LOCUS       NZ_CP036016            22709 bp    DNA     linear   CON 25-JUN-2024
DEFINITION  Bacillus toyonensis strain BPN45/4 plasmid p246.
ACCESSION   NZ_CP036016
VERSION     NZ_CP036016.1
KEYWORDS    RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 246340)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 246340)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 191.4x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739605.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:09:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,850
            CDSs (total)                      :: 5,697
            Genes (coding)                    :: 5,477
            CDSs (with protein)               :: 5,477
            Genes (RNA)                       :: 153
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 220
            CDSs (without protein)            :: 220
            Pseudo Genes (ambiguous residues) :: 0 of 220
            Pseudo Genes (frameshifted)       :: 93 of 220
            Pseudo Genes (incomplete)         :: 130 of 220
            Pseudo Genes (internal stop)      :: 65 of 220
            Pseudo Genes (multiple problems)  :: 52 of 220
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70177
            Orig. end                         :: 92886
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22709
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22709
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22709
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12709](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12709
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            436..729
                     /locus_tag="EXW33_RS29505"
                     /old_locus_tag="EXW33_28865"
     CDS             436..729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002191565.1"
                     /locus_tag="EXW33_RS29505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28865"
                     /product="hypothetical protein"
                     /protein_id="WP_001232687.1"
                     /transl_table=11
                     /translation="MRKTKLRNYVKLFILYLIIISIYFLLFDYSKVYIKTKINNEFLYQ
                     LYLLIGRISMGLGIYFIPDKLGIKIKFRFKFLIAVIAMITTIIFLDIVGLME"
     gene            884..1549
                     /locus_tag="EXW33_RS28120"
                     /old_locus_tag="EXW33_28870"
                     /pseudo=""
     CDS             884..1549
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016102633.1"
                     /locus_tag="EXW33_RS28120"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28870"
                     /product="IS6 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCDRYGKENWFKWKQYQPDIILLTVRWYLRYNLSFRDLVEMMEER
                     GLSISHTTIIRWVHQYGPELDKRMRRYLKPINDSWRVDETYIKVKGQWMYLYRAVDSNG
                     NTIDFCLSKTRDHKAAKRFFKKALRSFHVSKPRVITVDKNPAYPIAIEQLKKEKSIPSG
                     MRLRQQKYLNNIVEQDHRFIKK"
     gene            1832..2038
                     /locus_tag="EXW33_RS28125"
                     /old_locus_tag="EXW33_28875"
     CDS             1832..2038
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EXW33_RS28125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EXW33_28875"
                     /product="hypothetical protein"
                     /protein_id="WP_000995297.1"
                     /transl_table=11
                     /translation="MNAYGKMSIQQGCTVWALILLFGGFIVWLFAGSSSSYDSNKGANN
                     PYMNDKKREQINVMYNFKNEIEV"
     CDS             2505..2621
                     /gene="allorf_072682_072798"
                     /locus_tag="allorf_072682_072798"
                     /protein_id="allorf_072682_072798"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MYFRDVVFIAICKDVVLLFHKVEYNRMAYFITCILSIR"
     CDS_motif       2505..2534
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MYFRDVVFIA"
                     /locus_tag="allorf_072682_072798_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2535..2621
                     /prepeptide="core"
                     /locus_tag="allorf_072682_072798_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="3353.1"
                     /monoisotopic_mass="3350.8"
                     /core_sequence="ICKDVVLLFHKVEYNRMAYFITCILSIR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYFRDVVFIA"
                     /leader_location="[2504:2534](+)"
     misc_feature    2575..2591
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 20.97"
                     /tool="antismash"
     gene            2650..2874
                     /locus_tag="EXW33_RS28130"
                     /old_locus_tag="EXW33_28885"
                     /pseudo=""
     CDS             2650..2874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332356.1"
                     /locus_tag="EXW33_RS28130"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28885"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNGCYQFAPCICEAGNHSPEEVERRRHGVMAELRESHQLQLEGK
                     "
     gene            2831..3076
                     /locus_tag="EXW33_RS28135"
                     /old_locus_tag="EXW33_28890"
                     /pseudo=""
     CDS             2831..3076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002153818.1"
                     /locus_tag="EXW33_RS28135"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28890"
                     /product="helix-turn-helix domain containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTLQQGWYMKKLRRNLYIVLEELDLVFNESEVMQLRKMWD"
     gene            3073..3336
                     /locus_tag="EXW33_RS28140"
                     /old_locus_tag="EXW33_28895"
     CDS             3073..3336
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811979.1"
                     /locus_tag="EXW33_RS28140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28895"
                     /product="hypothetical protein"
                     /protein_id="WP_000826925.1"
                     /transl_table=11
                     /translation="MKRLTLEGVVGSFDYTETSTVDKFLKRNSVMTYSVEFYEKDEKWK
                     LRRFEAKSESEAIEMAKEKYGKIEIITTYISDRTLEGIIHFD"
     gene            complement(3646..4119)
                     /locus_tag="EXW33_RS28145"
                     /old_locus_tag="EXW33_28900"
     CDS             complement(3646..4119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016081630.1"
                     /locus_tag="EXW33_RS28145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28900"
                     /product="hypothetical protein"
                     /protein_id="WP_000342733.1"
                     /transl_table=11
