LOCUS       NZ_CP059997            25211 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10301126
            Orig. end                         :: 10326337
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25211
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="50"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25211
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25211
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15211](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15211)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(277..291)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
     misc_feature    478..493
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.13"
                     /tool="antismash"
     misc_feature    1089..1102
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    1098..1112
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    1506..1519
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(2268..2561)
                     /locus_tag="HUW46_RS47750"
                     /old_locus_tag="HUW46_09484"
     CDS             complement(2268..2561)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS47750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_09484"
                     /product="hypothetical protein"
                     /protein_id="WP_215545217.1"
                     /transl_table=11
                     /translation="MTDSSTNTPPSLRVATRWFAGDCLPHLYRVGELEDEAVNLLQPPA
                     HVSPYHDFHPRSQISAKRIPAPAALIGTCPKCARWIQRNRYTVLLAPGEVWV"
     gene            complement(2624..3817)
                     /locus_tag="HUW46_RS47755"
                     /old_locus_tag="HUW46_09485"
     CDS             complement(2624..3817)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666946.1"
                     /locus_tag="HUW46_RS47755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09485"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_215545218.1"
                     /transl_table=11
                     /translation="MDATIGRNIREARERRGLTIRAAAELSGLSYGYLAKIERGEKPVT
                     KRGALDSLALTLRVSPADLVGKPYPARDPLGEELREGMGRVEDALTGWRVDEKPDAAVR
                     PWREIASEIDLLNKVLRPNADYLAQATLLPKLIPELLALAADQTYRRPALLGLIGTYKS
                     IAYVSLDLGIPGVPSLAVERMRQAAEELEDAEAIADVAWRRAQIIGGRNRFRQRELASA
                     IADDMQVPKHLRGMANLTAAMASAVVGDEDTALGRLGEAAELAAIIDTDDRPWTRTDFT
                     RTNVDIWRVSIGVELGYGPKVAELAQRGRPPQPLRVAHRQAAFWSDLGRALLPEKSSRA
                     RGISALLKAEQLTPQKIRTNVFVREIVSNQLHRVRRDSDEGRELRGLAWRLGVAPTG"
     misc_feature    complement(3626..3628)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3957..3970
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.75"
                     /tool="antismash"
     gene            complement(4131..4559)
                     /locus_tag="HUW46_RS47760"
                     /old_locus_tag="HUW46_09486"
     CDS             complement(4131..4559)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419142.1"
                     /locus_tag="HUW46_RS47760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09486"
                     /product="DUF1801 domain-containing protein"
                     /protein_id="WP_215545219.1"
                     /transl_table=11
                     /translation="MSSFTVEERAAMKEHAKELKTAARRASQADKAAQAERDVLAKIAE
                     MVPADRVLAERVHAVVTAHAPVLEPKLWYGMPSYALDGKVVCFFQSAEKFKARYATLGF
                     SDQAALDDGPMWPAGFALTDVTPAVEKRIATLVAQAVR"
     misc_feature    complement(4599..4619)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.34"
