LOCUS       NZ_CP036117            23535 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Bacillus mycoides strain JAS481 chromosome, complete genome.
ACCESSION   NZ_CP036117
VERSION     NZ_CP036117.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus cereus group.
REFERENCE   1  (bases 1 to 5296574)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5296574)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.86x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018741645.1-RS_2024_12_12
            Annotation Date                   :: 12/12/2024 04:46:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,189
            CDSs (total)                      :: 6,036
            Genes (coding)                    :: 5,734
            CDSs (with protein)               :: 5,734
            Genes (RNA)                       :: 153
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 302
            CDSs (without protein)            :: 302
            Pseudo Genes (ambiguous residues) :: 0 of 302
            Pseudo Genes (frameshifted)       :: 122 of 302
            Pseudo Genes (incomplete)         :: 192 of 302
            Pseudo Genes (internal stop)      :: 81 of 302
            Pseudo Genes (multiple problems)  :: 78 of 302
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:51:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1270426
            Orig. end                         :: 1293961
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036117.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13535](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            428..1204
                     /gene="trpA"
                     /locus_tag="EXW43_RS06965"
                     /old_locus_tag="EXW43_07165"
     CDS             428..1204
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016133917.1"
                     /locus_tag="EXW43_RS06965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07165"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_215576129.1"
                     /transl_table=11
                     /translation="MGVEKIIAAFENGKKAFIPYVMGGDGGLEKLKERIRFLDEAGASI
                     VEIGIPFSDPVADGPTIQRAGKRALDSGVTLKGIFQALIEVRQEVQIPFVLMTYLNPVL
                     AFGKERFIDSCLEAGVDGIIVPDLPYEEQDIIAPLLRVANIALIPLVTVTSPIERIEKI
                     TSGSQGFVYAVTVAGVTGVRQNFKDEIRSYLEKVKAHVYLPVVAGFGISTREQIEEMIT
                     ICDGVVVGSKVIELLENEKREEICELIHAVKETEEA"
     misc_feature    complement(1231..1249)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            1279..1629
                     /locus_tag="EXW43_RS06970"
                     /old_locus_tag="EXW43_07170"
     CDS             1279..1629
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086916.1"
                     /locus_tag="EXW43_RS06970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07170"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_016126699.1"
                     /transl_table=11
                     /translation="MLRRKLLYLFLTVPLYAWLISMTKIELMALFLGYVFIFSQLNRIQ
                     EQSILEVCIFSISIELFSIVSIVLLSELFQWIHSFELIKLGNIVLQVICAYIVFVVLEK
                     MIGQQTVFQDKR"
     gene            1757..3256
                     /locus_tag="EXW43_RS06975"
                     /old_locus_tag="EXW43_07175"
     CDS             1757..3256
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168880.1"
                     /locus_tag="EXW43_RS06975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07175"
                     /product="L-lactate permease"
                     /protein_id="WP_003188030.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRASLISYAVSVGIVLLSPTF
                     QLGISETVHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPIFAYFIFLSLYVVGGWQAVIEKCKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSEQNFITEHAATAEREVSIIKIISP
                     YIFLTVCILLSRLVPVLHDFLRSYAVLDLKSYSYKLELLYSPGFWLAMTCLFTIIFFRI
                     PSNIIKQSLSQTIKQWIPFAITTTMFIAISELMGASGMHSLLAKTAGETFGTFFVFVAP
                     FIGGIGGFLTGSNAGSNAMFIKLQMQTAQNVAIPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVVVEVIVWYMLRK"
     gene            3348..4031
                     /locus_tag="EXW43_RS06980"
                     /old_locus_tag="EXW43_07180"
     CDS             3348..4031
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128607.1"
                     /locus_tag="EXW43_RS06980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07180"
                     /product="DUF2278 family protein"
                     /protein_id="WP_033730649.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVVQSKIGKGKTPHYQVHLQGEAGVNYRIAINVK
                     SQSYPSEVLYFASNNIRSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQMIPL
                     PAEKSGSDNDLNEKIEHYIKRAIDEKAIIYAFGERWGPEEKVPDSYFHFTPGNGIHDIH
                     MNQGNVEKWQGDDGKWQDGGILIHFEKKEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKRNN"
     gene            complement(4046..4879)
                     /locus_tag="EXW43_RS06985"
                     /old_locus_tag="EXW43_07185"
     CDS             complement(4046..4879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="EXW43_RS06985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07185"
                     /product="hypothetical protein"
                     /protein_id="WP_078422197.1"
                     /transl_table=11
                     /translation="MEFVNSIFQTLLTSVIQLFSLIGVIIVIGFILGYLESLTRTYWSR
                     AFGRKGFLLTAWIGVPVHELGHAIMCLLFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     IYQRIGNFFIGIGPIISGITALILLMRYFVPDSYSLFNTNLEKTVTSTSISLDMIQNML
                     LSTFVLLKSLFTFSNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNQLIGKMMKYNMYFIAFSSVALLFSCISTLVSFVFYKIRRGRSL"
     gene            5080..5862
                     /locus_tag="EXW43_RS06990"
                     /old_locus_tag="EXW43_07190"
     CDS             5080..5862
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158836.1"
                     /locus_tag="EXW43_RS06990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07190"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_002126012.1"
                     /transl_table=11
                     /translation="MKCPACNTENAAEARFCGNCGHSLTEEVVASGGQEEGQLSRPARV
                     KETRPNETVEQVKQFASGYFQFFKNAFKSPSAIMESGNIEVRNGIVSLVLICFLGACIF