                     /translation="MDDRSSRQWKMRQKLRELKTKNRSDTNPLFNECLESLGNETLISS
                     QEKSQQIATTLMNLFPITVSGRIDWEQIDTQLIASNKKQLISLIRAHQLDFDEQIFIIW
                     DNYEIPVVSTNLDKVFQSLVDVDAVSFYYWLLDKEYRFVIEINNEELIKVGFR"
     CDS             4738..4857
                     /gene="allorf_074915_075034"
                     /locus_tag="allorf_074915_075034"
                     /protein_id="allorf_074915_075034"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFHKCIKKVNKKDILIVLAPWRALQGAKIREFLNSCLII"
     CDS_motif       4738..4818
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFHKCIKKVNKKDILIVLAPWRALQGA"
                     /locus_tag="allorf_074915_075034_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4819..4857
                     /prepeptide="core"
                     /locus_tag="allorf_074915_075034_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1430.8"
                     /monoisotopic_mass="1429.8"
                     /core_sequence="KIREFLNSCLII"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFHKCIKKVNKKDILIVLAPWRALQGA"
                     /leader_location="[4737:4818](+)"
     gene            complement(5152..5274)
                     /locus_tag="EXW33_RS29510"
     CDS             complement(5152..5274)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="EXW33_RS29510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_206352928.1"
                     /transl_table=11
                     /translation="MTESPDLSGGTTIPCGELAVVITAAFCPTSKCTTRCGLRG"
     CDS_motif       complement(5203..5274)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTESPDLSGGTTIPCGELAVVITA"
                     /locus_tag="EXW33_RS29510_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5152..5202)
                     /prepeptide="core"
                     /locus_tag="EXW33_RS29510_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.40"
                     /molecular_weight="1628.9"
                     /monoisotopic_mass="1627.8"
                     /core_sequence="AFCPTSKCTTRCGLRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTESPDLSGGTTIPCGELAVVITA"
                     /leader_location="[5202:5274](-)"
                     /alternative_weights="1646.9"
     gene            complement(5290..5505)
                     /locus_tag="EXW33_RS29515"
                     /old_locus_tag="EXW33_28905"
     CDS             complement(5290..5505)
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="EXW33_RS29515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28905"
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="WP_080023449.1"
                     /sec_met_domain="mature_ha (E-value: 2.9e-10, bitscore:
                     33.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGGVNGKMFKLKKENISELAKESYLNQLDKSDKRLENSFGADCT
                     WWDLSCHLGNDGSTCTLSVECRPACW"
     CDS_motif       complement(5380..5505)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLGGVNGKMFKLKKENISELAKESYLNQLDKSDKRLENSFGA"
                     /locus_tag="EXW33_RS29515_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5290..5379)
                     /prepeptide="core"
                     /locus_tag="EXW33_RS29515_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3151.5"
                     /monoisotopic_mass="3149.3"
                     /core_sequence="DCTWWDLSCHLGNDGSTCTLSVECRPACW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLGGVNGKMFKLKKENISELAKESYLNQLDKSDKRLENSFG
                     A"
                     /leader_location="[5379:5505](-)"
                     /alternative_weights="3169.5"
     gene            5894..6241
                     /locus_tag="EXW33_RS28160"
                     /old_locus_tag="EXW33_28910"
     CDS             5894..6241
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="EXW33_RS28160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28910"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_141507159.1"
                     /transl_table=11
                     /translation="MLNKCVIYLEKYINKILVDLETFKNGFYFTDLKSISLDAGDSHAE
                     GKSVCIINLDDTCYIYKPRMTELDQRFMKLIQSQIREYNFTIYSYDTLSIHELIVYKSP
                     ESIEDIEKYYL"
     gene            6448..6591
                     /locus_tag="EXW33_RS28170"
     CDS             6448..6591
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EXW33_RS28170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_002156205.1"
                     /transl_table=11
                     /translation="MNVSALTGGEAVYNDFYYKQKVLVDYNNDSVRYEEAPIALEDKPN
                     RI"
     misc_feature    complement(6727..6745)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.01"
                     /tool="antismash"
     gene            7866..10004
                     /locus_tag="EXW33_RS28175"
                     /old_locus_tag="EXW33_28920"
     CDS             7866..10004
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="EXW33_RS28175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28920"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_001228039.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.5e-34, bitscore:
                     110.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKVPYVGQVQESECGLCCVSMLMGYYKQFIPVKTLSKTIEVGR
                     DGVHIKKLGEVLDSFGYNVSYYEADSNSLIQIADKPLILFWNKNHYVVLEKIKNGMFYI
                     VDPNFGRGKLTLEEFNEHFSNIVLLADPTEATKKINLKENPFKMYINYFKGKYWDLIAL
                     LICSILSTATVLLVSIFMKNLIDRTTASSNSILNSNMVIGLLGLMIMFLVFDLLKSNLV
                     IIFSAKLDKSIYTSVVNKLFRVPYKFYLTRSSSDILFRLSLLKSNRNFFIETLIKSILD
                     VGMLVFVLIFMLFIDPILCVSLIIISILLGLFLYFIRKLIILKNKEEIIEGTKLQGKEY
                     ETLLAISYLKSTGQEEYIKSLLLNQYDVALNKYKEKSFIDNIYGNITKFVSYFAPLLMF
                     FLVLSLYQQSILSLGTVMLVYSISNYYFTSLNGVYSSFNVYGTLQNNLERIVDILEEQE
                     DHYFIKEGTITVDEIKTISFDNVSFRYPGQTDYVINNLTFTVNKGEKVAIVGETGSGKS
                     TITGLLLGLFIPEKGTIKINGINIEDVNRESLKSLLGYVPQSPNIFNKSIKENILMNRD
                     INEKQLIVSAERASISNDIEKMPMKYETVISEMGSNLSGGQKQRIVLARAIIDNPDLLI
                     LDEATSAVDNVTEAFISQFLQQANMTQIIIAHRLGTIIEADKVIVLQEGEITNIGTHSE
                     LLNRSDLYKQMYDRELNS"
     gene            10001..12709
                     /locus_tag="EXW33_RS28180"
                     /old_locus_tag="EXW33_28925"
     CDS             10001..12709
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="EXW33_RS28180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28925"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_000848290.1"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-48, bitscore:
                     159.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-44, bitscore:
