LOCUS       NZ_CP036118            22497 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Bacillus mycoides strain JAS481 plasmid p237.
ACCESSION   NZ_CP036118
VERSION     NZ_CP036118.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus cereus group.
REFERENCE   1  (bases 1 to 237265)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 237265)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.86x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018741645.1-RS_2024_12_12
            Annotation Date                   :: 12/12/2024 04:46:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,189
            CDSs (total)                      :: 6,036
            Genes (coding)                    :: 5,734
            CDSs (with protein)               :: 5,734
            Genes (RNA)                       :: 153
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 302
            CDSs (without protein)            :: 302
            Pseudo Genes (ambiguous residues) :: 0 of 302
            Pseudo Genes (frameshifted)       :: 122 of 302
            Pseudo Genes (incomplete)         :: 192 of 302
            Pseudo Genes (internal stop)      :: 81 of 302
            Pseudo Genes (multiple problems)  :: 78 of 302
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:51:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 117988
            Orig. end                         :: 140485
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036118.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22497
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="deazapurine"
                     /region_number="1"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /tool="antismash"
     cand_cluster    1..22497
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22497
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12497](+)"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12497
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     misc_feature    complement(756..770)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.98"
                     /tool="antismash"
     gene            1216..2250
                     /locus_tag="EXW43_RS28205"
                     /old_locus_tag="EXW43_28835"
     CDS             1216..2250
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662192.1"
                     /locus_tag="EXW43_RS28205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28835"
                     /product="bis-aminopropyl spermidine synthase family
                     protein"
                     /protein_id="WP_016127991.1"
                     /transl_table=11
                     /translation="MKENKIILLYERFIELDYEEELDKVPKLKNRGVLLNFWKKWYEIS
                     EKQFEFIIWKSINTVDTLDDLVKITGTLSLALRLLKVLKERNLVEIIENKIRFSQDLTS
                     SILYEPTSLPNTGYENKINKKKYAQFKATWDSSLRRAEIINQELSSNKNIFFCGDDDYT
                     SLALKQYKNREISVGDIDEELIEYFKHTNNDIKFYNFDVRNEVMEDLRNKYDAIHCDPI
                     DDGRGLDLWLNRANELLKGQKGDLIFLNISVKRLGNRAVYLQNFLTSLGFYLKEIIHDL
                     SSYKVAEEPYIDEELIKKDLDGIGFSKDTFHNLYIQTDMLVFVRLIDKPTLFPQEYYEI
                     RRKI"
     gene            2271..3938
                     /locus_tag="EXW43_RS28210"
                     /old_locus_tag="EXW43_28840"
     CDS             2271..3938
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289405.1"
                     /locus_tag="EXW43_RS28210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28840"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_048517101.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 2.7e-41,
                     bitscore: 136.0, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVLGVNGWDFDVHDASACLFYNGKLIAAAEEERFIRQKKALDKI
                     PYNSIAYCLKEAEITPNEVDHIVMGWDVEQLYFEKYSKNLNKDDCLEKIFPKRIFKRDK
                     NPQIHMCSHHLAHASGAFFSSGFNEATIIVIDGSGEEESITIAKGKGNIIEVLEKYPLE
                     HSLGIFYEALTVFSGLGRHNEGKLMGLSSYGEEIFEFPDILENPLKPNKNTVSMNGKYF
                     SVLKDWIKVINSITKIAPNYSKYEYNPIDSILLMNSSVMEYKNIAASGQAALERAIVKL
                     VKKAINLTGIDNLCLSGGVALNCIANRIIADLPEVDSLYIQPGASDSGVSIGAATWFLA
                     ENGITPMFTEDHVYSGPEFPDSSILNILKKYNLSYIELGSNKYDKCSELLIQNKIIGRF
                     SGKMEFGPRALGNRSIIANPQSRDMLNKVNTIKKREQWRPLAPSIIDENASVVLEEKIN
                     NPYMLLNSTVKKEVHHLVPAIVHVDGSTRAQVVTRDMNSDYYETIYNFYQKTGIPAVMN
                     TSFNVGKEPIICNPSDAIRSFYGSEMDALLLGSFLILK"
     gene            3952..4710
                     /locus_tag="EXW43_RS28215"
                     /old_locus_tag="EXW43_28845"
     CDS             3952..4710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018782256.1"
                     /locus_tag="EXW43_RS28215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28845"
                     /product="DUF5591 domain-containing protein"
                     /protein_id="WP_002191891.1"
                     /transl_table=11
                     /translation="MRNRNYSNLQDERIKDLVLNKKSYPYYPEYILLDLIKEETVFKRG
                     ACSKYIHHEEFNTWQDYFCGDYYEKPQGKRIAFLQVCSWAKPYDFSYIGKKIREVTNKY
                     PMVHPIILSNAGIIPYEYQMNPTFCAYDWMEDIEDPVIYEELMKEYRDKLIQRIRRYLE
                     SNSYDVVVQYGIPVKKYSMAPAIKDICKDLGIAFLLTPDIETYRNNKGKLVELKDSGEF
                     YCLDEVLSSMDNSLNKVSRYVESINCNTSL"
     gene            4676..5455
                     /locus_tag="EXW43_RS28220"
                     /old_locus_tag="EXW43_28850"
     CDS             4676..5455
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128555.1"
                     /locus_tag="EXW43_RS28220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28850"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_002205033.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.7e-16,
                     bitscore: 54.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNLSIVIPAYNDIRLGKCLKSIDENVEVVVVLNGATEEVKKIAY
                     SSNAVIGELPTPNLAKAYNYGIEISSKDNVLIMDSDCVFMPGTINKLFKLLDAGSLAKG
                     RVMFSFNSKIGKIIARARHIHTCKKNAYSPPLAFNKGILAKVNGYYFDENLSWTEDYDF
                     DIRVQSASLKILYDDNARIIHPELSIKQDLKSSFNYGVGHARGVLHKKNGYYEPKNKTR
                     SIINSYKYIKKKYGYLTAFYLIFWQIAFYRGYKKEIH"
     gene            5467..6267
                     /locus_tag="EXW43_RS28225"
