcgccgac cgaggcgttc gggccggggg acccgcgcgg tcgccccgag
    15961 ctgcgccgcg cgctggccgg ctaccttgcc cgggtgcgcg gggtgcgcac cgaacccgag
    16021 cggatcgtga tctgtgccgg gttcgcgcac gcgctgcggt tgctgttcgg cggcggggtg
    16081 ctgggtggcc cgctggcggt ggagtcctac ggcctggact tccaccggtc gctgctggcc
    16141 gaagccgggg tgcgcacgat cccgctgacc ctggacgagc acggtgcggc cgtggcggaa
    16201 ctcaccgggc tgcgcgaggt ccggaccgtg ctgctcaccc cggctcacca gttcccgacc
    16261 gggggtccgc tgcatccgca gcggcgctcc gcggtggtgg agtgggcggg tgccagggac
    16321 ggcctgctgc tggaggacga ctacgacggg gagttccgct acgaccgcca gccggtcggc
    16381 gcggtgcagg ggctggaccc cgaccgggtg gtgtacctcg gttcggtcag caagagcctc
    16441 tcgcccgcgg tgcgccttgg ctggatggtg ctgcccgagc acctggtgga cacggtgctg
    16501 cgggtcaagg gggagcggga gggctgggtc ggtgtcgccg accagctgac cctcgccgac
    16561 ctgatcgagt ccggcgcgta cgaccggcat gtccggcgga tgcgccagcg ctaccggcgt
    16621 cgccgggacc agctggtgga cctgctcgcc ctgcgggcgc cccatatcgt gcccaccggc
    16681 atcgcggccg ggctgcacgc ggtgctccgg ctccggccgg gtaccgagcg ctcgatcctg
    16741 gacgcggcag gctggcaggg cctcgccgtg gacggcctgg ctcccttccg gcatccggag
    16801 gccaccatgc cagccgccga ggggctcgtc gtcggctacg ccaccccgcc cgagcacggt
    16861 taccccgcgg cgatcgaggc actgtgcggc gtgctgccgc cgccgtaact cagtgcccgg
    16921 tagccacaaa gggccgtaac tcaggcccgg tagccataaa ggaacgcccg cacgcccgcg
    16981 gctaccgtct cggcgatctc ctcctcctgc cgcccgtgcc tgcccgcgac gtcgccctcg
    17041 gagatgagca gcgcgaagtg ccgtgccgcc cggtcggcgt ccgggatgcg cagcagcccg
    17101 tcctcggcca gttcgcggaa gcggcctgcg agctccttgc ggacccgcag cggcccggtt
    17161 cgctgccagg tctcgagcac ggcccgcggg atgtgctccg tgtcggcgtt gatctgccgt
    17221 accagggcct catgctcggc gtggtcaggg gtcggggtca gccaggccgt gccgaaggcg
    17281 atgaggtcgg cctccaggtc ggtgatcttg cgcagctcgc gttcgatgat ggcgatctgc
    17341 gcccgcgcca cctcggcggc gctctgctgg atcacggtct cgaacagctc cgtcttgtcc
    17401 cggaagtggt tgtagatggt gcgggtggac acgccggcct cggtcgagat cgcgtcgatg
    17461 ctcgcgcggg tatagccgtc ccgtgcgaac acggtgaagg caccggcgag gatcgccctg
    17521 cgcttgtccg ccagcccacc gcgagtgcct gccttcggcg ggtcgttcct ggtcatagtc
    17581 gccccctcga ctcgtttgca cgaatcgttt tacctgttgc catatacgtt gtactttacc
    17641 cgggtaggtc gaaacgcgca gggaggcaag gcagatgacc cggatcggca tcattctcgg
    17701 cagcacgcgc cctggcagga gagcaggccg ggtgggggac tgggtactcg aggtggcagg
    17761 caggcacccg ctggtgctgg ccggtacggc cgaggtcgaa ctggtcgacc tggccgagta
