LOCUS       NZ_CP035996            28273 bp    DNA     linear   CON 25-JUN-2024
DEFINITION  Bacillus mycoides strain BPN36/2 plasmid p539.
ACCESSION   NZ_CP035996
VERSION     NZ_CP035996.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 538903)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 538903)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 168.724x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739445.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:17:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,019
            CDSs (total)                      :: 5,865
            Genes (coding)                    :: 5,631
            CDSs (with protein)               :: 5,631
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 100 of 234
            Pseudo Genes (incomplete)         :: 149 of 234
            Pseudo Genes (internal stop)      :: 70 of 234
            Pseudo Genes (multiple problems)  :: 74 of 234
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:36:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 510630
            Orig. end                         :: 538903
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035996.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28273
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..28273
                     /SMILES="NC(C(O)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28273
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>28273](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>28273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    complement(647..665)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 27.57"
                     /tool="antismash"
     misc_feature    726..739
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    complement(857..870)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     gene            1360..2067
                     /locus_tag="EXW32_RS29655"
                     /old_locus_tag="EXW32_30350"
     CDS             1360..2067
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092330.1"
                     /locus_tag="EXW32_RS29655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30350"
                     /product="response regulator transcription factor"
                     /protein_id="WP_033729090.1"
                     /transl_table=11
                     /translation="MNTIMIVEDDIKIAELLGTHIKKYGYQSVIIEDFENILATFQKIK
                     PDLVLLDVNLPNFDGYYWCRQIRAISTCPIIFLSARSGEMDQVMALENGGDDYITKPFY
                     YEVVMSKIRSQLRRAYGEYAPKVKERIVEETGLLLFPERMELQLDDKTVLLTKKETILL
                     EILITKSPLLVKREVILEQLWDSSYIDENTLSVNIGRIRKKLQELGIENALETVRGAGY
                     RLHVIWEKEGKDK"
     gene            2064..3050
                     /locus_tag="EXW32_RS29660"
                     /old_locus_tag="EXW32_30355"
     CDS             2064..3050
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016135652.1"
                     /locus_tag="EXW32_RS29660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30355"
                     /product="sensor histidine kinase"
                     /protein_id="WP_078179054.1"
                     /transl_table=11
                     /translation="MKLFLREHIPLICYTFGQLLIILFIYWFDGYPHILTALYSVFLGI
                     FLLIGYLIYRYYSHRSFYKRLSTPMETLNESIQDSDLTPLSMALDKLLQTQYQYYQNQL
                     KKWERKQQEQMIFMNQWVHQMKTPLSVIELITQDAEDPRFDSINEETERIKKGLEMVLY
                     AARLETFEQDFHVDRVPLLEMIDSVIHENKRLFIRSYVYPEVKVGSLLTVETDKKWFRF
                     ILNQVLSNAIKYSSSKKEKVIISAYSKGRAVILEVRDYGVGIPTADLPRVFHPFYTGEN
                     GRKFKESTGMGLYLVKEVCEKLNHKIELESEVGKGTKVRIVFPYASR"
     misc_feature    3101..3118
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            3192..4193
                     /locus_tag="EXW32_RS29665"
                     /old_locus_tag="EXW32_30360"
     CDS             3192..4193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615229.1"
                     /locus_tag="EXW32_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30360"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_215586323.1"
                     /transl_table=11
                     /translation="MIQKQRIEIVDYLRGFALIGITFTNIFQNTSMVSTDAHPYFSSFI
                     YTFMVSKFIYIFMFLLGLSSALLMSNLKKRGERANLIYIRRFSILLLIGVTCTFVGVPA
                     GGLFIMYAIYGLIGFVFQYIPPMINIVVFIAIAILIWFTRDMVLIEGESTNNQIVSLVS
                     MFSGLSMVILGIFLGQVSFFNHLQRCKVLLVTGLVLLFFLTYYSFGWMNNFSSFVLPLF
                     YIVCFTILSMIPMVRSMFSCLIAFGRMSMSNFIVHTSIVFDYLENEKFSFLTYLGIGLS
                     IIVIQIIYSNIWLKYFRMGPLEWIWRMGIYWKKVRIVDQFEKDSNFKENKTC"
     gene            <4189..4290
                     /locus_tag="EXW32_RS30140"
                     /old_locus_tag="EXW32_30365"
                     /pseudo=""
     CDS             <4189..4290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016135652.1"
                     /locus_tag="EXW32_RS30140"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30365"
                     /product="sensor histidine kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VKEVCEKLNHKIELESEVGKGTKVKIVFPYASR"
     misc_feature    4341..4358
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            4434..5204
                     /locus_tag="EXW32_RS29670"
                     /old_locus_tag="EXW32_30370"
     CDS             4434..5204
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016091870.1"
                     /locus_tag="EXW32_RS29670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30370"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_033729084.1"
                     /transl_table=11
                     /translation="MEILHVSDLGKVYPGKISYTALSHIDLKINKGEFVGIMGPSGSGK
                     TTLLNMVSTIDAPTSGEVLIHGENPYLLSPDQLSLFRRRELGFVFQSFNLLNTLTVKEN
                     IVLPLTLDGVSPREMEGKVEAIAEKLGITEILDKRTYEISGGQAQRTAIARATIHNPKL
                     LLADEPTGNLDSKSASDVMELLTTLNKENSTTMMLVTHDAMAASYCDRIVFIKDGQLYN
                     EIYCGDNRKVFYQKILEVLALLGGNAHDFSTIRI"
     gene            5179..7149
                     /locus_tag="EXW32_RS29675"
                     /old_locus_tag="EXW32_30375"
     CDS             5179..7149
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144189.1"
                     /locus_tag="EXW32_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30375"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_033729081.1"
                     /transl_table=11
                     /translation="MTFRQFAFNNVIRSKRTYLAHFLSSTFAIMIFFTYALLAFHPNLQ
                     GDLAASVTINTFAKSGLQISQGLIFFFSFFFILYSVSAFLKTRKKDFGILMLHGMSRSQ
                     LNKLVFIENIIIGIASILTGITIGMAFSKFILIMSNNLLMIDKGLPFYMPFKAIGITFG
                     AFLLLFLFISLFTSRLVNVEQLVELIKAEEKPKPEPKASFWLSLFALICIGLGYTAVFH
                     SVNAIHYKDMKYVLFMMATGVSFVVLGTYFLFTQLSVYVLRVLKKRENIFFKKTNILTI
                     SDLVYQLKDNAKMFFMVTIISAVAFTAVGTCMGLGNSSMAESNSPFAFSYKSYNNNPLE
                     KEHLKKIESELNNGGFKFKPVAYSIKQIPDTLYNSNVLLSVIKISDYNRLAESFDFEKE
                     SLKDQNSSFVIPSKKVANTKSNQNDFQLLHENIKKDMHVDKILTPKELQDTTVTIIIVP
                     DVLYNQMIVNPENQYGQFTINGFIVKNWDQTKKVAEKIVTTLQKDNQGISELEVYNEQY
                     TFSSLIFTWIVMKQGFGLASIMSVLIGIVFFTFAASFLYFRLYTDLERNQQQYKMIAKV
                     GLSKPELKKIVSRQLALLFFLPIAIAITHSTVAFMALQKLANFSVLGSSVVVLICFLVM
                     QIIYFYFVRAQYLKKMYKTIF"
     gene            7173..>7820
                     /locus_tag="EXW32_RS29680"
                     /old_locus_tag="EXW32_30380"
                     /pseudo=""
     CDS             7173..>7820
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006097219.1"
                     /locus_tag="EXW32_RS29680"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EXW32_30380"
                     /product="lipoprotein BA_5634 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKRIGLLIVASISITMLGACSLFGTKDSPANGISIEVGTINEQT
                     RNSIIDSYKDITTSQDLYQLNEGTIDNNKLDIKLPTKFGDSMDTATSNLLFISRTTAEK
                     MNKKGLIRERDNNEGLLSSVPLDSLPKIEKDETIIFANKEYKDLKELTFDEKKMNVQYK
                     GDVWLSPYRGGSKEILLIVDDTLFKEINGKEKTRQILSFNKSFGNLNLVNKGK"
     gene            8228..8599
                     /locus_tag="EXW32_RS29685"
                     /old_locus_tag="EXW32_30385"
     CDS             8228..8599
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665291.1"
                     /locus_tag="EXW32_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30385"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_286675265.1"
                     /transl_table=11
                     /translation="MKETISSYEDLLNMLDSLLREPAQFWDDFYSNREKEIPFFTNKPD
                     ENLVSYFEKKLLNSGKVLELGCGPGRNVIYFAENGCLVDAVDLSKESIHWATERAKEKN
                     VMEAKEKVEKNKYANHAPH"
     gene            9287..9565
                     /locus_tag="EXW32_RS29690"
                     /old_locus_tag="EXW32_30390"
     CDS             9287..9565
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513366.1"
                     /locus_tag="EXW32_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30390"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_033729075.1"
                     /transl_table=11
                     /translation="MKATGVTRKIDELGRVVIPKELRNTLGMKEKSPLEIFVEGEDIVL
                     QRYQPGGVCALTEEVSNRNISLANGKIALSPEGAELLIKEIEQYLVK"
     gene            9814..10137
                     /locus_tag="EXW32_RS29695"
                     /old_locus_tag="EXW32_30395"