                     /old_locus_tag="EXW43_28855"
     CDS             5467..6267
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002205032.1"
                     /locus_tag="EXW43_RS28225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28855"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_002205032.1"
                     /transl_table=11
                     /translation="MQQQYDEISELYDIIIPEPDGIFDFYSGLVKPNDEVLDLGCGTGR
                     LSFILAEKGANVTSVDISAGMIEKASKKLDEMPNIKDKIEFKVSSATDFKSERKFDFIF
                     MSGGVFEYLLTSSQQKLALRNIKLLLKEGGIFVFDIITPPTILPYSKRVSDGGNSPIKG
                     ENFKNYKVKSWDVVKADHYKQIIETTCYFEVYDIADNFLSEKKFRFLSKYTLPSEMQYL
                     LEIEGFNIKNFHGDYNKNPFGRNSEFMVYECRKQGENFNDIQCE"
     misc_feature    complement(6346..6359)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.71"
                     /tool="antismash"
     misc_feature    6361..6380
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 20.52"
                     /tool="antismash"
     gene            6737..7393
                     /locus_tag="EXW43_RS28230"
                     /old_locus_tag="EXW43_28865"
     CDS             6737..7393
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002090560.1"
                     /locus_tag="EXW43_RS28230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28865"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_002205031.1"
                     /sec_met_domain="PIG-L (E-value: 5.7e-26, bitscore: 85.7,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDIVKKHLVIAPHHDDEVIGCGGTIAQAISKGEHIKVIIITKGD
                     LSGGVGDLNEIISNRENECINACNTLGIEKGNVKFLKKPDRSLVYSLDFVEEIIHEISI
                     YKPNFIYFPHDMESDRDHRIVNEVVSEAIFLCQSGFLKENCAPMCLQYEVWTPMKNYQV
                     VKDITRFIELKKASIKKYESQLKTLNLVDGVLGLNSYRGMQAGVQFAEVFRVVSK"
     gene            7411..8409
                     /locus_tag="EXW43_RS28235"
                     /old_locus_tag="EXW43_28870"
     CDS             7411..8409
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006097705.1"
                     /locus_tag="EXW43_RS28235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28870"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_016127989.1"
                     /transl_table=11
                     /translation="MDIIEIENVSKTFERVKIEEGLINSFKSLFKREKVKVTALSDVSF
                     KIKEGKIIGLIGANGAGKSTLMKAMVGLIKPTSGRILVNGFNPHDKKKDFLKSIGVVLG
                     QKNQLWWDLSPYETFLLHKEIYELSDTEFRKNVDELAKNLGVSEILKSPVRNLSLGERM
                     KCELIASILHSPKILFLDEPTIGLDFLAQKNIRNFLKNYCKERNTTVVITSHYFPDIYE
                     LCEELIILKNGEVVFNNNFKKIKEEIKSYKYIYLSFENEINSQDLKKYGEVKESDKFSV
                     TIKVQDKLVNETISSILKEFNVIDYNLTEMSSQDLIEDIYSMESTGVKITV"
     gene            8406..9197
                     /locus_tag="EXW43_RS28240"
                     /old_locus_tag="EXW43_28875"
     CDS             8406..9197
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018782253.1"
                     /locus_tag="EXW43_RS28240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28875"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_000760370.1"
                     /transl_table=11
                     /translation="MKKYLKPMMLSFQAVFQYRMNVVLYMIFGLIPLVALILLWHSLFE
                     TQSNIQGYTLEMMITYVIIAKLIELLLIPEMHWSINEEIQSGELSKYLIKPFSYFGYWF
                     SHNLGNKIIHLLMSVIPIIPIIFLNRDYFLLPTLKYTFLFILSIVGALILYYMIYYLIS
                     LFSFYFVEISSFFFTVDIVLELLSGSLIPLEFLPAPLNTITQFLPFSYLIHFPVNVYLG
                     NLSGTEIVNGLISQVIWSLVFYVLIRVLWKKGLNKYESVGA"
     gene            9200..9988
                     /locus_tag="EXW43_RS28245"
                     /old_locus_tag="EXW43_28880"
     CDS             9200..9988
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003203745.1"
                     /locus_tag="EXW43_RS28245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28880"
                     /product="ABC transporter permease"
                     /protein_id="WP_002191888.1"
                     /transl_table=11
                     /translation="MIRYLKMLKAILKINLSNIMMYRVNFFLNILDSVVWFIVTLVFFN
                     SIFDSFGNINGWNTNDIYLLIGTSELIKSLMFTLFINNLPYIPSLVNQGSLDQILFKPI
                     NSQFLVSLRKLDLGNLGNCLPAVLLISYALLQKGESVSIVNGFSFLGLLFLGIILSYSL
                     WFILMTLSIWLTKVEGMHELFLGTMTLLRYPSSLYKGISRFVFLFVFPIVIVSNIPTYA
                     LIGRLELNDVFALMGYSIGFFIISIYFWKFALRYYNSASS"
     gene            10001..10666
                     /gene="queC"
                     /locus_tag="EXW43_RS28250"
                     /old_locus_tag="EXW43_28885"
     CDS             10001..10666
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287172.1"
                     /locus_tag="EXW43_RS28250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28885"
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_002205029.1"
                     /sec_met_domain="QueC (E-value: 1.2e-86, bitscore: 283.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSNDKAIVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKFE
                     IDCAAAIANELGIKHTVIDMSLLNQLAPNALTRKDMEITHEEGELPSTFVDGRNLLFLS
                     FAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWID
                     KAETWKLSDELGAFEFVREKTLTCYNGIIGDGCDECPACQLRKTGLDTYLQEREGGNE"
     gene            10666..11157
                     /gene="queD"
                     /locus_tag="EXW43_RS28255"
                     /old_locus_tag="EXW43_28890"
     CDS             10666..11157
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368418.1"
                     /locus_tag="EXW43_RS28255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28890"
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="WP_000426941.1"
                     /sec_met_domain="PTPS (E-value: 3e-37, bitscore: 121.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFFGFRIVENLQKMDKDIQREQLKYHNKRVMVSKEFTFDAAHH
                     LHCYEGKCKNLHGHTYKVVFGISGYVNDIGLAIDFGDIKEIWKNEIEIYLDHRYLNETL
                     PVMNTTAENMVVWIYEKMAEALTKGNRAEEYKGARVEFVRLFETPTSYAEVRREWILDE
                     "
     gene            11150..11866
                     /gene="queE"
                     /locus_tag="EXW43_RS28260"
                     /old_locus_tag="EXW43_28895"
     CDS             11150..11866
