LOCUS       NZ_CP036145            23535 bp    DNA     circular CON 25-JUN-2024
DEFINITION  Bacillus mycoides strain JAS94/5 chromosome, complete genome.
ACCESSION   NZ_CP036145
VERSION     NZ_CP036145.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5275222)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5275222)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 195.93x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018742285.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:27:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,786
            CDSs (total)                      :: 5,632
            Genes (coding)                    :: 5,433
            CDSs (with protein)               :: 5,433
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 199
            CDSs (without protein)            :: 199
            Pseudo Genes (ambiguous residues) :: 0 of 199
            Pseudo Genes (frameshifted)       :: 82 of 199
            Pseudo Genes (incomplete)         :: 133 of 199
            Pseudo Genes (internal stop)      :: 60 of 199
            Pseudo Genes (multiple problems)  :: 66 of 199
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:45:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1234136
            Orig. end                         :: 1257671
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036145.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13535](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            26..802
                     /gene="trpA"
                     /locus_tag="EXW57_RS06320"
                     /old_locus_tag="EXW57_06480"
     CDS             26..802
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016133917.1"
                     /locus_tag="EXW57_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06480"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_199626854.1"
                     /transl_table=11
                     /translation="MGVEKIIAAFENGKKAFIPYVMGGDGGLEKLKERIRFLDEAGASI
                     VEIGIPFSDPVADGPTIQRAGKRALDSGVTLKGIFQALIEVRQEVQIPFVLMTYLNPVL
                     AFGKERFIDSCLEAGVDGIIVPDLPYEEQDIIAPLLRVANIALIPLVTVTSPIERIEKI
                     TSESQGFVYAVTVAGVTGVRQNFKDEIRSYLEKVKAHVHLPVVAGFGISTREQIEEMIT
                     ICDGVVVGSKVIELLENEKREEICELIHAVKETEEA"
     misc_feature    complement(829..847)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            877..1227
                     /locus_tag="EXW57_RS06325"
                     /old_locus_tag="EXW57_06485"
     CDS             877..1227
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086916.1"
                     /locus_tag="EXW57_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06485"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_016126699.1"
                     /transl_table=11
                     /translation="MLRRKLLYLFLTVPLYAWLISMTKIELMALFLGYVFIFSQLNRIQ
                     EQSILEVCIFSISIELFSIVSIVLLSELFQWIHSFELIKLGNIVLQVICAYIVFVVLEK
                     MIGQQTVFQDKR"
     gene            1355..2854
                     /locus_tag="EXW57_RS06330"
                     /old_locus_tag="EXW57_06490"
     CDS             1355..2854
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168880.1"
                     /locus_tag="EXW57_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06490"
                     /product="L-lactate permease"
                     /protein_id="WP_003188030.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRASLISYAVSVGIVLLSPTF
                     QLGISETVHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPIFAYFIFLSLYVVGGWQAVIEKCKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSEQNFITEHAATAEREVSIIKIISP
                     YIFLTVCILLSRLVPVLHDFLRSYAVLDLKSYSYKLELLYSPGFWLAMTCLFTIIFFRI
                     PSNIIKQSLSQTIKQWIPFAITTTMFIAISELMGASGMHSLLAKTAGETFGTFFVFVAP
                     FIGGIGGFLTGSNAGSNAMFIKLQMQTAQNVAIPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVVVEVIVWYMLRK"
     gene            2946..3629
                     /locus_tag="EXW57_RS06335"
                     /old_locus_tag="EXW57_06495"
     CDS             2946..3629
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128607.1"
                     /locus_tag="EXW57_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06495"
                     /product="YukJ family protein"
                     /protein_id="WP_033730649.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVVQSKIGKGKTPHYQVHLQGEAGVNYRIAINVK
                     SQSYPSEVLYFASNNIRSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQMIPL
                     PAEKSGSDNDLNEKIEHYIKRAIDEKAIIYAFGERWGPEEKVPDSYFHFTPGNGIHDIH
                     MNQGNVEKWQGDDGKWQDGGILIHFEKKEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKRNN"
     gene            complement(3644..4477)
                     /locus_tag="EXW57_RS06340"
                     /old_locus_tag="EXW57_06500"
     CDS             complement(3644..4477)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="EXW57_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06500"
                     /product="hypothetical protein"
                     /protein_id="WP_078422197.1"
                     /transl_table=11
                     /translation="MEFVNSIFQTLLTSVIQLFSLIGVIIVIGFILGYLESLTRTYWSR
                     AFGRKGFLLTAWIGVPVHELGHAIMCLLFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     IYQRIGNFFIGIGPIISGITALILLMRYFVPDSYSLFNTNLEKTVTSTSISLDMIQNML
                     LSTFVLLKSLFTFSNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNQLIGKMMKYNMYFIAFSSVALLFSCISTLVSFVFYKIRRGRSL"
     gene            4678..5460
                     /locus_tag="EXW57_RS06345"
                     /old_locus_tag="EXW57_06505"
     CDS             4678..5460
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158836.1"
                     /locus_tag="EXW57_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06505"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_002126012.1"
                     /transl_table=11
                     /translation="MKCPACNTENAAEARFCGNCGHSLTEEVVASGGQEEGQLSRPARV
                     KETRPNETVEQVKQFASGYFQFFKNAFKSPSAIMESGNIEVRNGIVSLVLICFLGACIF
                     YRMMSAAATVTRTLVPDIATPTFFGESVMVFFFLLILTLFVGFIIFVSGKMMKSSFSFL
                     ESFGIWGTIATPAIAILVLSFLFSFLLIFFLPILLGLATTYMGISIIVAILKLDNGGVD
                     PVYTLIIANVLIGIATFIVFWSYIKTIIQTFIGGLTGF"
     gene            5480..6715
                     /locus_tag="EXW57_RS06350"
