LOCUS       NZ_CP035999            47011 bp    DNA     circular CON 10-DEC-2024
DEFINITION  Bacillus mycoides strain BPN37/1 chromosome, complete genome.
ACCESSION   NZ_CP035999
VERSION     NZ_CP035999.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus cereus group.
REFERENCE   1  (bases 1 to 5322329)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5322329)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 108.48400000000001x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739505.1-RS_2024_12_10
            Annotation Date                   :: 12/10/2024 03:54:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,286
            CDSs (total)                      :: 6,132
            Genes (coding)                    :: 5,884
            CDSs (with protein)               :: 5,884
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 248
            CDSs (without protein)            :: 248
            Pseudo Genes (ambiguous residues) :: 0 of 248
            Pseudo Genes (frameshifted)       :: 114 of 248
            Pseudo Genes (incomplete)         :: 146 of 248
            Pseudo Genes (internal stop)      :: 66 of 248
            Pseudo Genes (multiple problems)  :: 68 of 248
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:59:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 388191
            Orig. end                         :: 435202
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035999.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..47011
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..47011
                     /SMILES="NC([*])C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47011
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27011](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..27011)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(138..905)
                     /locus_tag="EXW27_RS02135"
                     /old_locus_tag="EXW27_02160"
     CDS             complement(138..905)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168306.1"
                     /locus_tag="EXW27_RS02135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02160"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_016127048.1"
                     /transl_table=11
                     /translation="MTKLQDQLFTRLNLEKRTEIKFEELSTILFVFAHTIPFENLNVIA
                     SNANTISMKNLQEKILTSSRGGLCYELNTLFYYFLKDSGYDVQLALGTVYKNDINAWAL
                     EDGHITIILNYENVRYLIDVGIASLVPLVPVPFTGELVSSKNGSYRVRQKDTSKGNYVL
                     ERIDVDGEWKVCHAFYKHIIDETVVNDVQRRVIEDEKSIFNKGPIAVKLTNFGHVSLTN
                     TILTEIIYGEKTKREITENQYKELLYTLFAIEL"
     gene            complement(1096..1464)
                     /locus_tag="EXW27_RS02140"
                     /old_locus_tag="EXW27_02165"
     CDS             complement(1096..1464)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403474.1"
                     /locus_tag="EXW27_RS02140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02165"
                     /product="DUF4180 domain-containing protein"
                     /protein_id="WP_002127579.1"
                     /transl_table=11
                     /translation="MEIKKVVIGGINIAVVRNDTVLISDVQSALDLMATVQYEADSKRI
                     AINKSLISESFFDLKTRLAGDILQKFINYSVKIAIIGDFSMYTSKSLKDFIYECNKGKD
                     IFFLATEQQAIEKLSSLK"
     gene            complement(1636..2313)
                     /locus_tag="EXW27_RS02145"
                     /old_locus_tag="EXW27_02170"
     CDS             complement(1636..2313)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002032335.1"
                     /locus_tag="EXW27_RS02145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02170"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_147740394.1"
                     /sec_met_domain="HAD_2 (E-value: 4.6e-31, bitscore: 106.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFDLDDTLLDRDKAVDKLFSIILEEFYGDVEQHAVKNEMLQKFK
                     GYDKKSYGHSDKVKVLESFFDEFPPKYRLPRNYIQDFWNNNFPKCFSINQKTINIINTI
                     KSHIKVGIITNGSTQRQKEKIINTNLNRYFDTIIIFEEAGFSKPDKLIFELALNKLNVQ
                     SEDVLFVGDDLEKDIAGCQNANIKGIWFNPNMIKNNTDTKPYAEITSFDNLLSYCGEIN
                     FQK"
     gene            2777..3442
                     /locus_tag="EXW27_RS02150"
                     /old_locus_tag="EXW27_02175"
     CDS             2777..3442
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002200383.1"
                     /locus_tag="EXW27_RS02150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02175"
                     /product="response regulator transcription factor"
                     /protein_id="WP_000800741.1"
                     /transl_table=11
                     /translation="MKNYHILVVEDDQEIQELIKQFLMTQQYTVVVASDGLEGMTQFNK
                     QSFDLILLDVMMPNLNGFEVSKMIRSQSNVPIIMLTALEEEEDQMKGFDLGIDDYITKP
                     FSFHVLIRRVEAVLRRSYDKNVNNHLVFKEVRIDVDAYRVYVNDVEILLTTKEFEILQL
                     LFQNERKVLTRENIVEKVWGYDYFGETRIIDTHIKNLRKKLAIPYIKTIKGIGYKIDE"
     gene            3435..4907
                     /locus_tag="EXW27_RS02155"
                     /old_locus_tag="EXW27_02180"
     CDS             3435..4907
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084875.1"
                     /locus_tag="EXW27_RS02155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02180"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002168308.1"
                     /transl_table=11
                     /translation="MNSIVKIMKMKQITYKLFMTTSLILLSFAVLIYLTLYFFLPTFYE
                     QYKTDQLQTGIKEIIDKSKDLTFQDAIPLFDEYAKKNNAMLYLQNNEGIIKYSPSFSFT
                     QNGSQTTVVTRATRFENAGTLSNSYNVTKPIQFQDGSLTLIVFATFQPIDEASQVLVRF
                     LPYISIIVLIIGVGSAYFYSRFITKPLIYINEGAQKMANLDFSEKIEVRSTDELGELSN
                     SLNDMSINLQQAMFDLKKANQQLKNDIEKEREIETKRREFFAIVAHELKTPLTVMKGYL
                     EGMIYNIGPYQNRDQYLKKNHQIIESMEQLVREILSMSKLEQHTFKLKVEEVNLSKLID
                     TITKDLEFFASQKSIQIIKEIDSDLSVYTDRVLFEKACKNIIHNAVMYSPHNEKVYIKL
                     SEDSKQGQIKMQIMNTGVNIKEEDIQQIFKPFYRIEKSRNRNTGGSGLGLYIVKQILET
                     LDIKYSIKNMERSVQFSMNIPLSKQKTNKLPS"
     gene            complement(4965..6257)
                     /locus_tag="EXW27_RS02160"
                     /old_locus_tag="EXW27_02185"
     CDS             complement(4965..6257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002165714.1"
                     /locus_tag="EXW27_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02185"
                     /product="hypothetical protein"
                     /protein_id="WP_078179087.1"
                     /transl_table=11
                     /translation="MLIYIVYGLQISKGFEGYWPSILFYTTYMTGVFIWIPIVNKAGIH
                     RSLYWTVSILIVSLLSVTFFGWSSRWLEISALVSGFAVSTISTMTSTLLFLHVEGGGKV
                     YNKNQQAIIIGIVFLLLIIVLLAISFLSPPLITCIYGICLISILFAIKKMPRTELAKGL
                     LPISIVSVVGKFLFVSMLILLIRTSRNINNEQYIFYFFLLSIALICFMFLSLLKGKFFH
                     KLSSSLPIRLKAESFLLGLGNGYLFLMGIFYSFTFYNMLTCIFIVVGPYLLGILMSIFL
                     DIKAAKKVNPIHLFLVSTLIMIFGFYSPIFIVLSVTFGSYAINSISSQNNMKVYMVNAT
                     HRELSLLIYTTWRNMGNIFLQFFTLIVIVGVGVFYDVEWSQLFQTIVGKGQMQIEGLSV
                     QRLMFMLAICCWLGMVGLGMWIGKKANPNIA"
     misc_feature    6631..6645
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.36"
                     /tool="antismash"
     gene            6727..7662
                     /gene="bla"
                     /locus_tag="EXW27_RS02165"
                     /old_locus_tag="EXW27_02190"
     CDS             6727..7662
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127046.1"
                     /locus_tag="EXW27_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02190"
                     /product="class A beta-lactamase"
                     /protein_id="WP_016127046.1"
                     /transl_table=11
                     /translation="MIVSKKFFHIAHYKKMLPVVLLSCATLIGCSNSNIQSAPPKQTKQ
                     ENTSNHSFVKLEKEYDAKLGIYALDTGTNQTVTYRSDERFAYASTHKALAVGALLQKKS
                     IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGPS
                     EFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN
                     FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSN
                     HAKEDAKYDDKLIANATKIVLDALKVTNKS"
     gene            complement(7903..9063)
                     /locus_tag="EXW27_RS02170"
                     /old_locus_tag="EXW27_02195"
     CDS             complement(7903..9063)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739710.1"
                     /locus_tag="EXW27_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02195"
                     /product="Ger(x)C family spore germination protein"
                     /protein_id="WP_016127045.1"
                     /transl_table=11
                     /translation="MKKNKRIVIFLFMMCTFLTGCWDQRELHHVLYINSLGIDFKDNNY
                     IIRPQFINFSNIAKQEGSTTRNYSQAYIGKGKGPILDEAAFDFYKGAQQEISWEHLKTI
                     VVTERFLKHGDLNQFNDFFSRFFQFRDTMWIFGTKEPLENILANNNILNISQLYTIINL
                     PKEITKQYTIIDPLPLYKFQRNYYEPGMTTRIPFLATTKTYWKKGHTSFPMLKFSGYGF
                     INDKSYINHLNSHDIAGVRWTDENTKRAPLLLKFNKKIIGHIVLKNPKIDTKHFIKNGK
                     LRMLMNIHFDADIFQLINSMPVNDIKKIAEDQVEKEIKKTYRKGIERGIDTYQLSHSLY
                     RQNSKLWKRYKKEGGISLQNKELDLNVSINIATNGKSKNMRNMIEH"
     gene            complement(9050..10528)
                     /locus_tag="EXW27_RS02175"
                     /old_locus_tag="EXW27_02200"
     CDS             complement(9050..10528)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016091415.1"
                     /locus_tag="EXW27_RS02175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02200"
                     /product="spore germination protein"
                     /protein_id="WP_016127044.1"
                     /transl_table=11
                     /translation="MNKQVEINEKIILEWFEGCNDVKVIKRELDEKEKRNSVLFMYCQN
                     LIDNTKLKQATSSHVCKELSSNSIEEFNLSTLIPQLSVKKLDMVNSNETISQIIFEGNL
                     LIIFEESKHGYIVDIAQIPTRSVEQTNTEMTIRGGRDGFVEELNTNIGLIRKRLKTSSL
                     SYEEFIIGERTQTKVALLYLKDVASQDIINQVRLKLRQIKIDGVVSSAQIEELITNNQF
                     SVFPLVEYTGRPDYTVNCLLYGRFILLVEGSPTATIAPVTFPFFVNTSEDQDLFYIFGS
                     FVRLVSLLGIAISIFLPGIWIALITYHPDQIPYTLLATLSLSREGIPFPAPLEGIIMMT
                     LFEILRQAGLRVPAVFGQTLSVVGGLIIGQAAISAGIVSASMVIIIAISVVSTFALTNQ
                     SVTGIISILRYVVFLVSSLLGIVGFIFCVLVMVIHVVNLRSFGVPFFTPYSPPVFKSML
                     AATFRLPFTYMKKRPKELHTQDNTRKRESTDEEK"
     gene            complement(10585..11664)
                     /locus_tag="EXW27_RS02180"
                     /old_locus_tag="EXW27_02205"
     CDS             complement(10585..11664)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166383.1"
                     /locus_tag="EXW27_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02205"
                     /product="endospore germination permease"
                     /protein_id="WP_016127043.1"
                     /transl_table=11
                     /translation="MTKQTITLFQVSMILIGSIGIINHVIMIPMLLDTSGRDSWISIIL
                     VSIIYLIWISLIFIIYRNIKNEHLFSWLKNNFGKLSVYPIIFIVVIYLITIGVVALKET
                     LTFFSFYLPETPHFVLGILFSMICLYNATRGIQSIALTTGVLLPIVFLLGFFVMFANVP
                     HKDYSLLQPMMENGMKPVLKGMVYPAAGFLELIFILFLQHHICSKVKLYQLIALGMVII
                     GITIGPVMAAIIEFGPFVAANQRYPAFEEWRLVSIGRYIENLDFLSVYQWLVGIFIRLS
                     LVVFLIPDLLSITNQKTRNGIMFAILSCILLISILPISDSSFYWFVSQIILPVSALGLF
                     LFSILLIVFVWVAKFKKSS"
     gene            complement(12106..12783)
                     /locus_tag="EXW27_RS02185"
                     /old_locus_tag="EXW27_02210"
     CDS             complement(12106..12783)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002085362.1"
                     /locus_tag="EXW27_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02210"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003189466.1"
                     /transl_table=11
                     /translation="METILQFKNLDYYYESNGKKVAILENVNFSFQKGHFYTILGPSGS
                     GKTTTLSLGCGLDIPKNGYVLFNGKDIRKIGLDRYRNQNVSVIFQSYNLITYMSALQNV
                     LTAMEITGVKVQNKTARALELLEKVGLTEVEAKRNVLQLSGGQQQRVAIARALSCNVDL
                     LIADEPTGNLDEETAMDIIELFQELAHKENKCIIVVTHSQEVAKKSDRAVYLSKKKLVV
                     NEI"
     gene            complement(12795..14225)
                     /locus_tag="EXW27_RS02190"
                     /old_locus_tag="EXW27_02215"
     CDS             complement(12795..14225)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016081356.1"
                     /locus_tag="EXW27_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02215"
                     /product="ABC transporter permease"
                     /protein_id="WP_147740393.1"
                     /transl_table=11
                     /translation="MNFMKRAILSMKKRVGTSLILMAIFLIVTNLVLAGFTIQNASKKA
                     ADAARKKLGADVTLSLDFDKLGQQARETGEMPNPPKLNTKEADQLAKSKYVKDYNYITS
                     TLGISDGLKLVGASEGEEEGKGKAGMAAVRGGSGSGTEIDMNSSFMIEGVRKTALQESF
                     KNGKSKITDGKPITEQMKDQNVALMEKRLAELNNLKVGDKVKVQSGDKKETLEVEIIGI
                     YETNEQAMGQQAPPIMDPANKLYMPHSTMKKLEIDQGISSIQVVYFLKDPQNIEAFKEE
                     AKKSDIDFNYYKLDAHDSLYKQMIGPIENISSTSQMIIYIVSIAGAIILGLIIMLSIKA
                     RRKEMGILLSIGEKKWKLMAQFVVEVVCIAILAFGLSITTGAKISQFIGNNLLSSEIAT
                     AGEETNTSQNGTVMVAGPGGTVQNQKEDPIDKINVSVKGEDVGKMGGIGLAIAILATLL
                     PALSILRLNPKQILLKDE"
     misc_feature    complement(14189..14203)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 24.13"
                     /tool="antismash"
     misc_feature    complement(14355..14369)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            14739..15200
                     /locus_tag="EXW27_RS02195"
                     /old_locus_tag="EXW27_02220"
     CDS             14739..15200
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002085364.1"
                     /locus_tag="EXW27_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02220"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_002032325.1"
                     /transl_table=11
                     /translation="MTETITFRIATADDLDEIVKMLADDVLGNKRERYETPLPDSYIRA
                     FHAIDCDPNNELIVACDGTEIVGIQQITFTPYIVRQGGWRATIEGVRTASSKRGKGIGS
                     KLIKWAIQRAKLRGCHLVQLTTDKERQEALHFYKKLGFKDSHEGLKLFL"
     gene            15595..16596
                     /locus_tag="EXW27_RS02200"
                     /old_locus_tag="EXW27_02225"
     CDS             15595..16596
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577726.1"
                     /locus_tag="EXW27_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02225"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_078179280.1"
                     /transl_table=11
                     /translation="MIFSKLIDRYALYDLHKKRSVKFQYTSLSNTSLYIKDIEFFYKVK
                     PSHIHFNIKHLKQEKEYMVGQFKYKSSVQSGDSRNDSVTRELFLHKNENAPHVIFVHGW
                     RMDSNERVKKIFHDHMTNLKWNMYYFTLPYHFDRKPNQSLYSGEYMVSANVERTVEATR
                     QAVADLRTLIKWIKENKNGPLILIGISLGGVITNLTSLVEPEIDVLASIFYANRLSYSI
                     WKTNPGNFIREDLEHHGVTYDDLIAYWKITEPSQALPKVKKENILLISGKHDLYVHSED
                     TDYLWESWERPTRYIYTCGHAGIVLKRKKIATDTINFIQNRLNSSHFPKDIP"
     gene            17446..18402
                     /locus_tag="EXW27_RS02205"
                     /old_locus_tag="EXW27_02235"
     CDS             17446..18402
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001982273.1"
                     /locus_tag="EXW27_RS02205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02235"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_002127565.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 4.1e-09, bitscore:
                     34.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTRVNPELLQGLEMFPNLDLHPENLQSIREGIAQMRPPTVVDES
                     LSLTDEVIVGPDDNPLPLRIYRPKSNNEPLPVLLWIHGGGYILGSIDDNDDTCMRFAKE
                     AGCVVVSVDYRLAPEHPYPAPIEDCYSALKWIADNAKSLNIDSNRIGVAGVSAGGGLTA
                     ALSLLARDRKYPSICLQMPLYPMIDDRNNTPSANEIKEGFVWNQKANEAGWKMYLGEMY
                     GTDQIPVYAAPSRAEDYSDLPYTYTFVGQLDPFRSETLTYVSKLAQAGVDVEFHLYPNA
                     YHWFEGLNPNADVSIYAVNEMVQAVKTGFKRVSKVEA"
     gene            complement(18491..19945)
                     /locus_tag="EXW27_RS02210"
                     /old_locus_tag="EXW27_02240"
     CDS             complement(18491..19945)
                     /NRPS_PKS="Domain: Beta_elim_lyase (137-335). E-value:
                     4.1e-11. Score: 34.6. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02210_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129520.1"
                     /locus_tag="EXW27_RS02210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02240"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_002127563.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.7e-06, bitscore:
                     23.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKNLQLSAEEMRQLGYQAVDLIVDHMNHLKSKPVSETIDSNIFR
                     DKLIETIPENGSNPKELLHFLNNNVFNQITHVDHPHFMAFVPGPNNYVGVIADFLASGF
                     NVFPTAWIVGAGAEQIELTTINWLKSMLGFPDSAEGLFVSGGSMANLTALTVARQVKLN
                     NDIENAVVYFSNQTHFSVDRALKVLGFKHHQICRIETDEDLRISVSTLRKQIKEDRLKG
                     KKPFCVIANAGTTNCGAVDSLDELADLCGDEDVWLHADGAYGAAAILSEKGREVLRGIH
                     RADSLTLDPHKWLFQPYDVGCVLIRNSQYLSKTFRMIPEYIKDTETNIEEKVNFGERGI
                     ELSRRFRALKVWLSFKAFGVTAFREAIDHGIMLAEQVEEFLRKEKDWEVVTPAQLGIVT
                     FRYIPCKRTSTETIHEINKKLVEEINQRGFAMLSTTKLKEKVVIRLCSINPRTTLEEIL
                     QIMMSIKALAEEINTSPKHLISVSQP"
     aSDomain        complement(18941..19534)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02210_Beta_elim_lyase.1"
                     /evalue="4.10E-11"
                     /label="EXW27_RS02210_Beta_elim_lyase.1"
                     /locus_tag="EXW27_RS02210"
                     /protein_end="335"
                     /protein_start="137"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AEGLFVSGGSMANLTALTVARQVKLNNDIENAVVYFSNQTHFSVD
                     RALKVLGFKHHQICRIETDEDLRISVSTLRKQIKEDRLKGKKPFCVIANAGTTNCGAVD
                     SLDELADLCGDEDVWLHADGAYGAAAILSEKGREVLRGIHRADSLTLDPHKWLFQPYDV
                     GCVLIRNSQYLSKTFRMIPEYIKDTETNIEEKVNF"
     gene            complement(20001..27011)
                     /locus_tag="EXW27_RS02215"
                     /old_locus_tag="EXW27_02245"
     CDS             complement(20001..27011)
                     /NRPS_PKS="Domain: AMP-binding (266-656). E-value:
                     1.4e-110. Score: 361.7. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02215_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (762-828). E-value: 1.4e-16. Score:
                     52.4. Matches aSDomain: nrpspksdomains_EXW27_RS02215_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (847-1144). E-value:
                     1.1e-88. Score: 289.4. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02215_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1303-1683). E-value: 2e-99.
