LOCUS       NZ_CP035994            23909 bp    DNA     circular CON 25-JUN-2024
DEFINITION  Bacillus mycoides strain BPN36/2 chromosome, complete genome.
ACCESSION   NZ_CP035994
VERSION     NZ_CP035994.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5347123)
  AUTHORS   Fiedoruk,K., Drewnowska,J.M. and Swiecicka,I.
  TITLE     The dynamics of pangenome and proteome of selected Bacillus cereus
            sensu lato representatives from the primary and anthropologically
            changes environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5347123)
  AUTHORS   Drewnowska,J.M., Fiedoruk,K. and Swiecicka,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Department of Microbiology, University of
            Bialystok, 1J Ciolkowskiego, Bialystok 15-245, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 168.724x
            Sequencing Technology :: Illumina MiSeq and MiniIon Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018739445.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 04:17:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,019
            CDSs (total)                      :: 5,865
            Genes (coding)                    :: 5,631
            CDSs (with protein)               :: 5,631
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 100 of 234
            Pseudo Genes (incomplete)         :: 149 of 234
            Pseudo Genes (internal stop)      :: 70 of 234
            Pseudo Genes (multiple problems)  :: 74 of 234
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:36:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3576349
            Orig. end                         :: 3600258
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035994.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23909
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="10"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23909
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23909
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13909](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13909)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(562..1500)
                     /locus_tag="EXW32_RS18000"
                     /old_locus_tag="EXW32_18430"
     CDS             complement(562..1500)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913375.1"
                     /locus_tag="EXW32_RS18000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18430"
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_215585531.1"
                     /transl_table=11
                     /translation="MLKKVFAMSTTVVLAAGLLSGCGTKESSASKNEDTKKGYVPKTLN
                     VQFVPSQNADTLEAKAKPLEKLLSDKLNIPVKVSISTNYNTIVEAMASKQVDVGFLPPT
                     AYVLAHEKKAANVILQAQRFGVDDETGAPTKDLVDVYKSEFVVKKDSNINSVKDLKGKK
                     IGYQDVTSSAGYVWPAAVLLKEGIDPLKDVKPVTLKGHDQSLIALLNGDVDAAVVFQDA
                     RNIVKKDYLNIFDQTKIVKFTEKIPNDTISVRSDLDAEWSKKLQDAFIEIGKNEEGHKI
                     IKEVYSHEGYVKSDDSKFDIVREYGKKVKTQ"
     misc_feature    1521..1537
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 28.44"
                     /tool="antismash"
     gene            1686..3269
                     /locus_tag="EXW32_RS18005"
                     /old_locus_tag="EXW32_18435"
     CDS             1686..3269
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199635.1"
                     /locus_tag="EXW32_RS18005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18435"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_002128579.1"
                     /transl_table=11
                     /translation="MNQNQIVTLNILLTSDVHGTVYPIHYQDNSKAEIGLAKISTLIKK
                     ERSQNANVLLIDNGDFIQGTPFTYHYATYEKDMENPMSLLANYLEYDIAIIGNHEFNYG
                     MDILNNAVTTANSPYLSANILDKNRKEPYFGKPYIIKHIESNIKIAILGVTTHYIPHWE
                     QAHHIKDLQFEDAFETTKKWVSYIRKHEKPDLLVVAYHGGFERDLQTGVPTEVLTGENQ
                     GYAMCHEIEGIDILLTGHQHREIAHTVINGVTILQTGCNGHSVGKVTVTFEKAEQKWVK
                     KESYSELLPVQGIAADQDVLSLVANYEEKTQNWLDKPIGIIYGDMQISDAMQTRLQDHP
                     FIEFINKIQMDIANVSISCTSLFHNTSPGFPKHVTMRDIVSNYIYPNTLKVIRITGADI
                     KNALELSASYFTLKADGTIIVNPTYIEPKPQHYNYDMWEGISYVLNISKPIGERVESLQ
                     YKGAPLNMNEEYDVVMNNYRASGGGNFFMFQNKPVVKDIPTDMSELIANYILKHKRIEA
                     TKNENWKVIK"
     gene            complement(3310..3549)
                     /locus_tag="EXW32_RS18010"
                     /old_locus_tag="EXW32_18440"
     CDS             complement(3310..3549)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172959.1"
                     /locus_tag="EXW32_RS18010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18440"
                     /product="DUF896 domain-containing protein"
                     /protein_id="WP_002014431.1"
                     /transl_table=11
                     /translation="MPSQELIERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNM
                     LNELKGIKVVNEEGTDVTPAKLKALKKQDNAKLN"
     gene            complement(3595..4251)
                     /locus_tag="EXW32_RS18015"
                     /old_locus_tag="EXW32_18445"
     CDS             complement(3595..4251)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016111193.1"
                     /locus_tag="EXW32_RS18015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18445"
                     /product="recombinase family protein"
                     /protein_id="WP_002128580.1"
                     /transl_table=11
                     /translation="MNAIIYARVSTTKEEQETSLLRQKDELLHLAERYQMDVTKVIEEQ
                     ASGYTIERDGILEVLDTIRDEQVDVLLIQDETRLGRGNAKIALMHCLHKEGIKVYTHTH
                     SGELQLSDSDSMVLNIIGIVEEYQRKIHNLKIKRGMQRAVEKGFRPENNLKNRHLSVGR
                     EKKEVPIEEIVRLRRNELTFEEIAATLRGFGHDVSKATVHRRYVEYTKQLLDKED"
     misc_feature    complement(4312..4325)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.42"
                     /tool="antismash"
     gene            4393..5007
                     /gene="lexA"
                     /locus_tag="EXW32_RS18020"
                     /old_locus_tag="EXW32_18450"
     CDS             4393..5007
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413738.1"
                     /locus_tag="EXW32_RS18020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18450"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_002087894.1"
                     /transl_table=11
                     /translation="MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHG
                     HLSRLEEKGYIRRDPTKPRAIEILGDNRTETQSVIQVPIIGKVTAGLPITAVESVEDHF
                     PLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATV
                     KRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH"
     gene            complement(5111..5914)
                     /locus_tag="EXW32_RS18025"
                     /old_locus_tag="EXW32_18455"
     CDS             complement(5111..5914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016512438.1"