                     /old_locus_tag="EXW57_06510"
     CDS             5480..6715
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="EXW57_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06510"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_215566498.1"
                     /transl_table=11
                     /translation="MNVCTKCGAQYEDGVQFCQNCGMKRESLVVKKKMSGGTKVGITLL
                     TLLVIVIVGLYLYGSSYYKQTAQVDRMITILQERDGEKLAEIITADDPTVIVTRESLTP
                     LFSYIKENPFYVNELKEYLRQGEKQGDGIERADFSLTKDGKQFFLFDRYKLKAKTYYTT
                     LLTNEKGTSLKLNGKEIDKTNDKKFEKQYGPFLPGTQVFQSEYKNDYVKLSREEKVVLM
                     KQSQNNVTVDLTLQGQYITVQTNASGATLYVNQKPVTALTGEEITWGPIATDGSAAIYL
                     ERNGENGRETTKVETVTALSAYNLPFQKKSVEKTVVYNVTPPPTTHYVYNGFIFPDSDI
                     RKLTSTDLTYLSKEQLKIARNEIYARHGHMFQTKDMQAYFSKQSWYRENPYFTGKLTDI
                     ETYNVELIKSRE"
     gene            complement(6759..7181)
                     /locus_tag="EXW57_RS06355"
                     /old_locus_tag="EXW57_06515"
     CDS             complement(6759..7181)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332411.1"
                     /locus_tag="EXW57_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06515"
                     /product="hypothetical protein"
                     /protein_id="WP_002126015.1"
                     /transl_table=11
                     /translation="MCAGLLAQTPEEPQEPKAAMPLDQEFSINVTLYSARAWLSNDETF
                     AQTIWKGSRFASASHAGKSILPIGTVKIVNLSDDTITVTASSEKDDTLKIVVPPRSEGV
                     LTSSALSDVQASTSGGASKVTFLFHIFFSRDPGPAK"
     gene            7381..8715
                     /locus_tag="EXW57_RS06360"
                     /old_locus_tag="EXW57_06520"
     CDS             7381..8715
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="EXW57_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06520"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_002126016.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.4e-62, bitscore:
                     207.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGVIASTEKLIARDVKTFRDKYGIDAKVRHEVTKVDTEKKMVYAEHTETKDVFEFP
                     YDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEAVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGKER
                     VEQLETDKGTYKTDLVLVSVGVQSNTDFLEGTNIRKNHKGAIEVNAYMQTNVKDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMVDKRRAFKGTLGTGIIKFMNLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPSASPLHLKLLYHADTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            8875..9285
                     /locus_tag="EXW57_RS06365"
                     /old_locus_tag="EXW57_06525"
     CDS             8875..9285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="EXW57_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06525"
                     /product="DUF3908 family protein"
                     /protein_id="WP_002126019.1"
                     /transl_table=11
                     /translation="MAINMNTIEEWIAESNARNEEDLGNVVEEMKEVCVGLDNATLIYT
                     KNIFCFGKKVEVFFFFQDHVVIGEEKEEYIEIEKLKYDDITNSNLKTNDKNTTLELKFS
                     NGKAINLDSLNDNYGTKNWLFARQIKSIFKVI"
     gene            complement(9318..9908)
                     /locus_tag="EXW57_RS06370"
                     /old_locus_tag="EXW57_06530"
     CDS             complement(9318..9908)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 2.8e-15. Score:
                     47.2. Matches aSDomain: nrpspksdomains_EXW57_RS06370_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158829.1"
                     /locus_tag="EXW57_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06530"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_016101528.1"
                     /sec_met_domain="PCMT (E-value: 0.00013, bitscore: 20.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILQRLIEQAKNPRGTIGSSMLCIMNAAHTRLTNWALQKIHIRE
                     NAVILDIGCGGGKTIQTLSKRTPLGKIYGIDYSNQAVENSKKANMKDVKAAKVIIHQAS
                     VSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLLVAETFKIQYHMDKF
                     KTTEELVNLFYETGFTSVKCYEERGCLYLIGNK"
     aSDomain        complement(9462..9764)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW57_RS06370_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.80E-15"
                     /label="EXW57_RS06370_oMT.1"
                     /locus_tag="EXW57_RS06370"
                     /protein_end="149"
                     /protein_start="48"
                     /score="47.2"
                     /tool="antismash"
                     /translation="ILDIGCGGGKTIQTLSKRTPLGKIYGIDYSNQAVENSKKANMKDV
                     KAAKVIIHQASVSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLL"
     gene            complement(10001..11563)
                     /locus_tag="EXW57_RS06375"
                     /old_locus_tag="EXW57_06535"
     CDS             complement(10001..11563)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135039.1"
                     /locus_tag="EXW57_RS06375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06535"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_215566501.1"
                     /sec_met_domain="PF00881 (E-value: 8.1e-10, bitscore: 37.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPDTFLHHLHFSINEIMSSDKEIDWEDAPLPYKLYRNLPVIPLS
                     LEIPLTLRNSSTKPNLEEIGHYLWYSFGLTQLCQPTTNLENNKTTTLFRRFIPSGGALY
                     PNELYMYLKIDHYPDGIYHYDAAHHRLILLREGNFDSYLTEALGNRCNIHSCFGAAFVS
                     TMFWKNFFKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRAMNHLLGLSK
                     GEESVYAVIPLSTEPNTDWFHDDHHENKTITSHDLLQQIPPLTHEHFVRSKYVDEYPMI
                     KKINAASMIESTEHFQTFTREERQQYSAHAMQLPKVERLSYDFLQLCKKRYSPDSDFIL
                     TKWDAAELATLLQEASLSFPYYNDLDGKFLNENARVSLYGCFYNVKDIENGAYAYNSRT
                     HSIQPIRYGDLRYSLQSSMTMDNVNLFQVPLCLHVIGNKDYYKNKLGYRGYRIHQMEAG
                     MLVHKLVLAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQIPVGAYRARNWLKGS
                     LHN"
     gene            complement(11586..13535)
                     /locus_tag="EXW57_RS06380"
                     /old_locus_tag="EXW57_06540"
     CDS             complement(11586..13535)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="EXW57_RS06380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06540"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_215566503.1"
