LOCUS       NZ_CP035999            23908 bp    DNA     circular CON 10-DEC-2024
DEFINITION  Bacillus mycoides strain BPN37/1 chromosome, complete genome.
ACCESSION   NZ_CP035999
VERSION     NZ_CP035999.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus cereus group.
REFERENCE   1  (bases 1 to 5322329)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5322329)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 108.48400000000001x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739505.1-RS_2024_12_10
            Annotation Date                   :: 12/10/2024 03:54:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,286
            CDSs (total)                      :: 6,132
            Genes (coding)                    :: 5,884
            CDSs (with protein)               :: 5,884
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 248
            CDSs (without protein)            :: 248
            Pseudo Genes (ambiguous residues) :: 0 of 248
            Pseudo Genes (frameshifted)       :: 114 of 248
            Pseudo Genes (incomplete)         :: 146 of 248
            Pseudo Genes (internal stop)      :: 66 of 248
            Pseudo Genes (multiple problems)  :: 68 of 248
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:59:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4687396
            Orig. end                         :: 4711304
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035999.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23908
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="9"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23908
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23908
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13908](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13908
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            222..1490
                     /locus_tag="EXW27_RS24190"
                     /old_locus_tag="EXW27_24575"
     CDS             222..1490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084457.1"
                     /locus_tag="EXW27_RS24190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24575"
                     /product="hypothetical protein"
                     /protein_id="WP_016120649.1"
                     /transl_table=11
                     /translation="MNSIILDKIVVRNNRVDYSFSIKGDLQKYFKTSNHMFLEYNYDVS
                     DIPLSILAIPFVANVVPLVWITNSTIVINELDKSFYICLNNIKNAYQNMFPGVKFKGSV
                     DVGEIIDNVYIPEFEAASLFSGGLDALTTFIRIKDKKPLLVTEYGWHENEIEGSKVWEA
                     DKENAINFVKDNGLENIFIQSNYGTFIIAGNIDHDFREKLNDTWWHGLHHGLAIISAAI
                     PIAFKLKIKCIYIASSNSPLYQVTCASDPTVDNEIKYASGTVFHDGYELTRQEKIKVVV
                     DHYSASKEPVNIRVCFKNEENCCKCEKCLRTIMGIIAEGRDPREYGFNIPSNLYQYVKT
                     SLNSEVKFFTNTFIEMYWNLIQVRMKQNCDCITDKNLLNWFLDYDFKAQRRKALLKYRI
                     TKFFPILKRKISAKFSRVGTQNN"
     gene            1509..3068
                     /locus_tag="EXW27_RS24195"
                     /old_locus_tag="EXW27_24580"
     CDS             1509..3068
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222557.1"
                     /locus_tag="EXW27_RS24195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24580"
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="WP_016120648.1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.1e-07, bitscore:
                     30.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQNSLKNILFGLSGQIISIGMGFVVRTVFIYTLGIEYLGVDGL
                     FTSILLMFSLANLGFDTAIIYSLYRPLAEKDIYKIQALMNLYQKAYRLIGVVVLLLGLS
                     LLPFLDYLVNADTMIKDINIIYLLFLISSVSSYYFVYKQSIIIADQSNYIISKIHTLFI
                     IISNALQIVLLIIISDYIVVLIVQLTLKVIENVYIANKANKLYPFLKEKNNAKLSKADR
                     REFFENLYSLLLYKISGVVINATDNIIISKFIGIIWVGVYSNYLLILNTLNTLLGYLFY
                     SITASVGNLNVKENAEKKYFIFRVINFFNFWIYGFCTVCLWNLINPFITLWLGEEYVFN
                     KYVLFFILLNFFTSGMQNTTTIFRETTGLFKKGKYRPIIAAIINIVVSIILAKQIGIAG
                     VLLGTVISRLCTYFWYDPYIIFKMIFKKSVKVYFIRYILFVVLVLFSVIATDFIGYIFH
                     INIFMDMVIRSILCLIIPNLIFWMVFKEAEEYRYFLNLTRILIKKIKSKILTRKVSNDN
                     YP"
     gene            3403..5637
                     /locus_tag="EXW27_RS24200"
                     /old_locus_tag="EXW27_24585"
     CDS             3403..5637
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269321.1"
                     /locus_tag="EXW27_RS24200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24585"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_147739916.1"
                     /transl_table=11
                     /translation="MWRRRDNLGNLNDLDLVSKPPFHNDILTYDSTQLKWIPKSFEATN
                     STSIYVLELDRWDVKNDGTDAINTSKGINNALVWAAQQGYTEVVLPRGIYLIDKQTPIE
                     PPSHLTLNLNGSTLKMETNNLTGYAIISFRRNQVYSRITNGIIQGDRYTHDYSSGGTHE
                     AGYGIELGSFTPPADGGNNTRFVSLDNLDILDCTGDAITLNSTFGQISPFPTALASSFE
                     QGAINTTDGSLVSSTTKIRSNLQIDMTQMAIVKYGYFGLYGNGFGALGSEIKCDYYDVI
                     FYTSNNIFLSSKTNVQFFDEVEVPNGVSYAKIVLHQGNVPAPANCLINVRVPSFSQYTY
                     IEKCNLHDCRRQGISVCGAKNVYIRDNDIHHIAGTNPQSGLDIEDGYDLNQYIYIERNN
                     FHDNKNYNIIVVNGKFIYISNNSIMNTISNAYVGLSINGGADRVIVTGNNIRLTKVSLL
                     GDVIFSNNYVYGAQVNVQGVYVNRPINILDNIFSNSKMIIDTPFPYAVKVDSCRFINDA
                     DKLNSLSSLYQWTLEMKNEPQTISNCIFEGQDVLYLNYVPVGTVKSGWIFENIIFNNVK
                     NPTLVAGTYTNCFFKDVTFLGITSTGSTLELKDCKFFSIDRNNTLFTVNNLKAFKMMDC
                     HIEKPNGTVLNIQNVSDEIVLGGNTIKITNDTLQRAIIVLDAAFTGKQVIIQNNIINST
                     NLMQVGIDNRTTSITPLVVIQNNVLNNAKITITGREFLQGNIVNGVIDPN"
     gene            6253..6858
                     /locus_tag="EXW27_RS24205"
                     /old_locus_tag="EXW27_24590"
     CDS             6253..6858
                     /EC_number="2.7.8.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002070010.1"
                     /locus_tag="EXW27_RS24205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24590"
                     /product="sugar transferase"
                     /protein_id="WP_002128595.1"
                     /sec_met_domain="Bac_transf (E-value: 2.4e-69, bitscore:
                     230.7, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLFDIFISLLLLICFFFVILLVAIIVKTQIGSPILFRQQRPGL
                     HGKPFYLYKFRTMTNERDRNGELLQDHARLTKVGKFLRKYSLDELPQLINVLKGQLSLV
                     GPRPLLIEYMPLYSKEQAKRHNVRPGITGWAQVNGRNSISWDEKFKLDVWYVENQSFLL
                     DLKILYLTFSKVLKSEGITNNKHVTMPVFKGGIEHGGE"
     gene            6845..7822
                     /locus_tag="EXW27_RS24210"
                     /old_locus_tag="EXW27_24595"
     CDS             6845..7822
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002165241.1"
                     /locus_tag="EXW27_RS24210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24595"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_033729827.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5e-23, bitscore:
                     80.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGNKMNILFTSSGRRVTLIKKFKEVLKQEGIKGKIFTADLKETA
                     PTIYFSDKHFIVPRVNEEGYINELLKICKSEMINLIIPLIDTELTLMANNSKVFEGIGV
                     KVLVSSMELNKIANNKKYTYNFFASNNIPTPRVYSDEEIGRKEYQFPLLIKPYDGSSSK
                     GVTKIMNEKELEFFKDYIPNAMIQEYVSGEEYTIDVMVDFCGNIKTIVPRLRIETRAGE
                     VSKGITKKDFDIIQAAETVIKALPNPIGCITLQCFKKEDGQITFIEINPRFGGGIPLSI
                     EAGANFPLWTIKMCQGEVFIDKDFNWRENLTMLRYDEAVFMESI"
     gene            7824..8519
                     /locus_tag="EXW27_RS24215"
                     /old_locus_tag="EXW27_24600"
     CDS             7824..8519
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016086741.1"
                     /locus_tag="EXW27_RS24215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24600"
                     /product="HAD family hydrolase"
                     /protein_id="WP_002128593.1"
                     /sec_met_domain="HAD_2 (E-value: 6.7e-24, bitscore: 83.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIKAIVFDMDDTLYKEKDYVVSGFKAVDDWIKEKYKKTGFYNIA
                     IQLFDSGERRFVFNETLEKLNIPYDEKLISNLIEQYRFHKPDIQLLDEADWVLNNLVNT
                     VKIGLISDGYLVAQEKKINALKLKERFHSIILTDELGKEYWKPSQIPYEKISKELQVPH
                     QQCVYIGDNLSKDFITAKKLKWLTIHINREGGIHHNLIVEQAYKAHYTIDNLRRLSDIS
                     VLEHMFLDT"
     gene            8550..9713
                     /locus_tag="EXW27_RS24220"
                     /old_locus_tag="EXW27_24605"
     CDS             8550..9713
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (42-168). E-value:
                     1.2e-08. Score: 26.5. Matches aSDomain:
                     nrpspksdomains_EXW27_RS24220_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557690.1"
                     /locus_tag="EXW27_RS24220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24605"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_050000629.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.7e-97,
                     bitscore: 323.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-06, bitscore:
                     26.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTVQHKKRIYLSSPHMSRNEQKYIQNAFDTNWIAPLGPNVDGFE
                     RELASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSFTFVASANPIVYLGAEPV
                     FIDSEPETWNMSPNALAHALYEANKVGKLPKAIILVHLYGQSAKLDEILSLCNQYNVPI
                     VEDAAESLGSTYKGKASGTFGRFGVYSFNGNKIITTSGGGMLVSNDVEALERARFLATQ
                     AKDPAPHYEHSEIGYNYRMSNILAGVGRGQLEVLEDRVRTRRCIYKRYYEALSHMPGFY
                     FMPELENTRSNRWLTTLTIDEKESGISIGKLLRTLAEENIEARPMWKPLHMQSLFKEKK
                     YYPHSKNEDVSQYLFQSGICLPSGSNMLAEDQQRVIQGILKAVEWKN"
     aSDomain        8676..9053
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS24220_Aminotran_1_2.1"
                     /evalue="1.20E-08"
                     /label="EXW27_RS24220_Aminotran_1_2.1"
                     /locus_tag="EXW27_RS24220"
                     /protein_end="168"
                     /protein_start="42"
                     /score="26.5"
                     /tool="antismash"
                     /translation="GFERELASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSF
                     TFVASANPIVYLGAEPVFIDSEPETWNMSPNALAHALYEANKVGKLPKAIILVHLYGQS
                     AKLDEILSLCNQYNVPIVEDAA"
     gene            10001..11938
                     /locus_tag="EXW27_RS24225"
                     /old_locus_tag="EXW27_24610"
     CDS             10001..11938
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274520.1"
                     /locus_tag="EXW27_RS24225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24610"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_147739915.1"
                     /sec_met_domain="GATase_7 (E-value: 5.6e-20, bitscore:
                     69.8, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.6e-22, bitscore:
                     79.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIIHFTNEPVSIENGREVMSRLYKYPADDIQIWHKENAFL
                     GCHAQWITPESVGEQLPFYNYEKQLAITADAIIDNRDELFEKLQVDYSDRKNMTDSELI
                     LLSYQKWGEAAPKYLVGDFAFMIWDEKKQTLFGARDFSGSRTLYFYRGEEKFTFCTIIN
                     PLFSLPYVEKKLNKQWIAEFLAIPVNFESVDPQLTVYKYIEQVPPSHTILVKEGEVKFS
                     RYYTPTVGEMLNLKSNEEYEEAFREVYQSAVKARLRTHHQVGAHLSGGLDSGSVVSFAA
                     SDLRAENKKLHTYSYVPVEGFEDWTHKGRIADERPFIQSTVEHVGNIQDYYLELPERSP
                     LSEIDDWLETMEMPYKFFENTFWLSGVYEKASQNGIGVLLSGQRGNWTVSWGPILDYQA
                     MLLKKLHWIRFYRELHLYSRNIGVKKSRVFEVVRRKAFPFLHQLLFSGKQDANSAIINP
                     EFAREMNVFDRLREQDIDITGTSISNAYDMKREQFEKPYYWSINGTYETKLSLRYALWD
                     RDPTNDLRLIQFCLSVPEEQYVQNGLDRALIRRATKNFLPDKVRLNQRVRGIQGADGVY
                     RMAPFWNEFIEEVEELSVDPVISEFLNVEVIKKAISKICKEPRPEYAFDVDFRILMRSL
                     IFYRFIKKAM"
     gene            11954..12079
                     /locus_tag="EXW27_RS24230"
                     /old_locus_tag="EXW27_24615"
     CDS             11954..12079
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172970.1"
                     /locus_tag="EXW27_RS24230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24615"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_000712621.1"
                     /transl_table=11
                     /translation="MKKEWKQPVLEVLNINMTMAGPGHKYPDAVQPDPDDPVKYS"
     CDS_motif       11954..12013
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKEWKQPVLEVLNINMTMA"
                     /locus_tag="EXW27_RS24230_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12014..12079
                     /prepeptide="core"
                     /locus_tag="EXW27_RS24230_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-15.80"
                     /molecular_weight="2264.4"
                     /monoisotopic_mass="2263.0"
                     /core_sequence="GPGHKYPDAVQPDPDDPVKYS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEWKQPVLEVLNINMTMA"
                     /leader_location="[11953:12013](+)"
     gene            12156..13127
                     /locus_tag="EXW27_RS24235"
                     /old_locus_tag="EXW27_24620"
     CDS             12156..13127
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108921.1"
                     /locus_tag="EXW27_RS24235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24620"
                     /product="aldolase"
                     /protein_id="WP_002128587.1"
                     /transl_table=11
                     /translation="MFDSMGNVLYQAFGLKIVSEIPLPELSQLNEKKEMADVQVEITDL
                     SEQWGEYSAEKQKTIVVEDDIVMFHVPQTAIFAIQSGEKITFSPMANAEEDKIRLYILG
                     TCMGALLMQRKILPLHGSVIAIDGKAYALIGDSGAGKSTLASAFLNKGYKLLSDDVVAV
                     SLLNKNTAIVHPSYAQQKLWQESINELGMEVAQFSPLFERETKYAVPVNSQFFPDPLPL
                     AGVIELVKTQGEDIEMTRIEGLARLYKLYRHTFRNSLISKLGLMEWHFETSSNIASGME