                     145.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTIDSTNLISAVVHMQDNSLKWLSKKHKFSFVWTNIVEYLVSNK
                     HDLSHKEMKIFKGNINSLYSSCMSLVTPTMIFHLNTLYQQNQENIEVDFQTFYKEFQDT
                     FISDYTLREDVFSTYPELFRLIYNFFDQSIYNIKESIYLVDVHREELKNRFNIEEFDEL
                     SIILGEGDVHKAGKSTSRVSIGGKTLFLKWRECSFEKDFIQFQHKFLKNMGITNRINNL
                     KEVEGSNYYFQESIEPEGIFEEEHNEHYYQLGAFIFIAYLMGVTDLHYENIIIANGNII
                     AIDCETIATSKEREMPEYIDYDLAKSVYSTFILPFNTVKGAVLSGISSLSSQTMYVNDY
                     KIKITNRGIDLANRPLRTISNPNSEKDKSPYFLHTNEIVKGFEESYIEFLENKNQYIDL
                     LQTMLANKKHRVLKKNTYDYSALLWESYHPYLMTSYEERYGFFEKNSLLDNDEQILLYN
                     GEIPYIEELINIQEKYFDRFSYDDLKRQTVLIKESLEFDKVMYLTSNEKNNLLVEPTIG
                     DCEIDKYKDYLLSNSVVDNWITSIETGVTHEDTEYKEIELNIMPDTLYLGKSGVIKFLW
                     AYYDRKPNKQEEIWFKNVLKSFWIKLKKHIITNPKIQTGFYDGIGGLLHTMYFANKRYS
                     IFHDKELIQILMVIKKNISYDTQFDVISGSAGLLNALIDMYHDSGSEDLKKQLLDCITG
                     AETHLIIHFDDINCGWSFENPSDPNDIFYYYGYSHGLSGIIPQLYRSFLITNNDEIKQI
                     VDKSVKKMIMLYDNFERNWPTSSSVDTYYTNWCHGSPGVIYGLGILLKNGYVSKEINNI
                     IYEVLLRLVREEKPNLCLCHGSYGNDIIGKYCSEIIENNKLKTAFERKLDDNWLKLLNT
                     DNIIKVNKSYMTGITGIYYWKLNNNNLDHIL"
     gene            complement(13075..13782)
                     /locus_tag="EXW33_RS28185"
                     /old_locus_tag="EXW33_28930"
     CDS             complement(13075..13782)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002127399.1"
                     /locus_tag="EXW33_RS28185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28930"
                     /product="IS6 family transposase"
                     /protein_id="WP_033666119.1"
                     /transl_table=11
                     /translation="MGKKNWFKWKQYQPDIILLTVKWYLRYNLSFRDLVEMMEERGLSI
                     SHTTIIRWVHQYGPELDKRMRRYLKPINDSWRVDETYIKVKGQWMYLYRAVDSNGNTID
                     FCLSKTRDHKAAKRFFKKALRSFHVSKPRVITVDKNPAYPIAIEQLKKEKSIPNGMRLR
                     QQKYLNNIVEQDHRFIKKPIRSMLGLKSFETDTSILSGVEAMHMIKKEQIALRNQSVQN
                     QKEFIHQLFGLAI"
     gene            14031..14411
                     /locus_tag="EXW33_RS28190"
                     /old_locus_tag="EXW33_28935"
     CDS             14031..14411
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003337482.1"
                     /locus_tag="EXW33_RS28190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28935"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000845514.1"
                     /transl_table=11
                     /translation="MKTEFSPNVPIYVQVMEYIKKEIVTGRLAPGKKIPAVRELAGELQ
                     VNPNTIQRTFQELEREGITETRRGTGRFVTMNEEKITDLRKDMAKELLDNFINGMHNLG
                     FMEEEVLSILRSSLEKKKEGNE"
     gene            14408..15106
                     /locus_tag="EXW33_RS28195"
                     /old_locus_tag="EXW33_28940"
     CDS             14408..15106
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018674046.1"
                     /locus_tag="EXW33_RS28195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28940"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000661384.1"
                     /transl_table=11
                     /translation="MKELLKVENLSKRYDLKTVIQDVSLTISEGKIIGLVGEKGSGKTT
                     LLKMISCLRFPSTGSITIKDKKVGLETKKIVSFMPDSPVFEKWMTVKDALVFYRDMYAD
                     FNLQQALDLIANFKIPLEGNISILSKGKTGILQLILTFSRKATVYVLDEPLGGIDLVSR
                     KHIVDLILNFYREDSTILISTHLIGEIENIFDEVIFLKDGSIVLHENVEEIRFHHGKAV
                     HELFKEVFET"
     gene            15103..>15180
                     /locus_tag="EXW33_RS29170"
                     /old_locus_tag="EXW33_28945"
                     /pseudo=""
     CDS             15103..>15180
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068596.1"
                     /locus_tag="EXW33_RS29170"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28945"
                     /product="ABC transporter permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNPLFRYLFNCNGKKIAILYFGFITI"
     gene            complement(15159..15440)
                     /locus_tag="EXW33_RS28200"
                     /old_locus_tag="EXW33_28950"
     CDS             complement(15159..15440)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EXW33_RS28200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EXW33_28950"
                     /product="hypothetical protein"
                     /protein_id="WP_000014529.1"
                     /transl_table=11
                     /translation="MSGKDVWRWLLPKFSNESLVQRYTKQKNTFNGIRTNKIKDIINKT
                     NRNMLISNLFETKNYPKLMSWSKGVQPNLLEGLSLVDKEVNKIVINPK"
     gene            16146..17546
                     /locus_tag="EXW33_RS28205"
                     /old_locus_tag="EXW33_28955"
     CDS             16146..17546
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016106994.1"
                     /locus_tag="EXW33_RS28205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28955"
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="WP_000725197.1"
                     /transl_table=11
                     /translation="MKKIVSTLCIAGVTLTILGACPQSSYAHLDQIDLNENDPITARWS
                     AEAPYHSDKSTHLWIAKQAIEIMKTESNIEANKQAVDFLNYPQYKDLFSKGLYDADYNA
                     EFNDGGTGIGGVFKGGWKSHFYDPDTKENYRGETNPTALTQGKKYFYESGEHLRNKDYE
                     KAFYYLGVATHYFTDATQPMHAANFTAIDTRAIKYHSYFENYVTTIQNQFAVNTGGNYN
                     NSLSTPEEWIDYAARVAKPEIQNITNDKTFKYYNSGKAQLWQEMVTPAVQRSLGEAQRN
                     TAGFLNLWFKTFTENVKAPSIETALIYDIEGNVIEAGKNYYIVPSESPYQGLTFEWYIA
                     NRYDYVTLANKENNGLSGTPMEFEFYKENDAKLHHGESIYLRMKHSNYDQFQYLNWSNY
                     SSWIHLAQKSDSLADFKIKINLDNPTEYNIFTDDYPLNYENINAKKNWIVLGEKTQKPS
                     SWKFIPVR"
     gene            complement(17808..18929)
                     /gene="tnpB"
                     /locus_tag="EXW33_RS28210"
                     /old_locus_tag="EXW33_28960"
     CDS             complement(17808..18929)
                     /codon_start=1
                     /gene="tnpB"
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090861.1"
                     /locus_tag="EXW33_RS28210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28960"
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_000973298.1"
                     /transl_table=11
                     /translation="MMINKAYKFRIYPNQAQATLINKTIGCSRFVFNHFLSLWDHAYKE
                     TGKGLTYGTCSAKLPAMKKEFVWLKEVDSIAIQSSVRNLADAYTRFFKKQNNAPRFKSK
                     KNNVQSYTTKQTNENIAVVGNKIKLPKLGLVRFAKSREITGRIVNATVRRNPSGRHFVS