                     /sec_met_domain="YcaO (E-value: 3.1e-83, bitscore: 278.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 5e-138, bitscore:
                     458.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLTDYVHEQLCKQYSLIRQHTITEALPENIHLAL
                     VLHDGSPSSVHRDAELIFRSNNIPWLRAFTSFGEGIIGPYVKPLTTGCSHCADGRRFIA
                     GFDQKEMWELQRKYALKAENVTRRDVRATQNGMLQMCQLIHAETEKILAHGYSSLENEL
                     ILLDLQTLQCTRNSFLPDPLCPVCSNLPDDTADAAQVSLQPSLKTSTETYRCRSIHELN
                     TFLTRDYLDYRTGILNGKMQHSLLPFADVIINMPLLFGNEGVAGRTHSFSLSEATAILE
                     GLERYCGMSPRGKKTNVHGSFRELEDIALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLLQSRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMLERLRTITGYELYVFNATMEHGIPSIWVIAK
                     NTRQDGMNLVCAGGAHMEPIRAVKNAIHEIAGMLLITDEELEQKREKYENCLQDPYLVS
                     QMEDHSMLYGLKEAEERLHFLLRDDAPVQTFQEMNALQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVNQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYWAEP
                     LTNESLNPHPHPFP"
     gene            complement(13532..15451)
                     /locus_tag="EXW57_RS06385"
                     /old_locus_tag="EXW57_06545"
     CDS             complement(13532..15451)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="EXW57_RS06385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06545"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_002186383.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1159.9,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.4e-55, bitscore: 181.4, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.9e-11,
                     bitscore: 41.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFERYRAANVLIIGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     AETNYDRIHELSERAYANDDNVLIQEIDITIDRPLHEVFEPFDWILYVSQNGDIESLRA
                     IHTICREFKKNFIPAMCLSRIGLAGPVVTADREECWESAWHRLHETTLQSENPPEPFSP
                     IASAMLANVIVFELFKLVAEDSHRQHNPQFFLLNLETLEGKWHPFIKHLLATDEIFTID
                     TVQNLQENLAQRSGQYTSTELFRFFDTLTSKEAGIFHMWDEQDLHQLPLSQCNIQVANP
                     LSDGPTSPLPTITCGGLTHNEARREAGLTGVETYVAEMIHRLIPEHTDIGIGAGETMTE
                     GVYRALQKHLNNKLYERQSHMLEEITELYLTEIHDKHCRFYYDALSTIHEIPKVGMSEE
                     LLGFPVVWIGINDRWYGAANINITLALRNALQQALLHIQNEEIPYKANMLPESSIVLYS
                     TDPVRVAIQEEEEIPGVQSLQVALQNLTENNLYPFVFDLAIESFLRDNLDGVYGVLIAK
                     EDDQ"
     aSDomain        complement(15152..15451)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW57_RS06385_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.40E-57"
                     /identifier="RREFam011.1"
                     /label="EXW57_RS06385"
                     /locus_tag="EXW57_RS06385"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.4"
                     /tool="antismash"
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNS"
     aSDomain        complement(15185..15424)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW57_RS06385_Thiopeptide_F_RRE.1"
                     /evalue="1.50E-13"
                     /identifier="RREFam004.1"
                     /label="EXW57_RS06385"
                     /locus_tag="EXW57_RS06385"
                     /protein_end="89"
                     /protein_start="9"
                     /score="41.5"
                     /tool="antismash"
                     /translation="LKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDWIEKLMPMFN
                     GNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRD"
     gene            complement(15577..16833)
                     /gene="odhB"
                     /locus_tag="EXW57_RS06390"
                     /old_locus_tag="EXW57_06550"
     CDS             complement(15577..16833)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="EXW57_RS06390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06550"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_002168867.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESISEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAAVEVSTPAPANEQPKQETTEAPKA
                     AAPSAEQNKALQGLPNTNRPIASPAARKMARELGIDLNEVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKQSPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDM
                     SAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYDI
                     GIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGLKARDNKLSLKELQGGTFTITNGGV
                     FGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAVS
                     FLVAVKDMLEDPKSLLLEG"
     gene            complement(16963..19830)
                     /gene="odhA"
                     /locus_tag="EXW57_RS06395"
                     /old_locus_tag="EXW57_06555"
     CDS             complement(16963..19830)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="EXW57_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06555"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_002126030.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLIEKTMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVSEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYNHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTTKSFVILVHGDAAFPGQGVVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQSAGVLNADEVETITQFIQEELKAEYA
                     QVPPADTSAATIHVKVPEVVAKGIQPIDTGVSIESLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVIMTPKSLLRHPLTLSTGSELSEGRFQPALEQGNLGA
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHMVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVFSN"
     misc_feature    20478..20498
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 30.06"
                     /tool="antismash"
     misc_feature    20530..20544
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            20657..20866
                     /locus_tag="EXW57_RS06400"
                     /old_locus_tag="EXW57_06560"
     CDS             20657..20866
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="EXW57_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06560"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428506.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGE"
     gene            20869..21246
                     /locus_tag="EXW57_RS06405"
                     /old_locus_tag="EXW57_06565"
     CDS             20869..21246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="EXW57_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06565"