                     IFQVSRPASRFTAHELVEVILNTIQKGSMVDGCPLEKNIIRT"
     gene            13090..13398
                     /locus_tag="EXW27_RS24240"
                     /old_locus_tag="EXW27_24625"
     CDS             13090..13398
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128586.1"
                     /locus_tag="EXW27_RS24240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24625"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_002128586.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.9e-26,
                     bitscore: 88.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-15, bitscore: 54.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVHSRKISLEHNVVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEI
                     GGEIWELIEKPIIINQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQIKDQPNR"
     aSDomain        13129..13377
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW27_RS24240_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.00E-28"
                     /identifier="RREFam002.1"
                     /label="EXW27_RS24240"
                     /locus_tag="EXW27_RS24240"
                     /protein_end="96"
                     /protein_start="13"
                     /score="88.7"
                     /tool="antismash"
                     /translation="VVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEIGGEIWELIEKPII
                     INQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQI"
     gene            13435..13908
                     /locus_tag="EXW27_RS24245"
                     /old_locus_tag="EXW27_24630"
     CDS             13435..13908
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012261438.1"
                     /locus_tag="EXW27_RS24245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24630"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_033713202.1"
                     /sec_met_domain="PF13471 (E-value: 4.7e-23, bitscore: 79.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVKRLRMFLSLNMKTKLLFLEAFIFLGWARVLKNITFSKVAPS
                     LGDYMSETSSTHIQPHGDTLKKVSEAISIMSRYTFWESQCLVKAIAGMKMLEKRHIEST
                     LYLGTAKDSHGELIAHAWLRSGSFYVTGSEGMEKFTVVGSFAKRLSEDTIKGE"
     gene            13910..15097
                     /locus_tag="EXW27_RS24250"
                     /old_locus_tag="EXW27_24635"
     CDS             13910..15097
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409755.1"
                     /locus_tag="EXW27_RS24250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24635"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_002128583.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 4.4e-66, bitscore:
                     221.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKDFGLNVEFMSKELKLLFAILKLQDDETMQTYSNEWFSDIDWE
                     VFLEQAVHHRVYPVIYQKLKQVDKELIPSHIVQTLTRKYKRNTFQMLYLSAEMERINKL
                     CNENEIRTIFLKGPVLSQDLYGDLSLRTSCDLDVLIPIQNLEKAEKLLLEQGYVKDDYI
                     QTILSDWKWRHHHITFFHPTRRIKLEIHWRLNPGPGKEPGFEELWKRKRKSTLTSNSVY
                     MLGKEDLFLFLVSHGARHGWSRLRWLVDIKKIVDQDLNWSEIHKLMRKYQMLHLGGQAL
                     ILASQLLGVRLDERMMELVTKKHSKQLAQEALFYFKQMINLHTDPVPEEVLAYHSRHLF
                     SLMSNQQKILYIMSQLYPYPIDAKTLPLPKFLHFLYFPLRPFLCLWRKTKKLALL"
     gene            15109..16908
                     /locus_tag="EXW27_RS24255"
                     /old_locus_tag="EXW27_24640"
     CDS             15109..16908
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096316.1"
                     /locus_tag="EXW27_RS24255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24640"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_078178531.1"
                     /transl_table=11
                     /translation="MNHIIYFIKKLYSSAGKILYVNLFGMVLISLLEGIGIILLIPMIS
                     MTGIINIGEETAFIAPVYRFLQDFPKTTSLISILGIYILIVLGQNLLQRNITLRDARTQ
                     QAFVRELRIETYSMILKAKWSFFLEKRKTNLINILTTELARVSYGVNLILQLLAVILFT
                     FIQVGLAFLLSPQITIFVLVFGLLFLVASRAFIKKARILGVKTSKLAQDYLSGITDHFN
                     GIKDIKSNTLEASRLDWLQSITEKMSNEQMEYMRIRSNSQLFYKVSMAILIAFFILLSV
                     SIFKAQPTQLLLIILIFSRLWPRFMTIQSNLEQLAASIPAFKSLWELQGECNEAIEMQD
                     IHQQKHIKPICIEQGIECKGIYFRYNKKEHLYALQNINVKIPINSMTAIVGHSGAGKST
                     LIDVLMGLIQPEKGQVLIDGTPLTSENLLSLRRAISYVPQDPFLFNASIRENLLMIEPN
                     ASEEQIWTALDFAAAAEFVRMLPKGLDTLIGDRGVRLSGGERQRLVLARAILRQPSILV
                     LDEATSALDTENEVKIQSAIERLKGTMTIVVIAHRLSTIRNADQVIVLGKGEIVQKGEF
                     NQLAKERKGVFRNLLGSQMEVGS"
     gene            17136..17459
                     /locus_tag="EXW27_RS24260"
                     /old_locus_tag="EXW27_24645"
     CDS             17136..17459
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016105867.1"
                     /locus_tag="EXW27_RS24260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24645"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_002066545.1"
                     /transl_table=11
                     /translation="MNVQFKKGVLELCVLALVKRKDCYGYELVQQISNKFLISEGSVYP
                     LLRRLTKEGYFQTYLKESTEGPPRKYYQLTEQGEMQLTLLVTEWRDFAKGVQEIIEGVE
                     WDE"
     gene            17452..17994
                     /locus_tag="EXW27_RS24265"
                     /old_locus_tag="EXW27_24650"
     CDS             17452..17994
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031379.1"
                     /locus_tag="EXW27_RS24265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24650"
                     /product="DUF1700 domain-containing protein"
                     /protein_id="WP_002128581.1"
                     /transl_table=11
                     /translation="MSKEQFLKELSSHLRKLPEEERQDILFDYEEHFQFGMEEGKTESE
                     IIKGLGSPKVIAKDLLAMYRFDEMKKDPSTSNVTRAVMAAVGLSLFNFIIVLGPLVAII
                     AFIFSFWVGGIASVVTPFFVIVKVFMGTFIWLDLFVSITFVGVGLLLCIVAYYSTKWFK
                     RLCVRYVVWNFKMIKGE"
     gene            17995..18798
                     /locus_tag="EXW27_RS24270"
                     /old_locus_tag="EXW27_24655"
     CDS             17995..18798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016512438.1"
                     /locus_tag="EXW27_RS24270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24655"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_002014437.1"
                     /transl_table=11
                     /translation="MMKKILLVAIACIIIGVIGISQTYEKAVQTAEKGDKEDVIKNETL
                     KNVEVKLDAGDIVVQKSPDSSFYVKQKGDVSKQEIRIAEDGDTLKIIGEIEKGVSFDFS
                     FYNFGFQTPTLTILVPERSYQEIKVNSSAGQIEISNVKSDRVSVETLAGEVDLKHVTAK
                     SVEGSTKAGEVNFKKVIGKVTAKTASGDIDIIDHDSKYDLEVSSTAGDVDITLLEKPQD
                     AVITGQTAAGDVTIFNEDNKNITIGNGSKKISGKTAAGDVTIETR"
     gene            complement(18902..19516)
                     /gene="lexA"
                     /locus_tag="EXW27_RS24275"
