LOCUS       NZ_CP036072            22732 bp    DNA     linear   CON 25-JUN-2024
DEFINITION  Bacillus wiedmannii strain JAS07/5 plasmid p536.
ACCESSION   NZ_CP036072
VERSION     NZ_CP036072.1
KEYWORDS    RefSeq.
SOURCE      Bacillus wiedmannii
  ORGANISM  Bacillus wiedmannii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 536465)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 536465)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.157x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018741285.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:17:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,980
            CDSs (total)                      :: 5,827
            Genes (coding)                    :: 5,631
            CDSs (with protein)               :: 5,631
            Genes (RNA)                       :: 153
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 88 of 196
            Pseudo Genes (incomplete)         :: 110 of 196
            Pseudo Genes (internal stop)      :: 59 of 196
            Pseudo Genes (multiple problems)  :: 52 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:47:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 63673
            Orig. end                         :: 86405
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036072.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22732
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22732
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22732
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12732](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12732
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    608..622
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 24.36"
                     /tool="antismash"
     gene            1051..1266
                     /locus_tag="EXW41_RS27470"
                     /old_locus_tag="EXW41_27875"
     CDS             1051..1266
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167046.1"
                     /locus_tag="EXW41_RS27470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27875"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_001167047.1"
                     /transl_table=11
                     /translation="MQIRENNNSNEILIAAAASAIEQMKYEIAQEFGVTLGPDSTARAN
                     GSVGGEITKRLVRMAQEQLSGQYKIH"
     gene            complement(1342..1755)
                     /locus_tag="EXW41_RS27475"
                     /old_locus_tag="EXW41_27880"
     CDS             complement(1342..1755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016107601.1"
                     /locus_tag="EXW41_RS27475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27880"
                     /product="hypothetical protein"
                     /protein_id="WP_088062850.1"
                     /transl_table=11
                     /translation="MKKVILAGALGIAVLSGMNLPGAEAPIASAATTNLEIQEVTKYYS
                     MSSYEVSQKESFNLNKGEELTVFVQNSGFPISYTVFDTDDQVIGTYNANSPYGRVFKAQ
                     KDGNISVQFQAGVNSSYMKKMNFTAKFAVSKFN"
     misc_feature    1835..1853
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.68"
                     /tool="antismash"
     misc_feature    complement(1838..1853)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            2244..2405
                     /locus_tag="EXW41_RS27480"
     CDS             2244..2405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969597.1"
                     /locus_tag="EXW41_RS27480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_168216123.1"
                     /transl_table=11
                     /translation="MIDYYQIFLFTMAGIALFFYIQHAGKPTKRNKWKFFVVVFLFFLL
                     NYLFLRFI"
     gene            complement(2500..2961)
                     /locus_tag="EXW41_RS27485"
                     /old_locus_tag="EXW41_27885"
     CDS             complement(2500..2961)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002017099.1"
                     /locus_tag="EXW41_RS27485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27885"
                     /product="hypothetical protein"
                     /protein_id="WP_088123101.1"
                     /transl_table=11
                     /translation="MRKFGKVLLVGTLALGSLTAMNIETPKAHADGASEYCRYICGPSE
                     TVNNFTIQLHATEYGFGQNVIAKVTNDRTESVNYKVSIEKQYETGWGYYGTWFNWNSML
                     PAGTNEEIVTFSGNGEDIGDAGTFRYKVEITNADGSVDTIYTAPMTLVN"
     gene            3368..3550
                     /locus_tag="EXW41_RS27490"
     CDS             3368..3550
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EXW41_RS27490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179196644.1"
                     /transl_table=11
                     /translation="MICRTIRVQVPWEFVSTVTEENMKQKLESTPGLLVNLFKTCKRNH
                     SKSKESEIERIFREI"
     gene            3962..4255
                     /locus_tag="EXW41_RS27495"
                     /old_locus_tag="EXW41_27890"
     CDS             3962..4255
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209597.1"
                     /locus_tag="EXW41_RS27495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27890"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_016136180.1"
                     /transl_table=11
                     /translation="MKTVVTDRDLAEIREEDVDVLKVMAHPVRLQIVNELMHHKMCNVT
                     QLTEILRLPQSTVSQHLSKLRGTVLRAERRGLEMHYYIDNAKARQIVGILGF"
     gene            4507..4761
                     /locus_tag="EXW41_RS27500"
                     /old_locus_tag="EXW41_27895"
     CDS             4507..4761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136181.1"
                     /locus_tag="EXW41_RS27500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27895"
                     /product="hypothetical protein"
                     /protein_id="WP_088062852.1"
                     /transl_table=11
                     /translation="MYIKKLILAGALGFIILGCANIAGEKVTKANAASIETDRVTMEGP
                     IVELGEHDFYIKSQKYNEDFDNPISVEVDYKRNVKIGIK"
     gene            5175..6881
                     /locus_tag="EXW41_RS27505"
                     /old_locus_tag="EXW41_27900"
     CDS             5175..6881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788193.1"
                     /locus_tag="EXW41_RS27505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27900"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_215559139.1"
                     /transl_table=11
                     /translation="MKNKTSFVRVGVTTGVLLSAIMPFSGAYAATEDLKVETKEDTFRA
                     GNLTAPSQKPAENVAKDALKGKTEQALSSQQINTESKVNYNVTQSRKSYDGTTLVRLQQ
                     TYEGRDVYGFQLTAHINDEGVLTSVLGDSAQKLQQQEDLNQSMTLSKEDAKNQIFNLYG