                     /product="permease"
                     /protein_id="WP_078202976.1"
                     /transl_table=11
                     /translation="MNYSQKYFVMMGIIFLFMSGFMILTGIMTHSAPPAPTYTLLAMMI
                     MCFCLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKIMTLSAVELLN
                     ILMALTMSTVFISFVVLSKRY"
     gene            21275..21457
                     /locus_tag="EXW57_RS06410"
                     /old_locus_tag="EXW57_06570"
     CDS             21275..21457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="EXW57_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06570"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_002086895.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLINQSL"
     gene            21592..21954
                     /locus_tag="EXW57_RS28630"
                     /old_locus_tag="EXW57_06575"
                     /pseudo=""
     CDS             21592..21954
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034130.1"
                     /locus_tag="EXW57_RS28630"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06575"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKKAIFFLLTCLLLIASITYIICNK"
     gene            21971..22240
                     /locus_tag="EXW57_RS06420"
                     /old_locus_tag="EXW57_06580"
     CDS             21971..22240
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126037.1"
                     /locus_tag="EXW57_RS06420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06580"
                     /product="hypothetical protein"
                     /protein_id="WP_002126037.1"
                     /transl_table=11
                     /translation="MQRVTSYPWSLRKIFVFFLCFILPPIGAIYILMNREALQKRDYIL
                     YLLFAAINISLWLSLMIFDRSMWMVAGHDVLGVIVIIFSNMNKS"
     gene            22321..22866
                     /locus_tag="EXW57_RS06425"
                     /old_locus_tag="EXW57_06585"
     CDS             22321..22866
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="EXW57_RS06425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW57_06585"
                     /product="hypothetical protein"
                     /protein_id="WP_002126038.1"
                     /transl_table=11
                     /translation="MRWKAGTFEKIETNDSSVEKIINTFKEQNLNGGAIISCFKVHNEN
                     FFKEIPHSKDGYEHFFRRIFNSLDIIHNLEELKIHTSEKYKFHFKEHLVVMLDGSIAAQ
                     ILWGGAYEGFKERPVIAKQLAVNVCQYMFQDRYEDIKVFESYRPWTDWFYDVAWDATWM
                     VLDSKEHKMWLVCATDTD"
     misc_feature    complement(22881..22897)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
ORIGIN
        1 acgttatatg gaagaggtgt aaaaaatggg agtagaaaaa attatagcag cgtttgaaaa
       61 tggcaagaaa gcatttattc cgtatgtaat gggcggagat ggtggacttg aaaagttaaa
      121 agaaagaatt cgttttcttg atgaagcagg agcaagcatc gttgaaatcg gtattccgtt
      181 ctcagatcca gtcgcagacg gtccaactat tcaaagggca ggaaaaagag cattagatag
      241 cggtgtaaca ttgaaaggta tttttcaagc attaatagag gtgaggcaag aagttcaaat
      301 tccatttgta cttatgacat atttaaatcc agtactcgca ttcggaaagg aacgtttcat
      361 tgacagctgt cttgaagcag gggtggacgg tattatcgtt ccggacttac cgtatgaaga
      421 acaagacatt attgcaccgc tccttcgcgt ggcgaatatc gctttaattc cactcgttac
      481 cgtaacgagc cctattgaac gaattgaaaa aattacgagt gaatcacaag gattcgtcta
      541 cgccgttaca gtagcgggcg taacgggagt acgtcaaaac tttaaagatg agattcgtag
      601 ttacttagaa aaagtaaaag cacacgtcca cttaccagta gtcgcaggat tcggtatttc
      661 aacacgagag caaattgaag aaatgattac aatatgtgac ggcgttgtcg ttggaagtaa
      721 agtcattgag ctgttagaaa atgaaaagcg agaagaaatt tgtgagttaa tacatgcagt
      781 aaaagaaaca gaagaggctt aagtctcttc tgtttctttt gtgtaataaa tgttaaaata
      841 tacagaaaat acttataact tagagggtga gaaggcatgc taagacgtaa actattatat
      901 ctttttttaa ctgtaccatt atacgcttgg ctcattagca tgacgaaaat agagttgatg
      961 gctctgtttt taggatatgt attcatcttt tcccaattaa atcgaataca agagcaatct
     1021 attttagaag tatgtatatt ttcgattagt atagaactat ttagtatcgt ttcgattgta
     1081 ttattaagtg aattattcca atggatccat tcatttgaat taataaaact tgggaatatt
     1141 gtattgcaag taatatgtgc ttatattgtg tttgttgtac tagaaaaaat gattggacag
     1201 cagacggttt ttcaggataa aagataaaat attagttatt caaaaaagga gccaagcggc
     1261 tcctttttaa aatctgttat aaaaataatt gaaaatcata acatctgtta tataatagtt
     1321 aaaaattgca atttttacga aaagagatga tagcatggcc atattgttgg cacttatccc
     1381 aattatgatg atttttattt gtttattttt gtttaaacaa acgtcattaa gggcttcatt
     1441 aatttcttat gccgtttctg tcggaatcgt tttactttcg ccaacgttcc aattagggat
     1501 aagtgaaact gtgcacgcaa cgattaaagg ttggttaatt tgttttattg tcggatacgt
     1561 tttatttttc ggtatttttt tatttcacct catgaacaaa atggggtaca tcgatcaagt
     1621 agcgcgtttt ctagaagaag ttacgcacga tcgcttacta caaatgcttc ttatgtgctt
     1681 tggcatttgt ccacttattg aatcagtaag tggattcgga attggtttta tggtcgcagc
     1741 acctattttt ctttcgctcg gttataaacc gtttcaagct gtgctactat cgtttatcgg
     1801 tttacttgca agttcatggg gcgcgatggc aacgggtacg attatcggtt ctcagcttat
     1861 taacatgccg ctcacaactc ttggtacaaa tacagcatta ttaagcatcc cgattttcgc
     1921 atattttatc ttcctttctt tatacgttgt cggtggctgg caggcagtta tagaaaagtg
     1981 taaggaagga gtaggattct ttctattatt ttctctcgga atctatcttt ctaacgcata
     2041 cgtaagtgtt gaacttgcag ggatattaag ttctatcgtt accattacat ttggctttct
     2101 aatcattaaa ttaaaaggca aaagtgagca aaactttata acagaacatg cggcgactgc
     2161 agagagagaa gtatctatta taaaaattat tagcccttat atattcttaa cagtttgtat
     2221 tttactttcc cgcctcgttc cagtattaca tgattttctt aggtcatatg cagttctcga
     2281 tttaaaatca tattcttaca aactagagct actatattca ccaggatttt ggctcgctat
     2341 gacttgttta tttacaatta ttttcttccg cattccatca aatattatta aacaatcact
     2401 ctcacaaacg ataaaacaat ggattccttt cgctattaca acgacaatgt ttatcgcaat
     2461 ttcagaacta atgggtgcat ctggtatgca ttcattactc gcaaaaacag ctggtgaaac
     2521 atttgggacg tttttcgttt tcgttgctcc tttcataggc ggaattggcg gctttttaac
     2581 aggtagtaac gcaggatcaa atgcgatgtt tataaagcta caaatgcaaa cagcgcaaaa
     2641 cgtagcgatc ccgtggcaat atgtcacaac actccaaaac accgcatcat cagtagccac
     2701 aatcgcttgt ccatcacgga ttacactagg cgcgtattta tgtaatatcc cttatcgtga
     2761 aaatgaacta ttaaagaaga cgacgttaat gatttttggt gcggtgttgc ttgtagtggt
     2821 ggaggttatt gtttggtata tgttgagaaa ataagaaatc ctcctgggaa aggaggattt
     2881 tctttttata tggataatgc ctaaagtatg aaaagcttct actaaatgaa taggagatga
     2941 aagagatgcc cttaaaaaac tacggtgtat taaaaggtac agttgtacaa tctaagattg
     3001 gaaaagggaa aacacctcat tatcaagttc atttacaagg cgaagcagga gttaattatc
