LOCUS       NZ_CP036016            22497 bp    DNA     linear   CON 25-JUN-2024
DEFINITION  Bacillus toyonensis strain BPN45/4 plasmid p246.
ACCESSION   NZ_CP036016
VERSION     NZ_CP036016.1
KEYWORDS    RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 246340)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 246340)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 191.4x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739605.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:09:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,850
            CDSs (total)                      :: 5,697
            Genes (coding)                    :: 5,477
            CDSs (with protein)               :: 5,477
            Genes (RNA)                       :: 153
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 220
            CDSs (without protein)            :: 220
            Pseudo Genes (ambiguous residues) :: 0 of 220
            Pseudo Genes (frameshifted)       :: 93 of 220
            Pseudo Genes (incomplete)         :: 130 of 220
            Pseudo Genes (internal stop)      :: 65 of 220
            Pseudo Genes (multiple problems)  :: 52 of 220
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123278
            Orig. end                         :: 145775
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22497
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="deazapurine"
                     /region_number="2"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /tool="antismash"
     cand_cluster    1..22497
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22497
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12497](-)"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12497)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     misc_feature    44..62
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.65"
                     /tool="antismash"
     gene            266..2056
                     /locus_tag="EXW33_RS28330"
                     /old_locus_tag="EXW33_29090"
     CDS             266..2056
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016130611.1"
                     /locus_tag="EXW33_RS28330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29090"
                     /product="hybrid sensor histidine kinase/response regulator
                     transcription factor"
                     /protein_id="WP_000477307.1"
                     /transl_table=11
                     /translation="MFKTLKLWFWYDWALLCIRFIIWLSLISATIQQQDHLTVPLWIII
                     LWEVVSFSVPWICLMFSYRYYLFTEIILFGGVCFYLTLLFPLAYLAFLMPTFMIAANSV
                     HKSYRWSGPITIILFPLLIAIFSEVTDLWVIILQLSLAFAMGSFFRLLAINYRQSEIIR
                     NQKHVLEQYVSQVERITLLEERDRLSKDLHDTMGHSYTSIIMGMETLRVELKSKEGEHQ
                     LDSLLQLARNSMEEVRLYLHQLDLSQESLPLATTLQQLTEEFKKHAKVNVRTRIIGEEY
                     MVSKQSKMTLYRSLQESLTNAVRHGHSTEITVSLHFEPQQIRLDVQDNGCGVEEWKDGF
                     GLTAMKERVSQSQGRVIVYSKKGEGTLISCVLPKQVQLANEQIRLCIVDDHSFIRESLH
                     TILGGLEDLQVVGMAEDGERALELCERLKPDVVLMDLEMPNLDGIHATKMIKKKWPDIR
                     VLILSTFQNTERAKEIIRNGADGYVLKSIDSRELAESIRLVYRGGTMITHDLFHRMWEE
                     NEETGLFESRSVGIEYGLTKRELEILELLSQGSRYKTIASTLYLSNGTVRNYASNLYEK
                     LGVKNREEAVQKAKDIGLLS"
     gene            2698..3735
                     /locus_tag="EXW33_RS28335"
                     /old_locus_tag="EXW33_29095"
     CDS             2698..3735
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078444.1"
                     /locus_tag="EXW33_RS28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29095"
                     /product="serine hydrolase"
                     /protein_id="WP_033666113.1"
                     /transl_table=11
                     /translation="MNNSYNEKTHKSIKQLLKKFSSKSPGFTYISSFDSGVTYKGAVGL
                     ASIEKNLTITTKTVFNIASVSKQFTAFSILLLEQERKLSLDDSIVKFVPSIGAYAEPVT
                     LKHLIHHTGGLVDYMELAEAANIKYTDTLTVKESLEHLKSHQIARFPVGTKFEYSNTGY
                     FLLSLVVEKVSGKSLRQFAKERIFDPLHMKDTTIVDCYPTTISVANGYSRNEQGTYKIY
                     ESPWEHTGDGAVHTTVEDLVKWGENLTTGTVGGKNLVKRMSEIGPEISPTGDTIIDNED
                     YAFGLRLAEGFNYRHLEHSGSWAGYRSHFMRFPKEYLSVVVLSNYDGFDSKKYANKIAE
                     IVLEK"
     gene            complement(4128..5204)
                     /gene="xerS"
                     /locus_tag="EXW33_RS28340"
                     /old_locus_tag="EXW33_29100"
     CDS             complement(4128..5204)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128575.1"
                     /locus_tag="EXW33_RS28340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29100"
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_000386607.1"
                     /transl_table=11
                     /translation="MDYSKQRQKSVHRKKLYENLNEMPFYIEEFVEYKELHDASPSTLL
                     NYVYDFRVFFNWLLSEQIIELKPIKDISFSDLENLKKKDVENFMRFLKLQQNMQNSSVN
                     RKISALKSLFKYLTSLSENDDGECYFYRNVMAKIEIHKDKETLNARAKRMRSKIFHNDD
                     DQEFLNYVKYEHEKSLTKHQLFYFLRDKDRDVAILSLFLGSGIRVSELADLRMEDINLK
                     ERLIDVIRKGNKEDSVWITPIALNDIEKYMEIRDNKYAPGKELKNVFLSKYKHTAQPLS
                     VRAIQDIVEKYTKAYGKKMSPHKLRHTLANKLYMEEKDSLQVMQQLGHTSQDTALLYTQ
                     LGETTIKDSLGRIGKNKE"
     misc_feature    5243..5256
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.74"
                     /tool="antismash"
     misc_feature    6089..6103
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            complement(6306..7196)
                     /locus_tag="EXW33_RS28345"
                     /old_locus_tag="EXW33_29110"
     CDS             complement(6306..7196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017150390.1"
                     /locus_tag="EXW33_RS28345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29110"
                     /product="hypothetical protein"
                     /protein_id="WP_001223215.1"
                     /transl_table=11
                     /translation="MRITIQEYEVNEIDSGPYGITVGKDGALWFTEQKGNRISRINANG
                     EINSFPIPTANAGAMSIISDQTGDLWFTEYNSSKIGKMSMNGLFEEYVLPTTNAAPFGI
                     TEGPDGAIWFTEMNGGRIGRITKSGEIIEFELPNSKSFPSFITLGLDGALWFTQNQNNT
                     IGRITTKGEVTEYPIPTPNSGPVGITSGPDGAIWFVQIMGNKIGRITLKGEFKEFVIPT