                     /old_locus_tag="EXW27_24660"
     CDS             complement(18902..19516)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413738.1"
                     /locus_tag="EXW27_RS24275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24660"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_002087894.1"
                     /transl_table=11
                     /translation="MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHG
                     HLSRLEEKGYIRRDPTKPRAIEILGDNRTETQSVIQVPIIGKVTAGLPITAVESVEDHF
                     PLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATV
                     KRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH"
     misc_feature    19584..19597
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.42"
                     /tool="antismash"
     gene            19658..20314
                     /locus_tag="EXW27_RS24280"
                     /old_locus_tag="EXW27_24665"
     CDS             19658..20314
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016111193.1"
                     /locus_tag="EXW27_RS24280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24665"
                     /product="recombinase family protein"
                     /protein_id="WP_002128580.1"
                     /transl_table=11
                     /translation="MNAIIYARVSTTKEEQETSLLRQKDELLHLAERYQMDVTKVIEEQ
                     ASGYTIERDGILEVLDTIRDEQVDVLLIQDETRLGRGNAKIALMHCLHKEGIKVYTHTH
                     SGELQLSDSDSMVLNIIGIVEEYQRKIHNLKIKRGMQRAVEKGFRPENNLKNRHLSVGR
                     EKKEVPIEEIVRLRRNELTFEEIAATLRGFGHDVSKATVHRRYVEYTKQLLDKED"
     gene            20360..20599
                     /locus_tag="EXW27_RS24285"
                     /old_locus_tag="EXW27_24670"
     CDS             20360..20599
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172959.1"
                     /locus_tag="EXW27_RS24285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24670"
                     /product="DUF896 domain-containing protein"
                     /protein_id="WP_002014431.1"
                     /transl_table=11
                     /translation="MPSQELIERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNM
                     LNELKGIKVVNEEGTDVTPAKLKALKKQDNAKLN"
     gene            complement(20640..22223)
                     /locus_tag="EXW27_RS24290"
                     /old_locus_tag="EXW27_24675"
     CDS             complement(20640..22223)
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199635.1"
                     /locus_tag="EXW27_RS24290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24675"
                     /product="bifunctional UDP-sugar hydrolase/5'-nucleotidase"
                     /protein_id="WP_002128579.1"
                     /transl_table=11
                     /translation="MNQNQIVTLNILLTSDVHGTVYPIHYQDNSKAEIGLAKISTLIKK
                     ERSQNANVLLIDNGDFIQGTPFTYHYATYEKDMENPMSLLANYLEYDIAIIGNHEFNYG
                     MDILNNAVTTANSPYLSANILDKNRKEPYFGKPYIIKHIESNIKIAILGVTTHYIPHWE
                     QAHHIKDLQFEDAFETTKKWVSYIRKHEKPDLLVVAYHGGFERDLQTGVPTEVLTGENQ
                     GYAMCHEIEGIDILLTGHQHREIAHTVINGVTILQTGCNGHSVGKVTVTFEKAEQKWVK
                     KESYSELLPVQGIAADQDVLSLVANYEEKTQNWLDKPIGIIYGDMQISDAMQTRLQDHP
                     FIEFINKIQMDIANVSISCTSLFHNTSPGFPKHVTMRDIVSNYIYPNTLKVIRITGADI
                     KNALELSASYFTLKADGTIIVNPTYIEPKPQHYNYDMWEGISYVLNISKPIGERVESLQ
                     YKGAPLNMNEEYDVVMNNYRASGGGNFFMFQNKPVVKDIPTDMSELIANYILKHKRIEA
                     TKNENWKVIK"
     misc_feature    complement(22372..22388)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 28.44"
                     /tool="antismash"
     gene            22409..23347
                     /locus_tag="EXW27_RS24295"
                     /old_locus_tag="EXW27_24680"
     CDS             22409..23347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913375.1"
                     /locus_tag="EXW27_RS24295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_24680"
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_002137777.1"
                     /transl_table=11
                     /translation="MLKKVFAMSTTVVLAAGLLSGCGTKESSASKNEDTKKGYVPKTLN
                     VQFVPSQNADTLEAKAKPLEKLLSDKLNIPVKVSISTNYNTIVEAMASKQVDVGFLPPT
                     AYVLAHEKKAANVILQAQRFGVDDETGAPTKDLVDVYKSEFVVKKDSNINSVKDLKGKK
                     IGYQDVTSSAGYVWPAAVLLKEGIDPLKDVKPVTLKGHDQSLIALLNGDVDAAVVFQDA
                     RNIVKKDYPNIFDQTKIVKFTEKIPNDTISVRSDLDAEWSKKLQDAFIEIGKNEEGHKI
                     IKEVYSHEGYVKSDDSKFDIVREYGKKVKTQ"
ORIGIN
        1 tgcaataatt atctccatag atgaaagagc taaggggatg ggcgaaacgt ataatttaaa
       61 tctgattgat agagaagatt taaataatct tgaaaaaatg ataaattcag agtttatcac
      121 ggatgttcaa gtgaattttg atgtagtaaa tcaatggtta aaacagttct ctaattaata
      181 aatgtacttt gataaaaatg gcgatttatt aggaggctca aatgaatagt ataattctcg
      241 ataaaattgt cgtaagaaat aatagagttg attattcttt tagtattaag ggggatttac
      301 aaaagtattt taagacaagt aatcatatgt ttcttgaata taactatgat gtatctgata
      361 tccctttaag tattttggct attccgtttg ttgcaaatgt agttcctctt gtatggatta
      421 ctaattcaac aatagtaata aatgaactag ataaatcttt ttatatttgt ttaaataata
      481 taaaaaatgc atatcaaaac atgtttcctg gtgtgaaatt taaaggatcc gtggatgtag
      541 gagaaattat tgataatgtt tacattccgg aatttgaagc ggcatcttta tttagtgggg
      601 gattagatgc acttactaca tttataagaa taaaagataa aaaacccttg ctagttactg
      661 aatatggatg gcatgaaaat gaaatagagg gtagtaaagt atgggaggca gataaagaaa
      721 atgccataaa ttttgtaaag gataatggac tagaaaatat ttttatacaa tccaactatg
      781 ggacctttat aattgcaggg aacattgacc atgattttag agaaaagtta aacgatacat
      841 ggtggcatgg attgcatcat ggtctagcta taatatctgc agctattcca atagctttta
      901 aacttaagat aaaatgtata tacattgcaa gctctaattc tccattatat caagttactt
      961 gtgcatctga tccaactgtg gataatgaaa taaaatatgc atctggaaca gtatttcatg
     1021 atggatacga acttactagg caagaaaaga ttaaagttgt tgtggaccat tattcagcta
     1081 gtaaagaacc tgttaatatc agggtatgtt ttaaaaatga agaaaattgt tgtaaatgtg
     1141 aaaaatgttt aagaacaatt atgggaatta ttgctgaagg gagagatcct cgtgaatatg
     1201 gttttaatat tccaagtaat ctttatcagt acgttaaaac ttctttaaat agtgaggtga
     1261 agttttttac taatacattc attgaaatgt attggaattt aatccaagtg cgaatgaaac
     1321 aaaattgtga ttgtattaca gataaaaatt tactaaattg gtttctagat tatgatttca
     1381 aggcgcaacg aagaaaagcg ttattaaaat acaggataac aaagtttttc cctattttaa
     1441 aaaggaagat tagtgccaaa tttagtagag tgggtacgca aaacaactaa aatatagaag
     1501 gtattacgat gagaatacaa aattccttaa aaaatatttt attcggtttg tctggacaaa
     1561 taattagtat tggcatggga tttgttgttc gaactgtttt tatttataca ctcggtatag
     1621 aatatttagg tgtggatggg ctttttacaa gtatactatt gatgttttcc ctagctaatt
     1681 taggctttga tacagctata atttatagtt tatataggcc attagctgag aaggatatct
     1741 ataaaataca ggcattaatg aatttatatc aaaaagcata cagattaata ggagtagtag
     1801 ttttattatt agggttatct ctattaccat ttcttgatta tttagtgaat gcagatacta