                     /tool="antismash"
     gene            4668..5243
                     /locus_tag="HUW46_RS47765"
                     /old_locus_tag="HUW46_09487"
     CDS             4668..5243
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417768.1"
                     /locus_tag="HUW46_RS47765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09487"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215545220.1"
                     /transl_table=11
                     /translation="MATEPRRRGAARTDELLRTTIELATEGGYAGLSIEAVARRAGVGK
                     HTIYRRWPSMAALLLDALSRVWTTDLDYHDTGDVRADLREQFLRSAPALAAPPIGPVYR
                     ALIAEAQADDTLRATLHDRFLRTVEERTLARIVRAQRAGELVAGADLTFPAEVLCGTLY
                     YRYLLSTRLADEKAVDALLDMFMAAYGH"
     gene            complement(5305..7296)
                     /gene="ligA"
                     /locus_tag="HUW46_RS47770"
                     /old_locus_tag="HUW46_09488"
     CDS             complement(5305..7296)
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635616.1"
                     /locus_tag="HUW46_RS47770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09488"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_215545221.1"
                     /transl_table=11
                     /translation="MDAGKRIQELADQVVALRDAYYRGSPKVADAEYDELEDELRGLIE
                     ANPDLAPEPNPLERVGAPTVLHAPVRHSRPMLSLEKATKPEQVVAFFDRFPGQPVVVMP
                     KLDGLSLALVYEDGRLARAVTRGDGTTGDDVTPLVRVLTSGVPERIDAPGRVEVRGETV
                     MLRSTFAAYNAAHPDKPLINPRNAAAGTLRAKDPATVAERRLQFLAFDLHTDPDSAESD
                     LDGALRTLGFAAADMRHCADAEAAQAVISEIERRRNELDYDLDGAVLRLADRDAYAAAG
                     TRSSSPRGALAFKFAAEEKTTVLSDVVWDVGKTGKIAPVAWLEPVFVGGTTVTRATLAN
                     QEVIRARGIKIGDTVLVRRAGDVIPFVAGVLDESKRTGAEVEIVPPADCPSCAQPLTEQ
                     GNSRELFCTNVSCPAQTVRRLIHWASRAAADIDAIGGVWIERLAEAGELEHPSDFYRLT
                     KERLLEFDRVGEVSATRMIESIDASRAVGLRRALIGLAIPMASDGTAARLCRAGFGSLE
                     EVADAGVDALVAVEDIGPKVAASLVEHLTRLRPELERLRERGVSLDVREEDLPPVVAAG
                     APLAGKTVVVTGAISDPRSGEKVPRPTFQRLCEKAGASIASSVSASTDMLITGAEVGAS
                     KLAKAEKLEVEVVDQGEIWQQLIDAKVV"
     gene            7414..7761
                     /locus_tag="HUW46_RS47775"
                     /old_locus_tag="HUW46_09489"
     CDS             7414..7761
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073579.1"
                     /locus_tag="HUW46_RS47775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09489"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_215545222.1"
                     /transl_table=11
                     /translation="MADILDFHRNRTPDREPDPEPEPLWREALGRSLRGMREDRGGRLV
                     DIAERAGISPQYLSEIERGLKEPSSEMIAAVTGALGIGLPDLLTGIAGEVRRYHHPRPV
                     RRPAGPLLMAA"
     gene            complement(7766..8356)
                     /locus_tag="HUW46_RS47780"
                     /old_locus_tag="HUW46_09490"
     CDS             complement(7766..8356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662156.1"
                     /locus_tag="HUW46_RS47780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09490"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_215545223.1"
                     /transl_table=11
                     /translation="MSTYTIPNVITRDVRGERVMDVYSHLLSSRIVYLGTAIDSGVANA
                     LIAQLLHLEADDPDQHINLYINSEGGDPSAMLALYDTMRFIKAPVATTCVGQAVAASAV
                     LLAAGESGHRSVLPHTRVVLHQPAAQGRGTIPDLILQADEVVRVRTQLEEILSAHTGRE
                     VADLRHDTDRDRVFDAAGAVAYGLADTIIDHRP"