                     YRMMSAAATVTRTLVPDIATPTFFGESVMVFFFLLILTLFVGFIIFVSGKMMKSSFSFL
                     ESFGIWGTIATPAIAILVLSFLFSFLLIFFLPILLGLATTYMGISIIVAILKLDNGGVD
                     PVYTLIIANVLIGIATFIVFWSYIKTIIQTFIGGLTGF"
     gene            5882..7120
                     /locus_tag="EXW43_RS06995"
                     /old_locus_tag="EXW43_07195"
     CDS             5882..7120
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="EXW43_RS06995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07195"
                     /product="TcaA 3rd/4th domain-containing protein"
                     /protein_id="WP_078178303.1"
                     /transl_table=11
                     /translation="MNVCTKCGTHFEDSVQFCQNCGTKRRDPVVKKQKMSKGTIIGITL
                     LTFFIIVLGGLYAYGSSYYSQSSQVERIITVLQERDGEKLAEITTADDPAVIVTRESVT
                     ALFSYIKENPSYVNELNEYLRQGEKQGDGIERADFSLTKDGKYFFLFDRYKLKAKTYYT
                     TLLSNEKGTSLKMNGKEIDKTNDKKFEKQYGPFLPGTQVFQAEYKNDYVKLSREEKVVL
                     IKQSQNNVTVDLTLQGQYITVQTNASGATLYVNQKPVTALTGEEITWGPIATDGSAAIY
                     LERNGENGRETTKVETVTALSAYNLPFQKKSVEKTVVYNVTPPPTTHYVYNGFIFPDSD
                     IRKLTSTDLTYLSKEQLKIARNEIYARHGHMFQTKDMQAYFSKQSWYRENPYFTGKLTD
                     IETYNVELIKSRE"
     gene            complement(7164..7586)
                     /locus_tag="EXW43_RS07000"
                     /old_locus_tag="EXW43_07200"
     CDS             complement(7164..7586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332411.1"
                     /locus_tag="EXW43_RS07000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07200"
                     /product="hypothetical protein"
                     /protein_id="WP_002188801.1"
                     /transl_table=11
                     /translation="MCAGLLAQTPEEPQEPKAAMPLDQEFSINVTLYSARAWLSNDETF
                     AQTIWKGSRFSSASHAGKSILPIGTVKIVNLSDDTITVTASSEKDDTLKIVVPPRSEGV
                     LTSSALSDVQASTSGGASKVTFLFHIFFSRDPGPAK"
     gene            7786..9120
                     /locus_tag="EXW43_RS07005"
                     /old_locus_tag="EXW43_07205"
     CDS             7786..9120
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="EXW43_RS07005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07205"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_215576130.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.4e-62, bitscore:
                     207.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGVIASTEKLIARDVKTFRDKYGIDAKVRHEVTKVDTEKKMVYAEHTETKDVFEFP
                     YDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEAVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGKER
                     VEQLETDKGTYKTDLVLVSVGVQSNTDFLEGTNIRKNHKGAIEVNAYMQTNVKDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMVDKRRAFKGTLGTSIIKFMNLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPSALPLHLKLLYHADTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            9280..9690
                     /locus_tag="EXW43_RS07010"
                     /old_locus_tag="EXW43_07210"
     CDS             9280..9690
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="EXW43_RS07010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07210"
                     /product="DUF3908 family protein"
                     /protein_id="WP_002126019.1"
                     /transl_table=11
                     /translation="MAINMNTIEEWIAESNARNEEDLGNVVEEMKEVCVGLDNATLIYT
                     KNIFCFGKKVEVFFFFQDHVVIGEEKEEYIEIEKLKYDDITNSNLKTNDKNTTLELKFS
                     NGKAINLDSLNDNYGTKNWLFARQIKSIFKVI"
     gene            complement(9723..>9926)
                     /locus_tag="EXW43_RS07015"
                     /old_locus_tag="EXW43_07215"
                     /pseudo=""
     CDS             complement(9723..>9926)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158829.1"
                     /locus_tag="EXW43_RS07015"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07215"
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="IKNDMKEVFRVLKPNGSFLLVAETFKIQYHMDKFKTTEELVNLFY
                     ETGFTSVKCYEERGCLFLIGNK"
     gene            complement(10001..11563)
                     /locus_tag="EXW43_RS07020"
                     /old_locus_tag="EXW43_07220"
     CDS             complement(10001..11563)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135039.1"
                     /locus_tag="EXW43_RS07020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07220"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_002126024.1"
                     /sec_met_domain="PF00881 (E-value: 8.3e-10, bitscore: 37.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPDTFLHHLHFSINEIMSSDKEIDWEDAPLPYKLYRNLPVIPLS
                     LEIPLTLRNSSTKPNLEEIGHYLWYSFGLTQLCQPTTNLENNKTTTLFRRFIPSGGALY
                     PNELYMYLKIDHYPDGIYHYDAAHHRLILLREGNFDSYLTEALGNRCNIHSCFGAAFVS
                     TMFWKNFFKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRAMNHLLGLSE
                     GEESVYAVIPLSTEPNTDWFHDDHHENKTITSHDLLQQIPPLTHEHFVRSKYVDEYPMI
                     KKINAASMIESTEHFQTFTREERQQYSAHAMQLPKVERLSYDFLQLCKKRYSPDSDFIL
                     TKWDAAELATLLQAASLSFPYYNDLDGKYLNENARVSLYGCFYNVKDIENGAYAYNSRT
                     HSIQPIRYGDLRYSLQSSMTMDNVNLFQVPLCLHVIGNKDYYKNKLGYRGYRIHQMEAG
                     MLVHKLVLAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQIPVGAYRARNWLKGS
                     LHN"
     gene            complement(11586..13535)
                     /locus_tag="EXW43_RS07025"
                     /old_locus_tag="EXW43_07225"
     CDS             complement(11586..13535)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="EXW43_RS07025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07225"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_199626847.1"
                     /sec_met_domain="YcaO (E-value: 1.4e-83, bitscore: 279.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.2e-138, bitscore:
                     460.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLTDYVHEQLCKQYSLIRQHTITEALPENIHLAL
                     VLHDGSPSSVHRDAELIFRSNNIPWLRAFTSFGEGIIGPYVKPLTTGCSHCADGRRFIA
                     GFDQKEMWELQRKYALKAENVTRRDVRATQNGMLQMCQLIHAETEKILAHGYSSLENEL
                     ILLDLQTLQCTRNSFLPDPLCPVCSNLPDDTADAAQISLQPSLKTSTETYRCRSIHELN
                     TFLTRDYLDYRTGILNGKMQHSLLPFADVIINMPLLFGNEGVAGRTHSFSLSEATAILE