                     LLVETEVQELPKTHSYIGMDVGLKDFAILSDGTTYKNPKFFRSLEEKLAKAQRVLSRRM
                     KGSSRWNKQRVKVARIHEYMTNARKDYLDKISTEIIKNHDVIGIEDLQVSNMLKNHKLA
                     KAISEVSWSQFRTMLEYKAKWYGKQIIVVSKTFASSQLCSCCGYQNKDVKNLNLRKWDC
                     PSCRTHHDRDINASINLKNEAIRLLTARTAEIA"
     misc_feature    complement(19075..19084)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.33"
                     /tool="antismash"
     misc_feature    20067..20080
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     misc_feature    complement(20077..20090)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     gene            complement(20373..21164)
                     /locus_tag="EXW33_RS28215"
                     /old_locus_tag="EXW33_28965"
     CDS             complement(20373..21164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677291.1"
                     /locus_tag="EXW33_RS28215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW33_28965"
                     /product="carbonic anhydrase family protein"
                     /protein_id="WP_000677290.1"
                     /transl_table=11
                     /translation="MKGLKFVYKTPLILTMSVVLMGCNTAKQEAPQKQSTKENTQWSYK
                     GTTGPEHWGELKPEYNMCLNGQEQSPIDIKTEQIKSTVDNNLLQINYQPISFSIKNNGH
                     SIEGKANSSDDYLTLGENRYTLKQFHFHTPSEHQFEGKHADMELHLVHQNDQGQLAVVG
                     IMIKEGQKNEGFAAMWQNLPHRKNIKADVQHTIDIKQILPSDHSSFRYMGSLTTPPCTE
                     NVQWIVMKQTIEMSKKQIKVFHKLFPTNNRPVQPINGRAVL"
     misc_feature    complement(21640..21655)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.35"
                     /tool="antismash"
     misc_feature    21657..21670
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     misc_feature    complement(21662..21675)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     CDS             21807..21923
                     /gene="allorf_091984_092100"
                     /locus_tag="allorf_091984_092100"
                     /protein_id="allorf_091984_092100"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDLPSINIKLKNNPNIKRLNSQDENVQFCFKCVIKFLS"
     CDS_motif       21807..21893
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDLPSINIKLKNNPNIKRLNSQDENVQFC"
                     /locus_tag="allorf_091984_092100_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21894..21923
                     /prepeptide="core"
                     /locus_tag="allorf_091984_092100_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="1066.4"
                     /monoisotopic_mass="1065.6"
                     /core_sequence="FKCVIKFLS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLPSINIKLKNNPNIKRLNSQDENVQFC"
                     /leader_location="[21806:21893](+)"
     misc_feature    21866..21880
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.7"
                     /tool="antismash"
     CDS             complement(21946..22131)
                     /gene="allorf_092123_092308"
                     /locus_tag="allorf_092123_092308"
                     /protein_id="allorf_092123_092308"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSIIHLIIRLNLQSFLFGWRYFRLLFLCIMSLALNIKYHKTKNHK
                     ILTNSTFFSQTNITTN"
     CDS_motif       complement(22078..22131)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSIIHLIIRLNLQSFLFG"
                     /locus_tag="allorf_092123_092308_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21946..22077)
                     /prepeptide="core"
                     /locus_tag="allorf_092123_092308_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="5059.9"
                     /monoisotopic_mass="5056.8"
                     /core_sequence="WRYFRLLFLCIMSLALNIKYHKTKNHKILTNSTFFSQTNITTN
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSIIHLIIRLNLQSFLFG"
                     /leader_location="[22077:22131](-)"
                     /alternative_weights="5077.9"
                     /alternative_weights="5096.0"
                     /alternative_weights="5114.0"
                     /alternative_weights="5132.0"
                     /alternative_weights="5150.0"
                     /alternative_weights="5168.0"
                     /alternative_weights="5186.1"
                     /alternative_weights="5204.1"
     misc_feature    complement(21969..21984)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 26.0"
                     /tool="antismash"
     misc_feature    complement(22629..22644)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.5"
                     /tool="antismash"
ORIGIN
        1 agtagtgaaa tatttatttg gaatgtgtgg gtatctttaa gcgaagaaag cttcaataaa
       61 acaatggaat tatgggaaac aaaaggaaga gaaacagaag atccccattt cggatggctt
      121 tctacatcaa ttccaggtta tcctgataca ttaaatttaa aaacaaatgt ccatataaga
      181 gccattggaa taagaccctt tattgaattg gaaccgactg atcatccctt agcagttgaa
      241 cagagagaag gaattactct agaaaaagtt gcagaaatta aagaaattgt tactcaatat
      301 aatcaagaag aggattctga gtaaaacata ttacaacttc caataacggt gattatgtga
      361 acttcagatc agattggtat ttaataaaag aaattttata agttgattga acatctaaaa
      421 ggagtatggg ggattttgag aaaaactaaa ctgagaaact atgtgaaatt atttattctc
      481 tacttaatta taatttcaat atatttccta ttgtttgatt acagtaaagt gtatattaag
      541 acaaaaataa ataacgaatt tttatatcaa ttatatttat taataggacg tattagtatg
      601 ggtttgggaa tatattttat tccagataag ctaggtatta agattaaatt cagatttaaa
      661 tttcttatag cagttatcgc aatgataact actataattt ttcttgatat agttggttta
      721 atggaataac tttgataact tcatataact aatattaatc aactcccaat aacgaaaatt
      781 atgtaaataa gctgtccata tggacggttc tggtgcaaaa acttcaaggt aattacaagc
      841 aatctctaaa acttggacat actgatacta ttactctaaa aaggtgtgtg atcggtatgg
      901 gaaagaaaat tggttcaaat ggaagcaata tcagcctgat attattttat taacggtaag
      961 atggtaccta cggtacaacc taagttttcg tgatttggtg gaaatgatgg aggaacgggg
     1021 tttatccatt tctcatacaa cgattatacg ttgggttcat cagtatggtc ctgaattgga
     1081 caaacggatg cgacgttacc tcaaaccaat aaatgactct tggagagtcg atgaaacata
     1141 tatcaaagta aaaggtcaat ggatgtacct gtatcgtgct gttgattcga acggaaacac
     1201 aatcgatttt tgcctaagca aaacaagaga tcataaggct gcaaagcgct ttttcaagaa
     1261 agctttgcgg tcttttcatg tttcaaagcc acgtgttata acagtcgata agaatccagc
     1321 ttatccgata gcaattgaac agttaaaaaa agaaaaaagc atacctagcg gtatgcgact
     1381 tagacaacaa aagtacttga ataacatagt agaacaagat catcgcttta taaagaagtg
     1441 aatccgttct atgctaggtc ttaaatcttt tgaaacagct acatccattc tttctggagt
     1501 agaagccatg catatgatta aaaaagaaca gattgcttta cggaactagt ctgtccaaaa
     1561 tcaaaaagaa ttcatccatc aattgtttgg acttgcaata taagatacga ttccgttagg
