LOCUS       NZ_CP076538            21101 bp    DNA     circular CON 16-DEC-2024
DEFINITION  Amycolatopsis aidingensis strain YIM 96748 chromosome, complete
            genome.
ACCESSION   NZ_CP076538
VERSION     NZ_CP076538.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis aidingensis
  ORGANISM  Amycolatopsis aidingensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     YIM 96748 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2021) Yunnan University, Yunnan Institute of
            Microbiology, 121 Street, Yunnan 650000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdevono v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018885265.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:59:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,118
            CDSs (total)                      :: 7,060
            Genes (coding)                    :: 6,941
            CDSs (with protein)               :: 6,941
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 44 of 119
            Pseudo Genes (incomplete)         :: 87 of 119
            Pseudo Genes (internal stop)      :: 2 of 119
            Pseudo Genes (multiple problems)  :: 13 of 119
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:56:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1218966
            Orig. end                         :: 1240067
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="5"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11101](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11101
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    589..604
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.01"
                     /tool="antismash"
     misc_feature    689..704
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    871..884
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            2660..4117
                     /gene="ahcY"
                     /locus_tag="KOI47_RS05920"
     CDS             2660..4117
                     /EC_number="3.13.2.1"
                     /GO_function="GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahcY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019810070.1"
                     /locus_tag="KOI47_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosylhomocysteinase"
                     /protein_id="WP_216214650.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.3e-09, bitscore:
                     35.5, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKFQKVGGLEFAVADLSLAEAGRHQIRLAEHEMPGLMATRKEY
                     ADSKPLKGARIAGSLHMTVQTAVLIETLVELGAEVRWVSCNIFSTQDEAAAAVVVGPNG
                     TPAKPEGVSVFAWKGETLEEYWWCTNQLFQFGDKGPNMLLDDGGDATLLVHKGVEFEAA
                     GAVPETDANDPDEYKVVLATLRKSLAEDTKRFTRIAEGIKGVTEETTTGVHRLYEFAKS
                     GELLFPAINVNDSVTKSKFDNKYGCRHSLVDGINRATDTLIAGKVAVIAGYGDVGKGSA
                     ESLRGQGARVIITEIDPICALQAAMEGYEVTTMDEVVDKADIFVTTTGNFDIITAEHMS
                     KMKHQAIVGNIGHFDNEIDMAGLEKIPGIKKVEIKPQVHEYVFPDGHSIIVLSEGRLLN
                     LGNATGHPSFVMSNSFANQTIAQIELFTKTDEYDKQVYVLPKHLDEKVARLHLDALGVK
                     LTKLTKEQAEYIGVDVEGPYKPDHYRY"
     gene            4209..5096
                     /locus_tag="KOI47_RS05925"
     CDS             4209..5096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019815307.1"
                     /locus_tag="KOI47_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mycobacterial-type methylenetetrahydrofolate
                     reductase"
                     /protein_id="WP_216214652.1"
                     /transl_table=11
                     /translation="MNTIALELVPPEIEGGEQRAAEEGQKVAELCRASGLTEAIQHVMI
                     PGMIAEDDDRPVEMKPRMDVLDFWNALRPELGAMRGLCTQVTAFHDKQALTSRLNELRD
                     SGMDGIIFVGVPRTMNDGDGPGMAPTDALAEFTGVVPNRGVILIPTRDGELGRFGFKCD
                     QGATFGMTQLLYSDAIVGFLRDFAKQSEHRPEILLSFGFVPKVEQRIRLIDWLIQDPGN
                     PAVKEEQEFVAKLADSTFAERKHELVELYKRVTDGVRELGFPLSIHLEAPYGVSKPAFE
                     VFGEMLDHYSPLAS"
     gene            5228..5443
                     /locus_tag="KOI47_RS05930"
     CDS             5228..5443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082076.1"
                     /locus_tag="KOI47_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_216217771.1"
                     /transl_table=11
                     /translation="MTWARQAGSSRPAEDKGWLAGVKAEERERMVVRDGLAVRTVAGHC
                     KDAEECAELLAMLGLDAADGRRPTVE"
     gene            complement(5458..6057)
                     /locus_tag="KOI47_RS05935"
     CDS             complement(5458..6057)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021511.5"
                     /locus_tag="KOI47_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2238 domain-containing protein"
                     /protein_id="WP_216214654.1"
                     /transl_table=11
                     /translation="MREPAVLLTVALAGLVVSGTGAHDIGTWLLEVTPIAIAVPVLAAT
                     FSRFRFTVLAYRLMTAGALMMELGAHYTYAHVPLGFWMQDWFGFARNHYDRLGHIMQGV
                     VAAIVLRELLLRHTGLRPGRWLWLVLTAGCLGISAGFELIEAAAATVSGQGGAYLATQG
                     DPMDTQWDMLMALLGALTCQALLSRAHDRQLQESRV"
     gene            6137..6544
                     /locus_tag="KOI47_RS05940"
     CDS             6137..6544
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005443880.1"
                     /locus_tag="KOI47_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_216214657.1"
                     /transl_table=11
                     /translation="MKHDQFIGRVQARARLASRGEAEGITRATLETLGERIPERVADHV
                     AAQLPIEIGEHLRRTVTMGGAGSGERFGIDEFAERVAERGHTTPPQAVYGSRVVLEVIG