     gene            complement(8353..8979)
                     /locus_tag="HUW46_RS47785"
                     /old_locus_tag="HUW46_09491"
     CDS             complement(8353..8979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629840.1"
                     /locus_tag="HUW46_RS47785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09491"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_215545224.1"
                     /transl_table=11
                     /translation="MTNDDKQPLFDRQLRERFYSQRVLVLDGTLDDDNGTVLATQLLAL
                     ASEDQRKDIALWIHSPGGSVPAMLAIRDVMRLVPCDVVTVTLGLACSAGQFLLSAGTPG
                     KRFALPHARILMHQGSAGISGSAVEVEVQADDLRHTRDTVLGLIAEDTGQPVEKIFADS
                     LHDRWFTTGQAREYGFIDHIVDSLDQVVPVRTHRLGLGTAAGARA"
     gene            complement(9036..10004)
                     /locus_tag="HUW46_RS47790"
                     /old_locus_tag="HUW46_09492"
     CDS             complement(9036..10004)
                     /EC_number="1.13.12.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501639.1"
                     /locus_tag="HUW46_RS47790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09492"
                     /product="nitronate monooxygenase family protein"
                     /protein_id="WP_215545225.1"
                     /transl_table=11
                     /translation="MIATDVTRLLGIDLPIVQAGMSWASSAPELPLAVSRAGGLGVLAA
                     GPMRPGDLRDAVRALRAGTDHPFAVNLPLYRKGAEEAMDLLVAERIPVLIASQGGPRRY
                     LDRFRAAGTVCLHVVASAEHARKAADAGVDGLVVVGAEAGGHPPPDLVSTLVIVRAVAR
                     AVPGLPLIASGGFADGAGLAAALALGAGAAQFGTRFLASAEANVHPAYQRAVLSASVSD
                     AQPLGRELGVIRALPNTFTREMAKLERDGASVEDRRVRFAESTLKMAAFDGDIDNGKIE
                     AGQSAGLVDEVLPAAEIVRALAAEYLATVRALPQWTDAAES"
     gene            complement(10001..11620)
                     /locus_tag="HUW46_RS47795"
                     /old_locus_tag="HUW46_09493"
     CDS             complement(10001..11620)
                     /NRPS_PKS="Domain: AMP-binding (20-435). E-value: 4.5e-87.
                     Score: 284.2. Matches aSDomain:
                     nrpspksdomains_HUW46_RS47795_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010226970.1"
                     /locus_tag="HUW46_RS47795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09493"
                     /product="AMP-binding protein"
                     /protein_id="WP_254125630.1"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-99, bitscore:
                     331.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLEALDLTGVCPLTTDEALRRAAAVVPEVEAVVHAHERVTYAEL
                     AEQVAALRSALHRVGVERGDHIGLCLGNGPRWVALFLAVTSLGAVTVPVNTRFKAPELE
                     YALRQSDVKLLFLAEKVLSSEFTAMLREICPAVEKELPDPNLPRLARVVVLGEDVPAGA
                     LGWDEFTSGAGEPVEACSDPDDVALVQFTSGTTSFPKGVLLTHRNMCADAFFSGTRLGL
                     HAGDRFYSGRPFFHVAGTTLSILACIQQLSTLVTAERFVPETALRLLADERCTHFAGND
                     TIALMLLNHPDRDEYRLSLRGAWLAASPTVVRRVIDELGAAETVVGYGLSEASPNVAQS
                     AWWEDERLRVDGSMPPEPGVSVRVRDLVTGADAEPGQQGEILVRGWNVMRGYYAMPEQT
                     AAVLDDDGWLSTGDLGVLRADGRLLFTGRAKELIRVGGENVAPTEVEAVLHRHPAIRQA
                     AVVGVPDERLVEVPFAFVVLNGSADPSPGELLDWCRGEMAGFKVPHHLRIVDGFEGIGM
                     TASAKIQKKQLAEHAVRLLDAR"
     aSDomain        complement(10316..11560)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS47795_AMP-binding.1"
                     /evalue="4.50E-87"
                     /label="HUW46_RS47795_AMP-binding.1"
                     /locus_tag="HUW46_RS47795"
                     /protein_end="435"