                     /locus_tag="EXW32_RS18025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18455"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_002014437.1"
                     /transl_table=11
                     /translation="MMKKILLVAIACIIIGVIGISQTYEKAVQTAEKGDKEDVIKNETL
                     KNVEVKLDAGDIVVQKSPDSSFYVKQKGDVSKQEIRIAEDGDTLKIIGEIEKGVSFDFS
                     FYNFGFQTPTLTILVPERSYQEIKVNSSAGQIEISNVKSDRVSVETLAGEVDLKHVTAK
                     SVEGSTKAGEVNFKKVIGKVTAKTASGDIDIIDHDSKYDLEVSSTAGDVDITLLEKPQD
                     AVITGQTAAGDVTIFNEDNKNITIGNGSKKISGKTAAGDVTIETR"
     gene            complement(5915..6457)
                     /locus_tag="EXW32_RS18030"
                     /old_locus_tag="EXW32_18460"
     CDS             complement(5915..6457)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031379.1"
                     /locus_tag="EXW32_RS18030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18460"
                     /product="DUF1700 domain-containing protein"
                     /protein_id="WP_002128581.1"
                     /transl_table=11
                     /translation="MSKEQFLKELSSHLRKLPEEERQDILFDYEEHFQFGMEEGKTESE
                     IIKGLGSPKVIAKDLLAMYRFDEMKKDPSTSNVTRAVMAAVGLSLFNFIIVLGPLVAII
                     AFIFSFWVGGIASVVTPFFVIVKVFMGTFIWLDLFVSITFVGVGLLLCIVAYYSTKWFK
                     RLCVRYVVWNFKMIKGE"
     gene            complement(6450..6773)
                     /locus_tag="EXW32_RS18035"
                     /old_locus_tag="EXW32_18465"
     CDS             complement(6450..6773)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016105867.1"
                     /locus_tag="EXW32_RS18035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18465"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_002066545.1"
                     /transl_table=11
                     /translation="MNVQFKKGVLELCVLALVKRKDCYGYELVQQISNKFLISEGSVYP
                     LLRRLTKEGYFQTYLKESTEGPPRKYYQLTEQGEMQLTLLVTEWRDFAKGVQEIIEGVE
                     WDE"
     gene            complement(7001..8800)
                     /locus_tag="EXW32_RS18040"
                     /old_locus_tag="EXW32_18470"
     CDS             complement(7001..8800)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096316.1"
                     /locus_tag="EXW32_RS18040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18470"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002128582.1"
                     /transl_table=11
                     /translation="MNHIIYFMKKLYSSAGKILYVNLFGMVLISLLEGIGIILLIPMIS
                     MAGIINIGEETAFIAPVYRFLQDFPKTTSLISILGIYILIVLGQNLLQRNITLRDARTQ
                     QAFVRELRIETYSMILKAKWSFFLEKRKTNLINILTTELARVSYGVNLILQLLAVILFT
                     FIQVGLAFLLSPQITIFVLVFGLLFLVASRAFIKKARILGGKTSKLAQDYLSGITDHFN
                     GIKDIKSNTLEASRLDWLQSITEKMSNEQMEYMRIRSNSQLFYKVSMAILIAFFILLSV
                     SIFKAQPTQLLLIILIFSRLWPRFMTIQSNLEQLAASIPAFKSLWDLQGECNEAIEMQD
                     IHQQKHIKPICIEQGIECKGIYFRYNKKEHLYALQNINVKIPINSMTAIVGHSGAGKST
                     LIDVLMGLIQPEKGQVLIDGTPLTSENLLSLRRAISYVPQDPFLFNASIRENLLMIEPN
                     ASEEQIWTALDFAAAAEFVRMLPKGLDTLIGDRGVRLSGGERQRLVLARAILRQPSILV
                     LDEATSALDTENEVKIQSAIERLKGTMTIVVIAHRLSTIRNADQVIVLGKGEIVQKGEF
                     NQLAKERKGVFRNLLGSQMEVGS"
     gene            complement(8812..9999)
                     /locus_tag="EXW32_RS18045"
                     /old_locus_tag="EXW32_18475"
     CDS             complement(8812..9999)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002014444.1"
                     /locus_tag="EXW32_RS18045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18475"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_002167807.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.7e-67, bitscore:
                     224.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKDFGLNVEFMSKELKLLFTILKLQDDETLQTYSSEWFTDIDWE
                     VFLEQAMHHRVYPVIYQKLKQVDEERIPSHVVQTLNRKYRNNTFQMLYLSAEMERINKF
                     FNENEIRTMFLKGPVLSQDLYGDISLRTSCDLDVLIPVQKLEKVEKLLLEQGYVKDDYI
                     QTILSDWKWRHHHITFFHPTRRIKLEIHWRLNPGPGKEPGFEELWKRKRKSALTSNSVY
                     MLGKEDLFLFLVSHGARHGWSRLRWLVDIKKIVNQDLNWSEINKLMRKYQMFHLGGQAL
                     ILASQMLGARLDKRMMELVAKKRSKQLAQEALFYFKQMINLHTDPVPEEVLAYHSRHLF
                     SLMSNQQKILFIMSQLYPYPIDAKTLPLPKFLHFLYFPLRPFLCLWRKTKKLALS"
     gene            complement(10001..10474)
                     /locus_tag="EXW32_RS18050"
                     /old_locus_tag="EXW32_18480"
     CDS             complement(10001..10474)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012261438.1"
                     /locus_tag="EXW32_RS18050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18480"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_033713202.1"
                     /sec_met_domain="PF13471 (E-value: 4.6e-23, bitscore: 79.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVKRLRMFLSLNMKTKLLFLEAFIFLGWARVLKNITFSKVAPS
                     LGDYMSETSSTHIQPHGDTLKKVSEAISIMSRYTFWESQCLVKAIAGMKMLEKRHIEST
                     LYLGTAKDSHGELIAHAWLRSGSFYVTGSEGMEKFTVVGSFAKRLSEDTIKGE"
     gene            complement(10511..10819)
                     /locus_tag="EXW32_RS18055"
                     /old_locus_tag="EXW32_18485"
     CDS             complement(10511..10819)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128586.1"
                     /locus_tag="EXW32_RS18055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18485"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_002128586.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.8e-26,
                     bitscore: 88.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-15, bitscore: 54.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVHSRKISLEHNVVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEI
                     GGEIWELIEKPIIINQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQIKDQPNR"
     aSDomain        complement(10532..10780)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EXW32_RS18055_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.00E-28"
                     /identifier="RREFam002.1"
                     /label="EXW32_RS18055"
                     /locus_tag="EXW32_RS18055"
                     /protein_end="96"
                     /protein_start="13"
                     /score="88.7"
                     /tool="antismash"
                     /translation="VVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEIGGEIWELIEKPII
                     INQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQI"
     gene            complement(10782..11753)
                     /locus_tag="EXW32_RS18060"
                     /old_locus_tag="EXW32_18490"
     CDS             complement(10782..11753)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108921.1"
                     /locus_tag="EXW32_RS18060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18490"
                     /product="aldolase"
                     /protein_id="WP_002128587.1"