     1861 tgattaaaga cattaacatt atctatcttt tatttttaat aagttcggtg tcatcatatt
     1921 attttgtata taagcaatct attattattg ctgatcaaag taactatatc atttctaaaa
     1981 tacacacttt gttcataatt atatctaacg cattacaaat tgttttatta ataattatta
     2041 gtgattacat tgtagtactg atagttcaat taacattgaa agtaattgag aatgtatata
     2101 ttgcaaataa ggcaaataaa ttatatccat ttttaaaaga aaaaaataat gcgaaattat
     2161 ctaaggcaga cagacgagag ttttttgaga atttgtattc cttgttacta tataaaatta
     2221 gtggtgtagt aattaatgca acagataata taattatatc gaaattcatt ggaattattt
     2281 gggttggtgt gtattcaaat tatttgttga tcttaaatac attaaatacc ttattaggct
     2341 atttgtttta ttctatcact gctagtgttg gaaatttgaa tgtgaaagaa aatgcagaaa
     2401 aaaaatattt tatttttcgt gtaattaact tttttaattt ttggatatat ggattttgta
     2461 cagtttgcct ttggaatttg ataaatccat ttataacact ctggttaggt gaggaatatg
     2521 tgtttaataa gtatgtatta tttttcatat tacttaattt tttcacttca ggaatgcaaa
     2581 atacaactac aatttttaga gaaaccacag gtttatttaa aaaagggaag tatagaccta
     2641 tcatagcggc aattataaat attgtagttt ctataattct cgcgaaacaa ataggaatag
     2701 caggagtgct tttagggact gttattagta gattatgtac ttacttttgg tatgatcctt
     2761 atattatatt taaaatgatt tttaaaaaat ctgtaaaagt atattttatt agatatattt
     2821 tgtttgtagt gcttgtatta ttttctgtta tagcaacgga ttttattggt tatatttttc
     2881 acataaatat atttatggac atggtaatac gtagtatttt gtgcctgatt attccgaatt
     2941 tgatcttttg gatggtattt aaagaggcgg aagagtatag atatttcctt aatttaaccc
     3001 gaatattaat aaaaaaaata aagtcgaaaa tattaactcg gaaagtttcg aatgataatt
     3061 atccataaat tattatttta ttttttccat atcacagtaa agaatgcttt atttacggaa
     3121 gagattttag gttgttctga aaataatagt aggggagtta tgtataaaga gcatagtgtc
     3181 tttttaataa aattgtaagt ttaaatagta taaataaaag ggtattgaaa taaaaacagc
     3241 tagtaagaat agatctattt aggaaggaga aaggaattgt gaaaagactt tctaaataat
     3301 ggatctctaa aaacaataaa aagtgatgtt acttctctta tatccaatca atttacctta
     3361 tgaaacataa gatgtagaaa agcaaaaaag aggtgtgaat tgatgtggag aagaagggat
     3421 aatcttggga atttgaatga tttagatttg gtgtccaagc ctccttttca taatgacatt
     3481 ttaacttatg atagtacgca attaaaatgg attccaaaat catttgaagc tacaaattct
     3541 acaagtatat atgtattaga attagataga tgggatgtta agaatgatgg gactgatgct
     3601 atcaatactt ccaaaggtat taataatgct ttagtttggg cggctcaaca aggttatacg
     3661 gaagttgtgt tacctagagg aatatatttg attgataaac aaacacccat cgaaccacca
     3721 agtcatttaa ctttgaatct aaacggttca acattaaaaa tggaaacaaa taatttgact
     3781 ggatatgcaa ttataagttt tcgtagaaat caagtatatt ctaggataac aaatggtatt
     3841 atccaaggag atagatatac acatgattat tctagtgggg gaacacatga ggcagggtac
     3901 ggcattgaat tggggagttt tactccacct gctgatgggg ggaacaatac acggtttgta
     3961 tctttagata atctagatat tttagattgt acaggagatg ccattacact gaacagtact
     4021 tttgggcaga tttcaccttt tcctacagca ttagcaagtt catttgaaca gggagcaatt
     4081 aatacaacag atggttcatt agtaagtagt acaacaaaga tacgttccaa tttgcaaatt
     4141 gatatgaccc aaatggctat tgtaaagtat ggttactttg gattatatgg aaatggattt
     4201 ggagcattgg gttctgaaat aaaatgcgat tattatgatg tcatttttta cacttcaaat
     4261 aatatatttt tatcttcaaa aaccaatgta caattctttg atgaagtaga agtccctaat
     4321 ggagtaagtt atgctaaaat tgttttgcat caagggaatg ttcctgctcc tgcaaattgt
     4381 ttaataaatg ttcgggtgcc ttctttttca caatatactt atatagaaaa atgtaattta
     4441 catgattgcc gtagacaagg gattagtgta tgtggggcaa agaatgtata tattcgagat
     4501 aatgatattc atcacatcgc aggtaccaat ccacaaagtg gactagatat tgaagatgga
     4561 tatgatttaa atcaatatat atacattgaa agaaataatt ttcatgataa taaaaattat
     4621 aatattattg ttgtaaatgg gaaatttatc tatatatcga ataattctat tatgaatacc
     4681 atttcaaatg cttatgttgg gctatctatt aatggtggtg cagatagggt aatcgtaaca
     4741 gggaataata tccgattaac caaggtctct ttgttaggag atgttatttt ttccaataat
     4801 tatgtatacg gagcgcaagt aaatgttcaa ggtgtatatg taaatcgacc tattaatata
     4861 ttagataata ttttttctaa tagtaaaatg attattgata ccccctttcc atatgcggtt
     4921 aaagttgatt cctgtcgctt tataaacgat gcagataaac taaattcctt gtcatcattg
     4981 tatcagtgga cattagagat gaaaaatgag ccgcaaacta tctcaaattg tatatttgaa
     5041 ggacaagacg ttttgtattt aaattatgta ccagtaggaa cagttaaatc aggatggata
     5101 tttgaaaata ttatatttaa taatgttaaa aacccaacct tagttgcagg gacatataca
     5161 aattgctttt ttaaggacgt aacctttttg gggataacaa gtacaggaag cactttagaa
     5221 ttaaaagatt gcaagttctt tagtatagat agaaataaca cgttatttac agtgaataac
     5281 ctcaaagcat tcaagatgat ggattgtcat atagaaaaac caaatggtac ggtcttgaat
     5341 attcaaaatg tatctgatga aatagtgtta gggggaaata ctataaaaat tacaaatgat
     5401 actcttcaga gagctattat tgttttggat gcagcgttta ctggtaagca agtgataatt
     5461 caaaataata ttataaattc cacaaatttg atgcaagttg ggatagataa tagaacaacg
     5521 agtattacac ccctagtagt aattcaaaac aacgtgttga ataatgcgaa aattacaatt
     5581 acagggaggg aatttctgca agggaatata gttaatggtg taatagatcc aaattaatgc
     5641 atggtgataa ttaaatttga atagtttcaa aaaattatga gaaatgaagt agagtggctc
     5701 ttaataaata tgtccataaa gtattatata atggtacatg gaaggatttt gtccaatgta
     5761 attattcgaa atagtctaat tcctaataga taataggttt attgactttt agttactact
     5821 atagaataga gaaaagctat tatgttttta taaacataat agctttttat tattacgtta
     5881 actgcatact aaaaaatagt gtgtaggaga atttttaaat aataaatgga ttttttaata
     5941 tactactaag cgttgtttat aaaactgtgt ttgtgaatat attttttgag atttttacag
     6001 tgtgtaatag tctcttggat aagcatttgg aaaaatatat tttgcaccta tgtgtattgc
     6061 tttcttctac ttattaagtt ttaaagctgt gtactataga aaatgtttgc aggtgataag
     6121 taaagagaaa ttgaatacaa ttctttaatt acaacttaag aatacttgat ttcaatccgt
     6181 aatgaatact ttgtagatta tttaactttg gaaaagcatt tgtaataatt taagatgggg
     6241 gaatgattgg taatgaagag actgtttgat atctttattt ctttattatt attaatttgc
     6301 ttttttttcg ttattctttt agtagcaatt atagttaaaa ctcagatagg atcacccatt
     6361 ttatttagac aacaacgtcc agggttacat ggaaaacctt tttatcttta taaatttcgt
     6421 acgatgacca atgagcgaga tcgtaatggg gagctgttac aagatcatgc tagattaact
     6481 aaagttggaa aatttcttag aaaatatagt ttagacgaat taccacaatt aataaatgtg
     6541 ctaaaaggtc aattaagttt ggtgggcccc cgcccattat taatagaata tatgccttta
     6601 tattcgaaag agcaagctaa aaggcataat gtaagacccg gaatcactgg atgggctcaa
     6661 gttaatggaa gaaatagtat ctcatgggat gagaaattta aattagatgt atggtatgtt
     6721 gagaatcaaa gttttctttt agatttgaaa attttatatc taacttttag taaggtttta
     6781 aagtcggaag ggataacaaa taataagcat gtgactatgc cagtttttaa ggggggaatc
     6841 gagcatgggg gggaataaaa tgaatatttt gtttactagc tctggtagga gggtcacctt
     6901 aattaaaaaa tttaaggaag tacttaaaca agaaggaatc aaaggaaaaa tctttactgc
     6961 agacttaaaa gaaactgctc ccaccattta ctttagcgat aagcatttta ttgttccgcg
     7021 tgtaaatgaa gagggatata taaatgaatt attaaaaata tgtaaatctg aaatgataaa
     7081 tctaataatt ccgttaattg atacagaatt aacccttatg gctaataatt cgaaggtttt
     7141 cgaaggtatt ggtgtaaaag tattagtttc tagtatggaa ttaaataaga ttgctaataa
     7201 caaaaaatac acatataact tttttgcatc taataatata ccaacaccta gagtatatag
     7261 tgatgaagag attggaagaa aagaatatca atttccacta ttaattaaac cttatgatgg
     7321 cagttctagt aaaggtgtaa caaaaataat gaatgaaaag gaattggaat tttttaagga