                     Score: 324.9. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02215_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1789-1856). E-value: 6.9e-21.
                     Score: 66.2. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02215_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1903-2202). E-value:
                     3.2e-81. Score: 264.6. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02215_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547618.1"
                     /locus_tag="EXW27_RS02215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02245"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_003189455.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-112, bitscore:
                     373.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.3e-11, bitscore:
                     40.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-65, bitscore:
                     218.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIKDRSSIHENKGVEAFWKEQLSSEVLDFSVFNSGYQLNKENPY
                     EHVQVIMNVEFSKSIQKVIKSQDLLLFSWLQAALRICLAHYTDQERITIGIPVIEKNIE
                     QSENLNKLIPLGSEIYPHHSFKQVVNQIEQTTLFGYDNQSYPLSELLAKHHLTPFQIVI
                     GMEGLHNKNLIEEYAENNLAIWIQREWNEIHNEFEIQISFKSHSFSSLQQFANSYLYVL
                     KQVSTNSNLAVKDICIISEEEKELLEELNQGQADIELSQSFQNLFEEQVLKTPDQIAVV
                     CNDQSLTYRELNKKANQLASILQSKGVSKESIIGVMVDRSLEMIIGMVGILKAGAAYLP
                     IDPNYPNERIEYMLQDSQAKCLLSKRTEVELPQFAGEVLYLDEEYLFQGEESNLVRESY
                     PNDLAYVIYTSGSTGNPKGVMVEQKSLVHFLSVMREKVKDNQSFLFLASVSFDISLLEI
                     CLPLTQGSKVVIATEDQFATKELAYLVKEHKVDLWESTPSRMEVILSDPEGANFLKDLK
                     SILLAGEAFSIDLVEKIRCISEATILNIYGPTETTICATVKDLSSAKEVTIGSPNPNYH
                     SYILNKYGQLKPFGIPGELCIGGVAVARGYLGKSKLTDEKFVPSPFTAGEMMYHTGDLV
                     RWLPNGELEYLGRMDHQVKIRGYRIELREIESQLREYPEINQAIVVDQVYGNRKLLAAY
                     YVSDNKVSFDEIRKYLSDKLPEFMIPEKMIQVEEIPLNPNGKVDRKRLLDITQTDYVSI
                     PYVAPRNEIEQKLVHAWEKVMEIEGIGIHDNFFALKGESIKALQVINLLRKDCLKISTT
                     DFFKHPTIAQLSTCVKLEHKTENFENRPTHVKDLSKPFPLTEVQTAYMLGRNSQFELSG
                     ISPQTYFEYETELNINRLSKSFQKVIQRHPMLRAVILPEGEQQILQSVPDYEIEIVSLI
                     DLDDRNQNARLQEERSRMTNHVFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDGASM
                     NIVGQDLFHYYYKPEQRLEPLSFDFQDYMFIYDELEQSTEYKTAKDYWTSKLPDFPFAP
                     SLLLKKDPAEIATPKFQSLNKILDNEIWTKLRKLAQEKEVTPSALLCTIYSDVLAYWSN
                     QRRLAINLTVFNRYPVHEEVEQIVGDFTSLILLDVDVNPDQSFFTRVKETQSTLLDGLE
                     HRHYDGVNFIRDFTRYHQMTPKAVMPIVFTSMLAGAGAFAWEQLGSLRHIHARTPQVHL
                     DNVVIEKNGELLISWNYVEELFDVDVIEAMFHQFVDLLEQLVKQSDVTSLQMKELDHAL
                     IEQYNETTEKIPSTTLNQLFTDQVKRTPDEVAVVFEQDYLTYSELHKRSNQVAHFLKEQ
                     GIGLGDKVGLLAQRRVDTIVNMIGILKAGAAYVPIDPDHPSDRQTYILENSSCKLLLEP
                     SLYAENRLSLYTTEDMPAIAGPEDLAYIIYTSGSTGKPKGVIITHQAVANTIQDINQKY
                     QVNEDDRIIGISSMCFDLSVYDIFGTLSTGAMLVMIRDPRDMQELIRTVERRGITIWNT
                     VPAIMDLALDQVGSHFEHSSLRLVLHSGDWIPLSLPEKIKRHFPIAEVVSLGGATEASI
                     WSIYYPVKQVESHWKSIPYGIPLANQTYYVLNYEKKMCPVGVIGDLYIGGVGLAKGYLN
                     DEQKTNEAFVSHPDFGLIYKTGDCGKMHPEGYIEFLGRQDYQVKIQGYRVELEEIAHCL
                     LTYKQVEHAVVIDQTDEYGIKFLVAYVVTEKNISTTELRKHLRDHLPGYMIPSYFVYLE
                     QLPLTPNGKLDRKALPTPEKQTNEVFIAPKTEMEKILTSVWQEVLKVNRIGVNDHFFAL
                     GGDSIKAIQVSVRLYRQGFELEPKNLFSFPILGDMVQFVKKLDHLPNSQTSDVNKMNDN
                     KVTVLNVKDKQLNQHTLIKIQEKMPEIKIERIYPLAPFQEVIYEHAATEPDTNAYFEQT
                     IWALEGELDINLFIQCFQQLVDRHDSLRTIIVQDEQAQPWQAVLHDVQMISEIKNLIEM
                     TKQEQQEFLDQWMNENLSQGFKNDELMTRLCIFQLENNEHRVVWSSHHLLCDGWSVSIL
                     IDELFQLYETINAGTTAELPIVKPFETFIDWTVARDHEKARHFWRDYLSGYNRKISIPK
                     KKVPTQSEGLNFTFMDLTLDKDLTNQLQTFVTKNNITMNSALLAVWGILLGKYNGMREV
                     VLPNLVSVRPPEVEGIENMFGLFTNILPIRLAWTETQSFVDFLQKVQLETLKCNEYAYY
                     SFVDIQKQSELKTELTDHLWVFENYPTNSAIFSSNENRNFAITDYEVVDEPHVKYGIMC
                     FPEEKLTIKFGYDQTVYEAEKIQEILNHIHQLINMILQNPIQAIGDYKL"
     CDS_motif       complement(20250..20345)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0019"
                     /evalue="1.30E-10"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="2254"
                     /protein_start="2222"
                     /score="33.6"
                     /tool="antismash"
                     /translation="NEYAYYSFVDIQKQSELKTELTDHLWVFENYP"
     aSDomain        complement(20406..21302)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.20E-81"
                     /label="EXW27_RS02215_Condensation_DCL.1"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="2202"
                     /protein_start="1903"
                     /score="264.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLCDG"
                     /tool="antismash"
                     /translation="ERIYPLAPFQEVIYEHAATEPDTNAYFEQTIWALEGELDINLFIQ
                     CFQQLVDRHDSLRTIIVQDEQAQPWQAVLHDVQMISEIKNLIEMTKQEQQEFLDQWMNE
                     NLSQGFKNDELMTRLCIFQLENNEHRVVWSSHHLLCDGWSVSILIDELFQLYETINAGT
                     TAELPIVKPFETFIDWTVARDHEKARHFWRDYLSGYNRKISIPKKKVPTQSEGLNFTFM
                     DLTLDKDLTNQLQTFVTKNNITMNSALLAVWGILLGKYNGMREVVLPNLVSVRPPEVEG
                     IENMFGLFTNILPIRLAW"
     CDS_motif       complement(20415..20489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0018"
                     /evalue="5.90E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="2199"
                     /protein_start="2174"
                     /score="28.4"
                     /tool="antismash"
                     /translation="VSVRPPEVEGIENMFGLFTNILPIR"
     CDS_motif       complement(20541..20579)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0017"
                     /evalue="1.20E+01"
                     /label="Cy4"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="2157"
                     /protein_start="2144"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="NITMNSALLAVWG"
     CDS_motif       complement(20835..20897)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0016"
                     /evalue="1.30E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="2059"
                     /protein_start="2038"
                     /score="33.7"
                     /tool="antismash"
                     /translation="HHLLCDGWSVSILIDELFQLY"
     CDS_motif       complement(21114..21230)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0015"
                     /evalue="4.80E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1966"
                     /protein_start="1927"
                     /score="47.8"
                     /tool="antismash"
                     /translation="AYFEQTIWALEGELDINLFIQCFQQLVDRHDSLRTIIVQ"
     aSDomain        complement(21444..21644)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_PCP.2"
                     /evalue="6.90E-21"
                     /label="EXW27_RS02215_PCP.2"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1856"
                     /protein_start="1789"
                     /score="66.2"
                     /tool="antismash"
                     /translation="EKILTSVWQEVLKVNRIGVNDHFFALGGDSIKAIQVSVRLYRQGF
                     ELEPKNLFSFPILGDMVQFVKK"
     aSModule        complement(21444..24470)
                     /complete
                     /domains="nrpspksdomains_EXW27_RS02215_Heterocyclization.1"
                     /domains="nrpspksdomains_EXW27_RS02215_AMP-binding.2"
                     /domains="nrpspksdomains_EXW27_RS02215_PCP.2"
                     /locus_tags="EXW27_RS02215"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(21933..21995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0014"
                     /evalue="2.70E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1693"
                     /protein_start="1672"
                     /score="26.1"
                     /tool="antismash"
                     /translation="FLGRQDYQVKIQGYRVELEEI"
     aSDomain        complement(21963..23102)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_AMP-binding.2"
                     /evalue="2.00E-99"
                     /label="EXW27_RS02215_AMP-binding.2"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1683"
                     /protein_start="1303"
                     /score="324.9"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FTDQVKRTPDEVAVVFEQDYLTYSELHKRSNQVAHFLKEQGIGLG
                     DKVGLLAQRRVDTIVNMIGILKAGAAYVPIDPDHPSDRQTYILENSSCKLLLEPSLYAE
                     NRLSLYTTEDMPAIAGPEDLAYIIYTSGSTGKPKGVIITHQAVANTIQDINQKYQVNED
                     DRIIGISSMCFDLSVYDIFGTLSTGAMLVMIRDPRDMQELIRTVERRGITIWNTVPAIM
                     DLALDQVGSHFEHSSLRLVLHSGDWIPLSLPEKIKRHFPIAEVVSLGGATEASIWSIYY
                     PVKQVESHWKSIPYGIPLANQTYYVLNYEKKMCPVGVIGDLYIGGVGLAKGYLNDEQKT
                     NEAFVSHPDFGLIYKTGDCGKMHPEGYIEFLGRQDYQVKI"
     CDS_motif       complement(22071..22160)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0013"
                     /evalue="8.90E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1647"
                     /protein_start="1617"
                     /score="43.6"
                     /tool="antismash"
                     /translation="PVGVIGDLYIGGVGLAKGYLNDEQKTNEAF"
     CDS_motif       complement(22671..22730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0012"
                     /evalue="2.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1447"
                     /protein_start="1427"
                     /score="32.0"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVIITH"
     CDS_motif       complement(22875..22913)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0011"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1379"
                     /protein_start="1366"
                     /score="17.7"
                     /tool="antismash"
                     /translation="GILKAGAAYVPID"
     CDS_motif       complement(23478..23519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0010"
                     /evalue="1.30E-03"
                     /label="afterCy5"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1178"
                     /protein_start="1164"
                     /score="11.8"
                     /tool="antismash"
                     /translation="LEHRHYDGVNFIRD"
     aSDomain        complement(23580..24470)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_Heterocyclization.