                     GLERYCGMSPRGKKTNVHGSFRELEDIALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLLQSRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMLERLRTITGYELYVFNATMEHGIPSIWVIAK
                     NTRQDGMNLVCAGGAHMEPIRAVKNAIHEIAGMLLITDEELEQKREKYENCLQDPYLVS
                     QMEDHSMLYGLKEAEERLHFLLRDDAPVQTFQEMKVLQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVDQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYWAEP
                     LTNESLNPHPHPFP"
     gene            complement(13532..15451)
                     /locus_tag="EXW43_RS07030"
                     /old_locus_tag="EXW43_07230"
     CDS             complement(13532..15451)
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="EXW43_RS07030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07230"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_002186383.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1159.9,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.3e-55, bitscore: 181.4, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.9e-11,
                     bitscore: 41.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFERYRAANVLIIGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     AETNYDRIHELSERAYANDDNVLIQEIDITIDRPLHEVFEPFDWILYVSQNGDIESLRA
                     IHTICREFKKNFIPAMCLSRIGLAGPVVTADREECWESAWHRLHETTLQSENPPEPFSP
                     IASAMLANVIVFELFKLVAEDSHRQHNPQFFLLNLETLEGKWHPFIKHLLATDEIFTID
                     TVQNLQENLAQRSGQYTSTELFRFFDTLTSKEAGIFHMWDEQDLHQLPLSQCNIQVANP
                     LSDGPTSPLPTITCGGLTHNEARREAGLTGVETYVAEMIHRLIPEHTDIGIGAGETMTE
                     GVYRALQKHLNNKLYERQSHMLEEITELYLTEIHDKHCRFYYDALSTIHEIPKVGMSEE
                     LLGFPVVWIGINDRWYGAANINITLALRNALQQALLHIQNEEIPYKANMLPESSIVLYS
                     TDPVRVAIQEEEEIPGVQSLQVALQNLTENNLYPFVFDLAIESFLRDNLDGVYGVLIAK
                     EDDQ"
     aSDomain        complement(15152..15451)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW43_RS07030_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.40E-57"
                     /identifier="RREFam011.1"
                     /label="EXW43_RS07030"
                     /locus_tag="EXW43_RS07030"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.4"
                     /tool="antismash"
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNS"
     aSDomain        complement(15185..15424)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW43_RS07030_Thiopeptide_F_RRE.1"
                     /evalue="1.50E-13"
                     /identifier="RREFam004.1"
                     /label="EXW43_RS07030"
                     /locus_tag="EXW43_RS07030"
                     /protein_end="89"
                     /protein_start="9"
                     /score="41.5"
                     /tool="antismash"
                     /translation="LKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDWIEKLMPMFN
                     GNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRD"
     gene            complement(15577..16833)
                     /gene="odhB"
                     /locus_tag="EXW43_RS07035"
                     /old_locus_tag="EXW43_07235"
     CDS             complement(15577..16833)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="EXW43_RS07035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07235"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_002168867.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESISEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAAVEVSTPAPANEQPKQETTEAPKA
                     AAPSAEQNKALQGLPNTNRPIASPAARKMARELGIDLNEVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKQSPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDM
                     SAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYDI
                     GIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGLKARDNKLSLKELQGGTFTITNGGV
                     FGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAVS
                     FLVAVKDMLEDPKSLLLEG"
     gene            complement(16963..19830)
                     /gene="odhA"
                     /locus_tag="EXW43_RS07040"
                     /old_locus_tag="EXW43_07240"
     CDS             complement(16963..19830)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="EXW43_RS07040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07240"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_002126030.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLIEKTMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVSEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYNHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTTKSFVILVHGDAAFPGQGVVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQSAGVLNADEVETITQFIQEELKAEYA
                     QVPPADTSAATIHVKVPEVVAKGIQPIDTGVSIESLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVIMTPKSLLRHPLTLSTGSELSEGRFQPALEQGNLGA
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHMVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVFSN"
     misc_feature    20478..20498
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 30.06"
                     /tool="antismash"
     misc_feature    20530..20544
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            20657..20866
                     /locus_tag="EXW43_RS07045"
                     /old_locus_tag="EXW43_07245"
     CDS             20657..20866
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="EXW43_RS07045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07245"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428506.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGE"
     gene            20869..21246
                     /locus_tag="EXW43_RS07050"
                     /old_locus_tag="EXW43_07250"
     CDS             20869..21246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="EXW43_RS07050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07250"
                     /product="permease"
                     /protein_id="WP_078202976.1"
                     /transl_table=11
                     /translation="MNYSQKYFVMMGIIFLFMSGFMILTGIMTHSAPPAPTYTLLAMMI
                     MCFCLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKIMTLSAVELLN
                     ILMALTMSTVFISFVVLSKRY"
     gene            21275..21457
                     /locus_tag="EXW43_RS07055"
                     /old_locus_tag="EXW43_07255"