                     /protein_start="20"
                     /score="284.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RRAAAVVPEVEAVVHAHERVTYAELAEQVAALRSALHRVGVERGD
                     HIGLCLGNGPRWVALFLAVTSLGAVTVPVNTRFKAPELEYALRQSDVKLLFLAEKVLSS
                     EFTAMLREICPAVEKELPDPNLPRLARVVVLGEDVPAGALGWDEFTSGAGEPVEACSDP
                     DDVALVQFTSGTTSFPKGVLLTHRNMCADAFFSGTRLGLHAGDRFYSGRPFFHVAGTTL
                     SILACIQQLSTLVTAERFVPETALRLLADERCTHFAGNDTIALMLLNHPDRDEYRLSLR
                     GAWLAASPTVVRRVIDELGAAETVVGYGLSEASPNVAQSAWWEDERLRVDGSMPPEPGV
                     SVRVRDLVTGADAEPGQQGEILVRGWNVMRGYYAMPEQTAAVLDDDGWLSTGDLGVLRA
                     DGRLLFTGRAKELIRV"
     CDS_motif       complement(10418..10498)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS47795_0002"
                     /evalue="4.20E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS47795"
                     /protein_end="401"
                     /protein_start="374"
                     /score="22.3"
                     /tool="antismash"
                     /translation="PGQQGEILVRGWNVMRGYYAMPEQTAA"
     CDS_motif       complement(11003..11062)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS47795_0001"
                     /evalue="1.70E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS47795"
                     /protein_end="206"
                     /protein_start="186"
                     /score="20.6"
                     /tool="antismash"
                     /translation="ALVQFTSGTTSFPKGVLLTH"
     gene            complement(11626..12375)
                     /locus_tag="HUW46_RS47800"
                     /old_locus_tag="HUW46_09494"
     CDS             complement(11626..12375)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (5-243). E-value: 9e-49. Score:
                     157.9. Matches aSDomain:
                     nrpspksdomains_HUW46_RS47800_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501637.1"
                     /locus_tag="HUW46_RS47800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09494"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_215545226.1"
                     /transl_table=11
                     /translation="MDPVLVREEAGVAEVTLNRPEARNALNLPMCTALREIFADLDADD
                     GVRAVVLKADGPVFCAGADLKERKEKDETWVRRRRLASFAAYETIERCGKPVLAVVDGP
                     VVGSGGEIAMSCDFVLASEAATFRFPEPHWGTVGATQRLQRVIGKRRAKEILFTGRVVD
                     AVEATRLGLVTRLAAAGELERLVAETVEAIVAAPPLALSLTKQSVDLGEEAALTTGIRI
                     ELAAIERNLADGGWRRGVAEFADRSGE"
     aSDomain        complement(11647..12360)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS47800_ECH.1"
                     /evalue="9.00E-49"
                     /label="HUW46_RS47800_ECH.1"
                     /locus_tag="HUW46_RS47800"
                     /protein_end="243"
                     /protein_start="5"
                     /score="157.9"
                     /tool="antismash"
                     /translation="VREEAGVAEVTLNRPEARNALNLPMCTALREIFADLDADDGVRAV
                     VLKADGPVFCAGADLKERKEKDETWVRRRRLASFAAYETIERCGKPVLAVVDGPVVGSG
                     GEIAMSCDFVLASEAATFRFPEPHWGTVGATQRLQRVIGKRRAKEILFTGRVVDAVEAT
                     RLGLVTRLAAAGELERLVAETVEAIVAAPPLALSLTKQSVDLGEEAALTTGIRIELAAI
                     ERNLADGGWRRGVAEF"
     gene            complement(12377..13564)
                     /locus_tag="HUW46_RS47805"
                     /old_locus_tag="HUW46_09495"
     CDS             complement(12377..13564)
                     /EC_number="2.8.3.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501636.1"