                     1"
                     /evalue="1.10E-88"
                     /label="EXW27_RS02215_Heterocyclization.1"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1144"
                     /protein_start="847"
                     /score="289.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DALLMDG"
                     /tool="antismash"
                     /translation="KPFPLTEVQTAYMLGRNSQFELSGISPQTYFEYETELNINRLSKS
                     FQKVIQRHPMLRAVILPEGEQQILQSVPDYEIEIVSLIDLDDRNQNARLQEERSRMTNH
                     VFPLGQWPLFELKAFLLKEDTYLLCFRYDALLMDGASMNIVGQDLFHYYYKPEQRLEPL
                     SFDFQDYMFIYDELEQSTEYKTAKDYWTSKLPDFPFAPSLLLKKDPAEIATPKFQSLNK
                     ILDNEIWTKLRKLAQEKEVTPSALLCTIYSDVLAYWSNQRRLAINLTVFNRYPVHEEVE
                     QIVGDFTSLILLDVDV"
     CDS_motif       complement(23583..23642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0009"
                     /evalue="5.00E-09"
                     /label="Cy5"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1143"
                     /protein_start="1123"
                     /score="28.2"
                     /tool="antismash"
                     /translation="HEEVEQIVGDFTSLILLDVD"
     CDS_motif       complement(23643..23678)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0008"
                     /evalue="3.40E-03"
                     /label="afterCy4"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1123"
                     /protein_start="1111"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AINLTVFNRYPV"
     CDS_motif       complement(23694..23750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0007"
                     /evalue="8.40E-09"
                     /label="Cy4"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1106"
                     /protein_start="1087"
                     /score="28.1"
                     /tool="antismash"
                     /translation="VTPSALLCTIYSDVLAYWS"
     CDS_motif       complement(24012..24068)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0006"
                     /evalue="2.50E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="1000"
                     /protein_start="981"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LLMDGASMNIVGQDLFHYY"
     CDS_motif       complement(24273..24326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0005"
                     /evalue="7.50E-09"
                     /label="Cy2"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="913"
                     /protein_start="895"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VIQRHPMLRAVILPEGEQ"
     aSDomain        complement(24528..24725)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_PCP.1"
                     /evalue="1.40E-16"
                     /label="EXW27_RS02215_PCP.1"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="828"
                     /protein_start="762"
                     /score="52.4"
                     /tool="antismash"
                     /translation="EQKLVHAWEKVMEIEGIGIHDNFFALKGESIKALQVINLLRKDCL
                     KISTTDFFKHPTIAQLSTCVK"
     aSModule        complement(24528..26213)
                     /complete
                     /domains="nrpspksdomains_EXW27_RS02215_AMP-binding.1"
                     /domains="nrpspksdomains_EXW27_RS02215_PCP.1"
                     /locus_tags="EXW27_RS02215"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(25014..25079)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0004"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="666"
                     /protein_start="644"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YLGRMDHQVKIRGYRIELREIE"
     aSDomain        complement(25044..26213)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02215_AMP-binding.1"
                     /evalue="1.40E-110"
                     /label="EXW27_RS02215_AMP-binding.1"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="656"
                     /protein_start="266"
                     /score="361.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVLKTPDQIAVVCNDQSLTYRELNKKANQLASILQSKGVSKE
                     SIIGVMVDRSLEMIIGMVGILKAGAAYLPIDPNYPNERIEYMLQDSQAKCLLSKRTEVE
                     LPQFAGEVLYLDEEYLFQGEESNLVRESYPNDLAYVIYTSGSTGNPKGVMVEQKSLVHF
                     LSVMREKVKDNQSFLFLASVSFDISLLEICLPLTQGSKVVIATEDQFATKELAYLVKEH
                     KVDLWESTPSRMEVILSDPEGANFLKDLKSILLAGEAFSIDLVEKIRCISEATILNIYG
                     PTETTICATVKDLSSAKEVTIGSPNPNYHSYILNKYGQLKPFGIPGELCIGGVAVARGY
                     LGKSKLTDEKFVPSPFTAGEMMYHTGDLVRWLPNGELEYLGRMDHQVKIR"
     CDS_motif       complement(25161..25250)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0003"
                     /evalue="1.60E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="617"
                     /protein_start="587"
                     /score="39.6"
                     /tool="antismash"
                     /translation="PFGIPGELCIGGVAVARGYLGKSKLTDEKF"
     CDS_motif       complement(25746..25802)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0002"
                     /evalue="3.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="422"
                     /protein_start="403"
                     /score="31.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMVE"
     CDS_motif       complement(25986..26024)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW27_RS02215_0001"
                     /evalue="7.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="EXW27_RS02215"
                     /protein_end="342"
                     /protein_start="329"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GILKAGAAYLPID"
     gene            complement(27044..28021)
                     /locus_tag="EXW27_RS02220"
                     /old_locus_tag="EXW27_02250"
     CDS             complement(27044..28021)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290962.1"
                     /locus_tag="EXW27_RS02220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02250"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_016101928.1"
                     /sec_met_domain="PF00881 (E-value: 3.5e-23, bitscore: 80.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQIYYWSPIKHWEKLHNEILIGETRFTGVLSEWFPEFYFFTQK
                     GVKISELVEHFSLGNVEETQKTVELMIKNRVLVSNILHPREVFSTQEKIFPNPYSNQIR
                     FSKEDLDKYMSEQLNRTHHAVRSTEIQLETTNELPTIIKERRSCRQFDMKKHISFLEFS
                     QFISTLKQVRKEHIYYHYASAGGLYPIDIFIYIKPKRIEGMKAGFYYYNPAKNCLVIVN
                     NIDQVIKSDHELINQDLFTQSAFSVYLVYNANASIPKYGSDGYLFACIESGIITATLNM
                     VAETLNLGVCSVGHMKFEEIQQFLCLDNHQVFLHGLEVGLKINE"
     misc_feature    28753..28769
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: medium, score: 28.23"
                     /tool="antismash"
     gene            complement(28892..31462)
                     /gene="pulA"
                     /locus_tag="EXW27_RS02225"
                     /old_locus_tag="EXW27_02255"
     CDS             complement(28892..31462)
                     /EC_number="3.2.1.41"
                     /GO_function="GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pulA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167496.1"
                     /locus_tag="EXW27_RS02225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02255"
                     /product="type I pullulanase"
                     /protein_id="WP_147740468.1"
                     /sec_met_domain="CBM_48 (E-value: 2.1e-13, bitscore: 48.7,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 2.2e-20, bitscore:
                     71.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQITKKLINKSFLLLTIIVMLSSVFSFQSVKAVSNSKTTEVIIHY
                     KEKSGNTKDWNLWVWGENANGKSYEFTGEDEFGKYAKIKIGGDYNRVGFIVRTNEWEKD
                     GGDHWVENIRDGRAEVWILSGDEKVYDSKPSSDLSIQKATIDSFNEITVTTNVPFNSKE
                     QKIEIEGVKIKGISPYDKNSGDITNKVKIITEQKIDLKQTYKVKIANLADANTEIGKVI
                     RSEEFDNLFYYGGNDLGNIYTPQHTKFRLWAPTASEAKLVTYKKWSDKIGTEINMKQGE
                     KGTWKAELKGNQKGLFYTYKVKIGDKWTEAVDPYVRAASVNGDKGAVVDLEETNPKKWK
                     ANKKPKFKNPEDAIIYELHVRDLSIQPESGIKQKGKYLGVTEKGTKGPEGVKTGLDHMK
                     DLGVTHVQFLPIFDYASVNEENLNEPQYNWGYDPENFNVPEGSYSTNPFEPTVRITELK
                     QMIQTLHDNNLRVVMDVVYNHMYNAAESNFHKLVPGYYYRYNEDGTLANGTGVGNDTAS
                     ERKMMRKFMVDSVTYWAKEYNLDGFRFDLMGIHDYETMNEIRKAVNQIDPSIILHGEGW
                     DLNTPLAAELKANQKNAEKMKGIAHFNDNIRDGLKGSVFEEKENGFVNGKQNMEDRIKK
                     GITAGIDYDTNSSTYQDPEQVLTYVEAHDNHTLWDKLELTNSGDSEEMRKQMHKLSSSI
                     LLTSQGIPFLHAGQEFMRTKYGDHNSYKSPDSINQMDWLRRAAFNNEVEYMKGLIDLRK
                     KYPAFRMTSAEQIKKYVAFIDVPKNVVAYTIDGKGSGNKSEYFMVAHNANREAVDITLP
                     SKGPWKVLVNENQAGSKTLYVVHDNKIKVPALSSLVLKTEKPNK"
     misc_feature    complement(31637..31648)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.81"
                     /tool="antismash"
     gene            complement(31978..33681)
                     /locus_tag="EXW27_RS02230"
                     /old_locus_tag="EXW27_02260"
     CDS             complement(31978..33681)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791466.1"
                     /locus_tag="EXW27_RS02230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02260"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_016127039.1"
                     /transl_table=11
                     /translation="MKNTKTLTKVALTTGLALTAVAPYGIGHAEETDQLQVQIQEDSFR
                     SGELTQPSQKTPENVVKDALKEKAEQALSPNQVNGETGVDYKVLQKRGSYDGTTLVRMQ
                     QTYEGKEVYGHQLTAHVDNNGVIKSVSGDSAQNLKQEELKKPINLSKDEAKQYIYTKYG
                     NDIKFISEPEVKEVIFVDENNGQASNAYQVTFEAATPNYVSGTYLVNAQNGDMLKNMVQ
                     ESNLKASEKLVGALKESKKSSLTSLTGTGKDDLGISRSFGISKQSNGKYALADYTRGQG
                     IETYDVNYRDITKEESYYPGTLATSTSTTFNDPKAVSAHYLATKVFDFYKDKYKRNSFD
                     NKGQKVVSVVHAWDSEDTNDPKNWQNALSANNGSMLVYGDPIVKAYDVAGHEFTHAVTS
                     SESNLEYYGEPGAINEALSDIMGTSIEKYVNNGSFNWTMGEQTGSVFRDMENPASVPSS
                     LGVPYPDDYSEFNDFNGWDQGGVHFNSSIINKVAYLIAKGGTHNGVTVKGIGEDKMFDI
                     FYYANTDELNMTSNFKELKSACIRVATNKYGANTAEVQAVQKAFDAAKIK"
     gene            complement(34368..36314)
                     /locus_tag="EXW27_RS02235"
                     /old_locus_tag="EXW27_02265"
     CDS             complement(34368..36314)
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129515.1"
                     /locus_tag="EXW27_RS02235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02265"
                     /product="bifunctional UDP-sugar hydrolase/5'-nucleotidase"
                     /protein_id="WP_002032306.1"
                     /transl_table=11
                     /translation="MQKMKWKNYVCNFIILMLLVTAVTVKPAISKAEESNVNITLLGTA
                     DIHGRFMPWDYALDGANMSGSLTQLYTVIKKVRQENPNTILVDAGDTIQGNSVELFNDK
                     PQSPMMVAMNTMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAY
                     TIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEDKVDVMVGV
                     MHMGLENENGIPGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHIS
                     RIDLTFTKQDGKLVLKDKTATAIPVKNADGTTVLSDSTLEETLTPFHEYARGDANVVVA
                     QLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLHYSKADVVAHQIDNDYARLDIGPI
                     KKKDIAYNYQYALGEITVYKITGKDLKDYMEWAAGYFNSSRAGDVTVSFDKNRRASKYS
                     TNDFFGGVKYEIDLTKPYGSRITNLRSIRTNKPIKMSDVMTLGMNAYRMEALQAKGGAL
                     EGRKFEQTWSSKQENAFGETGGTIRNLAITYLKEVKNGVYTPKVMHNWKITGVDTHSSE
                     HKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVALSQKANINPNQFNHVKR
                     KGEFYKKLSRIIK"
     misc_feature    36694..36709
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.01"
                     /tool="antismash"
     misc_feature    36707..36720
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.59"
                     /tool="antismash"
     gene            complement(36871..37386)
                     /locus_tag="EXW27_RS02240"
                     /old_locus_tag="EXW27_02270"
     CDS             complement(36871..37386)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379366.1"
                     /locus_tag="EXW27_RS02240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02270"
                     /product="DinB family protein"
                     /protein_id="WP_078179238.1"
                     /transl_table=11
                     /translation="MNTFVNDTFYETRNQLFEEITLLSDAQFNRKPDKDKWSIAKVCHH
                     LVLLDERVITVISSGLKKMDSILNERKEIHTILLDRSIKFIAPEMIEPSIEPFEVQQMV
                     DLLNDSRKELMRFLSTIEDESILAKKSVTHPALGELLLDQWIELIYLHEQRHIEQIKEI
                     KLLCGVEK"
     gene            37923..39227
                     /gene="secY"
                     /locus_tag="EXW27_RS02245"
                     /old_locus_tag="EXW27_02275"
     CDS             37923..39227
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0015031 - protein transport [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016091122.1"
                     /locus_tag="EXW27_RS02245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02275"
                     /product="preprotein translocase subunit SecY"
                     /protein_id="WP_002069884.1"
                     /transl_table=11
                     /translation="MFRTISNFMRVAEIRNKILFTLAMLIVFRIGTFIPVPHTNAEVLK
                     VQDQANVLGMLNVFGGGALQHFSIFAVGITPYITASIIVQLLQMDVVPKFTEWAKQGEM
                     GRKKSAQFTRYFTIILAFIQSIGMSYGFNNIAGGQLITDQSWTTYLFIATVLTAGTAFL