     3061 gcattgcaat taacgtgaaa tcgcaaagct atccgtcgga agttttatat tttgcgagta
     3121 acaatattcg atcagaggcg attcatattt taccgacatt accgttcggt tttacggaag
     3181 tgaaaaacaa tgagccgaaa gtagctttag attatgtaag aggtaattta tttgattcaa
     3241 agcaaatgat tcctttacct gctgaaaaat cgggatctga taatgattta aatgagaaaa
     3301 tagaacatta tataaaaaga gcaatagatg agaaagcaat tatttatgcg tttggtgaaa
     3361 ggtggggacc agaagaaaag gttccggatt cgtatttcca ctttacacct ggaaacggta
     3421 tacacgatat tcatatgaat caagggaatg tagagaaatg gcaaggtgat gatggcaaat
     3481 ggcaagacgg tgggatattg attcactttg agaagaagga agagtggatt ggtatttttc
     3541 ttgcctttca gtcacagtca tggtgtaccg atgaagaagg gcacgctcgt gttccggttg
     3601 agcattgtga ttataagaga aataattgat gagaagaggg cgttcacaat gaacgccctc
     3661 ttcttatttt ataaaacaca aaactcacaa gtgtagaaat acaagagaaa agaagcgcca
     3721 cactagaaaa cgcgatgaaa tacatattat acttcatcat tttaccgatt agttggttac
     3781 tatcgtactg aaacagtccc gctattatat tgaataaaaa taatacgata aacatgacga
     3841 taacaccgtc tattgatcct ttaatgtctg gtttacttaa agcgatatgt gcggaaatgc
     3901 aaatagcgat aaataaaaat aaccaaaatg aaggattcaa taaattgcta aatgtaaata
     3961 agcttttcaa taatacaaac gtcgatagta gcatgttttg gatcatgtct aagctaatag
     4021 aagtcgatgt aacagttttt tccagattcg tattaaataa agaatatgaa tctggtacga
     4081 aatagcgcat taaaagtatt aaggcagtaa tcccagaaat aataggaccg atgccgataa
     4141 agaaattacc gattcgttgg tatatacttt tttgattgta ttgatgttgt acgtaaccta
     4201 aagctccctg acttgtatct gttgggaaaa actgcgttgc tacaatttta tgacgaaata
     4261 atagacacat aattgcatgt ccaagctcat gaacgggaac accaatccac gcggttaaaa
     4321 gaaaaccttt cctaccaaaa gctctcgacc aatacgttcg tgtgagagat tctaaataac
     4381 ctaatataaa tccaattaca atgatgacac caattaaaga aaataattgg atcacacttg
     4441 taaggagtgt ttgaaaaatc gagtttacaa attccactgt cttcatccaa tctgtttaaa
     4501 gtttcacttt atttgctctg tttcataata acattatttt tctatattac tagcacacat
     4561 agtttcgttt aaaagaagga tttcatattc tttttcttgt agtcatgttt tatgtacaaa
     4621 gtcatatatt gaatttgtaa caccctataa ggtatatgct taaggaggga tgagagaatg
     4681 aaatgtccgg catgtaatac tgaaaatgca gcggaagcaa ggttttgcgg aaattgtgga
     4741 cattcgttaa cggaagaagt ggtagcgagt ggtgggcagg aagaagggca gctatcgcgc
     4801 ccggcacgag taaaggaaac tcgtccgaat gaaacggtag agcaagtgaa acaatttgca
     4861 agtggctatt ttcagttctt taaaaatgct tttaaatcac catcggccat tatggaaagt
     4921 ggaaatattg aagtgcgaaa tggaattgta agtcttgtgc ttatttgctt tttaggagca
     4981 tgtatttttt atagaatgat gagcgcagcg gcgactgtta cgaggacatt agtgccagat
     5041 atagctactc ctactttctt tggagaatct gtaatggtct ttttcttttt attaatttta
     5101 actttatttg tcggatttat tatttttgta agtggtaaga tgatgaaatc atctttttct
     5161 tttcttgaat cattcggtat atgggggacg atagcgacgc cagctattgc tatactagtt
     5221 ctttcttttc tatttagttt cctattgatc ttttttttac caatcttatt agggctggct
     5281 acaacgtata tgggaattag tataattgta gctatattaa aactagacaa cggcggagta
     5341 gatcctgttt acacacttat tatcgcaaat gttttaatcg gaattgcaac gtttatcgtg
     5401 ttttggtctt acattaaaac gataatccaa acctttatcg ggggattaac aggcttctaa
     5461 cgaaaaggtg gttgaatgga tgaatgtatg tacaaaatgc ggagctcagt atgaagatgg
     5521 agtgcaattt tgccaaaact gcgggatgaa gagggaaagt cttgtagtaa agaagaaaat
     5581 gagcggtggt acaaaagttg gcattacact cttaacatta cttgttatag taattgttgg
     5641 attgtatttg tatggatcat cgtattataa gcagacggca caagtagacc gaatgattac
     5701 tattttacaa gagagggacg gggagaaatt agctgagatc atcacggcag atgatccaac
     5761 cgttattgta acgagagaga gtttaacgcc tctattttca tatataaaag aaaatccatt
     5821 ttacgtgaat gaattgaaag aatatttgag gcaaggtgaa aaacaagggg atggaataga
     5881 aagagcagat ttttctttaa cgaaagatgg gaaacaattc tttttatttg atcggtataa
     5941 attgaaagcg aagacgtatt atacgactct gcttacaaat gaaaaaggta catctttaaa
     6001 attgaacgga aaagaaattg ataagacaaa tgacaaaaag tttgagaagc aatatggacc
     6061 gtttcttcct ggaactcaag tatttcaatc tgaatataaa aatgactatg taaaactatc
     6121 acgtgaggaa aaggttgtac ttatgaaaca aagtcaaaat aatgtaacgg tagatttaac
     6181 gttgcaaggg caatatatta cagttcaaac gaatgcgtct ggtgcaacat tgtacgtgaa
     6241 tcaaaagcca gttactgcgt tgactggaga agaaattacg tggggaccga tagcgactga
     6301 tggaagtgcg gcgatttatt tagaacgaaa tggagaaaac ggaagggaaa cgacaaaggt
     6361 agaaacggta acggcacttt cggcttataa tcttccattt caaaagaaaa gtgtagaaaa
     6421 aacagttgtt tacaatgtta ctccaccgcc tacgactcat tatgtatata atggtttcat
     6481 cttccctgat agtgatattc gaaaattaac gagtacggac ttaacatatt tatcgaaaga
     6541 acaattgaaa atagcaagaa acgaaatata cgcaagacat ggacatatgt ttcaaacgaa
     6601 agatatgcaa gcgtattttt caaaacagtc ttggtataga gaaaatccgt attttacagg
     6661 aaagctaaca gatattgaaa cttataatgt tgaattgatc aaatcaagag aataaacgcg
     6721 tgaaaaaggt acagtgcata gctgtacctt ttctatggtt atttagctgg accaggatcc
     6781 cttgagaaaa agatatgaaa gaggaatgtg actttgcttg ctcctcctga tgtacttgct
     6841 tgcacatcag ataacgcact agatgttaaa acaccttcag aacgaggggg tacgactatt
     6901 ttgagagtat catctttttc tgatgaggca gtaactgtta ttgtatcatc agataagttt
     6961 acaattttaa cagtaccgat tggtaagatg gacttgccag cgtgtgatgc tgaagcaaag
     7021 cgagagcctt tccaaatcgt ttgtgcgaaa gtctcatcat tagataacca agcacgagcg
     7081 ctgtataatg ttacgttaat agaaaattct tgatcaagtg gcatggcggc tttcggttct
     7141 tgcggttcct ctggagtttg agcgagaagg ccggcgcaca tgtatgtttc acctactttc
     7201 aatagttact gttatagcat attaaacatc ttgtttataa gacacgacgg atacctattc
     7261 atgcataggt ttgtgcacca aatttgtaga tggaattcta tttctttaca atggaagtag
     7321 gtgttatttc tataaaatat ggaaatcgta aagagtatgt aaaaaagaag gagtggtaaa
     7381 gtgaactatg tcattattgg cggagatgca gcaggtatga gtgcagcaat gcaaattgtt
     7441 agaaacgatg aaactgcaaa tgttgtaacg ttagaaaaag gtgaaatcta ttcatacgct
     7501 cagtgcggat taccgtatgt gattagtggt gttattgctt ctactgaaaa gttaattgca
     7561 cgcgatgtaa agacgtttcg tgataaatat ggaattgatg cgaaagtacg tcatgaagta
     7621 acgaaagtag atacggaaaa gaaaatggtg tacgcagagc atacggagac gaaagatgtt
     7681 tttgaatttc cgtatgaccg tttattaatt gcgactggag tgcgtcctgt tatgccagaa
     7741 tgggaagggc gagatttgca aggcgttcat cttttaaaaa caattccgga tgctgagcgc
     7801 atattaaaaa cgctagaaac gaataaagtt gaggctgtaa ctattattgg cggcggtgca
     7861 attggactag agatggcaga aacattcgtc gaacttggta agaaagtaag aatgattgag
     7921 cgaaacgatc atattggcac aatttatgat gccgatatgg cggaatatat acataaagaa
     7981 gcagataaac ataatattga aattttaacg aatgaaaatg taaaagcgtt taaaggaaaa
     8041 gaaagagtag aacaactgga gacggataaa gggacgtata aaactgatct cgttttagta
     8101 tctgtcggtg tacagtcaaa tactgatttt cttgagggga caaatatacg taaaaatcat