     7381 ttatatacct aacgctatga tacaagagta cgtttcagga gaagaataca ctatagatgt
     7441 catggtagat ttctgtggga atataaaaac aatcgttcct agattgcgta tagagacacg
     7501 agcaggtgag gtaagtaaag gtataaccaa gaaggatttt gatatcatcc aagcagcaga
     7561 aactgtaata aaagctcttc ctaatcctat tgggtgtatt actttacaat gttttaaaaa
     7621 ggaggatgga caaattacgt ttattgaaat aaaccctcgt tttggaggag gaataccact
     7681 atcaatagaa gcaggagcga attttccact ttggacaatt aaaatgtgtc agggggaagt
     7741 ctttatagat aaggacttta attggagaga aaatttaaca atgcttagat atgatgaagc
     7801 ggtttttatg gagagtattt aagatgatga ttaaagcaat tgtttttgat atggatgata
     7861 ctttatataa agagaaagat tatgttgtaa gtggttttaa agcagtggat gattggatta
     7921 aagaaaagta taagaaaacc ggattttata atattgcaat tcaattattc gattcggggg
     7981 aaagaaggtt cgtgtttaat gaaacactag aaaagttaaa cattccttac gatgaaaaat
     8041 tgattagtaa tttgatagaa cagtataggt ttcataaacc agatattcaa ttgttggatg
     8101 aagcggattg ggtactaaat aatttagtta ataccgttaa aataggactt atttcagacg
     8161 gatatttagt tgcccaagaa aagaaaatta atgcattaaa gttaaaagag agatttcatt
     8221 cgataattct cactgatgag ctgggaaaag aatattggaa gccgagccaa attccttatg
     8281 aaaaaataag taaggaacta caggtgcctc atcagcaatg tgtctatata ggagataatt
     8341 taagtaagga ttttataaca gccaagaaat tgaaatggtt aacgatccat attaatagag
     8401 aaggtggaat tcaccataat cttatagttg agcaagctta taaagcacat tatacaattg
     8461 ataatttaag gagattatct gatatatctg tattagagca tatgttttta gatacatagt
     8521 atttaaatat gtataaagga tgtgtttaca tgcacacagt tcagcataaa aagcgaattt
     8581 acctttcctc tccgcacatg agtaggaatg aacaaaaata tattcaaaat gcatttgata
     8641 caaactggat tgcccctctt ggcccaaatg ttgatggatt tgaaagagaa cttgcatctt
     8701 ttgtaggagt gaaaggtggg gctgcagtta gttcaggtac ggctgctatt catttagctt
     8761 tgcgattatt agatgtccaa aagggagata cagtgttttg ttcaagtttt acttttgtag
     8821 cgagtgcgaa tccgattgtt tatttgggag ctgaaccagt atttattgac tcagaaccgg
     8881 aaacatggaa tatgtcaccg aatgcattgg cacatgcatt gtatgaagct aataaagtgg
     8941 ggaaattacc aaaggctatc attcttgttc atttatatgg tcagagtgct aaactagatg
     9001 aaattctttc actttgtaat caatataatg ttcctatagt tgaggatgca gcagaatctc
     9061 ttggatctac atataaagga aaagcaagcg gtacatttgg gaggtttggg gtttattcat
     9121 ttaacggaaa taaaatcatt acaacttcag gtggtggaat gctagtttct aatgatgtag
     9181 aagcattaga aagagcgagg tttttagcga cacaagcaaa ggatccagct ccacattatg
     9241 agcatagtga gataggttac aattatagaa tgagtaatat attagctggt gttgggagag
     9301 ggcaattaga agtgttagaa gatagagtga ggactagaag gtgtatatat aaacggtatt
     9361 atgaagcact atctcacatg ccaggatttt attttatgcc tgaattagaa aatactcgct
     9421 ctaatcgttg gcttactaca ttgacaattg atgaaaagga atccgggatc tctattggga
     9481 aattgttgag aactttagca gaagagaata ttgaagcgcg tcctatgtgg aagccacttc
     9541 atatgcagtc gctctttaaa gagaagaagt attatccgca tagcaaaaat gaagatgtgt
     9601 cgcagtacct atttcaaagt gggatttgtt tgccttcagg atctaatatg ttagctgaag
     9661 atcaacaaag ggtaattcaa ggtattttaa aagctgtaga atggaagaat taaaagtaag
     9721 taaaagtgga attagatttg tatacgtacc accatttgtt ctttataatg aatttttaag
     9781 ggaattgttt ggggacattc agtttcaatt gacataaaaa agggataatt ataggctttt
     9841 aatatctata tcttagtctg aaagtaaatt taagcatgta attgagaaag taataaaaca
     9901 aataatttcg ttcgttaaaa agaatgataa agaggtatgt ttaacgaatt taatatgtaa
     9961 atagtatttg tagtaacttt tcatatatta ggaggaagaa atgagcgcta tagctggcat
    10021 tatccacttt actaatgagc ctgtatcaat tgagaacgga agagaagtaa tgagtcgttt
    10081 atacaaatat cctgccgatg atattcaaat atggcacaaa gaaaatgctt ttctaggatg
    10141 tcatgcacaa tggattacac cagagtcagt tggtgaacaa ttaccctttt ataattatga
    10201 aaagcaactg gcaattacag cagatgctat tattgataat cgtgatgagt tatttgaaaa
    10261 actacaagtg gattattcgg atagaaaaaa catgacagat agcgagttaa ttttactctc
    10321 ttatcagaaa tggggggaag cggctccaaa atatttggta ggcgattttg cctttatgat
    10381 ttgggatgag aaaaaacaaa ctctttttgg tgccagagat ttttcaggaa gtcggacact
    10441 ttatttttat cgtggtgagg aaaaatttac tttttgtact attataaatc cgttattttc
    10501 tctaccatat gttgagaaga aattgaataa gcagtggatt gctgaatttc tagctatacc
    10561 tgtaaatttc gaatcggtag atccacagtt aacagtttac aaatatatag aacaagtgcc
    10621 tccatcacac actattttgg taaaggaagg cgaagtgaag ttttcgcgat actatacacc
    10681 aactgttggg gaaatgctta atttaaaatc aaatgaagag tatgaagagg cgtttcgaga
    10741 ggtgtatcaa agtgcagtga aggcacgttt acgaacacat caccaagtag gagctcattt
    10801 gagcggaggg ctagactcag gttctgtcgt tagttttgct gcaagtgatt tacgggctga
    10861 aaataaaaaa ttacatacgt acagttatgt tccagtagaa ggatttgaag attggacaca
    10921 caaaggtaga atagctgacg aaagaccatt tattcaatcg actgtcgagc atgtagggaa
    10981 tatacaggat tattatttag aattgccgga gagaagccca ctatcggaaa ttgatgattg
    11041 gctggaaaca atggagatgc catataaatt ttttgagaat actttttggt tgagtggagt
    11101 ttatgaaaaa gcatctcaga atggaatagg agtacttctt agtggtcaaa gaggtaattg
    11161 gacagtatcg tggggaccta ttttagatta ccaggcaatg ttattgaaaa agctacattg
    11221 gattcgtttt tatcgtgaac tacatttata tagtagaaat ataggagtga aaaaatcacg
    11281 tgtttttgaa gtggtaagac gaaaggcatt tccatttttg catcagttac ttttttcagg
    11341 gaaacaagat gcaaattccg caataattaa tccggaattt gcaagggaaa tgaatgtttt
    11401 tgacagactc agagaacaag acatcgatat aacaggcacc tctatctcta atgcatatga
    11461 catgaaaaga gaacagtttg aaaaaccata ttattggagc ataaatggaa cgtatgaaac
    11521 gaaattatca ttacgttatg ctttatggga tcgtgatccc acaaatgact tacgattgat
    11581 tcaattttgt ttgtcagttc cagaagaaca gtatgttcaa aatggtttgg atcgagccct
    11641 gatccggaga gccacaaaga atttccttcc tgataaagta cgattgaatc aacgggttcg
    11701 aggtattcaa ggtgcagatg gtgtttaccg catggctcct ttttggaatg aatttattga
    11761 ggaagttgaa gaacttagtg tagatccagt aatttctgaa tttctaaatg tcgaggtaat
    11821 taagaaagct atctcaaaaa tttgtaaaga acctcgacca gaatatgcat ttgatgtaga
    11881 ttttagaatt ttaatgcgta gcttaatctt ctatcgattt ataaaaaaag caatgtgaaa
    11941 ggaggtgata cgtatgaaaa aggaatggaa acaacctgta ttagaagtac ttaatattaa
    12001 tatgactatg gcggggcctg ggcataaata tccagatgct gttcaacctg acccagatga
    12061 tccagtgaag tacagttaag tcattggaaa aataaagctc ttatatagct ttattatata
    12121 agagctttca aaaaattgac aatgtggggg ataggatgtt tgattctatg gggaatgtgt
    12181 tatatcaagc cttcgggtta aaaatagtaa gtgaaatccc attacctgaa ttgtctcagc
    12241 tgaatgaaaa aaaagagatg gcggatgttc aagttgaaat aactgatttg tcagaacagt
    12301 ggggtgaata tagcgcagaa aagcaaaaaa cgatagtagt ggaggatgat atagttatgt
    12361 ttcatgttcc tcaaactgca atattcgcta tacaatcagg tgagaaaatc accttttcac
    12421 ctatggcaaa tgcagaagaa gataaaattc gactatatat tttgggaact tgtatggggg
    12481 cgcttttaat gcaacgtaaa atactcccat tgcatgggag tgtaattgct atagatggga
    12541 aagcatatgc attaattggt gattcaggag ctggaaaatc aacgttagcc tcggcttttt
    12601 tgaataaagg atataagctt ttaagtgatg atgtagttgc tgtgtccctt ttgaataaaa
    12661 atactgcaat agttcatcct tcttacgcac aacaaaaatt atggcaagag agcataaatg
    12721 agttaggaat ggaagtagcg caatttagcc ctttatttga aagggaaacg aagtatgctg
    12781 ttcctgtgaa ttctcaattc tttcctgatc cattacctct tgctggtgtt attgaattag
    12841 taaaaacgca gggagaagat atcgagatga cccgtataga agggctcgca cgcttgtata