                     PNARPHAIIPGKNGDLWFSEWGGNQIGRITVEGVITEYTIPTNNAEPHGITFCPDGDLW
                     FAEECNQIGRLTIIT"
     gene            complement(7373..8356)
                     /locus_tag="EXW33_RS28350"
                     /old_locus_tag="EXW33_29115"
     CDS             complement(7373..8356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016107154.1"
                     /locus_tag="EXW33_RS28350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29115"
                     /product="hypothetical protein"
                     /protein_id="WP_001004989.1"
                     /transl_table=11
                     /translation="MNENQQMIMNTNEVREYLEVSNFVVNNLIKQEELVPINKDTWRLD
                     GSFLFKREDVETIKKGRETEGITLYQASKKYGISTYQLEKWLGDGELAATIREHRNRKT
                     KFIREEELLQVIKQFDQENTLYTYSQKYNTVLFHKYIQSNTIARVISIPKRGDIMLIDE
                     FGSEFTLNEAIKSGFVPAYDLPDKPRSHHQRFVKFRLPKSDQLRSNSFQLIDLILQYVS
                     PRNLKVSEEEGFWYFDIRQSLIELPMGMQMEWIEYLTPYIIEGKLIKRVNNSIYLDSSS
                     VTKPVTLSSKEYQAINKIVEKTNTTIEEFIASAINQKIKDYQTSQN"
     gene            8713..9873
                     /locus_tag="EXW33_RS28355"
                     /old_locus_tag="EXW33_29120"
     CDS             8713..9873
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783621.1"
                     /locus_tag="EXW33_RS28355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29120"
                     /product="site-specific integrase"
                     /protein_id="WP_000667335.1"
                     /transl_table=11
                     /translation="MKFELITIHSGNSLENIEKQKQNFANIIALWNRDYINEAEFKKEN
                     NEREDSYTYEGFSDEEILYYYLNRQTHFDQEKRIKDASRTLYARDLSQFYFFIKQSTEF
                     LQQDVKDYVIGQVWRNLRKRHIRNYQKWLSQEAFSYQSKEKYKASTISRKLGVIRSYLK
                     WLYEIQYIREPLHIEILSTTVNKQHKPKRELSYEEVKHLLHYYKDNEINYALLSVLATT
                     GLRVAEVAHAKWEDLEYDAIRGRYYLTVDTKGDNERIVSINKDIFNRIVAFRIRRRLPV
                     NIGNKNGGTIFQTKNHTAYRENYLSQYISKIIKDTKLPFTENIRITPHFFRHFYVQYLY
                     DYKGLAPHVIAAAVGHKNDRTTKENYLKQRLTKDNDVGNLIGDDEF"
     gene            complement(10001..10588)
                     /gene="folE"
                     /locus_tag="EXW33_RS28360"
                     /old_locus_tag="EXW33_29125"
     CDS             complement(10001..10588)
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054143.1"
                     /locus_tag="EXW33_RS28360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29125"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_000054142.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 8.2e-77,
                     bitscore: 250.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKTIQSVEIDTDKIEVAVKMILEAIGEDINREGILETPKRVAK
                     MYKEVFQGLGQNPSEHLLKIFNENHEELVLVKEIPFYSMCEHHLVPFFGIAHIGYIPNN
                     GKVTGLSKLARALETICKRPQLQERITNELANVIFETLEPKGVIVVIEAEHMCMTMRGV
                     KKPGSMTITSSYKGIFKDNSTLRSETLNLIER"
     gene            complement(10632..11348)
                     /gene="queE"
                     /locus_tag="EXW33_RS28365"
                     /old_locus_tag="EXW33_29130"
     CDS             complement(10632..11348)
                     /EC_number="4.3.99.3"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="queE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036298.1"
                     /locus_tag="EXW33_RS28365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29130"
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_000086945.1"
                     /sec_met_domain="QueE (E-value: 2e-58, bitscore: 191.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.9e-12, bitscore: 39.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.4e-13, bitscore: 44.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRIPVLEIFGPTIQGEGMVIGQKTMFIRTAGCDYSCSWCDSAFT
                     WDGSAKEQVRQMAPEEIWNELVGIGGENFSHVTISGGNPVLLKNIQFLLTVLKENGIRT
                     AIETQGSKWQEWLLQIEEVTISPKPPSSKMKTDFTMLDSVIHKLERKNFSLKVVVFEDY
                     DFEYAVKVHKRYPQVPFFLQVGNDDTKTVDDAALIKNLLQKYERLIEKVVQCKEMNDAK
                     VLPQLHALVWGNKRGV"
     gene            complement(11341..11832)
                     /gene="queD"
                     /locus_tag="EXW33_RS28370"
                     /old_locus_tag="EXW33_29135"
     CDS             complement(11341..11832)
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368418.1"
                     /locus_tag="EXW33_RS28370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29135"
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="WP_000426938.1"
                     /sec_met_domain="PTPS (E-value: 1.9e-37, bitscore: 121.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFFGFHIVENLQKMDKDIQLEQLKYHNKRVMVSKEFTFDAAHH
                     LHCYEGKCKNLHGHTYKVVFGISGYVNDIGLVIDFGDIKEIWKNEIEIYLDHRYLNETL
                     PVMNTTAENMVVWIYEKMVEALIKGNRAEEYKGARVEFVRLFETPTSYAEVRREWILDE
                     "
     gene            complement(11832..12497)
                     /gene="queC"
                     /locus_tag="EXW33_RS28375"
                     /old_locus_tag="EXW33_29140"
     CDS             complement(11832..12497)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287172.1"
                     /locus_tag="EXW33_RS28375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29140"
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_000287174.1"
                     /sec_met_domain="QueC (E-value: 3.2e-86, bitscore: 282.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSNDKAIVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLE
                     IDCAAKIANELRIKHKVIDMSLLNQLAPNALTRIDMEITHEEGELPSTFVDGRNLLFLS
                     FAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWID
                     KADTWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKVGLDTYLQERKGENE"
     gene            complement(12510..13298)
                     /locus_tag="EXW33_RS28380"
                     /old_locus_tag="EXW33_29145"
     CDS             complement(12510..13298)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003203745.1"
                     /locus_tag="EXW33_RS28380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29145"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_000621952.1"