     CDS             9814..10137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002069661.1"
                     /locus_tag="EXW32_RS29695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30395"
                     /product="hypothetical protein"
                     /protein_id="WP_033729070.1"
                     /transl_table=11
                     /translation="MKNHKKVNGKILQTNKKWSHLKRKQKEHISNWLRREYTQFLKTHH
                     RKPRKYEHDEILHEVMIQMQEREIWILYGEVKRYYLSEIGKWFRKIESEWESHISNSEK
                     QQV"
     gene            10177..10365
                     /gene="hfq"
                     /locus_tag="EXW32_RS29700"
                     /old_locus_tag="EXW32_30400"
     CDS             10177..10365
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hfq"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016093721.1"
                     /locus_tag="EXW32_RS29700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30400"
                     /product="RNA chaperone Hfq"
                     /protein_id="WP_002203963.1"
                     /transl_table=11
                     /translation="MFNLQEDMYEQLKEKKGEVTVFLKNGVPVRGQILATDKFTVLMMV
                     HGKQQLVYKQAISTIIK"
     misc_feature    10430..10445
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 26.91"
                     /tool="antismash"
     misc_feature    complement(10469..10483)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.53"
                     /tool="antismash"
     misc_feature    10571..10584
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     gene            11175..13421
                     /locus_tag="EXW32_RS29705"
                     /old_locus_tag="EXW32_30405"
     CDS             11175..13421
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016097107.1"
                     /locus_tag="EXW32_RS29705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30405"
                     /product="M60 family metallopeptidase"
                     /protein_id="WP_215586324.1"
                     /transl_table=11
                     /translation="MKRGQKQKTKNLVMITATLSMFATGIMPSLEVFAEEQAQQKKVST
                     TLQNENSVNVENRVFAVPGKGDVSQLQNIERRERNFSAYEPTGLYAKPNEQITIQVQGN
                     QSIQAYIGTFSFDASWREDSKIKSFTLNPGTNTIQSPNGGMIYFYNKQQGGTIQTTVIT
                     GGTATPLFELGKHTKQDLINMLNQYPNAHAVELKGERVLITASPVRVKKYLIDSNTDPV
                     QLLKKMDEATRIQDKISGLSEEQVDKHYLHYVEDNHSLDYYMYAYPHRTAYVGDAIQHV
                     LDINKFTNDGWGPWHEAGHMRQQTPWNFKNMTEVQVNLYSLAVEKAFTSNQPFRLQQEG
                     AYTKAFQYLEQPNKNYDDISDLFVKVVMLWQLQLAYGEDFYPKLHQLYRDMPSNEIPQT
                     DETKKQLFMISASKAAKQNLIPFFEKWGLRPNNDTIQKVAALGYPNLTAEIWKSTDSNP
                     VKPDTPNFSNILEGNQFAWSMKGIGDFEFVKVNLNKSTEEMQINLKAGVPHNYFDSTYA
                     SIKVQNTSGKVIYNKEIYGNKQQNAEQAKVPVKVGNFIEFTHLEGANRATITNMEKNIQ
                     ESFGNKAVYEITKEGLKKVDNIVNPKPDTEAPTQPQGLYASNVTSNSVELKWNSSTDNV
                     GVKEYQVLRDGQLIQTVQGTTFTDQNLTANKEYKYAVKAVDAAGNTSIQSYILPIKTKD
                     QNVSYEKWNPKKAYTKGDKVEHQGKVYEAVQNHQGNGDPNWIFALSLWKPLTIN"
     gene            13562..15544
                     /locus_tag="EXW32_RS29710"
                     /old_locus_tag="EXW32_30410"
     CDS             13562..15544
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002090689.1"
                     /locus_tag="EXW32_RS29710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30410"
                     /product="DUF3472 domain-containing protein"
                     /protein_id="WP_215586325.1"
                     /transl_table=11
                     /translation="MISQKTKKRFNKVIIITAACSMFSMFGTSISHTKAVTRSAAPSVY
                     VSPQNTASSDIISIDWSPVQTAPYTYWAVHNWNAGGEAGGYAGFQQQSGFDENGKRTLH
                     FALWDPIASKEAIKAEYLSPNSQAGLFGGEGTGLKVQTTYGWKDHNWYRMTMRSWQENG
                     HTKFGQWMKDVTKNKWHLIAIMDFPVANVAFNHGLGMFQEDWAGNGQDVREARLKNGYS
                     RKLLDKQWNSWNNQSISGQHDTSYQYDGGATSEYVWVKAGGNTQSTIGTGKIFTLNQPT
                     QPEIGKLDFDIQSIYYENEKLNVSWKLKENSTPQFKGKIEIYNDENMTGQPIEIIDNIK
                     SYQSEISQSILLSTNAYAKIILTDLFDQTVEKKVQIKNESPNILEGNEFAWSLKGIGDF
                     EFAKVNLNKSTEEMQIDLKAGVPHNYFDSTYASIKVKNASGKVVYNKEVYGNKQQNAES
                     KTVPVKVGDFIELTHLEGEERATLINLDNNKHESFDKKVMYEVTKDGLKKVNQIVNPKP
                     DTESPTQPQGLYASNVTSNSVELKWNPSSDNVGVKEYQVLRDGQLIQTVQGTTFTDQNL
                     KVSKEYKYAVKAVDAAGNTSNQSNILLIKTKDQNVSYEKWDPRKAYTKGDKVEHQGKVY
                     EAVQNHQGNGDPNWIFALALWKPLT"
     gene            complement(16850..18019)
                     /locus_tag="EXW32_RS29715"
                     /old_locus_tag="EXW32_30415"
     CDS             complement(16850..18019)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702509.1"
                     /locus_tag="EXW32_RS29715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30415"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_078179272.1"
                     /transl_table=11
                     /translation="MKTRSQITCASLALLIAGSSLLYTTPTSIVKAEPTQNVSSSLQTN
                     TQRDRTSVKQAMRDTLQLGYPGILAKTSEGGKTWGYAAGIANLSTKQSMKTDFRFRIGS
                     VTKTFTATVVLQLAGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQILNHTSGIAEYS
                     RSKDADFMDTKKSYMAEELVKMGISLPPDFAPGKGWSYSNTGYVLLGILIEKVTGNSYA
                     EEIENRIIEPLELSNTFLPGNSSVIPGINHARGYVQPDGTSELKDVTYYNPSVASSAGD
                     MISTADDLNKFFSYLLSGKLLKDQQLKQMLTTVPTGKEGIDGYGLGIYETKLPSGVSIW
                     GHTGGILGFTTLVGGTLGGKHTLVVNWNSLGRTDSPNPFKNILLAEFSK"
     gene            18570..18701
                     /locus_tag="EXW32_RS30430"
                     /old_locus_tag="EXW32_30420"
     CDS             18570..18701
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012974.4"
                     /locus_tag="EXW32_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30420"
                     /product="DnaB-like helicase N-terminal domain-containing
                     protein"
                     /protein_id="WP_003192741.1"
                     /transl_table=11
                     /translation="MSLRKSKQAIDFITITNELQKKNRVEEAGEVSYSTQLVSIVPI"
     gene            18724..19986
                     /locus_tag="EXW32_RS29725"
                     /old_locus_tag="EXW32_30425"
     CDS             18724..19986
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108414.1"
                     /locus_tag="EXW32_RS29725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30425"
                     /product="MFS transporter"
                     /protein_id="WP_059038542.1"
                     /transl_table=11
                     /translation="MKITESKSLWGNTIYLQVFSAYSLLMLGVFIDMLAIMTIVSFEWE
                     VDPTMIGLIPVAYALPGIIFSSWAGVIADRFRKIPIMMFCNLMVGLLTIVLLFVQNIHW
                     LLLALMVRSIFTVFYYPAQQTLTRQIVSPDLLTKAVSINGIVEQGTKILGPLIGGMLLS
                     WFQPEFCLIIRAICCLLAALVLLPTIRLQESLSREHIEKKQQSTWTAWLQGWGYVLSNR
                     MILSTMIFFTIAMAVLQLVDSQFPTLFKSLFPNDKSKMGYIISIIGLGGIIGAFLTQKL
                     KHFQYGWVICGGIALMGIGFGGISLITLISPDASLIFAYLISFIAGIGSGLMFVSNQVI
                     LQIESHQEQVGRVFGIQSSLANAALIISPAMSGPLVHFFGVIELYFYVGIGLIIIAVIG
                     VALQKYLWVTHKQEPVRVNNF"
     gene            20001..24557
                     /locus_tag="EXW32_RS29730"
                     /old_locus_tag="EXW32_30430"
     CDS             20001..24557
                     /NRPS_PKS="Domain: Condensation_Starter (5-299). E-value:
                     1.5e-68. Score: 223.3. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29730_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (457-866). E-value:
                     9.1e-122. Score: 398.5. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29730_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 9.2e-26. Score:
                     81.9. Matches aSDomain: nrpspksdomains_EXW32_RS29730_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1048-1352). E-value:
                     1.6e-144. Score: 474.4. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29730_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1362-1508). E-value: 6.7e-33.
                     Score: 105.7. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29730_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098520.1"
                     /locus_tag="EXW32_RS29730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30430"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_215586326.1"
                     /sec_met_domain="AMP-binding (E-value: 3e-129, bitscore:
                     426.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.8e-13, bitscore:
                     43.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.7e-69, bitscore:
                     227.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANEECYPLSHPQRRIWYTEVIHSGKGICNLRFLFKLHRKMDYSK
                     LNRVVNRVISENDGLCIRLKENGLQEPEQYFIKHEEQEFEFFDFSSVEDSDLLEKWIEQ
                     KTKETFTLFNSDLYYFALIKLNDNECAVFGNVHHIIMDGLSIQIFTSQIAKYYYEMHNE
                     TEEGEIRNSYVQFLANEQTYLNSIRFQKDQKFWLEEFKTIPSVTGLKPYNTYQVSTKAS
                     RETFILSEHLKKKIELFSEDYKLSVYSLFVAAFSLSMYRWTSSLDIALGMAYGNRMTKM
                     ERELIGMMVSTVPLRMDIAPEEEVLSFIGRVSRKQSKSLRHQKFPFDLLLKQINKENNS
                     NVRLFGTTIDYRDRDESGDSLWIPNGEEMQDFAVHIENLTDIDSLQVHIDYRKELFSKE
                     EINRFFKTMLAIIENTFKNPKQKVFEIEIISEEDKRKSLVEFNEPKLDFPYHATIHELF
                     EQQAMIYPNAIAVMYEKERITYRELNERANQLAHYLQKKGIGPDSLVGLCVERSLGMII