                     EATEGVVEKVRDALPGELRGLIDAGSSGSLS"
     gene            complement(6537..6725)
                     /locus_tag="KOI47_RS05945"
     CDS             complement(6537..6725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686208.1"
                     /locus_tag="KOI47_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_216214659.1"
                     /transl_table=11
                     /translation="MAAQRGWVKSSRSSTGTNCVEIALPDDTHRDIGIRDTKNRAGGTL
                     LLSTRAWRAFTHAVRAS"
     gene            complement(6725..7576)
                     /locus_tag="KOI47_RS05950"
     CDS             complement(6725..7576)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010307705.1"
                     /locus_tag="KOI47_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_216214661.1"
                     /transl_table=11
                     /translation="MGGSTRTPKARALGAALAEARKERGLSQRDLAAKTGKSPGTIARW
                     ETGDRVPDPEDVAAVLTALEVSGERYADIHAMATGTREPRWLAVTLPEQRQQLNALLEC
                     GRTASTVTDVSPLLVPGVLQNSAYIRAIMEAGGVPRAEVETRIAVRVGRRELITRSEPA
                     EFVALLGEAALRQVIGSRETQAEQLRYLLELGELPNVHLRVLPFGSGWHPALEGPFVLI
                     DSTEDDPVVHLELRDTGLFLHEREDVARYRQAIDTITAVALHPEESAGLIAGIAAEMEG
                     AS"
     gene            7730..7963
                     /locus_tag="KOI47_RS05955"
     CDS             7730..7963
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216214663.1"
                     /transl_table=11
                     /translation="MNAPQWRSTRIAPARTPDGRATRVVLGLAAADGGHLVAIRVGDGE
                     PAHLARQGALELLASVREVIAEQDRLDGGGFR"
     gene            7960..8211
                     /locus_tag="KOI47_RS05960"
     CDS             7960..8211
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216214665.1"
                     /transl_table=11
                     /translation="MSDPLWMVRFRPGVVGERWRMVHLVPVPDPAAVPVTVGDCVRVLV
                     ALCGQQFAPGEAERLSRPAGAPCEVCLALLERASIEGG"
     gene            8217..8405
                     /locus_tag="KOI47_RS05965"
     CDS             8217..8405
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216214667.1"
                     /transl_table=11
                     /translation="MVSILVFVGACLVALAAGFWLGLLFTGRASGGGHRFHDPAVSVQA
                     TIARATADDRMRPEWRE"
     gene            complement(8576..8806)
                     /locus_tag="KOI47_RS05970"
     CDS             complement(8576..8806)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009157017.1"
                     /locus_tag="KOI47_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_216214669.1"
                     /transl_table=11
                     /translation="MKNNASSSDSTGMHGWRKSSYSGQNGCVELSGSAPGHIRVRDSKL
                     GADSPILVFDRHEIQAFLRGAKDGEFDHLVG"
     gene            complement(8803..9663)
                     /locus_tag="KOI47_RS05975"
     CDS             complement(8803..9663)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164759.1"
                     /locus_tag="KOI47_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5753 domain-containing protein"
                     /protein_id="WP_216214671.1"
                     /transl_table=11
                     /translation="MGTLNPTAIKRWIALEARRLREAAGYDRAAAAERIGKATTVIAHI
                     ETARNLPAPADLEILLDLYGVPDHVPLFRDMIKRAKRGQDWWIKFTSVPEYLTLYLGLE
                     TGAARISSVDLHIVPGLFQTRDYAFAILGPPGQRMSDEEIAARVDLRMARQELLNRSEN
                     PPQVWSVLDEGALRRQVGGPAVMRDQLRHLAQLTEQPNIEIQVLPFTAGTHPATDGTFT
                     ILDYPPEFVGDPGTVYIENRRGGLYYETTEELRDFRNVFERLQIQAEKPERSREFILNL
                     SKEIS"
     misc_feature    complement(9773..9787)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.65"
                     /tool="antismash"
     aSDomain        10001..10267
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KOI47_RS05980_Pantocin_Microcin_RRE.1
                     "
                     /evalue="4.00E-21"
                     /identifier="RREFam017.1"
                     /label="KOI47_RS05980"
                     /locus_tag="KOI47_RS05980"
                     /protein_end="89"
                     /protein_start="0"
                     /score="66.0"
                     /tool="antismash"
                     /translation="MRPRIKAEHCPARFGDGWLRIGGKVFGIAADLRDPDGAVWALLEL
                     LDGTRTVDQVIADLVHRFPGRAAGEIRADIEQLSELGYVEDADE"
     gene            10001..11101
                     /locus_tag="KOI47_RS05980"
     CDS             10001..11101
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635656.1"
                     /locus_tag="KOI47_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_216214673.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1e-18,
                     bitscore: 66.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.7e-47, bitscore: 160.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPRIKAEHCPARFGDGWLRIGGKVFGIAADLRDPDGAVWALLEL
                     LDGTRTVDQVIADLVHRFPGRAAGEIRADIEQLSELGYVEDADEPACTALSSRQRERYE
                     RGRLLNRWVDRTPRGSSWDFQIRLSRARVVVVGLGGVGCTAALALAQSGVGRLHCVDHD
                     VVELSNLNRQVLYGERDLGQPKAEVAVAKLRAVNSDIEVTGEPTRIEHPAALRSLAAAC
                     DVLVMSADQPAELWSWANRACARTRTAWVHGAYRGPQADMGLYRPGAGPCYECARAADQ
                     DRAALRPPVAEWRAVPMGPRVHAANAVTAGMVGNLVAHAVLSLLTGSPRLRVNCQYGFN
                     LVTLDHNFVTVLDRSHPECRTCAVAS"
     gene            complement(11133..12002)
                     /locus_tag="KOI47_RS05985"
     CDS             complement(11133..12002)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670468.1"
                     /locus_tag="KOI47_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_216214675.1"