                     NDLTFIEEPEIKEVVYVDENTKKARNAYQINFSASTPEYVSGTVLIDAFNGNLLKEIVQ
                     KLGIQVDSSIVQSATSNKSQDPSKLTGAGKDDLGINRTFGISQRSDGTYILADYSRGKG
                     IETYTANYKDYNNYKRNAWGYLDDLVTSNSTNFTDPKAVSAHYLATKVYDFYQEKYGRD
                     SFDNNGQKVISVVHGWNTNGTNKGNPKQWFNAFSNGAMLVYGDPIVKAFDVAGHEFTHA
                     VTRNESGLEYAGEAGAINEALSDILGVAVEKYANNGNFNWTMGEQSGRIFRDMKNPSSI
                     SSRYPEDYKHYNHLPIDADHDHGGVHTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMF
                     DIFYYVNTDELNMTSDFKELKEGCIRVATNLYGKNSSEVQAVQQAFKAAYI"
     gene            7131..>7274
                     /locus_tag="EXW41_RS27510"
                     /old_locus_tag="EXW41_27905"
                     /pseudo=""
     CDS             7131..>7274
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251810.1"
                     /locus_tag="EXW41_RS27510"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27905"
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /pseudo=""
                     /sec_met_domain="Peptidase_C39 (E-value: 2.1e-13, bitscore:
                     45.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFESFPYIKQHDLQDCGPACLAMISRHYGLSLSISKIREVSGTD
                     LKG"
     gene            7389..7751
                     /locus_tag="EXW41_RS27515"
                     /old_locus_tag="EXW41_27910"
     CDS             7389..7751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282130.1"
                     /locus_tag="EXW41_RS27515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27910"
                     /product="hypothetical protein"
                     /protein_id="WP_088062855.1"
                     /transl_table=11
                     /translation="MYTCNQCGTGMIMQLQDRYREYCPKCEMPRPSSLMYYNLYELLEY
                     MEVNEYLSKESMLHNFLKWEFELTEGRIFKLHLDVERYDQIGDENFTKQLETYMKGIRL
                     KLNVKYEDDYIWVKVN"
     gene            7819..8148
                     /locus_tag="EXW41_RS27520"
                     /old_locus_tag="EXW41_27915"
     CDS             7819..8148
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389842.1"
                     /locus_tag="EXW41_RS27520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27915"
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="WP_088062856.1"
                     /transl_table=11
                     /translation="MEDLQKEVIRFRDERNWGQFHNAKDLAISLNLEAAELLETFQWKS
                     SQEAKETKMQEMKEEIADVMIYLLLLSDQLNIDLEEAVRSKLTKNAEKYPVEKAFGKNK
                     KYNEL"
     gene            8271..8738
                     /locus_tag="EXW41_RS27525"
                     /old_locus_tag="EXW41_27920"
     CDS             8271..8738
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016135742.1"
                     /locus_tag="EXW41_RS27525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27920"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_088062857.1"
                     /transl_table=11
                     /translation="MGISIEKLDKKMDNRESIKEIIELWNLNAIETADCELEESHKKGI
                     EEQLMELIQSRYGAVFVVTDEINRLIGYGIGSIKQDLVTNMLYGQIEEVYVKTDYRRKQ
                     IAQNLVEKMSNWLNQENVSLIHVYVDLANKLALNFWENTGFEKEFFLLSNS"
     CDS             9115..9282
                     /gene="allorf_072788_072955"
                     /locus_tag="allorf_072788_072955"
                     /protein_id="allorf_072788_072955"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MYKLQLNSIERRGRRNMKKLEAGKVKAYGSFMAVTLAKKNKPGDG
                     TRTKGIRKGL"
     CDS_motif       9115..9222
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence:
                     MYKLQLNSIERRGRRNMKKLEAGKVKAYGSFMAVTL"
                     /locus_tag="allorf_072788_072955_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9223..9282
                     /prepeptide="core"
                     /locus_tag="allorf_072788_072955_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2007.3"
                     /monoisotopic_mass="2006.2"
                     /core_sequence="AKKNKPGDGTRTKGIRKGL"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MYKLQLNSIERRGRRNMKKLEAGKVKAYGSFMAVTL"
                     /leader_location="[9114:9222](+)"
     CDS             9319..9438
                     /gene="allorf_072992_073111"
                     /locus_tag="allorf_072992_073111"
                     /protein_id="allorf_072992_073111"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKKLEAGKVKAYGSFMAVTLAKKNKPGDGTRTKGIRKGL"
     CDS_motif       9319..9378
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKLEAGKVKAYGSFMAVTL"
                     /locus_tag="allorf_072992_073111_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9379..9438
                     /prepeptide="core"
                     /locus_tag="allorf_072992_073111_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2007.3"
                     /monoisotopic_mass="2006.2"
                     /core_sequence="AKKNKPGDGTRTKGIRKGL"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLEAGKVKAYGSFMAVTL"
                     /leader_location="[9318:9378](+)"
     CDS             9475..9594
                     /gene="allorf_073148_073267"
                     /locus_tag="allorf_073148_073267"
                     /protein_id="allorf_073148_073267"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKKLEAGKVKAYGSFMAVTLAKKNKPGDGTRTKGIRKGL"
     CDS_motif       9475..9534
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKLEAGKVKAYGSFMAVTL"
                     /locus_tag="allorf_073148_073267_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9535..9594
                     /prepeptide="core"
                     /locus_tag="allorf_073148_073267_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2007.3"
                     /monoisotopic_mass="2006.2"
                     /core_sequence="AKKNKPGDGTRTKGIRKGL"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLEAGKVKAYGSFMAVTL"
                     /leader_location="[9474:9534](+)"
     CDS             9631..9750
                     /gene="allorf_073304_073423"
                     /locus_tag="allorf_073304_073423"
                     /protein_id="allorf_073304_073423"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKKLEAGKVKAYGSFMAVTLAKKNKPGDGTRTKGIRKGL"
     CDS_motif       9631..9690
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKLEAGKVKAYGSFMAVTL"
                     /locus_tag="allorf_073304_073423_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9691..9750
                     /prepeptide="core"
                     /locus_tag="allorf_073304_073423_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2007.3"