     8161 aaaggtgcaa ttgaagtaaa tgcttatatg caaacgaatg tgaaagacgt atatgctgct
     8221 ggtgattgtg caacacatta ccatgttata aaggaaattc atgaccatat cccgctcgga
     8281 acgactgcga ataaacaagg gcgacttgcc ggactcaaca tggttgataa acgcagagca
     8341 ttcaaaggta cgttaggtac aggcattatt aaatttatga atctgacgct cgcaagaaca
     8401 ggcttaaatg aaaaagaagc gaaagggcta aacatcccgt ataagacggt caaagtagat
     8461 tcaacaaata tggcgggcta ttacccgagt gcttcgccac ttcacttgaa attactatat
     8521 cacgccgata cgaaacaatt attaggcggt caagtaattg gagaagaggg cgtagataaa
     8581 cgtattgatg ttatcgcgat ggcacttttc aataaaatga gtattcacga tttagaagat
     8641 gtcgacttaa gttacgcacc accatataac agcgtttggg atccaattca acaagcagca
     8701 aggagagcgg aatagcactt ttttaagtgc tatttttttt gtgaaagggg aataaataaa
     8761 gtttcacttt attttgaata taccgttcac ccttgaaaac atagtacgta tcgcttatat
     8821 tgtcatatag tatttgtttt ttaataaagc aatgaacgaa ccagggggca cagtatggca
     8881 attaacatga atacaatcga agaatggatt gctgaatcaa atgcaagaaa cgaagaagac
     8941 ttaggaaacg ttgttgaaga gatgaaagaa gtatgtgtcg gacttgataa cgcgacatta
     9001 atttatacga aaaacatatt ttgtttcggt aagaaagtag aagtattctt cttcttccaa
     9061 gatcacgtcg ttatcggaga agagaaggaa gagtatattg agattgaaaa attaaagtat
     9121 gatgacatta caaatagcaa cttaaaaaca aatgacaaaa atacaacgtt agaactaaag
     9181 ttttctaacg ggaaagctat taatttagat agtctaaatg ataactacgg tacgaaaaac
     9241 tggttatttg caagacaaat taagagtatt tttaaagtaa tctagtaaaa aaggcagacc
     9301 ttgaaaggtc tgctttttta cttatttcct attaaataaa ggcaccctct ttcttcataa
     9361 catttcacgc ttgtaaatcc cgtctcataa aaaaggttta ctaattcttc ggtcgtctta
     9421 aatttatcca tatgatattg gattttgaaa gtttcagcga ctagtaaaaa ggatccattc
     9481 ggttttaaga cgcgaaatac ttctttcata tcattctcaa catcaggcca aaagtagtgg
     9541 gtttgaaaag cggtaatgag atcaaagaag tccggatgat atggaataga ggagacgctt
     9601 gcttgatgaa taattacttt cgctgctttg acatccttca tatttgcttt ctttgagttt
     9661 tcaacagctt gattggagta gtcgatcccg tatattttcc caagcggagt tcgttttgaa
     9721 agagtctgta tggttttacc acccccacaa ccaatatcta aaataactgc attttcacgt
     9781 atatgtattt tttgtaaagc ccaatttgtt agtctcgtat gcgcagcatt cataatgcaa
     9841 agcatagagg aaccaattgt cccgcgagga tttttcgctt gctcgattaa tctttgtaaa
     9901 atactcaatt caaactctcc ttttatataa gaatatgtat ttatttcgct tttaataatt
     9961 taactccttt aaaaaaagca cgccattaat cggcgtgctt ctaattatgc aaggaccctt
    10021 ttagccaatt tcgcgctcga tacgccccaa ccggaatttg aatgagtgaa gtttcatttc
    10081 cggcatcaat cccgtacaat tgatcgcatg aatttgtatc aaaacttagt aacggatgcc
    10141 cgcccatccc catagcggtc gcagctaaaa cgagtttatg aacgagcatg ccagcttcca
    10201 tttgatgaat tcgatatcct ctataaccta atttattttt atagtaatct ttatttccga
    10261 ttacatgtag acaaagtggt acttgaaaaa ggtttacgtt atccatcgtc atactggatt
    10321 gcagagaata acgaaggtct ccgtaccgaa ttggctgtat ggaatgtgtc ctactgttat
    10381 aagcgtaagc gccgttttct atgtctttta cgttataaaa acatccatat agtgagactc
    10441 gtgcgttttc atttaaaaat ttgccatcaa ggtcgttgta ataagggaag gagaggctcg
    10501 cttcttgtag tagagtagcg agctcggctg catcccattt cgttaaaatg aagtcagaat
    10561 caggtgaata tcgtttttta caaagttgta aaaaatcata tgataaacgt tccactttag
    10621 gtagctgcat agcgtgtgca ctatattgtt gtcgttcttc acgggtaaat gtttggaagt
    10681 gttctgttga ttcaatcata gaagctgcgt ttattttttt tatcatcgga tattcatcta
    10741 catattttga gcgaacgaaa tgctcatgtg ttaacggcgg gatttgctgc aacaagtcat
    10801 gagaagtaat agttttattt tcgtgatgat catcatgaaa ccaatctgta ttcggttctg
    10861 tacttaaagg aataacagca tacacacttt cttcaccttt tgacagtcca agtaaatgat
    10921 tcattgcccg atctagaaac tgaaaatata caccatttgt ataaccaaat tgttttgcgc
    10981 attcaagtaa ttgaccgatt agaacaccac tatctaatcc ttgcagacga tacgaaaagt
    11041 tattgtattt aaagaagttt ttccaaaaca tagtggatac aaatgcagca ccaaaacaag
    11101 aatgtatgtt acaacgattg ccgagtgctt ctgtaagata agaatcaaaa tttccttcac
    11161 gaagtaagat aagacggtgg tgcgcggcgt cgtaatggta aatgccgtct ggataatgat
    11221 caatttttaa atacatatat aattcattcg gatataaagc acccccagaa gggatgaatc
    11281 ttcgaaatag agtcgttgtt ttattatttt ctaggttagt agtaggctga cataattgtg
    11341 ttaaaccaaa tgagtaccaa agataatgac cgatttcctc taagttaggt ttagtagaag
    11401 aattccgcaa agttaatggg atttctaaag agagagggat tactggtaaa tttcgatata
    11461 atttataagg aagtggtgcg tcttcccagt caatctcttt atcggacgac ataatttcat
    11521 taatagaaaa atggagatga tgtaaaaaag tatcaggttg catcaaattt ccccctcact
    11581 atgaattatg gaaacggatg cggatgtgga tttaaacttt cattcgttaa aggctcagcc
    11641 caatatccaa gtgtcatcgg tacggtatac actctatcca gtcctgtaac ccgagtgaga
    11701 tggtgaccga acgtcatcgg taacatgcct ggaataatta cttttacaca atgtaagccg
    11761 ttcttttcta taagggggac cgtttgattt acaacaatta cttcaagtcc agattgatgt
    11821 aacctgttta aaagttgatg aagatcagat gttaaatcca tatcaaatga ttgtaatgca
    11881 ttcatttctt ggaacgtttg cactggagca tcatcacgta aaaggaagtg aagacgttct
    11941 tccgcttctt tcaatccgta cagcatacta tgatcttcca tttgcgaaac aagatatgga
    12001 tcttgtaaac agttttcata tttctctctt ttttgttcaa gctcttcatc tgttataagt
    12061 aacatgcccg ctatttcatg aattgcattt tttacagctc gaattggttc catatgtgcg
    12121 ccgccagcac agacgagatt cataccatct tgccttgtat ttttcgcaat gacccatatg
    12181 ctcggaatac catgttccat cgtcgcgttg aaaacgtata attcatatcc agtaattgtg
    12241 cgtaagcgtt ccaacattag ttgcaattca gtatcattgg ctgaactaag atcgagacgg
    12301 ggaagaggta attcggcata ccaagtgagc aaaaaggcgt cacgctctac aatttctaaa
    12361 atgccgtgaa aaattgcttc ttctaaacta ccaccaattg cacatccatt tgatgtttca
    12421 tacacgaaag catctctatg accaaggcta taataagcga ttgattctgg aactagaagg
    12481 ggcctgcttt gtaataaaga atatccccat acccagtttt gctcataatc aggatcaaac
    12541 ggcttaaatg gaaaactatc acgattgtaa tgttcatttg tatgcacacc aagtgtgagg
    12601 ggattcagtg caatatcttc tagctcacga aaactgccat gtacatttgt tttttttcca
    12661 cgaggcgaca taccgcaata gcgttctaat ccttctaaaa tagcggttgc ttcactaagt
    12721 gaaaatgaat gagtccggcc cgcgacacct tcatttccaa acagtaacgg catgtttata
    12781 atgacatcag caaacggtaa tagagaatgt tgcattttac cgtttaaaat accagtccgg
    12841 taatctaaat agtctctcgt taaaaatgtg tttagctcat gaatggaacg acagcgatac
    12901 gtttcagtac tcgttttcaa acttggttgt aaagaaactt gcgctgcatc tgctgtatcg
    12961 tcaggcaaat tgctgcatac cggacagaga gggtctggaa gaaacgaatt ccgggtacat
    13021 tgtaacgttt gtaagtccag taaaatgagt tcgttttcta aagaagaata tccatgagct
    13081 aatattttct ctgtttcagc atgaatgagc tggcacattt gtaacattcc attttgggtg
    13141 gcgcgtacat cacgcctcgt cacgttctct gcttttaatg catattttcg ttgtagttcc
    13201 cacatttctt tttgatcaaa gccagctata aaccggcgtc catcagcgca gtgggaacat
    13261 ccagttgtaa gaggcttcac gtaaggaccg ataatacctt caccaaacga agtaaacgcg