                     /EC_number="4.3.99.3"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="queE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036298.1"
                     /locus_tag="EXW43_RS28260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28895"
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_002205028.1"
                     /sec_met_domain="QueE (E-value: 6.5e-58, bitscore: 189.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.2e-12, bitscore: 40.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.1e-14, bitscore: 47.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIPVLEIFGPTIQGEGMVIGQKTMFIRTAGCDYSCSWCDSAFT
                     WDGSAKEQVRQMAPEEIWNELVEIGGENFSHVTISGGNPVLLKNIQFLLTVLKENGIRT
                     AIETQGSKWQEWLLQIEEVTISPKPPSSKMKTDFTMLDSVIHKLERKDFSLKVVVFEDY
                     DFEYAVKVHKRYPQVPFFLQVGNDDTKTVDDAVLIKNLLQKYERLIEKAVQCKEMNDAK
                     VLPQLHALVWGNKRGV"
     gene            11910..12497
                     /gene="folE"
                     /locus_tag="EXW43_RS28265"
                     /old_locus_tag="EXW43_28900"
     CDS             11910..12497
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054143.1"
                     /locus_tag="EXW43_RS28265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28900"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_000054143.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 3.2e-77,
                     bitscore: 251.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKTIQSVEIDTDKIEVAVKMILEAIGEDINREGILETPKRVAK
                     MYKEVFQGLGQNPSEHLLKIFNENHEELVLVKEIPFYSMCEHHLVPFFGRAHIGYIPNN
                     GKVTGLSKLARALETICKRPQLQERITNELANVIFETLEPKGVIVVIEAEHMCMTMRGV
                     KKPGSMTITSSYKGIFKDNSTLRSETLNLIER"
     gene            12775..12942
                     /locus_tag="EXW43_RS28270"
     CDS             12775..12942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018767682.1"
                     /locus_tag="EXW43_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002205027.1"
                     /transl_table=11
                     /translation="MISSYSVRYILITGNIFIKKVITVYASSAFFAIEKIKKELERRFS
                     NPTKIEVYAV"
     misc_feature    12821..12834
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     gene            complement(13031..14191)
                     /locus_tag="EXW43_RS28275"
                     /old_locus_tag="EXW43_28905"
     CDS             complement(13031..14191)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783621.1"
                     /locus_tag="EXW43_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28905"
                     /product="site-specific integrase"
                     /protein_id="WP_048517102.1"
                     /transl_table=11
                     /translation="MKFELITIHSETSLENIEKQKQNFANIIALWNRDYINEAEFKKEN
                     NEREDSYTYEGFSDEEILYYYLNRQTHFDQEKRIKDASRTLYARDLSQFYFFIKQSTEF
                     LQQDVKDYVIGQVWRNLRKRHIRNYQKWLSQEAISYQSKEKYKASTISRKLGVIRSYLK
                     WLYEIQYIQEPLHVEILSTTVNKQHKPKRELSYEEVKHLLHYYKDNEINYALLSVLATT
                     GLRVAEVAHAKWEDLEYDAIRGRYYLTVDTKGDNERIVSINKDIFNRIVAFRIRRRLPV
                     NIGTKNGGTIFQTKNHTAYRENYLSQYISKIIKDTKLLFTENIRITPHFFRHFYVQYLY
                     DYKGLAPHVIAAAVGHKNDRTTKENYLKQRLTKDNDVGNLIGDDEF"
     gene            14550..15533
                     /locus_tag="EXW43_RS28280"
                     /old_locus_tag="EXW43_28910"
     CDS             14550..15533
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462941.1"
                     /locus_tag="EXW43_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28910"
                     /product="DNA-binding protein"
                     /protein_id="WP_215576256.1"
                     /transl_table=11
                     /translation="MFERQEMNMNTNEVKAYLGISSFIFTTLIKQGQLNPINRETWRLD
                     GSFLFKREDIEKLKEDRETEGITLYQAAKDYNVSMYQLEKWIEQGDLTCTIQKHRNRET
                     KFVHEEEINGLVQQLDQTNTLYTFSQKYNVVLFQKFMEGNKLARIISIPKRGDIVLIDE
                     FGNNMTLEDAIKVGYKPAYLLSDKPRSHHQKFVKFRFPKSNQLRSNIFHLIDLVLQYVS
                     PRNIKVSEEDGFWYFDVRQSIIQLPMQMQIEWIDCLTPYIIEGKLTRRVNNSVYLDSSS
                     VTKAVTITSNEYHAITKIVNETNSSIEEFIASAIREKINDYQASHN"
     gene            15581..15835
                     /locus_tag="EXW43_RS28285"
                     /old_locus_tag="EXW43_28915"
     CDS             15581..15835
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127984.1"
                     /locus_tag="EXW43_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28915"
                     /product="NUMOD4 domain-containing protein"
                     /protein_id="WP_087963197.1"
                     /transl_table=11
                     /translation="MEETWFDIKGYEGIYQVSNVGRFRSLDRIGQTGKFLKGKIKVRNG
                     DPYGFKTIKLYKDGKPKNHNVAEIIKNTFPEGIKKSYWS"
     gene            complement(15901..16607)
                     /locus_tag="EXW43_RS28290"
                     /old_locus_tag="EXW43_28920"
                     /pseudo=""
     CDS             complement(15901..16607)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012259872.1"
                     /locus_tag="EXW43_RS28290"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28920"
                     /product="IS6 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEKQNLFKWKHYQPDIILLTVRWYLRYNLSFRNLVEMMEERGLSL
                     AHTTIMRWVHQYAPELDKRVRRHLKSTNDSWRVDETYVKIKGQWMYLYRAVDSKGNTID
                     FYLRKTRDHRAAKRFFKKALQSFHVSKPRVITVDKNPAYPIAIGELKKEKKCL"
     gene            complement(16947..17855)
                     /locus_tag="EXW43_RS28295"
                     /old_locus_tag="EXW43_28930"
     CDS             complement(16947..17855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002166573.1"
                     /locus_tag="EXW43_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28930"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_002192079.1"
                     /transl_table=11
                     /translation="MSNSLVNLRIDFAFKQLFGTNGNEDILVAFLNAILKDSLESPIVS
                     LQLEDPHLHREYEEDKLSILDISATLNTGTKVNVEIQLNNNHDMIKRSLYYWGRLYTSQ
                     LQKGMPYSSLHKTITINLLNFVMFPEYEAFHTTGILWNQQQQKLLSDDIEVHIVEIPKL