                     /monoisotopic_mass="2006.2"
                     /core_sequence="AKKNKPGDGTRTKGIRKGL"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLEAGKVKAYGSFMAVTL"
                     /leader_location="[9630:9690](+)"
     CDS             9786..9902
                     /gene="allorf_073459_073575"
                     /locus_tag="allorf_073459_073575"
                     /protein_id="allorf_073459_073575"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKKLEVGKVKGYGSFMAVTLAKTKKPGDGTRAKGVRRR"
     CDS_motif       9786..9845
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKLEVGKVKGYGSFMAVTL"
                     /locus_tag="allorf_073459_073575_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9846..9902
                     /prepeptide="core"
                     /locus_tag="allorf_073459_073575_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="1964.3"
                     /monoisotopic_mass="1963.2"
                     /core_sequence="AKTKKPGDGTRAKGVRRR"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLEVGKVKGYGSFMAVTL"
                     /leader_location="[9785:9845](+)"
     gene            10001..10279
                     /locus_tag="EXW41_RS27530"
                     /old_locus_tag="EXW41_27925"
     CDS             10001..10279
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="EXW41_RS27530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27925"
                     /product="PqqD family protein"
                     /protein_id="WP_016135746.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.4e-11,
                     bitscore: 38.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.1e-09, bitscore: 30.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKKNSNTVTSIANEEETIVLHISEGEYYGLEGAHKEIWDNFNQ
                     NLFEKKSIVEEFLSKFDNSKEEIQKLVDESVMDLINYKLIMVVDKYE"
     aSDomain        10016..10261
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW41_RS27530_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.40E-12"
                     /identifier="RREFam002.1"
                     /label="EXW41_RS27530"
                     /locus_tag="EXW41_RS27530"
                     /protein_end="87"
                     /protein_start="5"
                     /score="38.5"
                     /tool="antismash"
                     /translation="NSNTVTSIANEEETIVLHISEGEYYGLEGAHKEIWDNFNQNLFEK
                     KSIVEEFLSKFDNSKEEIQKLVDESVMDLINYKLIMV"
     gene            10272..10748
                     /locus_tag="EXW41_RS27535"
                     /old_locus_tag="EXW41_27930"
     CDS             10272..10748
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024862.4"
                     /locus_tag="EXW41_RS27535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27930"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_016135747.1"
                     /sec_met_domain="PF13471 (E-value: 3.7e-12, bitscore: 41.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNSKEYFVALHNLVRGLLIEDSFDVVFNKVSIQFFPMYESAKRR
                     KAMPINIKELITFSKYLYEMDEQDALIASCVSISLTNQIVLYSNGIDAKLKIGFKKIDE
                     KLHSHAWVELENGEVIDPQNHLGKLQVMHIFKMRDGVERWVTENENVDSYVGRK"
     gene            10714..12732
                     /locus_tag="EXW41_RS27540"
                     /old_locus_tag="EXW41_27935"
     CDS             10714..12732
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="EXW41_RS27540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27935"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_179196651.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.7e-15, bitscore:
                     52.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMWIAMWGENNTIKKQWNKNLRNWLSSMKISNQLNFDREGFFLS
                     EVDFSYKDSHKKTNEQISFLATPLIMNGVLSDSLKHSYVENLTSKARGNLYKGLTSNID
                     YQLQNANGDFTITYVDRNMDNLVIANDIYATRPIYYYKHPNDDFFCASNDLRTLLLNYE
                     IPFTVNYNACLNYPTTQFAISEAEYSNETFFKGIYRLPPASILQWNKNDKLSIRSYWGL
                     NNLLNKVKHTNITDYVDEFRQTMLDVVQLRISDKKTILDVSGGLDSGNILGAAIANGSS
                     SSIFGVNLSFESNDMSFSHDKELVTKLLQDLNIEHAIIMGDDINKILNAEIGRDPMWYI
                     DGPDPRGNPLYDEVVAAISIEVGANRSISGDGGDYVASGEELVIDSLLRQKKFKEAVSK
                     LWNWSDKKVGGFLDKTFTYGIAPFIPGLNERLYYKTVWAEKVEANMPFFTTEHIERENK
                     GNQREYEQYKKSKDFKLWGHRYHYDYLYPRARCLDTTRVATDYMYPFYDKKMIELSFCV
                     PPEEHYDLLEGHKNGYYKGSKQLMRKAFKDVLPDYLLNRKIKTTYAHMARKCLLNEKHN
                     ILQLFSKDKKNFVAELGIIDKEKYRDHLIAMLIRSNDPNNDLGMSFQYLRSVLELEIWL
                     QEVEKGRDYILERSKPVDPRNIGKCIFSSELKQATFY"
     gene            12772..14586
                     /locus_tag="EXW41_RS27545"
                     /old_locus_tag="EXW41_27940"
     CDS             12772..14586
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="EXW41_RS27545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27940"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_215559140.1"
                     /transl_table=11
                     /translation="MLNFKNNMSIAFFLGKIIWKSSPILVIVLLVLLSAEGLIVAIQLF
                     ATREILNGIKNANPSDTYVYIWGIVYCSTFVIGIFSVSITSWIQKLLGEKSMLTINTTL
                     LEAIEKMPGMRFFEEIKYRDKLETLRDSTSWLPMQIVESTGSVITGGISLISIIIVVGT
                     LSPLLAVILIVSAIPFVIYANKFTAMEWVYENEFASNRRKMSYYRDNLLMKNTVQEVRL
                     FNLGEFFLKQYKETFDVVFSAYKKIQTKSLIPITLTGLLSGGVSGIGYLWVTYKISNAS
                     LTIGDIALYLTALFQLNVLLRNVSNEFVETLELWRMGGDFHDFVKLKPDVQISPNSKFV
                     DLSEMNIEFKNVSFSYSTNKEHKILRNLSFRLNARQSTAIVGMNGEGKSTIVKLLCRFY
                     DPDEGEILINNINIKEIEIQHLRKHISAIFQSFGKYGLAIDENIGIGDYESIENKKQIQ
                     EIAKRVGIHEKINSYSDSYKTMVGNEWNGIEFSGGQWQKIALARAFFRNASTLIMDEPT
                     AALDIKSEEQLYNQFYLLTRQKTVLLISHRFSTVKMVDSIIVIKDGEVIEQGSHEALMD
                     KQGEYAKMYLMQASSFSLEGTVKNEKSQ"
     gene            14570..16378
                     /locus_tag="EXW41_RS27550"
                     /old_locus_tag="EXW41_27945"
     CDS             14570..16378
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="EXW41_RS27550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27945"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088062861.1"
                     /transl_table=11
                     /translation="MKSLNKVYHTYKFTRETLTSLKMLWKADKVGFTYIMLIKILESII
                     QPLLIWLSTKVIDDLSKDPAALLNSNFTFWIIITFIILTITADLFNPFFEVKKRLLVAK
                     LQMYIDVLIMKKANTLESLEFFEDKELYNKIRSFRNNEYWITMWIDLIMKSFGGTVKII
                     ASVALLFSLLPWYPFLLLVVSIPKLIKEVNLNQATFEGRPELMELRRRAEYYTSVPLLP
                     QLAQEVKLFHLTPFFKEKYVKTVQKLSATLSKDQRKLAVHSLLWGLIQACVISFSIIFI