    12901 aattataccg ccatactttt aggaattctt tgatttctaa attaggattg atggaatggc
    12961 attttgaaac ttcatctaat attgcaagtg gaatggaaat atttcaagta agccgcccgg
    13021 cttcaagatt tacagctcat gagcttgtgg aagttatttt aaatactata cagaaaggga
    13081 gtatggttga tggttgtcca ctcgagaaaa atatcattag aacataacgt tgtccaaagt
    13141 aagggtaata tagtaagcga tatggatgga gaaaaagtta tgttaaatgt ccagaaagga
    13201 aattactata acttaggtga aataggcgga gaaatatggg agcttattga aaagccaata
    13261 ataattaatc agcttgttac tatgctagta tctaactatg atattgaacg aaaagattgt
    13321 gaagagcaag ttctttcctt tttagagtgt ttgtttcaag aagggttaat tcaaataaaa
    13381 gatcagccta atagatagat tcgtaatttc aaaagaactg ttaggaaggg attaataaat
    13441 attgtgaaaa ggttaaggat gtttttatca ctaaacatga aaacaaagct cttattttta
    13501 gaggctttta tttttttagg atgggcacgt gtactaaaaa atattacatt ttccaaagtt
    13561 gcaccttctt taggggatta catgagtgaa acctcaagta ctcatattca accgcacgga
    13621 gatacgctaa aaaaggtgtc cgaagcaatt tctattatga gtcgttatac tttttgggaa
    13681 agtcaatgtc tcgttaaagc tatagctggg atgaaaatgc tcgaaaaacg tcacattgag
    13741 agtactcttt atttaggaac tgctaaggat agtcatggtg aattaattgc gcatgcatgg
    13801 ttacggagcg gttcttttta tgttactgga tcagaaggaa tggagaaatt tactgtcgtt
    13861 ggatcatttg caaagaggtt aagtgaggac actattaaag gagagtaaaa tggagaaaga
    13921 ttttggtctt aatgtagagt tcatgtctaa ggaattgaaa cttctttttg caattttgaa
    13981 gttacaagat gacgaaacaa tgcaaactta cagtaatgaa tggttttcgg atattgattg
    14041 ggaagtattt cttgagcaag ccgtgcatca tcgcgtttat ccggtgatat atcaaaaact
    14101 taaacaggtg gacaaggagc tgattccttc acatattgta caaaccttga ctagaaaata
    14161 taaaagaaat acatttcaaa tgctttattt aagtgctgaa atggaacgaa taaataaatt
    14221 atgtaatgaa aatgagattc gtacgatttt tctaaaaggg cctgtactat ctcaggactt
    14281 atatggagat ctttctttac gaacatcctg tgatttggac gttctcatcc ctattcaaaa
    14341 tttagaaaaa gcagaaaaac tacttttaga gcaagggtat gtgaaagatg attatattca
    14401 aacgatatta agtgattgga aatggaggca tcaccatata acatttttcc acccaacaag
    14461 gcggatcaaa cttgaaattc attggagatt aaatcccgga ccgggtaagg aacctgggtt
    14521 tgaagagctt tggaagcgaa agagaaaaag tacacttacg agtaattcgg tatatatgtt
    14581 agggaaggaa gacttatttt tatttcttgt atctcatggt gccagacatg gttggtccag
    14641 gctacgttgg ttagtagaca taaaaaaaat tgtcgatcaa gatcttaatt ggagtgagat
    14701 tcataaatta atgagaaaat atcaaatgct tcatttagga ggacaagcgt taattttggc
    14761 atctcaattg ctaggtgtac gactagatga aagaatgatg gaattagtaa ctaaaaaaca
    14821 ttcaaaacag ttagcgcaag aagcgttgtt ttatttcaag caaatgataa acttgcatac
    14881 cgaccctgtg ccagaagaag tacttgctta tcatagtcga catttatttt cactaatgtc
    14941 taatcagcaa aagattttat atattatgag ccaactatat ccttatccaa ttgatgcaaa
    15001 aacattgccg ttacctaaat tccttcattt tttatatttt cctttacgtc cgtttctatg
    15061 tctttggagg aaaacaaaga agcttgcttt gttatagggg gaacatcgat gaatcatatt
    15121 atatatttta tcaagaaatt atattcttct gcagggaaaa ttctgtatgt gaatttgttt
    15181 ggtatggttt taataagttt acttgaaggg ataggtatta ttttattaat tcctatgata
    15241 agtatgactg gaataattaa tataggtgag gagactgctt ttattgcacc tgtctataga
    15301 tttttgcagg atttccctaa aacaacaagt ctaatttcta ttttaggtat atatatacta
    15361 atagtgttag gtcaaaatct attacaacga aacataacgc taagggatgc gagaacgcaa
    15421 caagctttcg tacgagaatt aagaatagaa acatatagta tgattctaaa agcgaagtgg
    15481 agtttttttt tagagaaaag gaaaacaaat ctaataaata tattaactac agaattagct
    15541 cgcgtaagtt atggggttaa tttaatttta caattgttag ctgttattct gtttacattc
    15601 atacaggtgg ggcttgcgtt tttattatct ccccaaataa ctatatttgt tttggtcttt
    15661 ggcttattat tcttagtagc ttctcgtgct tttataaaaa aagcacgaat actaggcgtt
    15721 aagacctcga aattagcaca agactatctt tctggtataa cagatcattt taatggaatt
    15781 aaagatataa agagtaatac tttggaagca tcacgtttag attggttaca atctataaca
    15841 gaaaagatga gtaatgaaca aatggagtat atgagaataa ggtcgaactc tcaattgttt
    15901 tataaagttt caatggctat tttaattgca ttttttatat tattatcagt aagtatattt
    15961 aaagctcaac ccacccaatt actattaatc atactcatct tttcgagact atggccacga
    16021 tttatgacaa ttcagtcaaa tttagaacag cttgctgcaa gcattcctgc ttttaagtca
    16081 ttatgggaat tacaagggga atgtaatgaa gcaattgaaa tgcaggatat acatcagcaa
    16141 aaacatataa agccgatttg tatagagcag ggtattgaat gtaagggtat ttattttcga
    16201 tataataaga aggagcattt gtatgcactt caaaatatta atgtgaaaat accaatcaat
    16261 agtatgacgg ctattgtggg acattcggga gctgggaaga gtacattaat cgatgtttta
    16321 atgggattga ttcagccaga gaaaggtcaa gtattaatag atggaactcc tcttacaagt
    16381 gaaaatttat tgtcattgag acgggctatt agttatgtgc cacaagatcc ttttttattt
    16441 aatgcaagca taagagaaaa tttattgatg attgagccga atgcgagtga agaacaaatt
    16501 tggactgcat tagattttgc ggcggcagct gaatttgtac gaatgcttcc aaaagggctt
    16561 gatactctca ttggagatcg tggagtgaga ctttcaggtg gtgaacgtca acgacttgta
    16621 ctagctcgag ctattttaag acaaccatcc attttagtat tagatgaagc tacgagtgca
    16681 ttagatactg aaaatgaagt aaaaattcaa tcagcaatag aaaggttgaa aggaacgatg
    16741 actattgttg ttattgcgca tcggttatct acgatccgca atgcagatca agttattgtt
    16801 ttaggaaaag gtgagattgt tcaaaaaggt gaatttaatc aattggctaa agagagaaaa
    16861 ggtgtatttc gaaatttatt agggtcacaa atggaagtgg gttcatagag gagaaagatt
    16921 gaatgaaatc ttgtagtatt gtaattcgag ttgaatgaaa gccgggataa tggtcagtta
    16981 caacagatct tattcgggct tctatatttg tgttttctaa atttagggaa taaatataat
    17041 tcagtacctt gcaataaaca atactaagtg gtatattatg gataaaatag ctaccgttta
    17101 ttgaacagta ctaaaatgag aaagggggat tgtccttgaa cgttcagttt aaaaaaggtg
    17161 tgttagaact gtgtgtattg gcacttgtaa aacgtaagga ttgttatgga tatgaacttg
    17221 ttcagcaaat ctctaataaa tttttaatat cggaaggttc tgtatatccg ttattacgtc
    17281 gtttaacgaa agagggatat tttcaaacgt atttaaaaga atccacggaa ggaccgcccc
    17341 gtaaatatta tcaactaaca gagcaaggag agatgcaact tactttatta gtaacagagt
    17401 ggcgtgattt tgctaaaggt gttcaagaaa ttattgaagg ggtggaatgg gatgagtaaa
    17461 gagcagtttc ttaaagaatt atcaagtcat cttagaaagt taccagaaga agagcgacaa
    17521 gatattttat ttgattatga agagcacttt cagtttggga tggaagaggg gaaaactgaa
    17581 tcagaaataa taaagggact tggctctccg aaagtaattg cgaaagactt acttgcgatg
    17641 tatcgatttg atgaaatgaa aaaagatccg tcgacttcaa atgtgacaag agctgtcatg
    17701 gcagcggttg gacttagttt gtttaatttt attattgtgt taggcccgtt agttgcaatt
    17761 atagctttta tattttcctt ttgggtcggt gggattgcta gtgtagtgac accatttttc
    17821 gttattgtaa aagtatttat gggcactttt atatggttgg atcttttcgt tagtataacg
    17881 tttgtcggag taggtttgtt gttatgtatt gtagcttatt atagtacgaa gtggtttaaa
    17941 agattatgtg tacgctatgt agtctggaac ttcaaaatga taaaagggga gtagatgatg
    18001 aaaaagatat tattagtagc tatcgcttgt atcattattg gagtaatagg gatttcacaa
    18061 acatatgaaa aagcagtaca aactgcagag aaaggagata aagaggacgt aattaaaaac
    18121 gaaacgctaa aaaatgtaga agttaagtta gatgctggag atattgttgt ccaaaaatct
    18181 cctgattcct ctttttatgt aaagcaaaaa ggagacgtaa gtaaacagga gattcgtatt
    18241 gctgaagatg gtgatacatt aaaaatcata ggggaaatag aaaaaggtgt ttcatttgat
    18301 ttttcatttt acaatttcgg atttcaaacg cctacattga ctatattagt acctgaacgt
    18361 tcttatcaag agataaaagt aaattcatcc gctggacaaa tagaaataag taatgtgaaa