                     LQQWREEKVNPWEDSFVRWLLLLPANEDEYLTQTLEDIAMNQDPILQKAMNKWERMSQD
                     SSFRQAYEAREKALMDEAAKFAHARNEGKKEGIQEGVQQGVQQGKIQMIKGMHELGVPL
                     ETIAKASKLGIDEIERILEQK"
     misc_feature    17999..18013
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    18199..18213
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.67"
                     /tool="antismash"
     gene            18241..19613
                     /locus_tag="EXW43_RS28300"
                     /old_locus_tag="EXW43_28935"
                     /pseudo=""
     CDS             18241..19613
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016112520.1"
                     /locus_tag="EXW43_RS28300"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28935"
                     /product="amino acid permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNLFRKKSISALLAQSEQKEASLKKELGAFDLTMLGIGVIIGTGI
                     FVLTGVAAAEHAGPALVLSFILSGLACVFAALCYSEFSSTVPVSGSAYTYSYATFGELI
                     AWILGWDLILEYGLASSAVASGWSGYLQGLLSGFGITLPTALTSAYSPEAGTYVDLPVI
                     CIIFLMTLLLTRGAKKSACFNAIMVAIKLFVILLFIVVGAFYVKPENWTPFMPFGFSGV
                     TTGAATVFFTYIGFDAVSTAAEEVKNPQRNMPIGIIASLTICTILYIVVSLILTGIVPY
                     DQLGVKNPVAFALQYIQQDWIAGFISLGAITGITTVLLVMLYGQTRLFYAISRDGLLPK
                     ALSRVNKKTKTPVINSWITATMVAFFAGFVPYSHSALYQLE"
     misc_feature    complement(19960..19973)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.77"
                     /tool="antismash"
     gene            20225..20662
                     /locus_tag="EXW43_RS28305"
                     /old_locus_tag="EXW43_28940"
     CDS             20225..20662
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016718145.1"
                     /locus_tag="EXW43_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28940"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_070143925.1"
                     /transl_table=11
                     /translation="MIREAEPKDSNVIENLYKKLAPHSKNIKVLPERIEQIRNDSNNFL
                     FVYEEDCKVKGSIFMTFCLDPGYQFRPYTVLEYVIVNEDFRGNGIGEKLLKHVERLSIA
                     RGSTRIILLSSTTRIEAHKFFSKNGYNGTISKGFKKYIPIN"
     gene            20999..21565
                     /locus_tag="EXW43_RS28310"
                     /old_locus_tag="EXW43_28945"
     CDS             20999..21565
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002205020.1"
                     /locus_tag="EXW43_RS28310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_28945"
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="WP_087963259.1"
                     /transl_table=11
                     /translation="MKCYQLHLELVECPFPIWRRVSLPTDLSFDDLHDVIQCLFQWQHQ
                     HLFEFTVGKYVISSPPDPSISFHTLAMTTSSPMLHADKTMLHQHIGKTDQAFQYVYDFG
                     DHWLLQIHVEKIFDQPSDEIKCIGGENAAPLEDIGGIPGYIEFLEAIKDSSHPQHKIYA
                     EWDLLNFDPSFFDIHEINKGLTYCD"
ORIGIN
        1 tttaatcata tgcatggctt ctactccaga aagaatggat gtagctgtgt caaaacattt
       61 gaaccctagc atggaacgga ttcgcttctt tataaagcga tgatcttgtt ctactatgtt
      121 attcaagtac ttttgttgtc taagttgcat accatcaggt atgctttttt ctttttttaa
      181 ctgttcaatt gctataggat aagcggggtt cttatcgact gttataacac gtggctttga
      241 aacatgaaaa gaccgcaaag ctttcttgaa aaagcgcttt gctgccttct gatctcttgt
      301 tttgtttagg aaaaaatcaa ttgtgtttcc tttcgaatca acagcacgat acagatacat
      361 ccattgacct tttactttga tatatgcttc atcgactctc caagaatcat ttgtttgttt
      421 gaggtgacga cggattcgtt tgtccaattc aggaccatac tgatgaaccc aacgcataat
      481 cgttgtatga gaaatggata aaccccgttc ttctagcatt tccaccaaat cacgaaaact
      541 gagattgtac cgtaggtacc atcttaccgt taacaaaata atatcaggct gataatgctt
      601 ccatttgaat acattttcct tttccatacc aatcacgcac cctttttaaa gtaatagtaa
      661 cagtatgtcc aagatttata gattcattgc aattgtcctt aagtttttgc atcagaaccc
      721 aaaatagacc tcccccaata acccccgaaa ataaacattt tttgaaaaat ttataaaaag
      781 gaaaatcgac aaaaatctct aaaaaaaggc tctatactag gttttttgaa aatcctaata
      841 taaaaattaa aataatataa atacccataa ttattcctag tattgtttta tcaggaaaaa
      901 ttttacttaa ttttctgatt aaattttatc tacaaatata atttatttat taatcagaaa
      961 attctacttt tatgctaata ttggtggtgc agctctgttg caaatatttg aattacacaa
     1021 ttatctatat aagggggaat gtgaaatgga aaaggaatat attcatgaag aaatgctaga
     1081 gcttgaagat cttgaattag atgaagagga tttactaatt cgtgcaggca agacattagg
     1141 ttaagtttta aaataaggag gttacatatg cagtttaact gtatatgtaa ctttttttaa
     1201 ggtagggtat acagtatgaa agaaaataag attattttat tatatgaaag atttattgaa
     1261 ttagactatg aagaagagtt agataaagta ccaaaattaa aaaatagagg ggtacttttg
     1321 aatttttgga aaaaatggta tgaaattagt gaaaaacaat tcgaatttat aatttggaag
     1381 tccattaata ctgtagatac tttagatgat ctagtcaaaa taactgggac tttaagtttg
     1441 gctttaagat tattaaaagt attaaaagaa agaaatttag ttgaaattat agaaaataaa
     1501 ataaggtttt cacaagattt aacaagtagt attttatatg aaccaacctc tcttcctaat
     1561 acaggatatg agaataaaat aaacaaaaaa aaatatgctc aatttaaagc tacttgggat
     1621 agttcgttga ggagagctga aataataaat caagagttat catctaataa aaatatcttt
     1681 ttttgcggag atgatgatta tacaagtttg gcccttaaac aatataaaaa cagagaaata
     1741 agtgtaggag atattgatga agaactgatt gaatatttta aacatacaaa caatgatatt
     1801 aagttttata attttgatgt tagaaatgaa gttatggaag atttaaggaa taagtatgat
     1861 gcaatacatt gtgaccctat agatgatggt agagggttag atttgtggtt aaatagagct
     1921 aatgaattat taaaaggtca aaagggtgat ttaatttttt taaatataag tgttaaaaga
     1981 ttaggtaata gggcggttta tttgcagaat ttcttgacat ctttaggttt ttatttaaaa
     2041 gaaattattc acgatttaag ttcttataaa gtggctgaag agccttacat tgatgaagaa
     2101 ttaataaaaa aggacttaga tggcattggt ttttctaaag atacattcca taatttgtat
     2161 attcaaacag atatgttagt ttttgtacga ttaatagata aaccaaccct ttttccgcaa
     2221 gaatattatg agattagaag aaaaatataa aataactgcg aggtaatata atgtatgttt
     2281 taggagtcaa tgggtgggac tttgatgttc atgatgcaag tgcgtgttta ttttataatg
     2341 gtaaattaat agctgcagct gaagaagaaa gatttattcg tcaaaaaaag gcattagata
     2401 aaattccata taattcaata gcttattgtt taaaggaagc tgaaattact ccaaatgaag
     2461 tagatcatat tgttatgggc tgggatgtag aacaattata ttttgagaag tattcaaaga
     2521 atcttaacaa agatgattgt cttgaaaaaa tttttccgaa gagaattttt aagagagata
     2581 aaaatcctca aattcatatg tgttctcatc atttggcaca tgcttctggt gcgttcttta