                     /transl_table=11
                     /translation="MIRYLKMLKAILKINLSNIMMYRVNFFLNILDSVVWFIVTLVFFN
                     SIFDSFGNINGWNTNDIYLLIGTSELIKSLMFTLFINNLPYIPSLVNQGSLDQILFKPI
                     NSQFLVSLRKLDLGNLGNCLPAVLLISYALLQKGESVSIVNGFSFLGLLFLGIILSYSL
                     WFILMTLSIWLTKVEGMHELFLGTMTLLRYPSSLYKGISRFVFLFVFPIVIVSNIPTYA
                     LIGRLELNDVFVLLGYSIGFFIISIYFWKFALRYYNSASS"
     gene            complement(13301..14092)
                     /locus_tag="EXW33_RS28385"
                     /old_locus_tag="EXW33_29150"
     CDS             complement(13301..14092)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018782253.1"
                     /locus_tag="EXW33_RS28385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29150"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_000760371.1"
                     /transl_table=11
                     /translation="MKKYLKPMMLSFQAVFQYRMNVVLYMIFGLIPLVALILLWHSLFE
                     TQSNIQGYTLEMMITYVIIAKLIELLLIPEMHWSINEEIQSGELSKYLIKPFSYFGYWF
                     SHNLGNKIIHLLMSVIPIIPIIFLNRDYFLLPTLKYTFLFILSIVGASILYYMVYYLIS
                     LFSFYFVEISSFFFTVDIVLELLSGSLIPLEFLPAPLNTITRFLPFSYLIHFPVNVYLG
                     KLSGTEIVNGLISQVIWSLVFYVLIRILWKKGLNKYESVGA"
     gene            complement(14089..15087)
                     /locus_tag="EXW33_RS28390"
                     /old_locus_tag="EXW33_29155"
     CDS             complement(14089..15087)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006097705.1"
                     /locus_tag="EXW33_RS28390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29155"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_000351265.1"
                     /transl_table=11
                     /translation="MDIIEIENVSKTFERVKIEEGLINSFKSLFKREKVTVTALSDVSF
                     KIKEGKIIGLIGANGAGKSTLMKAMVGLIKPTSGRILINGFNPHDKKKDFLKSIGVVLG
                     QKNQLWWDLSPYETFLLHKEIYELSDTEFRKNVDELAKNLGVSEILKSPVRNLSLGERM
                     KCELIASILHSPKILFLDEPTIGLDFLAQKNIRNFLKNYCKERNTTVVITSHYFPDIYE
                     LCEELIILKNGEVVFNNNFKKIKEEIKSYKYIYLSFENEINSQDLKKYGEVKESDKFSV
                     TIKVQDKLVNETISSILKEFNVIDYNLTEMSSQDLIEDIYSMESTGVKITV"
     gene            complement(15105..15761)
                     /locus_tag="EXW33_RS28395"
                     /old_locus_tag="EXW33_29160"
     CDS             complement(15105..15761)
                     /EC_number="3.5.1.-"
                     /GO_function="GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002090560.1"
                     /locus_tag="EXW33_RS28395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29160"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_000652093.1"
                     /sec_met_domain="PIG-L (E-value: 1.6e-26, bitscore: 87.4,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDIVKKHLVIAPHHDDEVIGCGGTIAQAISKGEHIKVIIITKGD
                     LSGGVGDLNEIISNRENECINACNTLGIEKGDIKFLKKPDRSLVYSLDFVEEIIHEISK
                     YKPNFIYFPHDMESDRDHRIVNEVVSEAIFLCQSGFLKENFAPMCLQYEVWTPMKNYQV
                     VKDITRFIELKKASIKKYESQLKTLNLVDGVLGLNAYRGMQAGVQFAEVFRVVSK"
     gene            complement(15887..16687)
                     /locus_tag="EXW33_RS28400"
                     /old_locus_tag="EXW33_29165"
     CDS             complement(15887..16687)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002205032.1"
                     /locus_tag="EXW33_RS28400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29165"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_001187390.1"
                     /transl_table=11
                     /translation="MQQQYDEISELYDIIIPEPDGIFDFYSGLVKANDEVLDLGCGTGR
                     LSFILAEKGANVTSVDISAGMIEKASKKLDEMPNIKDKIEFKVSSATDFKSERKFDFIF
                     MSGGVFEYLLTSSQQKLALRNIKLLLKEDGIFVFDIITPPTILPYSKRVSDGGNSPIKG
                     ENFKKYKIKSWDVVKADHYKQIVETTCYFEVYDITDNFLSEKNFRFLAKYTLPSEMQYL
                     LEIEGFSIKNFYGDYNKNPFGRNSEFMVYECRKQGGNFNDIQCE"
     gene            complement(16699..17478)
                     /locus_tag="EXW33_RS28405"
                     /old_locus_tag="EXW33_29170"
     CDS             complement(16699..17478)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128555.1"
                     /locus_tag="EXW33_RS28405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29170"
                     /product="glycosyltransferase"
                     /protein_id="WP_000933535.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-17,
                     bitscore: 57.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNLSIVIPAYNDVRLEKCLKSIDENVEVVVVLNGATEEVKKIAY
                     SSNAVIGELPTPNLAKAYNYGIEISSKDNVLIMDSDCVFMPGTINKLFKLLDAGPLAKG
                     RVMFSFNSKIGKIIARARHIHTCKKNAYSPPLAFNKAILAKVNGYYFDENLSWTEDYDF
                     DIRVKSANLKILYDDKARIIHPELSIKQDLKSSFNYGVGHARGVLHKKDGYYEPKNKTK
                     SIINSYKYIKKKYGYLTAFYLIFWQLAFYRGYKKEMH"
     gene            complement(17444..18202)
                     /locus_tag="EXW33_RS28410"
                     /old_locus_tag="EXW33_29175"
     CDS             complement(17444..18202)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018782256.1"
                     /locus_tag="EXW33_RS28410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29175"
                     /product="DUF5591 domain-containing protein"
                     /protein_id="WP_001246017.1"
                     /transl_table=11
                     /translation="MRNRNYSNLQDEKVKDLVLNKKSYPYYPEYILLDLIKEETVFKRG
                     ACSKYIHHEEFNTWQEYFCGDYYEKPQGKRIAFLQVCSWAKPYDFSYIGKKIREVTNKY
                     PMVHPIILSNAGIIPYEYQMNPTFCAYDWMDDIEDPVIYEELMKEYRDKLIQRIRSYLE
                     SNSYDVVVQYGIPVKKYSMAPVIKDICKDLGITFLLTPDIETYRNNKDKLVELKDSGEF
                     YCLDEVLSSMDNCLNKVSRYVESINCNTGL"
     gene            complement(18216..19883)
                     /locus_tag="EXW33_RS28415"
                     /old_locus_tag="EXW33_29180"
     CDS             complement(18216..19883)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289405.1"
                     /locus_tag="EXW33_RS28415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29180"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000289407.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 3.3e-41,