                     /transl_table=11
                     /translation="MPRRPGTDHARLAAKLREIRAATGMSGNRFARHLGWPQSRVSKIE
                     TGTQLPTDADITAWLRAAEASGEEDAVTELLTRARVESVSFRHAYREVGGAGAQQRSYR
                     DRDQQASRIATFQPSMVPGLLQTPAYARDVIFLPASPVRLGHSTPEDAERMVSVRIERQ
                     SLLYDPDRTLLFVLGEAALWTRMGSLETHLGQLDRLQSVVGLRTIDVCILPFTAVMPLA
                     PPLGFIIYDNGYVMVETPTGEHLLRDPEEIRSYELIFDHLRAESVSGDAAVELIQGVSR
                     RLTTGPEP"
     gene            12139..12450
                     /locus_tag="KOI47_RS05990"
     CDS             12139..12450
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216214677.1"
                     /transl_table=11
                     /translation="MCAPAAPVAADSPWPEWCRIEEGNPMFAAWIQIAELALLPLGLGV
                     GYVAGRVSRREEQVACRPENTITHPGLAPEYPARHGHTAPYPPTTWDSSRVPGHGPMR"
     gene            complement(12472..13269)
                     /locus_tag="KOI47_RS05995"
     CDS             complement(12472..13269)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643747.1"
                     /locus_tag="KOI47_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_216214679.1"
                     /transl_table=11
                     /translation="MGSSSDVPALRRGLAVLRVLGAHAGPVSAATVARELDLPRSTTYH
                     LLSELEAAGFVAHLPAERRYGLGIAVFELGSAYLRHEPLERLATPLLRKLVDRTGHNAH
                     LGVLHGNESLYLIKERPAQPETLVTDVGVRLPGQLTASGLAILMHLSKPHVRALFPAAT
                     AFVDRTGRGPRGLAELRRVLSTHRRRGWAVEDGQVTAGFASVASPVFDHGGRPLAAISV
                     TFRHHCEDGPCGQDWPELATEVRHTAAELTSRIGGRPGDAAPE"
     gene            complement(13337..13642)
                     /locus_tag="KOI47_RS06000"
     CDS             complement(13337..13642)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026057.1"
                     /locus_tag="KOI47_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_232376564.1"
                     /transl_table=11
                     /translation="MTTMQGAKAGTVRLVVFAGAAALIFVASVPFGYGPLVVGLAVLGA
                     GFVVRRRDPALARLAQILGAIMTALGLAIVLTSLAASSGPVDKAPPVPQEVPVQRP"
     misc_feature    13771..13788
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(13801..13816)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    14041..14051
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            14535..16082
                     /gene="hutH"
                     /locus_tag="KOI47_RS06005"
     CDS             14535..16082
                     /EC_number="4.3.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004397 - histidine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006548 - L-histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hutH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667867.1"
                     /locus_tag="KOI47_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine ammonia-lyase"
                     /protein_id="WP_216214681.1"
                     /transl_table=11
                     /translation="MPEAVELGERPLRPDQAVAVARGQATVGFSELAERKMAESRRHVE
                     TLAGAQQPTYGVSTGFGALAVRHIPPESRTQLQRSFVRSHAAGAGEPVEPEVVRALMVL
                     RLRTLVTGHTGVQPATAHALAGLLNAGITPVVHEYGSLGCSGDLAPLAAVALALTGEGE
                     VFDAAGTRMPAAEALRAAGIEPVTLAEKEGLALTNGTDGMLGMLLLAAADLHRLLDIAD
                     LTAAMSVEALLGTDRAFAEDLQALRPHPGQAISGARMRAALADSPIVASHRGPDCTRVQ
                     DAYSLRCAPQVHGAARDTLDHAELVAERELAAAIDNPVVLADGRVESNGNFHGAPVAYA
                     LDFLAIPAADVAGIAERRTDRMLDVARSHGLPAFLAADPGVDSGHMIAQYTQAAVVSEL
                     KRLAAPASVDSIPSSAMQEDHVSMGWSAARKLRRAVEGLTTVLAVELLTAARALDLRAP
                     LLPAPVTGAVRDLLRTRVDGPGPDRHLAPEIAAAEDLIRTGAVLDAVTEHLPNGGTR"
     gene            16079..17731
                     /gene="hutU"
                     /locus_tag="KOI47_RS06010"
     CDS             16079..17731
                     /EC_number="4.2.1.49"
                     /GO_function="GO:0016153 - urocanate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006548 - L-histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hutU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005168430.1"
                     /locus_tag="KOI47_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="urocanate hydratase"
                     /protein_id="WP_216214682.1"
                     /transl_table=11
                     /translation="MSRTIRAARGGTLTARNWQSEGALRMLHNNLDPEVAERPEDLVVY
                     GGTGKAARDWSSFDAISRCLTTLAEDETLLVQSGKPVGVLRTHEWAPRVLIANSNLVGD
                     WATWPEFRRLDALGLTMYGQMTAGSWIYIGTQGILQGTYETFAAVAEKRFGGSLAGTLT
                     VTAGLGGMGGAQPLAVTMNDGAALVIECDPHRARRRMETRYLDELASDVDDAVRRVSAA
                     RAERRALSVGVIGNAAEVLPELLRRGVEVDIVTDQTSAHDPLAYLPKGVAVEDWDDYAA
                     KKPDEFTDRARDSMAEHVDAMLGFLDAGAEVFDYGNSLRGEAKLGGCERAFDFPGFVPA
                     YIRPLFCEGKGPFRWAALSGDPADIAATDRAILDLFPENESLARWIRLAGERVSFQGLP
                     ARICWLGYGERHLAGLRFNEMVARGELSAPVAIGRDHLDAGSVASPYRETEGMADGSDA
                     IADWPLLNALVNTASGASWVSIHHGGGVGMGRSIHAGQVCVADGTTLAGQKIERVLTND
                     PGMGVLRHVDAGYERAAEVASERGVRVPMMEAE"
     gene            17818..19017
                     /locus_tag="KOI47_RS06015"
     CDS             17818..19017
                     /GO_function="GO:0016813 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amidines
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331658.1"
                     /locus_tag="KOI47_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoate amidohydrolase"
                     /protein_id="WP_216214684.1"
                     /transl_table=11
                     /translation="MSTQGLLDQLSDVGRDRRRGGYSRHAFDPAELELRTWFTEQASRR