     2641 gttcgggatt caatgaagct accataatag ttattgatgg aagtggagaa gaagagtcaa
     2701 taacgatagc aaaaggaaaa ggtaatataa tagaagtact agaaaaatac ccgttggaac
     2761 attctttagg tattttttat gaagcattaa ctgtattttc aggtttaggg aggcataatg
     2821 aagggaagtt aatgggccta tcttcatatg gagaagaaat atttgaattt cctgatatac
     2881 tggaaaatcc tttgaaacca aataaaaata cagttagtat gaatggtaaa tatttttcgg
     2941 tattaaaaga ttggataaaa gttattaata gtataacaaa gatagctcct aattatagta
     3001 aatatgaata taatccaata gattcaatac tattaatgaa ttcatcagta atggagtata
     3061 aaaatattgc agcctcaggt caggcagcct tggaaagagc aattgttaag cttgtaaaaa
     3121 aagctattaa tctaactgga atagataatt tgtgtctttc gggaggagta gcattaaatt
     3181 gtatagcgaa tagaattata gctgatttac cagaagtgga tagtttgtac attcaaccag
     3241 gtgcttcaga tagtggggta agtattggag cagctacatg gtttcttgcc gaaaatggta
     3301 taacgcctat gttcactgaa gatcatgtat attctggtcc ggaatttcct gattctagta
     3361 tcttaaatat attaaaaaaa tataatctat catatataga attaggttct aataaatatg
     3421 ataaatgctc cgagttatta attcagaata agataatagg aagattttct ggaaagatgg
     3481 aattcggtcc tagagcttta ggaaatagaa gcataatagc taaccctcag agtagggata
     3541 tgttaaataa agtaaatacc attaagaaaa gagagcaatg gagaccattg gctcctagca
     3601 tcatagatga aaacgcttct gtagtattag aagaaaaaat aaataaccct tatatgctgt
     3661 taaattctac tgttaaaaaa gaggtacatc atttagttcc agcaatagtt catgttgatg
     3721 gatcaacaag ggctcaagta gttacgaggg atatgaattc tgattattat gaaacaatct
     3781 ataactttta ccagaaaaca ggaattcctg cagttatgaa tacatcgttt aatgtaggaa
     3841 aagaaccaat tatatgtaac ccaagtgatg ctattaggtc attttatgga tcagagatgg
     3901 atgccctttt attaggttca tttttgattc ttaaataaag gaggagagat tttgagaaat
     3961 agaaattatt ctaatctaca ggatgaaagg ataaaggatt tggtacttaa taaaaaaagt
     4021 tatccttact acccagaata tatactatta gatttaataa aagaggaaac agtttttaaa
     4081 cgaggagctt gctcaaagta tattcatcat gaagagttca atacatggca ggactatttt
     4141 tgtggggatt attacgaaaa gcctcagggg aaaagaattg cttttttaca agtttgttct
     4201 tgggctaaac catatgactt ttcatatatt ggtaaaaaaa ttagagaagt tacaaataaa
     4261 tacccaatgg ttcatccaat tattctatca aatgcgggaa ttataccata tgaataccaa
     4321 atgaatccta ctttttgtgc gtacgattgg atggaagata ttgaggatcc agtaatttat
     4381 gaagaattaa tgaaagaata tagggataaa ttgatacaaa gaattaggag atacctagaa
     4441 tcaaattcat acgatgtagt agtacaatat ggtataccgg taaaaaaata ttcaatggct
     4501 cctgcaatta aagatatttg taaggatcta ggaattgctt ttcttttaac cccagatata
     4561 gaaacatata gaaataataa aggtaaatta gtcgagttaa aggattcagg agaattttat
     4621 tgtttagatg aagttttgag tagtatggat aattctttaa ataaggtgag tagatatgtt
     4681 gaatctatca attgtaatac cagcttataa cgatatcaga ttgggaaagt gtttaaaaag
     4741 tattgatgaa aatgtagagg ttgtcgttgt cttaaatggt gcaacagaag aagtaaaaaa
     4801 aatcgcctat tctagcaatg cagtaattgg ggaattacct acacctaatt tagcaaaagc
     4861 ttataattat ggaattgaaa tttctagtaa agataatgtg ttaattatgg attcagattg
     4921 tgtttttatg ccaggtacca tcaataaatt attcaaatta ttagatgcag gatctttggc
     4981 taaaggaagg gtgatgtttt cctttaacag caaaattgga aaaatcattg cacgtgcaag
     5041 acatatacat acttgcaaaa aaaatgcata ttcacctcca ttggcattta ataaaggaat
     5101 cttagcgaag gtaaatggat attattttga tgagaattta tcttggacag aggattatga
     5161 ttttgatatt agagttcaat ctgcaagtct taagatttta tatgatgata atgcaagaat
     5221 tattcatcca gagttaagca ttaagcaaga tttgaaaagt tcatttaatt atggggtagg
     5281 tcatgcacgt ggggttttac acaaaaaaaa tggttattat gaacctaaaa ataaaacgag
     5341 gtcgattatt aactcatata agtatatcaa aaaaaaatac ggttatttaa ctgctttcta
     5401 tctcatattt tggcagattg ccttttatag gggatataaa aaagaaatac attaaggagg
     5461 aaaacaatgc agcaacaata tgatgaaatt tctgaattat acgacattat catcccagaa
     5521 cctgatggta tttttgattt ttacagtggt ttggtaaaac caaatgatga agttttagat
     5581 ttggggtgcg gtactggtag attatctttt attctcgctg aaaaaggcgc taatgtaact
     5641 agtgttgata tatcagcagg aatgattgaa aaagctagta agaagttaga tgagatgcca
     5701 aatattaagg ataaaataga atttaaggtt tcttctgcta cagattttaa gtctgaaaga
     5761 aaatttgatt ttatatttat gtctggtggt gtatttgaat atttacttac atcgtcacaa
     5821 caaaaattag ctcttagaaa tattaaatta ctattaaaag aaggcgggat ttttgttttc
     5881 gatattatta cacctccaac tattcttcct tattctaaga gagtgagtga tggaggaaat
     5941 agtcctatta aaggggagaa ttttaaaaat tataaagtta aatcatggga tgtcgtaaaa
     6001 gcagatcatt ataagcaaat aattgaaacc acttgttatt ttgaggttta tgacatagca
     6061 gataatttct taagtgaaaa aaaattcaga ttcctttcaa aatatacttt accatccgaa
     6121 atgcagtatc tcttagaaat agaaggattc aatataaaaa attttcatgg tgattacaat
     6181 aaaaatcctt ttgggaggaa tagtgaattt atggtttatg aatgtaggaa gcaaggggaa
     6241 aattttaatg atatacagtg cgaatagacg ctcgtgaact actcgccact tagcaaagct
     6301 tgaagtggga gcttctcagt tccacgacga aagtaacctt tcgtctccct gagcgttact
     6361 tcggggtgtt ccacccctag atgtccaacg cttggacgct ctcttggtac ggttgatatt
     6421 ttacgcagga accgaatggc ttggttttca cactctattt tcttcctgca acctcctata
     6481 tcaagttatc aaagaacttc atatagctag tttatcaaaa gtttttggct atgccaaacc
     6541 aaaattcatc tcccacctac agttgggcta tcgcccttca cacgcttgag gaaggagaat
     6601 tctttcggta aattcgttaa aaaagtatat ttttctagtg gaaataaaat gtatccagtt
     6661 agtatactcc agagtaaata atttttaatt aaaataatag gtaaatgatt tacctgttca
     6721 ataaaggtga tgctgaatga aggatatagt aaaaaaacat ttagttatag cgccacacca
     6781 tgacgatgaa gtcattggct gtggtggaac aattgctcaa gctattagta agggtgaaca
     6841 tataaaagta ataataatta caaaaggaga tttatctgga ggtgtagggg atttaaatga
     6901 aattatttca aatagagaga acgagtgtat aaatgcttgt aatacattag ggatagaaaa
     6961 aggaaatgtt aaatttttaa agaaaccaga cagatcactt gtgtattctt tagattttgt
     7021 ggaagaaatt attcacgaaa tctctatata taagcctaat tttatttatt tcccccatga
     7081 tatggaaagt gatagggatc atcgaatagt aaatgaagtt gtatcagaag caatattcct
     7141 gtgtcaatca gggttcttaa aagagaattg tgctccgatg tgtttacagt atgaagtatg
     7201 gactcccatg aaaaactatc aggttgtaaa agatattacc aggtttattg aactgaaaaa
     7261 agcatcaatt aaaaaatatg aatcccaact taaaacatta aatttggttg atggagtttt
     7321 ggggctaaat tcttataggg gtatgcaggc aggagtgcaa tttgcagaag tttttagagt
     7381 ggtaagtaag tagtaaaaag gagagagaag atggatatca ttgaaattga aaatgtatca
     7441 aaaacttttg aaagagtaaa aattgaagaa ggattaataa actctttcaa gagtttattt
     7501 aaaagagaaa aggtcaaggt tactgcttta agtgatgtgt cattcaaaat aaaagaaggt
     7561 aaaataatag ggcttattgg cgcgaatggt gctggtaagt ctaccttaat gaaagcaatg