                     bitscore: 135.7, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVLGVNGWDFDVHDASACLFYNGKLIAAAEEERFIRQKKALDKI
                     PYNSIAYCLKEAEITPNEVDHIVMGWDVEQLYFEKYSKKLNKDECLEKIFPKRIFKRDK
                     DPQIHMCSHHLAHASGAFFSSGFNEATIIVIDGSGEEESITIAKGKGNIIEVLEKYPLE
                     HSLGIFYEALTVFSGLGRHNEGKLMGLSSYGEEIFEFPEILENPLKPNRNTVSMNGKYF
                     SVLKDWIKVINSITKIAPNYIKYEYNPIDSILLMNSSVMEYKNIAASGQAALERAIVKL
                     VKKAVNLTGINNLCLSGGVALNCIANRIIADLPEVNSLYIQPGASDSGVSIGAATWFLA
                     ENGIAPIFTVDHVYSGPEFTDSSILNILKKYNLSYIELGSNKYDRCSELLMQNKIIGRF
                     SGKMEFGPRALGNRSIIANPQNKDMLNKVNTIKKREQWRPLAPSIIDENASVVLEERIN
                     NPYMLLNSTVKKEVHHLVPAIVHVDGSTRAQVVTRDMNSDYYETIYNFYQKTGIPAVMN
                     TSFNVGKEPIICNPSDAIRSFYGSEMDALLLGSFLILK"
     gene            complement(19904..20938)
                     /locus_tag="EXW33_RS28420"
                     /old_locus_tag="EXW33_29185"
     CDS             complement(19904..20938)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662192.1"
                     /locus_tag="EXW33_RS28420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29185"
                     /product="bis-aminopropyl spermidine synthase family
                     protein"
                     /protein_id="WP_000662191.1"
                     /transl_table=11
                     /translation="MKENKIILLYERFIELDYEEELDKVPKLKNRGVLLHFWKKWYEIS
                     EKQFEFIIWKAINTVDTLDDLVKITGTLSLALRLLKVLKERNLVEIIENKIRFSQDLTS
                     SILYEPASLPNTGYENKINKKKYAQFKATWDSSLRRAEIINQELSSNKNIFFCGDDDYT
                     SLALKQYKNREISVGDIDEELIEYFKRTDNDIKFYNFDVRNEVIEDLRNKYDAIHCDPI
                     DDGRGLDLWLNRANELLKGQKGDLIFLNISVKRLGNRAVYLQNFLTSLGFYLKEIIHDL
                     SSYKVAEEPYIDEELIKKDLDGIGFSKDTFQNLYIQTDMLVFVRLIDKPTLFPQEYYEI
                     RRKI"
     misc_feature    21231..21245
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.12"
                     /tool="antismash"
     misc_feature    21384..21398
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.98"
                     /tool="antismash"
     gene            21578..22321
                     /locus_tag="EXW33_RS28425"
                     /old_locus_tag="EXW33_29190"
     CDS             21578..22321
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002105787.1"
                     /locus_tag="EXW33_RS28425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_29190"
                     /product="site-specific integrase"
                     /protein_id="WP_002105787.1"
                     /transl_table=11
                     /translation="MKDLPPTSDKKKYLFREIITYDVQGNPITEVFKYTVVNTGILNKV
                     CNKTPLSNIGAESGDIYKISPHQFRHTVATEMIDAGVDIYAVKNFLGHSSVTMTENYIK
                     VYQQRLKKEFKEKLLKSDATAIKENLPGQEEIFGDNKWVKNKIIAIFDQGDGCCEHPYK
                     MPSCPHQVACKTCIKKKILPRHKNAVVDTIDAFTTHLNQAKQIGLEEKIEEFDKVVQFY
                     QNALEVIKKGETFDAAKHFYTGGVH"
ORIGIN
        1 cagaaaattt ttgtcggaat aatgagtctt atatgtgctg ttttactgta tgtaatgcca
       61 atagtatgta tcgttacccc cttacttttt caatatttta atatatactt attgggcatt
      121 gctgtgaatt catgggagac agcaattttt gtcatgattg ttggtttcat tctcatctgg
      181 atacataatc ttattggaaa cgacttagtt cgaattattg gaatgtacac gcgtttcatg
      241 tttaaagcta taaaggagtg ataatttgtt taagacttta aaactatggt tttggtatga
      301 ttgggcctta ctttgtatac gctttattat ttggctatca ttgatatcag cgactatcca
      361 acaacaagat catttgacag taccactttg gatcataatc ctttgggaag tcgtttcatt
      421 ttcagtacct tggatttgtt taatgttcag ttatcgctat tatttattta ctgaaataat
      481 attatttggc ggagtttgtt tctatttaac tttattattt ccgttagcgt atcttgcttt
      541 tttaatgcca acttttatga ttgcggcaaa tagcgttcat aaatcttacc gctggtcggg
      601 tcctatcaca attattttgt tcccgttgct cattgcgata ttttccgaag tgacagattt
      661 atgggtaatc atcctacaac tcagtttagc ttttgctatg ggctctttct ttcgtttact
      721 ggctattaat taccgtcaaa gtgaaattat tcggaaccag aaacatgtat tggaacaata
      781 cgtatcccaa gttgagcgga ttacattact ggaggaacgt gataggctct caaaagactt
      841 acacgatacg atggggcatt cctatacttc aattattatg gggatggaaa cattgcgtgt
      901 ggaattaaag tctaaagaag gagagcatca gctagattca ttattacaat tggcccgtaa
      961 cagtatggaa gaagtaagac tgtatttaca ccaattagat ttatcacaag agtcgcttcc
     1021 cttagctacc acactacaac aattgacaga ggaatttaag aaacatgcaa aagtaaatgt
     1081 acgtactcga ataatagggg aagagtatat ggtctccaaa caatcaaaaa tgacactata
     1141 tcggagcttg caggaatcac taacaaatgc tgttcgccat gggcattcca cagaaatcac
     1201 tgtgtcactt cattttgaac cacaacagat aagattggat gtacaggata atggctgtgg
     1261 ggtagaagag tggaaggatg gctttggatt aactgcaatg aaagagcgtg taagtcagtc
     1321 acaaggaaga gtcattgttt attccaaaaa aggggaaggg acattaattt catgtgtttt
     1381 accgaaacaa gtacaactgg ctaacgaaca aattcgcctg tgtattgtcg atgatcattc
     1441 ttttatccga gaaagtcttc atacaatttt gggtggactg gaggatttac aagtagtggg
     1501 aatggctgaa gatggagaac gggctttgga attgtgcgag agactaaaac cagatgtagt
     1561 attaatggat ttagagatgc caaatctgga tgggattcat gcaactaaaa tgattaagaa
     1621 aaaatggccg gacattcgtg tactcattct gtcaaccttc caaaatacag aaagggcaaa
     1681 agaaatcata cgaaatggtg cggatggata tgtattgaaa tccatagatt cgcgtgaact
     1741 agctgaatca attcgtctag tctatcgagg aggcacgatg attactcatg acttgttcca
     1801 taggatgtgg gaagaaaatg aagaaacagg attatttgaa tcacgatcag ttggaataga
     1861 gtatggatta acgaaacgag aattagagat tttggaacta ttatcacaag gaagccgtta
     1921 taaaacaata gcttcgacac tttacttatc aaacggaacg gtaagaaatt acgcctccaa
     1981 tctctatgag aagctaggag ttaaaaatcg agaagaagcc gtacaaaagg caaaagatat
     2041 aggattactt tcttgactct ctcacttgaa ctagttagct gaagttaatg ggggacttac
     2101 agatgatgca ggacatcact acccaatcct acatttgaaa ctacaatgaa aaataaagat
     2161 ttggaacgcc tttgcttttt tgtgaacaaa gttgtttaaa aaggttattt ggattctcat
     2221 atcgaaaaag taaaacacta tagacgaaga ctataaaatt tgtagactat aactaaattt
     2281 gaaacaaggt ttaaggtaga tgaatgtttt attcaaacct atctttacag aggactggta
     2341 aatagttttc atattcgtta gtacatcggt cctaaatctg aaagtaaaat aggtatttgg
     2401 gtcaataaca tctttgattt agatgttatt gacccaattt agaaaatatc tattaagttg
     2461 ccatgagtaa ttttagaatt gaaagaggga ctttcgtaaa ttcggggata ataatactca
     2521 ctaaattaaa gttctctata aagagaagaa tttagaaact aaagaaatta gtgtgatggt