                     /transl_table=11
                     /translation="MFDSMGNVLYQAFGLKIVSEIPLPELSQLNEKKEMADVQVEITDL
                     SEQWGEYSAEKQKTIVVEDDIVMFHVPQTAIFAIQSGEKITFSPMANAEEDKIRLYILG
                     TCMGALLMQRKILPLHGSVIAIDGKAYALIGDSGAGKSTLASAFLNKGYKLLSDDVVAV
                     SLLNKNTAIVHPSYAQQKLWQESINELGMEVAQFSPLFERETKYAVPVNSQFFPDPLPL
                     AGVIELVKTQGEDIEMTRIEGLARLYKLYRHTFRNSLISKLGLMEWHFETSSNIASGME
                     IFQVSRPASRFTAHELVEVILNTIQKGSMVDGCPLEKNIIRT"
     gene            complement(11831..11956)
                     /locus_tag="EXW32_RS18065"
                     /old_locus_tag="EXW32_18495"
     CDS             complement(11831..11956)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172970.1"
                     /locus_tag="EXW32_RS18065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18495"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_000712621.1"
                     /transl_table=11
                     /translation="MKKEWKQPVLEVLNINMTMAGPGHKYPDAVQPDPDDPVKYS"
     CDS_motif       complement(11897..11956)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKEWKQPVLEVLNINMTMA"
                     /locus_tag="EXW32_RS18065_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(11831..11896)
                     /prepeptide="core"
                     /locus_tag="EXW32_RS18065_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-15.80"
                     /molecular_weight="2264.4"
                     /monoisotopic_mass="2263.0"
                     /core_sequence="GPGHKYPDAVQPDPDDPVKYS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEWKQPVLEVLNINMTMA"
                     /leader_location="[11896:11956](-)"
     gene            complement(11972..13909)
                     /locus_tag="EXW32_RS18070"
                     /old_locus_tag="EXW32_18500"
     CDS             complement(11972..13909)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274520.1"
                     /locus_tag="EXW32_RS18070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18500"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_002128588.1"
                     /sec_met_domain="GATase_7 (E-value: 2.6e-19, bitscore:
                     67.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-22, bitscore:
                     79.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIIHFTNEPVSIEHGREVMSRLYKYPADDIQIWHKENAFL
                     GCHAQWITPESVGEQLPFYNYEKQLAITADAIIDNRDELFEKLQVDYSDRKNMTDSELI
                     LLSYQKWGEAAPKYLVGDFAFMIWDEKKQILFGARDFSGSRTLYFYRGEEKFTFCTIIN
                     PLFSLPYVEKKLNKQWIAEFLAIPVNFESVDPQLTVYKYIEQVPPAHTILVKEGEVKFS
                     RYYTPTVGEMLNLKSNEEYEEAFREVYQSAVKARLRTHHQVGAHLSGGLDSGSVVSFAA
                     SDLRAENKKLHTYSYVPVEGFEDWTHKGRIADERPFIQSTVEHVGNIQDYYLELPERSP
                     LSEIDDWLETMEMPYKFFENTFWLSGVYEKASQNGIGVLLSGQRGNWTVSWGPILDYQA
                     MLLKKLHWIRFYRELHLYSRNIGVKKSRVFEVVRRKAFPFLHQLLFSGKQDANSAIINP
                     EFAREMNVFDRLREQDIDITGTSISNAYDMKREQFEKPYYWSINGTYETKLSLRYALWD
                     RDPTNDLRLIQFCLSVPEEQYVQNGLDRALIRRATKNFLPDKVRLNQRVRGIQGADGVY
                     RMAPFWNEFIEEVEELSVDPVISEFLNVEVIKKAISKICKEPRPEYAFDLDFRILMRSL
                     IFYRFIKKAM"
     gene            complement(14202..15365)
                     /locus_tag="EXW32_RS18075"
                     /old_locus_tag="EXW32_18505"
     CDS             complement(14202..15365)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (42-167). E-value:
                     2.7e-07. Score: 22.0. Matches aSDomain:
                     nrpspksdomains_EXW32_RS18075_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557690.1"
                     /locus_tag="EXW32_RS18075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18505"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_215563588.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.8e-96,
                     bitscore: 320.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.4e-05, bitscore:
                     22.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTVQHKKRIYLSSPHMSGNEQKYIQNAFDTNWIAPLGPNVDGFE
                     RELASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSFTFVASANPIVYLGAEPV
                     FIDSEPETWNMSPQALALALYDANKAGELPKAVILVHLYGQSAKLDEILSLCNQYDVPI
                     IEDAAESLGSTYKGKASGTFGRFGVYSFNGNKIITTSGGGMLVSNDVEALERAKFLATQ
                     AKDPAPHYEHSEIGYNYRMSNILAGIGRGQLEVLEDRVRARRFIYKRYYEALSHMPGFY
                     FMPELENTRSNRWLTTLTIDEKESGITIGKLLRTLAEENIEARPMWKPLHMQSLFKEKK
                     YYPHSKNEDVSHSLFQSGICLPSGSNMLAEDQQRVIQSILKAVEWKN"
     aSDomain        complement(14865..15239)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EXW32_RS18075_Aminotran_1_2.1"
                     /evalue="2.70E-07"
                     /label="EXW32_RS18075_Aminotran_1_2.1"
                     /locus_tag="EXW32_RS18075"
                     /protein_end="167"
                     /protein_start="42"
                     /score="22.0"
                     /tool="antismash"
                     /translation="GFERELASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSF
                     TFVASANPIVYLGAEPVFIDSEPETWNMSPQALALALYDANKAGELPKAVILVHLYGQS
                     AKLDEILSLCNQYDVPIIEDA"
     gene            complement(15396..16091)
                     /locus_tag="EXW32_RS18080"
                     /old_locus_tag="EXW32_18510"
     CDS             complement(15396..16091)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016086741.1"
                     /locus_tag="EXW32_RS18080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18510"
                     /product="HAD family hydrolase"
                     /protein_id="WP_002128593.1"
                     /sec_met_domain="HAD_2 (E-value: 6.6e-24, bitscore: 83.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIKAIVFDMDDTLYKEKDYVVSGFKAVDDWIKEKYKKTGFYNIA
                     IQLFDSGERRFVFNETLEKLNIPYDEKLISNLIEQYRFHKPDIQLLDEADWVLNNLVNT
                     VKIGLISDGYLVAQEKKINALKLKERFHSIILTDELGKEYWKPSQIPYEKISKELQVPH
                     QQCVYIGDNLSKDFITAKKLKWLTIHINREGGIHHNLIVEQAYKAHYTIDNLRRLSDIS
                     VLEHMFLDT"
     gene            complement(16093..17070)
                     /locus_tag="EXW32_RS18085"
                     /old_locus_tag="EXW32_18515"
     CDS             complement(16093..17070)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002165241.1"
                     /locus_tag="EXW32_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18515"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_033729827.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.9e-23, bitscore:
                     80.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGNKMNILFTSSGRRVTLIKKFKEVLKQEGIKGKIFTADLKETA
                     PTIYFSDKHFIVPRVNEEGYINELLKICKSEMINLIIPLIDTELTLMANNSKVFEGIGV
                     KVLVSSMELNKIANNKKYTYNFFASNNIPTPRVYSDEEIGRKEYQFPLLIKPYDGSSSK
                     GVTKIMNEKELEFFKDYIPNAMIQEYVSGEEYTIDVMVDFCGNIKTIVPRLRIETRAGE