     CDS             21275..21457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="EXW43_RS07055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07255"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_002086895.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLINQSL"
     gene            21592..21954
                     /locus_tag="EXW43_RS30650"
                     /old_locus_tag="EXW43_07260"
                     /pseudo=""
     CDS             21592..21954
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034130.1"
                     /locus_tag="EXW43_RS30650"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07260"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKKAIFFLLTCLLLIASITYIICNK"
     gene            21971..22240
                     /locus_tag="EXW43_RS07065"
                     /old_locus_tag="EXW43_07265"
     CDS             21971..22240
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126037.1"
                     /locus_tag="EXW43_RS07065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07265"
                     /product="hypothetical protein"
                     /protein_id="WP_002126037.1"
                     /transl_table=11
                     /translation="MQRVTSYPWSLRKIFVFFLCFILPPIGAIYILMNREALQKRDYIL
                     YLLFAAINISLWLSLMIFDRSMWMVAGHDVLGVIVIIFSNMNKS"
     gene            22321..22866
                     /locus_tag="EXW43_RS07070"
                     /old_locus_tag="EXW43_07270"
     CDS             22321..22866
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="EXW43_RS07070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW43_07270"
                     /product="hypothetical protein"
                     /protein_id="WP_002126038.1"
                     /transl_table=11
                     /translation="MRWKAGTFEKIETNDSSVEKIINTFKEQNLNGGAIISCFKVHNEN
                     FFKEIPHSKDGYEHFFRRIFNSLDIIHNLEELKIHTSEKYKFHFKEHLVVMLDGSIAAQ
                     ILWGGAYEGFKERPVIAKQLAVNVCQYMFQDRYEDIKVFESYRPWTDWFYDVAWDATWM
                     VLDSKEHKMWLVCATDTD"
     misc_feature    complement(22881..22897)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
ORIGIN
        1 cggtgttgaa gcagctggaa aaggtgttca cacagaaaag cacgcagcca ctttaacgaa
       61 aggaagtgtc ggtgttttac acggatcgat gatgtacctt ctgcaaaatg aagaagggca
      121 aattcaagaa gcgcactcta tttcggcagg gctggattac ccaggtgttg ggccagaaca
      181 tagcttgcta aaagatattg gccgcgtttc ttatcattcc attacagatg aagaagcgtt
      241 agaagcattt caattattaa cgaaaaaaga agggattatc ccggcattag aaagttcaca
      301 tgctgttgca tacgctttaa aactagcgcc gcaaatgaag aaagacgaag gacttgtcat
      361 ttgtttatcc ggccgcggtg ataaagatgt agagagtata aaacgttata tggaagaggt
      421 gtaaaaaatg ggagtagaaa aaattatagc agcgtttgaa aatggcaaga aagcatttat
      481 tccgtatgta atgggcggag atggtggact tgaaaagtta aaagaaagaa ttcgttttct
      541 tgatgaagca ggagcaagca tcgttgaaat cggtattccg ttctcagatc cagtcgcaga
      601 cggtccaact attcaaaggg caggaaaaag agcattagat agcggtgtaa cattgaaagg
      661 tatttttcaa gcattaatag aggtgaggca agaagttcaa attccatttg tacttatgac
      721 atatttaaat ccagtactcg cattcggaaa ggaacgtttc attgacagct gtcttgaagc
      781 aggggtggac ggtattatcg ttccggactt accgtatgaa gaacaagaca ttattgcacc
      841 gctccttcgc gtggcgaata tcgctttaat tccactcgtt accgtaacga gccctattga
      901 acgaattgaa aaaattacga gtggatcaca aggattcgtc tacgccgtta cagtagcggg
      961 cgtaacggga gtacgtcaaa actttaaaga tgagattcgt agttacttag aaaaagtaaa
     1021 agcacacgtc tacttaccag tagtcgcagg attcggtatt tcaacacgag agcaaattga
     1081 agaaatgatt acaatatgtg acggcgttgt cgttggaagt aaagtcattg agctgttaga
     1141 aaatgaaaag cgagaagaaa tttgtgagtt aatacatgca gtaaaagaaa cagaagaggc
     1201 ttaagtctct tctgtttctt ttgtgtaata aatgttaaaa tatacagaaa atacttataa
     1261 cttagagggt gagaaggcat gctaagacgt aaactattat atcttttttt aactgtacca
     1321 ttatacgctt ggctcattag catgacgaaa atagagttga tggctctgtt tttaggatat
     1381 gtattcatct tttcccaatt aaatcgaata caagagcaat ctattttaga agtatgtata
     1441 ttttcgatta gtatagaact atttagtatc gtttcgattg tattattaag tgaattattc
     1501 caatggatcc attcatttga attaataaaa cttgggaata ttgtattgca agtaatatgt
     1561 gcttatattg tgtttgttgt actagaaaaa atgattggac agcagacggt ttttcaggat
     1621 aaaagataaa atattagtta ttcaaaaaag gagccaagcg gctccttttt aaaatctgtt
     1681 ataaaaataa ttgaaaatca taacatctgt tatataatag ttaaaaattg caatttttac
     1741 gaaaagagat gatagcatgg ccatattgtt ggcacttatc ccaattatga tgatttttat
     1801 ttgtttattt ttgtttaaac aaacgtcatt aagggcttca ttaatttctt atgccgtttc
     1861 tgtcggaatc gttttacttt cgccaacgtt ccaattaggg ataagtgaaa ctgtgcacgc
     1921 aacgattaaa ggttggttaa tttgttttat tgtcggatac gttttatttt tcggtatttt
     1981 tttatttcac ctcatgaaca aaatggggta catcgatcaa gtagcgcgtt ttctagaaga
     2041 agttacgcac gatcgcttac tacaaatgct tcttatgtgc tttggcattt gtccacttat
     2101 tgaatcagta agtggattcg gaattggttt tatggtcgca gcacctattt ttctttcgct
     2161 cggttataaa ccgtttcaag ctgtgctact atcgtttatc ggtttacttg caagttcatg
     2221 gggcgcgatg gcaacgggta cgattatcgg ttctcagctt attaacatgc cgctcacaac
     2281 tcttggtaca aatacagcat tattaagcat cccgattttc gcatatttta tcttcctttc
     2341 tttatacgtt gtcggtggct ggcaggcagt tatagaaaag tgtaaggaag gagtaggatt
     2401 ctttctatta ttttctctcg gaatctatct ttctaacgca tacgtaagtg ttgaacttgc
     2461 agggatatta agttctatcg ttaccattac atttggcttt ctaatcatta aattaaaagg
     2521 caaaagtgag caaaacttta taacagaaca tgcggcgact gcagagagag aagtatctat
     2581 tataaaaatt attagccctt atatattctt aacagtttgt attttacttt cccgcctcgt
     2641 tccagtatta catgattttc ttaggtcata tgcagttctc gatttaaaat catattctta
     2701 caaactagag ctactatatt caccaggatt ttggctcgct atgacttgtt tatttacaat
     2761 tattttcttc cgcattccat caaatattat taaacaatca ctctcacaaa cgataaaaca
     2821 atggattcct ttcgctatta caacgacaat gtttatcgca atttcagaac taatgggtgc
     2881 atctggtatg cattcattac tcgcaaaaac agctggtgaa acatttggga cgtttttcgt
     2941 tttcgttgct cctttcatag gcggaattgg cggcttttta acaggtagta acgcaggatc
     3001 aaatgcgatg tttataaagc tacaaatgca aacagcgcaa aacgtagcga tcccgtggca
     3061 atatgtcaca acactccaaa acaccgcatc atcagtagcc acaatcgctt gtccatcacg
     3121 gattacacta ggcgcgtatt tatgtaatat cccttatcgt gaaaatgaac tattaaagaa
     3181 gacgacgtta atgatttttg gtgcggtgtt gcttgtagtg gtggaggtta ttgtttggta
     3241 tatgttgaga aaataagaaa tcctcctggg aaaggaggat tttcttttta tatggataat
     3301 gcctaaagta tgaaaagctt ctactaaatg aataggagat gaaagagatg cccttaaaaa