     2581 gcatgattgt agttaaatat aaaatatgtc gttttgagtt gaagtaagat gtgtaattgg
     2641 aaaagataac aggttaatat atttctaatc atttaaaggg aagggtatgt gattgaggtg
     2701 aataattcat ataatgaaaa gacgcataaa tcgattaaac aattattaaa aaagttttca
     2761 tcaaaatctc ctggatttac atatatttct agttttgata gcggcgtaac ttataaaggt
     2821 gcagttggct tagcttctat agagaaaaat ctaaccatta ctaccaaaac cgtttttaat
     2881 atagcctcag tttctaaaca attcacagca ttttctatat tactcttaga acaagagagg
     2941 aaattgagtt tagatgattc aattgtaaaa tttgtccctt ctataggtgc atatgctgaa
     3001 cctgtaacat tgaaacatct aattcatcac acgggtggac tagttgatta tatggaattg
     3061 gctgaagcag caaatattaa atatacggac acattaactg taaaagaatc gctagaacac
     3121 cttaaaagtc atcaaattgc aaggttcccg gttggaacaa aatttgagta tagcaataca
     3181 ggatattttt tattgtcact agtggtagag aaggtaagtg gcaagtcttt acgtcagttt
     3241 gcaaaggaac gtatttttga tcctttacac atgaaagaca caacaattgt ggattgctac
     3301 ccaactacta tatcagttgc taatggatat tcgaggaatg agcaaggaac atataaaatc
     3361 tatgagagcc cttgggaaca tacaggggat ggggcagttc atacaacagt tgaagacctg
     3421 gtaaaatggg gagaaaattt aaccacaggt accgttggtg gaaaaaatct tgttaaaaga
     3481 atgagcgaaa taggtccgga aatttctcca actggggata caattattga caatgaagat
     3541 tatgcttttg ggctaagact tgctgaaggt tttaactatc ggcacttgga acattcagga
     3601 agttgggcgg gttatcgttc acactttatg cggtttccaa aagaatattt gtccgttgta
     3661 gtcctaagta attatgatgg atttgactct aaaaaatatg ctaataaaat agcagaaatt
     3721 gttttagaaa agtaaaaaat agagggtaga agtcagtatt tagatttgct ttatcccacc
     3781 ttgttttagg tgtaattaat tttgagaacg gaaggcaagc ataaatttat gcctgccttt
     3841 ttgggtatta aaatgaattt aaatgttaat atccattttc atgtctccct acattgtaca
     3901 agataagaga agtggggaac tcctatctat tcaagtgtta tttatattat gatttaattt
     3961 aaacaacaaa tatgagaatc tagatttctc tgtttttctc atctctctaa caagggaatt
     4021 cttatatact aattaaagta gaatttaaac tatgtatttt ttatataata aaatcaaaga
     4081 tgatgagaaa agaataaaag ttcagcaata gatgtgtcgc tgaactttta ttctttattt
     4141 tttccaattc gccccaaact atctttgata gttgtttctc caagttgagt gtataacaag
     4201 gctgtatctt gactggtatg cccaagttgt tgcatgactt gtaacgagtc tttttcctcc
     4261 atgtatagct tattcgccag tgtgtgtctt aatttatgag gagacatttt tttgccatag
     4321 gccttcgtat atttttctac tatatcctgg atagctctaa ccgaaagagg ctgtgcagta
     4381 tgtttatact tcgataaaaa cacatttttt aattctttcc ctggagcgta tttgttatct
     4441 ctaatttcca tatacttttc aatatcattc aatgcaattg gggtaatcca tactgagtct
     4501 tctttatttc ctttgcgaat tacatcaatt agtctttctt ttaggtttat atcctccata
     4561 cgaagatcgg ctaattcact tacacgaata ccactaccaa gaaagaggga gaggatagct
     4621 acatcacgat ctttatctct taggaaatag aataactgat gttttgttaa agatttttca
     4681 tgttcatact taacataatt caaaaattct tgatcgtcat cattatgaaa tatcttagat
     4741 ctcatacgtt ttgcacgagc atttaatgtt tctttatctt tatgtatttc tattttagcc
     4801 attacatttc tataaaaata acattctcca tcatcatttt ctgataggga agtaaggtac
     4861 ttaaataaag actttaaggc tgaaattttt ctgttaacag aggaattctg catgttttgt
     4921 tgtagtttta aaaatctcat aaaattttca acatcttttt tctttaaatt ttccaaatca
     4981 gagaaggata tgtctttaat gggtttcaat tcaataattt gttcagataa taaccaatta
     5041 aagaagactc taaaatcata tacataattc agtagggtgg agggagaggc atcatgcaat
     5101 tctttgtact ccacaaattc ttctatgtaa aagggcattt catttagatt ttcgtataat
     5161 ttcttacgat gtacggattt ttgacgttgc ttgctgtaat ccataaaaat cacctcatat
     5221 atactataac agaaaaaata cgcgaacaca agttcgcgta aaattcaatt tttacacata
     5281 cttgtttaca taattaaatt atggttacta gaatgtaccc gaaattgaat aaggatagtg
     5341 taatcattct attgaaaatt atagataacc aattgataaa taaaaattac atgtgaatgt
     5401 agataaaata aaggattctt catacaaaaa tcaatatgtg gaaactgttt aaaagtcgtt
     5461 atcaaatatg aattgattat tctaatcaag attatgagga ttttattaga tcaacataag
     5521 aaaagatttt ataaattaaa atgtaatata ctataaacat tattaacgag taactcagta
     5581 tttaataatt tctatatgaa gtatgaattt tacaggtaca tatcaatacg ctaagattaa
     5641 tacaattgag ctcaaacccc ctaaatactg tgttagagtt ttatttaacc ctattattgt
     5701 tcgtaaaatc aggatttcgt gcgaagtttt gaagtgttta tttttttgcc tctttataaa
     5761 tgcatcattc acttcccttt cgtcagtatg aatatcttct agtttcagat acattcagct
     5821 atacacatta atatcgatta catggttgtt tctaagacat agccagtata taacatttta
     5881 ataccaaaca gttaacttta gccccttaag actaaataag ttttgttttt cacaaaactt
     5941 atttgttgtg atgtcgaaat agaattttcc ctttaattct ttattattgt acttggttta
     6001 gttgagcatt ccactaaatt tgattttaat acagatttca aaatataact tctaaatttc
     6061 tctttccgcc tcaatgatat aagtattctt ttcattttga gatttattcc actcattttt
     6121 tacaaatacc tataagatag attgactaat ttaaaattta tagatatagc aacacacatc
     6181 catcaactta agaattttat aaaaccccaa aacgaaaaag ttatacattt tcaactggag
     6241 atgtcaattt tctcgttttg ggatatttac ttttctgagc ttaatagcga tgggtgatat
     6301 ccttattacg tgatgattgt taaacgtcca atttgattgc actcttcagc gaaccaaaga
     6361 tcgccatctg gacaaaacgt gataccatgt ggctctgcat tatttgtagg tatcgtatat
     6421 tccgtaataa ctccttcaac tgtaattcgg ccgatttggt tacctcccca ttccgagaac
     6481 cacagatctc cgttcttccc aggtattatg gcatgaggac gagcgttcgg cgtgggtata
     6541 acaaattctt tgaactcacc ttttaacgta attctaccaa ttttattacc catgatttgt
     6601 acaaaccata ttgctccatc tgggccgctc gtaattccaa ctggcccgga gttaggtgtt
     6661 gggattggat attctgttac ctcaccttta gtggttattc tcccaatcgt attgttctga
     6721 ttctgtgtaa accataatgc tccgtctaat cccaaagtaa taaatgaagg aaatgatttg
     6781 gaattaggca attcaaactc gatgatttca cctgactttg ttattcttcc gattctacca
     6841 ccattcattt ctgtaaacca tattgctcca tcaggacctt ccgttatgcc aaaaggtgca
     6901 gcgttcgttg tggggagtac atattcttca aaaagaccgt tcatcgacat tttaccgatt
     6961 ttgcttgagt tatattccgt aaaccataag tcaccggtct gatccgagat aatggacata
     7021 gctcctgcat ttgctgttgg aattggaaaa gaatttattt caccattagc atttattcta
     7081 ctaattcgat tccctttctg ttccgtaaac cacaatgctc cgtcttttcc tactgttatt
     7141 ccatatggtc ctgaatctat ttcattgact tcatattctt gtatcgtgat tcgcatatca
     7201 taccctccta ttgaaaattt tgagtgttgt ctatgattat atcacttgta atcatcaggt
     7261 agctgtggga gtaatcttag ttgtataaat gatagtaaaa agaaaaaaga cataaattaa
     7321 cgtagataga taatttatgt cttttttaac taaaactaaa ttattttatg atttagtttt
     7381 gtgaagtctg atagtctttt attttttggt taatagcaga tgcaatgaat tcttcaatgg
     7441 tagtgttggt tttctctact attttattaa ttgcttgata ttctttgcta gaaagtgtaa
     7501 ctggttttgt cacgctacta ctatctaaat atatactatt atttacacgc tttattaatt