                     GLDVETDRNGNLWAWWGSPGQDALVTGSHLDSVPGGGAFDGPLGVVSAFTAVDALRERG
                     RPPRRPFAVVAFAEEEGGRFGVPCLGSRLLTGAISAETARALKDPDGITLAEAAAGAGL
                     DPERIGADPDRLATIGQFVELHVEQGKGLSYDNHSLAIGTDISAHGRWRFTFTGQGDHA
                     GTTLLMHRKDPMLPAAATVGATRIAAMDASHGRATVGRLVPNPGGTNVIASSVDLWLDA
                     RAEDEYCTRAMVEEIAEAARSAAEQEGCTLQITEESYSDTVYFDRGLGQELGRVLGRVP
                     AIPTGAGHDAGILAPHLPTGMLFVRNPTGISHAPEEFAEPEDVERGAAALADVLEHLGS
                     "
     gene            19014..20315
                     /locus_tag="KOI47_RS06020"
     CDS             19014..20315
                     /EC_number="3.5.3.13"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331659.1"
                     /locus_tag="KOI47_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="formimidoylglutamate deiminase"
                     /protein_id="WP_216214685.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4e-41, bitscore:
                     140.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMYWCEYAWLPDGVAEGVRIEVSGDRIASVQRDLPRAGTILNGL
                     TLPGFANTHSHAFHRALRGRTHHERGTFWSWRERMYELAERLDPDSYYRLARAVYAEMV
                     LAGYTSVGEFHYLHHAPGGIAYAEPNVMSQALAAAATDAGIRLTLLDTCYLAGGFGQPP
                     SRHQSRFADADATAWAERARAFTPAGELVRRGTAVHSVRAVPAEQLPTVAEAAEGLPLH
                     VHLSEQRGENVDCLAQHGRTPTTLLSECGVLGPHTVAVHATHLTSTDIGALSRTGTRAC
                     FCPTTERDLGDGIGPARALLDAGVGLCLGSDSHAVVDAFEETRALELNERLSSEERGRI
                     EVGELMAAATGHDAIGWSEVGELAPGAGADLVTVDLDSVRTAGIEPSGALYAAGAADVR
                     EVMIAGRWVVQDRGHKLLPHPAAALAREIGQLWE"
     misc_feature    complement(20448..20463)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.83"
                     /tool="antismash"
ORIGIN
        1 tcagggagct ggaggtgccg aggcggcagc cggagcgcca gccggggctg tcctcggtat
       61 accagccggt cccgttcgag caggacgcca gcatcctgat ggtcggggag cggaccaacg
      121 ccaacggctc caaggcgttc cgcacggcca tgctggagga gcgctactcc gactgcgtgg
      181 agatcgccaa gtcgcagacc cgcgagggcg cgcacgtgct ggacctgtgc gtggactacg
      241 tcggcaggga cggcacgcat gacatgcggg agctggcggg catgctggcc accgcgtcca
      301 cgctgccggt catggtcgac tccaccgagc cggacgtgct cgaggtcggc ctggaacacc
      361 ttggtggccg gtgcgcgatc aactcggtga actacgagga cggcaccgag ccgggcgggc
      421 gctacgacaa ggtcatgcgg atggccgttg agcacggcgc cgccgtcgtg ctgacctgta
      481 tcgacgagga gggtcaggcc cggaccgcgg agtggaagct gcgggtcgcc gagcgggcga
      541 tcaccgactt caccgagaac tggggcctgg agaagtccgc gatcatcgtg gactgcctgg
      601 tcttcccgat caccaccggg caggaggagg tccgcaagga cggcatcgag acgatcaacg
      661 cgatccgcga gctcaagcgg cggcaccccg aggtgcagac cacccttggt ctgtccaatg
      721 tgtccttcgg gttgaacccg gcggcgcggc aggtgctgaa ctcggtgttc ctgcacgaat
      781 gccaggaggc cgggctggac tcggcgatcg tgaactcctc gaagatcctg ccgatgaaca
      841 agatcgagga ggagccgcgc caggtcgcgc tggacctggt ctacgaccgg cgcagcgagg
      901 gttacgaccc gctgcagaag ctgatgcagc tgttcgaggg caagaccgcg tcctcgagca
      961 gtgcctcgcg ggccgaggag ctggcgaagc ttccgctgtt cgagcggctg gagcggcgga
     1021 tcgtcgacgg cgagcgcaac gggctggacg aggatctgga ggcggcacgg caggagaaga
     1081 agccgctgca gatcatcaac gagaacctgc tcgccgggat gaaggtcgtc ggtgacctgt
     1141 tcggttccgg gcagatgcag ctgccgttcg tgctccagtc ggccgaggtg atgaaggccg
     1201 cggtggccta cctcgagccg tacatggaga aggacgactc cggcggcaag ggcaagctgc
     1261 tgctggccac ggtcaagggc gatgtgcacg acatcggcaa gaaccttgtc gacatcatcg
     1321 tgtccaacaa cggctacgac gtggtcaaca tcgggatcaa gcagccgatc aacgtgatcc
     1381 tggacgccgc cgaggagcac aaggtggacg ccatcggcat gtccggactg ctggtcaagt
     1441 cgacggtgat catgaaggac aacctgatcg agatgaactc tcggggggtt gccgagaagt
     1501 acccggttct gctcggtggt gcggcgttga caaggacgtt cgtggagaac gaccttgacg
     1561 aggtctacca gggtgacgtc cgctacgcca aggacgcctt cgaggggctc aacctgatgg
     1621 accggctgat ggccatcaag cgcggggacg ccccggagga ggacgaggcg gagcaggcca
     1681 agaaggccga gcgcaaggca cgccgcgagc ggtcgctgcg gatcgccgag aagcgcaagg
     1741 ccgagcaggg cgacgagccg agcctggacg acaccacccg ctccgatgtg gccgccgatc
     1801 tcccggttcc ggtgccgccg ttctggggat cgaaggtcat caaggggatc gccacagccg
     1861 actatctgtc ccttttggac gaacgagcga cgttcttcgg tcagtggggc ctgcggggcg
     1921 ccaagaaggg cgagggaccc tcctatgagg agctcgtcga gaccgagggc aggccgcggc
     1981 tgcgggcgtg gatggacgag ctgtccaccg cgggcatcct gcagcatgcc gcgctggtgt
     2041 acgggtactt cccgtgctac tccgacggca acgacctgat cgtgctggac aaggaggagc
     2101 cggacgcgcc ggagcggcta cggttccact tcccgcgcca gcgcagggac cggcggctgt
     2161 gcctcgccga cttcttccgc tccaaggaga aggccgagga gaccggccag gtcgatgtgc
     2221 tgccgatgca gctggtcacg atgggccagc cgatcgcgga ctacgccaac gatctgttcg
     2281 ccaagaactc ctaccgggac tatctggaga tccacgggct cggcgtgcag ctcaccgagg
     2341 cgcttgccga gtactggcac cgcagggtcc ggcaggagct gctgttccca tccggaacct
     2401 cggtggcggc tgaggacccc gaggaggtcg agcagtactt caagctcggc taccggggcg
     2461 cccggttctc cttcggttac ggggcctgcc cggatatcga ggaccgggcg aagatcgtcg
     2521 acctgctgga gccggaccgg atcggtgtgg agctgtccga ggagttccag ctgcatcccg
     2581 agcagtccac cgacgccctc gtgctgcacc acccggaagc gaagtacttc aacacctgag
     2641 aaagacaaga aagggagtca tgagcgagaa gttccagaag gtgggcggcc tcgagttcgc
     2701 cgtcgccgac ctgtcgctgg ccgaggccgg ccggcaccag atccggctcg ccgagcacga
     2761 gatgcccggc ctgatggcca ctcgcaagga gtacgcggat tccaagccgc tcaagggcgc
     2821 gcggatcgcc ggttcgctgc acatgacggt gcagacggcg gtgctgatcg agacgctggt
     2881 cgagctcggt gccgaggtgc gctgggtttc ctgcaacatc ttctccaccc aggacgaggc
     2941 cgcggccgcc gtcgtggtcg gcccgaacgg caccccggcc aagccggagg gcgtctcggt
     3001 gttcgcctgg aagggcgaga cgctcgagga gtactggtgg tgcaccaacc agctgttcca
     3061 gttcggtgac aagggcccga acatgctgct ggacgacggc ggcgacgcca ccctgctggt