     3361 actacggtgt attaaaaggt acagttgtac aatctaagat tggaaaaggg aaaacacctc
     3421 attatcaagt tcatttacaa ggcgaagcag gagttaatta tcgcattgca attaacgtga
     3481 aatcgcaaag ctatccgtcg gaagttttat attttgcgag taacaatatt cgatcagagg
     3541 cgattcatat tttaccgaca ttaccgttcg gttttacgga agtgaaaaac aatgagccga
     3601 aagtagcttt agattatgta agaggtaatt tatttgattc aaagcaaatg attcctttac
     3661 ctgctgaaaa atcgggatct gataatgatt taaatgagaa aatagaacat tatataaaaa
     3721 gagcaataga tgagaaagca attatttatg cgtttggtga aaggtgggga ccagaagaaa
     3781 aggttccgga ttcgtatttc cactttacac ctggaaacgg tatacacgat attcatatga
     3841 atcaagggaa tgtagagaaa tggcaaggtg atgatggcaa atggcaagac ggtgggatat
     3901 tgattcactt tgagaagaag gaagagtgga ttggtatttt tcttgccttt cagtcacagt
     3961 catggtgtac cgatgaagaa gggcacgctc gtgttccggt tgagcattgt gattataaga
     4021 gaaataattg atgagaagag ggcgttcaca atgaacgccc tcttcttatt ttataaaaca
     4081 caaaactcac aagtgtagaa atacaagaga aaagaagcgc cacactagaa aacgcgatga
     4141 aatacatatt atacttcatc attttaccga ttagttggtt actatcgtac tgaaacagtc
     4201 ccgctattat attgaataaa aataatacga taaacatgac gataacaccg tctattgatc
     4261 ctttaatgtc tggtttactt aaagcgatat gtgcggaaat gcaaatagcg ataaataaaa
     4321 ataaccaaaa tgaaggattc aataaattgc taaatgtaaa taagcttttc aataatacaa
     4381 acgtcgatag tagcatgttt tggatcatgt ctaagctaat agaagtcgat gtaacagttt
     4441 tttccagatt cgtattaaat aaagaatatg aatctggtac gaaatagcgc attaaaagta
     4501 ttaaggcagt aatcccagaa ataataggac cgatgccgat aaagaaatta ccgattcgtt
     4561 ggtatatact tttttgattg tattgatgtt gtacgtaacc taaagctccc tgacttgtat
     4621 ctgttgggaa aaactgcgtt gctacaattt tatgacgaaa taatagacac ataattgcat
     4681 gtccaagctc atgaacggga acaccaatcc acgcggttaa aagaaaacct ttcctaccaa
     4741 aagctcttga ccaatacgtt cgtgtgagag attctaaata acctaatata aatccaatta
     4801 caatgatgac accaattaaa gaaaataatt ggatcacact tgtaaggagt gtttgaaaaa
     4861 tcgagtttac aaattccact gtcttcatcc aatctgttta aagtttcact ttatttgctc
     4921 tgtttcataa taacattatt tttctatatt actagcacac atagtttcgt ttaaaagaag
     4981 gatttcatat tctttttctt gtagtcatgt tttatgtaca aagtcatata ttgaatttgt
     5041 aacaccctat aaggtatatg cttaaggagg gatgagagaa tgaaatgtcc ggcatgtaat
     5101 actgaaaatg cagcggaagc aaggttttgc ggcaattgtg gacattcgtt aacggaagaa
     5161 gtggtagcga gtggtgggca ggaagaaggg cagctatcgc gcccggcacg agtaaaggaa
     5221 actcgtccga atgaaacggt agagcaagtg aaacaatttg caagtggcta ttttcagttc
     5281 tttaaaaatg cttttaaatc accatcggcc attatggaaa gtggaaatat tgaggtgcga
     5341 aatggaattg taagtcttgt gcttatttgc tttttaggag catgtatttt ttatagaatg
     5401 atgagcgcag cggcgactgt tacgaggaca ttagtgccag atatagctac tcctactttc
     5461 tttggagaat ctgtaatggt ctttttcttt ttattaattt taactttatt tgtcggattt
     5521 attatttttg taagtggtaa gatgatgaaa tcatcttttt cttttcttga atcattcggt
     5581 atatggggga cgatagcgac gccagctatt gctatactag ttctttcttt tctatttagt
     5641 ttcctattga tctttttttt accaatctta ttagggctgg ctacaacgta tatgggaatt
     5701 agtataattg tagctatatt aaaactagac aacggcggag tagatcctgt ttacacactt
     5761 attatcgcaa atgttttaat cggaattgca acgtttatcg tgttttggtc ttacattaaa
     5821 acgataatcc aaacctttat cgggggatta acaggcttct aacgaaaagg tggttgaatg
     5881 gatgaatgta tgcacaaagt gcgggactca ttttgaagac agtgtgcaat tttgtcaaaa
     5941 ctgcgggacg aagaggcggg atcctgtagt aaagaagcag aaaatgagca aagggacaat
     6001 aattggaatt acacttttaa cattttttat tatagtattg ggcggattat atgcgtatgg
     6061 atcttcatat tactcacaat catcgcaagt agagagaatt attactgttt tacaagagag
     6121 ggacggggag aaattagctg agatcaccac ggcagatgat ccagccgtta ttgtcacaag
     6181 agagagtgta acggctctat tttcatatat aaaagaaaat ccatcttacg tgaatgaatt
     6241 gaacgaatat ttgaggcaag gtgaaaaaca aggggatgga atagaaagag cagatttttc
     6301 tttaacgaaa gacgggaagt atttcttttt atttgatcgg tataaattga aagcgaagac
     6361 gtattatacg acgctgcttt caaatgaaaa aggtacatct ttaaaaatga acggaaaaga
     6421 aattgataag acaaatgaca aaaagtttga gaagcaatat ggaccgtttc ttccaggaac
     6481 tcaagtgttt caagcggaat ataaaaatga ctatgtaaaa ctatcacgag aggaaaaggt
     6541 tgtacttata aaacaaagtc aaaataatgt aacggtagat ttaacgttgc aagggcaata
     6601 tattacagtt caaacgaatg cgtctggtgc aacattgtac gtgaatcaaa agccagttac
     6661 tgcgttgact ggagaagaaa ttacgtgggg accgatagcg actgatggaa gtgcggcgat
     6721 ttatttagaa cgaaatggag aaaacggaag ggaaacgaca aaggtagaaa cggtaacggc
     6781 actttcggct tataatcttc catttcaaaa gaaaagtgta gaaaaaacag ttgtttacaa
     6841 tgttactcca ccgcctacga ctcattatgt atataatggt ttcatcttcc ctgatagtga
     6901 tattcgaaaa ttaacgagta cggacttaac atatttatcg aaagaacaat tgaaaatagc
     6961 aagaaacgaa atatacgcaa gacatggaca tatgtttcaa acgaaagata tgcaagcgta
     7021 tttttcaaaa cagtcttggt atagagaaaa tccgtatttt acaggaaagc taacagatat
     7081 tgaaacttat aatgttgaat tgatcaaatc aagagaataa acgcgtgaaa aaggtacagt
     7141 gcatagctgt accttttcta tggttattta gctggaccag gatcccttga gaaaaagata
     7201 tgaaagagga atgtgacttt gcttgctcct cctgatgtac ttgcttgcac atcagataat
     7261 gcactagatg ttaaaacacc ttcagaacga gggggtacga ctattttgag agtatcatct
     7321 ttttctgatg aggcagtaac tgttattgta tcatcagata agtttacaat tttaacagta
     7381 ccgattggta agatggactt gccagcgtgt gatgctgaag agaagcgaga gcctttccaa
     7441 atcgtttgtg cgaaagtctc atcattagat aaccaagcac gagcgctgta taatgttacg
     7501 ttaatagaaa attcttgatc aagtggcatg gcggctttcg gttcttgcgg ttcctctgga
     7561 gtttgagcga gaaggccggc gcacatgtat gtttcaccta ctttcaatag ttactgttat
     7621 agcatattaa acatcttgtt tataagacac gacggatacc tattcatgca taggtttgtg
     7681 caccaaattt gtagatagaa ttctatttct ttacaatgga agtaggtgtt atttctataa
     7741 aatatggaaa tcgtaaagag tatgtaaaaa agaaggagtg gtaaagtgaa ctatgtcatt
     7801 attggcggag atgcagcagg tatgagtgca gcaatgcaaa ttgttagaaa cgatgaaact
     7861 gcaaatgttg taacgttaga aaaaggtgaa atctattcat acgctcagtg cggattaccg
     7921 tatgtgatta gtggtgttat tgcttctact gaaaagttaa ttgcacgcga tgtaaagacg
     7981 tttcgtgata aatatggaat tgatgcgaaa gtacgtcatg aagtaacgaa agtagatacg
     8041 gaaaagaaaa tggtgtacgc agagcatacg gagacgaaag atgtttttga atttccgtat
     8101 gaccgtttat taattgcgac tggagtgcgt cctgttatgc cagaatggga agggcgagat
     8161 ttgcaaggcg ttcatctttt aaaaacaatt ccggatgctg agcgcatatt aaaaacgcta
     8221 gaaacgaata aagttgaggc tgtaactatt attggcggcg gtgcaattgg actagagatg
     8281 gcagaaacat tcgtcgaact tggtaagaaa gtaagaatga ttgagcgaaa cgatcatatt
     8341 ggcacaattt atgatgccga tatggcggaa tatatacata aagaagcaga taaacataat