     7621 gttgggttaa ttaaaccaac ttccgggaga attttggtaa atggatttaa cccccatgat
     7681 aagaagaaag attttttaaa gtcaattggc gttgttttag gacaaaaaaa tcagctatgg
     7741 tgggatcttt ccccttacga aacattttta ttacataaag aaatatatga actgtctgat
     7801 acagagttta gaaagaatgt agatgaatta gctaaaaatc ttggggtatc agaaattctt
     7861 aaatcgccag taaggaatct atcgttagga gagagaatga aatgtgagtt aattgcttca
     7921 atcttacact cacctaagat attattttta gatgaaccga ctattggatt ggattttctt
     7981 gctcaaaaga atattagaaa ttttctcaag aattattgca aagaaagaaa tacaacagtt
     8041 gtaataacta gccattattt cccggatata tatgagttat gtgaagaatt aataatattg
     8101 aagaatggag aagttgtttt taataacaat ttcaaaaaaa taaaagaaga aattaagagt
     8161 tataaatata tatatcttag ctttgaaaat gaaataaatt ctcaagatct taagaaatat
     8221 ggagaagtta aagaatcgga taaatttagt gtaacaataa aagttcaaga taagttagtg
     8281 aacgagacca tatctagcat attaaaagaa ttcaatgtta ttgactacaa tttgactgaa
     8341 atgtcatcac aagacctcat tgaagatatt tattcaatgg aatcgactgg agtgaaaata
     8401 acagtatgaa gaagtattta aaaccaatga tgctttcatt tcaagcggtt tttcagtatc
     8461 gtatgaatgt tgtattatat atgatttttg gtttaatacc gcttgtggct ttaatactat
     8521 tgtggcattc tctctttgaa acacaaagca atattcaagg ttatactctt gaaatgatga
     8581 ttacttatgt aataattgct aagttaattg aacttttact aattcctgaa atgcactggt
     8641 cgataaatga ggaaatacaa tccggtgaat tatcaaaata tcttataaaa ccattttcat
     8701 attttggata ttggtttagt cataatttag gtaacaaaat tattcattta ctgatgtcag
     8761 tgataccgat aataccgata atattcctga acagggatta ttttcttttg cctactttaa
     8821 aatatacttt ccttttcatt ctttcaatag taggagcatt aatactatat tatatgattt
     8881 attatttgat atcactcttc tcattttact ttgtagagat atcatccttt ttctttactg
     8941 tagatatagt attagaatta ttatctggat cgcttattcc gcttgaattt ttaccagctc
     9001 cgttaaatac aataactcag tttttacctt tttcatactt aattcacttt ccggtaaatg
     9061 tatatttagg aaatttaagt ggcactgaaa ttgtaaatgg attaatttca caagtgatat
     9121 ggtctttagt tttctatgtc cttattagag tactttggaa gaaggggtta aataaatatg
     9181 aatctgttgg tgcataaata tgattagata tttaaaaatg ttaaaagcaa ttcttaaaat
     9241 taatttaagt aatattatga tgtatagagt taactttttt ttaaatatat tagatagcgt
     9301 tgtttggttc attgttacat tagtattttt taatagtata tttgatagtt ttggtaatat
     9361 taatggttgg aatacaaatg atatttattt gttaattgga acaagtgagt tgataaaatc
     9421 tttgatgttt actcttttta ttaataatct accgtatata ccgagtttag ttaaccaagg
     9481 aagtttagat cagatattgt ttaaacctat taatagtcag tttctagttt cattaagaaa
     9541 gcttgattta gggaatttag ggaactgttt accagccgtg ctgttaatta gttatgcatt
     9601 attacaaaag ggagagagtg ttagtattgt aaatggattt tctttcttgg gtctattgtt
     9661 tttagggatt atactctcgt attctctgtg gtttatttta atgactttat ctatatggtt
     9721 aaccaaagtt gaaggtatgc atgagttatt tcttggtact atgacattac ttagataccc
     9781 atcttcctta tataaaggta taagtcgatt tgttttttta tttgtttttc ctattgttat
     9841 tgttagtaat attccaactt atgctttaat tggtcgatta gaactaaacg atgtattcgc
     9901 gttaatgggt tattctattg gattttttat tatttcaatt tatttttgga agtttgcctt
     9961 aagatattat aacagtgcaa gtagttaagg ggagaataaa atgtactcta atgataaagc
    10021 aatagttgtt tttagtggtg gacaagatag cacaacatgt ttattttggg caatgcaaca
    10081 gtttgcggag gtggaagctg taacatttaa ctacaatcaa cgtcataagt tcgaaattga
    10141 ttgtgcagcg gcaattgcga acgaacttgg cattaaacat acagtgatag atatgagcct
    10201 actaaatcag ctagctccaa atgcgttaac aagaaaagat atggagatta cacacgaaga
    10261 gggtgaatta ccatcgacat ttgtagatgg tcggaattta ctattcttat catttgctgc
    10321 tgtattagca aaacaagttg gagcacgtca tattgtaacg ggtgtatgtg aaactgattt
    10381 tagtggttat ccagattgcc gtgacgtgtt tgtaaaatcg ttaaacgtta cattaaattt
    10441 atccatggat tatccgtttg tcattcacac accacttatg tggattgata aagcagagac
    10501 gtggaaatta tctgatgaac ttggagcatt cgagtttgtt agagaaaaaa cattaacttg
    10561 ttataacgga atcattggtg atggttgcga tgaatgtcca gcatgtcaac ttcgtaaaac
    10621 aggattagat acgtacctac aagaacgcga aggagggaat gaataatgga aaactttttc
    10681 ggatttcgca ttgtagaaaa tttgcaaaaa atggacaagg atattcagcg tgagcaatta
    10741 aaataccata ataaaagagt aatggtcagc aaggaattta catttgatgc agcacaccat
    10801 ttgcactgtt atgaagggaa atgcaaaaat ttacatggtc atacatacaa agttgtattt
    10861 ggtattagtg gatatgtaaa tgacattgga cttgcaattg actttggaga tataaaagaa
    10921 atttggaaaa acgaaataga gatttatttg gatcatcgct atttaaatga gacattacca
    10981 gtgatgaata cgactgcgga aaatatggtt gtttggattt atgaaaagat ggcggaagca
    11041 ttaacaaaag ggaatcgagc agaagaatat aaaggagctc gtgtcgaatt cgtacgtctc
    11101 tttgaaacac caacgagtta tgcagaagta agacgggagt ggatactcga tgagtaagat
    11161 tcctgtgttg gagatatttg gcccaaccat tcaaggagaa ggaatggtta tcggacaaaa
    11221 aacgatgttc attcgcacag caggttgtga ctatagctgc tcttggtgcg attcagcctt
    11281 tacatgggat ggctcagcaa aagaacaagt tagacaaatg gcgccagaag aaatttggaa
    11341 tgaacttgtt gaaattggtg gagaaaattt ttctcacgtt acaatttcag gtgggaatcc
    11401 cgttttgctg aaaaatattc agtttcttct tactgtatta aaagagaatg gaattcgtac
    11461 agcgattgag acgcaaggga gtaagtggca agaatggtta cttcaaattg aagaagtgac
    11521 aatttcgcct aaaccaccaa gttcgaagat gaaaacagat tttacgatgc tagattctgt
    11581 tattcataaa ttagaaagaa aagattttag tttaaaagta gttgtatttg aagattacga
    11641 ttttgaatat gcagtaaagg tgcacaagcg atatccgcaa gtaccatttt tcttacaagt
    11701 tgggaacgat gatacgaaaa cggtggatga tgcagtgctt attaaaaact tattacagaa
    11761 atatgaacgg ttgattgaaa aagctgtaca gtgtaaagaa atgaatgatg caaaagtatt
    11821 acctcaactt catgctttag tatggggaaa taaacgaggc gtataaataa gagcatttta
    11881 tgaataaatt gataaggtgg aaataatata tgagcttaaa aacaatccaa agtgtagaaa
    11941 tagatactga caaaattgaa gtagcagtaa aaatgattct tgaagcaatt ggagaagata
    12001 ttaataggga aggtattttg gaaaccccaa agcgagtagc aaaaatgtat aaggaagttt
    12061 ttcaaggttt aggtcaaaac ccttctgaac atttgttaaa aatatttaat gaaaatcatg
    12121 aagaattggt attagttaaa gaaattccgt tctattctat gtgtgaacat catttggtac
    12181 ctttttttgg aagagcccac ataggttata ttcctaataa tggaaaagta actgggttaa
    12241 gcaaattagc tagagcttta gaaaccatat gcaaaaggcc acagttgcag gaaagaataa
    12301 ccaatgaatt agcaaatgta atttttgaaa ctttagagcc aaaaggagta attgtagtaa
    12361 ttgaagctga gcatatgtgt atgacaatga gaggtgtgaa aaaacctggt tcaatgacta
    12421 taacttcgtc atataaagga atatttaaag ataatagtac acttcgaagt gaaactttaa
    12481 atttaataga gagatagaat tatatcgata ttatgctaaa aaagaacata caaaacctat