     3121 gcacaagggc gtggagttcg aggccgcggg cgcggttccg gagaccgacg cgaacgaccc
     3181 ggacgagtac aaggtcgtcc tggccacgct gcgcaagagc ctcgccgagg acaccaagcg
     3241 gttcaccagg atcgccgagg gcatcaaggg tgtcaccgag gagaccacca ccggcgtgca
     3301 ccggctgtac gagttcgcca agtcgggcga gctgctgttc ccggcgatca acgtgaacga
     3361 ctcggtcacc aagtcgaagt tcgacaacaa gtacggctgc cggcactccc ttgtggacgg
     3421 catcaaccgg gcgaccgaca cgctgatcgc gggcaaggtc gccgtcatcg ccggttacgg
     3481 cgacgtcggc aagggctcgg ccgagtcgct gcgcggccag ggcgcgcggg tgatcatcac
     3541 cgagatcgac ccgatctgcg cgctgcaggc ggcgatggag ggctacgagg tcaccacgat
     3601 ggacgaggtc gtcgacaagg ccgacatctt cgtcaccacg accggcaact tcgacatcat
     3661 caccgccgag cacatgtcga agatgaagca ccaggcgatc gtgggcaaca tcggccactt
     3721 cgacaacgag atcgacatgg cgggcctgga gaagatcccc ggcatcaaga aggtcgagat
     3781 caagccgcag gtgcatgagt acgtgttccc ggacggccac tcgatcatcg tgctgtccga
     3841 gggcaggctg ctcaacctcg gcaacgccac cggccacccg agcttcgtga tgtcgaacag
     3901 cttcgccaac cagacgatcg cgcagatcga gctgttcacc aagaccgacg agtacgacaa
     3961 gcaggtctac gtgctgccca agcacctcga cgagaaggtg gccaggctgc acctggacgc
     4021 gctcggcgtg aagctgacca agctgaccaa ggagcaggcc gagtacatcg gcgtcgacgt
     4081 cgagggaccc tacaagcccg accactaccg ctactgatcg atcccgtgcg tccgcgtccg
     4141 gtgccgccag cgcgcggcac cggacgcgga ccacccgtcg ggaaacgcgg atacggcgag
     4201 agggagccat gaacacgatc gcactcgagc tggtaccgcc cgagatcgag ggtggcgagc
     4261 agcgggcggc cgaggaaggc cagaaggtag ccgagctctg ccgcgcgagc gggctgaccg
     4321 aggccatcca gcacgtgatg atccccggca tgatcgccga ggacgacgac cgcccggtcg
     4381 agatgaagcc caggatggac gtgctggact tctggaacgc actgcgcccc gagctgggtg
     4441 ccatgcgggg gctgtgcacg caggtcaccg cgttccacga caagcaggcg ctgacgtccc
     4501 ggctgaacga gctgcgtgac tcgggcatgg acgggatcat cttcgtcggc gtgccccgca
     4561 cgatgaacga cggcgacggc cccggcatgg ccccgaccga cgccctggcc gagttcaccg
     4621 gcgtggtccc gaaccggggc gtgatcctca ttccgacgcg ggacggcgag ctgggccggt
     4681 tcggcttcaa gtgcgaccag ggcgcgacct tcggcatgac ccagctgctc tactccgacg
     4741 cgatcgtcgg cttcctgcgc gatttcgcca aacagagcga gcatcggccg gagattctgc
     4801 tctcgttcgg cttcgttccc aaggtcgagc agcggatcag gctgatcgac tggctcatcc
     4861 aggatcccgg taacccggcg gtcaaggagg aacaggagtt cgtcgccaag ctggccgact
     4921 cgaccttcgc cgaacgcaag cacgaactgg tggagctgta caagcgggtg accgacggcg
     4981 tgcgcgagct ggggttcccg ctgagcattc acctcgaggc gccctacggc gtgagcaagc
     5041 ccgcctttga ggttttcggc gagatgctgg accactacag cccgctcgcg tcctgacgtt
     5101 ccagtagccc ggctgacccc cgatcaggtg atggtgcgac gatgggggtc cgcggagttc
     5161 cccggttccg cggaccccct cgtggcccga tacagcggca ccgtaccggg ccggaagaag
     5221 gtgccagatg acctgggcaa ggcaagctgg ttcgtcccga ccggccgagg acaagggctg
     5281 gttggcaggt gtgaaggccg aggaaagaga acgcatggtg gtccgcgacg ggctcgccgt
     5341 gcggaccgtg gccggtcact gcaaggacgc ggaggaatgc gccgagttgc tggccatgtt
     5401 gggcctcgac gcggcggacg gaaggcgccc caccgtggag tgaccggctg accggtctca
     5461 tacccggctc tcctgcaact gccggtcgtg cgctcggctg agcagtgcct ggcaggtgag
     5521 tgcgcccagc agtgccatca gcatgtccca ctgagtgtcc atcggatcac cctgggtcgc
     5581 gaggtaagcg ccgccctgcc cgctgacggt cgccgcggct gcctcgatca gctcgaaccc
     5641 ggcgctgatg ccgaggcagc ccgcggtgag caccagccac agccagcgcc ccggccgcag
     5701 cccggtgtgc cgcagcagca gttcacgcag cacgatcgcc gcgaccacgc cctgcatgat
     5761 gtggccgagg cggtcgtagt ggttgcgcgc gaacccgaac cagtcctgca tccagaagcc
     5821 cagcggcacg tgcgcgtagg tgtagtgcgc gccgagttcc atcatcagcg ctccggcggt
     5881 catcagccgg taggcgagca cggtgaaccg gaaccgggag aacgtcgcgg ccagcaccgg
     5941 caccgcgatc gcgatgggcg tgacttccag cagccaggtg ccgatgtcgt gtgcgccggt
     6001 tccggagacg accagcccgg ccagggccac tgtcaacagc acggcgggtt cccgcatacc
     6061 gggccgggta cccggccggg ccgcgtttag tcgccgcagc ggcaggcaac tccggcgggg
     6121 aggagaggag cgcgtcatga aacacgacca gttcatcggc cgggtgcagg cgcgggcccg
     6181 cctggccagc aggggcgaag cggaaggcat caccagggcg accctggaga cgctgggcga
     6241 gcggataccc gagcgggtcg ccgatcatgt cgccgcgcaa ctgcccatcg agatcggtga
     6301 acacctgcgc cgcacggtca ccatgggcgg cgccggatcc ggcgagcggt tcggcatcga
     6361 cgagttcgcc gagcgggtcg ccgaacgcgg gcacaccacg ccaccgcagg cggtctacgg
     6421 gtccagggtg gtgctcgagg tgatcggtga ggccaccgag ggcgtggtgg agaaggtccg
     6481 ggacgcgctg cccggcgagt tgcgcggcct gatcgacgcg ggcagttccg gctcgctcag
     6541 ctagcgcgca ccgcgtgggt gaacgcccgc caggctcggg tcgagagcaa cagggtgccg
     6601 cccgcgcggt tcttggtgtc ccggatgccg atgtcgcggt gtgtgtcgtc cggcagcgcg
     6661 atttccacgc agttggtgcc ggtgctgctc cggctggact tgacccaccc tcgctgtgct
     6721 gccatcagga tgctccttcc atctcggcgg cgatcccggc gatgagaccg gccgattcct
     6781 cggggtgcag ggccacggcg gtgatggtgt cgatggcttg ccggtagcga gcgacgtcct
     6841 cccgctcgtg caggaacagc ccggtgtccc gcagttccag atgcaccacc gggtcatcct
     6901 ctgtcgagtc gatcagcacg aaggggcctt cgagcgcggg atgccatccg ctgccgaacg
     6961 gcagcacccg caggtgcacg ttgggcagtt caccgagttc gagcaggtac ctgagctgct
     7021 cggcctgcgt ctcgcgggag ccgatcacct ggcgcagcgc cgcctcgccg agcagggcga
     7081 cgaactcggc tggctcggac ctggtgatca gttccctgcg gccgacccgg accgcgatcc
     7141 gggtctccac ctcggcgcgc ggcacgccgc ccgcctccat gatcgcccgg atgtacgcgc
     7201 tgttctgcag cacgccgggt accagcagcg gcgatacatc ggtcaccgtg ctcgcggtcc
     7261 gcccacactc cagcagggcg ttcagctgct gacgttgctc cggaagcgtg accgccagcc
     7321 agcgcggctc cctggttccc gtcgccatgg cgtggatatc cgcgtagcgc tcgccggaga
     7381 cctccagcgc ggtcagcacc gcggccacat cctccgggtc cggcacccgg tcgccggtct
     7441 cccagcgggc gatggtgccc gggctcttgc cggtcttggc cgcgaggtca cgctggctca
     7501 gcccgcgctc cttccgcgcc tcggcgagtg cggcgccgag cgcgcgagcc ttaggtgtcc
     7561 tcgtgcttcc acccacgcgg cacagcatat ggcacgtcag cggggttcat agcgtcaccc