                     VSKGITKKDFDIIQAAETVIKALPNPIGCITLQCFKKEDGQITFIEINPRFGGGIPLSI
                     EAGANFPLWTIKMCQGEVFIDKDFNWRENLTMLRYDEAVFMESI"
     gene            complement(17057..17662)
                     /locus_tag="EXW32_RS18090"
                     /old_locus_tag="EXW32_18520"
     CDS             complement(17057..17662)
                     /EC_number="2.7.8.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002070010.1"
                     /locus_tag="EXW32_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18520"
                     /product="sugar transferase"
                     /protein_id="WP_002128595.1"
                     /sec_met_domain="Bac_transf (E-value: 2.4e-69, bitscore:
                     230.7, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLFDIFISLLLLICFFFVILLVAIIVKTQIGSPILFRQQRPGL
                     HGKPFYLYKFRTMTNERDRNGELLQDHARLTKVGKFLRKYSLDELPQLINVLKGQLSLV
                     GPRPLLIEYMPLYSKEQAKRHNVRPGITGWAQVNGRNSISWDEKFKLDVWYVENQSFLL
                     DLKILYLTFSKVLKSEGITNNKHVTMPVFKGGIEHGGE"
     gene            complement(18279..20513)
                     /locus_tag="EXW32_RS18095"
                     /old_locus_tag="EXW32_18525"
     CDS             complement(18279..20513)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269321.1"
                     /locus_tag="EXW32_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18525"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_002128596.1"
                     /transl_table=11
                     /translation="MWRRRDNLGNLNDLDLVSKPPFHNDILTYDSTQLKWIPKSFEATN
                     STSIYVLELDRWDVKNDGTDAINTSKGINNALVWAAQQGYTEVVLPRGIYLIDKQTPIE
                     PPSHLTLNLNGSTLKMETNNLTGYAIISFRRNQVYSRITNGIIQGDRYTHDYSSGGTHE
                     AGYGIELGSFTPPADGGNNTRFVSLDNLDILDCTGDAITLNSTFGQISPFPTALASSFE
                     QGAINTTDGSLVSSTTKIRSNLQIDMTQVAIVKYGYFGLYGNGFGALGSEIKCDYYDVI
                     FYTSNNIFLSSKTNVQFFDEVEVPNGASYAKIVLHQGNVPAPANCLINVRVPSFSQYTY
                     IEKCNLHDCRRQGISVCGAKNVYIRDNDIHHIAGTNPQSGLDIEDGYDLNQYIYIERNN
                     FHDNKNYNIIVVNGKFIYISNNSIMNTISNAYVGLSINGGADRVIVTGNNIRLTKVSLL
                     GDVIFSNNYVYGAQVNVQGVYVNRPINILDNIFSNSKMIIDTPFPYAVKVDSCRFINDA
                     DKLNSLSSLYQWTLEMKNEPQTISNCIFEGQDVLYLNYVPVGTVKSGWIFENIIFNNVK
                     NPTLVAGTYTNCFFKDVTFLGITSTGSTLELKDCKFFSIDRNNTLFTVNNLKAFKMMDC
                     HIEKPNGTVLNIQNVSDEIVLGGNTIKITNDTLQRAIIVLDAAFTGKQVIIQNNIINST
                     NLMQVGIDNRTTSITPLVVIQNNVLNNAKITITGREFLQGNIVNGVIDPN"
     gene            complement(20848..22407)
                     /locus_tag="EXW32_RS18100"
                     /old_locus_tag="EXW32_18530"
     CDS             complement(20848..22407)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222557.1"
                     /locus_tag="EXW32_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18530"
                     /product="hypothetical protein"
                     /protein_id="WP_016120648.1"
                     /sec_met_domain="Polysacc_synt (E-value: 1e-07, bitscore:
                     30.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQNSLKNILFGLSGQIISIGMGFVVRTVFIYTLGIEYLGVDGL
                     FTSILLMFSLANLGFDTAIIYSLYRPLAEKDIYKIQALMNLYQKAYRLIGVVVLLLGLS
                     LLPFLDYLVNADTMIKDINIIYLLFLISSVSSYYFVYKQSIIIADQSNYIISKIHTLFI
                     IISNALQIVLLIIISDYIVVLIVQLTLKVIENVYIANKANKLYPFLKEKNNAKLSKADR
                     REFFENLYSLLLYKISGVVINATDNIIISKFIGIIWVGVYSNYLLILNTLNTLLGYLFY
                     SITASVGNLNVKENAEKKYFIFRVINFFNFWIYGFCTVCLWNLINPFITLWLGEEYVFN
                     KYVLFFILLNFFTSGMQNTTTIFRETTGLFKKGKYRPIIAAIINIVVSIILAKQIGIAG
                     VLLGTVISRLCTYFWYDPYIIFKMIFKKSVKVYFIRYILFVVLVLFSVIATDFIGYIFH
                     INIFMDMVIRSILCLIIPNLIFWMVFKEAEEYRYFLNLTRILIKKIKSKILTRKVSNDN
                     YP"
     gene            complement(22426..23694)
                     /locus_tag="EXW32_RS18105"
                     /old_locus_tag="EXW32_18535"
     CDS             complement(22426..23694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084457.1"
                     /locus_tag="EXW32_RS18105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EXW32_18535"
                     /product="hypothetical protein"
                     /protein_id="WP_002128600.1"
                     /transl_table=11
                     /translation="MNSIILDKIVVRNNRVDYSFSIKGDLQKYFKTSNHMFLEYNYDVS
                     DIPLSILAIPFVANVVPLVWITNSTIVINELDKSFYICLNNIKNAYQNMFPGVKFKGSV
                     DVGEIIDNVYIPEFEAASLFSGGLDALTTFIRIKDKNPLLVTEYGWHENEIEGSKVWEA
                     DKENAINFVKDNGLENIFIQSNYGTFIIAGNIDHDFREKLNDTWWHGLHHGLAIISAAI
                     PIAFKLKIKCIYIASSNSPLYQVTCASDPTVDNEIKYASGTVFHDGYELTRQEKIKVVV
                     DHYSASKEPVNIRVCFKNEENCCKCEKCLRTIMGIIAEGRDPREYGFNIPSNLYQYVKT
                     SLNSEVKFFTNTFIEMYWNLIQVRMKQNCDCITDKNLLNWFLDYDFKAQRRKALLKYRI
                     TKFFPILKRKISAKFSRVGTQNN"
ORIGIN
        1 ttgatacacg ttgctgttgt ccccctgata attcatcagc tcgtgcatat gctttttctg
       61 agatattcac tctattcagc gcctggaatg caagctccac atcctctttc ggaaacagac
      121 ctaacgttgt acgcaatgta gaatgatatc caacccgccc agctaataca ttcttcagta
      181 ccgttgatcg cttcacaagg ttaaagcttt gaaaaatcat accaatatct cggcgcatgc
      241 gtcgtaatcc ttttcctttt gcagcagtaa tagactcccc ttcaataatg atttctcctt
      301 ctgtgatttc atgaaggcga tttaccaatc taagaagtgt tgattttcca gcaccggata
      361 gcccgaccat tacaacaaac tcaccttttt gaattttcaa gtttatatta ttcaatcctt
      421 ttgtaccatt cggatacact ttggaaacat ttcgaaactc tatcacacat cttacctacc
      481 ttctatgtat tatcaataac tgaaaaacgg caaactaact gaaatcacac actttccagt
      541 tagtcgccat ttccatatgt attattgcgt tttcactttc tttccatatt cacgaacgat
      601 atcaaattta ctatcatcag atttaacgta tccttcatgt gagtatactt ctttaatgat
      661 tttgtgccct tcctcattct ttcctatttc aatgaaagca tcctgtaatt tcttgctcca
      721 ctctgcatct aaatcagaac gtacagaaat cgtatcgttt ggaattttct ccgtaaattt
      781 tactattttc gtttgatcga atatattcag ataatctttt tttacaatat tacgagcatc
      841 ttggaataca acagctgcat ctacatcacc atttaaaaga gcaataagtg actgatcatg
      901 accttttaat gtaacaggtt tcacatcttt caacggatcg attccctctt ttaacaatac
      961 agccgcaggc catacataac ccgctgatga tgttacatct tgatagccaa tttttttacc
     1021 ttttaaatct tttacactat taatattaga atctttctta acaacaaact ctgatttata
     1081 aacatctact aaatcctttg tgggagctcc agtttcatca tctaccccaa aacgttgcgc
     1141 ctgtaaaatt acgtttgcag cctttttctc atgcgctaac acatacgctg ttggaggtaa
     1201 aaatcctaca tctacttgct tagatgccat cgcttctaca attgtattgt aattcgttga
     1261 aatactaact tttaccggaa tgtttaattt atcacttaat agcttttcca atggttttgc
     1321 cttcgcctct aacgtatctg cattttgaga aggaacaaat tgaacattta gtgtcttcgg
     1381 tacataacct tttttcgtat cttcattttt acttgcactt gattccttcg ttccacatcc
     1441 acttaataat cccgctgcta gtacaactgt tgtgctcatt gcaaaaactt ttttcaacat
     1501 gttaatgcct ccatttttcg ttgttataaa ataaccttcc ataaacatga agaaatatat
     1561 cacatatttt tacaaataat ttcttattta cagaatcttt acatattcta tacattcaca