                     /locus_tag="HUW46_RS47805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09495"
                     /product="CoA transferase"
                     /protein_id="WP_215545227.1"
                     /transl_table=11
                     /translation="MKPLSGITVLDFSRVLAAPLATQCLAELGATVLKVERPGRGDESR
                     GWEPRLPAGESAYFFAFNRGKRSITLDLKSERGRGIARDLAAKADVVVENFLPGTLDGM
                     GLGYEALSTVNPGLVYVSNTGFGQDGPYRDRKGYDTIFQALSGIMHLTGHPDTPPAKAG
                     VPISDLASGLWTAIAVLTGLVGRGTSGRGSHVDVAMMDVQVSLLALAAARVFAYGEDPV
                     RQGTQHPGRVPSAAFQCRDGRWLHLSASDQHWRPLCEVLGLTDLLADPDLSANAGRLGQ
                     RERVLGALRAAFAQRPRADLARALRDRDVPVGEVNSVREALDDPNTVARGMVGHFDHPA
                     EGRFPALRTPLRMAGYEDPEPAVPPRLGADTGAVLASYLGLSTTEITALREEEVI"
     gene            complement(13561..14292)
                     /locus_tag="HUW46_RS47810"
                     /old_locus_tag="HUW46_09496"
     CDS             complement(13561..14292)
                     /NRPS_PKS="Domain: ECH (9-223). E-value: 1.5e-48. Score:
                     157.2. Matches aSDomain:
                     nrpspksdomains_HUW46_RS47810_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501635.1"
                     /locus_tag="HUW46_RS47810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09496"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_215545228.1"
                     /transl_table=11
                     /translation="MPEVLLSEDEGAVRVLRLNRPEKLNALNTALTTALHDALLEADRD
                     EGVRALVLAGSGRGFCAGADLSEFGHLTPDNPAAVLARAELTSRTQSLLRELSTPVVSV
                     VQGAAVGGGAGLAIGADMTVVAADVKFGYPEMKHSIVPAVVMTGLQRQLGPKLAFELIS
                     LGRMLTAAEMLDLGLANRVAEPGDLLGEGLRIAHRWAEASPLAMAATKTLFHRVADLPY
                     AEAMRAGRDVNVIMRGFRERR"
     aSDomain        complement(13624..14265)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS47810_ECH.1"
                     /evalue="1.50E-48"
                     /label="HUW46_RS47810_ECH.1"
                     /locus_tag="HUW46_RS47810"
                     /protein_end="223"
                     /protein_start="9"
                     /score="157.2"
                     /tool="antismash"
                     /translation="EGAVRVLRLNRPEKLNALNTALTTALHDALLEADRDEGVRALVLA
                     GSGRGFCAGADLSEFGHLTPDNPAAVLARAELTSRTQSLLRELSTPVVSVVQGAAVGGG
                     AGLAIGADMTVVAADVKFGYPEMKHSIVPAVVMTGLQRQLGPKLAFELISLGRMLTAAE
                     MLDLGLANRVAEPGDLLGEGLRIAHRWAEASPLAMAATKTLFHRVADLPYA"
     gene            complement(14285..15211)
                     /locus_tag="HUW46_RS47815"
                     /old_locus_tag="HUW46_09497"
     CDS             complement(14285..15211)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501634.1"
                     /locus_tag="HUW46_RS47815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09497"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_215545229.1"
                     /sec_met_domain="HMGL-like (E-value: 1.3e-34, bitscore:
                     119.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADRVTICECFARDGLQHETGFVPTGTKLDLVAAFTAAGFRRIEA
                     TSYSHPRHVPAFADASEVLAGLPVAEGVAYKATCPNPRAVRRAIADLDAGRGAEELSFL
                     VSATEGHTARNLRTTRAAQWENVAEMTRLARGRFTLVGVVSVAFGCPFDGAVDPGSVVA
                     DIVRFAELGAGLITLGDTIGAATPRTVADLYRRIARAGVGIPVVAHMHNTRGTALANCV
                     AALDAGCRHFDTAFGGVGGHPARIAYGQGLTGNACTEDLVALFEAMGVDTGLDPDRVAA
                     ASELCERALGRELYSMVAKGRKEKLDA"
     gene            complement(15274..15726)