                     LWLGEQITANGVGNGISMIIFAGLVAAIPNVANQIYLQQFQNAGDQLFMHIIKMVLIGL
                     VILAIVVGVIYIQQAVRKIPIQYAKAVSGNNQYQGAKNTHLPLKVNSAGVIPVIFASAF
                     LMTPRTIAQLFPDSSVSKWIIANLDFAHPFGMTLYVGLIVAFTYFYAFIQVNPEQMAEN
                     LKKQNGYVPGIRPGKSTEQYVTKILYRLTFIGAIFLGAISILPLVFTKIATLPPSAQIG
                     GTSLLIIVGVALETMKTLESQLVKRHYKGFIKKVN"
     gene            complement(39326..39556)
                     /locus_tag="EXW27_RS02250"
                     /old_locus_tag="EXW27_02280"
     CDS             complement(39326..39556)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EXW27_RS02250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EXW27_02280"
                     /product="hypothetical protein"
                     /protein_id="WP_016101932.1"
                     /transl_table=11
                     /translation="MVGIPIYQRIDLFLGEIDYLEAKVFGIKGDKRIVRKQVITLKDFV
                     PDYLIIDKFMLRLFITTEGYIEGERKELLLW"
     gene            complement(39719..40384)
                     /locus_tag="EXW27_RS02255"
                     /old_locus_tag="EXW27_02285"
     CDS             complement(39719..40384)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391640.1"
                     /locus_tag="EXW27_RS02255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02285"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_078179050.1"
                     /transl_table=11
                     /translation="MEEQTNTITSRRSRPAKEPLSKEIIVKTAYDLLESEGISGLSMRK
                     IAKVLDTGPSSLYVYVKNADELRAYVLDYGLGKIEITDEKNEPWKKELFTLVYSYFRIL
                     FDSSGMAELALMTIPIGPNSLALTEQILCQLHEGGVNARASAWGVDILLLYAASVAYEQ
                     TARKEKGTTLDPIRASYEALDTARYPMIVSLKENMLSGGEERFRWGLEVVLQGILHTQ"
     gene            complement(40409..41572)
                     /locus_tag="EXW27_RS02260"
                     /old_locus_tag="EXW27_02290"
     CDS             complement(40409..41572)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003189438.1"
                     /locus_tag="EXW27_RS02260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02290"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_078179049.1"
                     /transl_table=11
                     /translation="MMERKNKGEKRIAIIGAGPGGLTLARILQKHGLKCVVYERETSPW
                     IRQQGGSLDIHHDSGQEALKEAGLLEQFNELARYEGEDFRLCDKNGKIYLDEVADPNCG
                     DRPEIDRGTLRELLLNSVDPQCIHWGYNLTKAIPVENGIHELHFENGHVDTVDLVVAAD
                     GAFSRIRPLVTNSIPQYTGISMVELNLKNVTKNHPQMAKFNRRGKVFALAEHKGILAQL
                     NGDDSIRVYLSFRTDKKWLDNCGIPFKNLEEAKHQLLQYFEDWDETLKNYIRCADGAIF
                     PRRIYMLPVGLTWKSNPGVTLIGDAAHLMSPFAGEGVNLAMRDAAELALSIVKHDNLNE
                     AIENYEEKMYDYSSQSAEVSNDNLEICFSEDATMKMYNLMNQLHEQQ"
     gene            complement(41790..42707)
                     /locus_tag="EXW27_RS02265"
                     /old_locus_tag="EXW27_02295"
     CDS             complement(41790..42707)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234336.1"
                     /locus_tag="EXW27_RS02265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02295"
                     /product="DMT family transporter"
                     /protein_id="WP_016101934.1"
                     /transl_table=11
                     /translation="MVILNYILVCIIFGTTFLTIKIGIEAGAPPLFSAGIRFFLAGLIL
                     IIIFKLKRKDIMPYLLSKRIIYAGFCLTFMTFATLYWAEQYISSGLAAVLSATAPMMIL
                     LLQSRRNKTKLQKEQLVALVIALTGVLFISLPGMHQELTFIWSIACLVILVGELFYGIG
                     SIRSKEILSDLPNVSPFLINGIQMFYGGVLLLIVSVVMEQPNLAVLTSWNVQWPILYLI
                     FVGSIGGHGLYYWLLSKTNPVFPSTWLYVSPLIAVIVGYFVLGEPLNPAMGIGACLILI
                     GVFLANRSTLGVYFKQGKLLKKEM"
     gene            42856..44295
                     /locus_tag="EXW27_RS02270"
                     /old_locus_tag="EXW27_02300"
     CDS             42856..44295
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (139-468). E-value:
                     2.9e-35. Score: 114.0. Matches aSDomain:
                     nrpspksdomains_EXW27_RS02270_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698370.1"
                     /locus_tag="EXW27_RS02270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02300"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_016127035.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.8e-33, bitscore:
                     113.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVLRKESNIPYYQQIYMQIVERIQSGMLSHGDYLPSLRSMADD
                     LQISLLTVRKAYKQLETKSYIRIEQGKGAYIHKRVNKDFKPIPYQWQQTKSINVMRSQY
                     VMNQHRKYFDFSQAVLYPRLLPNPFLSDEMHKLLNKDQMILATYGPVQGDKELRVEITN
                     YLKEHQQVVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYGAALDVFVNKGVQ
                     IIPVSLDNNGIRSDLIDDICQRKNPVLLYVNPTFQNPTGTVMSKERRMELVELAELYQF
                     FILEDDSFGEIYFEDFKIPPPIKSFDTNGHVIYLKGFSKTLAPGLRIAALAAEGPIFEW
                     LYAVKASMDIGSPLLTQKALLPFLRAERMKNHLEKLRTALQIRRDLTIDILSPLKELEF
                     EIPNGGFNLWVTLPQSIDPFTLLQKANEVDVSFLPGTACLINHETQYNHLRISYSMLNE
                     KDMLIGLERLHDTIAKFKSMI"
     aSDomain        43273..44259
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW27_RS02270_Aminotran_1_2.1"
                     /evalue="2.90E-35"
                     /label="EXW27_RS02270_Aminotran_1_2.1"
                     /locus_tag="EXW27_RS02270"
                     /protein_end="468"
                     /protein_start="139"
                     /score="114.0"
                     /tool="antismash"
                     /translation="KDQMILATYGPVQGDKELRVEITNYLKEHQQVVTDPSQLLITSGA
                     QQGIDLIAQTLLKPGDIVLVESPCYGAALDVFVNKGVQIIPVSLDNNGIRSDLIDDICQ
                     RKNPVLLYVNPTFQNPTGTVMSKERRMELVELAELYQFFILEDDSFGEIYFEDFKIPPP
                     IKSFDTNGHVIYLKGFSKTLAPGLRIAALAAEGPIFEWLYAVKASMDIGSPLLTQKALL
                     PFLRAERMKNHLEKLRTALQIRRDLTIDILSPLKELEFEIPNGGFNLWVTLPQSIDPFT
                     LLQKANEVDVSFLPGTACLINHETQYNHLRISYSMLNEKDMLIGLERL"
     gene            complement(44636..45058)
                     /locus_tag="EXW27_RS02275"
                     /old_locus_tag="EXW27_02305"
     CDS             complement(44636..45058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771488.1"
                     /locus_tag="EXW27_RS02275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02305"
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_002136501.1"
                     /transl_table=11
                     /translation="MKLLLIVVAVGLLWFISFLHIYWAFGGRWGSAAVIPVKEGEHKPA
                     FTPRIWGTLFVAILILLASVIIVVQVGYLQGFEANSLSKIGSIVCALVFIVRAIGDFKF
                     VGFFKKIKHSQFARYDTWFYSPLCLFFGFVYIMLLF"
     gene            complement(45217..45750)
                     /locus_tag="EXW27_RS02280"
                     /old_locus_tag="EXW27_02310"
     CDS             complement(45217..45750)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001177627.1"
                     /locus_tag="EXW27_RS02280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02310"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_002013313.1"
                     /transl_table=11
                     /translation="MQLTREDWIKVGLQQLANEGIHKVRIEALARLLKISKGSFYHYFR
                     DHQELLDSMLDFWEVHATKLIVQSMEQQDASLEQLLQISFNRDKKIENGIYAWAKYDPV
                     VATRLVDIEEQRISCVAKLYQKMGVDETESIDRARLAYLTYVGWMTRFEANLNFDIDKM
                     VELLTSFSGCPNIH"
     gene            complement(45979..46476)
                     /locus_tag="EXW27_RS02285"
                     /old_locus_tag="EXW27_02315"
     CDS             complement(45979..46476)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022985.1"
                     /locus_tag="EXW27_RS02285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02315"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_002085380.1"
                     /transl_table=11
                     /translation="MNILFESIILILTGIIVLKLTGSKSVSQMTRAEIIIVVSIGRIIV
                     EPILSRKVGPSIFAAFIFAGVLLIIHFFELKSRKVEKFLNGNSIIVIENGEILKKNLLR
                     AKMSEQQLFMHLREKGIHEIKNLQQATVETNGRIGYQLTTKAQPVTLEMLEKLLEQCNL
                     KK"
     gene            complement(46460..46732)
                     /locus_tag="EXW27_RS02290"
                     /old_locus_tag="EXW27_02320"
                     /pseudo=""
     CDS             complement(46460..46732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189695.1"
                     /locus_tag="EXW27_RS02290"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW27_02320"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEIFVAGATARSLIPMLIKEGHTVYAMIRNESQVEAMKKVDALPL
                     LAGREVLQRIRHVK"
ORIGIN
        1 tcatacatat gaagaagctg aggaaacgtt aaaaacgtta actataccgc agtttccgaa
       61 acatattaga cgaaaaccat ttaaaccaaa aataataaaa atagccgatt ctgaataaga
      121 accggctatt tttatattca caactcaata gcaaataaag tatataaaag ctctttatat
      181 tgattttctg taatttcacg cttcgttttt tctccataaa taatttcagt taaaatagta
      241 ttcgttaatg agacatggcc aaagttcgtc aattttactg caatgggtcc tttattgaaa
      301 atagatttct catcttctat cactcttctt tgaacatcgt ttactactgt ctcatcaata
      361 atatgtttat aaaaagcatg acaaactttc cattctccat caacatctat tctttctaga
      421 acatagtttc ctttactcgt atctttttgt cttactcgat acgaaccgtt tttagaagaa
      481 acaagttcgc cagtaaacgg tactggcaca agaggtacta atgaagcaat acctacatca
      541 attaagtacc ttacgttttc gtaatttaaa ataattgtta tatgcccatc ttcaagtgcc
      601 caagcgttta tatcattttt atatacggta cctagtgcga gttgtacatc ataaccacta
      661 tcttttaaaa aatagtaaaa aagagtattt aattcataac aaagcccacc tcgagaacta
      721 gttaaaattt tctcttgtaa gtttttcata gaaattgtat tcgcattact tgctattaca
      781 tttaaattct caaacgggat tgtgtgggca aatacaaaga gtattgtact taattcttca
      841 aattttattt cagtacgttt ttcaaggttt aatcttgtga aaagttgatc ttgtaacttt
      901 gtcatattca gcacccctta ataagttata aattaaaata atatatgctg attgtaaatt
      961 tgaagggata tagtaacaat gtacatttgc agttactgta ccggtacaaa atttaaattt
     1021 gaaaaacata tttatataaa aatacaaata agaggcacct tcacggatgc ctctttcgaa
     1081 ttacatttta tatctttatt tcaatgagct taatttttca attgcttgtt gctcagttgc
     1141 taagaaaaaa atatccttac ctttattaca ttcataaatg aaatctttta ggcttttact
     1201 agtgtacata gaaaaatccc cgatgatagc aattttcacg ctgtaattaa taaacttttg
     1261 aagaatatca cccgcaagac gtgtttttaa gtcaaagaaa ctttcactta ttaatgattt
     1321 attgatagca atccgctttg aatccgcttc atattgaact gttgccatga gatctaatgc
     1381 agattgaacg tcggatatta atactgtatc gtttctgacg acggcaatat ttattccgcc
     1441 aattactact ttctttattt ccatagtctc acccctctat aatttataaa gtatatatta
     1501 aacatgctgt gtagatcttc attaacacac ataaatgatt tgcccctggc tcgataacct
     1561 ctatttcatc gtaaataaat attgttttaa aacttctcat acggtcaatg aaattaaggg
     1621 taatctatct ttttactatt tttggaaatt tatctctcca caataactta ataaattatc
     1681 aaaagaagta atctcggcat atggtttagt atcggtatta ttcttaatca tattaggatt
     1741 gaaccatatg ccctttatat ttgcattttg acaaccagca atatcctttt ctaagtcatc
     1801 tccaacaaat agtacatctt ctgattgtac atttagctta tttaatgcta attcaaatat
     1861 gagtttgtca ggtttactaa atcccgcttc ttcaaaaata atgattgtat caaaataacg
     1921 attcaaattc gtgttaatta ttttttcttt ttgcctctga gttgagccat ttgttataat
     1981 tccaacttta atatgtgact ttatagtatt tatgatatta atagtttttt ggtttataga
     2041 aaaacatttc gggaaattat tattccaaaa gtcttgaatg taattgcgtg gtaatctata
     2101 tttcggtggg aattcatcaa aaaacgattc caaaaccttt actttatcac tatgaccata
     2161 gcttttttta tcatatccct tgaatttctg taacatttcg ttttttactg catgttgttc
     2221 aacatcccca taaaactcct ctaaaataat ggaaaacagt ttatctactg ccttatccct
     2281 atcaagtaac gtatcatcta aatcaaatag catagcttta taactcctca aataatttca
     2341 caacctttct cacatgattt aaataatccc ttgttcgcac cttaggcctt tactaaatta
     2401 gcaaaaaaac tacaaagttt gtggcgtacg ctctagaatt tcgctggcct cttttatatt
     2461 taaattcatc tccctttccc cttctagtaa agtatcgaaa gtatattatc aaacagttaa
     2521 aaaaaactac atacaattta cattattata cattattttt ttgtaaatat taatcgttca
     2581 gctttttata tgataagttt tttcaagcac acaaatattt ctccataaaa aaggaatatg
     2641 ggtaataatc cttttttacg gagaatacac aatcttgaaa agggagttaa tacgttaaac
     2701 gtcctatgaa gtttcctact gtatctccac ataaactcca gatagtaagg ctataatgac
     2761 taccagaggt gatattatga aaaactatca tattctcgtg gtagaagacg atcaagaaat
     2821 tcaggaatta attaaacaat ttttaatgac acaacagtat acagttgtag ttgcatcaga
     2881 tggattagag ggtatgacac aatttaataa gcaatccttt gatttaattc ttctagatgt
     2941 aatgatgccc aatcttaatg gatttgaagt atccaagatg attcgaagtc agtcaaacgt
     3001 accaattatt atgctaactg cattggaaga agaggaagat caaatgaaag ggttcgatct
     3061 tggaatcgat gattatataa caaaaccctt ttcgtttcat gttttgatta gacgagtcga
     3121 agctgtactt agaagaagtt atgataaaaa tgtaaataat catttggtat ttaaagaagt
     3181 gcgtatcgat gttgatgcat atagagtata tgtaaatgac gttgaaattt tattaacgac
     3241 aaaagagttt gaaattctac aactactatt tcaaaatgag agaaaagtac tcacaagaga
     3301 aaatatcgta gaaaaagttt gggggtacga ttattttgga gaaacacgaa taattgatac
     3361 acatattaaa aacctacgta aaaagttagc tatcccttat attaaaacaa taaagggtat
     3421 tggttataaa attgatgaat agtattgtga aaatcatgaa gatgaagcaa attacttata
     3481 aactctttat gactacctct ctcattttgt tatcctttgc agtattgatt tatttaactt
     3541 tatacttctt tctccctacg ttttatgagc aatacaaaac agatcaactt caaacaggga
     3601 taaaagaaat cattgataaa tctaaagatc ttacgtttca agatgcgata ccactttttg
     3661 atgaatatgc aaaaaaaaat aatgcgatgc tttatcttca aaataatgag ggaataatta
     3721 aatactctcc ttcattttct tttactcaaa atggttcgca aacaacagta gttactagag
     3781 ccacacggtt cgagaatgca ggtaccctta gtaattcata taacgttacg aaaccaattc
     3841 aattccaaga tggtagttta acgcttatag tctttgctac atttcaacca attgatgaag