     7621 gaaggaagca ttgcccgcct cgcttccaat tgcttccata ttactggaag cgacggaagc
     7681 ggaagtgtgc ggccgtcggc ctggaagcag cgtagcccgg agacccaccg tgaacgcacc
     7741 gcagtggcga agtacccgca tcgcgcccgc gcgtaccccc gacggcaggg ccacccgcgt
     7801 cgtgctcggt ctcgccgccg cggacggcgg ccatctggtg gcgatccggg tcggtgacgg
     7861 cgagccggcg cacctcgctc gtcagggcgc gctggagctg ctggccagcg tgcgcgaggt
     7921 catcgcggag caggatcggc tggacggggg cgggttccga tgagcgatcc actgtggatg
     7981 gttcggttcc ggcccggggt ggtcggggag cgctggcgga tggtgcacct ggttccggta
     8041 cccgatcccg cggccgtccc ggtcaccgtc ggcgactgtg tgcgggtgct ggtggccttg
     8101 tgcggccagc agttcgcgcc cggggaggcc gagcggctgt cccggcctgc cggcgccccg
     8161 tgcgaggtgt gcctcgcgct gctcgagcgg gcctccatcg agggcgggtg agcgggatgg
     8221 tgtcgatcct ggttttcgtc ggtgcgtgcc tggtcgccct ggcggccggg ttctggcttg
     8281 gcctgctgtt caccggccgg gcttcgggcg gcggtcaccg cttccatgac ccggcggtgt
     8341 cggtacaggc gacgatcgcc agggccaccg ccgacgatcg tatgcgtcct gagtggaggg
     8401 aatgatcgaa gtgcggcggg tactgcttcc tcgtgctgag caagggcgcg gtgcggcggc
     8461 tcgtgccgtt gctcgcccgc cccggccgga aaccggccgg ggcggtgttc gaatgctggc
     8521 ccgtggaggt cagccggatg ccgtcggatc cgacggcatc accctgtaca gccggttacc
     8581 cgaccagatg gtcgaactca ccgtcctttg cgccgcgcag gaaagcctgg atctcgtgcc
     8641 ggtcgaagac gaggatcggg ctgtccgcac cgagtttcga gtcgcgaact cggatgtggc
     8701 cgggtgcgga gccgctgagt tcgacgcatc cgttctgccc gctgtagctc gatttccgcc
     8761 agccgtgcat gccggtggag tcggacgagg atgcgttatt tttcatgaaa tctccttcga
     8821 cagattgagg atgaactctc gtgaccgctc gggcttctcg gcctggatct gcaggcgctc
     8881 gaaaacgtta cggaagtcgc gtagttcctc ggtggtctcg tagtagaggc caccgcgccg
     8941 attttcgatg tagacggttc cggggtcgcc gacaaactcg ggaggataat cgagaatcgt
     9001 aaaggtgcca tcggtggccg gatgggtgcc tgcggtgaag ggaagcacct ggatttcgat
     9061 gttcggctgc tcggtcagtt gagcaaggtg ccgcagctgg tcccgcatca ccgcgggtcc
     9121 gccaacctgg cggcgcagcg ctccctcgtc gagtaccgac cagacctgcg gtgggttctc
     9181 actccggttc agcagttcct gtcgcgccat tcgcaggtcg accctggccg cgatctcctc
     9241 gtcgctcatc cgctgccccg gcggtcccag gatggcgaaa gcgtagtccc gggtctggaa
     9301 aaggccgggc acgatatgca ggtccacgct gctgattcgc gcggcgccgg tttccaggcc
     9361 gaggtacagg gtgagatact ccggtaccga agtgaacttg atccaccagt cctgaccgcg
     9421 cttcgccctt ttgatcatgt cccggaacag cggcacatgg tccgggaccc cgtagaggtc
     9481 gagcaggatc tccaggtctg ccggtgcggg caggttccga gcggtttcga tatgggcgat
     9541 gaccgtggtg gccttgccga tgcgctcggc cgcggccgcc cggtcgtacc cggcggcctc
     9601 ccggagcctc cgtgcctcga gcgcgatcca gcgcttgatg gcggtcgggt tcagcgtgcc
     9661 cacggactcg ccacctcctc cggtttctca cggacggtca cagttgggtt cacccgcacg
     9721 gcctatcggc gaagcataga cgaccacaat gtgaatctct acatttgggg tacctgctaa
     9781 ttgagaactc tacattgtag agagggggct cggctggcgg gtgcgcccgc accagggcgg
     9841 ccggctgtgg ccgggatacc gaaccgggct tgcccgacgg tttcccggcc cccgtgaaag
     9901 gaggtggacg gcgatgatcg agatcgtgat ggtcggccgc gaggacgcgg tcgagcacat
     9961 ctactgcggc tcaggaggca actgagtaaa gggagttcgc atgcgtccac gtatcaaggc
    10021 agagcactgc ccggcccggt tcggcgacgg ctggttgcgc atcgggggaa aggtgttcgg
    10081 catcgccgcc gacctgcggg acccggacgg cgccgtgtgg gcgttgctgg aactcctcga
    10141 cgggacacgc acggtggacc aggtgatcgc cgacctggtc caccgcttcc ccggccgcgc
    10201 ggccggggag attcgggcgg atatcgagca actgagcgag ctggggtacg tcgaggacgc
    10261 cgacgagccg gcctgtaccg cgctgagcag caggcagcgg gagcgttacg aacgcggcag
    10321 gctgctgaac cggtgggtcg accgcacccc gcggggctcc agctgggact tccagatccg
    10381 gctttcgcgg gctcgggtgg tggtcgtcgg cctcggcggg gtgggttgca ccgcggcgct
    10441 ggcccttgcc cagtcggggg tcggccggct gcactgtgtt gatcacgacg tcgtcgaact
    10501 gtcgaacctc aaccgccagg tcctctacgg cgagcgggac ctggggcagc cgaaggcgga
    10561 agtggcggtg gcgaaactgc gcgccgtcaa ctccgatatc gaggtcacgg gggagccaac
    10621 gcgaatcgag cacccggccg cgctacggtc gctggccgcc gcctgcgacg tccttgtgat
    10681 gagtgccgac cagcctgccg agctgtggag ctgggcgaac cgggcctgcg cccggactcg
    10741 tacggcctgg gtgcacgggg cgtaccgcgg tccccaggcg gatatgggcc tgtaccggcc
    10801 gggcgccggt ccgtgctacg aatgcgcccg cgccgccgac caggatcgcg cggccctgcg
    10861 gccgccggtg gcggagtggc gggccgtgcc gatggggccg agggtgcacg ccgcgaacgc
    10921 ggtgacggcc gggatggtcg gcaacctggt cgcgcacgcg gtgctgagcc tgctcaccgg
    10981 ttcgccccgg ttgcgggtga actgccagta cggtttcaac ctggtcaccc ttgaccacaa
    11041 cttcgtgacg gtactggacc ggtcgcatcc ggagtgccgg acctgtgcgg tggcgtcctg
    11101 agcggctgcg gcacccgccc ggcatgctcc ggtcagggct cgggcccggt ggtcagccgt
    11161 cgcgaaacgc cctggatcag ctccacggcc gcgtcaccgc tcacggactc ggcccgcagg
    11221 tggtcgaaga tgagctcgta gctcctgatc tcctcggggt ccctgagcag atgttcgccg
    11281 gtcggagtct ccaccatgac gtagccgttg tcgtagatga tgaacccgag cggcggggcg
    11341 agcggcatca cggcggtgaa cggcaggatg cacacgtcga tcgtgcgcag gccgacgacg
    11401 gactggaggc ggtccagctg cccgaggtgc gtctcgaggc ttcccatccg ggtccacagc
    11461 gccgcctccc cgagtacgaa aagcagggtc ctgtcagggt cgtagagcag cgactggcgc
    11521 tcgatgcgca cggacaccat ccgctcggca tcctccggag tggaatgccc cagccgtacg
    11581 gggctggcag gcaggaagat cacgtcccgc gcgtaggcgg gcgtctgcag cagccccggc
    11641 accatcgaag gctggaacgt ggcgatccgg ctggcttgct gatcccggtc ccggtaggac
    11701 cgctgctggg cgccggcccc gccgacttcc cggtaggcat ggcggaacga caccgactcc
    11761 accctggcgc gagtgagcag ttcggtgacg gcgtcctcct cgccggaggc ttctgccgcg
    11821 cgcagccacg ccgtgatgtc cgcatccgtc gggagctgcg tcccggtctc gatcttggac
    11881 acccgcgact gtggccagcc gaggtgcctg gcgaaccggt tgcccgacat gccggtcgcg
    11941 gcccggatct cccggagctt cgcggcaagc cgggcatggt cggtgccagg gcgacggggc
    12001 atgcgaacgg agccttcttc cacggttcag gtaccagctg atccacgcga ccctgcgatc
    12061 atgccatacc tgaccggcat agttgtcgaa tagtacacga atagacgatt cgtacgcgga