                     IYSAINNEVSIGSVVLFLGMTIQLCEGVNEYFALIAIGAREGRHLRNLLNFIQFPNPKR
                     VNSSLVESQEKDSGFYLSQVDFSYQNSEESSLSIKKLHIPQGKITALVGENGAGKTTLI
                     KLLLRLYNPSQGSIYYNNKNLNDYDSTEYKKKCTAVLQDFVRYEMLLRENIGLGDVKNI
                     NNIHEIQLASDKSNVKELLPTLTDEYDTQLGKLFGGQELSGGQWQRIAIGRAFMRDKEA
                     EILIFDEPTSALDPYAEDEIIRVLSNLADNKTVIIVTHRLSTAKLANHIIYLDKGHVTE
                     QGTHEELIIKDGKYAELYSIQAKKYS"
     gene            16480..17757
                     /locus_tag="EXW41_RS27555"
                     /old_locus_tag="EXW41_27950"
     CDS             16480..17757
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015380.4"
                     /locus_tag="EXW41_RS27555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27950"
                     /product="clostripain-related cysteine peptidase"
                     /protein_id="WP_088062862.1"
                     /transl_table=11
                     /translation="MKKTYRILLILMFLIGVCSLVEDNVIKVSADTNKVNKAKYTVMVY
                     LDGSSLESDFELASEDLKEMLKIGSSEEVNIVIETGGAKKWHTPAINPETNQRWIIQKD
                     SLQLIEDVGLKNMGESSTLSDFMIWGMEKYPAEKYAVILWGHGSGSVYGYGHDERFGLD
                     PLTLPELEKTFKDTYEKTRKKLEIVAFDACLVTNLETLSYINQYANYIVGSEDMVPGHG
                     LNYIYTFEKLLNKPNMNGAELGRIIADGFYKQAIENEEEDDIAMSVIDLSKVKPITKAF
                     DDIARLLKVDVLNDDKFQSILTARRNVEEYGKMDGPEDSEMVDLGDLAKQMYSQYPFYS
                     RRIMSAVDQAVVYNVKSPWKKATGICLFFPLGDRERFDEKLNLYKNNNFSKDYYDFLEI
                     FIGNLKNNQFMNVSNESLNTNIVKKI"
     gene            complement(18218..18826)
                     /locus_tag="EXW41_RS27560"
                     /old_locus_tag="EXW41_27955"
     CDS             complement(18218..18826)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783231.1"
                     /locus_tag="EXW41_RS27560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27955"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_088062863.1"
                     /transl_table=11
                     /translation="MYISNRIGLFSWIATCLYFLIEPFFIFTSTAPYNYLHHAMSDLGV
                     TTCGEFTYEIAPYEICSPNHFWMNLLFILNGITFCIGVLYISQHLEKTKINKIATFFIL
                     IIGISTIVSGLIPADVNLIGHSILVWIGMLTIFPGLFIFAKNLKKARKWTYFCLLSLIV
                     ITILILLVFLFPLPAGLLQRLFYLVLFVWGTVLTYKLIK"
     gene            complement(19113..19331)
                     /locus_tag="EXW41_RS27565"
                     /old_locus_tag="EXW41_27960"
     CDS             complement(19113..19331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014893730.1"
                     /locus_tag="EXW41_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27960"
                     /product="hypothetical protein"
                     /protein_id="WP_088062864.1"
                     /transl_table=11
                     /translation="MKLYRKNLHFSALEQPLFLLALQLIAFVLIICIIYGILYNTTLKL
                     NMPKWTAHSVATVFSLGSAYRAFMNFI"
     misc_feature    19378..19396
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 26.61"
                     /tool="antismash"
     gene            19995..20591
                     /locus_tag="EXW41_RS27570"
                     /old_locus_tag="EXW41_27965"
     CDS             19995..20591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016100216.1"
                     /locus_tag="EXW41_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27965"
                     /product="ABC transporter permease"
                     /protein_id="WP_088062865.1"
                     /transl_table=11
                     /translation="MSYYYDDYWKDSKKKYHDCHKSSKSYDKCDKKHEEKPWVNVKVKC
                     CSDDNGYNLVRASAFRAVSTVNQNLPANTFVKVLFQNEQFDLANEYNPATSIFIPKTRG
                     VYSVIGTIAFIPNNLNVNYRARVEIRVNGNPAIAIDNDFFGPINFANVVAVSSIIQLNA
                     GDIVEVFAQSSVAGVISNVENSTHFEAARFPSPQV"
     gene            21572..21772
                     /locus_tag="EXW41_RS29795"
                     /old_locus_tag="EXW41_27970"
     CDS             21572..21772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002101837.1"
                     /locus_tag="EXW41_RS29795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW41_27970"
                     /product="hypothetical protein"
                     /protein_id="WP_252196074.1"
                     /transl_table=11
                     /translation="MGWNNNFGHSRDCNRFWDDLVFCGCGRRRRRNDFNDCHCKRDCDC
                     DECRRRRNHDRDRDHDDCRDW"
     misc_feature    22047..22060
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.26"
                     /tool="antismash"
     misc_feature    22430..22441
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.34"
                     /tool="antismash"
ORIGIN
        1 catcctcaca ggaattgtcg gtaagtacaa aagcgaatag catagccttt aaagaaattg
       61 caagtgctac tacaagatta aatttaggag cacattctca tgaatatgta gtgcaaaaat
      121 gtttaggaat tgttcaagac atggaaagta agatgaaaga aatgaaagga gctgcaaaac
      181 aagttaggaa tgcttcggaa gaaatggaac agcattctgg agaaggaaaa gatttgatta
      241 agcgaattgt gaatcaaatg aaaagaatcc aagatacagt tgaagatgta tcttctagta
      301 tgtatgcatt agaagcacga tctaaggaaa ttagtgaaat tcttactgta attacaacta
      361 tgtcaaatca aacaagtcta ttagctgtaa atgcttctac tgaagcctca tgtgctggag
      421 aggtggggaa aggattttca gttgttgcgg atgaggtacg tatattagcg gaaaaaaccg
      481 aggcatctgc aagggatata gctacactaa ttgatgaaac ccaagctgaa gcagatgagg
      541 ctgtaagatc catacagaag agttcaaagg aagtagaatc aggaataata cttgttcaaa
      601 gtggccgttc ttattttgaa aagatttcag aatcagcaca atctgttgcc agtcaaatta
      661 aagtggcttc gaataattca agtgacattt taaaagataa tcaaaatatt gttcagattg
      721 taaatgaatt atcacacatt gcaaatacat atgtgaatag cagtggtaat gtagagacaa
      781 gtatgaaaga gcaagaactg tatgtacaaa atattgcaga gttagcgaat tctttaaatt
      841 ggctctccca tgagttacag gagttaatag gggaattcaa aagtaagtag gataggagaa
      901 ggtgtaggta tgacctatac ctttatttat tcccacataa ggaatgaaag cttaggtata
      961 tatgtaaaat ggctaaacaa ataaattttt ttgcatattt tgttggaaat agagcatgat
     1021 attaccaaat tcaacggagg tgtttaaaaa atgcaaattc gcgaaaataa taattcaaac
     1081 gaaatcttaa tagcagctgc agcaagtgca attgaacaaa tgaaatatga aattgctcag
     1141 gagtttggtg ttacacttgg accggattca acagcaagag caaatggttc agtaggtgga
     1201 gaaattacaa aacgtttagt tcgtatggcg caagagcagt tatctggtca atataaaatt
     1261 cactaaagtt aaaggtatat cccatggaag ggatatacct ttttaatttg cctttaaaga
     1321 ggatagtgaa aatttttact gctagttaaa tttagacact gcaaatttgg ctgtgaaatt
     1381 catcttcttc atgtaagaag aatttactcc tgcttgaaat tgaacagaaa tattaccgtc
     1441 tttttgtgct ttgaatacgc gaccgtatgg tgaattcgca ttgtatgtgc caattacttg
     1501 atcatctgta tcaaagactg tataagaaat tgggaaccca gaattttgta caaagaccgt