     8401 attgaaattt taacgaatga aaatgtaaaa gcgtttaaag gaaaagaaag agtagaacaa
     8461 ctggagacgg ataaagggac gtataaaact gatctcgttt tagtatctgt cggtgtacag
     8521 tcaaatactg attttcttga ggggacaaat atacgtaaaa accataaagg tgcaattgaa
     8581 gtaaatgctt atatgcaaac gaatgtgaaa gacgtatatg ctgctggtga ttgtgcaaca
     8641 cattaccatg ttataaagga aattcatgac catatcccgc tcggaacgac tgcgaataaa
     8701 caagggcgac ttgccggact caacatggtt gataaacgca gagcattcaa aggtacgtta
     8761 ggtacaagca ttattaaatt tatgaatctg acgctcgcaa gaacaggctt aaatgaaaaa
     8821 gaagcgaaag ggctaaacat cccgtataag acggtcaaag tagattcaac aaatatggcg
     8881 ggctattacc cgagtgcttt gccacttcac ttgaaattac tatatcacgc cgatacgaaa
     8941 caattattag gcggtcaagt aattggagaa gagggcgtag ataaacgtat tgatgttatc
     9001 gcgatggcac ttttcaataa aatgagtatt cacgatttag aagatgtcga cttaagttac
     9061 gcaccaccat ataacagcgt ttgggatcca attcaacaag cagcaaggag agcggaatag
     9121 cactttttta agtgctattt tttttgtgaa aggggaataa ataaagtttc actttatttt
     9181 gaatataccg ttcacccttg aaaacatagt acgtatcgct tatattgtca tatagtattt
     9241 gttttttaat aaagcaatga acgaaccagg gggcacagta tggcaattaa catgaataca
     9301 atcgaagaat ggattgctga atcaaatgca agaaacgaag aagacttagg aaacgttgtt
     9361 gaagagatga aagaagtatg tgtcggactt gataacgcga cattaattta tacgaaaaac
     9421 atattttgtt tcggtaagaa agtagaagta ttcttcttct tccaagatca cgtcgttatc
     9481 ggagaagaga aggaagagta tattgagatt gaaaaattaa agtatgatga cattacaaat
     9541 agcaacttaa aaacaaatga caaaaataca acgttagaac taaagttttc taacgggaaa
     9601 gctattaatt tagatagtct aaatgataac tacggtacga aaaactggtt atttgcaaga
     9661 caaattaaga gtatttttaa agtaatctag taaaaaaggc agaccttgaa aggtctgctt
     9721 ttttacttat ttcctattaa aaaaaggcac cctctttctt cataacattt cacgcttgta
     9781 aatcccgtct cataaaaaag gtttactaat tcttcggtcg tcttaaattt atccatatga
     9841 tattggattt tgaaagtttc agcgactagt aaaaaggatc cattcggttt taagacgcga
     9901 aatacttctt tcatatcatt ttttatataa gaatatgtat ttatttcgct tttaataatt
     9961 taactccttt aaaaaaagca cgccattaat cggcgtgctt ctaattatgc aaggaccctt
    10021 ttagccaatt tcgcgctcga tacgccccaa ccggaatttg aatgagtgaa gtttcatttc
    10081 cggcatcaat cccgtacaat tgatcgcatg aatttgtatc aaaacttagt aacggatgcc
    10141 cgcccatccc catagcggtc gcagctaaaa cgagtttatg aacgagcatg ccagcttcca
    10201 tttgatgaat tcgatatcct ctataaccta atttattttt atagtaatct ttatttccga
    10261 ttacatgtag acaaagtggt acttgaaaaa ggtttacgtt atccatcgtc atactggatt
    10321 gcagagaata acgaaggtct ccgtaccgaa ttggctgtat ggaatgtgtc ctactgttat
    10381 aagcgtaagc gccgttttct atgtctttta cgttataaaa acatccatat agtgagactc
    10441 gtgcgttttc atttaaatat ttgccatcaa ggtcgttgta ataagggaag gagaggctcg
    10501 ctgcttgtag tagagtagcg agctcggctg catcccattt cgttaaaatg aagtcagaat
    10561 caggtgaata tcgtttttta caaagttgta aaaaatcata tgataaacgt tccactttag
    10621 gtagctgcat agcgtgtgca ctatattgtt gtcgttcttc acgggtaaat gtttggaagt
    10681 gttctgttga ttcaatcata gaagctgcgt ttattttttt tatcatcgga tattcatcta
    10741 catattttga gcgaacgaaa tgctcatgtg ttaacggcgg gatttgctgc aacaagtcat
    10801 gagaagtaat agttttattt tcgtgatgat catcatgaaa ccaatctgta ttcggttctg
    10861 tacttaaagg aataacagca tacacacttt cttcaccttc tgacagtcca agtaaatgat
    10921 tcattgcccg atctagaaac tgaaaatata caccatttgt ataaccaaat tgttttgcgc
    10981 attcaagtaa ttgaccgatt agaacaccac tatctaatcc ttgcagacga tacgaaaagt
    11041 tattgtattt aaagaagttt ttccaaaaca tagtggatac aaatgcagca ccaaaacaag
    11101 aatgtatgtt acaacgattg ccgagtgctt ctgtaagata agaatcaaaa tttccttcac
    11161 gaagtaagat aagacggtgg tgcgcggcgt cgtaatggta aatgccgtct ggataatgat
    11221 caatttttaa atacatatat aattcatttg gatataaagc acccccagaa gggatgaatc
    11281 ttcgaaatag agtcgttgtt ttattatttt ctaggttagt agtaggctga cataattgtg
    11341 ttaaaccaaa tgagtaccaa agataatgac cgatttcctc taagttaggt ttagtagaag
    11401 aattccgcaa agttaatggg atttctaaag agagagggat tactggtaaa tttcgatata
    11461 atttataagg aagtggtgcg tcttcccagt caatctcttt atcggacgac ataatttcat
    11521 taatagaaaa atggagatga tgtaaaaaag tatcaggttg catcaaattt ccccctcact
    11581 atgaattatg gaaacggatg cggatgtgga tttaaacttt cattcgttaa aggctcagcc
    11641 caatatccaa gtgtcatcgg tacggtatac actctatcca gtcctgtaac ccgagtgaga
    11701 tggtgaccga acgtcatcgg taacatgcct ggaataatta cttttacaca atgtaagccg
    11761 ttcttttcta taagggggac cgtttgatct acaacaatta cttcaagtcc agattgatgt
    11821 aacctgttta aaagttgatg aagatcagat gttaaatcca tatcaaatga ttgtaatacc
    11881 ttcatttctt ggaacgtttg cactggagca tcatcacgta aaaggaagtg aagacgttct
    11941 tccgcttctt tcaatccgta cagcatacta tgatcttcca tttgcgaaac aagatatgga
    12001 tcttgtaaac agttttcata tttctctctt ttttgttcaa gctcttcatc tgttataagt
    12061 aacatgcccg ctatttcatg aattgcattt tttacagctc gaattggttc catatgtgcg
    12121 ccgccagcac agacgagatt cataccatct tgccttgtat ttttcgcaat gacccatatg
    12181 ctcggaatac catgttccat cgtcgcgttg aaaacgtata attcatatcc agtaattgtg
    12241 cgtaagcgtt ccaacattag ttgcaattca gtatcattgg ctgaactaag atcgagacgg
    12301 ggaagaggta attcggcata ccaagtgagc aaaaaggcgt cacgctctac aatttctaaa
    12361 atgccgtgaa aaattgcttc ttctaaacta ccaccaattg cacatccatt tgatgtttca
    12421 tacacgaaag catctctatg accaaggcta taataagcga ttgattctgg aactagaagg
    12481 ggcctgcttt gtaataaaga atatccccat acccagtttt gctcataatc aggatcaaac
    12541 ggcttaaatg gaaaactatc acgattgtaa tgttcatttg tatgcacacc aagtgtgaga
    12601 ggattcagtg caatatcttc tagctcacga aaactgccat gtacatttgt tttttttcca
    12661 cgaggcgaca taccgcaata gcgttctaat ccttctaaaa tagcggttgc ttcactaagt
    12721 gaaaatgaat gagtccggcc cgcgacacct tcatttccaa acagtaacgg catgtttata
    12781 atgacatcag caaacggtaa tagagaatgt tgcattttac cgtttaaaat accagtccgg
    12841 taatctaaat agtctctcgt taaaaatgtg tttagctcat gaatggaacg acagcgatac
    12901 gtttcagtac tcgttttcaa acttggttgt aaagaaattt gcgctgcatc tgctgtatcg
    12961 tcaggcaaat tgctgcatac cggacagaga gggtctggaa gaaacgaatt ccgggtacat
    13021 tgtaacgttt gtaagtccag taaaatgagt tcgttttcta aagaagaata tccatgagct
    13081 aatattttct ctgtttcagc atgaatgagc tggcacattt gtaacattcc attttgggtg
    13141 gcgcgtacat cacgcctcgt cacgttctct gcttttaatg catattttcg ttgtagttcc
    13201 cacatttctt tttgatcaaa gccagctata aaccggcgtc catcagcgca gtgggaacat
    13261 ccagttgtaa gaggcttcac gtaaggaccg ataatacctt caccaaacga agtaaacgcg
    13321 cgaagccacg gaatattatt tgagcgaaag ataagctcag catcacgatg tacggaagaa
    13381 ggagacccgt catgtaaaac gagagcaaga tgaatgtttt cagggagagc ttctgtaatt