                     GILGILKAGGAYVPLDPTYPEQRLQYILEDASIQLVVTQESLKGLKWLPENIKLICLDR
                     DRDEIEQESKTLPISNVNPQHLAYVIYTSGSTGNPKGVMVEHHNVIRLFKSTECWYQFN
                     EKDTWTLFHSYAFDFSVWEIWGALLYGGKLVVVPYWISRSPKDFYQLLVEEEVTVLNQT
                     PSAFRQLIQVCEQEDENKNLQLRYVIFGGEALEPISLLPWFQRYGEKEPQLINMYGITE
                     TTVHVTYYPITLDDVQHASRSNIGKRIPDLEVYILDAYQQPVPIGVDGELYIGGAGLAR
                     GYLNRPELTAERFISHPFSSDSKARLYRTGDLARYLPDGNLDYRGRIDHQVKIRGFRIE
                     IGEIESTLNAYASIKEAVVIVREDQPGDKRLVAYVVGDGNVGAWREYLKAKLPSYMVPS
                     GFVTMEAIPLTANGKVDREALPVPEEKQIKSEAVAPRNSNEQILATIWKHVLGVKKVGI
                     YDNFFEIGGDSILSIQIISQASQVGLKLTPKQMFECPTIAELAQVAIETQGVQAEQGIV
                     TGEVPLTPIQYWFFEQVHSRPEHWNQSMLLRVKERLDVKLLEGAILNLLKHHDALRFRY
                     EQLPNGTWRQRNERTDEHSVLHVVKRNKANEQAWNKVIQEEMNITQTSFNLVTGPLMRV
                     VYFEDTLSGNDRIFWVIHHLVVDGVSWRILLEDLQVVYNQMKQGQGVRLPAKSTSFKEW
                     SERLQAYSDSGVSKEVQDYWNERVEKETMKIPMDYPMQETTEESIDQVTRTLGVEETHA
                     LLQEVPVTHKTRINEVLLAALGQAIVDFTNQQTVSIHLEGHGREEMVEGIDLSRTVGWF
                     TSIYPVHLNFQGTKTPIEGLKAVKDQLRQIPNRGVDYGILRYLKKELLPFYQQKPSISF
                     NYLGQFDQVFSKESLFMQETGFTFLDHAPDSKPSHLIEVIGMVKDEKLHFVWIYSREQF
                     SRLKIQAIADGMLRHLLQLINKPTTESAFTVSDFADAEDLTEESLSKVLLKLTKKRV"
     aSDomain        20016..20897
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29730_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.50E-68"
                     /label="EXW32_RS29730_Condensation_Starter.1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="299"
                     /protein_start="5"
                     /score="223.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="CYPLSHPQRRIWYTEVIHSGKGICNLRFLFKLHRKMDYSKLNRVV
                     NRVISENDGLCIRLKENGLQEPEQYFIKHEEQEFEFFDFSSVEDSDLLEKWIEQKTKET
                     FTLFNSDLYYFALIKLNDNECAVFGNVHHIIMDGLSIQIFTSQIAKYYYEMHNETEEGE
                     IRNSYVQFLANEQTYLNSIRFQKDQKFWLEEFKTIPSVTGLKPYNTYQVSTKASRETFI
                     LSEHLKKKIELFSEDYKLSVYSLFVAAFSLSMYRWTSSLDIALGMAYGNRMTKMERELI
                     GMMVSTVPLRMDI"
     aSModule        20016..24524
                     /complete
                     /domains="nrpspksdomains_EXW32_RS29730_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_EXW32_RS29730_AMP-binding.1"
                     /domains="nrpspksdomains_EXW32_RS29730_PCP.1"
                     /domains="nrpspksdomains_EXW32_RS29730_Epimerization.1"
                     /domains="nrpspksdomains_EXW32_RS29730_TIGR01720.1"
                     /locus_tags="EXW32_RS29730"
                     /monomer_pairings="Thr -> D-Thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20406..20471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0001"
                     /evalue="1.40E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="157"
                     /protein_start="135"
                     /score="24.4"
                     /tool="antismash"
                     /translation="VHHIIMDGLSIQIFTSQIAKYY"
     CDS_motif       20799..20888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0002"
                     /evalue="2.00E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="296"
                     /protein_start="266"
                     /score="29.8"
                     /tool="antismash"
                     /translation="DIALGMAYGNRMTKMERELIGMMVSTVPLR"
     CDS_motif       20937..21053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0003"
                     /evalue="3.40E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="351"
                     /protein_start="312"
                     /score="26.1"
                     /tool="antismash"
                     /translation="SRKQSKSLRHQKFPFDLLLKQINKENNSNVRLFGTTIDY"
     aSDomain        21372..22598
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29730_AMP-binding.1"
                     /evalue="9.10E-122"
                     /label="EXW32_RS29730_AMP-binding.1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="866"
                     /protein_start="457"
                     /score="398.5"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQAMIYPNAIAVMYEKERITYRELNERANQLAHYLQKKGIGPD
                     SLVGLCVERSLGMIIGILGILKAGGAYVPLDPTYPEQRLQYILEDASIQLVVTQESLKG
                     LKWLPENIKLICLDRDRDEIEQESKTLPISNVNPQHLAYVIYTSGSTGNPKGVMVEHHN
                     VIRLFKSTECWYQFNEKDTWTLFHSYAFDFSVWEIWGALLYGGKLVVVPYWISRSPKDF
                     YQLLVEEEVTVLNQTPSAFRQLIQVCEQEDENKNLQLRYVIFGGEALEPISLLPWFQRY
                     GEKEPQLINMYGITETTVHVTYYPITLDDVQHASRSNIGKRIPDLEVYILDAYQQPVPI
                     GVDGELYIGGAGLARGYLNRPELTAERFISHPFSSDSKARLYRTGDLARYLPDGNLDYR
                     GRIDHQVKIR"
     CDS_motif       21558..21599
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0004"
                     /evalue="4.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="533"
                     /protein_start="519"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       21795..21854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0005"
                     /evalue="2.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="618"
                     /protein_start="598"
                     /score="35.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMVEH"
     CDS_motif       22386..22475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0006"
                     /evalue="6.70E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="825"
                     /protein_start="795"
                     /score="59.9"
                     /tool="antismash"
                     /translation="PIGVDGELYIGGAGLARGYLNRPELTAERF"
     CDS_motif       22563..22628
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0007"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="876"
                     /protein_start="854"
                     /score="33.2"
                     /tool="antismash"
                     /translation="YRGRIDHQVKIRGFRIEIGEIE"
     aSDomain        22911..23108
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29730_PCP.1"
                     /evalue="9.20E-26"
                     /label="EXW32_RS29730_PCP.1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="81.9"
                     /tool="antismash"
                     /translation="EQILATIWKHVLGVKKVGIYDNFFEIGGDSILSIQIISQASQVGL
                     KLTPKQMFECPTIAELAQVAI"
     aSDomain        23145..24056
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29730_Epimerization.1"
                     /evalue="1.60E-144"
                     /label="EXW32_RS29730_Epimerization.1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1352"
                     /protein_start="1048"
                     /score="474.4"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="TGEVPLTPIQYWFFEQVHSRPEHWNQSMLLRVKERLDVKLLEGAI
                     LNLLKHHDALRFRYEQLPNGTWRQRNERTDEHSVLHVVKRNKANEQAWNKVIQEEMNIT
                     QTSFNLVTGPLMRVVYFEDTLSGNDRIFWVIHHLVVDGVSWRILLEDLQVVYNQMKQGQ
                     GVRLPAKSTSFKEWSERLQAYSDSGVSKEVQDYWNERVEKETMKIPMDYPMQETTEESI
                     DQVTRTLGVEETHALLQEVPVTHKTRINEVLLAALGQAIVDFTNQQTVSIHLEGHGREE
                     MVEGIDLSRTVGWFTSIYPVHLN"
     CDS_motif       23160..23189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0008"
                     /evalue="1.40E-03"
                     /label="NRPS-E1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1063"
                     /protein_start="1053"
                     /score="11.7"
                     /tool="antismash"
                     /translation="LTPIQYWFFE"
     CDS_motif       23214..23321
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0009"
                     /evalue="5.40E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1107"
                     /protein_start="1071"
                     /score="15.6"
                     /tool="antismash"
                     /translation="WNQSMLLRVKERLDVKLLEGAILNLLKHHDALRFRY"
     CDS_motif       23535..23600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0010"
                     /evalue="2.70E-11"
                     /label="NRPS-E2"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1200"
                     /protein_start="1178"
                     /score="35.6"
                     /tool="antismash"
                     /translation="IFWVIHHLVVDGVSWRILLEDL"
     CDS_motif       24003..24053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0011"
                     /evalue="1.30E-09"
                     /label="NRPS-E5"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1351"
                     /protein_start="1334"
                     /score="29.9"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIYPVHL"
     aSDomain        24087..24524
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29730_TIGR01720.1"
                     /evalue="6.70E-33"
                     /label="EXW32_RS29730_TIGR01720.1"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1508"
                     /protein_start="1362"
                     /score="105.7"
                     /tool="antismash"
                     /translation="LKAVKDQLRQIPNRGVDYGILRYLKKELLPFYQQKPSISFNYLGQ
                     FDQVFSKESLFMQETGFTFLDHAPDSKPSHLIEVIGMVKDEKLHFVWIYSREQFSRLKI
                     QAIADGMLRHLLQLINKPTTESAFTVSDFADAEDLTEESLSK"
     CDS_motif       24096..24158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29730_0012"