     1621 ttaaaattct tttcatatat ttgatatgat taattgaaag ataactatag aaaaggtgaa
     1681 tggcgttgaa tcaaaatcaa attgtaactt taaatatttt attaacaagc gatgtacatg
     1741 gtactgtgta tccaattcac taccaagata actccaaagc agaaattggt ttagctaaaa
     1801 tttctactct cataaaaaaa gaacgttctc aaaatgcaaa cgttcttctg attgataacg
     1861 gggacttcat tcaaggaaca ccatttactt atcattacgc tacatacgaa aaagatatgg
     1921 aaaacccaat gtccttatta gccaactact tagagtatga cattgcaatt atcggaaatc
     1981 atgaatttaa ttacggaatg gatatattaa ataatgctgt gactactgca aattcccctt
     2041 atctatcagc aaacatttta gataaaaaca gaaaagaacc ttatttcgga aaaccatata
     2101 taataaaaca tattgaatca aatataaaaa ttgctatttt aggggtgaca acgcattaca
     2161 tcccccattg ggaacaagca catcatatta aagatttaca atttgaagat gcatttgaaa
     2221 caacaaaaaa atgggtttct tacatccgta aacatgaaaa accagattta ctagtcgtag
     2281 cctatcacgg gggatttgaa cgtgatttac aaaccggagt accgactgaa gttttaacag
     2341 gtgaaaacca aggatatgca atgtgccatg aaattgaagg catagatatt ttactaacag
     2401 gccaccaaca ccgagaaatc gctcacaccg tgattaatgg tgtaacaatt ttacagaccg
     2461 gatgcaatgg acactcagtt ggaaaagtaa cagtaacatt cgaaaaagca gaacaaaaat
     2521 gggtgaaaaa agagagttat tcagagttat tgcccgtaca aggaattgcg gcagaccaag
     2581 atgttctttc cttggttgcc aattatgaag agaaaacaca aaattggctt gataaaccta
     2641 ttggaataat ttatggggat atgcaaattt ccgatgctat gcaaacacgt ttgcaagacc
     2701 atccttttat tgaattcata aataaaatac agatggatat agctaatgtt tcaatttctt
     2761 gtacaagttt gtttcataat acatctccag gtttccctaa acatgtaaca atgcgtgaca
     2821 tcgtttctaa ttatatttat ccaaatacat taaaagtaat tagaataacc ggagcggata
     2881 taaaaaatgc tctcgaactc tctgcttctt atttcacatt aaaagcagat ggaaccatca
     2941 tcgtaaaccc tacctatata gaaccaaaac cacaacacta taattacgat atgtgggaag
     3001 ggatttcgta tgtattaaac atttcaaaac caattggaga gagagtagag tctttgcagt
     3061 ataaaggcgc tcctcttaat atgaatgaag aatatgacgt tgttatgaat aattatcgtg
     3121 caagcggtgg cgggaacttc tttatgtttc aaaataaacc agtagtaaaa gacataccaa
     3181 cagatatgtc tgaacttatc gctaactata tattgaagca taaaaggata gaagcaacga
     3241 aaaatgaaaa ctggaaagtt attaaataac aattttaaca aataaaaaaa gatgggctat
     3301 gcccatcttt taatttaatt ttgcattatc ctgctttttt aaagctttta atttcgccgg
     3361 tgtaacgtcc gtgccttctt cgttaacgac tttaattcct tttaattcgt ttaacatatt
     3421 ttgacgaaat ccttttaaat attgttcacg aagcgattgg cgctcacgtt gttcttcttc
     3481 agttaagcct tcagcttttg cttttttcgc taagaagtta atgcgttcaa tgagttcttg
     3541 acttggcatc tcgaatcccc cttctactca aaactgatta ttatcataca atagttagtc
     3601 ctctttatca agcaattgct ttgtatattc tacatacctt cgatgtacag ttgcttttga
     3661 aacatcatga ccaaaaccac gaagtgttgc tgcaatttct tcaaaagtta attcattccg
     3721 gcgcaaacgt acaatttcct caattggcac ttcttttttc tcacgtccta cgcttaaatg
     3781 acgatttttc aaattatttt ctggacgaaa tcctttctcc actgctcttt gcatgccacg
     3841 tttaattttt aaattgtgga tctttctttg atactcttca acgatcccaa ttatatttag
     3901 caccatcgaa tcagaatctg aaagctgtaa ttcaccacta tgtgtgtgtg tataaacttt
     3961 tatcccctct ttatgtaaac aatgcattaa tgcaatcttt gcatttcctc taccaagacg
     4021 cgtttcatct tgtataagta gtacatcaac ttgttcatct cgaattgtat ctagcacttc
     4081 taatatgcca tcacgttcaa ttgtataacc gctagcctgc tcctcaatta cctttgtaac
     4141 atccatttga tagcgctcag ctaaatgcaa taattcatct ttttgacgca ataatgatgt
     4201 ttcctgttct tcttttgttg tgctcacacg tgcataaata attgcattca ttttgaaccc
     4261 ttctttctca ctatattttc cttatagtgt atcataaatt tgcctttcgt tcgaacttat
     4321 gtttgtagaa tgttttttcg catgttatac ttaataataa gaaaaatgaa agaaaacgag
     4381 gtgttagaaa acatggaaaa gttaacgaaa cgccagcaag acattctcga ctttattaag
     4441 ctaaaagtac aagaaaaagg atatccacct tccgtacgtg aaatcggtca agcagtcggc
     4501 cttgcttcta gttctacagt gcacggacat ttatcacgac tagaagaaaa gggatatatt
     4561 cgacgcgatc cgacaaaacc acgcgcaatt gaaattttag gtgacaaccg aacggaaaca
     4621 caatctgtta ttcaagttcc aatcatcgga aaagttactg ccggtttacc gattacagca
     4681 gtcgaaagtg tagaagatca cttcccactt ccagctagta tcgttgctgg agcagatcaa
     4741 gtgtttatgt tacgcatttc tggagatagc atgattgaag ccggtatctt tgatggtgat
     4801 ttagttgttg ttcgccaaca acagtctgca tacaacggtg aaattgtagt tgctttaaca
     4861 gaagataacg aagcaactgt taaacgtttc tataaagaaa aagatcattt ccgtctacaa
     4921 ccggaaaact cttcactaga acctattatt ttaaaacaag tgtcagttat tggaaaagta
     4981 attggcgtat atcgtgattt acattaaaaa taataaaaag aagataattc ccttatttat
     5041 ataggtaatt atcttctttt tatattttga tagatttccg ttcattcaaa agaatgcgtt
     5101 tcattaatta ttaacgcgtt tcaatagtaa catctccagc agcggtttta ccgctaatct
     5161 ttttactacc attaccaatc gttatatttt tattgtcttc attaaaaatt gtcacgtctc
     5221 cagcagcagt ttgcccagtt ataactgcat cttgtggttt ttccaataaa gtaatatcta
     5281 catctccagc agttgaactt acctctaaat catatttaga atcatgatca ataatatcta
     5341 tatccccact agccgttttt gctgttactt tccctattac ttttttaaaa ttcacctcac
     5401 cagcttttgt agacccctcc acactctttg ctgttacatg tttcaaatcc acttctccgg
     5461 cgagtgtttc aacacttacg cggtcacttt tcacattact tatttctatt tgtccagcgg
     5521 atgaatttac ttttatctct tgataagaac gttcaggtac taatatagtc aatgtaggcg
     5581 tttgaaatcc gaaattgtaa aatgaaaaat caaatgaaac acctttttct atttccccta
     5641 tgatttttaa tgtatcacca tcttcagcaa tacgaatctc ctgtttactt acgtctcctt
     5701 tttgctttac ataaaaagag gaatcaggag atttttggac aacaatatct ccagcatcta
     5761 acttaacttc tacatttttt agcgtttcgt ttttaattac gtcctcttta tctcctttct
     5821 ctgcagtttg tactgctttt tcatatgttt gtgaaatccc tattactcca ataatgatac
     5881 aagcgatagc tactaataat atctttttca tcatctactc cccttttatc attttgaagt
     5941 tccagactac atagcgtaca cataatcttt taaaccactt cgtactataa taagctacaa
     6001 tacataacaa caaacctact ccgacaaacg ttatactaac gaaaagatcc aaccatataa
     6061 aagtgcccat aaatactttt acaataacga aaaatggtgt cactacacta gcaatcccac
     6121 cgacccaaaa ggaaaatata aaagctataa ttgcaactaa cgggcctaac acaataataa
     6181 aattaaacaa actaagtcca accgctgcca tgacagctct tgtcacattt gaagtcgacg
     6241 gatctttttt catttcatca aatcgataca tcgcaagtaa gtctttcgca attactttcg
     6301 gagagccaag tccctttatt atttctgatt cagttttccc ctcttccatc ccaaactgaa
     6361 agtgctcttc ataatcaaat aaaatatctt gtcgctcttc ttctggtaac tttctaagat
     6421 gacttgataa ttctttaaga aactgctctt tactcatccc attccacccc ttcaataatt
     6481 tcttgaacac ctttagcaaa atcacgccac tctgttacta ataaagtaag ttgcatctct
     6541 ccttgctctg ttagttgata atatttacgg ggcggtcctt ccgtggattc ttttaaatac
     6601 gtttgaaaat atccctcttt cgttaaacga cgtaataacg gatatacaga accttccgat
     6661 attaaaaatt tattagagat ttgctgaaca agttcatatc cataacaatc cttacgtttt
     6721 acaagtgcca atacacacag ttctaacaca ccttttttaa actgaacgtt caaggacaat
     6781 ccccctttct cattttagta ctgttcaata aacggtagct attttatcca taatatacca
     6841 cttagtattg tttattgcaa ggtactgaat tatatttatt ccctaaattt agaaaacaca
     6901 aatataaaag cccgaataag accttttgta actgaccatt atccgggcta tcattcaact
     6961 cgaattacaa taatacaaga tttcattcaa tctttctcct ctatgaaccc acttccattt
     7021 gtgaccctaa taaatttcga aatacacctt ttctctcttt agccaattga ttaaattcac
     7081 ctttttgaac aatctcacct tttcctaaaa caataacttg atctgcattg cggatcgtag
     7141 ataaccgatg cgcaataaca acaatagtca tcgttccttt caacctttct attgctgatt