    13321 cgaagccacg gaatattatt tgagcgaaag ataagctcag catcacgatg tacggaagaa
    13381 ggagacccgt catgtaaaac gagagcaaga tgaatgtttt cagggagagc ttctgtaatt
    13441 gtatgctggc ggatgagtga atattgctta cacaattgct catgtacata gtctgtgagt
    13501 aggccatctc ctataagtag tatgttttga gtcattggtc atcctccttt gcaattaata
    13561 ctccatatac accgtctaag ttgtctctta aaaatgactc aatagctaaa tcaaaaacga
    13621 atggatacaa gttgttttcc gttaaatttt gcaaagcaac ttgtaaagac tgtacgcctg
    13681 gaatttcttc ctcttcttgt attgctactc taacaggatc cgtactatat aaaacaatgg
    13741 atgattccgg taacatatta gctttataag gaatctcttc attttgaata tgaaggagtg
    13801 cttgttgcag agcatttctt aatgcgagtg ttatattaat atttgccgca ccataccatc
    13861 tatcattaat accgatccaa acgacaggaa aaccaagtaa ctcctcactc attcctactt
    13921 taggtatttc atgaattgta gagagagcat cgtagtaaaa cctacaatgt ttatcatgaa
    13981 tttcggttaa ataaagctct gtaatctctt ctagcatatg tgattggcgt tcatataact
    14041 tattatttaa atgtttttgg agtgctcggt atacaccttc tgtcatcgtt tccccagcac
    14101 caataccgat atcagtatgt tcggggataa gacgatgaat catttcagct acatatgttt
    14161 caactcctgt taagccagct tcgcggcgtg cttcattatg agttaatcca ccgcaagtta
    14221 tagtaggaag gggagaggta ggtccgtctg ataatggatt tgcaacttga atattgcact
    14281 gtgataaagg caattggtgt aaatcttgtt catcccacat gtggaatatg ccagcttctt
    14341 tagaagttaa cgtatcaaaa aaacgaaaaa gttcagttga agtatattgt ccggaacgtt
    14401 gggcaaggtt ttcttgaaga ttttgcaccg tatcaattgt aaagatttca tcggttgcga
    14461 gaagatgttt tatgaaaggg tgccactttc cttcaagtgt ttccaagttt aataaaaaga
    14521 attgaggatt atgctgccta tgtgaatctt cagcgacaag tttaaataac tcaaaaacga
    14581 taacatttgc taacattgca gatgcaattg gtgagaaagg ttcaggtgga ttttcacttt
    14641 gtaaagtagt ttcgtgtaga cgatgccaag ctgattccca gcattcttca cggtctgcgg
    14701 ttacgacggg tccagctaaa ccaattcttg ataagcacat agctggtatg aaatttttct
    14761 taaattctct acaaatagta tggattgctc ttaaactttc aatatctcca ttttgggaaa
    14821 cgtataaaat ccagtcgaaa ggctcgaata cttcatgtaa agggcgatca attgtaatat
    14881 ctatttcttg aataagtaca ttgtcatcat ttgcatatgc acgttcgctt agttcatgaa
    14941 ttcgatcgta gtttgtttca gcacgatctg taacaagata atggaatgta ggtaaaccag
    15001 attctaataa agaagaaact agggaagtaa gcatatcacc agaaccaatt ataagcacat
    15061 ttgctgcgcg gtacctttcg aattttaaag cgcctgaatg ggaatcagct tctagaaact
    15121 caatttgcga agcgtatctg tcgagtaatg cactgtttaa ttcgtgggga gcatcttggc
    15181 ttacatcacg aatgaaacca ttttcatata aaatctctcc aatttcaaat acacgatttt
    15241 gataggggag agggagacca tcggttattt ctgtcaaaga atgattaccg ttaaacatag
    15301 gcattaattt ctcaatccag tcataaattc catcaccatc catacggaat gaactggagt
    15361 tatttcgaaa gtaaacaccc ccgtttgaat cggggaggaa gaaagtatcc ttatttgctt
    15421 taagttttgc atgaactgga aggttattca tgtttatccc ccttacgttt taggcataca
    15481 ttgttagtct atgtagtgtg atttgtcccg tatgaacata atgaaaaaag gctgtagaat
    15541 gattcattct acagccttta atagattaat aatctatcaa ccttctaata ataatgattt
    15601 tggatcttca agcatatctt taacagcaac aaggaagcta actgcttctt taccatcaac
    15661 aatacggtga tcgtaagata gtgcaaggta catcattgga cggttttcca tacgctctgc
    15721 atcaattgca actggacgta cttggatttt atgcatccct agaataccta cttgtggact
    15781 atttaggatt ggtgtcgaca ttagagaacc gaacacgcca ccgtttgtaa ttgtaaatgt
    15841 accaccttgt agctctttta atgaaagttt attatcgcgt gctttcagac ctaaattacg
    15901 aatctcgctt tcaatttcag cgaagttcaa ttggttagca tcgcgtacaa ctggaacaac
    15961 taatccatct ggagctgcta ctgcaatacc gatatcatag aattttttaa tgataagctc
    16021 atcgccttga atttcagcat ttaataatgg gaactgtttt aatgctgcaa caactgcttt
    16081 tgtgaagaat gacataaagc caagacgtac atcatgtttt ttctcgaaag catctttgcg
    16141 ttctttacgt aattccatga ttgcactcat atcaacttcg ttaaatgtag ttaacattgc
    16201 agatgtttgt tgaacttcta caagacgttt tgcaattgtt tgacggcggc gggacatttt
    16261 cacacgctca actggttttt caaattcagt ttttgcaact ggagccgggc tttgttttgg
    16321 agcagctggt gcttcttttg gcgctgcagc gtgagcttgt acatcatgtg gtctcacacg
    16381 tccaagtgga tctgtgctac gtacttcgtt taaatcgatt cctaattcac gagccatttt
    16441 gcgagcagct ggtgatgcga taggacgatt tgtatttggt aaaccttgca acgctttatt
    16501 ttgttcagca cttggagctg ctgctttcgg tgcttcagta gtttcttgtt ttggttgctc
    16561 attagccgga gcaggtgtgc ttacttcaac cgctgcgccg tttgcatcta aaattgcgat
    16621 agtagcacca acttcaactg tatctccagg ttcgcctagt aacttcgata caatacctga
    16681 atcctctgca atgatttcta cattgacttt gtcagtctca agctcaacaa cgctgccacc
    16741 tttctcaact ttgtcgccta cgttgataag ccattgtgaa atagttcctt ctgaaataga
    16801 ttctgcaagc tcaggtactt taatttcgat cattttaaat gtcctcccct tatttgccta
    16861 acggtgtgtt ttatcttctt taatcttcgg taatctccat ttgttagcct ggctgtggca
    16921 gactatctgc cacagccaag cctgaaaaac tcattgttac tttcagttgc tgaaaacttc
    16981 aatttcttgt ttatcttgac ggaagttgta cttcacatct aaagcgtgtg caacgattaa
    17041 ttcttgctca gctttgtgag cgaatggatc gccaccagat gggctagaac gatccgggcg
    17101 tccaatgtaa cctgttttca ctttatcccc agctagttcg aacagaattg gagccatgta
    17161 atgccatgcg cccatattac gaggttcttc ttgaacccaa atgatttctt ctaagttttt
    17221 aaagcgttta ataatagatt gaactttttc agcagggaat gggtacaact gctcgatacg
    17281 aaccatatga acttcatcta ggctgtactc atgcttacca ctttcgattt ctgctgctaa
    17341 gtcaattgcc attttacctg tacttaaaac aagacgtttt actttatttg gtttcgcacc
    17401 aaggtttcct tgttctaaag caggttggaa acgtccttca cttaactcac tacctgtaga
    17461 aagtgtaagt gggtgacgta ataagctttt cggcgtcata attactaatg gtcgaacagc
    17521 ttctgttcct aagatagatg cttgacggcg caagatatgg aagtattgtg ccgcgctcgt
    17581 taagtttgca actgtccagt tgttctccgc agctaattgt aagaaacgtt ctggacgtgc
    17641 actagagtgt tctggccctt gaccttcata accgtgtggt aatagaagaa ctaaaccaga
    17701 tttttgaccc cattttgctc ttcctgctga aacatattga tcaaataatg cttgcgcagt
    17761 atttgagaag tcaccgtatt gagcttccca catcacaaga gtttctggag caaatacgtt
    17821 gtaaccatat tcgtaaccaa caacagcagc ttctgataac ggactgttat gaacagagaa
    17881 tgatgcgtta atgttcggta aacggtgtaa tggtgaatat gtttcgtttg tatcagtatc
    17941 gtgtaatacg atatgacggt gcgcgaatgt accacgctgt gaatcttgac cagttaaacg
    18001 aattggcgta ccttcttgca aaatagaagc gaatgctaac gattcagcaa gtgcccattc
    18061 aattttaccg ttctcttcaa gagcatcttt acggcgctca agaattttct tcacttttgg
    18121 atatacgtta aagccttcag gccaagataa tagtccttca ttaattgcac gaagtgattc
    18181 aattgaaaca ccagtgtcaa tcggttgaat tccttttgca acaacctctg gaactttaac
    18241 gtgaattgtt gcagcactcg tatcagctgg tggcacttgt gcgtattcag cctttaattc
    18301 ctcttgtata aactgagtaa ttgtttcaac ctcatctgca ttcagaacgc cagcagattg
    18361 taattgatct gcataaattg ctcttacagt tgggtgattt ttaatttttt tgtacacttg