     1561 aagttcttcc cctttattaa gattaaatga ttctttttga gaaacctcat aggaactcat
     1621 agagtaatat tttgtaactt cttgaatttc taaatttgta gttgctgcac tcgctatagg
     1681 tgcctctgct cctggtaagt tcatacctga tagtactgca attcctaatg cccctgctaa
     1741 aataactttt ttcataatgc tagttcctcc tttaatatat tgtgagattt gaaaacgaag
     1801 tgaaaatacc acctcttgaa accattatag ttacaacgag aatgattttc aatgagattt
     1861 gatatgtaat tctgcataca taagatgtcg atataaggta atctatccga agtttaaagt
     1921 attcttaaag aaggagagaa caacttttca aaactatgaa tgtgatggta gctggttttt
     1981 acatacgttg gttctataag tgaatatttt gttgtttttt tattgtgcat tcattgtatg
     2041 taaataaaca atcaattgtt gataaagttg tataatttgg aattattaaa caaaataaga
     2101 ggttatatgt tataataaag ctgcaataag gttcagcatc ctaatcttat tgtgtatatt
     2161 tagcctatgt atgtcgtttg tattaaaaat aagaagtctc tcaaaaagag gcttcttatt
     2221 ttttgtatgg agggggatta cagatgattg attattatca aattttttta tttactatgg
     2281 caggtattgc cttgtttttt tatatacaac atgctggaaa accgacgaaa agaaacaaat
     2341 ggaaattctt tgttgtagta tttttatttt tccttttgaa ttatttattt cttagattta
     2401 tataggtaaa tgtaagaggg gatacgtttt aaattttaaa atataaaaaa aggaaggtgt
     2461 aatccttcct ttcataatct agtttgtcaa tgcgaatatt taattaacta atgtcattgg
     2521 cgctgtgtaa attgtgtcaa cagatccgtc agcattcgta atttcaactt tataacggaa
     2581 tgtgcctgca tccccaatat cttcgccatt gcctgagaaa gtaactattt cttcatttgt
     2641 accagcgggt aacatagagt tccaattgaa ccaagttcca taatagcccc agccagtttc
     2701 atattgtttt tcgatagaaa ctttgtaatt cacactttca gttctatcat ttgtaacttt
     2761 tgcaatgaca ttttgtccaa atccgtattc cgtagcgtgt aattgaatcg tgaaattgtt
     2821 cactgtttcg ctagggccac aaatgtaacg acaatattcg ctcgctccat cagcatgagc
     2881 tttaggtgtt tctatattca ttgctgttaa actaccaaga gccaatgttc ccactaataa
     2941 tactttacca aattttcgca tataaaattc cccctgagta tgttttcaat ttgtttaata
     3001 gttgtcacat caagtagtta tatgacatta agcaaattga atgctctttt tccgtgatta
     3061 catttgctac cattcttcca tcttgtagta atttaatctg aacataaaat tccatggttt
     3121 taaatcctca atatgtatct taatgtacat tgaatagatc ctttaatata tcgatgatac
     3181 atttggttta tttacttgta tcatctcttt attaccgttt attggtaaaa agataatgtc
     3241 attatacata atattggaag ctactgacaa gagctaataa ttttgattta gccattaaca
     3301 ggaaagaaaa gtattaaatt agagcggtgt tcaaaaagaa gataaaaaca tttgaaatgt
     3361 gtgagaaatg atttgcagaa caattagagt acaagtaccg tgggagtttg taagtactgt
     3421 aacagaagag aatatgaagc agaagttaga gtctacacca ggtttattag taaatctatt
     3481 taaaacttgt aaaagaaacc attcaaaatc aaaagaaagc gaaatagaaa ggatatttag
     3541 ggaaatttaa aaggccttgt cattatagac agggcctttc aaaaagggac acaattgaca
     3601 actgaaggtg acttcatatt accatttttg gtattttaat tccaggtgtt cgtgttgaga
     3661 aataaaatga ttattttgta gagtgtgaga tgggggatac tgcttatcaa tttttcagga
     3721 cgggaaggca aaagcagaat tttttatttg ctttaaacaa aggataggag aaatattttt
     3781 gcttagcaaa gtgtgttaat catagatcaa agttatgtaa aaaaactgtt ttcaggatag
     3841 gtatccgttt tgttttaaga agagaatata ttttctcaac aggacaaatc gtaatcatct
     3901 ataagtacta tttataagga taataagaaa aatagaaatt aataataaag gagaatgcga
     3961 aatgaaaaca gtagtaactg atagagatct agctgaaatc cgtgaagaag acgtagatgt
     4021 tttaaaagta atggcacatc cggtacgatt acaaattgta aatgaattaa tgcatcataa
     4081 aatgtgtaat gttacgcaat taacggaaat attaagactc ccacaatcta ctgtttcaca
     4141 gcatctctca aaattaaggg gaaccgtact tcgtgcagaa agaaggggat tagagatgca
     4201 ttattatata gataatgcta aagcgcgtca gattgtagga atcttaggtt tttaggctaa
     4261 tagtatgtga aaagtttcct gtcatgaagc agggaacttt tcttttatga ttaacaaatt
     4321 gtcctcattt ataaagaaac ataaagctaa gaaagcgcga tgtctagatt gttttataac
     4381 gggtgcacat gtaaaattgc ataccatata ttcttgataa ttaaataaaa atgtaactat
     4441 aatgattaca ttgaatagat attgaataca tctattctta tagaataaca acggaggtga
     4501 ttgagaatgt atataaaaaa attgatccta gctggagcac ttggttttat aattcttgga
     4561 tgcgctaata tagcaggaga aaaagtaacg aaagctaatg cagcttcaat tgaaacagat
     4621 agggtaacaa tggagggacc aatagtcgag ttaggggaac atgattttta tattaagtcg
     4681 caaaagtaca atgaagactt tgataatccc ataagtgtag aagtagatta taagcgcaat
     4741 gttaaaatag ggattaagta aatttattgg gttgatgtga agaattttta gtttttagta
     4801 tctatatgac agaaactaaa gtagaaaaga tttaaatgaa atgaccataa gatagattaa
     4861 atgagagtaa catttagtta catttgtact acatcagatg aatataattg ccctaactct
     4921 tcagagtatg aaggtacttt aactagtaat gggaatcgta aaattcgaat taagagattt
     4981 aacttcttgg tattattata atttataaag atgtaagtat tatctttaaa ggaaggtaat
     5041 ttgaatccag aagcaggatg ctagataaga agttaataat tatcggttgc tcaaatgtag
     5101 agacaacgaa ttatgtttag ataaactaaa cttaaaatca ttttatataa atataacatt
     5161 ttaagaggtg gagtatgaaa aataagacaa gttttgtaag agttggagta accacaggtg
     5221 ttttgttatc cgcgattatg ccatttagcg gggcctatgc ggcaacagag gatttaaaag
     5281 tagaaacaaa agaagataca ttccgagcag gtaatctaac agcaccttct caaaagccgg
     5341 ctgaaaatgt agcgaaagat gcattaaaag gcaaaacaga acaggcatta tcatcacagc
     5401 aaattaatac ggaatcgaaa gttaattata atgtaacgca aagtcgtaaa tcttatgatg
     5461 gtacaacatt agtacgtctg cagcaaacat atgagggacg tgatgtatac ggatttcagc
     5521 taacagcaca tattaatgat gagggtgtac ttactagtgt tttaggggat agtgctcaga
     5581 agttacaaca acaggaagac ctaaatcaat ctatgacact atcgaaagag gatgcaaaaa
     5641 atcagatatt caatctatac gggaacgatc tcacatttat tgaggaacca gagattaaag
     5701 aagtagtgta tgtagatgaa aatacgaaaa aggctagaaa tgcatatcaa attaacttta
     5761 gtgcatctac acctgaatat gtatctggaa cagtattaat tgacgctttt aatggaaatc
     5821 tattaaaaga gattgttcaa aaattgggta tacaagtaga tagtagtatt gtccaatccg
     5881 cgacatcaaa taaatcacaa gatccctcaa aattaacagg cgcaggtaaa gatgatttag
     5941 gtattaatcg tacatttgga atttcacaac gaagtgatgg aacgtatatt cttgcagatt
     6001 attctcgtgg taagggaatt gaaacgtata ctgccaatta taaagactat aacaattata
     6061 aaagaaatgc gtgggggtat ctggatgatt tagttacaag taattctaca aattttacag
     6121 atcctaaagc cgttagtgca cattatttag caactaaagt atatgatttt tatcaagaaa
     6181 aatatggtcg tgacagcttt gataataatg gacaaaaagt aatttctgta gttcatggct
     6241 ggaacacaaa tggcacgaat aaaggcaatc ctaagcagtg gtttaatgca tttagtaatg
     6301 gggctatgct agtatacgga gatccaattg tcaaagcctt tgatgtcgca ggacatgagt
     6361 ttacacatgc ggttacaaga aatgagtctg ggcttgagta tgcaggagaa gctggtgcga
     6421 taaatgaggc tttatccgat attttaggtg tagctgtaga aaagtatgct aataatggga
     6481 attttaattg gacgatggga gaacaatcag gtcggatttt tagagatatg aaaaatccct
     6541 catcaatatc ttctagatat cctgaagatt ataaacacta taaccattta cctattgatg
     6601 ctgatcacga tcatggtggc gtgcatacaa actctagtat tattaataag gtagcttacc
     6661 tgatagctag cggtggtaat cataatggcg taaatgtcca aggtattgga gaagataaga
     6721 tgtttgatat cttctattat gtgaatacag atgaattaaa tatgacttct gactttaaag
     6781 aattaaaaga gggttgtatt cgtgtagcaa caaatttata tggtaaaaat tcatctgaag