    12541 gttaaataca aacttgtatt ctattcatga gcaaacgtat agaagaaagt agacgctcat
    12601 tatcctagta cgtctaatcg aaaggcattg ctgaagactt tggcagtgct ttttctaaat
    12661 caactttttg atatttttca ttctgctcac aatatcactt tacatttttt gagaatatat
    12721 ccacacctat cggcatatat cttaaacaca atagatatat gaaagggtga gagtatgatt
    12781 tcatcatatt cagtaagata cattttaata acaggtaata tttttataaa aaaagtgatt
    12841 actgtatatg catcttcagc tttctttgcg attgaaaaaa tcaaaaaaga attagaacgc
    12901 cgcttttcta atcctacaaa aattgaagtc tatgcagtat aaatatttat aacaattcaa
    12961 acggacaagg tgaaacggga tatttgttta accttgtcct atttcgaatt tattatatgt
    13021 taattacata ttaaaattca tcatcaccaa ttaaatttcc tacatcatta tcctttgtaa
    13081 gtctttgctt caagtaattt tcttttgtag ttctatcatt tttatggcca actgcagctg
    13141 ctatgacatg aggtgctagc cccttataat catataagta ctgtacataa aaatgtctaa
    13201 agaagtgagg ggtaattcgt atattctctg taaaaagtaa cttggtatcc ttaataattt
    13261 tagaaatata ttgtgacaag taattctctc tataagcagt atggttcttt gtttgaaata
    13321 tagtcccacc atttttagtc ccaatgttta caggtaacct tctccggatt cgaaatgcaa
    13381 caatacgatt aaaaatgtcc ttattaatag aaacaatccg ttcattatct ccctttgtat
    13441 caactgttaa atagtaacgt ccacgtatag cgtcatactc aagatcttcc catttggcat
    13501 gagcgacttc tgcaacacgt aatcccgtag tagccaggac cgataataaa gcgtaattga
    13561 tttcattgtc cttatagtaa tgaagcagat gcttcacttc ctcatatgat aactcgcgtt
    13621 ttggtttatg ttgtttatta acggtcgtac ttagaatctc tacatgaaga ggttcctgga
    13681 tatattgaat ttcatacaac catttcaagt aagagcggat tacaccaagt tttctactaa
    13741 tcgtagatgc tttgtacttt tcttttgatt gataggagat tgcctcctgg gataaccact
    13801 tttggtagtt tcggatatgt cgttttctta agttcctcca aacttggcca attacataat
    13861 ctttaacatc ttgctgcaga aattctgtgc tttgtttgat gaaaaaatag aactggctta
    13921 gatcacgtgc atatagagtc ctggatgcat cctttatacg tttttcttgg tcaaaatgtg
    13981 tttgccgatt taagtagtag tacaatattt cttcatctga aaatccctca tatgtatatg
    14041 aatcttctct ttcgttattt tcctttttaa attcagcttc atttatataa tcacgattcc
    14101 ataatgcaat tatgtttgcg aaattttgtt tttgtttctc aatattttct aaagaagttt
    14161 cactatgaat tgtaatcaat tcaaatttca ttgtcattca actccttatt aatttctttt
    14221 gtatctatta ttataactga attacattca aaattattta catatcaaaa ttaaatttta
    14281 taaaaatgaa aatgttatat aaccatagaa aaactcacat tttctatggt tattatctat
    14341 ttattatttt aaattatctt ttatataatt tataattgta taaaagataa tttaattaga
    14401 aattgaattt tcatttcata tatatttaga aataaattaa gtattgattg tgttataatt
    14461 aatttgcact atatatttta gaaatttaac tttatataat aaaattattg atttcagata
    14521 acagaagttt acacatagga ggaaaagata tgtttgaaag acaagaaatg aatatgaata
    14581 cgaatgaagt aaaagcttat ttaggaatta gtagcttcat ttttactact cttataaaac
    14641 aaggacaatt aaatccaatt aatcgagaga cctggcgttt agatggtagc tttttattta
    14701 agcgagaaga catagaaaag ttgaaagaag atcgtgagac agaagggatt accttatatc
    14761 aggcagccaa agattataat gtgagcatgt atcaacttga aaagtggata gaacaagggg
    14821 atttgacttg tactatacag aaacatcgta atcgtgagac taaatttgta catgaggaag
    14881 aaataaatgg attggtacag caattggatc agaccaatac tctatataca ttctcacaaa
    14941 agtataatgt agtattgttc caaaaattta tggaaggtaa taaattagca cgcattatat
    15001 ctattccgaa gcgcggggat attgtactta ttgatgagtt tggaaacaat atgacactgg
    15061 aagatgcaat taaagtgggg tataagcctg catatcttct atccgataaa ccaagaagtc
    15121 atcaccaaaa gtttgtaaaa ttccgttttc ctaaatcaaa tcaattgcga agtaacattt
    15181 ttcacttaat tgacttagta ctacagtatg tatcaccaag aaatattaag gtttctgagg
    15241 aagatggttt ttggtacttt gatgttcgtc aatcgattat tcaattacca atgcaaatgc
    15301 agatagaatg gattgattgt ttaaccccat atataataga aggaaaatta acaagacgtg
    15361 ttaataatag cgtgtattta gatagcagta gtgtcactaa ggcagtaact ataacaagca
    15421 atgaatatca tgcaatcaca aaaattgtaa atgaaacgaa cagttctatt gaagaattta
    15481 ttgcatccgc tattcgcgaa aagattaatg attatcaagc gtcacacaac taatttacaa
    15541 ataaaaaacg gcttaatttt tcttaaaggg ggatatgtta atggaagaaa catggtttga
    15601 tattaaagga tatgaaggca tatatcaagt ttcaaatgtt gggagattta gaagtttaga
    15661 cagaatcggg caaaccggaa aatttctaaa agggaaaata aaagtgcgaa atggtgatcc
    15721 atatggattc aagactatca aattatataa ggatggcaaa ccgaaaaacc ataatgttgc
    15781 tgaaataatt aaaaacactt tcccagaagg aattaaaaag tcctactgga gttaatggtt
    15841 ctggtgcaaa tacttaggaa agatataaag aggcgaaaag tttcctagtg gaatctagtc
    15901 ttaagcaaca attccaaata gttgatggat gaacttcact tgtttttgga cagacttgtc
    15961 cagtaaaata agttgccctt tttttaccat atgcatagct tctattcctg aaagaatgga
    16021 tgtagctgta cgaaaagact tcaatcctaa cattgaacga actctctttt taataaagcg
    16081 atgatcttgc tctacaatgt tattaaggta ttttacctgc cttatttgga tgtctacagg
    16141 cattttttct ctttcttcaa ctctccaatc gctataggat aggccgggtt tttgtctact
    16201 gttatcacac ggggctttga aacatgaaaa gactgcaaag ctttcttgaa aaaacgcttt
    16261 gcagccctat gatctcttgt ttttcttaaa taaaaatcaa ttgtatttcc ttttgaatca
    16321 acagcacgat ataggtacat ccattgacct ttgattttca catacgtctc atcgactcgc
    16381 caagaatcat tggttgattt aagatgacgt cgtactcgct tatctaattc aggagcatat
    16441 tgatgaaccc atcgcatgat agttgtatga gcaagggata acccacgttc ttccatcatt
    16501 tcgactaaat tacgaaaact gaggttgtac cgtaggtacc atctcacggt taataaaata
    16561 atatcaggtt gataatgttt ccacttgaat agattttgct tttccatacc aatcacatcc
    16621 tttttcagag tactagtatc agtatgtcca agtttaggag gttacttaca agcgttttgg
    16681 agtgtttgca ccagaaccat taataatacg cacaaaaaat atccctttat acaaagggat
    16741 acagcggtgc aactttttta taaacggtat aactttcttt aaaacggtac atctttttta
    16801 taaacagtac gactttattt caaaggtaca ttagtattga atatttttcc atcttagccc
    16861 ctcatacccg gaatcatttc cgtaccccgg gttgacaaat agctcaaaaa aagaacccaa
    16921 ttaataggtt ctttttttgt tgctgattat ttttgttcta aaatacgttc aatctcatct
    16981 atgcctaatt tactggcttt agcaatcgtt tcaagtggta caccaagttc atgcatacct
    17041 ttaatcatct gtatttttcc ttgctgaacc ccttgctgaa ccccttcttg aattccttcc
    17101 tttttcccct cattacgagc atgagcaaac tttgcagcct catccattaa agccttttct
    17161 cttgcttcat atgcttgacg gaaagatgaa tcttgactca tacgttccca cttattcatt
    17221 gctttttgta aaatcggatc ttggttcatg gcaatgtcct ccaatgtttg tgtgagatac
    17281 tcatcttcat tcgctggtaa taataataac caacgaacaa acgaatcttc ccacggatta
    17341 actttctctt cgcgccattg ctgtagtaac tttggaatct ctacaatatg aacttctata
    17401 tcgtcactta ataacttttg ttgttgctga ttccaaagga ttcctgttgt atgaaacgct
    17461 tcatattctg gaaacatcac aaagtttaac aagttaatgg taatcgtttt atgaagtgag