     7561 ttccttctat tatatatggt gttaagtatt caatccattc catttgcata cccataggta
     7621 attcaatcag agattggcgt atatcgaaat accaaaaacc ctcctcttct gataccttta
     7681 ggtttcttgg tgatacgtac tgaaggatta agtcaatcaa ttggaaagag ttgctgcgta
     7741 attgatcgga cttaggtaaa cggaatttaa caaacctttg atgatgacta cgtggtttat
     7801 caggtaaatc gtatgctggt acgaatcccg atttaatagc ttcatttaag gtgaactcac
     7861 ttccaaattc atcaatcaac ataatatcac cacgcttagg aatagaaatg accctagcta
     7921 tcgtattact ttgaatatat ttatggaaaa ggactgtatt atacttttgt gagtatgtat
     7981 atagcgtgtt ttcttgatca aattgtttta taacttgaag taactcttct tctctaatga
     8041 atttagtttt gcggttacga tgttcccgta tagtagcggc taattcccca tcccctaacc
     8101 atttttctaa ttgatatgtg cttataccat attttttact agcttggtaa agggtaatac
     8161 cttcggtttc ccttcccttt ttaattgttt ccacatcttc tcttttgaaa aggaaacttc
     8221 catctaatcg ccatgtatcc ttgttgattg gtactaattc ttcctgtttg attaaattat
     8281 taacaacgaa attactaact tctaaatatt ccctcacttc gtttgtattc ataatcattt
     8341 gctgattctc attcataatt cctctcctct tgtatttcat ttgtatttat tttaaaaatt
     8401 atttaagtct aattttaatt ttaaagaata tataacttta attcattata acatatttaa
     8461 agtttaatct ttttacatac tttaataaaa acaatttata tttactaatt aaattaattt
     8521 ttatatttat ttaaaaatga taacaaaatg gttatataag ttagattgat ataaccatag
     8581 aaaatgggcg tttttctatg gttatatgac actttcattt ttataaagtt taattttgct
     8641 atgtaaataa tttttaatgt aattcaggta taatagtaaa tacaaaagaa attaataagg
     8701 agttgaataa caatgaaatt tgaattaatt acaattcata gtggaaattc tttagaaaat
     8761 atagagaaac aaaaacaaaa tttcgcaaac ataattgcat tatggaatcg tgattatata
     8821 aatgaagctg aatttaaaaa ggaaaataac gaaagagaag attcatatac atatgaggga
     8881 ttttcagatg aagaaatttt gtactactac ttaaatcggc aaacacattt tgaccaagaa
     8941 aaacgtataa aggatgcatc caggactcta tatgcacgtg atctaagcca gttctatttt
     9001 tttatcaaac aaagtacaga atttctgcag caagatgtta aagattatgt aattggccaa
     9061 gtttggagga atttaagaaa acgacatatc agaaactacc aaaagtggtt atcccaggag
     9121 gcattctcct atcaatcaaa agaaaagtac aaagcatcta cgattagtag aaaacttggt
     9181 gtaatccgct cttacttgaa atggttgtat gaaattcaat atatccggga acctcttcat
     9241 atagagattc taagtacgac cgttaataaa caacataaac ccaaacgcga gttatcatat
     9301 gaggaagtga agcatctgct acattactat aaggacaatg aaatcaatta cgctttatta
     9361 tcggtcctgg ctactaccgg attacgtgtt gcagaagtcg ctcatgccaa atgggaagat
     9421 cttgagtatg acgctatacg tggacgttac tatttaacag ttgatacaaa gggagataat
     9481 gaacggattg tttctattaa taaggacatt tttaaccgta ttgttgcatt tcgaatccgg
     9541 agaaggttac ctgtaaacat tgggaataaa aatggtggga ctatatttca aacaaagaac
     9601 catactgctt atagagagaa ttatttgtca caatatattt ctaaaattat aaaggacacc
     9661 aagttacctt ttacagagaa tatacgaatt acccctcact tctttagaca tttttatgta
     9721 cagtacttat atgattataa ggggctagca cctcatgtca tagcggctgc agttgggcat
     9781 aaaaatgata gaactacaaa agaaaattac ttgaagcaaa gacttacaaa ggataatgat
     9841 gtaggtaact taattggtga tgatgaattt taatgtgtaa ttaacatata ataaaattga
     9901 aatagggcaa ggttaaacaa atatcccgtt tcaccttacc ttgtccgttt gaattgtttt
     9961 aaatatttat actgcataga cttcaatcaa taatataatt ctatctctct atcaaattta
    10021 aggtttcact tcgaagtgta ctattatctt taaatattcc tttatatgat gaagttatag
    10081 tcattgaacc aggttttttc acacctctca ttgtcataca catatgctca gcttcaatta
    10141 ctacaattac accttttggc tctaaagttt caaaaattac atttgctaat tcattggtta
    10201 ttctttcctg taactgtggt cttttgcata tggtttctaa agctctagct aatttgctta
    10261 acccagttac ttttccatta ttaggaatat aacctatgtg agctattcca aaaaaaggta
    10321 ccaaatgatg ttcacacata gaatagaacg gaatttcttt aactaatacc aattcttcat
    10381 gattttcatt aaatattttt aacaaatgtt cagaagggtt ttgacctaaa ccttgaaaaa
    10441 cttccttata catttttgct actcgctttg gggtttccaa aataccctcc ctattaatat
    10501 cttctccaat tgcttcaaga atcattttta ctgctacttc aattttgtca gtatctatct
    10561 ctacactttg gattgttttt aagctcatat attatctcca ccttattaat ttattcataa
    10621 aatgccctta tttatacgcc tcgtttattt ccccatacta aagcatgaag ttgaggtaat
    10681 acttttgcat cattcatttc tttacactgt acaacttttt caatcaaccg ttcatatttc
    10741 tgtaataagt ttttaataag cgctgcatca tccaccgttt tcgtatcatc gttcccaact
    10801 tgtaagaaaa atggtacttg cggatatcgc ttgtgcacct ttactgcata ttcaaaatcg
    10861 taatcttcaa atacaactac ttttaaacta aaattttttc tttctaattt atggataaca
    10921 gaatctagca ttgtaaaatc tgttttcatc ttcgaacttg gtggttttgg cgaaattgtc
    10981 acttcttcaa tttgaagcaa ccattcttgc cacttactcc cttgcgtctc aatcgctgta
    11041 cgaattccat tctcttttaa tacagtaaga agaaactgaa tatttttcag caaaacggga
    11101 tttccacctg aaattgtaac gtgagaaaaa ttttctccac caattccaac aagttcattc
    11161 caaatttctt ctggtgccat ttgtctaact tgttcttttg ctgagccatc ccatgtaaag
    11221 gctgaatcgc accaagagca gctatagtca caacctgctg tgcgaatgaa catcgttttt
    11281 tgtccgataa ccattccttc tccttgaatg gttgggccaa atatctccaa cacaggaatc
    11341 ctactcatca agtatccact cccgtcttac ttctgcataa ctcgttggtg tttcaaagag
    11401 acgtacgaat tcgacacgag ctcctttata ttcttctgct cgattccctt ttattaatgc
    11461 ttctaccatc ttttcataaa tccagacaac catattttcc gcagtcgtat tcatcactgg
    11521 taatgtctca tttaaatagc gatgatccaa ataaatctct atttcgtttt tccaaatttc
    11581 ttttatatct ccaaagtcaa ttacaagtcc aatgtcattt acatatccac taataccaaa
    11641 tacaactttg tatgtatgac catgtaaatt tttgcatttc ccttcataac agtgcaaatg
    11701 gtgtgctgca tcaaatgtaa attccttgct aaccattact cttttattat ggtattttaa
    11761 ttgctcaagc tgaatatcct tgtccatttt ttgtaaattt tctacaatgt gaaacccgaa
    11821 aaaattttcc attattcatt ctcccctttg cgttcttgta ggtacgtatc taatcctact
    11881 ttacgaagtt gacatgctgg acattcaccg caaccatcac caatgattcc gttataacat
    11941 gttaatgttt tttctctaac aaactcgaat gcgccaagtt catcagataa tttccatgtg
    12001 tctgctttat caatccacat aagtggtgta tggatgacaa atggataatc catagataaa
    12061 tttaatgtaa cgtttaacga tttcacaaac acgtcacggc aatctggata accactaaaa
    12121 tcagtttcac atacacccgt tacaatatga cgtgctccaa cttgttttgc taatacagca
    12181 gcaaatgata agaatagtaa attccgccca tctacaaatg tcgatggtaa ttccccttct
    12241 tcatgtgtaa tctccatatc tattctggtt aacgcatttg gggctagctg atttagtaag
    12301 ctcatatcta tcactttatg tttaatgcga agctcgttcg caattttcgc tgcacaatca
    12361 atttctaact tatgacgttg attgtagtta aatgttacag cttccacctc tgcaaattgt
    12421 tgcattgccc aaaataaaca tgttgtgcta tcttgtccac cactaaaaac aactattgct
    12481 ttatcattag agtacatttt attctcccct taactacttg cactgttata atatcttaag