    17821 ccggctgccg ttgctggacg agccggaacc ggcgatccgc ggccggtacc ggcacgagca
    17881 caccatggca tgggccgcga cgatcgactc cttcgacggg ttcctgttcg tgaccccgga
    17941 gtacaaccac tcggtttccg gcgcgctgaa gaacgcgatc gacttcctct accgggaatg
    18001 gcacgacaag gctgccgggt gcgtcggtta cggcgccgcg ggggccgtcc gcgccgtgga
    18061 gcacctgcgc cagatcctgg gtgaggtggg ggtggccacc gtgcggacgc aggtcgcgct
    18121 ggacaagcac accgacaccg agttgttcac cgatcccgat gcctgggttc ctggcgcgga
    18181 gcagaccgca cggctgaacc tggtgctgga acaggtcgtc acctggtcga aggcactcgg
    18241 gcaacggcct gccgccgccc gtgactagtc gcggatcttg agcaccagct tgccgacgtt
    18301 ggccccggag aacaggctca gcagggtctc agggaaggtc tcgatccccg cctcgacgac
    18361 gtgctcgcgg gcgcgcagct tgcccgcggc cagccagccg gccagctccg ccgcggcctc
    18421 gccgtagcga tcggcgtagt cgaagaccac catgccggtc atcgaggcgc gattgaccag
    18481 cagcgagagg tagtttgccg ggcccttgac ctgctcggtg gcgttgtact gggagatcgc
    18541 cccgcacagc acaacccgcg cgccgagtgc gagccgggcc agtaccgcgt ccaggatctc
    18601 gccgccgacg ttgtcgaagt acacgtccac cccgtccgga gcatgcgtgc gcagttccgc
    18661 cttcaggtcg gcggacttgt agtcgatcgc cgcgtcgaag ccgaactcgt ccaccagcag
    18721 ccggcacttc tcctcgccac ccgcgatccc gatcacccgg cagcccttga ttttggccag
    18781 ctggccgacc acgctgccca ccgcgcccgc ggctccggag acgaccacgg tctgccccgg
    18841 ctccggcttt ccgatgtcga acagtccgaa gtaggcggtc atcccggtca tcccgagcgc
    18901 gccgaggtag ctctccggcg gtgcgctgcg ggtgtccacc cgctgcacgc cacgaccgtc
    18961 ggagatggcg tactcctgca cgccgaacat gccggacacc tgctcgccga cggcgaagtc
    19021 ctggtgccgg gaggcgatca ccctgccgat cgcgcccgcc cgcatcacct cgccgatgcg
    19081 caccggccgg atgtaggact tgccctcgtt catccagccg cgcatcgcgg ggtccagcga
    19141 gaggtgcgag acctcgacga ggaactgccc ctcctccggt tcgccgaccg gttcggtgcg
    19201 gtactcccag tccgtgcgct ggggtaggcc ctgcgggcgc gccgcgagcc ggaactggtg
    19261 gttggtcagc tcggtgtcag tgctcatgcc cgcatcatac cgaccggtcg gtaccgcggc
    19321 aggtccggca tccgctgttg accgggacgg gtgagcacgg tgaggtggac ccgtgggaac
    19381 cacacggagt ggcgagtcac gggcgggcgt gccgctgacc aacctcgacc agccgctgtt
    19441 cgagcaggcg ggggcgagca agcgggacct ggtggactac ctggacgccg tctgtgaccg
    19501 catcctgccg ggactgcgcg gcaggccgct ctcggtcatg cgggtgctgc gcggccaggc
    19561 gccgttcatg cagaagaacg tgccgaagta caccccttcc tgggtgcgca ccgttccggt
    19621 ctgggcggag gcctcgcgcc gggaggtctc ctacgcgctg tgtgatgacc ggcgcaccct
    19681 gctgtggttc ggcaaccagc gcgccatcga gtaccacccg accctggccc gtgccgaggc