    17521 ctataaggca ttcctttttg taattgagag gtgtataacc ttccccaata atacaagctt
    17581 cgtttaatca tatcgtgatt gttattcaac tgtatttcta catttacctt tgttcctgta
    17641 tttaatgtag ccgaaatatc taaaattgat aatttatctt cttcatattc tcgatgtaaa
    17701 tgtggatctt ctaattgtag ggaaacaata ggtgattcta aagaatcttt taaaatggca
    17761 tttaaaaaag caactaaaat atcttcattc ccatttgtgc caaataactg cttaaatgca
    17821 aaatcgatac gtaaatttac taatgaattg gacatggttt tcctcttcct gtttcagact
    17881 atatctttac ctatattgta cataaaacca aagtcaacat gcaaacaatc tctatgattt
    17941 atatagagga tgcatacaga tatacacaat agattatcaa agacgatttg gggtcaccat
    18001 atcattttga gaaaatggta cgctaaggaa tttataaccg caacaaacct tgatttcata
    18061 gggatataag tatttcccct aaaggcatat atttggaaca aatggattga gcgaaaagaa
    18121 ataaagtgat acttaaaata tttatttaaa taaagatgtg aactacaaga attcgacatt
    18181 atacgacaaa acgatataat ttttcagaat attaaaacaa ccatgagatg aggtaactat
    18241 atgaatctat ttcgaaaaaa atctatttca gcattattag cacagtcaga acaaaaagag
    18301 gcatctttaa aaaaagaact cggtgctttt gatcttacta tgctcgggat cggcgttatt
    18361 atcggaactg gaattttcgt tcttaccggt gttgccgcag cagaacacgc aggaccagca
    18421 cttgttttgt cgtttatttt atccggttta gcctgtgtat ttgcagcatt atgttattct
    18481 gaattttcat ctactgtacc ggtatccggt agtgcttaca cttatagcta tgcaacattt
    18541 ggagaattga tcgcttggat tttagggtgg gatttaattt tagaatatgg gttagcttcc
    18601 tcagctgttg catctggttg gtcagggtat ttacaaggac tattaagtgg attcggtatt
    18661 acattaccta ctgctttaac aagcgcatat agtcctgaag cgggaacata tgtagactta
    18721 ccagtaatct gtatcatctt tctaatgacg ttgttattaa caaggggagc aaaaaaatca
    18781 gcatgcttta acgctatcat ggtagctatc aaactctttg tcatcttact atttatcgtt
    18841 gttggagctt tctatgtaaa acctgaaaac tggacaccat ttatgccatt cggcttctct
    18901 ggtgtaacaa ctggagctgc aactgtattc tttacttaca tcggattcga tgctgtatca
    18961 acagctgctg aagaagtcaa aaatcctcag cgaaacatgc caatcggcat cattgcttct
    19021 ttaacgattt gtacgatttt atatattgtt gtttcattga ttttaactgg aattgtacct
    19081 tacgatcagt taggtgtgaa aaaccctgtt gcatttgcac tacaatacat tcaacaagat
    19141 tggattgctg gtttcatttc tttaggagca attactggaa ttacaactgt attactcgtt
    19201 atgttatatg gacaaacacg tttattttac gcaattagcc gcgatggctt actaccaaaa
    19261 gcactttctc gcgtaaataa aaaaacaaaa acacctgtta tcaatagttg gattactgcc
    19321 actatggttg ctttctttgc tggtttcgtt ccttattcgc attcagcgtt gtatcaattg
    19381 gagtagttat tttacgtaaa aaacaaccag aactaccccg cgcttttaaa gtgccctttg
    19441 taccatggat tccggcttta gctgttctat tctgtggata cttagcatta caactcccag
    19501 caacaacatg gatcggcttt gcaatatggc ttgtaattgg acttgttgtc tacttcagtt
    19561 acggttacaa aaatagtacg ctacaaaagg aacaaaaaga aggcgtggca taatgaaaaa
    19621 gctgttgtcc cattaggaca gcagcttttt ccgttctggt acaaaaaata atgtcattgt
    19681 atacaatgac attattcata aataaaggac gtgtacgacg ataaaaaaac agtggatttt
    19741 aaatggaagc attatgaacc ggagattatt ctattagcgg ttagatggta cctgcggtag
    19801 gggcacgaaa acgattatag gtttcaagag tcactatgga attaaaactc ttaagttgat
    19861 ggagccttgc ttatccactt actgttgaaa tatatcgcaa tatatttcct gactattgga
    19921 aattcataat gattagtaaa acacacactc tttaatttgt tttagtaaaa aatatactaa
    19981 atataaatca tgctaaaata aaaaccttaa cttccaatag gcctcaccat acatgcccat
    20041 caacttaaga gaatttgtat cagtaaaaca aaaaaacgcc atccctccta ttctcttttt
    20101 ttaccctctt attatctaaa ttgtactaaa aaagtattgt tctaggatac aatagagtca
    20161 aaagatgtga tattagaatg gctcgaacca ttgatatatc aatattaata gagggggtaa
    20221 ttatatgatt cgtgaagctg aaccaaaaga cagtaatgta attgaaaatc tatataaaaa
    20281 attagcacca catagtaaaa acattaaggt tttaccagaa agaattgagc agataaggaa
    20341 tgattctaat aatttcttat ttgtatatga ggaagattgt aaagttaaag gaagtatatt
    20401 tatgactttt tgtcttgatc ctggatatca atttagacca tataccgttc tagagtatgt
    20461 gattgtaaat gaagattttc gaggtaatgg gataggtgaa aagttactaa aacatgtaga
    20521 acggctatca attgcaaggg gatccacaag aattatctta ttaagtagta caactagaat
    20581 agaagcacat aaattctttt ctaaaaatgg ttataatggc actataagta agggattcaa
    20641 gaagtatata ccaattaatt aagttttata tataagagcc attcttagct ataggaaggc
    20701 tttcttaatt atctttaaat taactaacac agtttaaaag aagtcaacga tgcataaagt
    20761 tttcgttatg gggataattc aaaaccttag gttgatagtg atgtgaagtc ccccctaaac
    20821 gaaaattttt acctatcgac aattcagctc attttttcag tttggggtaa caacgaattc
    20881 tttgtacact agcatgattt tttgttcctc ctattgattt atactttata tttcttacta
    20941 tttcagcgaa aatgaaaact agacctatac catccattta aaacaggagg aaacacaaat
    21001 gaaatgttat caattgcact tggaattagt ggaatgtcct ttccccattt ggagaagagt
    21061 tagtttaccg acagatttat cctttgatga tttacatgac gtgattcaat gcttatttca
    21121 gtggcaacac caacatttat ttgaatttac tgtggggaaa tatgtaattt catctcctcc
    21181 tgatccgagc atttcctttc atacattggc aatgactacg tcgtccccga tgctacatgc
    21241 tgataaaact atgctacacc aacatatcgg aaaaacggat caggcttttc aatatgtata
    21301 tgattttgga gatcattggc tgttacagat tcatgttgaa aagatatttg atcaaccttc
    21361 tgatgaaata aaatgtatag gaggagaaaa tgcggcgcca ttagaggata ttgggggcat
    21421 tccagggtat attgaatttt tagaagcgat aaaagattct tcacacccac aacataaaat
    21481 ctacgcagaa tgggatttat taaattttga tccttctttc tttgacatac acgaaattaa
    21541 taaaggatta acttattgtg attaagtact aaatgaatgc tagtttattt atgggatatc
    21601 gccacatcgc tatcaaccta acaaaacaaa ataccccata aaatgaaaaa atatgctatt
    21661 ctttcctatg attctacaga aaggataacg tattttttgc tttatgggta gtgctatccc
    21721 ttatatgact tcttgtgatt tcggtgaaag tcgtgatggt acttcataac cttagcttat
    21781 gcaaagtcaa ttttaggcga gattgtttct tttttctaaa gagcaagtgt aggtgattga
    21841 aagatttgca tacgaaataa accctaacgg gtttcacttt tttgaattaa gcggcttgat
    21901 tatcagacat agtacaattg taaacgacac ctaatatatc aaagaccgtt tttttctcat
    21961 atcgatgaga tttccgcccg ttttgctgta ggagattgaa caggcgaagt aacacctttg
    22021 atagctcttg ggtgtttttt tgtatagttt ggaatagaag aagaaaatag tctttaatca
    22081 tatatatggc tttatactca ctaagctctc gttttttctt catgaggagc aattggcgca
    22141 tttgaaacat gatagaagaa cagagtagaa tggcaatcaa ttgaccatat aaatggcact
    22201 tcaatcgttc tggttttatc tttttacaat gatgaatttg aaagaatgac ttccacgttt
    22261 taaataaaat ttcgatttgc caacgcaaag aataccagtc atgtacctgt cccatcggga
    22321 caatatctgt agaggtgttt gtcatatata cattgatacc actgagtcgt ttactacgag
    22381 gagaatactt cattcctttc tttttttctc ttacagcttg atcttgtaat cgtttttgtt
    22441 gctgttgctt tgttaatcga tgaacaatta cacgagctgg cactttatca atcatac
//