     1621 aatatatgtg ctttattctc ttttgtttta tttttgcacc agaaccataa aaaccatata
     1681 gatctagtta ctctaactga tataataaat atggaaatta ttagttaatt agtattgcct
     1741 atattagggg gataacaacg atgagcaatg acaagtataa gggcatgcca tataaacaga
     1801 tcaaagagga atcaagaaag aagaacgcgg gttgaacgcc tatggaaaga tgagtataca
     1861 acaaggctgt acagtttggg cattaatcct attgtttgga ggtttcattg tatggttgtt
     1921 cgctggtagc agcagtagtt atgatagtaa taaaggcgct aataatcctt atatgaacga
     1981 taagaagcgc gaacaaatta acgtaatgta caatttcaag aatgaaatcg aagtataatt
     2041 aggttataag gctctcacat caattgtgag gactttttct attataggta taaatctatt
     2101 agttgagtta tagaaacgct tatacgtggt attaaaattt agtggtaata gcaatataat
     2161 acctttatac aggctgtcag ttgtaatcta attaataagt tctatataaa atgatatatg
     2221 atgttccttt ctaaaataaa tccatttatc tttataaaac gttatatgtt ttataaagat
     2281 aagacaccct aaggtgtctc actgcgactt gaaccatcgt aatatggtat cggatgccaa
     2341 tccaaatatt attttaccac gttaattagt tttatatatt gagaaatatg acttagattt
     2401 atagtttatc taaaagcatc catctgcact tcttcataaa taaacttagt ttctttggct
     2461 gtaatcccaa aacgtttagc ggctatttca gcaacctgag gatcatgtac ttcagggatg
     2521 tagttttcat tgctatttgt aaggatgttg tattgttgtt tcataaagtc gaatataacc
     2581 gtatggctta tttcattact tgtatattgt ccattcggtg aagaaggaac gggagtaatt
     2641 aagaacgcta tggggaatgg ctgctatcaa tttgcaccat gtatttgcga agctgggaat
     2701 cacagccctg aagaagtgga gagaagacgt catggcgtta tggcggagct aagagaaagt
     2761 catcaattac aactggaggg gaaatgagat gccaggactt ggaagggatt tggagaagga
     2821 gaattacaca atgacgttac agcagggatg gtacatgaag aaattgcgtc gtaacttata
     2881 tattgtttta gaagagttgg acttagtgtt taatgaaagt gaagtgatgc aattacgaaa
     2941 aatgtgggat taggataaag atattcttaa aatagcaaag gagctaggaa ggtatcaatt
     3001 agaaattgcc gcattaatta tggatcaggc agataagaac aaaatcaaat cctgtccaat
     3061 ggggttaggg ggatgaagcg actaacactg gagggtgtag tcggaagttt tgattatacc
     3121 gaaacaagta ccgtggacaa attcttgaag cgtaatagcg ttatgacgta ctcagtagag
     3181 ttttacgaaa aagacgaaaa gtggaaactt cgtcggtttg aggcgaagtc cgagagcgaa
     3241 gctatagaaa tggctaaaga gaaatacgga aagatagaaa ttattactac ttatatttcg
     3301 gatagaactt tagaagggat aatacatttt gattaggaga catagcgtta tgacgcgtga
     3361 taattggaac tgtggatagt ggttttagag gagaagttgg tgtgctaaat agttttggaa
     3421 gtagggggat taaataaaaa aggctaggat ttgttcctag caaagagtta tgacgtacag
     3481 aaaggtacaa gcctgattgt ttgtgatttg attatataac gtttctaggg tggaaggatt
     3541 gaatcatagc aatctttacg taacttttac atgtaattga agtatttgat taagacgaaa
     3601 tttgaatttt gtagaaccgc agaatgagga aatatgaata gagtattagc gaaacccaac
     3661 cttaatcaac tcttcattgt ttatttcaat tacgaatcta tattctttat ctaatagcca
     3721 gtaataaaaa ctgaccgcat caacgtcaac tagtgattgg aatactttat caagatttgt
     3781 acttactaca gggatttcat agttatccca tattataaaa atctgttcat caaaatctag
     3841 ttggtgtgct ctaataaggg aaattagttg ttttttgttc gaagctatta attgagtgtc
     3901 tatctgttcc caatcaattc ttcctgagac agttatagga aataaattca ttaaagtagt
     3961 agcaatctgc tggctttttt cttgagagga aatgagagtt tcgtttccta gagactcaag
     4021 gcattcatta aacaaagggt ttgtatcact tctgtttttt gttttcagtt ctcttaactt
     4081 ttgtctcatt ttccattgtc ttgacgatct atcatccatt tttaacattc cttatacaat
     4141 tatttatgaa tgagtatagc atataaggga agttcttatg aaaatgaatt tttataatat
     4201 aaattaaaca aaagcgttat tttatagcaa tgtgaaaaga gcacacagca aatgtgtatt
     4261 cataacaatc taaattattt taaggaccat aatatatcat taagaacctt ataaatataa
     4321 ctatacatac ggtaaaagag atattttgga ttgtattttt ggttccattt cataaaaatc
     4381 accccttata caaatagttt aattatatta tacagttatt aatttgaata ttaataaaaa
     4441 tcattattaa ttaaggtaaa tttaaacaaa gtagttataa aaaaaagacc tcttacggaa
     4501 agataagaga tcatcaaaaa atgttgtatt tgaaacacgt gatgtttcaa aaaggtatta
     4561 taaaataaat atctatatat aatgtatata caattttaat aatgggtgga aataataaag
     4621 ttcataaatt ccttattaaa aaaagaaacc ctaggattag ggggctaggg ctttctgtgt
     4681 tggtatatct cacacgatat tataaaaaga aaagaacgta ttgaagataa cacatgaatg
     4741 tttcataaat gtatcaaaaa agtgaacaaa aaagatattt taattgtctt agccccttgg
     4801 agggcgctcc aaggggctaa gattcgagaa tttttaaact cctgtttaat tatatgagaa
     4861 ctccctaagg agtacatatg gaattttaac acttaactga tcatttttac aactgtatat
     4921 taagattttt atataaacgt taatgaaaaa aaggaccatt tagatggaaa ttcagaatat
     4981 agtttgccat taaattaaaa aattacaaac aaattccgca aaacatctgt tcggcggaat
     5041 ttgtttgtaa tgataaatta tatatatctt ataacaacta taaaatattt tatataatta
     5101 taacgattat aaaaatgcaa attttatata aggtctatgt tgattaattg attaaccgcg
     5161 taatccacat ctagtagtac atttagatgt tggacaaaat gcagcagtaa ttacaactgc
     5221 tagttcacca caagggatag ttgttccgcc agataaatca ggtgattcag ttattttttt
     5281 ttgtaattat taccagcacg ctgggcgaca ttctactgat agagtacacg tactaccgtc
     5341 atttccaaga tggcatgata aatcccacca agtgcagtca gcaccgaaag aattttcaag
     5401 acgcttatcg ctcttatcta gttggttcaa gtagctttct tttgctaatt cagaaatatt
     5461 ttcttttttt agtttgaaca tttttccatt aacacctcct aacataaacc ttatatgtaa
     5521 atataatata atatctggat aaaatatgct atagttaaat tgaaatttat ctaaaaatag
     5581 gatgattcat aaggagagag ttatagagaa aaacttttat gatttagtag ttaagtgtat
     5641 agcgacctat ttagaagata aggaaattaa attcgttaat atcactttat aataaattgg
     5701 aggttgaaaa acaattagag gacacactaa tcgataatct ctatccatta gtagaagata
     5761 gttttttaat tgcttttcag ttatggaaag aaaagggggt tagcccgaag gagagtagta
     5821 taaatacata ctacgaattg attagcgagg aatttataga tggttgttct ctcgatttaa
     5881 agaattagag catatgctta ataagtgtgt tatatatctt gagaaataca taaataaaat
     5941 tttagtagat ttagaaacat ttaaaaatgg tttttatttt acagatttga aaagtatctc
     6001 tttagatgct ggcgatagtc atgcagaagg taagtcggtc tgtattatta atctagatga
     6061 tacttgctat atttataaac cccgaatgac tgagttagat caacgtttta tgaagctaat
     6121 ccagtctcaa ataagagagt acaactttac tatttattca tatgataccc tttcaattca
     6181 tgagctaatt gtatataaat ctcctgaaag tatagaagat attgaaaaat attatttata
     6241 atattggtgt aatttcagtg gttatgtgta aatttaaata tacggatatg aattatgaaa
     6301 atgtaattgt ctcaaatcga gttccatttt ttgtggactt agagacataa acgattcaag
     6361 gaagaaaatc caacgcttgc tttttggatt ttgctactga ttcagtactt gatacgatga
     6421 tgtatcctat atatgaggga aagtgatttg aatgtatccg ctttaactgg tggggaagct
     6481 gtttataatg atttttatta taagcagaaa gtacttgtgg attataataa tgattctgtt
     6541 aggtatgaag aggctccaat tgcattagaa gacaaaccga ataggattta aatcaatggc
     6601 agaaaaaatg tgggaaaata aaaaataatt tacaaataca tttctggaag tcattgaggg
     6661 gaattttgta cgccaggtgt tacgaccgac tcatgtttaa gcaaagtttt taactacatc
     6721 atatgaagca tactatatac agaaagatac atatagggaa gaattatgta acactcttct
     6781 aagtaacaat gaaaatgacg ataagcagaa agcaattgca gaagaaaaag taggtaactt
     6841 gctaaatgtt gatattccta tattttatgt ttattttaat gattgatatt tatataacca