    18421 agtgaccgcg taagtgttga aacactcgcc ggagaagtgg atttgaaaca tgtaacagca
    18481 aagagtgtgg aggggtctac aaaagctggt gaggtgaatt ttaaaaaagt aatagggaaa
    18541 gtaacagcaa aaacggctag tggggatata gatattattg atcatgattc taaatatgat
    18601 ttagaggtaa gttcaactgc tggagatgta gatattactt tattggaaaa accacaagat
    18661 gcagttataa ctgggcaaac tgctgctgga gacgtgacaa tttttaatga agacaataaa
    18721 aatataacga ttggtaatgg tagtaaaaag attagcggta aaaccgctgc tggagatgtt
    18781 actattgaaa cgcgttaata attaatgaaa cgcattcttt tgaatgaacg gaaatctatc
    18841 aaaatataaa aagaagataa ttacctatat aaataaggga attatcttct ttttattatt
    18901 tttaatgtaa atcacgatat acgccaatta cttttccaat aactgacact tgttttaaaa
    18961 taataggttc tagtgaagag ttttccggtt gtagacggaa atgatctttt tctttataga
    19021 aacgtttaac agttgcttcg ttatcttctg ttaaagcaac tacaatttca ccgttgtatg
    19081 cagactgttg ttggcgaaca acaactaaat caccatcaaa gataccggct tcaatcatgc
    19141 tatctccaga aatgcgtaac ataaacactt gatctgctcc agcaacgata ctagctggaa
    19201 gtgggaagtg atcttctaca ctttcgactg ctgtaatcgg taaaccggca gtaacttttc
    19261 cgatgattgg aacttgaata acagattgtg tttccgttcg gttgtcacct aaaatttcaa
    19321 ttgcgcgtgg ttttgttgga tcgcgtcgaa tatatccctt ttcttctagt cgtgataaat
    19381 gtccgtgcac tgtagaacta gaagcaaggc cgactgcttg accgatttca cgtacggaag
    19441 gtggatatcc tttttcttgt acttttagct taataaagtc gagaatgtct tgctggcgtt
    19501 tcgttaactt ttccatgttt tctaacacct cgttttcttt catttttctt attattaagt
    19561 ataacatgcg aaaaaacatt ctacaaacat aagttcgaac gaaaggcaaa tttatgatac
    19621 actataagga aaatatagtg agaaagaagg gttcaaaatg aatgcaatta tttatgcacg
    19681 tgtgagcaca acaaaagaag aacaggaaac atcattattg cgtcaaaaag atgaattatt
    19741 gcatttagct gagcgctatc aaatggatgt tacaaaggta attgaggagc aggctagcgg
    19801 ttatacaatt gaacgtgatg gcatattaga agtgctagat acaattcgag atgaacaagt
    19861 tgatgtacta cttatacaag atgaaacgcg tcttggtaga ggaaatgcaa agattgcatt
    19921 aatgcattgt ttacataaag aggggataaa agtttataca cacacacata gtggtgaatt
    19981 acagctttca gattctgatt cgatggtgct aaatataatt gggatcgttg aagagtatca
    20041 aagaaagatc cacaatttaa aaattaaacg tggcatgcaa agagcagtgg agaaaggatt
    20101 tcgtccagaa aataatttga aaaatcgtca tttaagcgta ggacgtgaga aaaaagaagt
    20161 gccaattgag gaaattgtac gtttgcgccg gaatgaatta acttttgaag aaattgcagc
    20221 aacacttcgt ggttttggtc atgatgtttc aaaagcaact gtacatcgaa ggtatgtaga
    20281 atatacaaag caattgcttg ataaagagga ctaactattg tatgataata atcagttttg
    20341 agtagaaggg ggattcgaga tgccaagtca agaactcatt gaacgcatta acttcttagc
    20401 gaaaaaagca aaagctgaag gcttaactga agaagaacaa cgtgagcgcc aatcgcttcg
    20461 tgaacaatat ttaaaaggat ttcgtcaaaa tatgttaaac gaattaaaag gaattaaagt
    20521 cgttaacgaa gaaggcacgg acgttacacc ggcgaaatta aaagctttaa aaaagcagga
    20581 taatgcaaaa ttaaattaaa agatgggcat agcccatctt tttttatttg ttaaaattgt
    20641 tatttaataa ctttccagtt ttcatttttc gttgcttcta tccttttatg cttcaatata
    20701 tagttagcga taagttcaga catatctgtt ggtatgtctt ttactactgg tttattttga
    20761 aacataaaga agttcccgcc accgcttgca cgataattat tcataacaac gtcatattct
    20821 tcattcatat taagaggagc gcctttatac tgcaaagact ctactctctc tccaattggt
    20881 tttgaaatgt ttaatacata cgaaatccct tcccacatat cgtaattata gtgttgtggt
    20941 tttggttcta tataggtagg gtttacgatg atggttccat ctgcttttaa tgtgaaataa
    21001 gaagcagaga gttcgagagc attttttata tccgctccgg ttattctaat tacttttaat
    21061 gtatttggat aaatataatt agaaacgatg tcacgcattg ttacatgttt agggaaacct
    21121 ggagatgtat tatgaaacaa acttgtacaa gaaattgaaa cattagctat atccatctgt
    21181 attttattta tgaattcaat aaaaggatgg tcttgcaaac gtgtttgcat agcatcggaa
    21241 atttgcatat ccccataaat tattccaata ggtttatcaa gccaattttg tgttttctct
    21301 tcataattgg caaccaagga aagaacatct tggtctgccg caattccttg tacgggcaat
    21361 aactctgaat aactctcttt tttcacccat ttttgttctg ctttttcgaa tgttactgtt
    21421 acttttccaa ctgagtgtcc attgcatccg gtctgtaaaa ttgttacacc attaatcacg
    21481 gtgtgagcga tttctcggtg ttggtggcct gttagtaaaa tatctatgcc ttcaatttca
    21541 tggcacattg catatccttg gttttcacct gttaaaactt cagtcggtac tccggtttgt
    21601 aaatcacgtt caaatccccc gtgataggct acgactagta aatctggttt ttcatgttta
    21661 cggatgtaag aaacccattt ttttgttgtt tcaaatgcat cttcaaattg taaatcttta
    21721 atatgatgtg cttgttccca atgggggatg taatgcgttg tcacccctaa aatagcaatt
    21781 tttatatttg attcaatatg ttttattata tatggttttc cgaaataagg ttcttttctg
    21841 tttttatcta aaatgtttgc tgatagataa ggggaatttg cagtagtcac agcattattt
    21901 aatatatcca ttccgtaatt aaattcatga tttccgataa ttgcaatgtc atactctaag
    21961 tagttggcta ataaggacat tgggttttcc atatcttttt cgtatgtagc gtaatgataa
    22021 gtaaatggtg ttccttgaat gaagtccccg ttatcaatca gaagaacgtt tgcattttga
    22081 gaacgttctt tttttatgag agtagaaatt ttagctaaac caatttctgc tttggagtta
    22141 tcttggtagt gaattggata cacagtacca tgtacatcgc ttgttaataa aatatttaaa
    22201 gttacaattt gattttgatt caacgccatt caccttttct atagttatct ttcaattaat
    22261 catatcaaat atatgaaaag aattttaatg tgaatgtata gaatatgtaa agattctgta
    22321 aataagcaat tatttgtaaa aatatgtgat atatttcttc atgtttatgg aaggttattt
    22381 tataacaacg aaaaatggag gcattaacat gttgaaaaaa gtttttgcaa tgagcacaac
    22441 agttgtacta gcagcgggat tattaagtgg atgtggaacg aaggaatcaa gtgcaagtaa
    22501 aaatgaagat acgaaaaaag gttatgtacc gaagacacta aatgttcaat ttgttccttc
    22561 tcaaaatgca gatacgttag aggcgaaggc aaaaccattg gaaaagctat taagtgataa
    22621 attaaacatt ccggtaaaag ttagtatttc aacgaattac aatacaattg tagaagcgat
    22681 ggcatctaag caagtagatg taggcttttt acctccaaca gcgtatgtgt tagcgcatga
    22741 gaaaaaggct gcaaacgtaa ttttacaggc gcaacgtttt ggggtagatg atgaaactgg
    22801 agctcccaca aaggatttag tagatgttta taaatcagag tttgttgtta agaaagattc
    22861 taatattaat agtgtaaaag atttaaaagg taaaaaaatt ggctatcaag atgtaacatc
    22921 atcagcgggt tatgtatggc ctgcggctgt attgttaaaa gagggaatcg atccgttgaa
    22981 agatgtgaaa cctgttacat taaaaggtca tgatcagtca cttattgctc ttttaaatgg
    23041 tgatgtagat gcagctgttg tattccaaga tgctcgtaat attgtaaaaa aagattatcc
    23101 gaatatattc gatcaaacga aaatagtaaa atttacggag aaaattccaa acgatacgat
    23161 ttctgtacgt tctgatttag atgcagagtg gagcaagaaa ttacaggatg ctttcattga
    23221 aataggaaag aatgaggaag ggcacaaaat cattaaagaa gtatactcac atgaaggata
    23281 cgttaaatct gatgatagta aatttgatat cgttcgtgaa tatggaaaga aagtgaaaac
    23341 gcaataatac atatggaaat ggcgactaac tggaaagtgt gtgatttcag ttagtttgcc
    23401 gtttttcagt tattgataat acatagaagg taggtaagat gtgtgataga gtttcgaaat
    23461 gtttccaaag tgtatccgaa tggtacaaaa ggattgaata atataaactt gaaaattcaa
    23521 aaaggtgagt ttgttgtaat ggtcgggcta tccggtgctg gaaaatcaac acttcttaga
    23581 ttggtaaatc gccttcatga aatcacagaa ggagaaatca ttattgaagg ggagtctatt
    23641 actgctgcaa aaggaaaagg attacgacgc atgcgccgag atattggtat gatttttcaa
    23701 agctttaacc ttgtgaagcg atcaacggta ctgaagaatg tattagctgg gcgggttgga
    23761 tatcattcta cattgcgtac aacgttaggt ctgtttccga aagaggatgt ggagcttgca
    23821 ttccaggcgc tgaatagagt gaatatctca gaaaaagcat atgcacgagc tgatgaatta
    23881 tcagggggac aacagcaacg tgtatcaa
//