     6841 tacaagctgt ccaacaagct tttaaagcag catatattta atacactaaa gagtgtatgg
     6901 atgataaaac ataattcttt aacgaaatag taattataat tatatagtat atataaaata
     6961 aaaaaacttt taggctccag gttccctata ctcaacaggg gatttgtagc ctaattttta
     7021 ttgattgcga gtccgataca taaaattaag aaaattcaat tcgtgttata tagtgatata
     7081 tagataaaac tgaaagttaa tattagaaaa tcaaaacgaa gggaagagaa attttgtttg
     7141 aaagttttcc atatattaaa cagcatgatt tacaagattg tggaccggca tgtcttgcaa
     7201 tgatatcaag acattatggt ctctctttat caatttcaaa aattcgtgaa gtttcaggaa
     7261 cagatttgaa gggggtgtat gaggaataag aataatattt ttaaaaatta aatagcataa
     7321 tatataattt agagggaata aaaatatagg ggagaacaat taagttatcc attaagggag
     7381 tttactacat gtatacttgt aatcaatgtg gaacaggaat gattatgcaa ctgcaagata
     7441 gatatagaga atattgtccg aaatgtgaaa tgcctaggcc gagtagctta atgtactata
     7501 atttatatga gctattagaa tatatggaag ttaatgaata cttgagtaag gaaagtatgc
     7561 tacataattt tctaaaatgg gagtttgagt taacggaagg gcgtatcttc aagttacatt
     7621 tagatgttga aagatacgat caaatcggtg atgagaattt tacaaaacaa ttagaaacat
     7681 atatgaaagg aatccgatta aaattaaatg ttaaatatga ggatgattat atctgggtta
     7741 aggttaatta gtaggactct acatataatg tgttctagtt tgaaaagata gtaagaagta
     7801 gagaggaggt caatagtaat ggaagattta caaaaggaag taataagatt tcgagatgag
     7861 aggaattggg gacaatttca taatgcaaag gatttagcca tttcattgaa tttagaagct
     7921 gcggaattgc ttgagacttt tcaatggaag tccagtcaag aagcaaagga gactaaaatg
     7981 caggaaatga aagaagaaat agctgatgta atgatttact tgcttctgct aagtgaccaa
     8041 ttaaatatag acttagaaga ggctgtacgc tctaagctga caaagaatgc tgaaaaatat
     8101 cctgtagaaa aagcatttgg aaaaaataaa aagtataatg aactctagaa gaggaattac
     8161 atttttcata tattatttaa tattaagatt atattttatc aacttggttt aacttgccag
     8221 atataattta ttacactata ttagtagaaa cttacaaagg aggaatctaa atgggaatta
     8281 gtattgaaaa actagataaa aaaatggaca atcgagagag tattaaagaa ataatagaat
     8341 tatggaattt aaacgcaata gaaactgcag attgtgaatt agaggaaagt cataaaaagg
     8401 ggattgaaga gcaattaatg gaattgattc aatcaagata tggtgcagtt tttgtagtaa
     8461 ctgatgaaat taatagacta attggttatg gaattggctc aataaagcaa gatttggtta
     8521 caaatatgtt atatggtcaa atagaggaag tttatgtgaa aacagattat aggaggaagc
     8581 aaattgcgca aaatttagtt gaaaaaatga gcaattggtt gaatcaagaa aatgtctctt
     8641 tgattcatgt ttatgttgac ttagctaata aattagcatt gaatttttgg gagaatacag
     8701 gatttgaaaa agaatttttt cttttatcta atagctaatc tatataatga aagtttaaat
     8761 aaaaataaag gttgaaagtc attatttaga aatatttaac agaatattca aattattaat
     8821 aggggaataa gtgcacttac accttatgat ttgggggcgg aattacataa attacttata
     8881 tttacataaa agtatataaa gttgaaaaaa tagattagag agaccttgtt tagaaaatat
     8941 ttacattttt atcaatagta aacaaataat tcagataagt gataaaaata catttttttg
     9001 tttatatgtg tttataaaat gttatttttt ggataaaaat acatccattt gtagaatttt
     9061 gatgttaaat gtaaaaaaaa gtagtttctt gagtagttta cattctaatt tcttgtgtat
     9121 aaacttcaac ttaattccat agaaaggagg gggagaagaa acatgaaaaa actagaggca
     9181 gggaaagtaa aggcatatgg atcatttatg gcagtaacat tagcgaagaa aaacaaacca
     9241 ggtgatggaa caagaacaaa aggaatccgt aaaggactat aaacgctatt aaattaaaaa
     9301 ataagggaga gaagaaacat gaaaaaatta gaagcaggga aagtaaaggc atatggatca
     9361 tttatggcag taacattagc gaagaaaaac aaaccaggtg atggaacaag aacaaaagga
     9421 atccgtaaag gactataaac gctattaaat taaaaaataa gggagagaag aaacatgaaa
     9481 aaattagaag cagggaaagt aaaggcatat ggatcattta tggcagtaac attagcgaag
     9541 aaaaacaaac caggtgatgg aacaaggaca aaaggaatcc gtaaaggact ataaacgtta
     9601 ttaaattaaa aaataaggga gagaagaaac atgaaaaaat tagaagcagg gaaagtaaag
     9661 gcatatggat catttatggc agtaacatta gcaaagaaaa acaaaccagg tgacggaaca
     9721 agaacaaaag gaattcgtaa aggactataa accttcttaa ataaagagga taggagggaa
     9781 gaaaaatgaa aaaattagaa gtaggaaaag taaagggata cggatcgttt atggcggtaa
     9841 ccttagctaa gacaaagaag ccaggtgatg gcactagagc taaaggagtc cgtaggcgtt
     9901 aaaaattgta aaatagaaaa cttgatttat gaactatcta agaagaatag tagaaatcta
     9961 gttctactat tcttcttaaa aaatgaagga ggagacaatt atgctgttaa aaaagaattc
    10021 taatactgtc acttctattg ctaatgagga agagacaatt gtgttgcata ttagtgaagg
    10081 tgaatactat ggcctagagg gtgctcataa agaaatttgg gataatttta atcagaattt
    10141 atttgaaaaa aaatcaattg tagaagaatt tttatctaaa ttcgataatt ctaaagagga
    10201 gatacaaaaa ttagtggatg aaagtgtaat ggatttaatt aattataaat taataatggt
    10261 tgttgataaa tatgaataac tctaaagaat attttgtcgc tttacataat ttagtaagag
    10321 gattgttaat tgaggattca tttgatgttg tgtttaataa agtctccatt cagttctttc
    10381 caatgtatga aagtgctaaa aggagaaaag caatgccgat aaatataaaa gaactgataa
    10441 catttagtaa atatttatat gaaatggatg aacaagacgc tttaatcgcc tcatgtgtat
    10501 ctatttcttt aacaaatcaa attgtcctat attcaaatgg aattgatgca aaattaaaaa
    10561 ttggatttaa aaaaatagat gaaaagttac attctcatgc ttgggttgag ttggagaatg
    10621 gagaagttat tgatcctcaa aatcatcttg ggaaactaca agtaatgcat atatttaaaa
    10681 tgagagatgg agttgaaagg tgggttacgg aaaatgagaa tgtggatagc tatgtgggga
    10741 gaaaataata ctataaaaaa acaatggaac aagaatttaa gaaattggtt aagttcaatg
    10801 aagataagta accaacttaa ttttgataga gagggatttt ttttaagtga agttgatttc
    10861 tcttataaag attctcataa aaagaccaat gagcaaattt cctttttagc taccccatta
    10921 attatgaatg gtgtactaag tgattcctta aagcattctt atgttgaaaa tttaacatca
    10981 aaagctaggg gaaatctgta taagggttta acatcaaata tagattatca attacaaaat
    11041 gctaatggtg atttcacaat tacatatgtt gatcgaaata tggataatct tgtaatagct
    11101 aatgacattt atgcgacgag gccaatctat tattataaac atccaaatga cgatttcttt
    11161 tgtgcatcaa atgatttaag aacgttgcta ttaaattatg aaattccttt tacagttaat
    11221 tacaacgcat gcttaaatta tccaactaca caatttgcaa ttagtgaagc ggaatatagc
    11281 aatgaaacat tttttaaagg tatttatcga ttaccaccag cctcaatttt acaatggaat
    11341 aaaaatgata aattaagtat tcgttcgtat tggggactaa ataatctact taataaagta
    11401 aaacatacga atattacgga ttatgtggat gagttcagac agacaatgct tgatgttgtt
    11461 caacttcgta tatcagataa aaagacaatt ttagatgtaa gtggaggctt agattcagga
    11521 aatattttag gagctgcaat tgccaatggc tcaagctcct ctatttttgg agttaatcta
    11581 tcttttgaat ctaacgatat gtcatttagt catgataaag aacttgtaac taagttatta
    11641 caagacttaa acattgaaca tgccattatt atgggggatg atattaacaa gattttaaat
    11701 gcagaaatag gaagagatcc gatgtggtat atagatggac ctgatccacg agggaatcct
    11761 ttgtatgatg aagttgtagc agcaatctct attgaagttg gtgccaatcg ttccatatct
    11821 ggcgatggtg gagattatgt agcgagtgga gaggaattag tcattgattc tttacttaga
    11881 cagaaaaagt ttaaagaagc agtatcaaaa ttatggaatt ggtctgataa aaaggtagga
    11941 ggattcttag ataaaacatt tacttatgga attgcaccat ttattccagg tttaaacgag
    12001 aggttatact ataagaccgt ttgggctgaa aaagtggaag cgaacatgcc attttttacc
    12061 acagaacata ttgaacgtga aaataaaggt aatcaaagag agtatgagca gtataaaaaa
    12121 agtaaggatt ttaaactttg gggacaccga tatcactatg attacttata tccaagggca