    13441 gtatgctggc ggatgagtga atattgctta cacaattgct catgtacata gtctgtgagt
    13501 aggccatctc ctataagtag tatgttttga gtcattggtc atcctccttt gcaattaata
    13561 ctccatatac accgtctaag ttgtctctta aaaatgactc aatagctaaa tcaaaaacga
    13621 atggatacaa gttgttttcc gttaaatttt gcaaagcaac ttgtaaagac tgtacgcctg
    13681 gaatttcttc ctcttcttgt attgctactc taacaggatc cgtactatat aaaacaatgg
    13741 atgattccgg taacatatta gctttataag gaatctcttc attttgaata tgaaggagtg
    13801 cttgttgcag agcatttctt aatgcgagtg ttatattaat atttgccgca ccataccatc
    13861 tatcattaat accgatccaa acgacaggaa aaccaagtaa ctcctcactc attcctactt
    13921 taggtatttc atgaattgta gagagagcat cgtagtaaaa cctacaatgt ttatcatgaa
    13981 tttcggttaa ataaagctct gtaatctctt ctagcatatg tgattggcgt tcatataact
    14041 tattatttaa atgtttttgg agtgctcggt atacaccttc tgtcatcgtt tccccagcac
    14101 caataccgat atcagtatgt tcggggataa gacgatgaat catttcagct acatatgttt
    14161 caactcctgt taagccagct tcgcggcgtg cttcattatg agttaatcca ccgcaagtta
    14221 tagtaggaag gggagaggta ggtccgtctg ataatggatt tgcaacttga atattgcact
    14281 gtgataaagg caattggtgt aaatcttgtt catcccacat gtggaatatg ccagcttctt
    14341 tagaagttaa cgtatcaaaa aaacgaaaaa gttcagttga agtatattgt ccggaacgtt
    14401 gggcaaggtt ttcttgaaga ttttgcaccg tatcaattgt aaagatttca tcggttgcga
    14461 gaagatgttt tatgaaaggg tgccactttc cttcaagtgt ttccaagttt aataaaaaga
    14521 attgaggatt atgctgccta tgtgaatctt cagcgacaag tttaaataac tcaaaaacga
    14581 taacatttgc taacattgca gatgcaattg gtgagaaagg ttcaggtgga ttttcacttt
    14641 gtaaagtagt ttcgtgtaga cgatgccaag ctgattccca gcattcttca cggtctgcgg
    14701 ttacgacggg tccagctaaa ccaattcttg ataagcacat agctggtatg aaatttttct
    14761 taaattctct acaaatagta tggattgctc ttaaactttc aatatctcca ttttgggaaa
    14821 cgtataaaat ccagtcgaaa ggctcgaata cttcatgtaa agggcgatca attgtaatat
    14881 ctatttcttg aataagtaca ttgtcatcat ttgcatatgc acgttcgctt agttcatgaa
    14941 ttcgatcgta gtttgtttca gcacgatctg taacaagata atggaatgta ggtaaaccag
    15001 attctaataa agaagaaact agggaagtaa gcatatcacc agaaccaatt ataagcacat
    15061 ttgctgcgcg gtacctttcg aattttaaag cgcctgaatg ggaatcagct tctagaaact
    15121 caatttgcga agcgtatctg tcgagtaatg cactgtttaa ttcgtgggga gcatcttggc
    15181 ttacatcacg aatgaaacca ttttcatata aaatctctcc aatttcaaat acacgatttt
    15241 gataggggag agggagacca tcggttattt ctgtcaaaga atgattaccg ttaaacatag
    15301 gcattaattt ctcaatccag tcataaattc catcaccatc catacggaat gaactggagt
    15361 tatttcgaaa gtaaacaccc ccgtttgaat cggggaggaa gaaagtatcc ttatttgctt
    15421 taagttttgc atgaactgga aggttattca tgtttatccc ccttacgttt taggcataca
    15481 ttgttagtct atgtagtgtg atttgtcccg tatgaacata atgaaaaaag gctgtagaat
    15541 gattcattct acagccttta atagattaat aatctatcaa ccttctaata ataatgattt
    15601 tggatcttca agcatatctt taacagcaac aaggaagcta actgcttctt taccatcaac
    15661 aatacggtga tcgtaagata gtgcaaggta catcattgga cggttttcca tacgctctgc
    15721 atcaattgca actggacgta cttggatttt atgcatccct agaataccta cttgtggact
    15781 atttaggatt ggtgtcgaca ttagagaacc gaacacgcca ccgtttgtaa ttgtaaatgt
    15841 accaccttgt agctctttta atgaaagttt attatcgcgt gctttcagac ctaaattacg
    15901 aatctcgctt tcaatttcag cgaagttcaa ttggttagca tcgcgtacaa ctggaacaac
    15961 taatccatct ggagctgcta ctgcaatacc gatatcatag aattttttaa tgataagctc
    16021 atcgccttga atttcagcat ttaataatgg gaactgtttt aatgctgcaa caactgcttt
    16081 tgtgaagaat gacataaagc caagacgtac atcatgtttt ttctcgaaag catctttgcg
    16141 ttctttacgt aattccatga ttgcactcat atcaacttcg ttaaatgtag ttaacattgc
    16201 agatgtttgt tgaacttcta caagacgttt tgcaattgtt tgacggcggc gggacatttt
    16261 cacacgctca actggttttt caaattcagt ttttgcaact ggagccgggc tttgttttgg
    16321 agcagctggt gcttcttttg gcgctgcagc gtgagcttgt acatcatgtg gtctcacacg
    16381 tccaagtgga tctgtgctac gtacttcgtt taaatcgatt cctaattcac gagccatttt
    16441 gcgagcagct ggtgatgcga taggacgatt tgtatttggt aaaccttgca acgctttatt
    16501 ttgttcagca cttggagctg ctgctttcgg tgcttcagta gtttcttgtt ttggttgctc
    16561 attagccgga gcaggtgtgc ttacttcaac cgctgcgccg tttgcatcta aaattgcgat
    16621 agtagcacca acttcaactg tatctccagg ttcgcctagt aacttcgata caatacctga
    16681 atcctctgca atgatttcta cattgacttt gtcagtctca agctcaacaa cgctgccacc
    16741 tttctcaact ttgtcgccta cgttgataag ccattgtgaa atagttcctt ctgaaataga
    16801 ttctgcaagc tcaggtactt taatttcgat cattttaaat gtcctcccct tatttgccta
    16861 acggtgtgtt ttatcttctt taatcttcgg taatctccat ttgttagcct ggctgtggca
    16921 gactatctgc cacagccaag cctgaaaaac tcattgttac tttcagttgc tgaaaacttc
    16981 aatttcttgt ttatcttgac ggaagttgta cttcacatct aaagcgtgtg caacgattaa
    17041 ttcttgctca gctttgtgag cgaatggatc gccaccagat gggctagaac gatccgggcg
    17101 tccaatgtaa cctgttttca ctttatcccc agctagttcg aacagaattg gagccatgta
    17161 atgccatgcg cccatattac gaggttcttc ttgaacccaa atgatttctt ctaagttttt
    17221 aaagcgttta ataatagatt gaactttttc agcagggaat gggtacaact gctcgatacg
    17281 aaccatatga acttcatcta ggctgtactc atgcttacca ctttcgattt ctgctgctaa
    17341 gtcaattgcc attttacctg tacttaaaac aagacgtttt actttatttg gtttcgcacc
    17401 aaggtttcct tgttctaaag caggttggaa acgtccttca cttaactcac tacctgtaga
    17461 aagtgtaagt gggtgacgta ataagctttt cggcgtcata attactaatg gtcgaacagc
    17521 ttctgttcct aagatagatg cttgacggcg caagatatgg aagtattgtg ccgcgctcgt
    17581 taagtttgca actgtccagt tgttctccgc agctaattgt aagaaacgtt ctggacgtgc
    17641 actagagtgt tctggccctt gaccttcata accgtgtggt aatagaagaa ctaaaccaga
    17701 tttttgaccc cattttgctc ttcctgctga aacatattga tcaaataatg cttgcgcagt
    17761 atttgagaag tcaccgtatt gagcttccca catcacaaga gtttctggag caaatacgtt
    17821 gtaaccatat tcgtaaccaa caacagcagc ttctgataac ggactgttat gaacagagaa
    17881 tgatgcgtta atgttcggta aacggtgtaa tggtgaatat gtttcgtttg tatcagtatc
    17941 gtgtaatacg atatgacggt gcgcgaatgt accacgctgt gaatcttgac cagttaaacg
    18001 aattggcgta ccttcttgca aaatagaagc gaatgctaac gattcagcaa gtgcccattc
    18061 aattttaccg ttctcttcaa gagcatcttt acggcgctca agaattttct tcacttttgg
    18121 atatacgtta aagccttcag gccaagataa tagtccttca ttaattgcac gaagtgattc
    18181 aattgaaaca ccagtgtcaa tcggttgaat tccttttgca acaacctctg gaactttaac
    18241 gtgaattgtt gcagcactcg tatcagctgg tggcacttgt gcgtattcag cctttaattc
    18301 ctcttgtata aactgagtaa ttgtttcaac ctcatctgca ttcagaacgc cagcagattg
    18361 taattgatct gcataaattg ctcttacagt tgggtgattt ttaatttttt tgtacacttg
    18421 tggttgcgta actgctggat catccatttc gttatgacca tatcggcggt aaccgattaa