     3901 cttcacaggt tttagtacgc tttctcccct atattagtat cattgtactc ataattggtg
     3961 tagggagtgc ttatttctat tccaggttta ttacaaaacc acttatttat attaatgagg
     4021 gtgcacaaaa gatggcaaat ttagatttct ccgaaaaaat tgaggttcgc tctacagatg
     4081 agttaggaga attatctaat agtttgaatg acatgtctat taacttacaa caagctatgt
     4141 ttgatttaaa aaaagcaaat caacaattaa aaaatgatat tgaaaaagaa cgagaaatag
     4201 aaacaaaacg cagagagttt tttgcgattg tagcacatga attaaagacc cctcttactg
     4261 taatgaaagg atacttagaa gggatgatat acaatattgg cccttatcaa aatcgtgatc
     4321 aatatttaaa gaaaaatcat caaattattg aaagtatgga acaattagtt cgtgaaattt
     4381 taagcatgtc gaaattagaa caacacacct ttaaactaaa agtagaagaa gttaatcttt
     4441 cgaagttaat agatacaatc acaaaagatc tcgaattttt tgcttctcaa aaaagcatcc
     4501 aaataataaa agaaattgat tctgatcttt ctgtttatac agatcgtgtt ctttttgaaa
     4561 aagcatgtaa aaatattatc cataatgcgg ttatgtattc accacataat gaaaaagtct
     4621 atataaagtt aagtgaggat tctaaacaag gtcaaatcaa aatgcaaatt atgaatacag
     4681 gtgtcaatat taaagaagag gatatacaac aaattttcaa accattttat cgaattgaaa
     4741 aatcaaggaa tcgaaatact ggaggaagtg gtttggggct atatattgtt aaacaaattc
     4801 ttgaaacgtt agatataaag tattctataa agaatatgga acgtagtgta caatttagca
     4861 tgaacattcc attatctaaa caaaaaacaa acaaactccc ctcttagtag gacgagtttg
     4921 tttgtttttt gtaattttag tattgatatt tttcgagtta ctttttaagc aatattggga
     4981 ttagcttttt taccaatcca catacctaag cccaccatgc caagccaaca gcaaattgct
     5041 aacataaaca tcaatcgttg tacggataac ccttcaatct gcatttgacc cttcccaaca
     5101 attgtttgga aaagttgcga ccattcgaca tcgtaaaaca cccctactcc cacaatcaca
     5161 atcaatgtaa aaaattgtaa aaatatattc cccatatttc tccatgttgt gtaaatgagt
     5221 aaagaaagct ctctatgtgt agcattcacc atatatactt tcatattatt ttgagaagaa
     5281 atactattaa tggcatagct tccaaatgta acgctaagga ctataaatat tggagaataa
     5341 aacccgaata tcatgattaa agtacttact aaaaacaaat ggattggatt aactttctta
     5401 gcagctttga tatctaaaaa tatggacatc aaaatcccta ataggtatgg tccaactaca
     5461 atgaaaatac aggttaacat gttatagaaa gtaaaactat aaaaaatacc catcaaaaat
     5521 aaatatccat ttcctaatcc aagtaaaaat gattctgcct ttaagcggat tggtaaagaa
     5581 gatgaaagtt tatgaaagaa ctttcctttc aacaaactca aaaacatgaa acaaataagc
     5641 gctatagaaa gtagaaaaaa ataaaaaata tattgttcat tatttatgtt acgacttgtt
     5701 cgaatcaaaa gaataagcat tgagacaaaa agaaactttc ctacaaccga tacgatggat
     5761 ataggtaaaa gccctttggc taactctgtt ctcggcattt tttttatagc aaaaaggata
     5821 ctgattaaac aaatcccata tatgcatgtt atcagcggcg gcgataaaaa actaatcgct
     5881 aacaaaacga ttattagtaa aagaaaaacg ataccaataa taatcgcttg ttgattttta
     5941 ttataaacct ttcccccgcc ttccacatgt agaaacaata aagtactcgt catggtagaa
     6001 attgtactaa ctgcaaaacc agaaactaac gcacttattt ctagccatct tgaactccat
     6061 ccaaagaaag taacactaag taatgatact atcagaatag aaacagtcca atataaggag
     6121 cggtgaatcc cagccttatt cacaataggt atccagataa acacacccgt catataagtt
     6181 gtataaaaca ggattgatgg ccagtatccc tcaaagcctt tcgaaatctg taatccataa
     6241 acaatgtaaa taagcatggg tgtaaagata gtcgttatta gtagactaaa tgtagttata
     6301 ctttgcacca caagtctttt ttgctttgtc gtatgtatcg tataacacct cacttaaaat
     6361 gaaatcagta gttgttatta cttattctgt ccggaacgag gttgttatat atgcgcaatc
     6421 caattgaaat tcccattacg aggtaaactc aatctaaatc cacattaaat taagtggcgt
     6481 gcaaaaaaga tggattttgt gattcttata aataaaatta atggatatat tcaaaacctt
     6541 aatcataaat ggaacaaatg tgttacttag attgtctatt acgtataaaa aaggtgcttt
     6601 tggtagttct ctcattttgt aatgcaagaa acacaagatg agtgctatcc tgtgcatttg
     6661 ttaattgtat aggtatgtaa aatacctata caaaatccat atattcttga aagaggttga
     6721 aaatgtatga tagtttcaaa gaagtttttt cacatcgcac attataaaaa gatgctccct
     6781 gtagtattac tttcatgtgc aacgcttata ggctgttcca atagtaatat tcaatccgca
     6841 ccaccgaaac aaaccaaaca agaaaataca agtaatcatt cttttgtaaa gctggaaaaa
     6901 gaatatgatg ctaaacttgg tatttatgca ttagacacag gtacgaatca aaccgttact
     6961 tatcgttcag atgaacggtt tgcatacgca tctacccaca aagcccttgc tgtgggagca
     7021 ctgttacaaa agaaatcaat agaagattta gatcaaagaa ttaagtatac tagcaaagat
     7081 cttgtgaatt acaatccaat tactgaaaaa tatgtagata caggtatgac tctgaaagag
     7141 cttgcggatg cttccattcg atatagtgat aatactgcac aaaatcttat tcttaaacaa
     7201 ttaggtgggc caagtgaatt caaaaaatca ctgagagaaa taggagatac tgtcacaaat
     7261 cctgaacgtt ttgaaccaga attaaacgaa gtgcagccag gagacactcg tgatactagt
     7321 accccaaagg cattagctac tagtcttcaa gcatacgcgc taggcgatat actttcagtt
     7381 gagaaacgga actttttaat agatttgatg aaaagaaata caacggggga caacttaatt
     7441 cgtgctggag ttccaggaga atgggaagta gccgataaga ccggctctgg gtcttatgga
     7501 acaaggaatg atattgcaat catttggcca ccaaataaaa agccaattat tcttgcgata
     7561 ctttctaatc atgcgaaaga agatgcgaaa tacgatgata aacttattgc aaatgcaact
     7621 aaaatagtgt tagacgcttt aaaagtaaca aataaatcat agtaatgaat ttaagctgct
     7681 cctactttac ggcacatata gttttaaata cttgtactta atctaaacgc taagaaatgt
     7741 aagcgtgttt tcaggcaaag aaggaggcaa aagcctccct cttctcctaa tcgaactctc
     7801 atcccattcc taaagaagac gacgccacat cgtagtggtc tttcaagttc gaatctccta
     7861 tttagagtta atattttacg tttcctttca tcttcaacca ttctaatgct caatcatatt
     7921 acgcatattt ttagattttc catttgtagc tatattaatc gagacattta aatctaattc
     7981 tttattttga agggatatcc ccccctcttt tttatatcgt ttccacaatt tggaattctg
     8041 ccgatataag gaatgtgata actgatacgt gtcaatccct ctttcgattc cttttcggta
     8101 cgttttttta atttcttttt caacttggtc ctctgcaatt tttttaatat catttacagg
     8161 catagaattt attaattgaa aaatatcagc atcgaaatgg atgttcataa gcatacgtaa
     8221 ctttccattt ttaataaaat gctttgtatc tatctttgga ttttttaata ctatatgtcc
     8281 aatgattttc ttgttaaatt ttaatagtaa tggagctcgt ttggtatttt catccgtcca
     8341 tcgaacccca gcaatatcat ggctgtttaa atgatttata taggatttat cgtttataaa
     8401 accataacca ctaaatttta acattggaaa tgatgtatgt ccttttttcc aatatgtttt
     8461 agtcgtagct aagaatggaa tgcgagttgt catcccaggt tcataataat ttctttggaa
     8521 tttatataaa ggtaaaggat ctattattgt atattgcttg gttatctctt ttggtaaatt
     8581 aatgattgta tataattgag aaatatttaa tatattattg ttcgctaata tattttctaa
     8641 aggctcctta gttccaaata tccacatagt atctcgaaat tgaaaaaacc gagaaaaaaa
     8701 atcattaaat tgatttaagt caccatgttt tagaaatctc tctgttacaa caattgtttt
     8761 gagatgctcc catgagattt cttgttgagc acccttataa aaatcaaatg ctgcctcatc
     8821 taaaatgggg ccttttccct ttccgatata ggcctggctg taattacggg tagtgctccc
     8881 ttcttgttta gctatgttag aaaaattaat aaattgcgga cggatgatat agttattatc
     8941 tttaaaatcg atacctagac tatttatata caaaacgtga tgcaactctc tttgatccca
     9001 acaccctgtt agaaacgtac acatcataaa aagaaatata actattcttt tatttttctt
     9061 catcggtact ctctcttttc cttgtattat cttgcgtatg caattcttta ggtctttttt
     9121 tcatatacgt gaaaggaagt ctaaatgtgg ctgctaacat acttttaaac acagggggtg
     9181 aatatggtgt aaagaatgga actccaaaag agcgtaaatt tactacatgt atcaccatca
     9241 caaggacaca aaagataaat cctactatgc ctaataaaga agatactaag aatactacat
     9301 accgcaatat acttattatt cctgttactg actgattagt taaagcaaat gtcgaaacaa
     9361 ccgagattgc tattataatg accatagatg ctgaaacaat tcctgcacta atagcagctt
     9421 gtccaataat taatccccct acaacagata atgtttgacc gaatacggca ggaacacgca
     9481 atcctgcttg tctcaaaatt tcaaataagg tcatcataat tatcccctct aaaggagctg
     9541 gaaaaggaat cccttctctt gataagctta atgtagctag caacgtatag ggaatctgat
     9601 ctggatgata tgtaattagt gctatccaaa ttcctggaag aaatatagaa attgctatcc
     9661 ccaaaagact tacaagtcgt acaaagctac cgaatatgta gaaaagatct tgatcttcag
     9721 atgtattcac aaaaaaagga aatgtaactg gtgcaattgt cgctgttggt gacccttcaa
     9781 ccagtaaaat aaaacgccca tatagcaaac aattcacagt ataatcaggg cgccctgtat
     9841 attcaactaa aggaaataca ctaaattgat tgtttgtgat taactcttca atttgtgcac
     9901 ttgaaacaac cccgtctatt ttaatttgtc ttaattttaa tcgaacttga ttaatgatat
     9961 cttgggatgc gacatctttt aaatacagga gtgctacttt agtttgtgtt ctttctccaa
    10021 taataaattc ttcataacta agagaactcg tttttagtct ttttctaatt aatcctatat
    10081 ttgtgtttaa ctcttcaaca aatccatcac gtccaccacg aatggtcatc tctgtatttg
    10141 tttgttcaac cgatctggta ggtatttggg caatatcaac tatatatcca tgtttagatt
    10201 cttcaaaaat aataaggagg ttaccttcaa atataatctg agagatagtt tcattcgaat
    10261 ttaccatatc taatttcttt actgataact ggggaattaa tgttgagagg ttaaactctt
    10321 ctattgaatt acttgaaagc tctttgcaaa catgggatga tgtggcttgt tttaattttg
    10381 tattgtcaat taagttttga caatacataa acaatactga attccttttt tctttctcat
    10441 ccaattcacg ctttattact tttacatcgt tgcatccttc aaaccactct agtattatct
    10501 tctcatttat ttctacttgt ttgttcatct acgttgtctc cttcaaactc agcaacctta
    10561 tataaaatac atccccatac tcttttaaga gcttttctta aatttagcaa cccatacaaa
    10621 cactattagt aagatagaaa acaaaaatag ccctaaagct gaaactggta aaataatttg
    10681 agatacaaac caatagaaac tagagtcact gatgggtagt atacttatta ataaaataca
    10741 tgaaagtatt gcaaacataa tcccatttct cgttttttga tttgtaattg ataacaaatc
    10801 tggtataaga aaaacaacaa gtgatagacg aataaagatc cctacaagcc actgatacac
    10861 ggagagaaag tctaaatttt caatgtacct tcctattgac acaagtctcc attcttcaaa
    10921 tgccggatac cgttggtttg ctgctacgaa aggtccaaat tctataatag ctgccataac
    10981 tgggcctatt gtgataccga taataaccat tcccaaagcg atcagttgat ataatttgac
    11041 ttttgaacaa atgtgatgct gtaagaaaag aataaaaatc aactctaaaa atcctgctgc
    11101 aggataaacc attcccttta atactggctt cattccattt tccatcattg gctgaagtaa
    11161 agaataatct ttatgcggaa catttgcaaa cattacaaaa aaaccaagta gaaatacaat
    11221 aggtaacaaa acacctgttg taagtgcaat agattgaatt cctcttgtag cattatagag
    11281 acaaatcatt gaaaaaagta ttcctaatac aaagtgaggt gtttctggta aataaaaaga
    11341 gaaaaaagtt aatgtttctt ttagtgcaac gacaccaatt gttattaaat aaatcacaac
    11401 tatgaatatg attggatata cactgagttt cccaaaatta ttttttaacc acgaaaacaa
    11461 gtgttcattt tttatgtttc tatatatgat gaatattaat gaaatccaaa tcaagtatat
    11521 aatgcttact aatatgatag agatccacga atctctacct gaggtatcta ataacatagg
    11581 aatcataatg acatgattaa ttatcccaat actaccaatg agtatcatag aaacttgaaa
    11641 taaagtaatt gtttgcttag tcatacatac caccatattt tgtaatgaat aaatattaca
    11701 tagtataact gatacattgc atctttattc caaatggtta gtgcttagag ccatggacaa
    11761 ttaaacgctc ttatttataa aatctatcac atgagatgta agctagttcc tttttacaga
    11821 taaataatta aacgggacag tatttagatc atacacctaa atactgtccc gttttttata
    11881 tgcaattctt caatgatata gtaaaccgat cataacaaaa agaacctgta gaatatacta
    11941 caagttcttt ttcaaaaatt gttaaaaagg gaataacaaa ctatcttaac attcaataca
    12001 gggagaccat tttaattatg gcttggttat attgtatatc aaatataaat atttgaagaa
    12061 actaatttcg aaaattatgt gaattaaaaa actagggtgt ttatattaaa tttcgtttac
    12121 taccaacttc tttttactta aatagactgc acggtctgat tttttagcaa cttcctgtga
    12181 gtgcgtcaca acaataatac atttattttc tttatgtgca agttcttgaa acagttctat
    12241 tatatccatt gccgtttctt cgtcgaggtt tcctgtcggc tcatccgcaa tcagtaaatc
    12301 aacattacaa gataacgctc gagcgattgc aacacgctgc tgttgcccgc cacttagttg
    12361 cagaacattt cgtttcgctt ctacttctgt aagtcctact ttctctaata attctaatgc
    12421 ccttgccgtt ttattttgca ctttaacacc tgtaatttcc attgctgtta agacattttg
    12481 aagagcactc atataggtaa tcaaattata agattggaaa attaccgata cattttgatt
    12541 acggtaccga tccaaaccaa tttttcgaat atcctttcca ttaaatagta cataaccatt
    12601 tttaggtata tctagcccac aacctaagct aagcgtagtg gttttaccag atccggatgg
    12661 tcctagaatc gtgtagaaat gtcctttttg aaaagaaaag ttaacatttt ctagtatcgc
    12721 tacttttttt ccgttacttt cataataata atctaagttt ttaaattgta aaatcgtctc
    12781 catatcgagc ctccttattc atcttttaaa agaatttgtt ttggattcag gcgtagaata
    12841 gataatgctg gaagaagcgt tgctaatata gcaatagcta gtccaatccc ccccattttc
    12901 cctacatctt cgccttttac acttacatta attttatcaa ttggatcctc tttttgattt
    12961 tgtacagttc caccaggtcc agctaccatt acagttccat tttgtgaggt gtttgtttct
    13021 tctcctgctg tagcaatttc actcgaaagt aaattattcc ctatgaattg agaaattttt
    13081 gctcctgttg ttatggataa tccaaatgct aaaatagcga tacatactac ttctactacg
    13141 aactgcgcca tcagtttcca ctttttctct ccaatggaca atagaatccc catttcctta
    13201 cgacgtgctt taatcgataa cataatgatt aaccctaaaa taatcgcacc tgcaattgat
    13261 acaatataaa taatcatttg agaagttgat gagatatttt cgataggccc aatcatttgt
    13321 ttatacaacg aatcatgtgc atctaattta taataattaa aatcaatatc agattttttt
    13381 gcttcttctt taaatgcttc aatgttttgt ggatctttca agaaatacac gacttgaatg
    13441 ctacttatac cttgatctat ttctaatttt ttcatagttg aatgcggcat atatagttta
    13501 ttagctggat ccattatagg aggagcttgt tgccccattg cttgctcatt cgtttcgtaa
    13561 ataccgataa tttcaacctc cagggtttcc ttcttatccc ctgattgcac tttaactttg
    13621 tctcctactt tcaagttgtt taattccgct aatcgttttt ccattaaagc tacattctga
    13681 tctttcatct gttctgtaat tggtttccca tcagtgattt tactttttcc attcttaaag
    13741 ctttcttgta atgcagtttt gcgaactccc tcaatcataa aagaagaatt catatctatt
    13801 tctgtaccgg agcctgaacc gcctcgtaca gccgccattc ccgccttacc ttttccttct
    13861 tcttctcctt ctgaagctcc tactagttta agtccgtcag aaattccgag agtgctagtt
    13921 atgtaattat agtcttttac atactttgac ttcgctaatt gatctgcttc ttttgtatta
    13981 agcttcggtg gattaggcat ctctccagtt tccctagctt gttgacctaa tttgtcaaaa
    14041 tcaagactta aagtaacatc tgcaccgagt ttttttcttg ctgcatcagc agcttttttt
    14101 gatgcatttt ggattgtgaa tcctgccaac accaaatttg taacaattag gaaaatcgcc
    14161 atcaaaatta atgatgttcc tactcttttt ttcatactga gaattgctcg tttcataaag
    14221 ttcatttttt cttacctcct tgataacttg tattctatat aggttatcta gagtctatat
    14281 ggagctaatc ggtagtttat ctagagatat aaggagttta tgtgtagtta ttcattgacc
    14341 tggtcaagaa agatcggaac acatattcaa aaacgtaatc gtttttgaat attggcaagg
    14401 aagttatggc tttagatagc attgaatgag agcatacaaa tccatgctta ttacgtaatt
    14461 tctatacaac aaataaaaac caccctattt gaatggttct atgtgtgctt gttaaatatg
    14521 aaaattcatt aaagaatatg gaggtttttt gaagttggtc ggattttcta ataataatat
    14581 tgtgttaaaa agcctaaatt ataattttat aagttaggct tttatgctat ctataagaaa