    12181 agatgtttag atacaactag ggtagcaaca gattatatgt acccgtttta tgataaaaaa
    12241 atgattgaac ttagtttttg cgttccacct gaagaacatt atgatttact agaagggcat
    12301 aaaaatggat attataaagg gtctaaacaa ttgatgagaa aagcgtttaa agatgtttta
    12361 ccagattatt tattgaatag aaaaataaaa acgacttatg cacacatggc tagaaaatgt
    12421 ttattaaatg aaaaacataa tattttacaa ttgttctcaa aagataaaaa gaattttgta
    12481 gcggaattag ggattattga taaggagaaa tatagagacc acttaattgc aatgttaata
    12541 agatctaatg atccaaataa tgatttaggg atgagttttc aatatttacg ttctgtttta
    12601 gagttagaaa tttggttaca agaagttgaa aagggaagag attatatttt agaaagaagt
    12661 aaaccagtgg atcctcgtaa tataggaaag tgtatttttt cttcagaatt aaaacaagca
    12721 acattctatt gaaagtagag gagagcaatg tttaattttt gtaaaaagca tatgctcaat
    12781 tttaaaaata atatgagcat agcttttttt ttagggaaaa taatatggaa atctagtccg
    12841 attttggtca tagttttgtt agttttactt agtgctgaag gtctaattgt tgccatacag
    12901 ttatttgcca caagggagat tctaaatgga attaaaaatg caaatcctag tgatacatac
    12961 gtgtatattt gggggattgt atattgttct acttttgtta taggaatttt ctctgtatca
    13021 attacgagtt ggattcaaaa gttactaggt gagaaatcta tgttaacaat taatacgaca
    13081 cttttagaag ctatagaaaa aatgccaggt atgcgttttt ttgaagaaat caaatatagg
    13141 gataaacttg agactctaag agacagtact agttggttac ctatgcaaat agttgaatca
    13201 acaggcagtg taataacagg aggaatttca ttaattagta tcatcatagt agttggtacg
    13261 ctttctcctc ttttagcagt gatattaatt gtaagcgcta ttccttttgt catatatgcc
    13321 aataaattta ctgcaatgga atgggtatat gaaaatgaat ttgcatctaa tcgaagaaag
    13381 atgtcctatt atagggataa tttattaatg aaaaatacgg tacaggaagt tagactgttt
    13441 aatttgggtg aattcttttt gaagcaatat aaagaaacgt ttgacgtagt attttcagca
    13501 tataaaaaaa ttcaaacaaa atctttaatt ccaattacat taactggttt attatctggg
    13561 ggagtatctg gaattggtta tttgtgggta acttataaaa taagtaacgc ttctttgaca
    13621 ataggagata tcgccttata tttaactgcc ttatttcaat taaatgtatt attaagaaat
    13681 gtttccaatg aatttgttga aacacttgag ctttggagaa tgggggggga ttttcatgat
    13741 tttgttaaat taaaaccgga tgtacaaatc tctccaaatt caaagtttgt agatttgtct
    13801 gaaatgaata ttgaatttaa aaatgtaagc tttagttatt caacaaataa agaacataaa
    13861 attctaagaa atcttagttt tagactgaat gcaaggcaaa gtacagccat tgtaggaatg
    13921 aatggtgaag ggaaaagtac aattgtaaaa ttactttgtc gattttatga tcccgatgaa
    13981 ggggagattt taattaataa tataaacata aaagaaatag aaattcagca tcttcgtaaa
    14041 catatttctg ccatctttca atcatttgga aaatatggtt tagcaataga tgagaacatt
    14101 ggaattggtg attatgaaag tattgaaaat aagaaacaaa ttcaagaaat agctaaacgc
    14161 gttggtatac acgagaaaat taatagttat tcagattcct ataaaacaat ggtaggaaat
    14221 gaatggaatg ggatagagtt ttcaggtgga caatggcaaa aaatagcact agctagggcc
    14281 ttttttagaa acgcttctac cctaataatg gatgaaccta cagccgcttt agatattaaa
    14341 tcagaagagc aattgtacaa tcaattttat ttattaacga ggcaaaagac agtattattg
    14401 atttcgcatc gttttagtac tgtaaaaatg gtggattcta ttattgtaat taaggatgga
    14461 gaggttattg aacaaggttc gcatgaagca ttaatggata agcaaggaga atatgcaaag
    14521 atgtatttaa tgcaagcatc tagtttttct ttagagggga ctgtgaaaaa tgaaaagtct
    14581 caataaggta tatcatactt ataaatttac aagggaaaca ttgacttctt taaaaatgct
    14641 atggaaagct gataaagtgg gatttaccta cattatgctc attaaaatac tggaatcaat
    14701 tattcagcca ttgcttattt ggttaagtac taaggtaatt gatgatttat caaaagaccc
    14761 tgcagcatta ttaaactcga atttcacgtt ttggataatc attacattta ttattctcac
    14821 aatcactgca gatttattta atcctttttt tgaagtgaaa aaaagattgt tggtagcgaa
    14881 actacagatg tatatcgatg tattaattat gaaaaaagct aatacattgg agagtcttga
    14941 gttttttgaa gataaagaac tttataataa aataaggtct tttagaaata atgagtattg
    15001 gattacaatg tggattgatt taatcatgaa atcatttgga ggcactgtaa agattatagc
    15061 tagtgttgca ttactatttt ctctcttacc gtggtatcca tttcttcttt tagtagtttc
    15121 tattccaaaa cttattaaag aggtaaattt aaatcaagca acatttgaag gtaggccaga
    15181 attaatggaa ttaaggagga gagctgaata ttatacgtca gttcctctat taccacaatt
    15241 agcgcaagag gtaaaattat ttcacttaac accttttttt aaagagaaat atgttaagac
    15301 ggtacaaaag ctgtcagcaa ctttaagtaa agatcaaaga aaattggctg ttcatagtct
    15361 gctttggggg cttatacaag cttgtgtaat ttcctttagc ataattttta ttatttatag
    15421 tgcgattaat aatgaagtat caattggaag tgtagtttta tttttaggta tgaccatcca
    15481 attatgtgaa ggcgttaatg agtattttgc attaattgct ataggggcga gggaaggaag
    15541 acatttaagg aacttactga attttattca atttcctaat cctaagagag taaattcatc
    15601 tttagtagag agtcaggaga aagattcggg tttctattta tcgcaagtag atttttcata
    15661 tcaaaattca gaagaaagtt ctcttagtat aaagaaattg cacataccac aagggaaaat
    15721 tactgcatta gttggcgaaa atggagcagg aaaaacgacg cttattaaat tattattaag
    15781 actatataat ccgagtcaag gttcgattta ctataataat aaaaacttaa acgattatga
    15841 ttcaactgaa tacaaaaaaa agtgtaccgc agttttacag gattttgtaa ggtacgaaat
    15901 gttactaagg gaaaacatag gccttggtga tgtgaaaaat attaataata ttcatgagat
    15961 tcaactagca agtgataaaa gcaatgtaaa ggaattgctt cctaccttga cagatgaata
    16021 tgacactcaa ttggggaaat tatttggtgg acaagaatta tcaggtggac aatggcaaag
    16081 aattgccatt ggaagagcat ttatgcgtga taaagaagca gaaatcttaa tatttgatga
    16141 accaacttca gcacttgatc catacgctga agatgaaata ataagagttt tatcaaacct
    16201 ggcggataat aagactgtta ttattgtaac gcataggtta agtactgcaa aattagcaaa
    16261 ccatatcatt tatttggata aaggacatgt aacagaacaa ggaacccatg aagaattaat
    16321 aattaaagat gggaagtatg cagagctgta ttctattcaa gctaagaaat acagctaata
    16381 ttttaatttg aagatttatt ttgttgaata taactccata cattgtttta tgcgagcttt
    16441 acttatgaat caatttacaa gtaaaagggg gctataaaga tgaaaaaaac gtataggata
    16501 ctattaatat taatgttttt aataggggtt tgtagtttag tagaggataa tgtaataaaa
    16561 gtttcagcag atacaaataa ggtaaataaa gcaaaatata ctgtgatggt ttatttggat
    16621 ggttctagtt tagagagtga ttttgagcta gcttctgaag atttaaaaga gatgctgaag
    16681 ataggctctt cagaagaagt taacatagtt attgaaacag gtggagcaaa aaaatggcat
    16741 acacctgcga ttaatccaga aaccaatcaa agatggataa ttcaaaaaga ttccctacaa
    16801 ttaattgagg atgttggact taagaatatg ggggaatcat ctacacttag cgattttatg
    16861 atttggggta tggaaaagta tccagcagaa aaatatgctg tgattttatg gggtcatgga
    16921 tcgggatctg tatatggata tggtcatgat gaacgatttg gattggatcc acttacattg
    16981 ccagaacttg aaaaaacgtt taaagacact tatgaaaaaa caagaaaaaa actagagatt
    17041 gtagcatttg atgcttgttt agttacaaat ctagaaactc ttagttatat aaatcagtat
    17101 gctaattata ttgttggttc agaagatatg gttccaggtc atggtttaaa ttatatatat
    17161 acatttgaaa agttattaaa taaaccaaat atgaatggag cagagttggg aagaatcata
    17221 gcagatggtt tttataagca agccatagaa aatgaagaag aagatgatat agctatgtct
    17281 gtaatagatt tgtctaaggt aaaacctatt acaaaagctt ttgatgatat agcaagatta
    17341 ttgaaagtag atgtattaaa tgatgataaa tttcaatcta tccttaccgc aagacgtaat
    17401 gtagaggagt acggaaaaat ggatggccca gaggattcag aaatggtaga cttgggggat