                     /evalue="1.60E-11"
                     /label="NRPS-E6"
                     /locus_tag="EXW32_RS29730"
                     /protein_end="1386"
                     /protein_start="1365"
                     /score="36.2"
                     /tool="antismash"
                     /translation="VKDQLRQIPNRGVDYGILRYL"
     gene            24560..>28273
                     /locus_tag="EXW32_RS29735"
                     /old_locus_tag="EXW32_30435"
     CDS             24560..>28273
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-26). E-value: 1.2e-11.
                     Score: 35.7. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29735_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (5-306). E-value:
                     1.3e-115. Score: 377.6. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29735_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (466-870). E-value:
                     1.4e-117. Score: 384.7. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29735_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (974-1042). E-value: 1.3e-24. Score:
                     78.1. Matches aSDomain: nrpspksdomains_EXW32_RS29735_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1061-1237). E-value:
                     7.1e-58. Score: 187.9. Matches aSDomain:
                     nrpspksdomains_EXW32_RS29735_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503051.1"
                     /locus_tag="EXW32_RS29735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_30435"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_215586327.1"
                     /sec_met_domain="Condensation (E-value: 4.9e-69, bitscore:
                     227.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.1e-129, bitscore:
                     424.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-16, bitscore:
                     54.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDVIDIYGLSPLQKGILFHTLYDQDDEHSFSYIVQVGFLLGGQL
                     DVATFEKAWEYVIHRHEVLRSVFVWEEVEKPLQAVYQRLPFTIHQEDWSAHSHEEREKK
                     LHQFLTADRRKGFLLDEAPLMRVTAIKEAEEETRIIWTHHHILLDGWSVSLVFSEVMEV
                     YLKMIKGELLNLPKSLPYKKYIQWINKQDQSQAEEFWTEELKGFYAPTPLAMERKDQEQ
                     EKGYGECVYQISEELTENLQEWVRNSRLTLNTLVQGAWAYLMSRYSGESDIVFGITSSG
                     RPTDLIGAENMVGLFINTLPTRIQLTDDTSVVDWLRKIQMKEMERRQYEHNSLVDIQGW
                     SEVPRNSSLFHTLYVFENYPIQGKRNDDLRLLDVKSAEQTNYPLTLIVMPGKKITLKLM
                     YDRSYFNEKTINRIQGHLLQILIQMTKSLDSKLFEITYLTVEEQTQLLEEWNNTQVKYS
                     AEGMIHTVFEEQVKKNPEAIAAMYENEQITYRELDERANQLAHYLQKRGVGSESLVGVY
                     MERSLQMMIALLGILKSGGAYVPLDPTYPESRLRYILEDAGIEVLVTEENSKNLYISEY
                     VETICMNKDYTAIKKEESIPCISGVTGRSLAYVMYTSGSTGNPKGVMIEHHSVINYLEW
                     MQHKYPLSEKDVVLQKTPFSFDVSVWELFWGIHVGASISFLPRGGEKDPSIIAEVIKKH
                     QVTIVQFVPSMLSVFLDHFNHIELNMNCSSVRHVFSGGEELSSGLVRRFQQKWNYSGQV
                     KLTNFYGPTEATIYVNAFDIQPNQEFVSIGQPIQNTQLYVLDQNQRLQSIGIEGELYIG
                     GAGLARGYLNRPNLTAEKFVSHPFRLGERLYRTGDSVRYLTDGNIEFIGRMDHQVKMRG
                     FRIELGEIEATLEKCSFIKEAVVLVREDRPGDQRLVAYVISDGNTQEWREYLQNQLPNH
                     MIPAHFVELEHFPLTPNGKIDRKALPAPDEQAIGDLNVLPRTPSEELIASVWGQVLGTE
                     NIGIQDSFFESGGHSLLATQIVSRLQELFQIKIPLRELFKHDTVEALAKRVDQLRKEDK
                     KREVPPLVPMTREESIPLSYAQKRLWFIEQLMPNSAMYNIHAACRLTGKWSIEALESGW
                     NQLFERHESLRTIILKQEGEPFQQVQSHVFRHISQTDLTDLSLEDREREMKRLIQNEAE
                     EPFHFGQGPLIRARILKVDREEWVLLCTMHHIISDGWSMGILLEEWMAFYEGALSGKPV
                     ELKELSIQYADFV"
     aSDomain        24566..24637
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29735_NRPS-COM_Nterm.1"
                     /evalue="1.20E-11"
                     /label="EXW32_RS29735_NRPS-COM_Nterm.1"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="26"
                     /protein_start="2"
                     /score="35.7"
                     /tool="antismash"
                     /translation="DVIDIYGLSPLQKGILFHTLYDQD"
     aSDomain        24575..25477
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29735_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.30E-115"
                     /label="EXW32_RS29735_Condensation_DCL.1"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="306"
                     /protein_start="5"
                     /score="377.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="DIYGLSPLQKGILFHTLYDQDDEHSFSYIVQVGFLLGGQLDVATF
                     EKAWEYVIHRHEVLRSVFVWEEVEKPLQAVYQRLPFTIHQEDWSAHSHEEREKKLHQFL
                     TADRRKGFLLDEAPLMRVTAIKEAEEETRIIWTHHHILLDGWSVSLVFSEVMEVYLKMI
                     KGELLNLPKSLPYKKYIQWINKQDQSQAEEFWTEELKGFYAPTPLAMERKDQEQEKGYG
                     ECVYQISEELTENLQEWVRNSRLTLNTLVQGAWAYLMSRYSGESDIVFGITSSGRPTDL
                     IGAENMVGLFINTLPTRIQL"
     aSModule        24575..27685
                     /complete
                     /domains="nrpspksdomains_EXW32_RS29735_Condensation_DCL.1"
                     /domains="nrpspksdomains_EXW32_RS29735_AMP-binding.1"
                     /domains="nrpspksdomains_EXW32_RS29735_PCP.1"
                     /locus_tags="EXW32_RS29735"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       24581..24619
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0001"
                     /evalue="6.20E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="20"
                     /protein_start="7"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YGLSPLQKGILFH"
     CDS_motif       24653..24769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0002"
                     /evalue="3.00E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="70"
                     /protein_start="31"
                     /score="51.7"
                     /tool="antismash"
                     /translation="SYIVQVGFLLGGQLDVATFEKAWEYVIHRHEVLRSVFVW"
     CDS_motif       24986..25051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0003"
                     /evalue="3.60E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="164"
                     /protein_start="142"
                     /score="32.3"
                     /tool="antismash"
                     /translation="HHHILLDGWSVSLVFSEVMEVY"
     CDS_motif       25097..25135
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0004"
                     /evalue="3.60E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="192"
                     /protein_start="179"
                     /score="10.1"
                     /tool="antismash"
                     /translation="PYKKYIQWINKQD"
     CDS_motif       25373..25468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0005"
                     /evalue="6.10E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="303"
                     /protein_start="271"
                     /score="57.2"
                     /tool="antismash"
                     /translation="DIVFGITSSGRPTDLIGAENMVGLFINTLPTR"
     CDS_motif       25517..25639
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0006"
                     /evalue="2.10E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="360"
                     /protein_start="319"
                     /score="62.0"
                     /tool="antismash"
                     /translation="QMKEMERRQYEHNSLVDIQGWSEVPRNSSLFHTLYVFENYP"
     aSDomain        25958..27169
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29735_AMP-binding.1"
                     /evalue="1.40E-117"
                     /label="EXW32_RS29735_AMP-binding.1"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="870"
                     /protein_start="466"
                     /score="384.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKKNPEAIAAMYENEQITYRELDERANQLAHYLQKRGVGSE
                     SLVGVYMERSLQMMIALLGILKSGGAYVPLDPTYPESRLRYILEDAGIEVLVTEENSKN
                     LYISEYVETICMNKDYTAIKKEESIPCISGVTGRSLAYVMYTSGSTGNPKGVMIEHHSV
                     INYLEWMQHKYPLSEKDVVLQKTPFSFDVSVWELFWGIHVGASISFLPRGGEKDPSIIA
                     EVIKKHQVTIVQFVPSMLSVFLDHFNHIELNMNCSSVRHVFSGGEELSSGLVRRFQQKW
                     NYSGQVKLTNFYGPTEATIYVNAFDIQPNQEFVSIGQPIQNTQLYVLDQNQRLQSIGIE
                     GELYIGGAGLARGYLNRPNLTAEKFVSHPFRLGERLYRTGDSVRYLTDGNIEFIGRMDH
                     QVKMR"
     CDS_motif       26144..26185
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0007"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="542"
                     /protein_start="528"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGILKSGGAYVPLD"
     CDS_motif       26378..26437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0008"
                     /evalue="4.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="626"
                     /protein_start="606"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGNPKGVMIEH"
     CDS_motif       26450..26476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0009"
                     /evalue="1.70E+01"
                     /label="C4_DCL_171-183"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="639"
                     /protein_start="630"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="NYLEWMQHK"
     CDS_motif       26966..27052
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0010"
                     /evalue="2.70E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="831"
                     /protein_start="802"
                     /score="51.6"