    12121 tagttcgaga ataacctggt gtgtgctcct gcggctccgg tcgccgcgga cagcccgtgg
    12181 ccggagtggt gccgcatcga ggaggggaat ccgatgttcg ccgcgtggat ccagatcgcc
    12241 gaactcgcac tgctgccgct gggcttggga gtcggatacg ttgccggccg tgtctcccgc
    12301 cgggaggagc aggttgcctg ccgccccgag aacaccatca cccatcccgg cctcgcgccg
    12361 gagtacccgg cgcggcacgg gcacaccgcc ccgtacccac cgaccacatg ggactcgagc
    12421 cgggtacccg gacacggccc gatgcggtga ctcgccggcc gaggcccggg ttcactccgg
    12481 cgcggcgtcg cccggcctgc cgccgatccg gctggtcagc tcggccgcgg tgtgccggac
    12541 ctcggtggcg agctctggcc agtcctgccc gcaggggccg tcctcgcagt ggtgccggaa
    12601 ggtcacgctg atcgccgcca gcggcctgcc gccgtggtcg aaaaccgggg acgccaccga
    12661 ggcgaacccc gcggtgacct ggccgtcctc caccgcccag ccccggcggc ggtgcgtgct
    12721 cagtacccgc cgcagctcgg ccagcccgcg cggcccgcgc ccggtgcggt ccacgaaggc
    12781 cgtggccgcg gggaacaggg cccgcacatg gggtttggag aggtgcatca ggatggcgag
    12841 gccggaggcg gtgagctggc ccggcagtcg caccccgaca tcggtcacca gcgtctccgg
    12901 ctgggcaggg cgttccttga tcaggtacag cgactcgttg ccgtgcagca ccccgaggtg
    12961 cgcgttgtgg cccgtccggt cgaccagctt gcgcagcagc ggagtggcca gtcgctccag
    13021 cggctcgtgc cgcaggtacg ccgagccgag ctcgaacacc gcgattccca gcccgtatcg
    13081 ccgctccgcg ggcaggtgcg cgacgaaccc ggccgcctcc agttcgctga gcaggtggta
    13141 cgtggtcgag cggggcaggt ccagctccct ggccacggtg gcggcggaca ccggcccggc
    13201 gtgcgccccc agcacgcgca ggaccgcgag tccgcggcgc aacgccggaa cgtcgctact
    13261 cgatcccatc cgtgccctcc tgtctggtac cccagacgtg agggtaggac atccagcttg
    13321 gcggagactt gctgcttcag gggcgttgca ccgggacttc ctgtgggact ggtggagcct
    13381 tgtcgacagg acccgagctc gccgccaggc tggtcagcac gatcgccagc cccagcgccg
    13441 tcatgattgc gccgaggatc tgagccagcc tcgccagcgc cggatcccgg cgccggacga
    13501 cgaacccggc gccgagcacc gccaggccga cgaccaatgg tccgtagcca aaaggtacgg
    13561 atgccacgaa gatcaacgcg gcagcaccgg cgaatacgac cagccggaca gtgcccgcct
    13621 tggccccctg cattgtcgtc atgccaactc acctactcaa ctttccgccg gccaccttac
    13681 ggtttccgtt cgtcctccgc tgcgatttca gcacagagag gatgacgaac aagcctgccg
    13741 ctacctgcag tagcgatagc cagccagggt tatcgctttg agtggccaga tagacgcccg
    13801 tgaggactac gccaatcccc aggagaaggc ccaatcgacg ccgaacggga gattgccatg
    13861 gacctttgct caccgcaccc cctggctcga tgactttata gagcgtccgc cgctggtcag
    13921 actaactcgt gggtcagccg aggtcgacgc cgcgcagtcc ggttcgtgag atgacgtaga
    13981 gaaacgggcc ggggctggca caggcatcgg tgatcttgtc gagcacccga gatagagctg
    14041 cgccatgtca ctggcgcgga ggttgccgct ggtcaagcag aacgcacgta catgatggcg
    14101 gaccagggcg gcgcgctcgg cgggacggta gcacctcggc cagtgtctgc agccgcaacc
    14161 cggcgccagt cctggtcgcg atccgcacag cgtcaccgag ctggtcacgc ggcatgccgt
    14221 actcatcggc cacgacatcc atgggctcgc ccgcgcggaa gagcccgagt gcgtcgtcaa
    14281 ggcgcgtcgc cggcgaatac cggtctggcg ccggccgcga cctcgctgcc aattcaaccg
    14341 actgcacccc tgaccggccc cagagagttc gcgctcccgg ctcacgttcg ggaacggcca
    14401 actcgtgcgc gtggcgggca aacacgggta cgtggggagc aaacacgccg gggggctggc
    14461 ggatgtctgg tattccagac gagataccgc gcgccggggc tgcccagcgg gcgcgggcgg
    14521 ggtgaaatgg gggcatgcca gaagcagtgg aactgggcga gcggcccctg cgccccgatc
    14581 aggcggtggc cgtagcccgc gggcaggcga ccgtagggtt cagcgagctc gccgagcgga
    14641 agatggccga gtcccggcgg cacgtggaga ctctcgccgg ggcacagcag ccgacctacg
    14701 gggtgtccac cggattcggg gcgctggccg tacggcatat cccaccggag agccgcaccc
    14761 agctgcaacg ctccttcgtc cgctcgcacg cggccggggc cggcgagccg gtggagccgg
    14821 aggtggtgcg cgcgctgatg gtgttgcggc tgcgcaccct ggtcaccggg cacaccggcg
    14881 tccagcccgc gaccgcgcac gcgctggccg ggctgttgaa cgcgggcatc accccggtgg
    14941 tgcacgagta cggctcgctg ggctgctcgg gcgatctcgc cccgctggcc gcggtggcac
    15001 tcgcgctgac cggggagggc gaggtgttcg acgccgcagg cacccggatg cccgcggccg
    15061 aggcgctgcg cgccgccggg atcgagccgg tcacccttgc cgagaaggaa gggctcgcgc
    15121 tcaccaacgg caccgatggc atgctcggca tgctcctgct cgccgccgcc gacctgcacc
    15181 ggctgctgga catcgccgac ctcaccgcgg cgatgagcgt ggaggccctg ctcggcaccg
    15241 accgtgcctt cgccgaggac ctgcaagccc tgcgcccgca tccgggccag gcgatctccg
    15301 gggcccggat gcgcgccgca ctggccgact cgccgatcgt ggccagccac cgcggcccgg
    15361 actgcacccg ggtgcaggac gcctactcgc tgcgctgtgc gccccaggtg cacggcgccg
    15421 ccagggacac cctggaccac gccgaactcg tcgccgaacg cgaactcgcc gccgccatcg
    15481 acaacccggt ggtgctcgcc gacgggcggg tggagtccaa cggcaacttc cacggcgccc
    15541 cggtggccta tgccctggac ttcctcgcca tcccggcagc cgatgtggcc ggcatcgccg
    15601 agcgacgcac cgaccggatg ctggacgtgg cccgctcgca cggcctgccc gccttcctcg
    15661 ccgccgaccc cggggtggac tccgggcaca tgatcgccca gtacacccag gccgccgtgg
    15721 tcagcgagct gaagcggctg gccgccccgg cctcggtgga ctccatcccg agcagcgcca
    15781 tgcaggagga ccacgtgtcc atgggctggt cggcggcccg caagctgcgc cgcgccgtcg
    15841 aggggctcac cacggtgctc gcggtcgaac tgctcaccgc cgcccgcgcg ctggacctgc
    15901 gcgccccgct gctgcccgca ccggtcaccg gggccgtgcg cgacctgctg cgcacccggg
    15961 tcgatggtcc cggcccggac cgccacctcg cgccggagat cgccgcggcc gaggacctga
    16021 tccgtaccgg cgccgtactg gatgccgtga ccgagcacct gccgaacgga ggtacccgat
    16081 gagccgaacg atccgggcgg cccgcggggg cacgctgacc gcgcgcaact ggcagtccga
    16141 gggcgccctg cgcatgctgc acaacaacct ggatcccgag gtcgccgagc gacccgagga
    16201 cctggtggtc tacggcggca cggggaaggc cgcgcgggac tggagcagtt tcgacgcgat
    16261 cagccgctgc ctcaccaccc tggccgagga cgagaccctg ctggtgcagt ccggcaagcc
    16321 ggtcggggtg ctgcgcaccc acgagtgggc gccgcgggtg ctgatcgcca actccaacct
    16381 ggtcggggac tgggcaacct ggccggagtt ccgcaggctg gacgcgctcg ggctgaccat
    16441 gtacggccag atgaccgcgg gttcctggat ctacatcggc acccagggca tcctgcaggg
    16501 cacctacgag accttcgccg ccgtggcgga gaaacgattc ggcggcagcc tggcaggtac
    16561 gctcaccgtc accgccggtc ttggcggtat gggtggcgcg caaccgcttg cggtgaccat