    12541 gcaaacttcc aaaaataaat tgaaataata aaaaatccaa tagaataacc caataaaacg
    12601 aatacatcgt ttagttctaa tcgaccaatt aaagcataag ttggaatatt actaacaata
    12661 acaataggaa aaacaaataa aaaaacaaat cgacttattc ctttatataa ggaagatggg
    12721 tatctaagta atgtcatagt accaagaaat aactcatgca taccttcaac tttggttaac
    12781 catatagata aagtcattaa aataaaccac agagaatacg agagtataat ccctaaaaac
    12841 aatagaccca agaaagaaaa tccatttaca atactaacac tctctccctt ttgtaataat
    12901 gcataactaa ttaacaatac ggctggtaaa cagttcccta agttgcctaa atcaagcttt
    12961 cttaatgaaa ctagaaactg actattaata ggtttaaaca atatctgatc taaacttcct
    13021 tggttaacta aactcggtat atacggtaga ttattaataa aaagagtaaa catcaaagat
    13081 tttatcaact cacttgttcc aattaacaaa taaatatcat ttgtattcca accattaata
    13141 ttaccaaaac tatcaaatat actattaaaa aatactaaag taacaatgaa ccaaacaacg
    13201 ctatctaata tatttaaaaa aaagttaact ctatacatca taatattact taaattaatt
    13261 ttaagaattg cttttaacat ttttaaatat ctaatcatat ttatgcacca acagattcat
    13321 atttatttaa ccccttcttc caaagtattc taataaggac atagaaaact aaagaccata
    13381 tcacttgtga aattaatcca tttacaattt cagtgccact taactttcct aaatatacat
    13441 ttaccggaaa gtgaattaag tatgaaaaag gtaaaaaacg agttattgta tttaatggag
    13501 ctggtaaaaa ttcaagcgga ataagcgatc cagataataa ttctaatact atatctacag
    13561 taaagaaaaa ggatgatatc tctacaaagt aaaatgagaa gagtgatatc aaataataaa
    13621 ccatataata tagtattgat gctcctacta ttgaaagaat gaacaggaaa gtatatttta
    13681 aagtaggcaa aaggaaataa tccctgttca ggaatattat cggtattatc ggtatcactg
    13741 acatcagtaa atgaataatt ttgttaccta aattatggct aaaccagtat ccaaaatatg
    13801 aaaatggttt tataagatat tttgataatt caccggattg tatttcctca tttatcgacc
    13861 agtgcatttc aggaattagt aaaagttcaa ttaacttagc aattattaca taagtaatca
    13921 tcatttcaag agtataaccc tgaatattgc tttgtgtttc aaagagagaa tgccacaata
    13981 gtattaaagc cacaagcggt attaaaccaa aaatcatata taatacaaca ttcatgcgat
    14041 actgaaaaac tgcttgaaat gaaagcatca ttggttttaa atacttcttc atactgttat
    14101 tttcactcca gtcgattcca ttgaataaat atcttcaatg aggtcttgtg atgacatttc
    14161 agtcaaattg tagtcaataa cattgaattc ttttaatatg ctagatatgg tctcgttcac
    14221 taacttatct tgaactttta ttgttacact aaatttatcc gactctttaa cttctccata
    14281 tttcttaaga tcttgagaat ttatttcatt ttcaaagcta agatatatat atttataact
    14341 cttaatttct tcttttattt ttttgaaatt gttattaaaa acaacttctc cattcttcaa
    14401 tattattaat tcttcacata gctcatatat atccgggaaa taatggctag ttattacaac
    14461 tgttgtattt ctttctttgc aataattttt gaggaaattc ctgatattct tttgagcaag
    14521 aaaatccaat ccaatagtcg gttcatctaa aaataatatt ttaggtgagt gtaatattga
    14581 agcaatcaac tcacatttca ttctctctcc taacgataga ttccttactg gcgatttaag
    14641 aatttctgat accccgagat ttttagctaa ttcatctaca ttctttctga actctgtatc
    14701 agacagctca tatatttctt tatgtaataa aaatgtttcg taaggggaaa gatcccacca
    14761 tagctgattt ttttgtccta aaacaacgcc aatagacttt aaaaaatctt tcttcttatc
    14821 atgagggtta aatccattta tcaagattct cccggaagtt ggtttaatta acccaaccat
    14881 ggctttcatt agggtagact taccagcacc attcgcgcca ataagcccta ttattttacc
    14941 ttcttttatt ttgaatgaca catcacttaa agcagtaacc gtgacctttt ctcttttaaa
    15001 taaactcttg aaagagttta ttaatccttc ttcaattttt actctttcaa aagtttttga
    15061 tacattttca atttcaatga tatccatctt ctctctcctt tttactactt acttaccacc
    15121 ctaaaaactt ctgcaaattg cactcctgcc tgcatacccc tataagcatt cagccccaaa
    15181 actccatcaa ccaaatttaa tgttttaagt tgggattcat attttttaat tgatgctttt
    15241 ttcagttcaa taaacctggt aatatctttt acaacctgat agtttttcat gggagtccat
    15301 acttcatact gtaaacacat cggagcaaaa ttctctttta agaaccccga ttgacacagg
    15361 aatattgctt ctgatacaac ttcatttact attcgatgat ccctatcact ttccatatca
    15421 tgggggaaat aaataaaatt aggcttatat tttgagattt catgaataat ttcttccaca
    15481 aaatctaaag aatacacaag tgatctgtct ggtttcttta aaaatttaat atctcctttt
    15541 tctatcccta atgtattaca agcatttata cactcgttct ctctatttga aataatttca
    15601 tttaaatctc ctactcctcc agataaatct ccttttgtaa ttattattac ttttatatgt
    15661 tcacccttac taatagcttg agcaattgtt ccaccacagc caatgacttc atcgtcatgg
    15721 tgtggcgcta taactaaatg tttttttaca atatccttca ttcagcatca cctttattga
    15781 ataggtaaat catttaccta ttattttaat taaaaattat ttactctgga gtatactaac
    15841 tggatacatt ttattttcac tagaaaaata tactttttaa gagcgtctat tcacactgta
    15901 tatcattaaa atttccccct tgcttcctac attcgtacac cataaattca ctattcctcc
    15961 caaaaggatt tttattgtaa tcaccataaa aattttttat actgaatcct tctatttcta
    16021 agagatactg catttcggat ggtaaagtat attttgcaag aaatctaaaa tttttttcac
    16081 ttaaaaaatt atctgttatg tcataaacct caaaataaca agtggtttca actatttgct
    16141 tataatgatc tgcttttacg acatcccatg atttaatttt atatttttta aaattctccc
    16201 ctttaatagg actatttcct ccatcactca ctctcttaga ataaggaaga atagttggag
    16261 gtgtaataat atcgaaaaca aaaatcccgt cttcttttaa tagtaattta atgttcctaa
    16321 gagctaattt ttgttgtgac gatgtaagta aatattcaaa tacaccacca gacataaata
    16381 taaaatcaaa ttttctttca gacttaaaat ctgtagcaga agaaacctta aattctattt
    16441 tatccttaat atttggcatc tcatctaact tcttactggc tttttcaatc attcctgctg
    16501 atatatcaac actagttaca ttcgcgcctt tttcagcaag aataaaagat aatctaccag
    16561 taccgcaccc caaatctaaa acttcatcat ttgcttttac caaaccactg taaaaatcaa
    16621 aaataccatc aggttctggg ataataatgt cgtataattc agaaatttca tcgtattgtt
    16681 gctgcattgt tttcctcctt aatgcatttc ttttttatat cccctataaa aggcaagctg
    16741 ccaaaatatg agatagaaag cagttaaata accgtatttt tttttaatat acttatatga
    16801 gttaataatg gacttcgttt tatttttagg ttcataataa ccatcttttt tgtgtaaaac
    16861 cccacgtgca tgacctacac cataattaaa tgaacttttc aaatcttgct taatgcttaa
    16921 ctctggatga ataattcttg ctttatcatc atataaaatc ttaagatttg cagatttaac
    16981 tctaatatca aaatcataat cctctgtcca agataaattc tcatcaaaat aatatccatt
    17041 taccttcgct aagattgctt tattaaatgc caatggaggt gaatatgcat tttttttgca
    17101 agtatgtata tgtcttgcgc gtgcaatgat ttttccaatt ttactgttaa aggaaaacat
    17161 cacccttcct ttagccaaag gtcctgcatc taataatttg aataacttat tgatggtacc
    17221 tggcataaaa acacaatctg aatccataat taacacatta tctttactag aaatttcaat
    17281 tccataatta taagcttttg ctaaattagg tgtaggtaat tccccaatta ctgcattgct
    17341 agaataagcg atttttttta cttcttctgt tgcaccattt aagacaacga caacctctac
    17401 attttcatca atacttttta aacacttttc caatctaaca tcattataag ccggtattac
    17461 aattgataga ttcaacatat ctactcacct tatttaaaca attatccata ctactcaaaa