     6901 taaaggagaa atagcctgtg aagattattt ttttgagttc atctaaacgt atggtaatta
     6961 atggaatcta gggatgttca gaataagaaa taaataggaa aatttatcat attgaatcca
     7021 gtttatttat ttctgcatat aataagagtg atgatccagt actatctcaa agccaatcaa
     7081 gtaaggatac gtatggggaa gcgcaagtga tatcagattt gaaggaattc tcagagttga
     7141 ttgtagatag aggtagttac tttgtatgtc gaagaaaaaa ataattattt agatcctaga
     7201 gataatgtac ttactaataa ttattattgc tatggtttat cagggatttt attatccgaa
     7261 atttaactta taaaaatagg tgaatgtctt gatattgaag gtctaaataa aaagttaata
     7321 agtttatgca gcgcgataat aaataatgaa ttagaacttg ataaattggg ttattgctta
     7381 tgtcatggga taggtagttt tatggaattt atagaagaag cttataaaga gggtttgata
     7441 tctcataacc tctatataga agtacaaaca attttaatgg aaaagttaaa tagtaatacc
     7501 aatagtttgt tgacatctaa taatctgtat ggctttatga tgggaaaagg aagcaaggta
     7561 tatagttatc ttagatatgt tattacttag tattaattag tagctgtagc tactcagtta
     7621 ctccatgtga ataagagata ggtagggaaa atatctcgaa aaacagtttg ttctcgctgt
     7681 tttttagtag gaatggttaa taaaggtaca tttttcacta aaataatagt gagaatatct
     7741 atatgaatcc tactaatctc tgaaaaacag gatgtatctg agtagttaca aataattaat
     7801 ccatgattat ataatatctc ggtgtataga tgtaatatga ataagttgtt gaaggaggag
     7861 aaagtttgag aaaaaaggtt ccatatgttg gacaagttca agaatcagaa tgtggtttat
     7921 gctgtgtttc tatgttgatg ggttattata agcaatttat tccagttaaa acgctatcca
     7981 aaacgataga ggttggtcga gatggtgttc atataaaaaa actgggtgag gttttagatt
     8041 cttttgggta caatgtttcg tattatgaag cagattcaaa tagtttaatt caaatcgcag
     8101 ataaaccttt aattttattt tggaataaaa atcattatgt tgttttggaa aagattaaaa
     8161 atggtatgtt ttacattgta gatcctaact ttggaagagg gaaattaacg ttagaggaat
     8221 ttaatgaaca tttcagtaat atagttttgc ttgcagatcc cacggaggca acaaaaaaaa
     8281 taaatttaaa agaaaatccg tttaaaatgt acattaatta ttttaagggg aaatattggg
     8341 atctaattgc ccttttaata tgttctattt tatcaactgc gacagtttta cttgtgtcta
     8401 tttttatgaa aaacctcatc gaccgtacta cagcttcaag taattctata ctaaatagta
     8461 acatggtaat aggacttttg ggtttaatga ttatgttttt agttttcgat cttttaaaaa
     8521 gtaatttagt aattatattt tcggctaaat tagataaaag tatttatacg agtgtagtca
     8581 ataagctctt ccgtgtacct tataaatttt atcttactag gagttctagt gatatattat
     8641 ttagacttag tttattaaaa tcaaacagaa atttttttat cgaaacatta attaaaagca
     8701 ttttagatgt gggtatgcta gtatttgttt tgatttttat gctgtttatc gatccaatac
     8761 tttgtgtatc tttaattatt attagtattt tattagggtt atttttatac ttcattcgta
     8821 aactgattat cctaaaaaat aaagaagaaa ttattgaggg aactaaacta caggggaaag
     8881 aatatgagac actccttgct atatcttatt taaaatctac tggacaagaa gaatatataa
     8941 aatcattgct gttaaatcag tatgatgtag ctttaaataa gtataaagaa aaaagtttta
     9001 ttgataatat atatggtaat attacaaaat tcgtttctta ttttgctcca ttattaatgt
     9061 tctttttagt attatctttg tatcaacaat ccattctttc attaggtaca gtaatgcttg
     9121 tgtattctat atcaaattat tattttacta gtttaaacgg agtgtatagt agctttaatg
     9181 tgtatggtac acttcaaaat aatcttgaaa ggattgtaga tatattagaa gaacaagagg
     9241 atcattactt tataaaagag gggacgatta cagttgatga aattaaaaca atttctttcg
     9301 ataacgtatc atttagatat ccaggtcaaa cagattacgt tataaacaat ttaacgttta
     9361 cagttaataa aggagaaaaa gttgctatag ttggggaaac tggttctgga aaatcaacta
     9421 ttacaggatt attattagga ttatttattc ccgagaaggg aactataaag ataaatggta
     9481 tcaatattga ggatgttaat agagaatctt tgaaaagttt actaggttat gtcccgcaat
     9541 cacctaatat ctttaataag tctattaaag aaaatatttt gatgaataga gatataaatg
     9601 aaaagcaatt aatagtatct gccgaaagag ctagcataag taatgatatt gaaaaaatgc
     9661 cgatgaaata tgagactgtt atttcagaaa tgggaagtaa tttatctggt ggacaaaagc
     9721 aaagaatagt cttggctagg gcaattattg ataatccgga cttacttatt cttgatgaag
     9781 cgactagtgc tgtagataat gtaacagaag ctttcatatc tcaattttta caacaagcta
     9841 atatgacaca aataattata gctcatcgtt taggtactat tattgaagct gataaagtta
     9901 ttgtattgca agaaggggaa ataacaaata ttggaactca ttctgagtta ttaaacagaa
     9961 gtgatttata taagcagatg tatgataggg agttgaattc atgaaaacaa tagattctac
    10021 aaatcttata agtgctgtag tacatatgca agacaattca ttaaagtggt taagtaagaa
    10081 acataaattc tcatttgttt ggacaaatat tgttgaatat cttgtatcta ataaacatga
    10141 tctttcgcat aaagaaatga aaatatttaa gggtaacata aattctttat atagttcttg
    10201 tatgtcgcta gtaacgccaa ctatgatctt tcatctaaac actctttacc aacaaaatca
    10261 agaaaatata gaggtagatt ttcaaacctt ttataaagaa tttcaagata cttttattag
    10321 tgattataca cttagggaag atgtttttag tacgtatccg gaactttttc gattaattta
    10381 taatttcttc gatcaatcaa tttataatat aaaagaaagt atatacttgg tagatgtgca
    10441 ccgtgaagag ttaaagaaca gattcaatat tgaagaattt gatgaattat ccataatctt
    10501 aggtgaagga gatgttcata aggcgggaaa aagtacatcc agagttagta taggtggaaa
    10561 aacactcttt ttaaaatgga gagagtgctc ttttgaaaag gatttcattc agtttcagca
    10621 caaatttctg aaaaacatgg ggattaccaa tagaataaat aatttaaaag aagttgaggg
    10681 aagcaattat tattttcaag aatccattga acccgaaggc atttttgaag aggaacataa
    10741 tgagcattac tatcaactgg gggcttttat ttttatagct tacttaatgg gggttacgga
    10801 tttacattat gaaaacatca ttatagctaa tgggaacatc attgctattg actgtgaaac
    10861 aatcgcaacg tctaaagagc gtgaaatgcc agaatatata gattacgatt tagcgaaatc
    10921 tgtatattct acattcattt taccatttaa tactgtaaag ggtgctgtgc tatcaggaat
    10981 aagctcactt tctagtcaaa ctatgtatgt taatgattat aaaataaaaa ttactaatag
    11041 aggtattgat ttagctaatc gtccattgag aacaatctcg aaccctaata gtgaaaaaga
    11101 taaatctcct tattttttac ataccaatga aatagtgaaa ggctttgaag aatcgtatat
    11161 tgaatttttg gaaaataaaa atcaatatat agatttattg caaacgatgt tggctaacaa
    11221 gaaacatagg gtattaaaga aaaacactta tgattatagc gcactgttat gggaaagtta
    11281 ccatccgtat ttaatgacga gttatgaaga aagatatgga ttttttgaaa aaaattcatt
    11341 attggataat gatgaacaaa tcttacttta taatggagaa atcccttata ttgaggaact
    11401 tattaatatt caagagaagt attttgatag gttttcttat gatgacttaa agagacagac
    11461 ggtattgata aaagaatcac tagaatttga taaggtgatg tacttaacgt caaatgagaa
    11521 aaataattta ttagtggaac ctactattgg ggattgtgaa atagataaat ataaagatta
    11581 tcttttgtca aatagtgttg ttgataattg gataacttcc attgaaacgg gtgttacgca
    11641 tgaggatacc gaatataaag aaatagaact taacataatg ccggatacat tatatctagg
    11701 gaaatccggt gttattaaat ttttatgggc atattacgat cgaaaaccga ataagcaaga
    11761 agaaatatgg ttcaagaatg tgctcaagtc attttggatt aaattaaaga agcatattat
    11821 aacaaatcct aaaatacaaa ctggattcta tgatggtata ggtggattac ttcatactat
    11881 gtattttgca aataaaaggt atagtatatt tcatgataaa gaattaatac aaatacttat
    11941 ggtaataaaa aagaatattt catatgatac tcaatttgat gttatttcag gaagtgcagg
    12001 gttgttgaat gcactaatag atatgtatca tgatagcggt agtgaggatt tgaaaaaaca
    12061 actactcgat tgcattactg gtgctgaaac ccatctaatt attcattttg atgatataaa
    12121 ctgtggatgg tcattcgaaa atccttctga tcctaatgat atattttatt attatggata