    18421 tggttgcgta actgctggat catccatttc gttatgacca tatcggcggt aaccgattaa
    18481 atcgattaag aagtcctttt tgaacagcgt acgatattgg atcgcaaggt ttgcagcagc
    18541 aagacaagct tccggatcat cagcattcac gtgaacaatc ggaatatcga aaccttttgc
    18601 aaggtcgctt gaatatttag tagaacgaga atcatagcta tcagtcgtaa agccgactgc
    18661 attatttgcg ataacatgaa tagttccgcc agtttggtat gcattcaatc tacttaagtt
    18721 gagtgtctca gacacaacac cttgaccagg gaatgcagca tcaccatgaa ctaaaattac
    18781 gaatgatttt gtagtatctt gttctggaag accagatttt ttacgattct cttgagctgc
    18841 acgtgcgaaa ccttcaacaa cagggttaac gaactcaaga tgactcggat tatttgctaa
    18901 tgtaacacga gtgctaacct cttcattacc aacgacttgt tctctaccta aatggtattt
    18961 cacgtcgcca gtccagccag catttgccac tgcaccttct atttttgcat gtttgaattc
    19021 tgcaaacatg tgattatatg gcttttctaa tacgtgagcg agtacgctta gacgaccacg
    19081 gtgagccata ccaatcatga catcttcaac gccgccttta gcaccttctg aaacaatttc
    19141 atctagtaca ggtacaagca tatcaacgcc ctctattgag aaacgctttt gaccaacgaa
    19201 tgttttatgc aagaattgct cgaaaccttc aacagcagtt aaacgtttta aaagagcagt
    19261 tcgtttttta tttgataatg gttgacgcaa tgaatttgat tccaccattt gatgcaacca
    19321 cgcgcgttct tcactatctt gtatatgtga gaattcataa gctaaagatt ttgtataaac
    19381 gtcttttaat ctatgaatta catcaagtgc agtgtgaata ccctctggtg catcttgcca
    19441 tactgttttt gctggaatcg ctttcaagtc agcatcgctc agttcgttca ttgttttctc
    19501 gataagagat tgtccgtttg cagcatcttc catcggatta atgtgagcca atgtatgccc
    19561 gaaagaacgg atctgttcaa caagttgaac gactttaaga atcttttcaa tgttccctgt
    19621 gttttgagga gaaaaatgtg ttgctgtgtt gtcccctgtt acgacatcat cttgaaacga
    19681 aggagctcca aaaatttcaa aaagctcttg taattccgga tcaacagaac ctgctccagt
    19741 tacgtaaaga tcatactgtt caataacata accaaggttc ggaccatgga acttggccca
    19801 agggtttgtc gttgtattct tcctcgtcat ttgtttaaac ctcccaatgc atataatcct
    19861 ttttccatac aaaaaggtgc attttgctct tttcaataat tgatgaacca ataatcaatg
    19921 taaatgtttt tctttactct tatgttatta caataattta cataatacca aacactatta
    19981 cttatctgtt ttgtaaaaaa acattcacaa taacttatca cccaagttaa tctttcatgt
    20041 tataaagtaa tttcacggga aaacggggtg gatatatttg gtatacctac attaatacct
    20101 ataattgttg catttaaata taagtataac tatcagaatg tttcgataaa gtttagttcg
    20161 aattatgtat attggaataa taagcgcttt cattgatatt atacaacaat ataacggaat
    20221 atagtataaa aaataaaaaa ttatgaattt accataaact ttatctcgat agtgttaaat
    20281 atcgaaagga aaatgaagga tttctacaaa aaaagtggct atacataaaa aatgcttcat
    20341 aaaccgttag tttctataaa tatggcgaaa aataacgtaa aaacaatagc gtatttcacc
    20401 cgataaagag cagaatgaaa cattttaaaa ggataaaaca aatatggaga tattaaattt
    20461 tcataaaaac ggagaggaga tatagtaacg gctatataca ttgttccatg tttcatttca
    20521 aaatagacgt gctgaatttg aaaaagtttc ttctatataa atagaatgaa aaatagacga
    20581 aatgaatgta aaggaaactt gacgtaaagt ttcctttaca tatatactcg gtataaggaa
    20641 ggagggagaa atttccttgg aaaataaaat ggttgaatac cgaaaaaaat ttggactatc
    20701 tcaagaaaaa ttggctgaga aacttggagt ttccagacaa accatcattt caattgaaaa
    20761 gggaaaatat gatccatcac ttccgttagc atttgaaata gcaaaaacat ttcagacaac
    20821 gatagaacat gtatttattt atgaaggaaa ggaagagggg gaataaagat gaactattca
    20881 caaaagtact tcgttatgat gggaattatt tttctattta tgagtggatt tatgatatta
    20941 acaggtataa tgacgcattc tgcaccaccg gctccaacgt atacattgct tgcgatgatg
    21001 attatgtgtt tttgcctaag ctacttgcac ccgcaattta aagaaaaaga tgagcgaatg
    21061 aaactcattc gttataaagg aatgttcttc agtttttttg cactaacggc atactatctt
    21121 cttttctcta ttggcttaaa cttaaaaata atgacgctat ctgcggttga actattgaat
    21181 atattaatgg cacttacgat gagtacagtt tttatatcgt ttgttgtttt atcgaaaaga
    21241 tattaagatg taaaagagaa aggaagatta acatatgcaa atgatgtatg cttttggcat
    21301 ggggcttgta ttatttttag ccgtattctt atttattcgt aaagacgttc aaggcggaac
    21361 gttaacgaaa cgaggatttt ataaaatgat cggctgctta gttgttatgt ttatagcgat
    21421 tatcgtaatg atcgttttaa taaatcagtc attatagaac ttaaaaacgg aaccttactt
    21481 ttgtaaggtt tttctttttg gaaataaatc taaaaattac cataaaatcc atttgctatc
    21541 tatatcttgt attatataat ccaataaaat gatagataag gagaatagta tatgaataaa
    21601 aaagctatct tctttttatt aacatgtcta ctacttatag ctagtattac ttatataata
    21661 tgtaacaaat gagaacaagt tccacctata ttagtatagg aggggcatga atactacgtt
    21721 acgaatgaac ctgccaaagc agaagaagcc gggcaaaaac ttggagaagt gacgaagaaa
    21781 attgaaacaa gcaaacagcc tactaaagat agtgaatcca acgtattaga agaaaaaaca
    21841 gaagtatttg aaataatttt agaagaagag gatgaaaggc cacctatact cgtaaaagaa
    21901 cctactagtg aagaatatag agtagcaagg ccgatgttaa aacaagtact ataatgaaaa
    21961 ggagacccat atgcagagag taacttcata tccgtggtcg ttaagaaaaa tatttgtctt
    22021 tttcctttgc tttattctgc ctcctatcgg tgccatttac attttgatga atagagaggc
    22081 gctacaaaag agagactaca ttttatattt attatttgct gctattaata tatcgctttg
    22141 gttatcattg atgatttttg ataggagtat gtggatggta gcggggcatg atgtgcttgg
    22201 tgtaattgtt attatttttt cgaatatgaa taagagctaa cccagcaatc ttaaagttgc
    22261 tgggttttat tttgctattt ataatgaaga aacaaatttt taatagagag tagtgatgtt
    22321 atgagatgga aagcaggaac gtttgaaaaa atagaaacga atgactcatc tgttgagaaa
    22381 attataaaca cgtttaagga acaaaactta aatggtggcg caataataag ctgttttaaa
    22441 gtacataacg aaaatttttt caaagaaata ccacattcga aagatggata cgagcacttc
    22501 tttagaagaa tcttcaactc tttagatata atacataact tagaagagtt aaaaatacat
    22561 acatcagaaa aatataaatt tcattttaaa gaacatctgg tagtcatgct tgatggtagc
    22621 attgccgctc aaattttgtg gggcggagca tatgaaggat ttaaggaacg accagttatc
    22681 gcaaaacaat tagcggtcaa tgtatgtcaa tatatgttcc aagatcgata cgaagatatt
    22741 aaagtgttcg aaagctatcg cccttggaca gattggtttt acgatgttgc gtgggatgct
    22801 acttggatgg tgttagatag taaggagcat aaaatgtggt tagtttgtgc tacggatacg
    22861 gattgataga agagggggct ttgtagaaat gctacaaggc cctttatctt ttgggaatga
    22921 atagaaaacg aatcatataa atgctatact aaaaaatgtt tgtaatgtca gtttcatact
    22981 attgtataat gctgacttac tagaaaagat aagaggagaa tgaacgtgaa aaagatacag
    23041 aaattattgc tgttaatgat ggtagtagga ttaacagtag gtgttttagc agggtgtgca
    23101 aatccgaaag atactacaaa agaattttta acagcgatac aaaaaggtga tgtagaaaag
    23161 gctcgtacat ttgttgagag tgacaaggaa tttaataaac taaatgaaaa aacagatgat
    23221 gctgaggcaa aagcgatgct gagtgcaatt acgaaaaact ttaaatttga aaagccagaa
    23281 gaagtatcga aaaaggatga caaagcagaa gtgaaagtga aaattacatc tgctgatcta
    23341 tccgttgctg taacaaaagc agtgggagaa gttatgccaa tggccttcgc tagtgctttt
    23401 agcgaagaca aagaacaatc tgaaaaagca atcgaaaaaa caatgacatc aactatcgtc
    23461 aaaaacttag cggataaaga tgcagcaatg gcaactcgcg aagttacatt gaacttaaag
    23521 aaaaacaaag atggc
//