     7201 gaatttttac ttcattttca gtatctaatg cactcgtagc ttcatctaat actaaaatgg
     7261 atggttgtct taaaatagct cgagctagta caagtcgttg acgttcacca cctgaaagtc
     7321 tcactccacg atctccaatg agagtatcaa gcccttttgg aagcattcgt acaaattcag
     7381 ctgccgccgc aaaatctaat gcagtccaaa tttgttcttc actcgcattc ggctcaatca
     7441 tcaataaatt ttctcttatg cttgcattaa ataaaaaagg atcttgtggc acataactaa
     7501 tagcccgtct caatgacaat aaattttcac ttgtaagagg agttccatct attaatactt
     7561 gacctttctc tggctgaatc aatcccatta aaacatcgat taatgtgctc ttcccagctc
     7621 ccgaatgtcc cacaatagcc gtcatactat tgattggtat tttcacatta atattttgaa
     7681 gtgcatacaa atgctccttc ttattatatc gaaaataaat acccttacat tcaataccct
     7741 gctctataca aatcggcttt atatgttttt gctgatgtat atcctgcatt tcaattgctt
     7801 cattacattc cccttgtaag tcccataatg acttaaaagc aggaatgctt gcagcaagct
     7861 gttctaaatt tgactgaatt gtcataaatc gtggccatag tctcgaaaag atgagtatga
     7921 ttaatagtaa ttgggtgggt tgagctttaa atatacttac tgataataat ataaaaaatg
     7981 caattaaaat agccattgaa actttataaa acaattgaga gttcgacctt attctcatat
     8041 actccatttg ttcattactc atcttttctg ttatagattg taaccaatct aaacgtgatg
     8101 cttccaaagt attactcttt atatctttaa ttccattaaa atgatctgtt ataccagaaa
     8161 gatagtcttg tgctaatttc gaggtcttac cgcctagtat tcgtgctttt tttataaaag
     8221 cacgagaagc tactaagaat aataagccaa agaccaaaac aaatatagtt atttggggag
     8281 ataataaaaa cgcaagcccc acctgtatga atgtaaacag aataacagct aacaattgta
     8341 aaattaaatt aaccccataa cttacgcgag ctaattctgt agttaatata tttattagat
     8401 ttgttttcct tttctctaaa aaaaaactcc acttcgcttt tagaatcata ctatatgttt
     8461 ctattcttaa ttctcgtaca aaagcttgtt gcgttctcgc atcccttagc gttatgtttc
     8521 gttgtaatag attttgccct aacactatta gtatatatat acctaaaata gaaattaggc
     8581 ttgttgtttt agggaaatcc tgcaaaaatc tataaacagg tgcaataaaa gcagtctcct
     8641 cacctatatt aattattcca gccatactta tcataggaat taataaaata atacctatcc
     8701 cttcaagtaa acttattaaa accataccaa acaaattcac atacagaatt ttccctgcag
     8761 aagaatataa tttcttcata aaatatataa tatgattcat cgatgttccc cctatgacaa
     8821 agcaagcttc tttgttttcc tccaaagaca tagaaacgga cgtaaaggaa aatataaaaa
     8881 atgaaggaat ttaggtaacg gcaatgtttt tgcatcaatc ggataaggat agagttggct
     8941 cataataaat aaaatttttt gctgattaga catcagtgaa aataaatgcc tactatgata
     9001 agcaagtact tcttcaggaa caggatcggt atgcaagttt atcatttgct tgaaataaaa
     9061 cagcgcttct tgagctaact gctttgaacg ttttttcgct actaattcca tcatcctctt
     9121 atctaatcgt gcacctaaca tttgagatgc caaaattaat gcttgtcctc ctaaatgaaa
     9181 catttgatat tttctcatta atttgttaat ctcactccag ttaagatctt gattgacaat
     9241 tttttttata tccactaacc agcgcaatct agaccaacca tgtctagcac catgagagac
     9301 aagaaataaa aataaatctt cctttcctaa catatatacc gaattacttg taagtgcact
     9361 ttttctcttt cgcttccaaa gctcttcaaa cccaggttcc ttacccggtc caggatttaa
     9421 cctccaatga atttcaagtt tgatccgcct tgttggatgg aaaaatgtta tatggtgatg
     9481 cctccatttc caatcactta atatcgtttg aatataatca tctttcacat atccttgctc
     9541 taaaagtagt ttttctactt tttctaattt ttgaacagga atgagaacgt ccaaatcaca
     9601 agatgttcgt aaagaaatat ctccatataa gtcctgagat agtacaggtc cttttagaaa
     9661 catcgtacga atctcatttt cattaaaaaa tttatttatt cgttccattt cagcacttaa
     9721 ataaagcatt tgaaatgtat tatttctata ttttctattt aaagtttgta caacatgtga
     9781 aggaattcgt tcctcatcta cctgtttaag tttttgataa atcaccggat aaacacgatg
     9841 atgcatggct tgctcaagaa aaacctccca atcaatatct gtgaaccatt cactactata
     9901 agtttgcagt gtttcgtcat cttgtaactt caaaattgta aaaagaagtt tcaattcctt
     9961 agacatgaac tctacattaa gaccaaaatc tttctccatt ttattctcct ttaatagtgt
    10021 cctcacttaa cctctttgca aatgatccaa cgacagtaaa tttctccatt ccttctgatc
    10081 cagtaacata aaaagaaccg ctccgtaacc atgcatgcgc aattaattca ccatgactat
    10141 ccttagcagt tcctaaataa agagtactct caatgtgacg tttttcgagc attttcatcc
    10201 cagctatagc tttaacgaga cattgacttt cccaaaaagt ataacgactc ataatagaaa
    10261 ttgcttcgga cacctttttt agcgtatctc cgtgcggttg aatatgagta cttgaggttt
    10321 cactcatgta atcccctaaa gaaggtgcaa ctttggaaaa tgtaatattt tttagtacac
    10381 gtgcccatcc taaaaaaata aaagcctcta aaaataagag ctttgttttc atgtttagtg
    10441 ataaaaacat ccttaacctt ttcacaatat ttattaatcc cttcctaaca gttcttttga
    10501 aattacgaat ctatctatta ggctgatctt ttatttgaat taacccttct tgaaacaaac
    10561 actctaaaaa ggaaagaact tgctcttcac aatcttttcg ttcaatatca tagttagata
    10621 ctagcatagt aacaagctga ttaattatta ttggcttttc aataagctcc catatttctc
    10681 cgcctatttc acctaagtta tagtaatttc ctttctggac atttaacata actttttctc
    10741 catccatatc gcttactata ttacccttac tttggacaac gttatgttct aatgatattt
    10801 ttctcgagtg gacaaccatc aaccatactc cctttctgta tagtatttaa aataacttcc
    10861 acaagctcat gagctgtaaa tcttgaagcc gggcggctta cttgaaatat ttccattcca
    10921 cttgcaatat tagatgaagt ttcaaaatgc cattccatca atcctaattt agaaatcaaa
    10981 gaattcctaa aagtatggcg gtataattta tacaagcgtg cgagcccttc tatacgggtc
    11041 atctcgatat cttctccctg cgtttttact aattcaataa caccagcaag aggtaatgga
    11101 tcaggaaaga attgagaatt cacaggaaca gcatacttcg tttccctttc aaataaaggg
    11161 ctaaattgcg ctacttccat tcctaactca tttatgctct cttgccataa tttttgttgt
    11221 gcgtaagaag gatgaactat tgcagtattt ttattcaaaa gagacacagc aactacatca
    11281 tcacttaaaa gcttatatcc tttattcaaa aaagccgagg ctaacgttga ttttccagct
    11341 cctgaatcac caattaatgc atatgctttc ccatctatag caattacact cccatgcaat
    11401 gggagtattt tacgttgcat taaaagcgcc cccatacaag ttcccaaaat atatagtcga
    11461 attttatctt cttctgcatt tgccataggt gaaaaggtga ttttctcacc tgattgtata
    11521 gcgaatattg cagtttgagg aacatgaaac ataactatat catcctccac tactatcgtt
    11581 ttttgctttt ctgcgctata ttcaccccac tgttctgaca aatcagttat ttcaacttga
    11641 acatccgcca tctctttttt ttcattcagc tgagacaatt caggtaatgg gatttcactt
    11701 actattttta acccgaaggc ttgatataac acattcccca tagaatcaaa catcctatcc
    11761 ccccacattg tcaatttttt gaaagctctt atataataaa gctatataag agctttattt
    11821 ttccaatgac ttaactgtac ttcactggat catctgggtc aggttgaaca gcatctggat
    11881 atttatgccc aggccccgcc atagtcatat taatattaag tacttctaat acaggttgtt
    11941 tccattcctt tttcatacgt atcacctcct ttcacattgc tttttttata aatcgataga
    12001 agattaagct acgcattaaa attctaaaat ctaaatcaaa tgcatattct ggtcgaggtt
    12061 ctttacaaat ttttgagata gctttcttaa ttacctcgac atttagaaat tcagaaatta
    12121 ctggatctac actaagttct tcaacttcct caataaattc attccaaaaa ggagccatac
    12181 ggtaaacacc atctgcacct tgaatacctc gaacccgttg attcaatcgt actttatcag
    12241 gaaggaaatt ctttgtggct ctccggatca gggctcgatc caaaccattt tgaacatact
    12301 gttcttctgg aactgacaaa caaaattgaa tcaatcgtaa gtcatttgtg ggatcacgat
    12361 cccataaagc ataacgtaat gataatttcg tttcatacgt tccatttatg ctccaataat
    12421 atggtttttc aaactgttct cttttcatgt catatgcatt agagatagag gtgcctgtta
    12481 tatcgatgtc ttgttctctg agtctgtcaa aaacattcat ttcccttgca aattccggat
    12541 taattattgc ggaatttgca tcttgtttcc ctgaaaaaag taactgatgc aaaaatggaa
    12601 atgcctttcg tcttaccact tcaaaaacac gtgatttttt cactcctata tttctactat
    12661 ataaatgtag ttcacgataa aaacgaatcc aatgtagctt tttcaataac attgcctggt
    12721 aatctaaaat aggtccccac gatactgtcc aattacctct ttgaccacta agaagtactc