    19741 gatgagccgt cccacccacc tggtgctgga cctggacccg cccgccgatg gggaagccga
    19801 aggggaacag ggggccgagg gcttccggca ggccgcgcgg gccgcgttac tggtgcggca
    19861 ggccctcgcc gactccgggc tggcgggggt ggtgaagacc agcggcgcca aggggctgca
    19921 cgtgttcgtg ccgatcgagg cgcaccagga catggaggac accgcggcgg cgaccagggc
    19981 actggcggcc agggccgagc gcatcgaccc cgcactcgcc accacggcgt tcatcaaggc
    20041 cgaccgcggt ggcaaggtgt tcctcgaccc gaccagggcg ggcggcgcga ccgtggtcgc
    20101 cgcgtacagc ccgcgcatcc ggccaggggt cccggtgtcc ttccctgtgg cctggacgga
    20161 cctggaccgg atcgcgccgg gtgacttcac catccgcaac gcggtggggc tgctcggatc
    20221 cgccgatccg tgggcggagt cgatgcctgc cccgcagggc ctgcccgccg acctgatcga
    20281 ggaggggcac accattccgg tgccccgcgt cgccgcgatg cacgagggca agcggcgagc
    20341 caaggcgcgc agggagcagc aggacacccc ctgaccccgt ggtggcctgg ccacccttcc
    20401 ctgtccccgt tctcggcacc cgagcgggtc gcggccgtcc ttgccgtttg tctgactgta
    20461 tagcagactg acagtctgac gggatcggaa ggaaggacgc cgctgatgag tgacctgcgc
    20521 tgggccacgt tcgactgttt cggcacgctg gtggactggc ggcatggcat cgcgaccggg
    20581 gcggagctgc tgttccccgg ccggggagcc gagctgctcc cggtctacaa ccggcatgag
    20641 ccgcgggtgc aggccgagtt ccccacgctg cgctaccgcg aggtgatggc cgaggcgtta
    20701 cgccggacct gcgccgaggc cgggctcgaa ctgctcaccg cggacgacgc cgccgtgctg
    20761 gccgccggaa tcgcccactg gccggtgttt ccggacaccc gcgccgcgct gaccgagcta
    20821 cgcgccgcgg gttggcggct ggccctgctc accaactgcg atcgggacat catcggtgag
    20881 tcgcaacgca ggctcggggt gccggtggac gcgatcgtca cggccgagga cgtcggttgc
    20941 tacaagccga ggcatgagca cttcacccgg ttcgagcgga ccttcggggt gcgccgggag
    21001 cagtgggtcc acgtggcgca gagctacttc cacgacatcg tgcccgcgca cgagctggac
    21061 atcccgcggg tgtggatcaa ccggctggcc gaggacaacg acccggcgat cgccgacgcg
    21121 gtgctgcccg gcctggccgg tctcgccgac acggtcggca gggtgtatgc cgccgcgcgc
    21181 tgacgttttc tccgtcctgc gccgcttgac agttcacggc gaagtccgca agattgtgat
    21241 gcagagcaca gtgttctggg gtcgttttat cgatcaattt gccccgaggg gatgccgtgg
    21301 ctggaatcaa ggctgaactg gtcggtggtc cggccacgtt gtccgatgtc gaccggcgtc
    21361 gtgaggtggt cgacctggct gaacaggtca aagtgagcac cggtgcgggc tatgagcact
    21421 tctcgcacaa tggccagttc aataccgcgg gcggggagaa gatcgcggtt ttcgcctgga
    21481 cggggcggac caagatcgcc gaatgaggaa ccggccgcgc cgcgacgggt ggttttcagc
    21541 cgaggtgttc ggagatcgtc cgtagcacct ccgcctgttg ctggccgaga tagaagtgcc
    21601 cgccagggaa cacc
//