    14641 aagttataga gactcataat attttataat ttaacctatt gtatttaaac aagtaaaata
    14701 aaagtaacaa gtgcatacat taaggaggtt ttttgatagt gacagaaact ataacattta
    14761 ggattgcaac ggcagatgat ttagatgaaa ttgtaaaaat gcttgctgat gatgttttag
    14821 gaaataaaag agagcgctat gaaacaccac tccctgatag ttatataaga gcatttcatg
    14881 ctattgattg tgatccaaat aacgagttga ttgtagcgtg tgatgggacg gagattgtcg
    14941 gtattcaaca aattacattt acgccttaca ttgtacgtca agggggttgg agagctacaa
    15001 ttgagggtgt acggacagcc tcatcaaaac gtggtaaagg tataggaagt aaacttatta
    15061 aatgggctat tcaacgtgct aaattacggg gatgtcattt agtacagtta acaacagata
    15121 aagaacgaca agaagcttta cacttttata agaaattagg ttttaaagat tctcatgaag
    15181 gattaaaact ctttctctaa tgaatatagc tatttatata ccaaaaagac gtatattgta
    15241 aggttaatta actataggct tcgaaaatta tggtaactat cactgtatta aatatacaaa
    15301 ttgacacatt gtctttcata taaattacgt cacttcaaaa ggtgtacctt ttgatacgaa
    15361 aataagcaag ttaatgttct cttttatgaa tgagaatatt aacttgcttt ttaggttttt
    15421 gtaaaagata tttatagttt tattttattg atagctttat aatataatat acaaattccc
    15481 cacctgtttt ataattcaag catctactat taggaaaaga gaatatttta caattaattt
    15541 acagcataaa ttttgtccat cttttagacg atatgtattt tggaggaggt taatttgatt
    15601 ttttcaaaac tcattgatcg atacgccttg tatgatttgc acaaaaaaag aagtgtaaag
    15661 tttcagtata cttctctttc taacacctca ctatatataa aggacataga atttttttat
    15721 aaagtaaaac catctcatat tcattttaac attaagcatt taaaacaaga aaaggaatac
    15781 atggttggac aattcaaata taaaagctcg gttcaatctg gtgattcacg caacgattct
    15841 gtcactagag aattattttt acataaaaat gaaaatgcac ctcatgtcat ctttgttcac
    15901 ggttggagaa tggattctaa cgaacgtgta aaaaaaatat tccacgacca tatgaccaac
    15961 ttgaagtgga atatgtatta tttcacttta ccatatcatt ttgacagaaa accgaaccaa
    16021 tccctataca gtggagagta catggtaagt gccaatgttg aacgaactgt agaagcaact
    16081 agacaagcgg tagctgattt acgaactttg atcaaatgga taaaagaaaa taaaaatggt
    16141 cccttgattt taataggaat cagtttaggt ggagttatta ctaacttaac atctcttgtt
    16201 gaaccagaaa ttgatgtgtt agcatccatt ttctacgcga atcgactctc atattcaatt
    16261 tggaagacaa atccaggtaa ttttattaga gaagatttgg aacatcatgg tgttacgtat
    16321 gatgatttaa tagcttattg gaaaatcact gaaccgagtc aagcgttacc aaaagtaaaa
    16381 aaagaaaata ttttattaat ttcaggtaag cacgatctat atgtgcactc tgaggatacg
    16441 gactatttgt gggaatcctg ggaaagacct acacgatata tttatacatg cggacatgcc
    16501 gggattgttc ttaaacgtaa aaaaattgca actgatacta tcaattttat tcagaatcga
    16561 ttgaactcct cacacttccc caaagacata ccttaaagtg agggattact aagtatagaa
    16621 tcttatactt gtaatctttc attttatacc aagttcattt catatggaaa agggttactc
    16681 atcattttca ccaggggctt atttttataa aaagaaatta ttgttgttta ccctttatat
    16741 gcaatattac atataaaaat ctttaattgt tctgttataa ttttaagagt aaattatgca
    16801 tccattaatt tacaccatcc atatctacag ttatggaaac cctaattaca tataaaaaag
    16861 agaagaactt tggtgagttc ttctcttttt tatatttttt taagattact atccaaagta
    16921 attattgcaa ttactttaag ctggcttttg aattataaat tctgattttc atacttcttc
    16981 atgagtctag ataagaaaaa agaatctact ccttttctag ccaaataaaa gaattttttt
    17041 taaacagtta ttttaatttg tactgttttc ctatattaat gcctgcccat gagtatttcc
    17101 ctgaattata tattaaggaa tgaaaatgga ttaattcttt ccgagtatga attcgaatag
    17161 gtatcacttg caatatgtca ttaaaataaa aaggattatc acttggttta attagaagac
    17221 taagtgtaca taaatacaac gacatgaaaa cactttgctc ctaaatccac tacttgtatt
    17281 attggttgtg tgaaactcct tcttgagaaa ggctttaatt tccgaatatt ctgttgactg
    17341 ttatcgcata tccaatttac aatttaattg tgatattttt tcacaattaa actacttaga
    17401 atacacttca tttattcgaa aacaattaca aatagaggtg ctaaaatgaa aacaagagta
    17461 aatccagagt tattacaagg gttagagatg tttccaaatc tcgatttaca cccggaaaac
    17521 ttgcaatcaa tcagagaagg aatagctcaa atgagaccac ctaccgttgt tgatgaatcc
    17581 ctttcgttaa cagatgaagt cattgttgga cctgatgata atccgttacc attaagaatt
    17641 tatcgtccaa aatcaaataa tgaaccttta cctgtcttat tatggataca tggtggtggt
    17701 tatatcttag ggtctataga tgataacgat gatacttgta tgaggtttgc aaaagaagct
    17761 ggctgtgtgg tcgtgtctgt agactaccgc ttagcacctg aacaccctta cccagcacca
    17821 attgaggatt gttattcagc tttaaaatgg attgctgata atgcgaagtc attaaacatt
    17881 gattcgaatc gaattggggt tgcaggagta agcgctggag gtggactaac agcagcatta
    17941 tcattattag cccgagatcg aaaatatcct tcaatttgtt tacagatgcc actctatcca
    18001 atgattgatg accgaaataa tacaccttca gcgaatgaaa ttaaagaagg atttgtttgg
    18061 aatcaaaagg caaatgaagc cggttggaaa atgtatttag gagaaatgta tggaacagat
    18121 caaatccctg tctatgcagc gccttctcga gcagaggatt atagtgattt accatatact
    18181 tacacatttg ttggtcaatt agatccattc cgcagtgaaa cattaaccta tgtaagcaaa
    18241 ctagcgcaag ctggtgttga tgtcgagttt catttatatc caaatgccta tcactggttt
    18301 gaagggttaa atccaaatgc cgatgtatct atttacgctg taaacgaaat ggtacaagca
    18361 gtaaagactg gtttcaaaag agtctctaag gttgaggctt aatcccttta caagaaaaac
    18421 actcgtaaat agtataatag ccgattctca tttagaatcg gctattaata tgtaaaattc
    18481 acctaatata tcaaggttga gaaacagata taagatgttt aggcgatgtg tttatttcct
    18541 ctgccaacgc cttaatgctc atcatgattt gaagtatttc ttctaatgtt gtcctcgggt
    18601 tgatagagca aagtcgaatt actacttttt cttttaattt agtcgtactt agcatagcaa
    18661 atcctctttg attaatttct tccaccagtt ttttgtttat ttcatgaatt gtttctgtag
    18721 acgttcgctt acaaggaata taacgaaaag taacaattcc taattgggca ggtgttacta
    18781 cttcccaatc tttttctttc cttaaaaact cttcaacttg ttcagccaac ataatgccat
    18841 gatctattgc ctcacgaaaa gctgtgactc caaatgcttt aaaagaaagc cataccttta
    18901 atgccctaaa tctacgagaa agttcaattc cacgctcccc aaaattcact ttttcttcta
    18961 tattagtttc tgtatcctta atatactctg ggatcatacg gaacgtttta cttaaatatt
    19021 ggctattgcg aatgagtaca caaccaacat cataaggctg aaaaagccat ttatgcgggt
    19081 ctaacgtcaa agaatcagca cgatgaattc ctcttaacac ctcccttcct ttttcactga
    19141 gaattgctgc agccccataa gcaccatccg cgtgtagcca tacatcttca tcaccacata
    19201 gatcagccaa ttcatcgagg gagtccaccg ctccgcaatt cgttgtccct gcattagcaa
    19261 taacacaaaa tggttttttc ccttttaatc gatcttcttt tatttgcttt cttaaagtac
    19321 taactgaaat tcttaaatct tcatctgttt caattcggca aatttgatga tgtttaaaac
    19381 ctaatacttt aagtgctcga tctacagaaa aatgagtttg gttagaaaaa tacacaaccg
    19441 cattttctat gtcattattc agcttgacct gtctcgctac agtaagtgca gtcaaattag
    19501 ccatggaacc gccactgaca aatagccctt cagctgaatc agggaatcct agcattgatt
    19561 ttaaccagtt gattgtcgtt aattcaattt gttcagcacc tgcacctact atccaagctg
    19621 taggaaatac attaaaccca cttgctaaaa aatctgctat tacaccaaca taattattag
    19681 gacctggcac aaaagccata aaatgaggat gatccacatg agtaatttga ttaaacacat
    19741 tgttattaag aaaatgaagt aactcttttg gattggatcc gttttctgga atcgtttcaa
    19801 ttagcttgtc tctaaaaata ttactatcaa tcgtttccga aactggttta ctttttaaat
    19861 gattcatatg atcaacaatc aagtccaccg cttgatatcc taactgacgc atctcttcgg
    19921 ctgataactg caagtttttt gtcatttggt ttactcctat tctatttaaa aaggcgagtt
    19981 cttgctcgcc ttttcatttt ttataatttg taatcaccga ttgcctgtat tggattttga
    20041 agaatcatgt tgattaactg atggatgtga ttcaatattt cctgtatttt ctccgcttca
    20101 tatacggttt gatcatatcc aaactttatt gtaagtttct cttcagggaa gcacataatt
    20161 ccatacttta catgaggctc atcaacaact tcgtaatctg tgatggcaaa atttctgttt
    20221 tcatttgaag aaaagatagc tgagttagtc ggatagtttt caaaaaccca aagatggtca
    20281 gtcaactcag tttttaattc actttgtttt tgtatatcaa caaatgaata gtatgcatac
    20341 tcattacatt tcaatgtttc tagttgtact ttttgcagga agtccacaaa agattgcgtt
    20401 tctgtccatg ctagtcggat aggcaaaata tttgtgaaca gaccgaacat attttcaatc
    20461 ccttctactt cgggaggtct gactgatact agattaggta atactacttc tctcattccg
    20521 ttgtatttgc caagcaatat tccccataca gctagtaatg ccgaattcat agttatattg
    20581 tttttagtta caaatgtctg taactgatta gtcaaatcct tatctaatgt taaatccata
    20641 aatgtgaaat ttaacccttc actttgagtt ggtactttct ttttaggaat actaattttc
    20701 cgattgtatc ctgataaata atcccgccaa aaatgacgtg ctttctcatg atctcgtgct
    20761 acagtccaat ctatgaatgt ctcaaaaggt ttcactatag gtaactctgc cgtagttccc
    20821 gcatttattg tttcatagag ctggaataat tcgtctatca aaatgctgac gctccaacca
    20881 tcacataata gatgatggga actccaaacc accctatgct cgttattttc tagttggaat
    20941 atacaaagac gggtcatgag ttcatcattt ttgaatcctt gacttaaatt ttcattcatc
    21001 cactggtcta ggaattcttg ctgttcttgt ttcgtcatct caatcaagtt ttttatctct
    21061 gaaatcattt gaacatcatg tagaacagct tgccaaggtt gtgcttgttc atcttgcaca
    21121 attatcgttc ttaaagaatc atgacgatca actaattgtt ggaaacactg aataaagaga
    21181 ttaatatcca gctccccctc aagtgcccaa attgtttgtt cgaaatatgc atttgtatca
    21241 ggttcagtcg cagcatgttc ataaataact tcctggaaag gtgccaatgg gtaaatacgt
    21301 tctattttta tttctggcat tttttcttgt attttgataa gtgtatgttg attaagttgt
    21361 ttatctttaa catttagtac tgtaacttta ttatcgttca ttttgtttac atcacttgtt
    21421 tgcgaatttg gaagatgatc aagcttttta acaaattgaa ccatgtctcc taatatagga
    21481 aatgaaaata aattttttgg ctccagctca aatccttgtc tatacagtct gacggaaact
    21541 tgaatcgctt ttatcgaatc tccacctaag gcaaagaaat gatcatttac tccaatccga
    21601 tttactttga gtacttcttg ccaaacacta gttaatattt tttccatttc cgtttttgga
    21661 gcaataaata cttcatttgt ttgtttctcc ggagtaggga gcgcttttct atctaatttc
    21721 ccgtttggag tcaagggcaa ttgttccaaa taaacaaaat aagaaggaat catgtaacct
    21781 ggcaagtgat ctcgcaaatg ctttcgaagt tctgttgtgc taatattttt ctcagttacc
    21841 acatatgcga ctaaaaactt tataccatac tcatctgtct gatcaatcac tactgcatgt
    21901 tcgacttgtt tgtaagtgag aagacaatgg gcgatttctt ctaactctac tcgatatcct
    21961 tgaattttga cttgataatc ttggcggcct aaaaattcaa tatatccctc aggatgcatt
    22021 tttccacagt ctcctgtctt gtaaataaga ccaaaatcag gatgtgatac aaatgcttca
    22081 tttgttttct gttcatcatt taaatatcct ttagcaaggc ccactccccc gatatataaa
    22141 tctccaatta caccaacagg gcacattttc ttttcatagt tcaacacata atacgtttgg
    22201 tttgccaaag gaatcccgta tggaatactt ttccaatgcg attccacctg tttgaccgga
    22261 taataaattg accaaatcga tgcttctgtt gctcctccga gtgaaactac ttccgcaatc
    22321 ggaaaatgtc gttttatttt ttctggtaaa gaaagtggaa tccaatctcc actatgtaaa
    22381 actaaacgca aggaagaatg ttcaaaatga gaacctactt gatctaatgc caaatccata
    22441 attgcaggta ctgtattcca aattgtaatt cctctacgtt cgacagtacg gattaattct
    22501 tgcatgtctc ttgggtcacg aatcattacc aacattgcac ctgtgcttaa cgttccgaaa
    22561 atatcgtata cagataagtc aaaacacata gaagaaatac caataatacg atcatcttca
    22621 tttacctgat atttttgatt aatatcttga atggtatttg caaccgcttg gtgagtaata
    22681 attactcctt tcggttttcc tgtacttcct gaagtgtaga taatataggc aagatcttcc
    22741 ggaccagcaa tagcaggcat atcttctgtt gtgtataatg acaagcggtt ttctgcataa
    22801 agactaggtt ctaataaaag tttgcatgag ctattttcta aaatatatgt ttggcgatct
    22861 gaaggatggt cgggatcaat cggaacataa gcggcacctg cttttaaaat acctatcata
    22921 ttaacaattg tgtcaactcg tctttgtgct aaaagaccaa ccttgtcacc tagaccaatt
    22981 ccttgttctt ttaaaaagtg cgcaacttga ttggagcgct tatgaagctc cgagtatgtt
    23041 aagtagtctt gttcaaaaac tactgctact tcatccggtg tacgttttac ttggtctgta
    23101 aataattgat ttaaagtagt cgacggtatt ttttctgttg tctcattgta ttgctcaatt
    23161 aaagcatggt ctaactcttt catttgcaaa gatgttacgt cactttgttt cactaattgt
    23221 tccaataagt caacaaattg gtgaaacatc gcttctatca catcaacatc aaacaattct
    23281 tcaacatagt tccagctaat taataactct ccattttttt caattaccac attatccaaa
    23341 tgcacttgtg gagtccgagc atgaatatgg cgaagtgaac caagttgttc ccaagcaaaa
    23401 gcccccgcac ctgctagcat cgaagtgaaa acaattggca taactgcttt tggcgtcatt
    23461 tgatgatatc gagtaaaatc tcgaatgaaa ttaactccat cgtaatggcg atgttcgaga
    23521 ccatctaata aagtagattg cgtttctttt actctagtaa agaaagattg atctggattc
    23581 acatcaacat ccaacaagat gagtgaagtg aaatctccca caatttgctc tacttcttca
    23641 tgaacaggat aacggttaaa tacagtcaaa ttaattgcca atcgacgttg attactccaa
    23701 tatgccaata catcactata tattgtacaa agcagagccg aaggagttac ttctttctct
    23761 tgtgctaact ttcgtagctt tgtccatatt tcattgtcca ggatcttatt aagtgattgg
    23821 aacttaggag tagcaatctc tgccggatcc ttttttaaca gcaaagaagg cgcaaacgga
    23881 aagtcaggaa gcttacttgt ccaataatct tttgctgttt tatattctgt actttgttcc
    23941 agttcatcat agataaacat gtaatcttga aaatcaaaag atagaggttc taacctttgc
    24001 tctggtttat aataataatg aaacaaatcc tgtccaacga tgttcatgct tgctccgtcc
    24061 attaataaag catcgtatcg aaaacataat aaatacgtgt cttcttttaa aagaaaggct
    24121 tttaattcaa acaaaggcca ttgccctaaa ggaaatacat gattagtcat tcgagaacgt
    24181 tcttcttgta agcgagcatt ttgattccta tcatctaaat ctatgagact tactatttca
    24241 atctcgtaat caggaacgct ttgtaatatt tgctgttctc cctctggtaa aattacagct
    24301 cgtaacatcg gatgacgttg aattaccttt tgaaaacttt ttgaaagacg attgatattc
    24361 aattctgttt catattcaaa ataagtttga ggtgaaatac cacttaattc aaactgtgaa
    24421 ttccgtccta acatgtacgc tgtctgaacc tctgttaagg gaaatggctt agacaaatct
    24481 ttaacatggg ttggtctatt ttcaaagttt tccgttttat gctctaactt tacacaagta
    24541 ctaagttgag caatcgtggg atgcttaaaa aaatctgttg tacttatttt taagcagtct
    24601 tttcttaata gattaattac ctgaagtgct ttaatcgatt ctccttttaa agcaaaaaaa
    24661 ttatcatgaa taccgattcc ctcaatctcc ataacttttt cccatgcatg caccaatttt
    24721 tgttcaattt cattgcgcgg ggcaacgtat ggaattgata cataatctgt ttgtgttata
    24781 tctaataacc ttttcctatc tactttccca tttggattca acggaatctc ttccacctga
    24841 atcatttttt caggaatcat aaactcaggt aatttatcac ttaaatattt tctgatttca
    24901 tcaaaagaga ccttattatc cgatacatag tacgcagcta ataatttcct atttccatat
    24961 acttgatcaa caacgatagc ttggtttatt tctggatatt cccttaactg gctttcgatc
    25021 tctcttaatt caatccgata tccccgaatt tttacttgat gatccattcg acctagatat
    25081 tcaagttctc cattaggcaa ccaacgaacg agatcacccg tatgatacat catttctcct
    25141 gccgtaaagg gactcggtac aaacttttca tctgtcagtt tagatttccc aagataccct
    25201 cgtgctaccg ccacgccacc aatgcagagt tcacccggaa ttccaaatgg ttttaattga
    25261 ccatacttat tcaatatata ggaatgataa ttcgggttgg gacttccaat cgtaacttct
    25321 ttggcagagc tcaaatcctt tactgttgca caaatggttg tttctgtagg accataaata
    25381 tttaaaattg tcgcttcact gatgcatcgg attttttcaa ccaaatcaat ggaaaatgct