                     /tool="antismash"
                     /translation="IGIEGELYIGGAGLARGYLNRPNLTAEKF"
     CDS_motif       27134..27199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0011"
                     /evalue="3.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="880"
                     /protein_start="858"
                     /score="38.1"
                     /tool="antismash"
                     /translation="FIGRMDHQVKMRGFRIELGEIE"
     aSDomain        27482..27685
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29735_PCP.1"
                     /evalue="1.30E-24"
                     /label="EXW32_RS29735_PCP.1"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="1042"
                     /protein_start="974"
                     /score="78.1"
                     /tool="antismash"
                     /translation="EELIASVWGQVLGTENIGIQDSFFESGGHSLLATQIVSRLQELFQ
                     IKIPLRELFKHDTVEALAKRVDQ"
     aSDomain        27743..28270
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS29735_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.10E-58"
                     /label="EXW32_RS29735_Condensation_LCL.1"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="1237"
                     /protein_start="1061"
                     /score="187.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ESIPLSYAQKRLWFIEQLMPNSAMYNIHAACRLTGKWSIEALESG
                     WNQLFERHESLRTIILKQEGEPFQQVQSHVFRHISQTDLTDLSLEDREREMKRLIQNEA
                     EEPFHFGQGPLIRARILKVDREEWVLLCTMHHIISDGWSMGILLEEWMAFYEGALSGKP
                     VELKELSIQYADF"
     CDS_motif       27809..27922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0012"
                     /evalue="4.70E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="1121"
                     /protein_start="1083"
                     /score="44.6"
                     /tool="antismash"
                     /translation="AMYNIHAACRLTGKWSIEALESGWNQLFERHESLRTII"
     CDS_motif       28142..28207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EXW32_RS29735_0013"
                     /evalue="2.40E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="EXW32_RS29735"
                     /protein_end="1216"
                     /protein_start="1194"
                     /score="36.0"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGILLEEWMAFY"
ORIGIN
        1 gatatggaga cgttaatgag ctcccttcaa ccaggaaaaa catgtgaaat agctgatgct
       61 tatgtaggaa tgattgataa agtgccagct cgtgtaattg ttcaccgatt aacaaaacaa
      121 cagcaacaaa aacgattaca agatcaagct gtaagagaaa aaaagaaagg aatgaagtat
      181 tctcctcgta gtaaacgact cagtggtatc aatgtatata tgacaaacac ccctacagat
      241 attgtcccga tgggacaggt acatgactgg tattctttac gttggcaaat agagattgta
      301 tttaaaacat ggaaatctct ttttggtatc aatcattgtc acaatattaa gagagatcgg
      361 ctagaatgtc atctttatgg acaattaatc gctatttttc tttgttcttc cactatgttc
      421 aaaatgcgac agctgttact acagaaaaaa caaaaagaat taagtgaata taaagcaatt
      481 tatatgattc aagatcatct gtacttagta tatgaagcta tacaacaaga cacccaagaa
      541 gtatctaaaa ttttccttcg tctgtttgac ctcttacaga aaaactgacg gaaatcgcat
      601 cgatatgaga aaaagacagt ctttgatatt ttaggtgtcg tctatcagtg tactgtatcc
      661 aatctaaagc aaaaaactgc ataatcttta aaaatacacc ttatcaaggt ttatttggta
      721 tgcgtatttt taaaaacaaa taaacaaaat atcaagcatg taggcaacat gaacggaagt
      781 tcataggaaa cccaacctta gcttgatggg catggggtcc cgccaacatt tcacgaattt
      841 cgtacgctaa ggaaattttt atttaaaaaa cttggtttta ccgtacgtta aggaagttct
      901 ataaacgata tttcatgttt gttatggtac tttgtttttg gtaatgagtt ttggaactga
      961 tttttaatcg tatttcattc taatttagta gaaataaata gagctccata aacgacaatt
     1021 ttctggtcac atagtacagt aatatatgtt aattaaaagt cagaaaagta aattggataa
     1081 aaaatattaa tgaatatatt gagttcttat ctattcaaat acccttacta acatcaattc
     1141 attttattaa taaaacttat ctatattctg aaaaatccca acccatttac tgttaaaatt
     1201 tttattaata aaaaacaaca gatataagct ttatttgata ttaattgcat tttagggcgt
     1261 atgtaagata ttatttcttt taaataaatt aacttaaaaa ctaaacataa aaaccaaaca
     1321 aactttaaaa atcacactta aattagagga gagtacgata tgaatacaat catgattgta
     1381 gaagatgata taaaaatcgc tgaattactg ggaactcata ttaaaaaata cggatatcaa
     1441 agtgttatta tagaggattt tgaaaatatc ttagctacat ttcaaaagat taaaccagat
     1501 ttagtgctat tagatgtaaa tctgcctaat tttgacggtt attattggtg ccgccaaata
     1561 cgagctattt ctacttgtcc aattatattt ctatctgcaa ggagtggaga gatggatcag
     1621 gttatggctt tagaaaatgg tggtgatgac tacattacga aaccttttta ttatgaagtt
     1681 gtaatgtcta aaatccgtag tcaactcaga agagcatacg gtgagtatgc tccaaaagta
     1741 aaagaacgaa tagttgagga aacaggatta ctcctgtttc cagaaaggat ggagcttcaa
     1801 ctagatgata agacagtttt gcttaccaaa aaagaaacaa ttttattaga aatattgata
     1861 acaaaatctc cacttcttgt aaaacgcgaa gtaattttag aacaattgtg ggatagttcg
     1921 tatatagatg agaatacatt gagtgtaaat ataggtagaa ttagaaagaa gttacaagaa
     1981 ttaggtatcg aaaatgccct cgaaacagtt cgtggtgcag gatatcgact gcatgttatt
     2041 tgggagaagg aaggaaagga taaatgaaat tattcttacg agaacatatc ccacttattt
     2101 gttatacatt cggccaattg cttattatcc tttttatata ttggtttgat gggtatccac
     2161 atattttgac tgcattatat tcagtatttt tgggcatttt tttattaata ggttatttaa
     2221 tatatcgtta ttatagtcat cgttcattct acaagcgtct atcaacaccg atggaaacgc
     2281 taaatgagtc aatccaggat agcgatttga ctccattatc aatggcccta gataaattat
     2341 tacaaaccca atatcaatat tatcagaacc aattaaaaaa atgggaacga aaacaacaag
     2401 aacaaatgat ttttatgaat caatgggttc atcaaatgaa aacacctctt tctgtcatcg
     2461 aattaattac acaagatgcc gaagatcctc gatttgacag tattaacgaa gaaacagaac
     2521 gaatcaaaaa aggattagag atggtgttat atgctgcccg attggaaaca tttgaacagg
     2581 attttcatgt agatagagta ccattattag aaatgattga ttctgttatt catgaaaata
     2641 agcgtctgtt tatacgtagt tatgtgtatc cagaagtaaa agtgggttcg ctccttactg
     2701 tagaaacaga taagaaatgg tttcgattta tactcaatca agtgctgtca aacgcaataa
     2761 aatattcatc aagtaagaaa gagaaagtaa taatatcagc gtattcaaag ggacgcgcag
     2821 ttattttaga agtaagggat tatggagttg gtattcctac tgctgattta ccacgtgttt
     2881 tccatccatt ttatactgga gaaaatggta ggaaatttaa agagtctacg ggaatgggat
     2941 tatatcttgt taaagaagta tgtgaaaaat taaatcataa gattgagcta gaatctgagg
     3001 taggtaaggg aacgaaagtt agaatcgtat tcccgtatgc ctctcgttaa ccgatgaaag
     3061 aaagattatt catcggtttt ttcttttgaa tcttacaaac ttgttagata aatgttaggg
     3121 aaatcgatag gaaaaatcct atgcaatatg tacattgtat gtagaatcaa aactgaaagg
     3181 agaaaggaat tatgatacaa aagcaacgta ttgaaatagt tgattattta cggggatttg
     3241 cgcttatagg cattactttt acaaatatat ttcaaaatac gagtatggtg agcactgatg
     3301 cccatcctta ttttagctct ttcatttaca ctttcatggt atccaaattt atttatatat
     3361 ttatgttcct tctaggctta tcttctgcat tattaatgtc aaatttaaag aagaggggtg
     3421 aaagggcaaa tttaatatat atccggcgtt ttagtatcct gttattaatt ggtgttacat
     3481 gtacatttgt aggggtccct gccggtggat tatttattat gtatgcaatt tatgggctaa
     3541 taggatttgt atttcagtat ataccaccga tgattaacat tgtcgttttt atcgctattg
     3601 caatattgat ttggttcaca cgtgacatgg ttttaattga aggtgaatca actaataatc
     3661 aaattgtatc tttagtaagc atgtttagcg ggctttcaat ggttatttta gggatatttt
     3721 taggacaggt atcttttttc aatcacctac aaagatgtaa ggtattactt gtaacaggtt
     3781 tagtcctcct attcttttta acatactact cttttggctg gatgaataat tttagttctt
     3841 tcgtactgcc cctattttat attgtttgct ttaccatttt aagtatgatt cccatggtaa
     3901 gaagtatgtt ctcatgttta atcgcatttg gccgaatgtc tatgtcaaac tttattgtgc
     3961 acacatcgat tgtttttgac tatttagaaa atgaaaagtt ctcattctta acctatttag
     4021 gtatcggtct atccattatt gttatacaaa ttatttatag taacatatgg ttaaagtact
     4081 tcagaatggg acctttagaa tggatatggc gtatggggat atattggaag aaagttagaa
     4141 ttgtagatca attcgagaaa gattctaact ttaaagaaaa caaaacctgt taaagaagta
     4201 tgtgaaaaat taaatcataa gattgagcta gaatctgagg taggtaaggg aacaaaagtt
     4261 aaaatcgtat tcccatatgc atctcgttaa ccgatgaaag gtaaactttt catcggtttt
     4321 ttcttttgaa tcttacaaac ttgttagata aatgttaggg aaatcgatat gagacatact
     4381 atatataggc tacacttcat gtatagaaaa gagaaatgga gggtgaaata cttgtggaga
     4441 tactacatgt ttcagattta gggaaagttt atcctgggaa aatttcttat acagcattat
     4501 cccatattga tttaaaaata aacaaaggtg aatttgtagg aattatggga ccatctggga
     4561 gtggtaaaac aacgctatta aatatggttt ctactataga tgctccaaca tcaggagaag
     4621 tattaattca tggagaaaat ccatatctgt tatctccaga tcagttgtct ttatttcgaa
     4681 gacgtgaatt agggtttgtt tttcaatcat ttaatctcct taatacattg acagtgaaag
     4741 aaaatattgt tcttccactt acgcttgatg gtgtaagccc tagagaaatg gaagggaaag
     4801 tggaagctat tgctgaaaaa ctggggataa ctgaaatatt agataaacgt acgtatgaaa
     4861 tttctggtgg gcaggcacaa agaacagcaa tcgcacgagc tactattcat aatccgaaat
     4921 tattacttgc ggatgagcct acaggaaatc tggattcaaa atctgctagt gatgtgatgg
     4981 aattattgac aacgcttaat aaagaaaata gcacaacgat gatgttagtg acacatgatg
     5041 caatggctgc aagttattgt gatcgaattg tgtttatcaa agatggacag ttatacaatg
     5101 agatttattg tggagataat cgcaaagtat tctatcaaaa aattctagag gttttagcat
     5161 tattaggagg aaatgcacat gacttttcga caattcgcat ttaataacgt cattcgaagt
     5221 aaacgaacat atttggctca ttttttaagt agtacgtttg ccattatgat tttctttacg
     5281 tatgcattac ttgcatttca tcctaattta caaggcgatc ttgctgccag tgtaacaatc
     5341 aatacatttg caaaatcagg attacagata tcgcaggggt taatattttt cttctcattc
     5401 ttctttatcc tatattctgt aagtgcattt ttaaaaacaa gaaaaaaaga ttttggaatt
     5461 ctaatgctac atgggatgtc acgttcacag ttgaataaat tagtatttat tgaaaatata
     5521 ataattggaa tcgcttctat tttaacagga attacaattg gaatggcgtt ctctaagttt
     5581 atcttaatta tgagcaacaa tctgctaatg attgataaag gactcccatt ttacatgcca