    18481 atcgattaag aagtcctttt tgaacagcgt acgatattgg atcgcaaggt ttgcagcagc
    18541 aagacaagct tccggatcat cagcattcac gtgaacaatc ggaatatcga aaccttttgc
    18601 aaggtcgctt gaatatttag tagaacgaga atcatagcta tcagtcgtaa agccgactgc
    18661 attatttgcg ataacatgaa tagttccgcc agtttggtat gcattcaatc tacttaagtt
    18721 gagtgtctca gacacaacac cttgaccagg gaatgcagca tcaccatgaa ctaaaattac
    18781 gaatgatttt gtagtatctt gttctggaag accagatttt ttacgattct cttgagctgc
    18841 acgtgcgaaa ccttcaacaa cagggttaac gaactcaaga tgactcggat tatttgctaa
    18901 tgtaacacga gtgctaacct cttcattacc aacgacttgt tctctaccta aatggtattt
    18961 cacgtcgcca gtccagccag catttgccac tgcaccttct atttttgcat gtttgaattc
    19021 tgcaaacatg tgattatatg gcttttctaa tacgtgagcg agtacgctta gacgaccacg
    19081 gtgagccata ccaatcatga catcttcaac gccgccttta gcaccttctg aaacaatttc
    19141 atctagtaca ggtacaagca tatcaacgcc ctctattgag aaacgctttt gaccaacgaa
    19201 tgttttatgc aagaattgct cgaaaccttc aacagcagtt aaacgtttta aaagagcagt
    19261 tcgtttttta tttgataatg gttgacgcaa tgaatttgat tccaccattt gatgcaacca
    19321 cgcgcgttct tcactatctt gtatatgtga gaattcataa gctaaagatt ttgtataaac
    19381 gtcttttaat ctatgaatta catcaagtgc agtgtgaata ccctctggtg catcttgcca
    19441 tactgttttt gctggaatcg ctttcaagtc agcatcgctc agttcgttca ttgttttctc
    19501 gataagagat tgtccgtttg cagcatcttc catcggatta atgtgagcca atgtatgccc
    19561 gaaagaacgg atctgttcaa caagttgaac gactttaaga atcttttcaa tgttccctgt
    19621 gttttgagga gaaaaatgtg ttgctgtgtt gtcccctgtt acgacatcat cttgaaacga
    19681 aggagctcca aaaatttcaa aaagctcttg taattccgga tcaacagaac ctgctccagt
    19741 tacgtaaaga tcatactgtt caataacata accaaggttc ggaccatgga acttggccca
    19801 agggtttgtc gttgtattct tcctcgtcat ttgtttaaac ctcccaatgc atataatcct
    19861 ttttccatac aaaaaggtgc attttgctct tttcaataat tgatgaacca ataatcaatg
    19921 taaatgtttt tctttactct tatgttatta caataattta cataatacca aacactatta
    19981 cttatctgtt ttgtaaaaaa acattcacaa taacttatca cccaagttaa tctttcatgt
    20041 tataaagtaa tttcacggga aaacggggtg gatatatttg gtatacctac attaatacct
    20101 ataattgttg catttaaata taagtataac tatcagaatg tttcgataaa gtttagttcg
    20161 aattatgtat attggaataa taagcgcttt cattgatatt atacaacaat ataacggaat
    20221 atagtataaa aaataaaaaa ttatgaattt accataaact ttatctcgat agtgttaaat
    20281 atcgaaagga aaatgaagga tttctacaaa aaaagtggct atacataaaa aatgcttcat
    20341 aaaccgttag tttctataaa tatggcgaaa aataacgtaa aaacaatagc gtatttcacc
    20401 cgataaagag cagaatgaaa cattttaaaa ggataaaaca aatatggaga tattaaattt
    20461 tcataaaaac ggagaggaga tatagtaacg gctatataca ttgttccatg tttcatttca
    20521 aaatagacgt gctgaatttg aaaaagtttc ttctatataa atagaatgaa aaatagacga
    20581 aatgaatgta aaggaaactt gacgtaaagt ttcctttaca tatatactcg gtataaggaa
    20641 ggagggagaa atttccttgg aaaataaaat ggttgaatac cgaaaaaaat ttggactatc
    20701 tcaagaaaaa ttggctgaga aacttggagt ttccagacaa accatcattt caattgaaaa
    20761 gggaaaatat gatccatcac ttccgttagc atttgaaata gcaaaaacat ttcagacaac
    20821 gatagaacat gtatttattt atgaaggaaa ggaagagggg gaataaagat gaactattca
    20881 caaaagtact tcgttatgat gggaattatt tttctattta tgagtggatt tatgatatta
    20941 acaggtataa tgacgcattc tgcaccaccg gctccaacgt atacattgct tgcgatgatg
    21001 attatgtgtt tttgcctaag ctacttgcac ccgcaattta aagaaaaaga tgagcgaatg
    21061 aaactcattc gttataaagg aatgttcttc agtttttttg cactaacggc atactatctt
    21121 cttttctcta ttggcttaaa cttaaaaata atgacgctat ctgcggttga actattgaat
    21181 atattaatgg cacttacgat gagtacagtt tttatatcgt ttgttgtttt atcgaaaaga
    21241 tattaagatg taaaagagaa aggaagatta acatatgcaa atgatgtatg cttttggcat
    21301 ggggcttgta ttatttttag ccgtattctt atttattcgt aaagacgttc aaggcggaac
    21361 gttaacgaaa cgaggatttt ataaaatgat cggctgctta gttgttatgt ttatagcgat
    21421 tatcgtaatg atcgttttaa taaatcagtc attatagaac ttaaaaacgg aaccttactt
    21481 ttgtaaggtt tttctttttg gaaataaatc taaaaattac cataaaatcc atttgctatc
    21541 tatatcttgt attatataat ccaataaaat gatagataag gagaatagta tatgaataaa
    21601 aaagctatct tctttttatt aacatgtcta ctacttatag ctagtattac ttatataata
    21661 tgtaacaaat gagaacaagt tccacctata ttagtatagg aggggcatga atactacgtt
    21721 acgaatgaac ctgccaaagc agaagaagcc gggcaaaaac ttggagaagt gacgaagaaa
    21781 attgaaacaa gcaaacagcc tactaaagat agtgaatcca acgtattaga agaaaaaaca
    21841 gaagtatttg aaataatttt agaagaagag gatgaaaggc cacctatact cgtaaaagaa
    21901 cctactagtg aagaatatag agtagcaagg ccgatgttaa aacaagtact ataatgaaaa
    21961 ggagacccat atgcagagag taacttcata tccgtggtcg ttaagaaaaa tatttgtctt
    22021 tttcctttgc tttattctgc ctcctatcgg tgccatttac attttgatga atagagaggc
    22081 gctacaaaag agagactaca ttttatattt attatttgct gctattaata tatcgctttg
    22141 gttatcattg atgatttttg ataggagtat gtggatggta gcggggcatg atgtgcttgg
    22201 tgtaattgtt attatttttt cgaatatgaa taagagctaa cccagcaatc ttaaagttgc
    22261 tgggttttat tttgctattt ataatgaaga aacaaatttt taatagagag tagtgatgtt
    22321 atgagatgga aagcaggaac gtttgaaaaa atagaaacga atgactcatc tgttgagaaa
    22381 attataaaca cgtttaagga acaaaactta aatggtggcg caataataag ctgttttaaa
    22441 gtacataacg aaaatttttt caaagaaata ccacattcga aagatggata cgagcacttc
    22501 tttagaagaa tcttcaactc tttagatata atacataact tagaagagtt aaaaatacat
    22561 acatcagaaa aatataaatt tcattttaaa gaacatctgg tagtcatgct tgatggtagc
    22621 attgccgctc aaattttgtg gggcggagca tatgaaggat ttaaggaacg accagttatc
    22681 gcaaaacaat tagcggtcaa tgtatgtcaa tatatgttcc aagatcgata cgaagatatt
    22741 aaagtgttcg aaagctatcg cccttggaca gattggtttt acgatgttgc gtgggatgct
    22801 acttggatgg tgttagatag taaggagcat aaaatgtggt tagtttgtgc tacggatacg
    22861 gattgataga agagggggct ttgtagaaat gctacaaggc cctttatctt ttgggaatga
    22921 atagaaaacg aatcatataa atgctatact aaaaaatgtt tgtaatgtca gtttcatact
    22981 attgtataat gctgacttac tagaaaagat aagaggagaa tgaacgtgaa aaagatacag
    23041 aaattattgc tgttaatgat ggtagtagga ttaacagtag gtgttttagc agggtgtgca
    23101 aatccgaaag atactacaaa agaattttta acagcgatac aaaaaggtga tgtagaaaag
    23161 gctcgtacat ttgttgagag tgacaaggaa tttaataaac taaatgaaaa aacagatgat
    23221 gctgaggcaa aagcgatgct gagtgcaatt acgaaaaact ttaaatttga aaagccagaa
    23281 gaagtatcga aaaaggatga caaagcagaa gtgaaagtga aaattacatc tgctgatcta
    23341 tccgttgctg taacaaaagc agtgggagaa gttatgccaa tggccttcgc tagtgctttt
    23401 agcgaagaca aagaacaatc tgaaaaagca atcgaaaaaa caatgacatc aactatcgtc
    23461 aaaaacttag cggataaaga tgcagcaatg gcaactcgcg aagttacatt gaacttaaag
    23521 aaaaacaaag atggc
//