    25441 tctcctgcta acaaaataga ttttaaatct tttagaaaat ttgccccttc tggatcactc
    25501 aaaatcactt ccattcgcga tggcgttgat tcccataaat ccaccttatg ttctttgacc
    25561 aaataagcta attcttttgt tgcgaactga tcctctgtag caataactac tttcgaacct
    25621 tgtgttaaag gcagacatat ttctaacaag gagatatcaa aagatacact agcaagaaac
    25681 aagaatgact gattatcttt tactttttct ctcattacac ttaaaaaatg gacaagagat
    25741 ttctgttcta ccattacccc ttttggattc cctgtcgatc ccgatgtgta aataacataa
    25801 gctaaatcat taggataact ttctcgaact aaattacttt cctcaccttg gaagagatat
    25861 tcctcatcaa gatacagcac ttcacccgca aattgcggca attctacttc tgttcgcttg
    25921 ctcagtaaac atttcgcttg actatcttgt aacatatatt caattcgttc atttggatag
    25981 ttaggatcga ttggtaaata cgctgctcct gcttttaaaa tccccaccat gccaatgatc
    26041 atttccaatg accgatctac cataacccca ataatacttt ctttggaaac acctttactt
    26101 tgaagaatag aggccaattg atttgctttc ttattcaatt ctctatatgt caaagattga
    26161 tcattacaaa caacagcaat ttgatctggg gtttttaaca cttgttcctc aaacaaattt
    26221 tgaaatgatt gagacaattc tatgtccgcc tgaccttgat tcaattcttc tagcaactct
    26281 ttctcttctt ctgaaatgat acaaatatct ttcacagcca aattcgaatt tgttgacact
    26341 tgctttaaaa cataaagata tgaatttgca aactgttgca aagaagagaa tgaatgagac
    26401 ttgaaagaaa tttgaatttc aaattcatta tgtatttcat tccattctct ttgtatccag
    26461 atggctaaat tattctctgc atattcttct atcaaatttt tattatgtaa tccttccatc
    26521 ccaataacaa tttgaaaagg agttaaatgg tgtttcgcta ataattcaga gagtggataa
    26581 ctctgattgt catacccgaa taaagtcgtt tgttcaatct gatttactac ttgtttaaag
    26641 ctgtgatgcg gatagatttc acttcctaaa ggaatcaact tattaagatt ctcgctttgt
    26701 tcaatattct tttcaattac aggaatacca atagtaatcc tttcttgatc tgtatagtgt
    26761 gccaaacaaa tccttaacgc ggcctgtaac cagctaaata ataataaatc ttgagactta
    26821 attacttttt gtatactttt actaaactct acattcatta tgacttgaac gtgctcgtaa
    26881 ggattttctt tatttagttg gtaaccgcta ttaaatacag aaaaatcgag aacctcggaa
    26941 gataactgct ctttccaaaa cgcctctacc cctttatttt catgaatcga acttcgatct
    27001 ttaatgtgca tttttatctt tatcccccta atattcattt catctattcg ttaattttca
    27061 agccaacttc aagcccatgg agaaatactt gatggttatc caaacataaa aattgctgaa
    27121 tctcttcaaa tttcatatga ccaactgaac aaacgcctaa attcaatgtc tcagccacca
    27181 tatttaaggt agcagtgata ataccagact caatacaagc aaataaatat ccatctgaac
    27241 cgtatttcgg gatggaagcg ttcgcattat aaaccaaata aactgaaaag gcagactgag
    27301 taaataaatc ttggttaatt aactcatgat cacttttgat tacttgatca atattattta
    27361 caatcacaag acagtttttt gctgggttat aataataaaa cccagctttc ataccttcta
    27421 tacgttttgg ttttatataa ataaagatat caatagggta gagtccgcct gcacttgcgt
    27481 aatgatagta tatatgttct ttcctaacct gttttagagt tgatatgaat tgggaaaatt
    27541 ctaaaaaact aatatgtttt ttcatatcaa attggcgaca agacctacgt tccttgatta
    27601 tagtgggtaa ctcatttgtt gtttcaagtt gaatttcggt tgaccgcaca gcatggtgtg
    27661 ttcgattcaa ttgttcactc atatacttat ctaaatcttc tttagaaaag cgaatctggt
    27721 tgctatatgg attcggaaaa atcttttctt gtgtggaaaa tacttctctt gggtgtaata
    27781 tgttacttac taacacacga ttttttatca taagctctac tgttttttgt gtctcttcta
    27841 catttcctaa cgaaaagtgc tctactagtt cactaatttt cacacctttt tgagtaaaaa
    27901 aataaaactc aggaaaccac tcagacaaaa cgcctgtaaa tcttgtttct cctatcaaaa
    27961 tttcattatg caacttctcc caatgcttaa taggagacca gtaataaatt tgctcgctca
    28021 tataaccctc cataaacgtt ttacttattt ttaaaataca attttctaat ctacaaaaat
    28081 agtccttaga ttctgccctt tgtttcatag tgattataaa tacatgtact tcaacgtaac
    28141 ttgagaataa tgaaataact ttttcttcat tgaaattttt tatttcgtca taaaaaatga
    28201 ttttttatta gacattttac atcctttccc atagtaatcc tataaggtat aaaccatttg
    28261 gaacattgag aatttccatg tattttcaat gtgaaattat tgtaatggat tggaaagcag
    28321 atggaaatag ttattaaaca aaataatatt gagaaagttt tatttgttat agcgataaaa
    28381 ttttctaatg agatttatta caaatagatt aagaaaagaa tttgaaattt ttctttagaa
    28441 gttagtgtaa aaatgcacat actattacat acaagtgagt tattaacata tcgtatttaa
    28501 aatagagaaa agacaccatt ttaggtgtct tttctctatt ttaattccat atacttttac
    28561 gcctttgtta tttttcgaac gatttgtagg aattaatata actcgaacat ctagctcgtt
    28621 agatgttcga atgtatatta aaaattatat aaattaagaa tgtatttcag ataattttat
    28681 aaataaatac aaaggtacct cctcccctac tgttacaata gcaataatct cttgtctatt
    28741 tccgttatta aattgtaata taattacagt atgtgaaatt atactacatt aactttaaaa
    28801 gcgaagtgaa aacaaccttc acttcgcttt tttcatttgt aatccctatt caatttgctc
    28861 aattcagtat atactttcac attatttgct tttatttatt cggtttctct gtttttaaaa
    28921 ctagtgaact taatgcagga actttaattt tattgtcatg gacaacgtaa agtgttttac
    28981 ttcccgcctg attctcgttt actagcactt tccatggacc tttcgatgga agtgttatgt
    29041 caacggcttc cctatttgca ttgtgagcca ccataaagta ttcgctttta ttcccacttc
    29101 cctttccatc tattgtataa gctacaacat ttttgggaac atcgataaaa gctacatact
    29161 ttttaatttg ctctgcagaa gtcatacgaa aagctgggta tttttttcgt aaatctatta
    29221 agcccttcat atactctact tcattattaa atgctgcacg gcgtaaccaa tccatctggt
    29281 taatagaatc aggagatttg taactattat gatcaccata ttttgtgcgc ataaactctt
    29341 gtcctgcatg taagaatgga ataccttgtg atgttaataa aatagaagaa gataatttat
    29401 gcatttgttt tcgcatttct tcactgtcac ctgaattagt caactcaagt ttatcccata
    29461 aagtatgatt gtcatgtgct tccacataag ttagcacctg ctccggatct tgataagtag
    29521 acgaatttgt atcatagtca ataccggctg taatgccttt tttaatacgg tcttccatgt
    29581 tttgctttcc atttacaaaa ccattttctt tctcctcaaa tacactacct ttcaatccat
    29641 cacgaatatt atcgttaaaa tgagcaatcc ctttcatttt ctccgcattt ttttgatttg
    29701 ctttcaattc agctgcaaga ggtgtattta aatcccagcc ttctccatgc agaataatag
    29761 aaggatcaat ttgattaaca gctttacgta tctcattcat cgtttcataa tcatgaatac
    29821 ccattaaatc aaaacggaac ccatctaaat tgtattcttt tgcccagtat gtgacggaat
    29881 ctaccataaa ttttctcatc atctttcgtt ctgaagcggt atcattccct actccagttc
    29941 catttgctaa tgttccgtct tcattgtaac gataatagta acctggaact aacttatgaa
    30001 aatttgattc agcggcatta tacatatggt tatatactac gtccatcaca acacgaagat
    30061 tattatcatg caatgtttga atcatttgct ttaattcagt tattcgaaca gttggctcaa
    30121 aaggatttgt agaataggag ccctctggga cgttgaaatt ttccgggtca tatccccagt
    30181 tatattgtgg ttcatttaaa ttctcttcat ttactgaagc ataatcaaat atcggtaaaa
    30241 actgaacgtg agtaacacca agatctttca tatgatcaag tcctgttttt acaccttcag
    30301 gcccttttgt tcctttttct gttacaccta aatattttcc tttttgctta ataccacttt
    30361 caggttggat ggaaagatcg cgtacatgca attcataaat aatagcatct tccggatttt
    30421 taaatttcgg ttttttgttt gctttccatt ttttcggatt tgtttcttct aaatcaacaa
    30481 ctgcaccttt atctccattt acagaagcag cacgcacata cggatcaacc gcttcagtcc
    30541 acttatcccc aattttcacc ttatacgtat aaaagagacc tttttggttc cctttaagtt
    30601 ctgctttcca agttcccttt tcaccttgtt tcatgtttat ttcagtacct attttatcgc
    30661 tccatttttt atatgtaact aacttcgctt cactcgcagt aggagcccat aaacggaact
    30721 ttgtatgttg cggagtatat atattcccta aatcattacc accataataa aataaattat
    30781 caaattcctc gctacgaatg actttaccga tttcagtatt cgcatcagct aagtttgcta
    30841 ttttaacttt gtatgtttgt tttaaatcaa ttttctgttc cgtaattatt ttaaccttat
    30901 tagtaatatc tccactattt ttatcataag gactaattcc cttaatttta acgccttcaa
    30961 tttcaatttt ctgttcctta ctattaaacg gaacattagt cgttacagta atttcattaa
    31021 aactatcaat agtagctttt tgaattgaga gatccgaaga aggcttagaa tcatatactt
    31081 tttcatcacc cgaaaggatc catacttcag cacgaccatc ccttatattt tcaacccagt
    31141 gatcacctcc atctttttcc cattcattgg tacgaactat aaaccctaca cgattatagt
    31201 caccacctat ttttatctta gcgtattttc caaattcatc ttcaccagta aattcataag
    31261 atttaccgtt tgcattttct ccccataccc aaagattcca gtcttttgta tttccagatt
    31321 tctctttgta atgaatgata acttcagttg ttttcgaatt tgaaactgcc ttcacactct
    31381 gaaaagagaa aacagatgat aacataacga ttatggtaag taataaaaac gatttgttaa
    31441 ttaatttttt tgtaatttgc accccataca ccctttcttt aaatattacg aacaatttat
    31501 tatgctcata ctacgaaaca cggtttaaat taatctagga atctctttta cttcacctcc
    31561 atattggcta tttttacgta tgtatttcaa tgatctttta tacgaaaatc aaatataaga
    31621 tggaaacaac ccttacgaaa acgtttgcat taaaactcaa aaaaatagat ttgtttattc
    31681 cttcttatat ttgtaaatac taaaagatca gggaaatcat tttaaagcaa tcgtttgtta
    31741 tcgctttcat tttatagcac ttactattaa aaggtcaata tattattaat tttctgtttt
    31801 tatatccttg aaatcttata tatttgtcgt aacttattga agatagatgc ctgattattg
    31861 cttagtaatt ttattttcac taatacattg ctacgtaaaa aatcagctat atccttaaaa
    31921 tgacattagc tgattttcat aatgtattaa tatatgaatg aaaactatat ttctaactta
    31981 cttaattttt gctgcatcaa atgctttttg cactgcttga acttcagctg tattcgcccc
    32041 atatttatta gttgccactc gaatacatgc tgatttcaat tctttgaaat tagatgtcat
    32101 gtttaattca tctgtatttg cataatagaa aatatcaaac attttatctt caccaattcc
    32161 tttaacagtt actccgttat gagttccacc ttttgcaatg agatacgcaa ctttattaat
    32221 aatacttgaa ttaaaatgaa cgccgccttg atcccatcca ttaaaatcgt taaattcact
    32281 gtaatcatct ggataaggta ctccaagtga agatggaaca gaagctgggt tttccatatc
    32341 acggaaaaca gatccagttt gttctcccat tgtccagtta aagcttccat tatttacgta
    32401 tttctcaata gatgttccca taatatcaga tagcgcttca ttaatcgcac caggttcacc
    32461 gtaatattca agattagatt cgctagaagt aacagcatgt gtaaattcat gtccagctac
    32521 gtcatatgcc ttgacaatag gatcgccata tacaagcata cttccattat tagcacttaa
    32581 tgcattttgc caatttttcg gatcgttcgt atcttcagaa tcccaagcat gtacaactga
    32641 aactaccttt tgtcccttat tatcaaaact attacgctta tatttatctt tataaaaatc
    32701 aaataccttt gttgctaaat aatgagcact tactgctttt ggatcgttaa atgttgttga
    32761 agtgctggtt gctagtgtac caggataata gctttcttct ttagtaatat ctctgtaatt
    32821 cacatcatat gtttcaattc cttgccctct tgtataatca gcaagtgcat atttaccatt
    32881 actttgttta gaaataccaa atgaacgaga tatacctaaa tcatcttttc ctgttccagt
    32941 taatgatgta agactacttt ttttactttc ctttaaagct ccaactagtt tttcacttgc
    33001 ttttaagtta gattcttgta ccatattttt taacatatca ccattttgtg catttactaa
    33061 ataagttcca gaaacatagt ttggtgttgc cgcttcaaat gtaacttgat atgcattgct
    33121 agcttgtcca ttattttcat caacaaaaat aacttcctta acttctggct cagaaataaa
    33181 cttgatatcg ttcccgtatt tcgtataaat atattgtttc gcttcatctt ttgatagatt
    33241 aataggcttt ttcaattctt cttgttttaa attttgcgcg ctatcgcctg aaacactttt
    33301 aataacaccg ttattatcta cgtgtgcagt taattgatgg ccatatactt cttttccttc
    33361 gtatgtttgc tgcatacgca caagtgttgt tccatcatac gaaccacgtt tttgaagaac
    33421 tttataatct actcctgttt ctccattgac ttgatttgga gaaagagctt gttcagcttt
    33481 ctccttaaga gcatctttta ctacattctc tggtgttttt tgtgacggtt gtgtaagttc
    33541 acctgaacgg aatgagtcct cctgaatttg aacttgaagt tgatctgttt cctctgcatg
    33601 acctattccg tatggtgcca cagctgttaa agctaatcct gttgttaatg ctactttagt
    33661 taatgtcttt gtgtttttca ttttttcacc tcgtataatt tttgaaatag aaagcttgta
    33721 caaagtatac tgtctattta tgtcgaaaaa aagagaaaat acaaaattta tgtaatatta
    33781 tgcaaaatta catatatgtg gtcgataaaa taaaaaatga gcccttttag gtgctcatcc
    33841 aattggttag tcgttaatta tctatattca ttctaatcaa agtacactta tatcttatta
    33901 acaacataaa aaaccactct ttactatttt aagaatagta gataaatact ttagtgaggc
    33961 aacgcatata caagttagat ttttcaatat aattttgtta tttatgtcta tagctgcatg
    34021 gattgtaacg ttttgagact gctgaagtct tatatgagtt tcaggctttt ttatcttgtc
    34081 aaaaatatct ttcaaagata tttttgtctc cccatttaaa tatagaaaag gacatatcta
    34141 ttgcatgtta ttaacttaag gtatgttctt ttaaagcata ttataaatat acatagtgag
    34201 aaatgaaaca ataattattc aaatgaaaaa tcccctaaat ttttaaagcg attcagggga
    34261 ttttttaccg atgattctct atatttccat accgatcaca aactttttta ggataatggt
    34321 atgtccaagt ttaatagttt tttgcacgag agccatcttt tttatattta tttaattatc
    34381 ctactaagtt ttttgtaaaa ttcacctttt ctttttacat gattaaactg atttggatta
    34441 atattagctt tttgtgagag tgctacaatc tcttcttttg taattgaatc tttagtattt
    34501 atagatgcta tatttgtata ttttccatct tctgtttttg ggatttctaa aatcccttta
    34561 tttacaagat caactacagc cttatgctct gaagaatgtg tatctacacc agtaattttc
    34621 caattatgca taacttttgg cgtgtataca ccgttcttta cctcttttaa atatgtaata
    34681 gcaaggttac gaatggttcc acctgtttct ccgaatgcat tctcttgttt agatgaccaa
    34741 gtttgttcaa atttacgtcc ctctaaagct cccccttttg cctgaagagc ctccattcta
    34801 tacgcattca ttcctagcgt cataacatcg ctcattttga ttggtttatt tgtacgaata
    34861 gagcgtaaat ttgtaattct actaccatat ggttttgtta agtcaatttc gtattttacg
    34921 cctccaaaga aatcgttcgt actgtattta gacgcacgac gatttttatc aaagctaact
    34981 gttacatctc cggcacgaga tgagttaaaa tatcctgctg cccattccat atagtctttc
    35041 aaatcttttc cagttatctt atatactgta atttctccca aagcatattg ataattataa
    35101 gcaatatctt tcttctttat aggacctata tccaaacggg cataatcatt atcaatttga
    35161 tgggctacta catccgcctt actgtaatgg agcatgactt catgaaagaa atctgataaa
    35221 ggtgtctctt gaatctgcac acttggaata ccctttattt cattttcagg aacaaggttt
    35281 ctacccttta attgggcgac tacaacattt gcatctcctc tcgcatactc atgaaaaggt
    35341 gttagtgttt cttcaagtgt agaatcagat aatactgtag ttccatcagc attttttaca
    35401 ggtatagcgg tagctgtttt atcttttaaa acaagcttcc catcttgctt tgtaaaagta
    35461 aggtcaatac gtgaaatatg cgttccgtat ttatctggtt ctgtaataat tacgccattt
    35521 acaacttctt tttttacaag tttatgcata tgagccgcaa aaatagcgct tagttccgga
    35581 caagcattcg caatatcttg aacaccagta cctgggattc cattctcatt ttctagtccc
    35641 atatgcataa cccctaccat tacatctact ttatcttcta attctttaat agcctttttt
    35701 gtctcttcta ctggattttt cactactaaa ccatccaaat gatctgtccc tttttcaaaa
    35761 tcactaatca ttggtgtatt cataccaata atcccgactt taattccacc tttttcaaca
    35821 atcgtatatg caggaagaaa acgctctcca ttttccttat aaatatttcc tgctaacgtc
    35881 tttcccttgt attgctcact aacttttttc aatgtatcta atccaaagtt gaattcatga
    35941 tttccaaatg cccaggcgtc atatcccatt gtattcattg ctaccatcat tggcgattgt
    36001 ggcttatcgt tgaataattc tactgagttt ccttgaattg tatccccggc atctactaat
    36061 atggtatttg gattttcttg acgtaccttc tttataaccg tataaagctg cgtcaaactt
    36121 ccactcatat ttgctccatc aagcgcataa tcccaaggca taaatctacc atgaatatct
    36181 gcagtaccta acaatgtaat attaacatta gattcctcag ccttagaaat agctggtttg