    17521 cttcatctaa acaataaaat tctcctgaat cctttaactc gactaattta tctttattat
    17581 ttctatatgt ttctatatct ggggttaaaa gaaaagtaat tcctagatcc ttacaaatat
    17641 ctttaattac aggagccatt gaatattttt ttaccggtat accatattgt actactacat
    17701 cgtatgaatt tgattctagg tagctcctaa ttctttgtat caatttatcc ctatattctt
    17761 tcattaattc ttcataaatt actggatcct caatgtcatc catccaatcg tacgcacaaa
    17821 aagtaggatt catttggtat tcatatggta taattcccgc atttgataga ataattggat
    17881 gaaccattgg gtatttattt gtaacttctc taattttttt accaatatat gaaaaatcat
    17941 atggtttagc ccaagaacat acttgtaaaa aagcaattct tttcccttga ggcttttcgt
    18001 aataatcccc acaaaaatat tcctgccatg tattaaactc ttcgtgatga atatactttg
    18061 agcaagctcc tcgtttaaaa actgtttcct cttttattaa atctaatagt atatattctg
    18121 ggtagtaagg ataacttttt ttattaagta ccaaatcctt taccttttca tcctgtagat
    18181 tagaataatt tctatttctc aaaatctctc ctcctttatt taagaattaa aaatgaacct
    18241 aataaaaggg catccatctc tgatccataa aatgacctga tagcatcact tgggttacat
    18301 ataattggtt cttttcctac attaaacgat gtattcatta ctgcaggaat tcctgttttc
    18361 tggtaaaagt tatagattgt ttcataataa tcagaattca tatccctcgt aactacctgg
    18421 gcccttgttg atccatcaac atgaactatt gctggaacta aatgatgtac ctctttttta
    18481 acagtagaat ttaacagcat ataagggtta tttattcttt cttctaatac tacagaagcg
    18541 ttttcatcta tgatactagg agccaatggt ctccattgct ctcttttctt aatggtattt
    18601 actttattta acatatcctt attctgaggg ttagctatta tgcttctatt tcctagagct
    18661 ctaggaccga attccatctt tccagaaaat cttcctatta tcttattttg cattaataac
    18721 tcggagcatc tatcatattt attagaacct aattctatat atgacaaatt atattttttt
    18781 aatatattta agatactaga atcagtaaat tccggaccag aatatacatg atctacagtg
    18841 aatataggcg ctataccatt ttctgcaaga aaccatgtag ctgctccaat acttacccca
    18901 ctatctgaag cacctggttg aatgtacaga ctattcactt ctggtaaatc agctataatt
    18961 ctatttgcta tacaatttaa tgctactcct cccgaaagac acaaattatt aattccagtt
    19021 agattaacag ctttttttac aagcttaaca attgcccttt ccaaggctgc ctgacctgag
    19081 gctgcaatat ttttatattc cattactgat gaattcatta atagtattga atctattgga
    19141 ttatattcat atttaatata attaggagct atctttgtta tactattaat aacttttatc
    19201 caatctttta ataccgaaaa atatttacca ttcatactaa ctgtatttct atttggtttc
    19261 aaaggatttt ccagtatttc aggaaattca aatatttctt ccccatatga agataggccc
    19321 attaacttcc cttcattatg cctccctaaa cctgaaaata cagttaatgc ttcataaaaa
    19381 atacctaaag aatgttctaa cgggtatttt tctagtactt caattatatt accttttcct
    19441 tttgctatag ttattgactc ttcttctcca cttccatcaa taactattat ggtagcttca
    19501 ttgaatcctg aactaaagaa cgcaccagaa gcatgtgcca aatgatgaga acacatatgg
    19561 atttgaggat ctttatctct cttgaaaatt ctcttcggaa aaatcttttc aagacattca
    19621 tctttgttaa gcttctttga atacttctca aaatataatt gttctacatc ccagcccata
    19681 acaatatgat ctacttcatt tggagtaatt tcagcttcct ttaagcaata agctattgaa
    19741 ttatatggaa ttttatctaa tgcttttttt tgacgaataa atctttcttc ttcagctgca
    19801 gctattaatt taccattata aaataaacac gcacttgcat catgaacatc aaagtcccac
    19861 ccattgactc ctaaaacata cattatatta cctcgcagtt attttatatt tttcttctaa
    19921 tctcataata ttcttgcgga aaaagggttg gtttatctat taatcttaca aaaactaaca
    19981 tatccgtttg aatatataaa ttttggaatg tatctttaga aaagcctatg ccatctaagt
    20041 ctttttttat taattcttca tcaatgtaag gctcttcagc cactttataa gaacttaaat
    20101 cgtgaataat ttcttttaaa taaaagccta aagatgtcaa gaaattctgc aaataaaccg
    20161 ccctattacc taatctttta acacttatat ttaaaaaaat taaatcaccc ttttgacctt
    20221 ttaataattc attagctcta tttaaccaca aatctaaccc tctaccatca tctatagggt
    20281 cacaatgtat tgcatcatac ttattcctta aatcttctat aacttcattt ctaacatcaa
    20341 aattataaaa cttaatatca ttgtctgtac gtttaaaata ttcaatcaat tcttcgtcga
    20401 tatctcctac acttatttct ctgtttttat attgtttaag ggccaagctt gtataatcat
    20461 catctccgca aaaaaagata tttttattag atgataactc ttgatttatt atttcagctc
    20521 ttctcaacga actatcccaa gtagctttaa attgagcata tttttttttg tttattttat
    20581 tctcatatcc tgtattagga agagaggctg gttcatataa aatactactt gttaaatctt
    20641 gtgaaaacct tattttattt tctataattt caactaaatt tctttctttt aatactttta
    20701 ataatcttaa agccaaactt aaagtcccag ttattttgac cagatcatct aaagtatcta
    20761 cagtattaat ggccttccaa attataaatt cgaattgttt ttcactaatt tcataccatt
    20821 ttttccaaaa atgcaaaagt acccctctgt tttttaattt tggtacttta tctaactctt
    20881 cttcatagtc taattcaata aatctttcat ataataaaat aatcttattt tctttcatac
    20941 tgtataccct accttaaaaa agttacatat acagttaaac tgcatatgta acctccttat
    21001 tttaaaaact taacctaatg tcttgcctgc acgaattaat aaatcctctt catctaattc
    21061 aagatcttca agttctagca tttcttcatg aatatattcc ttttccattt cacattcccc
    21121 cttttaaaga taattgtgta gttcaaatat ttgcaacaga tctgcaccac caatattagc
    21181 ataaaaatag aattttctga ttaataaata aattgtattt gtagataaaa aatgttcaga
    21241 aaattaagta taatttttcc tgataaaaca ataataggaa taattatggg tatttatatt
    21301 attttagttt ttatattagg attttttaaa aacctagtat agagcctttt cttagagatt
    21361 tttgtcgatt ttctttttta taaatttttc aaaaaatgtt tattttcgag ggctattggg
    21421 gggatgtcta ttttttgggg gcacgataat ttgaagtgcc cgcataaatt agacaggtta
    21481 tttcattagg taactttttg ggttctggtg caaaaatatt atttagagac ataatgaagg
    21541 atgtgcattt gacgtaaata tggagtttgt ggaacgggtg aaagatttac cgcctacttc
    21601 agataagaaa aagtatttat ttagagaaat cattacttat gatgtacaag gtaatcctat
    21661 aacagaagtg tttaaatata ctgttgttaa tacagggatc ctgaataaag tttgtaataa
    21721 aaccccatta tctaacatcg gcgcagagtc tggtgatatt tataaaattt caccacacca
    21781 gttcaggcac acggtggcta ccgaaatgat tgatgctggg gtggatattt acgctgttaa
    21841 aaacttctta ggacattcat ctgttacgat gacggagaat tatattaaag tgtaccaaca
    21901 acgattaaag aaagagttca aagaaaaact acttaaatct gatgccactg caattaaaga
    21961 gaatctacct ggacaagaag aaatctttgg cgataacaag tgggtcaaaa ataagattat
    22021 cgctattttc gaccaaggtg atgggtgttg tgagcatcca tataaaatgc cttcctgtcc
    22081 ccatcaagtt gcttgtaaaa cgtgtatcaa gaaaaagata ctcccaagac ataagaacgc
    22141 tgttgtagat accatagacg cgttcacaac ccatttaaac caagctaaac agattgggct
    22201 tgaagaaaag attgaggaat ttgataaagt tgtgcagttc taccaaaatg cattggaagt
    22261 catcaaaaag ggtgaaacgt tcgacgcagc gaaacacttt tacactggag gggttcattg
    22321 atggctaata tggggtacag ccgagatacg tgtaaaaata ggtcatagcg atacattttt
    22381 ttccagacgt tatttttcgg agacatttgt aacataaacg cgttcgtttt tgttacgttt
    22441 tgtgtttgaa aatatgaaat atcctaattg ttgaactagc tgtaacaaaa tactgta
//