     5641 tttaaagcaa ttgggataac atttggagca ttcttattac tgtttttatt tatttcactt
     5701 ttcacttctc gactagtaaa tgtagagcaa ttagtagaat tgataaaagc agaagaaaag
     5761 ccaaagcctg aaccaaaagc atccttttgg ctatctttat ttgcgcttat ttgtattgga
     5821 ttaggatata cagctgtttt ccatagtgtt aacgcaattc attacaagga tatgaaatat
     5881 gtattattca tgatggcgac aggggtgagc tttgttgtcc ttggaacgta cttcttattt
     5941 acacagctca gtgtgtatgt gttacgtgta ttaaagaaaa gggaaaatat tttctttaag
     6001 aaaacaaaca tactcaccat ttcagattta gtgtatcaat taaaagataa tgcaaaaatg
     6061 ttttttatgg tcactattat atctgccgtt gccttcactg cagtgggaac ttgtatggga
     6121 ttaggtaact catccatggc tgaatcaaat agtcccttcg cattttctta taagtcttat
     6181 aataataatc ctttagaaaa agagcatcta aaaaaaatag aaagcgaact caataatggt
     6241 gggtttaaat tcaaaccagt agcttattca ataaaacaaa ttccagatac cctttataac
     6301 agtaatgtat tattaagcgt tataaaaata agtgattaca ataggttagc agagtcattt
     6361 gattttgaaa aagaaagctt aaaagatcaa aatagtagtt ttgtcattcc ttcaaaaaaa
     6421 gtcgctaata caaaatctaa tcaaaatgac tttcaattgt tgcatgaaaa tataaaaaaa
     6481 gatatgcatg tagataaaat actaactccg aaagaactac aagatacaac cgtcacgata
     6541 attattgtac cagacgtttt atataatcaa atgattgtaa acccagagaa tcaatatggg
     6601 caatttacta tcaatggttt tattgtgaaa aattgggatc aaacaaaaaa ggttgctgaa
     6661 aaaatcgtga ctactttaca gaaagataat cagggtatta gtgaacttga agtatacaac
     6721 gaacaatata cattttcgtc tttaattttt acatggatag tgatgaaaca aggttttgga
     6781 cttgcatcta tcatgagtgt attaataggt attgttttct ttacttttgc tgcaagcttt
     6841 ttatatttcc gattatatac agacttagaa cgaaatcagc agcaatataa aatgatagca
     6901 aaagttggtt taagtaaacc tgaattaaag aaaattgtgt cacgtcaact tgcattgtta
     6961 ttctttttac caattgcaat agcgattaca catagtacag ttgcttttat ggccttacaa
     7021 aagttagcca atttttcagt cttgggtagt tccgttgtgg tattgatttg tttcttagtt
     7081 atgcaaatta tatactttta ctttgttcgt gctcaatatt tgaaaaaaat gtataaaaca
     7141 atcttttaat ttaaaaagaa ggagaatata ggataaaaaa aagaattgga ttattaatag
     7201 tagctagtat ttcgattacc atgttaggag catgttcatt atttggtaca aaagactctc
     7261 cagcaaatgg aatttcaata gaagtaggaa cgataaacga acaaacaaga aactctataa
     7321 ttgactcata caaagatata acaacctcac aagacctata tcaattaaat gaagggacta
     7381 tagataataa taagcttgac ataaagctac cgactaaatt tggggattct atggatactg
     7441 ctactagtaa tttactattt attagtagaa caactgctga aaaaatgaat aaaaagggac
     7501 ttattcgtga aagggataat aacgaggggc tcctatcttc agtccctctt gattcgttac
     7561 caaaaataga aaaagatgaa actatcatat ttgcaaataa agaatataaa gacttgaaag
     7621 aactaacatt tgatgagaaa aaaatgaatg ttcaatataa aggggatgta tggctatctc
     7681 catatcgtgg tggatccaaa gaaatcctat taattgtaga tgatacatta tttaaagaaa
     7741 taaatgggaa agaaaaaact agacagattc tatcttttaa taaatctttt gggaatctta
     7801 atttagtcaa taaagggaaa gcaccacatc gctatcaagc taagaaaaac aaatacccca
     7861 aaacgaaaat tttgtatttt ttatattagt aaggctcgtt tttatttaat gagaatgcat
     7921 gaatactcta tttgtaatat taccgtaatg attgtaatga ttattccgaa aactaaaaaa
     7981 gaattccgat tctaagggca tttccggttg tttgattgga ttttgagaaa gagtaaggta
     8041 aatcctttta aagccatata acacgaataa tagatacctt tatgcatctt aaattagcat
     8101 aaataagaat acacagagag tttcaactcg tttgaattta aagtgttttt aaccccgatg
     8161 aaacatgaat tattctaatt attggtaaaa ttagaatgta agattcaagt ggaaagaagg
     8221 ggttaatgtg aaagagacaa ttagtagtta tgaagattta ttgaatatgt tagactcatt
     8281 attgcgcgaa ccagctcaat tttgggatga tttttattcc aatcgtgaaa aggagattcc
     8341 ctttttcacc aataaaccgg atgagaactt agttagttat tttgaaaaaa aattacttaa
     8401 ttcaggaaaa gttcttgagc ttggatgtgg tccaggcagg aatgtaattt actttgctga
     8461 aaacggatgc ttagttgatg cagtagattt atcaaaggaa tcaattcact gggcaacaga
     8521 acgagcaaaa gaaaaaaatg taatggaagc aaaagaaaaa gtagagaaaa ataaatatgc
     8581 aaatcatgca cctcattgag cattcacgca acttgagaaa agtttgacgc ttgactgagt
     8641 gtctatccaa tcgacgctgg tacaaactgg gcagttacct atcgatcacc taacgaacgg
     8701 tttgtgtacg catctacctt taaggctctg attgcagggg cattgttact acaatatcca
     8761 attgacaaat taggcgatat tttcacttat acaaaatatg atttagtcaa gtgttcacca
     8821 attacagaga atcaagtgga taccggtatg actcttggag gaaattgcgg agacgaatat
     8881 tcattatagt gataaaactg cggggaacat cttattcgaa aaattagaag tcgattcttt
     8941 tttacatcaa aagaatcgtt ttttacattc ttttcattat gattatgcta acaagaacca
     9001 ttaaattaga cgagtaattc aagaaatcac tattacaaac attagatata gtacaaagag
     9061 gtgaggaaca gctcacaatt cccttacttt aagacttaac gctttctcta cgagctgacg
     9121 aattgtttca tttcaattac ttatcttgtt attgtgccaa aaatcctcta tttattttac
     9181 ttgttctttt gtaaatgcaa ataaattttc atgtatggga aaagcttgtt acaatagtaa
     9241 agaataactt gggtacaatt gataatgaaa tggggaaaga tattagatga aagcaaccgg
     9301 agtaactaga aaaatagatg aattagggcg tgtggtaatt ccaaaggaac ttagaaatac
     9361 gctaggtatg aaagaaaaat caccattaga gatctttgta gaaggtgaag acattgtttt
     9421 acagaggtat cagcctggtg gtgtttgtgc gttaacagaa gaagtgtcaa atcgtaacat
     9481 atcattagca aatggtaaga tagcattaag tccagaaggt gcagaattat taataaaaga
     9541 aatagaacaa taccttgtaa aataagaagc tcctttcaag gggctttttt aggtttaaca
     9601 ttataatttc acgtaccgta ataattaata aaaaataaaa caccacacaa atagtctaca
     9661 tttactttta tgttgaatta atccgctaaa tggatcatgt attgtttatt ttgcatagat
     9721 ttcttgcgaa atatgtccct aaagcagtat ttcaatttaa atgtgatacg atagttatat
     9781 attcgttttg ctagtaaaag gagatgagtt tcgatgaaaa accacaaaaa agtaaatgga
     9841 aaaatccttc aaacaaataa aaaatggtca catctcaagc gaaaacaaaa agaacatatt
     9901 tctaattggt tacgtagaga atatacacag tttttaaaaa cacatcatag aaaacctaga
     9961 aagtatgaac atgatgagat tcttcatgaa gtgatgattc aaatgcagga acgtgaaatt
    10021 tggattcttt atggtgaagt aaaaagatat tatctaagcg aaataggaaa atggtttaga
    10081 aaaatagaaa gtgaatggga atcacatata tccaacagtg aaaagcagca ggtatgagaa
    10141 gaaaagtaaa tacaaacaaa ccagggggcg catttcatgt ttaatttaca agaagatatg
    10201 tatgaacaat tgaaagagaa aaaaggggaa gttactgtat ttttaaagaa tggcgttcca
    10261 gtacgtgggc agatccttgc aacagataaa tttactgtct taatgatggt tcatggtaaa
    10321 caacaactgg tatacaaaca agccatctct acaatcatta agtaatacca taaagtattt
    10381 agctctacct aggcaaattt tacgatctat gcaataccaa tctgttaata tgtacaaatg
    10441 taaacaggat attaggggta ccatatagtg aaaacgagtt ttacaaaagt atgaaagtag
    10501 caaactaata taaacaagtt gtaatattgc catcaactca aaaagaacat gtagtaattt
    10561 ctacatgttc tttttttaat aaaaatgaaa gtaaactttt agccgtttag tttactttca
    10621 aatcatttat ttaattaggt ttatcacaac ttattcattt ccctcaaaaa ttcttataga
    10681 agtatacctt taaagacatt acttatagag tcaaggatta tcatgtttaa agatgtgtta
    10741 tgaaatattt ttaaacgttt attaaacatc tacaaccttt ataaatttct tagcgtacaa
    10801 atttatcgaa atgatatggt gaccccaatt aggattacgt tcttctaaaa gtactggtat
    10861 atccgggttt aggtgattag ttacaactgc ttggaagttt ttgtaccaaa acataatgta
    10921 ttaatatttt gacattttta aagattttaa tacgttttta ataataaacg tattaaaatc
    10981 cttctttttc tcatagattc atttgattat tcttcttatc aagtgaattg aaatatgttc
    11041 attatcttat ataaatgagt atatttatgt taaattgtgt aaatatgtgt caatagataa
    11101 tatgaatata taagtaatag atattactta tatattcata ttataagtat ttggaaatat
    11161 agcggaggga tattatgaaa aggggacaga aacaaaaaac aaaaaattta gtgatgataa
    11221 ctgccacatt atctatgttt gctactggaa taatgccttc attagaagtc tttgcggaag
    11281 aacaagcaca gcaaaagaaa gtatctacaa cgttacagaa tgaaaattct gttaatgtgg
    11341 aaaatcgtgt atttgcagtt ccaggaaaag gagatgtctc ccaacttcaa aatattgaaa
    11401 gaagggaaag aaattttagt gcatacgagc caacagggtt atatgctaag ccaaatgaac
    11461 aaataacaat tcaggtacaa ggaaatcaaa gtatacaagc atatattgga actttctcgt
    11521 tcgatgcttc ttggagggaa gattccaaaa ttaaatcatt tactttaaat ccaggtacaa
    11581 acacaattca atctccaaat ggaggaatga tttattttta taataaacaa caaggtggta
    11641 ccattcaaac aacagtaata acaggtggaa cggctactcc tctctttgaa cttggaaagc
    11701 atacgaaaca agatttaata aatatgctca atcaatatcc aaatgcacat gcggtggaat
    11761 taaaagggga gcgcgtattg attactgcta gcccagttcg tgttaaaaaa tatttgatag
    11821 actctaacac agatcctgta caactcttaa aaaaaatgga tgaggctact agaattcaag
    11881 ataaaatatc tggattatct gaagaacaag tagataaaca ttatctgcat tatgtggagg
    11941 ataaccattc tctggattat tatatgtatg catatcctca cagaactgca tatgtaggag
    12001 atgcaatcca acatgtatta gacattaata aatttacaaa tgatggatgg ggaccttggc
    12061 atgaggcagg acatatgaga caacaaacgc cttggaactt taaaaatatg acagaggtac
    12121 aagtcaatct ttacagcctt gctgtagaaa aagcatttac atctaatcaa ccttttagat
    12181 tgcaacaaga gggcgcttat actaaggcat ttcaatactt agaacaacct aataaaaatt
    12241 atgatgacat tagtgacctt tttgttaaag ttgtaatgct ttggcaatta caactagcgt
    12301 acggagaaga cttctatcct aagttgcatc agctgtatag agacatgcct tcaaatgaga
    12361 ttccacaaac tgatgaaacg aaaaaacaat tatttatgat ttcagcatca aaggcagcaa
    12421 aacaaaattt aattccgttt tttgagaaat ggggattacg cccaaataat gatacaatcc
    12481 aaaaagtagc ggcactaggg tatccaaatt taacggctga aatttggaaa agtacagatt
    12541 ctaatccggt taaaccggat acaccgaatt tttcgaatat tttagaagga aaccagtttg
    12601 catggtcgat gaaagggatt ggtgattttg aatttgtgaa agtaaattta aataaatcaa
    12661 cagaagaaat gcaaattaat ctaaaagcag gtgtaccaca taactacttt gatagtacat
    12721 atgcaagtat taaagtgcaa aacacatcag gtaaagtgat atataacaaa gagatttatg
    12781 gaaataagca acaaaatgct gagcaagcaa aagttccggt aaaagtaggc aattttattg
    12841 aattcacaca tttagaaggt gcgaacagag ctactattac aaatatggaa aaaaacattc
    12901 aggaaagttt tgggaataaa gcggtctatg agattacaaa agagggattg aagaaagtag
    12961 ataacattgt taatccgaaa ccagatacag aagctcccac acagccacaa ggattatatg
    13021 caagtaacgt tacttctaac agtgtagagc taaaatggaa ttcttctaca gataatgtag
    13081 gtgtaaaaga atatcaggta ttacgtgatg gacaactaat tcaaacggta caaggaacga
    13141 cgtttactga tcaaaactta acagctaaca aggaatataa atatgcagtg aaggctgtag