    36241 actgttactg ctgttacaag aagcataaga ataataaaat tgcatacata gttcttccat
    36301 ttcatttttt gcataataac aatatttctc ccctttttgt actgtcataa agttgcttga
    36361 actttaaaaa tgtaacttat tattcagaga aattcaacta taaaagataa ttttgtagtt
    36421 ggttttgctg tgaaaatata gagaataaaa tgcatatatc ccctaacaga atagtatttt
    36481 atcattttct aataaaatac ttcttcctcc aacgtgtgaa gggcgctaaa ccaacggtag
    36541 atgtatatgt actttcaaaa ttttggacat gcaactcatt ttcggatttt atttctaatt
    36601 ttttccttct atatgaaaat actgagatca cttccaaaaa taataacccc gctcttcatt
    36661 taagacgggg ttacacttat acagcaaatc ggattcagat ttttttcaaa tgttcgtttc
    36721 ctcttcagga gtaaaatctg ctagtttcgt atttttttct gcttattggt tgctttcaac
    36781 taaattcatc ataattttaa tcaggacttg tattttatca ctcgaaccct tgatgctatc
    36841 ccaaatcgct caataaatag ataatgattt ttacttttca actccacaaa gcaattttat
    36901 ctctttaatt tgttctatat gacgctgttc atgcaaatag atcagttcta tccactgatc
    36961 aagaagtaat tctccaagag ctggatgcgt cactgatttt ttcgctaata tagattcatc
    37021 ttctattgta ctcaggaaac gcatcaattc ttttctagag tcgtttaaca aatcaaccat
    37081 ttgctgcact tcaaatggtt ctatacttgg ttcaatcatt tctggggcta taaattttat
    37141 cgatctatct aataaaatag tgtgaatttc tttacgctca tttaagatac tatccatctt
    37201 ttttaatccc gatgaaataa ctgttataac tctctcatct aataaaacta agtgatgaca
    37261 aacttttgct atactccatt tatccttatc tggtttccta ttaaattgag catcacttaa
    37321 caaagtaatt tcctcaaata attgatttct agtttcataa aacgtgtcat ttacaaatgt
    37381 attcatatga attctccttt cgctagaacc tacatactta aattcctacg ctagaaatat
    37441 tctctatgga aaaaagattt tccttcacta ttattccaat ccaatctttt ctttctttag
    37501 taggttctct aattcatgct gaaatgtatg agttctctca acatccttga agatttcctt
    37561 gaggttatta tgcgctacag ctacatcata atactttcaa cggaatcctt tcaatataac
    37621 tacataaaac gttcctaatt atcaatctag cattaaatat atgtaaaaaa tcaacctatt
    37681 cattcatttt taatgcttat gtatgtacat ttgttaattt attagttata ttatgggtat
    37741 tgaatgatta cgaaaagtta ataaatcgct tgtataacac cttatatttt tatatccgtg
    37801 aaaactacaa aatgtataaa attccatttg tcaaatgaat ttaatgcgga aggaggtttg
    37861 tggttacttc atcgggatat aataatcagt tttgaactga taaaaatata ggaggcgaca
    37921 taatgtttcg tacgatttca aatttcatga gagtagctga gataagaaac aaaattcttt
    37981 ttacactagc gatgctaatt gtttttcgaa ttggcacgtt tattccagtt cctcatacta
    38041 acgcagaggt attaaaagta caagatcaag ccaacgtttt aggcatgctg aacgtatttg
    38101 gcggaggagc actgcaacac ttctcaatct ttgctgtagg tatcacacca tatattacag
    38161 cttctatcat tgtacaatta ctacaaatgg acgttgtacc taaatttaca gaatgggcaa
    38221 agcaaggaga aatgggccgt aagaaatcag ctcaatttac tcgctacttt acaatcattc
    38281 tcgcattcat acaatccatt gggatgtctt atggttttaa taatatagca ggtggacaat
    38341 taattacaga tcaaagctgg actacatact tatttattgc gacagtttta actgctggta
    38401 ctgcattttt actttggtta ggtgaacaaa ttaccgctaa tggcgttggt aatggaatct
    38461 caatgattat cttcgcagga cttgttgcgg cgattccgaa tgtcgctaat caaatttatt
    38521 tgcaacaatt ccaaaacgca ggcgatcagt tatttatgca cataataaaa atggttttaa
    38581 ttggactcgt aattttagcg atagttgttg gtgttattta cattcaacaa gctgttcgaa
    38641 aaataccgat tcaatatgca aaagctgttt caggaaacaa tcaatatcaa ggagcaaaaa
    38701 atactcattt acctcttaaa gtaaatagtg caggtgtaat tcctgttatc tttgcttcag
    38761 cctttttaat gacgccgcgt acaattgcgc agctcttccc tgattcaagc gtatctaaat
    38821 ggataattgc gaatcttgat tttgcacatc catttggaat gacactatat gtgggtctta
    38881 tcgttgcctt cacatatttc tacgcgttta ttcaagtaaa tcctgaacaa atggctgaga
    38941 atttgaaaaa gcaaaacgga tatgtcccgg gtattcgccc aggtaaatct acagaacagt
    39001 atgtaacaaa aattttatac cgtttaacat ttatcggtgc gattttctta ggagcaattt
    39061 caatattacc acttgtattt acaaaaatcg ctacattacc accatctgct caaatcggtg
    39121 gtacaagttt actaatcatc gtaggtgttg cattagaaac gatgaagacg ttagaaagtc
    39181 aacttgtgaa gcgtcattat aaaggtttta taaaaaaagt gaattaatta caaaaacaca
    39241 ctaggatata aagacctagt gtgtttttta ttctataaaa ataaaaccct cattttctcg
    39301 cttcatattt ttatctttat tttaattacc ataaaagtag ctcctttctc tcaccttcaa
    39361 tatatccctc ggtggttata aaaagtctca gcatgaattt atctataatt aaatagtctg
    39421 gtacaaaatc ttttaatgtt attacttgct ttctaacaat tcttttgtca ccttttattc
    39481 caaaaacttt agcttctaaa taatcaattt cacctaaaaa taaatctatc ctttgatata
    39541 tagggattcc aaccaatcct ttaacttctg gttatattgt gtaagttgtc tattactatc
    39601 gtataaaaag agattttgaa attcattaac aatgtagttt gtagaaacag gtatcatatt
    39661 tttctttcaa aaaaaacaga gtgccgctca actagctctc tgttttaaac taattatatt
    39721 attgcgtatg taaaatacct tgcaaaacaa cttctaatcc ccagcggaat cgttcttctc
    39781 caccagataa catattttct tttagactta caatcattgg ataccttgct gtatctaaag
    39841 cctcatacga agcacgaatt gggtcaagag tggtaccttt ttctttgcga gctgtttgtt
    39901 catatgcgac cgaagcagca tataacagta aaatatctac tccccatgct gatgctcttg
    39961 cattaactcc accttcatgt aattgacaca aaatctgttc agtaagggct aaagaatttg
    40021 gcccaattgg aattgtcatt aaagctaatt ctgccattcc agaagagtcg aataaaattc
    40081 gaaaatatga atatacaagt gtaaatagtt cttttttcca tggttcattt ttctcatctg
    40141 ttatttcaat tttccctaga ccataatcta atacatacgc tcttaattca tcagcatttt
    40201 ttacgtatac atataaagaa gacggacctg tatctaatac ttttgcaatt ttacgcatac
    40261 taaggccaga aataccttca gactctaata ggtcataagc agtcttaaca atgatttcct
    40321 tacttaacgg ttcttttgct ggtcgtgaac gacgactagt aattgtattc gtttgctctt
    40381 ccatagttct cctttagtaa atatattttt attgttgctc atgaagttga ttcataagat
    40441 tatacatttt catagtagca tcctccgaga aacaaatctc aagattatca tttgacactt
    40501 cagcggattg agaagaataa tcgtacattt tttcttcgta attttcaatt gcctcgttca
    40561 aattatcatg ttttacaata gataatgcaa gttctgccgc atcacgcatc gctagattca
    40621 caccttctcc agcaaatgga gacattaaat gtgcagcatc accaattaaa gtaacaccag
    40681 gattactttt ccaagttagt ccaacaggca acatataaat tcgtctagga aaaatcgcac
    40741 catctgcaca tctaatataa tttttaagtg tttcatccca gtcttcgaaa tattgtagaa
    40801 gttgatgttt tgcttcttct aaatttttaa atggaattcc acaattatca agccattttt
    40861 tatctgttct aaaacttaaa tacacgcgaa tactgtcatc tccatttaat tgcgcaagaa
    40921 ttcctttatg ctccgcaagc gcaaatactt tgccacgtcg attaaatttc gccatctgag
    40981 gatgattttt cgttacattt ttcaaattca attctaccat gctaatacca gtatattgcg
    41041 gtatagaatt tgtgacaagt ggacgaattc gagagaaggc accatctgct gctaccacta
    41101 aatcaacagt gtctacatgt ccattttcaa aatgaagttc atgtatacca ttttctacag
    41161 gaatggcttt tgttaagtta tagccccaat gtatacattg cggatcaaca gaatttaaaa
    41221 gtaactcacg taaagtgcct cgatcaattt ctggacgatc tccgcaatta ggatccgcta
    41281 cttcatctaa atatattttc ccgttcttat cacataaacg aaaatcttct ccctcatatc
    41341 tagcaagttc attaaattgt tctaacaatc ctgcttcttt aagcgcctct tgtccggaat
    41401 catgatgaat atctaatgaa cctccttgtt gccgaatcca tggtgatgtt tctctttcat
    41461 atacgacaca ttttaaacca tgtttctgta atatacgagc taatgttaaa cctcctggtc
    41521 cagcacctat aattgcaata cgtttttctc ctttattttt tctttccatc atttatcaca
    41581 ccttatattt tattgaatta cttgttttat ttataacata acgtacactg ttcgtaaagt
    41641 acatcgttcg ttaattacta agcaaattat gttaaactta atgtgtaaaa ataaaaagca
    41701 tgttacaagt cagtagtaac atgcttttta agttgataaa gtaataaact tttattaact
    41761 taatagtcca atgattccat ttgtattatt tacatttctt tcttcaataa cttcccttgc
    41821 ttaaaataaa cgcccagcgt agaacgattt gctaaaaata caccaatcaa gattaaacaa
    41881 gcaccaattc ccattgcagg atttaatggt tctcctaata caaaataacc tacaataaca
    41941 gcaattaacg gggatacata taaccacgtc gatggaaata ctggatttgt ttttgataaa
    42001 agccagtaat ataaaccgtg tccaccgata gatcctacaa atataagata taaaattggc
    42061 cattgtacat tccaagatgt taatacagct aaattcggct gttccattac aacagataca
    42121 attaatagca aaactcctcc ataaaacatt tgaatgccgt taatgagaaa tggtgatacg
    42181 ttaggtaaat ctgaaagtat ctctttagaa cgaatcgaac ctattccata aaacaactct
    42241 cctactaata taacaaggca tgcaatactc catatgaaag taagttcttg atgcatgcca
    42301 ggtaaagata taaacaaaac tcctgtaagt gctataacta aagcaacaag ttgttctttt
    42361 tgcagttttg ttttgtttcg ccttgattgt aatagcaaaa tcatcattgg ggctgttgca
    42421 gatagaactg cagctaatcc agaagaaata tattgttcag cccagtaaag ggtcgcgaat
    42481 gtcataaatg ttaaacaaaa accagcatat ataatacgtt tcgataataa gtaaggcata
    42541 atatcctttc gctttaattt aaaaataata atgagaataa ggcccgccaa aaagaaacga
    42601 attccagctg aaaataatgg tggtgccccc gcttctattc caatttttat cgttaaaaat
    42661 gtcgttccaa aaataataca tactaaaata taatttaaaa tgaccatttt ccttcctcct
    42721 ttttactctt gaaatgagta tagaggatat ggtgtataac agtgtatccg agcatataac
    42781 agttgaataa aaatatagtt gattgtcaga ctatttttcg ctttaattaa attaaaaaga
    42841 aaaacaggtg attctatgaa gatagtacta cgtaaagaat ccaacatacc atattaccaa
    42901 caaatatata tgcaaattgt tgagagaatt caaagcggga tgctttcgca tggcgattac
    42961 ctcccttctt tacgttctat ggccgatgat ttgcaaatta gtttattaac tgttcgtaaa
    43021 gcttataaac agttagaaac gaaaagttat atacgaattg aacaaggaaa aggtgcctat
    43081 atacataaac gtgtgaacaa agatttcaaa ccaattccat atcaatggca acaaacgaaa
    43141 tccattaatg ttatgcgttc tcaatatgta atgaaccaac atcgtaaata ttttgatttt
    43201 tcacaggctg tcctttatcc acgtttatta ccaaatccgt ttctttcaga tgaaatgcac
    43261 aaattactta ataaggatca aatgatactg gcaacatacg gacctgttca aggtgacaaa
    43321 gaacttagag tggaaataac aaactactta aaagaacacc aacaagtagt tacagatcca
    43381 tctcaattat taattacaag tggtgcccag caaggaattg atttaatcgc ccaaacatta
    43441 ttaaagcctg gagacatagt gttagtagaa agtccgtgtt atggagcggc gcttgatgta
    43501 tttgttaata aaggagttca aattatccct gttagtcttg ataacaacgg cattcgctca
    43561 gatctaatcg atgatatttg tcaaagaaag aatcctgttt tgttatatgt gaatcctact
    43621 tttcagaatc caacgggcac agtaatgagt aaagaaagaa gaatggaact tgtagaacta
    43681 gcagagcttt atcaattttt cattttagag gatgattctt tcggagagat atattttgag
    43741 gattttaaaa ttccccctcc aataaaaagc tttgatacaa atggtcatgt tatatattta
    43801 aaagggttta gtaaaacgtt agcaccaggt cttcgcatcg cggcacttgc agctgaaggt
    43861 cctatctttg aatggttata cgccgtgaag gcttcgatgg atattggtag tcccttattg
    43921 acacaaaaag cactacttcc ttttttacga gcggaacgaa tgaaaaatca tttagaaaaa
    43981 ttacggactg ctttacaaat tagacgcgat ttaacaattg atatattatc tccattaaaa
    44041 gaattagaat tcgaaatacc taatggagga tttaacttat gggttacact ccctcagtca
    44101 atcgatcctt ttacattatt acaaaaagcg aatgaagttg atgtttcttt tttacccggc
    44161 acagcttgtc tgataaacca tgaaactcaa tataatcatt tgcgaattag ttattcaatg
    44221 ttaaatgaaa aagatatgtt gattggatta gaaagattac atgatacaat tgccaagttt
    44281 aaatcaatga tttaaactcc aaaacaacaa ctaacctctt attcacacaa taaaaaacca
    44341 acactttaaa attttattaa aagtcaagat ataagctgaa cctattatta atagtgaatt
    44401 cttatctaat gtcatacatt atatgtataa aaattaaaag gatagaagag cttgaataaa
    44461 ttcgccctat ctatcctctt tttaaacaca aatgactaat catagcggac ttcgctgtca
    44521 acagaacctg tattgctcta ttgctatgtt caaacttctt tttattacta cttgttcaat
    44581 aagaggtgtt ttcttcctgc ataaaattta ttttataggg aattcattat acttattaaa
    44641 acaacaacat gatatagaca aaaccaaaga ataaacataa tggactatag aaccaagtgt
    44701 catatctagc aaactgagaa tgcttaattt ttttgaaaaa tccaacaaac ttaaaatcac
    44761 caattgccct aacaatgaaa actaaagcac agacaatact tccgatttta gataaactat
    44821 ttgcttcgaa cccctgcaaa taacctactt gaacaacaat aatgacacta gctaatagaa
    44881 taagaatggc tacgaataat gttccccata ttctcggagt aaaagcaggc ttatgttctc
    44941 cctcttttac tgggataaca gcagcagaac cccatcgacc tccaaaagcc caataaatat
    45001 gcaaaaaact gataaaccac agaagcccca cagctactac tattaatagt aatttcattt
    45061 attcgccccc aatttcgtaa cttcaaagat aacatacact aacgtatgtt atagtgaaaa
    45121 ttttgtccct tcaggtttta taaccatatt agggacattt attatcgaat aatcaattat
    45181 gcctcagcat aattgcgtcc ggaagcttta cttttttcag tggatgtttg gacatccgct
    45241 gaaagaagtt aaaagctcaa ccattttatc aatatcaaaa ttaagatttg cttcaaacct
    45301 tgtcatccat cctacatacg ttaaataggc aagtctcgct cgatcaattg attcagtttc
    45361 gtctacgccc attttttgat acaattttgc aacacaagaa attctttgtt cttctatatc
    45421 tactaaacgt gttgccacaa caggatcgta tttagcccaa gcataaatac cattctcaat
    45481 ttttttatct cgattaaaac taatctgtaa tagctgttct aaagaggcat cctgttgctc
    45541 catactttga acaatcagct ttgttgcatg tacttcccaa aagtcgagca tagaatctaa
    45601 aagctcttga tggtcacgaa aatagtgata gaagcttcct ttgcttattt ttagcaatcg
    45661 agcaagtgct tcaatgcgaa ctttatgtat accttcatta gctaattgtt gtaatcctac
    45721 ttttatccag tcttctctcg ttaattgcat attatctccc caataaaata cggtagcgta
    45781 tgttttacgt tagattacta ctattctcat tttttgtcaa ttattcattc tgtttatttt
    45841 tatgaactgt aatgttgttg ttaatcgtaa tattgatcgt catcaccctc ggtaaattag
    45901 ataacacgaa agtcccttca ggattactga agggactttt acacgtttgt gaaaagtgcc
    45961 tttatgtaca gtctaaaact attttttcag attgcattgc tctagaagct tttctagcat
    46021 ttccaaagta actggttgtg ccttagtagt tagttgatac ccaatccgtc cattcgtttc
    46081 tacagttgct tgttgtaaat tcttgatttc atgtatacct ttttctctca gatgcataaa
    46141 taattgttgt tctgacattt tcgcgcgtaa taaattcttt tttaagattt ctccgttttc
    46201 tataacaata atgctatttc catttagaaa cttttctact tttcgcgatt tcaattcaaa
    46261 aaaatgaata ataagtaaaa cacccgcaaa aataaacgca gcaaaaatag atgggcctac
    46321 tttcctactt aaaataggtt ctacaataat acgtcctata gaaaccacaa taataatttc
    46381 agctctcgtc atttggctaa cagatttact acctgtcaat tttaaaacaa tgattccagt
    46441 gaggattaaa ataatgcttt caaaaagtat attcattaca gcccaatcct ttaatagtga
    46501 atgttactag tattcccatt aaaggatttt tatgatattt taaagtatcc attcacttta
    46561 cgtgccttat tctttgaagc acctctctcc cagctagtaa tggtaaagca tcaactttct
    46621 tcattgcttc tacttgtgat tcgttacgaa tcattgcata cacagtatga ccttctttta
    46681 ttagcattgg tattaaagaa cgtgctgttg cacctgccac aaaaatttcc atatgtgttt
    46741 cttcttattt tgaatatcat aattgagacg agacatatat aagctatgta caataatcaa
    46801 tatgaaagat tcatctaaaa ttaaagctat aatgttggct agcaaccaat agtgataaca
    46861 tgataattga atttgatgga tatggaatta atgagtatgt tattggtcat aactgttcta
    46921 tcagtaagtt aaaaaaatgt attttaacgt aaaaaatgaa gagttatcta atgaggagct
    46981 tataaattta ttttgtgtac gttatcattt t
//