    17461 ttggcaaaac aaatgtattc tcaatatcca ttttattcaa gaagaattat gagtgcagtt
    17521 gatcaggctg tagtttataa tgtgaaaagc ccttggaaaa aagccactgg tatttgttta
    17581 tttttccctt taggtgacag agagagattt gatgagaaat tgaatcttta caaaaacaat
    17641 aatttctcca aagattatta tgatttcctt gaaatattta tagggaatct aaaaaataat
    17701 caattcatga acgtgagcaa cgaatcttta aatacaaata tagtaaaaaa aatttgatgt
    17761 gacatataca ggaatttaag taaatgaaaa gtcaaaaaag aatgtaataa aattaaatga
    17821 atagaaaaat agtagtatta tagtttttga aaataccttg atataaatat actttttttg
    17881 taatatatag gtatattgtt agtttatttg attccgttta ttcccacacc tgatgtgttg
    17941 tggttgagtt gtagaagtaa gttttgttct tactttaatt ttgaaagggc ttctttgagc
    18001 cgattagtgt aaatagctta ttttgctata cacaattaat cgacttgagg aagccctttt
    18061 tgttttgggt gaagcaagta tgaaaaagta tttctgtata caataacaga ttataagcat
    18121 gctctttgac aagaaaggta gatctctatg agtgaatgtc tccatgcaat aacatatgct
    18181 tgtccagtaa aaagttgatt caatttaaat aaaatcttta ttttattaat ttgtaggtta
    18241 atacagttcc ccaaacgaaa agaaccaagt aaaaaagtct ttgtagtaga cctgcaggta
    18301 aggggaaaag aaaaacaagt aagataagga ttgttattac tattaagctt agtaaacaga
    18361 aatatgtcca ttttctagct tttttaagat ttttagcaaa aataaatagt cctggaaata
    18421 tagtaagcat acctatccaa actagaatag aatgtccaat taggtttaca tctgcaggaa
    18481 ttaatcctga aactatagtg gagattccta ttataagtat aaaaaatgtt gctattttat
    18541 taatttttgt tttttctaga tgttgtgaaa tatatagtac tccaatacaa aatgttattc
    18601 cattaagaat aaagagtaaa ttcatccaaa agtgattagg ggagcatatt tcataaggcg
    18661 ctatttcgta ggtgaattct ccacaggttg ttacacctag gtcactcatt gcatgatgca
    18721 aatagttata aggtgctgta gaagtgaaaa taaagaaagg ttcaattaaa aagtataggc
    18781 aagttgcaat ccagctaaat aagccaatcc tatttgatat atacattaga ttcctccctt
    18841 gaaaaagtat agttccatta tagatgatta cattatcgaa agtgaaaaat tgcaatttga
    18901 gaatcgataa tcctgttcaa taatatagga ttttctggac aaatatgctt agcggaaaga
    18961 cgtataaaaa atggatggag caaaacttta aaaaatagtt atttgaaaat aaataaccgc
    19021 aaaaacgtca ggaaacccat taagttgcct gacgtttttg catggtaaag gatagattcc
    19081 tctacaaaag agagaaataa agaaaagtgt ttttaaatga aattcataaa agctcgatag
    19141 gcactaccga gggaaaatac cgttgctacc gaatgggcag tccatttagg catatttaat
    19201 tttaatgtag tgttgtataa gattccgtat atgatacaaa tgattaatac aaatgctatt
    19261 aattgaagtg ctaacaaaaa tagtggttgt tctaaagcac taaagtgaag gttttttcta
    19321 taaagtttca aatctgtaga tatttgacgg gcgataagtg aatgttaacc aaaacgctac
    19381 tgtataaaaa aagagaagcg cttaatcagg acgctcctct taatgccaat atacaataac
    19441 tattccatta taatgtataa gcgtaaaata tttaacaatt agctatgtgg taaaaatttc
    19501 attttgtgtt agtttaaatc ccaaaaagag cacttaataa agtgctctcg tgacgagatt
    19561 cattttgtaa tgactatttc aatttataga gaaaggaata cagaatatta tatgtgcttg
    19621 cagttaattg tgttcgtttt ttacaaaaaa agagcagtta gtaaaagcta actgctccaa
    19681 tcatggaata tggttcgaaa tgggttgtct atattatcga cagaatattg agttttattc
    19741 aggagtacct aaaggttttc tttttaactt aatccttatc ctacaaacaa aataatggct
    19801 aaaaacacag ataatgaaaa tgtcagaaag actgttatta tactcctgag catcgctttc
    19861 cagttgttta ctttagttgt gttctgccat tagggtgaga tttttaattc tattaaaaat
    19921 agtaacagct cgtccaaact tatctaatct atcttacata gtatgtagta gtaaatttaa
    19981 aggaggaatc tagtatgtct tattactacg atgattattg gaaggattcc aaaaagaaat
    20041 atcatgattg tcataaaagc agtaagagtt atgacaaatg tgataaaaaa catgaggaaa
    20101 agccttgggt taatgtaaaa gtgaaatgtt gttctgatga taacggatat aatcttgtaa
    20161 gagcatctgc ttttagagct gtgagtacag ttaatcagaa tttgccagca aatacatttg
    20221 ttaaagtttt attccaaaat gaacaatttg atttagcaaa tgaatataac cctgcaacat
    20281 ccatttttat accaaagaca agaggtgttt attctgttat tggaacaatt gcgttcattc
    20341 ccaataatct aaacgtaaac tatagagcgc gggttgaaat tcgagttaat ggaaatccgg
    20401 caattgcaat agataatgat ttttttggtc caataaactt tgctaatgtt gtagctgttt
    20461 catcgataat tcaattgaat gcaggggata tagttgaggt ttttgcacaa agtagcgtag
    20521 ctggagttat ttcaaatgta gaaaatagta cgcattttga agctgcaaga ttcccgtctc
    20581 cacaagtata agtagtatga aatctcgtca gtaattttat ctaagtaaag tccctaattt
    20641 atatttgacc tgcatacatg caggtctttt ttttcgatca aaaaagggat gaaaaaaggg
    20701 acgtttccaa ggatttttca aaacagaatc gatattacac tatatctata cagttctttg
    20761 aaagaaaagt agtgtgggga taacgtatct atgcgttgat aaacagttaa catagaactc
    20821 tttattaaaa ctttaccgga gaacgggcat ggacggtaag aatccgcaaa aaggacgaaa
    20881 aggcttatta catttatata ttcatctata gtccgtgaat gtcgtggatt ttgtgtgagc
    20941 ctgttgtatt tgctgggttg atgggtgaca taaacgtttg atatacaggt gctttaaata
    21001 tatatagggg agtgctcttt ttcgtttgcc tcttttgagg ggacaagcat atattgaaga
    21061 gtgtaggcca ggctcattcg cttgtatcta tcttatttca atactcataa gaaactcttt
    21121 atcatattaa aagcatctac gggtgcaagt gcgatctttt tattgaatga aatggatatt
    21181 tgaatgggag aatagttata aatgatagag cttaatccac tccatgaatg gtggaagatg
    21241 agtagttcca caaaatggta tcactacttc tgattgatgc caataattgc agtgtttctt
    21301 gaaataaatt gggtaatttt aacaattgtt gattctgttt tatttaagaa atagaatgcc
    21361 gaatgataag accaatatca attatcgttg acgctgccat gatctggttg gcgtcttgtt
    21421 tgttgttaag gaaagataag gggtgaggta gacttgcaag ttgaaatatt attagtctaa
    21481 aacaaaaaaa catagactag taaacaagct gttttcacta tttattcata gaatataaag
    21541 aattctattt ttagagaagg gaatcatatc tatgggatgg aataataatt ttggacattc
    21601 ccgagattgt aatagatttt gggatgatct agtattttgc ggatgcggtc gtagacgcag
    21661 aagaaacgat tttaacgact gtcattgtaa acgtgactgc gattgtgatg agtgtcgtcg
    21721 cagacgtaat catgaccgtg atcgtgatca tgatgattgt cgagattggt agagtctttt
    21781 aaaagagtgc atatctttat agcactcttt tttattgtgt tttttcatac ttaataattt
    21841 gaaaggcgca gtttcaatcg gatttaacgt ttaacaaaac aaacgaacac aacgaacaaa
    21901 aaaatacctg aggctattgc cccaggtaag cttgtacgat taataataat aattctgcta
    21961 ataatgtaat ctttaactgg caaggaaaat gcaggggatt caaggttaaa tcatttactt
    22021 taaagtagcg aatccgctgc ttttttattt tacaaaaaaa gaatctgcaa acatgcagat
    22081 tctcctgaca atgatttatg aagtaagacc cgaaaatata atacaatgct gtataaattt
    22141 aaacaaaata attcgtttat aagtaagtag attgaacgga ggggaaccgt atcgtatgaa
    22201 ttactcttct agaaatataa atgagaagga aatacgtcct ttggtgatag aggtattacg
    22261 tgattaccgg ctgttaaaag taaaattcca aaacatacag gagcggagtt actatttccg
    22321 gaacttagga aaagtacaaa tgatgaaatt agatatagaa gattaaaatg tgcatttgaa
    22381 gaagttttgg atgaggaaaa gcaacgggct ttacaagcga aatgcatgag aaaacgttat
    22441 taaaaaagaa tatagtaaat accctgattt taaagatggg aacaaataaa agtagcgaat
    22501 cagctgcgtt tttattttat aaaaaattaa ctttaaacat ttcttatagt tacgaatatt
    22561 tatgtaaata tgggaaacag atttgattct tggaatgagg ggatcgatgt ggatataaca
    22621 catattatgg cgagaatagt ggtgaatggg aaagatcttc cgtttacttc agttagaact
    22681 tctgcgtgga ttaatggacc tgcgaacgat ttaattgtta caactaagca aa
//