    13201 atgcagctgg aaatacatca attcaaagtt acattcttcc gataaaaaca aaagatcaaa
    13261 atgtatctta tgaaaaatgg aatccgaaga aggcatatac aaagggagac aaagtagaac
    13321 atcaagggaa ggtgtatgag gctgttcaaa atcatcaagg aaatggtgac ccgaattgga
    13381 tatttgcgtt atctttatgg aaaccactta caatcaatta atatgtaaga atcagatgtg
    13441 aatatagaac atcatagatt gggtcagtat tttaaagaat tactggatgt tgcttgaatt
    13501 ttgatagatt tctctactaa gttattattt aaaaataaaa attagaaaag gaagtagatt
    13561 agtgattagt cagaaaacga aaaaaagatt taataaagtt attataatta ccgcagcatg
    13621 tagcatgttt tctatgtttg gaacgtctat ttcgcacact aaagcagtaa cacgttcagc
    13681 tgctccttca gtttatgtga gtccacaaaa tacagcttcc tcagatatta ttagtataga
    13741 ttggtcacca gttcagactg caccttatac gtattgggct gtacacaact ggaatgcagg
    13801 tggtgaagct ggaggatatg ctggttttca acaacaaagt gggtttgatg aaaatggaaa
    13861 acgtacttta cattttgcct tatgggatcc aattgcctct aaagaagcaa taaaggccga
    13921 atacttatct ccgaattcac aagctggact ctttggagga gaaggaacag gactgaaggt
    13981 tcaaacaact tatggttgga aagaccacaa ttggtacaga atgacaatgc gttcatggca
    14041 agaaaatggt catactaaat ttggacaatg gatgaaagat gtaacaaaga ataaatggca
    14101 tctaattgca attatggact ttccggttgc taatgttgca tttaatcatg gattaggaat
    14161 gtttcaagaa gactgggctg gtaatggaca ggatgttcga gaagcacgcc taaaaaatgg
    14221 ttatagtcga aagttattag ataaacaatg gaattcttgg aataatcaaa gtatttctgg
    14281 acagcatgat acttcttatc aatatgatgg aggagcgact tcagaatatg tatgggtcaa
    14341 agcaggaggt aatactcaat ctaccattgg aacaggaaaa atattcacac taaatcaacc
    14401 tactcaacct gaaataggaa aactagattt tgatatacaa tctatatatt atgaaaatga
    14461 aaaattaaat gtatcctgga aactaaaaga aaatagcaca ccacaattta aaggtaaaat
    14521 tgaaatttat aatgatgaaa atatgacagg acaaccaatc gagataattg ataatattaa
    14581 atcttatcaa agtgagatta gtcaatctat actattatct acaaatgctt atgcaaaaat
    14641 tatattaaca gatttatttg atcaaactgt tgagaaaaag gtacaaatca aaaatgaatc
    14701 tccaaacatt ttagaaggta acgaatttgc atggtcgcta aaagggattg gagattttga
    14761 atttgcgaaa gtaaatttaa ataaatcaac agaagaaatg caaattgatt taaaagcagg
    14821 tgtaccacat aactactttg atagtacata tgcaagtatt aaagtgaaaa acgcatcagg
    14881 taaagtagta tataacaaag aggtttatgg gaataaacag caaaatgctg aatcaaaaac
    14941 agtcccagta aaagtgggcg attttattga acttacacac ctagaaggtg aagagagagc
    15001 aacgttaata aatttagata ataataagca cgaaagcttt gataaaaagg taatgtatga
    15061 ggttacaaag gatggcctga agaaagtaaa tcaaattgtt aatcctaagc cagatacaga
    15121 gtctccaaca cagccacaag gattatatgc aagcaatgtt acttctaaca gtgtagagct
    15181 aaaatggaat ccttcttcag ataatgtagg tgtaaaagaa tatcaggtat tacgtgatgg
    15241 acaattgatt caaacggtac aaggaacgac gtttactgat caaaacctaa aagttagtaa
    15301 ggaatataaa tatgcagtga aggctgtaga tgcagctgga aatacatcaa atcaaagtaa
    15361 cattcttctg ataaaaacaa aagatcaaaa tgtatcttat gaaaaatggg atccgaggaa
    15421 ggcatataca aagggggaca aagtagagca tcaagggaaa gtgtatgaag ctgttcaaaa
    15481 tcatcaagga aatggtgacc caaattggat attcgctttg gcattatgga agccactaac
    15541 ataggggtct aatatatatt gaaactacgc caaaatgtta gcttgatggc aattatgggg
    15601 tttccctcat tcccattaag ctaacatttt gaagtgccta caaaacggaa attacagcca
    15661 ataaaataaa gtggttttcc aatgttgggt tccgtgaatg ttacctattg aaaaaatgat
    15721 ttatagtaat aacatagaca tttgacgaaa gggcaacgaa tgcatggttg cccttattat
    15781 tctaaaagtt cctttataat ttcttttata tgcttagtgg gcttatcaac atggtttaaa
    15841 taataatttt cagttatgac aagacctggt cctactattg aacgaagaaa aggtgatatc
    15901 tttcctgtgt aattattaat agttatgcat tcagtatctt cattcattag aatgttatat
    15961 ttacatgtta tttctaatac aggctttcct tcattattta tcatttttcg agaactgatg
    16021 gattcaataa gcgcattact ttgttcgatt taaaaactat ctgtattagc caaatcgtag
    16081 gaaataatga aagctatacc tattgcgtta atcatagatt tcctcctgta gtagttatgc
    16141 ttactaaaat ataataatat atattaaaag taaacaatat gagagcaagt gatgtatggt
    16201 tactcttttt tatacgaaat atgacatacc gtaatggatt atataataac aatttcagac
    16261 ataaagataa ttgagaagca tacacttata tagaacggtt gcaaatataa ttaccgatac
    16321 tctttgcgag agagcactta aggagagtgc tctttttcat tttcacactt taaaagagac
    16381 aagcatatag tataaaacaa gttatatttc atctaatccc ttttttacca aagtactcgt
    16441 ggaaacgggt gctgttatta tgtcaccttt tgataaggac aagtataggt acaaccctgc
    16501 gttgttcctt attcactcat atctaactcc ttatcacatt aagagcatcc ttgtgtaggg
    16561 tgctttttat catgtaataa aacacttttt acaccaaaaa agaaagaaaa cgaaaatttt
    16621 atatccctac agttatttat gaaagttcaa ttcatttttt cattttgggg aacaaccaac
    16681 ttcttaagtt gatgggcatg gggtagcacc gtacatccat caacttaaga agaataaacg
    16741 ccaccaaaac aaaaaaagtc ccaaattttt cttgaaaata aattggggct cttgaaccag
    16801 aaaagtatat ttttaactat gaaaactacg ataaattttt ccttttttcc tacttgctaa
    16861 attcagcaag taaaatattt ttaaaaggat taggactgtc agttctaccc aaactattcc
    16921 aattgacgac caacgtatgc ttgcctccaa gtgtacctcc aacaagagta gtaaacccta
    16981 gaatgccacc tgtgtgtccc catatcgaga caccgcttgg aagcttagtt tcatagattc
    17041 caagaccata tccatcgatt ccttcttttc ctgtaggaac tgtagtaagc atttgtttta
    17101 gttgctggtc tttcagtaat ttgccactga gcaagtaaga gaagaattta tttaagtcgt
    17161 cagcagtaga aatcatatct ccagctgagc tagctacact tgggttataa taagtaacgt
    17221 cttttagctc acttgttccg tctggttgga catatccacg ggcatgattg atgcctggaa
    17281 taacgcttga attgccaggt aggaatgtat tcgataattc aagcggttca ataatccgat
    17341 tttcaatctc ttccgcatag ctgtttccgg ttactttttc aataagaata cccagtaata
    17401 cgtatcctgt gtttgaataa gaccaaccct ttcctggggc aaagtctggg ggcagagaaa
    17461 tccccatctt cactaactct tcagccatat acgatttttt tgtatccata aaatcagcgt
    17521 cttttgacct tgagtattca gcgataccac ttgtatggtt caatatctgc cggatagtaa
    17581 tctggttacc atcatatccg tttccttgaa tgacaccagg caaccatttt tcgatggagt
    17641 cgtctagatt caagcggttc tctccagcta attgaagtac aaccgttgcg gtgaacgtct
    17701 tcgtcacgct gccaatgcga aagcgaaaat ctgttttcat tgattgcttg gtgcttagat
    17761 tcgctatccc agcggcatac ccccacgttt ttccaccctc agaagtttta gcaagtatcc
    17821 ccgggtatcc aagttgcaat gtatcccgca ttgcttgctt gacggaagta cgatctcgtt
    17881 gagtatttgt ttgtaacgaa ctagatacat tctgagtggg ctctgctttt acaattgagg
    17941 ttggtgttgt atataataga gaacttccag ctattaaaag ggccagactt gcacatgtaa
    18001 tttgactacg tgttttcata aggcattcct ctcctctatt catattgtat aggtggttgc
    18061 ttgctgtttc atactaacca cacagctatc atcttcaccg attacaaaag gtcaacattg
    18121 aatttgtaat catcttcata agtattattt tatcaacgcc attctgccct aacaaacggt
    18181 aaatctctct tttttcacat gtttgtaaac cacagaaatt acttcttttc cttgaaacac
    18241 ttttgttact agtttgtttt tcatatataa gtcatatctg ttccgccttt cacgcctcgt
    18301 aatattttta tcctatacaa tgaaactctc tttttcctta cccattcctt acaaatttct
    18361 tacgtttaaa atagattcta tttattaata ttatttaaaa tctgcgatac gatttaatct
    18421 taatttagtt gttttataga aatatttctg gtttttagaa aataataatc ggaatattca
    18481 ttgttttcta tattattttt agaaaataat cccattaata ggagtgttat gatttaattg
    18541 ttagtcaata tctcactttt agagcgttag tgtctttgag aaagtcaaag caagctattg
    18601 atttcattac catcacaaac gaactgcaaa aaaagaatag ggttgaagag gcgggagaag
    18661 tctcttattc cacccaatta gtttctatcg tccctattta gtaaacttaa ggagctcgtt
    18721 tttatgaaaa ttaccgaatc aaaaagtcta tggggaaata caatttattt acaagttttc
    18781 tctgcgtatt cactgcttat gctcggagta tttattgaca tgttagccat tatgaccatt
    18841 gttagttttg aatgggaagt agaccccacc atgattggat taattcctgt tgcgtatgca
    18901 cttcctggga ttatatttag ttcatgggca ggcgtgattg ctgatcgctt tagaaaaatt
    18961 ccaattatga tgttttgtaa tctaatggtt ggtttattaa caattgttct tttatttgtc
    19021 caaaatattc attggctttt gttagcatta atggttcgtt ccattttcac cgttttttac
    19081 tatcctgcac agcaaacact aacacgacag attgtttctc ctgatctgct taccaaagca
    19141 gtaagtatca atgggatagt tgagcaagga accaagatac tgggcccact tataggagga
    19201 atgttactga gctggtttca gccagagttt tgtctgatta taagggcaat atgctgttta
    19261 ctagctgctt tggttctgtt gcccacaata aggttacagg aatctctgtc aagagaacat
    19321 atagaaaaga aacagcaaag tacttggact gcttggttac aaggctgggg ttatgtatta
    19381 tccaatcgga tgatattatc aaccatgatt ttctttacaa tagctatggc agtattacaa
    19441 ttagtagact cacagttccc tactttattt aagagcttgt tcccaaatga taagagtaaa
    19501 atgggataca tcatttctat tattggtctt gggggaataa ttggcgcatt cttaactcag
    19561 aaattaaaac attttcaata tggttgggta atatgtggag gtattgcttt aatgggaatt
    19621 ggctttggag gaataagtct gataactctg ataagtcctg atgcatccct catttttgcc
    19681 tatctgatca gttttatagc tggtattgga agtggactta tgtttgtatc caatcaagtc
    19741 attctacaaa tagaatctca tcaagaacag gtcggaagag tatttgggat tcaaagcagt
    19801 ttagcaaatg cagccctcat tatttctcct gctatgagcg gtccactggt tcactttttc
    19861 ggagtaattg aactctattt ttatgtgggt attgggctca tcatcattgc agtaattggg
    19921 gttgcactac agaaatattt atgggttaca cataaacaag aacctgtaag agtaaataat
    19981 ttttgaaggg aagatttttt atggccaatg aggaatgtta tccgttaagt catccacaga
    20041 ggagaatatg gtatacagaa gttattcatt ccggtaaagg gatatgtaat ttaaggtttt
    20101 tgtttaaact tcatagaaaa atggattatt caaaattaaa tcgagttgtg aatcgtgtta
    20161 ttagtgaaaa tgatggtctt tgcatcagat taaaagaaaa tgggcttcag gaacctgaac
    20221 aatattttat taaacatgaa gaacaagaat ttgagttttt cgatttcagt tccgtggagg
    20281 attcagattt gcttgagaaa tggattgagc agaaaacaaa agaaacgttt acattattta
    20341 attcagattt atactatttc gctttaataa aattaaacga taatgaatgt gcagtctttg
    20401 ggaatgttca tcatattatc atggatggtt tatcaatcca aatatttacc agtcagattg
    20461 caaaatatta ttatgagatg cataacgaga ctgaggaagg cgaaattaga aattcatatg
    20521 ttcaatttct ggccaatgaa caaacatact tgaatagtat tcgctttcaa aaagatcaaa
    20581 aattctggtt agaggaattt aaaacaattc catctgtgac gggattgaag ccttataata
    20641 cgtaccaagt tagtaccaaa gcatcacgtg aaacgtttat attatcggag catttgaaga
    20701 aaaagataga gttattttct gaagattata aattaagtgt atattctctt tttgttgctg