    12781 ctattccatt ctgagatgct ttttcataaa ctccactcaa ccaaaaagta ttctcaaaaa
    12841 atttatatgg catctccatt gtttccagcc aatcatcaat ttccgatagt gggcttctct
    12901 ccggcaattc taaataataa tcctgtatat tccctacatg ctcgacagtc gattgaataa
    12961 atggtctttc gtcagctatt ctacctttgt gtgtccaatc ttcaaatcct tctactggaa
    13021 cataactgta cgtatgtaat tttttatttt cagcccgtaa atcacttgca gcaaaactaa
    13081 cgacagaacc tgagtctagc cctccgctca aatgagctcc tacttggtga tgtgttcgta
    13141 aacgtgcctt cactgcactt tgatacacct ctcgaaacgc ctcttcatac tcttcatttg
    13201 attttaaatt aagcatttcc ccaacagttg gtgtatagta tcgcgaaaac ttcacttcgc
    13261 cttcctttac caaaatagtg tgtgctggag gcacttgttc tatatatttg taaactgtta
    13321 actgtggatc taccgattcg aaatttacag gtatagctag aaattcagca atccactgct
    13381 tattcaattt cttctcaaca tatggtagag aaaataacgg atttataata gtacaaaaag
    13441 taaatttttc ctcaccacga taaaaataaa gtgtccgact tcctgaaaaa tctctggcac
    13501 caaaaagaat ttgttttttc tcatcccaaa tcataaaggc aaaatcgcct accaaatatt
    13561 ttggagccgc ttccccccat ttttgataag agagtaaaat taactcgcta tctgtcatgt
    13621 tttttctatc cgaataatcc acttgtaatt tttcaaataa ctcatcacga ttatcaataa
    13681 tagcatctgc tgtaattgcc agttgctttt cataattata aaagggtaat tgttcaccaa
    13741 ctgactctgg tgtaatccat tgtgcatgac atcctagaaa agcattttct ttgtgccata
    13801 tttgaatatc atcggcagga tatttgtata aacgactcat tacttctctt ccgtgctcaa
    13861 ttgatacagg ctcattagta aagtgaataa tgccagctat agcgctcatt tcttcctcct
    13921 aatatatgaa aagttactac aaatactatt tacatattaa attcgttaaa catacctctt
    13981 tatcattctt tttaacgaac gaaattattt gttttattac tttctcaatt acatgcttaa
    14041 atttactttc agactaagat atagatatta aaagcctata attatccctt ttttatgtca
    14101 attgaaactg aatgttccca aacaatcccc tttggaattc actataaaga acaaatagtg
    14161 gtacatatac aaatctaatt ccaattttac ttacttttct tttaattctt ccattctact
    14221 gcttttaaaa tgctttgaat taccctttgt tgatcttcag ctaacatatt agatcctgaa
    14281 ggcaaacaaa ttccactttg aaataaggaa tgcgacacat cttcattttt actatgcgga
    14341 taatacttct tctctttaaa gagcgactgc atatgaagtg gcttccacat aggacgcgct
    14401 tcaatattct cttctgctaa agttctcaac aatttcccaa tagtgatccc ggattccttt
    14461 tcatcaattg tcaatgtagt aagccaacga ttagagcgag tattttctaa ttcaggcata
    14521 aaataaaatc ctggcatgtg agatagcgct tcataatacc gtttatatat aaatcttcta
    14581 gctctcaccc tatcttctaa cacttctaat tgtcctctac caataccagc taaaatatta
    14641 ctcattcgat aattatatcc tatctcacta tgctcataat gtggagctgg atcctttgct
    14701 tgtgtcgcta aaaacttcgc tctctctaat gcttctacat cattagaaac tagcattcca
    14761 ccacccgaag ttgtaataat tttatttcca ttaaatgaat aaacaccaaa cctaccaaat
    14821 gtaccgcttg cttttccttt atatgtagaa cctagagatt ctgctgcatc ctcgattata
    14881 ggaacatcat attgattaca gagcgaaaga atttcatcta acttagcact ctgaccatat
    14941 aaatgaacaa gaatgacagc tttcggtaat tcccctgctt tattagcatc atataatgca
    15001 agcgctagcg cttgcggtga catattccat gtttctggtt ctgagtcaat aaatactggt
    15061 tcagctccca aataaacaat cggattcgca ctcgctacaa aagtaaaact tgaacaaaac
    15121 actgtatctc ccttttggac atctaataat cgcaaagcta aatgaatagc agccgtacct
    15181 gaactaactg cagccccacc tttcactcct acaaaagatg caagttctct ttcaaatcca
    15241 tcaacatttg ggccaagagg ggcaatccag tttgtatcaa atgcattttg aatatatttt
    15301 tgttcatttc cactcatgtg cggtgaggaa aggtaaattc gctttttatg ctgaactgtg
    15361 tgcatgtaaa cacatccttt atacatattt aaatactatg tatctaaaaa catatgctct
    15421 aatacagata tatcagataa tctccttaaa ttatcaattg tataatgtgc tttataagct
    15481 tgctcaacta taagattatg atgaattcca ccttctctat taatatggat cgttaaccat
    15541 ttcaatttct tggctgttat aaaatcctta cttaaattat ctcctatata gacacattgc
    15601 tgatgaggca cctgtagttc cttacttatt ttttcataag gaatttggct cggcttccaa
    15661 tattcttttc ccagctcatc agtgagaatt atcgaatgaa atctctcttt taactttaat
    15721 gcattaattt tcttttcttg ggcaactaaa tatccgtctg aaataagtcc tattttaacg
    15781 gtattaacta aattatttag tacccaatcc gcttcatcca acaattgaat atctggttta
    15841 tgaaacctat actgttctat caaattacta atcaattttt catcgtaagg aatgtttaac
    15901 ttttctagtg tttcattaaa cacgaacctt ctttcccccg aatcgaataa ttgaattgca
    15961 atattataaa atccggtttt cttatacttc tctttaatcc aatcatccac tgctttaaaa
    16021 ccacttacaa cataatcttt ctctttatat aaagtatcat ccatatcaaa aacaattgct
    16081 ttaatcatca tcttaaatac tctccataaa aaccgcttca tcatatctaa gcattgttaa
    16141 attttctctc caattaaagt ccttatctat aaagacttcc ccctgacaca ttttaattgt
    16201 ccaaagtgga aaattcgctc ctgcttctat tgatagtggt attcctcctc caaaacgagg
    16261 gtttatttca ataaacgtaa tttgtccatc ctccttttta aaacattgta aagtaataca
    16321 cccaatagga ttaggaagag cttttattac agtttctgct gcttggatga tatcaaaatc
    16381 cttcttggtt atacctttac ttacctcacc tgctcgtgtc tctatacgca atctaggaac
    16441 gattgttttt atattcccac agaaatctac catgacatct atagtgtatt cttctcctga
    16501 aacgtactct tgtatcatag cgttaggtat ataatcctta aaaaattcca attccttttc
    16561 attcattatt tttgttacac ctttactaga actgccatca taaggtttaa ttaatagtgg
    16621 aaattgatat tcttttcttc caatctcttc atcactatat actctaggtg ttggtatatt
    16681 attagatgca aaaaagttat atgtgtattt tttgttatta gcaatcttat ttaattccat
    16741 actagaaact aatactttta caccaatacc ttcgaaaacc ttcgaattat tagccataag
    16801 ggttaattct gtatcaatta acggaattat tagatttatc atttcagatt tacatatttt
    16861 taataattca tttatatatc cctcttcatt tacacgcgga acaataaaat gcttatcgct
    16921 aaagtaaatg gtgggagcag tttcttttaa gtctgcagta aagatttttc ctttgattcc
    16981 ttcttgttta agtacttcct taaatttttt aattaaggtg accctcctac cagagctagt
    17041 aaacaaaata ttcattttat tcccccccat gctcgattcc ccccttaaaa actggcatag
    17101 tcacatgctt attatttgtt atcccttccg actttaaaac cttactaaaa gttagatata
    17161 aaattttcaa atctaaaaga aaactttgat tctcaacata ccatacatct aatttaaatt
    17221 tctcatccca tgagatacta tttcttccat taacttgagc ccatccagtg attccgggtc
    17281 ttacattatg ccttttagct tgctctttcg aatataaagg catatattct attaataatg
    17341 ggcgggggcc caccaaactt aattgacctt ttagcacatt tattaattgt ggtaattcgt
    17401 ctaaactata ttttctaaga aattttccaa ctttagttaa tctagcgtga tcttgtaaca
    17461 gctccccatt acgatctcgc tcattggtca tcgtacgaaa tttataaaga taaaaaggtt
    17521 ttccatgtaa ccctggacgt tgttgtctaa ataaaatggg tgatcctatc tgagttttaa
    17581 ctataattgc tactaaaaga ataacgaaaa aaaagcaaat taataataat aaagaaataa
    17641 agatatcaaa cagtctcttc attaccaatc attcccccat cttaaattat tacaaatgct
    17701 tttccaaagt taaataatct acaaagtatt cattacggat tgaaatcaag tattcttaag
    17761 ttgtaattaa agaattgtat tcaatttctc tttacttatc acctgcaaac attttctata
    17821 gtacacagct ttaaaactta ataagtagaa gaaagcaata cacataggtg caaaatatat
    17881 ttttccaaat gcttatccaa gagactatta cacactgtaa aaatctcaaa aaatatattc
    17941 acaaacacag ttttataaac aacgcttagt agtatattaa aaaatccatt tattatttaa
    18001 aaattctcct acacactatt ttttagtatg cagttaacgt aataataaaa agctattatg
    18061 tttataaaaa acataatagc ttttctctat tctatagtag taactaaaag tcaataaacc
    18121 tattatctat taggaattag actatttcga ataattacat tggacaaaat ccttccatgt
    18181 accattatat aatactttat ggacatattt attaagagcc actctacttc atttctcata
    18241 attttttgaa actattcaaa tttaattatc accatgcatt aatttggatc tattacacca
    18301 ttaactatat tcccttgcag aaattccctc cctgtaattg taattttcgc attattcaac