    12181 ctcacacgga ttatcgggga taatccctca attatacaga agctttttga ttacaaataa
    12241 tgatgaaata aaacaaatag ttgataaatc agtaaaaaaa atgattatgt tatatgacaa
    12301 tttcgaaaga aattggccta catctagctc agtagacacg tattatacta attggtgtca
    12361 tggttcgcca ggagtaattt atggattggg aattttattg aaaaatggat atgtatctaa
    12421 ggaaataaat aatatcatct acgaagtttt attgagatta gtgagagaag aaaaaccaaa
    12481 tctttgtcta tgtcatgggt cctatggaaa tgatataatt ggaaaatatt gttctgaaat
    12541 aattgagaat aataaattaa aaacagcttt tgaaagaaaa ttagatgata attggttaaa
    12601 acttttaaac acggataata tcattaaagt aaataaatct tatatgacag gaataacagg
    12661 aatatattat tggaaattga ataataacaa tttggatcac atactttgat gagatatagc
    12721 tagtgatagg tggcaatatt ttgagggaaa gggaatttac aataaaatat tttggatgcg
    12781 atttccgatt acttgaagtg atgcagttaa ctataaaaat agtttatttg tttaaaaaat
    12841 tgtaagaatt aagaagtata ttagattaag gttcaatacc gtgaggagta aaaggtagag
    12901 caaatagaag ctctaccttt tttagtttgt ccagcacggg taaactctat aggggggaag
    12961 ttctgacctt ttctctgtat tttgtataag tgaattattt atattcctgt cggttctggt
    13021 gcaaaaataa aacaaaagag aataaagcac atatattcct aacggaatcg tatcttatat
    13081 tgcaagtcca aacaattgat ggatgaattc tttttgattt tggacagact ggttccgtaa
    13141 agcaatctgt tcttttttaa tcatatgcat ggcttctact ccagaaagaa tggatgtatc
    13201 tgtttcaaaa gatttaagac ctagcataga acggattggc ttctttataa agcgatgatc
    13261 ttgttctact atgttattca agtacttttg ttgtctaagt cgcataccgt taggtatgct
    13321 tttttctttt tttaactgtt caattgctat cggataagct ggattcttat cgactgttat
    13381 aacacgtggc tttgaaacat gaaaagaccg caaagctttc ttgaaaaagc gctttgcagc
    13441 cttatgatct cttgttttgc ttaggcaaaa atcgattgtg tttccgttcg aatcaacagc
    13501 acgatacagg tacatccatt gaccttttac tttgatatat gtttcatcga ctctccaaga
    13561 gtcatttatt ggtttgaggt aacgtcgcat ccgtttgtcc aattcaggac catactgatg
    13621 aacccaacgt ataattgttg tatgagaaat ggataaaccc cgttcctcca tcatttccac
    13681 caaatcacga aaacttaggt tgtaccgtag gtaccatttt accgttaata aaataatatc
    13741 aggctgatat tgcttccatt tgaaccaatt tttctttccc atatcgatca cacacctttt
    13801 tagagtaata gtatcagtat gtccaagttt tagagattgc ttgtaattac cttgaagttt
    13861 ttgcaccaga acctaaattt ccttaaacgg ttgtttttgt cacttgagtg tttacatgaa
    13921 ttcactaagt atatcatctt ccatttgtta tggttttcaa aataactatt tacatataat
    13981 tcacattagt gtactgtttt tctagtacac taatgcagag gaggaaagaa atgaaaacgg
    14041 agttttctcc taatgtccct atttatgttc aggtaatgga atacatcaaa aaagaaattg
    14101 taacaggacg tttggcgcca ggtaaaaaaa ttcctgctgt acgtgaatta gcgggtgaat
    14161 tacaagtgaa tccaaataca attcaacgta cgtttcaaga gctagaacgg gaaggtatta
    14221 ctgagacacg tagaggaaca ggaagatttg taacaatgaa tgaagaaaaa attacagatt
    14281 tgcgcaaaga tatggcaaaa gagttgcttg ataattttat aaatggaatg cataacttag
    14341 gatttatgga agaagaggtt ctctcaatac tccgttcttc tttggaaaag aaaaaggaag
    14401 gaaatgaatg aaagaattat taaaagttga aaatctttcg aaaagatatg atttaaaaac
    14461 agtgattcaa gatgtaagcc taacaatctc agaaggaaaa attatcggtc ttgttggtga
    14521 aaagggtagt gggaaaacga cattattaaa aatgatttcg tgtttacgtt ttccttctac
    14581 aggaagtatt acaattaaag ataaaaaggt gggattagaa acgaaaaaaa tcgtttcatt
    14641 tatgcccgat agtcctgttt ttgaaaaatg gatgaccgta aaagatgctt tggtgttcta
    14701 tcgagatatg tatgctgatt ttaatctaca acaagcacta gatttaatag ctaactttaa
    14761 aatcccgcta gaggggaata taagcatctt atcaaaaggg aaaacaggga tattacagct
    14821 aatattaact ttttcaagga aagcaacggt atatgtatta gacgagccat taggtggaat
    14881 tgatcttgtt tctagaaagc atatagtaga tttaattctt aacttttatc gtgaagatag
    14941 taccattctt atttcgactc atttaatagg ggaaattgaa aatatatttg atgaggtaat
    15001 ctttttaaaa gacgggagta ttgtattgca tgaaaatgta gaagaaattc gttttcacca
    15061 tggaaaagca gtacatgagt tatttaagga ggtttttgag acatgaatcc actttttcgc
    15121 tatttattta attgtaatgg aaaaaagata gccatccttt attttggatt tattactatt
    15181 ttgtttacct ctttatctac caaagataat ccctctagta gatttggctg gacccctttg
    15241 gaccaggaca ttaattttgg ataattcttt gtttcaaaca agtttgaaat aagcatattt
    15301 ctatttgttt tattaatgat atccttaatt ttattagtcc ggataccatt aaatgtgttt
    15361 ttttgttttg tgtatctttg aaccaaactt tcattactaa atttaggtag taaccatcgc
    15421 cacacatctt taccagacat atattccctt cattctaagc gtacacgatt atctcccctt
    15481 tcaagaaatt gaataaaatg tacaacaaat atattgtatt aaaaaatata aaaatataaa
    15541 gatgaagcat tttagttttc caaccattta gtttgtaatt ttctgatttt cacaacctaa
    15601 atgattgagg taatcttttt ttgtttcaaa aggtacacct tttggaaatg cgaaaaacta
    15661 ttgaagaaca cacgccaaaa ggtgcaaaaa acacttttgg gacacttcag aacaaaaatg
    15721 taccttttgg tgtatttttg caccagaacc acaaaaagtt aatttcgtga taattctcaa
    15781 ttttaagttg atggatatag attattaact taaaacatca taatttcaat ggtctaaagg
    15841 caacagcctt tcattaatat aacaaatgga aggttattta attccctatt tttggatatg
    15901 cgaaattgca taaaaaaaca tgtttaaata agacgcgctt ttatatataa ctagaggtag
    15961 agaaggaaaa ttactgttta aggttaattt aaaattttta atttaatcga tgtgtggttg
    16021 tattccttta agagagaaat taagcagtta gcctttgcta atcgctcttt tattagagct
    16081 atttaactgt cgttgttaag atgaatatcc gcataagaat ctttatattt aggaaggaat
    16141 aaaaaatgaa aaaaatcgta tcaacactat gtatagctgg agtgacttta actattttag
    16201 gagcatgtcc tcaaagtagt tatgctcatc tcgatcaaat tgatttaaat gagaatgatc
    16261 ctattactgc aagatggtct gcagaagctc cgtatcattc tgataaaagt acacatttat
    16321 ggattgcaaa acaagctatt gaaattatga aaacagaatc taatattgaa gcaaataagc
    16381 aggcagtgga ctttttaaat tatccacaat ataaagatct attttctaaa ggattatatg
    16441 atgcagatta taatgcagag tttaatgatg gtggaacagg aataggcggc gtttttaaag
    16501 gcggatggaa atctcatttt tatgatcctg atactaaaga aaattataga ggagaaacaa
    16561 atccaaccgc ccttacacaa ggtaagaaat acttttatga atctggagaa cacttacgaa
    16621 ataaggacta tgaaaaagct ttctattact taggagtagc tacgcactac tttacagatg
    16681 ctacccaacc tatgcatgca gcaaatttta ctgcaattga tacgagagct ataaaatatc
    16741 atagctactt tgaaaattat gttacaacca ttcaaaatca atttgcagtc aatactggag
    16801 ggaattataa caattcccta tccacacctg aagaatggat tgattatgca gccagagtag
    16861 ctaaacctga aatccaaaat attactaatg ataaaacatt taagtattat aatagtggta
    16921 aggcacaatt gtggcaagaa atggtaaccc cagctgtgca gcggagctta ggagaagctc
    16981 agcgcaatac agcaggtttc ttaaatctgt ggtttaaaac ttttactgaa aatgtgaaag
    17041 ctccaagtat agagactgca ttaatctatg atatagaagg aaacgtcata gaagcaggga
    17101 aaaactatta tatcgtacca agtgaatctc cttatcaagg tctaacattt gaatggtata
    17161 tagcaaatcg ttacgattat gtaacacttg caaataaaga aaacaatggt ttatctggta
    17221 cacctatgga atttgaattc tacaaagaaa atgatgcaaa gctacaccac ggggagagta
    17281 tatatcttcg tatgaagcac tcaaattacg accaattcca atatttaaat tggtctaatt
    17341 attctagttg gattcacctt gctcaaaaat ccgatagttt agctgatttt aaaattaaaa
    17401 ttaacctgga taatcctaca gaatataata tttttacaga tgactatcca ttaaattatg