    20761 ctttctcatt gtctatgtat cggtggacct cgtcgcttga tattgcatta ggaatggctt
    20821 atggcaatcg tatgactaaa atggagcggg aattaattgg aatgatggtg agtacagttc
    20881 ctctaagaat ggatatcgcc cctgaagaag aagtgctttc atttattggt cgagtgtcca
    20941 gaaaacaaag taaatcatta cgacatcaga aatttccatt tgatttgtta ttaaagcaga
    21001 ttaataaaga gaacaacagc aatgttagac ttttcggaac tacgattgat tatagagatc
    21061 gtgatgaaag tggtgactca ctttggattc caaatggtga agaaatgcaa gattttgcag
    21121 tacatattga gaatttgact gatatagact ctttacaagt acatattgac tatcgtaaag
    21181 agctattttc taaagaagag ataaaccgct tttttaaaac catgttagca ataatagaaa
    21241 atacatttaa aaacccaaag caaaaagttt ttgagattga aattatttca gaagaagata
    21301 aaagaaaaag tttagtagag ttcaatgaac caaagcttga ctttccatat catgcaacca
    21361 ttcatgaatt gtttgaacag caagcgatga tttatccaaa tgctattgca gttatgtatg
    21421 aaaaggagag gattacctat agagagctaa atgaacgtgc aaatcagtta gcacattatc
    21481 tacagaaaaa aggaatagga cccgattctt tggtgggcct ttgtgttgaa cgttctctgg
    21541 gaatgattat aggcattttg gggattttga aggctggtgg agcttatgtt ccacttgatc
    21601 caacatatcc agagcagcga cttcagtata ttttagaaga tgctagcatt caattagttg
    21661 taacgcaaga aagtttaaaa ggattgaaat ggttaccaga aaatataaaa ttgatttgtc
    21721 ttgatcgtga tcgtgatgag attgagcaag aaagtaagac tttaccgatt tctaatgtaa
    21781 atcctcaaca cctagcttac gtaatctata cttcgggatc aacagggaat ccgaagggcg
    21841 tcatggtaga gcatcacaat gttattcgtt tatttaaatc aacggaatgt tggtatcagt
    21901 ttaatgaaaa agatacttgg acgctttttc attcttatgc atttgatttc tcagtatggg
    21961 aaatttgggg agcattattg tatggtggaa aactggttgt tgttccttac tggattagtc
    22021 gatcgcctaa ggatttctat caactattgg tagaggaaga agtcacggtt ctaaatcaga
    22081 cgccttccgc atttcgacaa ttaatacagg tgtgtgaaca agaagatgag aataaaaact
    22141 tgcagctgcg ttatgtgata tttggtggag aagcgttaga acctattagc ttgttaccat
    22201 ggtttcaaag atatggtgag aaagaaccgc agttaattaa catgtatgga attacagaaa
    22261 ctacagttca tgttacatat tatccgatta ctctagatga tgtgcagcat gcttcaagaa
    22321 gtaatatcgg aaaacgaatt ccagatttag aagtgtatat actagacgcc tatcaacaac
    22381 ctgttcctat aggtgtagat ggtgagcttt atattggcgg ggcagggctt gcacgtgggt
    22441 atttaaatag acctgaatta acagcagagc gctttatatc tcatccattt agtagtgatt
    22501 cgaaagcaag attataccgg acaggagact tagcgaggta tttgccggat gggaatctgg
    22561 attatcgtgg aagaattgat catcaggtta aaatacgtgg tttccgaatt gagattgggg
    22621 agattgagtc tactttaaat gcatatgcat ctataaaaga ggcagttgta attgtaagag
    22681 aagatcaacc gggtgataaa cgattagtag catatgttgt aggagatgga aatgtaggtg
    22741 cgtggagaga gtaccttaaa gcgaaactac cgagctatat ggtcccttcg ggatttgtga
    22801 cgatggaagc tattccactt acagctaacg gtaaagttga tcgtgaggcc ttacctgtgc
    22861 cggaggaaaa gcagattaaa agtgaagctg ttgcccctcg gaatagtaac gaacagatac
    22921 tggctaccat ctggaagcat gtgttaggtg ttaaaaaggt gggaatctat gataatttct
    22981 ttgaaattgg tggtgactcg attctcagta ttcaaatcat atctcaagca agtcaagtgg
    23041 gcttaaaact tactccaaag caaatgtttg aatgcccaac cattgccgag ttggcacaag
    23101 tggctataga aacgcaggga gtgcaagcgg agcagggaat tgtgacagga gaagtgcccc
    23161 ttactccaat tcagtactgg ttcttcgagc aagtacattc acgtccggag cattggaatc
    23221 aatcaatgct tttaagagta aaagagagat tggacgtgaa gttactagaa ggagcgatct
    23281 taaacttact aaaacatcat gatgctttac gtttccggta cgaacagtta ccaaatggaa
    23341 cgtggaggca gagaaatgaa aggactgatg agcattctgt acttcatgtg gtaaaacgga
    23401 acaaagctaa tgaacaagcg tggaataaag taatacaaga agagatgaac attactcaaa
    23461 ctagtttcaa tttagttaca ggtccgttaa tgagagtagt ttactttgag gacaccttgt
    23521 ctggaaatga tcgaatattc tgggtgattc atcatttagt agtagatgga gtatcgtgga
    23581 gaattctatt ggaagattta caggtggtat ataaccagat gaaacaaggt caaggagttc
    23641 gcctacctgc aaaaagtaca tcttttaaag agtggtcgga acgcctgcag gcatacagtg
    23701 attcgggtgt ttcaaaagaa gtacaagatt attggaatga acgggtagaa aaagaaacga
    23761 tgaaaattcc aatggactat ccaatgcaag aaacaacaga agaatcgatt gatcaagtga
    23821 cgaggacttt aggagtagaa gaaacacatg cattgttaca agaagttcca gtgactcata
    23881 agacaaggat aaatgaggta ctattggcgg cattaggaca agctatcgtc gattttacaa
    23941 atcagcaaac ggtttctatt catctagaag gacacgggag agaagagatg gttgaaggta
    24001 ttgatctatc acggacagtg ggctggttca cgagtattta tcctgttcat ctgaattttc
    24061 aaggaactaa aacacctatt gaaggattaa aggctgtaaa agatcaattg cgtcaaattc
    24121 cgaatcgcgg agttgattat ggtattttac gttacttgaa aaaagaatta cttccgtttt
    24181 atcagcaaaa gccttcaata agctttaact atttgggcca atttgatcaa gtgttttcaa
    24241 aagaatcttt gtttatgcaa gagacagggt ttacattttt agatcatgct ccagattcca
    24301 agccatctca tctaattgag gttatcggta tggtaaaaga tgagaagtta cattttgttt
    24361 ggatatatag tagagaacag ttttctagat taaaaattca agcgatagca gatggtatgt
    24421 tgaggcatct tcttcaactt attaataaac caacaacaga gtcagctttt acagtatcag
    24481 attttgctga tgctgaggat cttacggaag aaagtttgag caaagtatta cttaaattaa
    24541 caaagaagag ggtgtaaaga tgggagacgt tatagatata tatggattat cacctttgca
    24601 aaaaggaata ttgtttcata ctttatacga tcaagatgat gaacattctt tttcctacat
    24661 tgtacaagta ggcttcttgc tcggggggca attggatgtt gctacttttg aaaaggcttg
    24721 ggaatatgtt attcatcgac atgaagttct acgctcagta tttgtgtggg aggaagtaga
    24781 aaaacctctg caagcagttt accaacgtct tccttttact attcatcaag aggattggag
    24841 tgcccattcg catgaggaga gggagaagaa attacaccag tttttgactg cagatcgtag
    24901 aaaaggattt ttattggatg aagcaccgtt gatgagagtc actgcgatta aagaagcaga
    24961 agaggaaacg agaatcattt ggacacatca tcatattttg ctagatgggt ggagtgtgtc
    25021 attggtcttt agtgaagtga tggaagttta tctcaagatg ataaagggag aattgttgaa
    25081 tcttcctaaa tctcttcctt ataaaaaata tatccagtgg ataaataaac aagatcaaag
    25141 tcaagcagag gaattttgga cagaagaatt aaaggggttt tatgcaccta cgccattagc
    25201 gatggaaaga aaggatcaag aacaggagaa gggctatgga gagtgtgttt atcagatatc
    25261 tgaggaactc actgagaatt tacaagagtg ggtacgaaat agtcgattaa cattgaatac
    25321 gttagtacaa ggcgcatggg cctatttgat gagtaggtat agcggtgaaa gtgacatcgt
    25381 atttggcata actagctctg gacgtcctac tgatttgata ggagcagaga atatggtagg
    25441 tctatttatt aacacattac ctacgagaat tcaattaacg gatgatacat cagtagtaga
    25501 ttggcttcgt aaaatacaga tgaaagaaat ggaacgaaga caatatgagc ataattcgtt
    25561 ggttgatatt caagggtgga gtgaggttcc gcggaatagt tccttatttc ataccttgta
    25621 tgtgtttgaa aattatccaa ttcaaggtaa gagaaatgat gatttaagat tactagatgt
    25681 taaaagcgcg gaacaaacaa attatccttt aacactcatt gtaatgcccg gtaagaaaat
    25741 tactttaaag ttgatgtatg atcgaagcta ttttaatgaa aaaacaataa atcggattca
    25801 gggtcactta ttgcaaatat taattcagat gacgaagagc ttagattcaa aactctttga
    25861 aattacttat ttaacagtgg aagagcagac acagttacta gaggaatgga ataatactca
    25921 agtaaaatat tcagctgaag gcatgattca tacggtgttt gaggagcaag tcaagaaaaa
    25981 tccagaagca atcgcagcaa tgtacgaaaa tgaacaaatt acctatagag agttggatga
    26041 gcgtgcgaat cagctagcac attatttaca aaagcgtggt gtaggttcag agtctctagt
    26101 cggggtatat atggaacgtt cattacaaat gatgatagcg ttattaggta ttctaaaatc
    26161 aggaggggcg tatgttccac ttgatcctac ttatccagag agtcggcttc gttatatatt
    26221 agaggatgct ggaatcgaag tactagtgac ggaagaaaat tcaaaaaatt tatatatatc
    26281 tgaatatgtt gaaacgattt gtatgaataa agattatact gcaattaaaa aagaagaatc
    26341 aatcccatgt ataagtggtg taacagggag aagtttagcg tatgttatgt atacttcagg
    26401 atctacaggt aatccaaagg gagtgatgat tgagcatcat tcagtaatca attacctaga
    26461 atggatgcaa cataaatatc cactttctga aaaggatgtg gtcttgcaga aaaccccatt
    26521 ctcatttgat gtatctgttt gggagttatt ttggggtatt cacgttggag caagtatatc
    26581 tttcctacct cgaggtggag aaaaagatcc ttctattata gctgaagtga ttaaaaaaca
    26641 tcaggttact atagttcaat ttgtaccttc gatgttatct gttttcttag atcacttcaa
    26701 tcatattgaa ttgaacatga attgttcgtc cgtacgccat gtattttctg gtggagaaga
    26761 actaagttca gggttagtta gacgatttca acagaaatgg aattatagtg gacaagtgaa
    26821 attaaccaac ttttatggac caactgaagc cactatttat gtaaatgcat ttgatattca
    26881 gcctaatcaa gaatttgttt ctattgggca gccaatacag aacacgcaat tatatgtatt
    26941 agaccaaaat caacgcttgc aatcaatagg aattgagggt gagttatata ttggtggtgc
    27001 tggtttagca cgtggatact taaatcgtcc gaatcttact gctgaaaaat tcgtttcgca
    27061 tccatttcga ttgggggaac gactatatcg aacaggagat tcagtaagat atctaactga
    27121 tggaaatata gaatttatag gtagaatgga ccatcaagta aaaatgcgcg gttttaggat
    27181 tgaattagga gaaattgaag cgactttaga aaaatgttcg tttattaaag aggctgtcgt
    27241 attagttaga gaagaccgtc caggtgatca acgattggtt gcatatgtaa taagcgatgg
    27301 aaatacccaa gagtggagag agtatttaca aaaccaatta ccgaatcata tgattccagc
    27361 tcactttgta gagttagaac acttcccgct tactccgaat gggaaaattg accgaaaggc
    27421 cttgccagca cctgatgagc aagctattgg agatttaaat gttctacctc ggacgccatc
    27481 ggaagagctt attgcctcgg tttggggtca agtgttaggg acagaaaata ttggtattca
    27541 ggattccttc tttgaaagtg gtgggcactc actacttgct actcaaatcg tctctcgatt
    27601 gcaagaattg ttccaaatca aaatcccatt acgtgaactt ttcaagcacg atacagtgga
    27661 agcattagcg aaacgagtag atcagttgcg caaagaagat aaaaaacgag aggttccacc
    27721 ccttgtacct atgacacgag aagaatctat tccactttcc tatgcgcaga aacgtctatg
    27781 gtttattgaa caattaatgc caaatagtgc gatgtacaat attcatgcag cgtgtcgctt
    27841 aacaggtaaa tggtcaattg aagcattgga atccggatgg aatcagttgt ttgagcgtca
    27901 tgaatcatta cgaacgataa ttctaaaaca agagggtgaa ccttttcaac aggttcaatc
    27961 tcatgtattc agacatatct ctcaaacgga tctaacagat ctctctttag aagataggga
    28021 aagagaaatg aaacggctca ttcaaaacga agcggaggaa ccatttcatt ttggacaagg
    28081 tcctctaatt cgagcacgaa tattgaaagt ggacagggaa gaatgggttc tcctttgtac
    28141 gatgcatcat attatttcag atggatggtc aatgggaatc ttacttgaag aatggatggc
    28201 tttttatgaa ggagcactaa gcggaaaacc ggtcgaattg aaggagttat ctatccaata
    28261 tgcagacttt gtc
//