    18361 acgttgtttt gaattactac taggggtgta atactcgttg ttctattatc tatcccaact
    18421 tgcatcaaat ttgtggaatt tataatatta ttttgaatta tcacttgctt accagtaaac
    18481 gctgcatcca aaacaataat agctctctga agagtatcat ttgtaatttt tatagtattt
    18541 ccccctaaca ctatttcatc agatacattt tgaatattca agaccgtacc atttggtttt
    18601 tctatatgac aatccatcat cttgaatgct ttgaggttat tcactgtaaa taacgtgtta
    18661 tttctatcta tactaaagaa cttgcaatct tttaattcta aagtgcttcc tgtacttgtt
    18721 atccccaaaa aggttacgtc cttaaaaaag caatttgtat atgtccctgc aactaaggtt
    18781 gggtttttaa cattattaaa tataatattt tcaaatatcc atcctgattt aactgttcct
    18841 actggtacat aatttaaata caaaacgtct tgtccttcaa atatacaatt tgagatagtt
    18901 tgcggctcat ttttcatctc taatgtccac tgatacaatg atgacaagga atttagttta
    18961 tctgcatcgt ttataaagcg acaggaatca actttaaccg catatggaaa gggggtatca
    19021 ataatcattt tactattaga aaaaatatta tctaatatat taataggtcg atttacatat
    19081 acaccttgaa catttacttg cgctccgtat acataattat tggaaaaaat aacatctcct
    19141 aacaaagaga ccttggttaa tcggatatta ttccctgtta cgattaccct atctgcacca
    19201 ccattaatag atagcccaac ataagcattt gaaatggtat tcataataga attattcgat
    19261 atatagataa atttcccatt tacaacaata atattataat ttttattatc atgaaaatta
    19321 tttctttcaa tgtatatata ttgatttaaa tcatatccat cttcaatatc tagtccactt
    19381 tgtggattgg tacctgcgat gtgatgaata tcattatctc gaatatatac attctttgcc
    19441 ccacatacac taatcccttg tctacggcaa tcatgtaaat tacatttttc tatataagta
    19501 tattgtgaaa aagaaggcac ccgaacattt attaaacaat ttgcaggagc aggaacattc
    19561 ccttgatgca aaacaatttt agcataactt gctccattag ggacttctac ttcatcaaag
    19621 aattgtacat tggtttttga agataaaaat atattatttg aagtgtaaaa aatgacatca
    19681 taataatcgc attttatttc agaacccaat gctccaaatc catttccata taatccaaag
    19741 taaccatact ttacaatagc cacttgggtc atatcaattt gcaaattgga acgtatcttt
    19801 gttgtactac ttactaatga accatctgtt gtattaattg ctccctgttc aaatgaactt
    19861 gctaatgctg taggaaaagg tgaaatctgc ccaaaagtac tgttcagtgt aatggcatct
    19921 cctgtacaat ctaaaatatc tagattatct aaagatacaa accgtgtatt gttcccccca
    19981 tcagcaggtg gagtaaaact ccccaattca atgccgtacc ctgcctcatg tgttccccca
    20041 ctagaataat catgtgtata tctatctcct tggataatac catttgttat cctagaatat
    20101 acttgatttc tacgaaaact tataattgca tatccagtca aattatttgt ttccattttt
    20161 aatgttgaac cgtttagatt caaagttaaa tgacttggtg gttcgatggg tgtttgttta
    20221 tcaatcaaat atattcctct aggtaacaca acttccgtat aaccttgttg agccgcccaa
    20281 actaaagcat tattaatacc tttggaagta ttgatagcat cagtcccatc attcttaaca
    20341 tcccatctat ctaattctaa tacatatata cttgtagaat ttgtagcttc aaatgatttt
    20401 ggaatccatt ttaattgcgt actatcataa gttaaaatgt cattatgaaa aggaggcttg
    20461 gacaccaaat ctaaatcatt caaattccca agattatccc ttcttctcca catcaattca
    20521 cacctctttt ttgcttttct acatcttatg tttcataagg taaattgatt ggatataaga
    20581 gaagtaacat cactttttat tgtttttaga gatccattat ttagaaagtc ttttcacaat
    20641 tcctttctcc ttcctaaata gatctattct tactagctgt ttttatttca ataccctttt
    20701 atttatacta tttaaactta caattttatt aaaaagacac tatgctcttt atacataact
    20761 cccctactat tattttcaga acaacctaaa atctcttccg taaataaagc attctttact
    20821 gtgatatgga aaaaataaaa taataattta tggataatta tcattcgaaa ctttccgagt
    20881 taatattttc gactttattt tttttattaa tattcgggtt aaattaagga aatatctata
    20941 ctcttccgcc tctttaaata ccatccaaaa gatcaaattc ggaataatca ggcacaaaat
    21001 actacgtatt accatgtcca taaatatatt tatgtgaaaa atataaccaa taaaatccgt
    21061 tgctataaca gaaaataata caagcactac aaacaaaata tatctaataa aatatacttt
    21121 tacagatttt ttaaaaatca ttttaaatat aatataagga tcataccaaa agtaagtaca
    21181 taatctacta ataacagtcc ctaaaagcac tcctgctatt cctatttgtt tcgcgagaat
    21241 tatagaaact acaatattta taattgccgc tatgataggt ctatacttcc cttttttaaa
    21301 taaacctgtg gtttctctaa aaattgtagt tgtattttgc attcctgaag tgaaaaaatt
    21361 aagtaatatg aaaaataata catacttatt aaacacatat tcctcaccta accagagtgt
    21421 tataaatgga tttatcaaat tccaaaggca aactgtacaa aatccatata tccaaaaatt
    21481 aaaaaagtta attacacgaa aaataaaata ttttttttct gcattttctt tcacattcaa
    21541 atttccaaca ctagcagtga tagaataaaa caaatagcct aataaggtat ttaatgtatt
    21601 taagatcaac aaataatttg aatacacacc aacccaaata attccaatga atttcgatat
    21661 aattatatta tctgttgcat taattactac accactaatt ttatatagta acaaggaata
    21721 caaattctca aaaaactctc gtctgtctgc cttagataat ttcgcattat ttttttcttt
    21781 taaaaatgga tataatttat ttgccttatt tgcaatatat acattctcaa ttactttcaa
    21841 tgttaattga actatcagta ctacaatgta atcactaata attattaata aaacaatttg
    21901 taatgcgtta gatataatta tgaacaaagt gtgtatttta gaaatgatat agttactttg
    21961 atcagcaata ataatagatt gcttatatac aaaataatat gatgacaccg aacttattaa
    22021 aaataaaaga tagataatgt taatgtcttt aatcatagta tctgcattca ctaaataatc
    22081 aagaaatggt aatagagata accctaataa taaaactact actcctatta atctgtatgc
    22141 tttttgatat aaattcatta atgcctgtat tttatagata tccttctcag ctaatggcct
    22201 atataaacta taaattatag ctgtatcaaa gcctaaatta gctagggaaa acatcaatag
    22261 tatacttgta aaaagcccat ccacacctaa atattctata ccgagtgtat aaataaaaac
    22321 agttcgaaca acaaatccca tgccaatact aattatttgt ccagacaaac cgaataaaat
    22381 attttttaag gaattttgta ttctcatcgt aataccttct atattttagt tgttttgcgt
    22441 acccactcta ctaaatttgg cactaatctt cctctttaaa atagggaaaa actttgttat
    22501 cctgtatttt aataacgctt ttcttcgttg cgccttgaaa tcataatcta gaaaccaatt
    22561 tagtaaattt ttatctgtaa tacaatcaca attttgtttc attcgcactt ggattaaatt
    22621 ccaatacatt tcaatgaatg tattagtaaa aaacttcacc tcactattta aagaagtttt
    22681 aacgtactga taaagattac ttggaatatt aaaaccatat tcacgaggat ctctcccttc
    22741 agcaataatt cccataattg ttcttaaaca tttttcacat ttacaacaat tttcttcatt
    22801 tttaaaacat accctgatat taacaggttc tttactagct gaataatggt ccacaacaac
    22861 tttaatcttt tcttgcctag taagttcgta tccatcatga aatactgttc cagatgcata
    22921 ttttatttca ttatccacag ttggatcaga tgcacaagta acttgatata atggagaatt
    22981 agagcttgca atgtatatac attttatctt aagtttaaaa gctattggaa tagctgcaga
    23041 tattatcgct agaccatgat gcaatccatg ccaccatgta tcgtttaact tttctctaaa
    23101 atcatggtca atgttccctg caattataaa ggtcccatag ttggattgta taaaaatatt
    23161 ttctagtcca ttatccttta caaaatttat ggcattttct ttatctgcct cccatacttt
    23221 actaccctct atttcatttt catgccatcc atattcagta actagcaagg ggtttttatc
    23281 ttttattctt ataaatgtag taagtgcatc taatccccca ctaaataaag atgccgcttc
    23341 aaattccgga atgtaaacat tatcaataat ttctcctaca tccacggatc ctttaaattt
    23401 cacaccagga aacatgtttt gatatgcatt ttttatatta tttaaacaaa tataaaaaga
    23461 tttatctagt tcatttatta ctattgttga attagtaatc catacaagag gaactacatt
    23521 tgcaacaaac ggaatagcca aaatacttaa agggatatca gatacatcat agttatattc
    23581 aagaaacata tgattacttg tcttaaaata cttttgtaaa tcccccttaa tactaaaaga
    23641 ataatcaact ctattatttc ttacgacaat tttatcgaga attatactat tcatttgagc
    23701 ctcctaataa atcgccattt ttatcaaagt acatttatta attagagaac tgttttaacc
    23761 attgatttac tacatcaaaa ttcacttgaa catccgtgat aaactctgaa tttatcattt
    23821 tttcaagatt atttaaatct tccctatcaa tcagatttaa attatacgtt tcgcccatcc
    23881 ccttagctct ttcatctatg gagataatt
//