    17461 aaaatataaa tgcaaagaaa aattggattg tactaggtga aaaaacacaa aaacctagct
    17521 cgtggaagtt tatccctgtt agataaccta aaaagaaaaa cactcgtcct taatgagaac
    17581 gagtgttttt ttattccgta taataattta aatcaatagt tatatcacaa taaactggtg
    17641 aaaacatata taaaggtata tagaaaaaaa tgagatactt cctaaaaagg ataccgaaag
    17701 gaaattaaca aaaacaatag atggtatacg gtttgaacta cccccacttt cacttcgttt
    17761 agaagagggg gattcctaag taaagagttc tatcgaactc taatttatta ggctatctcc
    17821 gcagtccttg cggttagaag ccttatcgct tcattcttta gattgatact tgcgttaata
    17881 tccctatcat ggtgtgtacg acaagaaggg cagtcccatt tacgtaggtt tagattttta
    17941 acgtctttgt tttgatatcc acaacaagaa cataattggc tggaagcaaa tgttttcgat
    18001 acgacaatga tttgtttgcc gtaccatttt gccttatatt ccaacatagt tcgaaattgt
    18061 gaccatgata cctcactaat tgcttttgct aacttatgat tctttaacat attcgatact
    18121 tgcaaatcct ctataccaat aacatcgtgg tttttgatga tttcagtcga gattttgtcc
    18181 aagtaatctt ttctagcatt cgtcatgtat tcatgaattc tagctacttt tactcgttgt
    18241 ttattccagc gagaagatcc tttcattctt ctagaaagaa cacgctgtgc ttttgccaac
    18301 ttttcttcta atgatcgaaa aaacttcgga tttttatagg ttgttccatc tgataatatg
    18361 gcgaaatctt ttagtcccac atccattcca atgtaagaat gtgttttcgg aagttcttgc
    18421 acttctgttt cgactaacaa tgacacaaag tgtctgccag aagggttccg tctaactgta
    18481 gcatttacaa tacgtcccgt tatttcacga cttttagcaa atcgaacaag acctagtttt
    18541 ggcaatttta ttttgtttcc tacaacggca atgttttcat ttgtttgttt tgtggtgtaa
    18601 gattgtacgt tgttcttctt agatttgaaa cgcggggcat tgttttgttt tttgaaaaag
    18661 cgtgtataag catccgcaag gttgcgaaca gacgactgaa tcgcaatact atccacttct
    18721 tttagccaaa caaactcttt cttcatggca ggaagtttgg cagagcatgt cccatatgtc
    18781 aaaccttttc ctgtttcttt gtatgcatga tcccatagag ataggaaatg attgaataca
    18841 aaacgagaac agccaatcgt tttattgatt agggtcgctt gtgcttgatt tggatagata
    18901 cgaaatttat atgctttatt gatcatcatt cgtttcaccc ccatttcgat atgtgtctat
    18961 tatacaacaa acgtatattc gataggtagt gaagtaacag tttatgtatg tcgaacaatt
    19021 aagatggctt cctgccatcc cttgtccgaa gccaattcat ctcccaccta ctcacttcgc
    19081 gttccttgag gaaggagtct tcttggctaa aatgataaat aatattttgc actgtgcgat
    19141 tgctgaaaat aagagagtat gtatttctta tcaaatacaa agcatgttcc gaatggggga
    19201 attatgactc aatgtcagaa aagtaacaat tttgttactt tttgttgata tatgtcgatt
    19261 ttaatgttat atttataaca acaaagaaag agtaaacaaa aaacccttat ctagtaatgt
    19321 ttcagaattt ttagttttct ctacctatgt acttcttgtg tcgaagaagt ttgtgcattt
    19381 ttttccactc tttctttgtt caccctacat aagaaagcaa tctgttttta tacaggttgt
    19441 ttttttgcgt tataacgtcc agcaaaaaca tggagtggct ttgcaatatg ttttgtaatt
    19501 aaacttgtag tttacttcaa ttacggttaa aaaataatac cttacaaaag ggacaaaagg
    19561 aaaatgcagt ataatgaaaa ggctgttgtc ctattaggac agcagttttt gtcgtactgg
    19621 tacaaaaaat aatatgactg tctatactga aagtaatgaa aaaattacgt cacttttttc
    19681 attattagga tatggtttgt aaggggttat aattaaatgc cgaaaaagta acaattatgt
    19741 taccttttgt tgatatatgc ctttttgatg ctatattcat aataacaaag aaagagtaaa
    19801 cagaaaccct aactagtatt atatcagaat tcttagttct atctaatcga tctacttttt
    19861 gtgctgtata agtttgtgtc ttttttgcca ttctttcttt gttttaccct taaaagaaaa
    19921 caatctgttt tatacaggtt gttttctttt gtaaaaatat aatttatttt attattttaa
    19981 ggtatttgtt taagcaagac atgtactatg aattataatg ttcaatgttc aatgttcaat
    20041 gttcaatgtt cattgtttat ttattctata attattatat aataattata gggttttatt
    20101 ttaaaaagag atttttgcta atgatttata tatctagtat gttatctttt tcttttttaa
    20161 ggaacaaaaa gatgatgtag cataatggaa aagctgctgt cctaaaggga caacggcttt
    20221 ttctatactg gggcaaaaaa attaataatt tcattgagca agagaatcat tatttaaatt
    20281 gtctgggttt caaaacttcg ctatgattct cgtataataa acattcataa atcggtaata
    20341 tagatcaaag tattggttcg cactactgat ttctataata ctgctcgtcc attaattggt
    20401 tgaactggtc ggttattcgt tgggaataat ttatggaaca ctttaatttg ttttttggac
    20461 atctctattg tctgtttcat cacaatccat tggacatttt cagtacaagg aggtgttgtc
    20521 aaagacccca tgtaacggaa tgatgaatga tctgaaggaa gaatctgttt tatatcaatg
    20581 gtatgttgca catcggcctt tatgtttttt ctgtgcggga gattttgcca cattgctgca
    20641 aaaccttcgt ttttttgtcc ttcttttatc ataataccta ctactgctaa ctgaccttga
    20701 tcattttgat ggactagatg taattccata tctgcatgtt ttccttcaaa ttggtgctca
    20761 cttggtgtat gaaaatggaa ttgttttaat gtgtaacgat tttctcctag cgtgagataa
    20821 tcatcagaac tatttgcttt tccctcaata ctatgcccat tatttttaat agaaaatgat
    20881 attggttgat agtttatttg caaaagatta ttatcaactg ttgattttat ttgttctgtt
    20941 ttgatatcta tcggagattg ttcttgccca tttaaacaca tattgtattc tggtttcaat
    21001 tctccccagt gctctggacc agtagtccct ttatatgacc actgcgtatt ttccttcgta
    21061 gattgttttt gcggagcctc ttgttttgct gtgttacatc ccatcaatac tacactcatt
    21121 gttaatataa ggggagtttt ataaacaaac tttaagcctt tcatactgtt tcctccttag
    21181 ttgataaaac attgtattta aagaatattg cttgtaacta agggttctgt tacaaattcg
    21241 ccaaaaatat taagaattta gagaagcatt cctcgattgt tatgcaattt aagttattaa
    21301 atagaaaaat ggaatacgga aactatacag ttaatttacg cgaaaaggaa taactatgct
    21361 tcttacccaa gttagaaaat ctttatacaa agtcaggttg caggcgataa tttttaaata
    21421 ctatgagaaa tggaagtaag agcatattac atttctatcg ttctatttgt cttcatgtag
    21481 tactaaatag aataacttct tacccatacc caaaatcgat tatgtaatct aattatgatt
    21541 caaattactt aacctggtca tatttagttg gcattcctgt attcattccg aagcatggat
    21601 gttttatcat tcttatattc atcatcctca ttcctaattg atattgactt tcattttata
    21661 tttattataa ttatatataa attattaaaa aaaaatcaat atagatttat attctttgat
    21721 gtgatactat gtatttctgg ttatgttgaa gagttttcaa caataagtta ttttcctaaa
    21781 tctacgaaat agagaaatca gtttaattgg atctaccttc catcaacatc aagctaaaaa
    21841 acaacccaaa tataaaaaga ttgaattctc aagatgaaaa tgtacaattt tgttttaagt
    21901 gcgtcataaa atttttaagt tgatggagag atagggtgac ctctactagt tagtggtaat
    21961 attagtttgt gaaaaaaatg tcgaatttgt aagaattttg tgattttttg tcttgtgata
    22021 ctttatattt agtgctaaac tcataataca aagaaagagt agccgaaaat atctccatcc
    22081 gaacagaaaa gactgaagat tcagtctaat tattaaatga ataatactca tgtttactac
    22141 tctttctttg ttttatttta tatatgatat tgaacattat gaatagatag cggggtgaat
    22201 ggaatgtaat tattcggtaa aagtagagga taagtattct gttgtttgta tgacatctta
    22261 atgaataaca tacttattac aaatatttgt agagagaatt gagacgtttt tttcaatcta
    22321 gcaatgaaaa atgtgagttc atacaagtaa ataaacagct acaaataatt atgaatctag
    22381 tcaacaaact gagaatttca ttgaagattc ggtataacga gatttagcca tggagtttat
    22441 cattcatgca gattttaatt aagattctaa atgcataagt agaccgaaat tgataaacgt
    22501 ttttgatgat ctttttgaaa attataagac tatctaatta aaaatctgag aaatgatttt
    22561 taagtgacat ttgaataaac aaaattattt gtgatttata tttttactaa atgaatcaag
    22621 aattaggtag tggtgtagaa caataattta aggacaatat tttggtgtat ataggaggga
    22681 gtataaaata aggatcttat ctcaagagg
//