    16621 gaacgacggc gccgcgctgg tgatcgaatg cgacccgcac cgggcacgtc gtcgcatgga
    16681 gacccgctac ctcgacgaac tcgcgtccga tgtggacgac gccgtgcgca gggtgagcgc
    16741 ggcgcgcgcg gaacgcaggg cgctgtcggt cggggtgatc ggcaacgccg ccgaggtgct
    16801 gcccgagctg ctgcgccgcg gggtcgaggt ggatatcgtc accgaccaga cctcggcgca
    16861 cgacccgctg gcctacctgc caaagggggt ggcggtagag gactgggacg actacgcggc
    16921 gaagaagccg gacgagttca ccgaccgcgc gagggactcc atggccgagc acgtggacgc
    16981 catgctcggg ttccttgacg ccggagcgga ggtcttcgac tacggcaact cgctgcgcgg
    17041 cgaggccaag ctcggcggtt gcgagcgggc cttcgacttc cccgggttcg tgcccgccta
    17101 catccgcccg ctgttctgcg agggcaaggg gccgttccgc tgggccgcgc tgtccgggga
    17161 cccggccgat atcgcggcaa ccgaccgggc gatccttgat ctcttcccgg agaacgagtc
    17221 cctggcccgc tggatccggc tggccgggga gcgggtctcc ttccagggcc tgcccgcgcg
    17281 gatctgctgg ctcggctacg gcgagcggca cctcgcgggc ctgcggttca acgagatggt
    17341 ggcgcgcggt gagctgagtg ccccggtggc catcgggcgc gaccacctcg acgccggtag
    17401 tgtcgcctcc ccgtaccggg aaaccgaggg catggccgat ggctcggacg cgatcgccga
    17461 ctggccgctg ctgaacgcgc tggtcaacac ggcgtccggg gccagctggg tgtccatcca
    17521 tcacgggggt ggcgtcggta tgggacgctc gatccacgcc gggcaggtgt gcgtggccga
    17581 cggcaccacg ctggccgggc agaagatcga gcgggtgctg accaacgacc ctggtatggg
    17641 cgtgctgcgg cacgtcgatg ccggctacga gcgggccgcc gaggtcgcct ccgagcgtgg
    17701 ggtccgggtg ccgatgatgg aggcggagtg acagggcgtc cgaaaccggc gcggaatcgc
    17761 gacagcgggc agcggtacgc gcgttcggcg gagcccgcga gcggatccag acaagcagtg
    17821 agtacgcagg ggttgctgga ccagctgtcc gacgtcggca gggaccggcg tcgcggcggt
    17881 tactcgcggc acgccttcga cccggccgag ctggagctgc gcacctggtt caccgagcag
    17941 gcgagcaggc gcgggctgga cgtggagacc gaccgcaacg gcaacctctg ggcctggtgg
    18001 ggcagccccg gccaggacgc gctggtcacc ggcagccacc tggactcggt ccccggcggc
    18061 ggggccttcg acgggccgct cggcgtggtc agcgccttca ccgcggtgga cgccctgcgc
    18121 gagcggggcc gcccgccacg gcggccgttc gcggtggtcg ccttcgccga ggaggagggc
    18181 ggccggttcg gcgtgccctg tctgggatcg cgcctgctca ccggggcgat cagcgccgaa
    18241 accgcccgtg ccctcaagga tccggacggg atcaccctgg ccgaggccgc tgcgggcgcc
    18301 gggctggacc cggaacgcat cggtgccgac ccggaccggc tggccaccat cgggcagttc
    18361 gttgagctgc acgtggagca gggcaagggg ctgagctacg acaaccactc gctggcgatc
    18421 ggcaccgaca tcagcgcgca cggccgctgg cgcttcacct tcaccgggca gggggaccat
    18481 gccgggacca ccctgctgat gcatcgcaag gaccccatgc tgcccgcggc tgcgacggtc
    18541 ggcgcgacca ggatcgccgc gatggacgcc tcccatgggc gggccaccgt cggcaggctg
    18601 gtgccgaacc ccgggggcac caacgtgatc gcgtcctctg tggacctgtg gctggacgcg
    18661 cgggccgagg acgagtactg caccagggcg atggtcgagg agatcgccga ggccgcgcgg
    18721 tccgcggccg agcaggaggg ctgcaccctc cagatcaccg aggagtccta ctccgacacc
    18781 gtgtacttcg accggggact ggggcaggag ctcggccggg tactcggtag ggtgcccgcc
    18841 atccccaccg gtgccgggca cgacgcgggc atcctcgccc cgcatctgcc caccggcatg
    18901 ctcttcgtgc gcaacccgac cgggatcagc cacgcgcccg aggagttcgc cgaacccgag
    18961 gacgtggaac ggggcgctgc ggcgctggcc gatgtgctgg agcatctggg ctcatgacga
    19021 tgtactggtg cgagtacgcg tggctgccgg acggggtggc cgagggggta cggatcgagg
    19081 tctccgggga ccggatcgcc tcggtgcaac gggacctgcc aagggcgggc accatcctga
    19141 acggcttgac ccttcccggt ttcgccaata cgcactcgca cgcgttccac cgcgcgctgc
    19201 gcggccggac gcaccacgag cggggcacgt tctggagctg gcgcgagcgg atgtacgagc
    19261 tggccgagcg gctcgacccc gactcctact accggctggc ccgcgcggtg tacgcggaga
    19321 tggtactggc cggctacacc agcgtgggcg agttccacta cctgcaccac gcacccggcg
    19381 gcattgccta tgccgagccg aacgtgatga gccaggcact ggcggccgcg gccaccgacg
    19441 cgggcatccg gctgaccctg ctggacacct gctacctggc aggcgggttc ggccagccgc
    19501 cgagccgcca ccagtcccgg ttcgccgatg ccgacgccac ggcctgggcc gagcgggcca
    19561 gggccttcac cccggctggg gagctggtgc ggcgcgggac ggcggtgcac tcggtgcgcg
    19621 ccgtgcccgc cgagcaactg cccaccgtgg cggaggcggc cgaggggctg ccgctgcatg
    19681 tccacctttc cgagcagcgc ggggaaaacg tggactgcct cgcccagcac ggccggaccc
    19741 cgaccaccct gctttcggag tgcggggtac tcgggccgca taccgttgcc gtgcatgcca
    19801 cccacctgac cagcaccgac atcggcgcgc tgagccgcac cggcaccagg gcctgcttct
    19861 gcccgaccac cgagcgcgac ctcggcgacg ggatcggccc ggcgcgggcc ctgctggacg
    19921 ccggggtggg gctgtgtctc ggcagcgaca gccacgcggt ggtggacgcc ttcgaggaga
    19981 ccagggcgct ggagctgaac gagcggcttt ccagcgagga gcgcggccgg atcgaggtcg
    20041 gcgagctgat ggcggcggcg accggccacg acgcgatcgg ctggtccgag gtcggcgagc
    20101 tggctcccgg agcgggcgcg gacctggtca ccgtggacct ggactcggtg cgcaccgcgg
    20161 gcatcgagcc gagcggggcg ctgtacgcgg ccggggccgc cgatgtgcgc gaggtgatga
    20221 tcgcaggccg gtgggtggtg caggaccggg ggcacaagct gctcccgcac ccggcggccg
    20281 cgctggcgag ggagatcggg cagctgtggg aatgacggcg acactcctga ccgagatcgg
    20341 cgagctcacc accaacgacc ccgaactggg caggcgccgg gatgccgccc tggtgctgca
    20401 aggcgagcgg gtcgtatggg tgggggagcg ggccgccgcg ccgcccgccg acgagctggt
    20461 caacatggcc ggccgggcgg tgctgcccgg ctgggtggac agccacaccc acctggtgtt
    20521 cgctggtgac cgcaccgccg agttcgaggc gcggatggcg ggtgagccgt accgcgccgg
    20581 cgggatcgcg gtcaccgtgg aggccaccag ggccgcctcc gacgaggcgc tggcgcagaa
    20641 cctgcgcagc cacgtcgacg aggccgcgcg gcagggcacc acctgcctgg agaccaagac
    20701 cgggtacggg ctcaacgtgg ccgatgagca gcgcagcgcc cggatcgccg ccgaggtcgc
    20761 cgacgaggtg acctacctcg gtgcgcatct ggtcccgccc ggcgccgatc cggagtccta
    20821 tgtggacctg gctgccgggg agatgctcga cgccgtacgc ccgtacgtgc gctggggcga
    20881 cgtgttctgc gaggaagggg ccttcgacga ggcacagacc gggcggctgc tgctggcgat
    20941 ggccgggcac ggtctcggcc tgcgggtgca cggcaaccag ctcggtcccg ggcccggggt
    21001 ccagctcgcg gtgcggcacg gtgcggccag cgtggaccac tgcacctacc tgaccgaagc
    21061 cgatgtggac gcgctggccg gctcggacac cgtggccacc c
//