                     /locus_tag="HUW46_RS47820"
                     /old_locus_tag="HUW46_09498"
     CDS             complement(15274..15726)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501633.1"
                     /locus_tag="HUW46_RS47820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09498"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_215545230.1"
                     /transl_table=11
                     /translation="MSTLLPISELLSYRMHRVANAISRSAATRYRRDFDVSLGEWRTLA
                     LLGEDSTLTLNRLAARAGLDKAQMSRVVAKLDERGLLVRESGAGRSTRLSLSRKGKSVY
                     QGLIEAANERNDAFLVCLSAAEREALDSALDKLGKLAKALESQESL"
     gene            15850..17205
                     /locus_tag="HUW46_RS47825"
                     /old_locus_tag="HUW46_09499"
     CDS             15850..17205
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501632.1"
                     /locus_tag="HUW46_RS47825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09499"
                     /product="MFS transporter"
                     /protein_id="WP_254125632.1"
                     /transl_table=11
                     /translation="MTSTSPDGPAVPRDPLYRKVALRIMPLLLGCYVVSFIDRTNVGVA
                     QVRLKADLGFSEGVYGLAVGLFFVGFILFEVPSNMLLARIGARKTLVRIMLSWGVITML
                     TALATTPALFYTARFLLGVAEAGFFPGALFYLAQWFPSARRTRMTALFFLGVPLSGIVG
                     PPLSGWIMHTLGGAFGLKDWQWLFVLEALPPILLGLLVLRFFQDKPAEARWLGEDERRA
                     IAADLAADQDRKQAGAKHGGMLRALKDPRVYVLGLVSCGCYTLANAVSFWTPLVINSSG
                     VGNVLDIGLLAAIPPVLGMGVMLLVGRHSDRTMERRWHAAGAEFFAAACLVGLSFVSGD
                     PYLVLVLLALMTAAHYSGLTVFYSIPSIYLSGPAAASGIAMVTTMGSLAAATSPALLGW
                     IKTTTGSLDLGLQISAGVVVLGGIILLVGIPARALREGTGAAVGAARSQVRG"
     gene            complement(17349..18989)
                     /locus_tag="HUW46_RS47830"
                     /old_locus_tag="HUW46_09500"
     CDS             complement(17349..18989)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636768.1"
                     /locus_tag="HUW46_RS47830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09500"
                     /product="amidohydrolase"
                     /protein_id="WP_215545231.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1e-07, bitscore:
                     30.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGDLVLRGGLVRTFDGERTVSALLVRDGLVRTVGDDSTVSAAAG
                     ADARIVELRGKTVVPGLNDAHLHLAWHALSGPEYCVDLAAAGDLAAVGTALASAPDGEW
                     IVGRGWRETTVAEFAAGEAVPSRAWLDEVTGDRPAVLHHASSHSVWANSAALRLAGITA
                     ATPDPPAGEIVRDEHGEPTGLLVESAQDLVARLIPKPGKEERLDTIERGMRRLNRLGVT
                     SATDPIVPPELWRDYRDLHAAGRMTVRVTALLHWDWPNPTTSAANLRRALDGATFGGDD
                     LLRAGGIKLFADGVPTHCTAWMHRPYPDGGHGDLVTLGESVESRVDELRQLVLAAQRKR
                     VRVQVHVTGDRAADAVVDAIEAAAAADPWPGARHVLIHGTFLSPAVHERLARLGIGVIT
                     SSLMRTFSGPSMVRTVGETQWAQAFPARALLDNGVPAADSSDAPVTTPDWRRGVATFTG
                     VPGPNPYGPPAPADRLSREEALRLWTTGPAWMENAESRKGTLVPGRLADFAVLDTDPVT
                     ASHEDLLTLRSVLTVLGGRVVHESEVDIR"
     gene            complement(18986..20011)
                     /locus_tag="HUW46_RS47835"
                     /old_locus_tag="HUW46_09501"
     CDS             complement(18986..20011)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501630.1"
                     /locus_tag="HUW46_RS47835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09501"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_215545232.1"
                     /transl_table=11
                     /translation="MTDRPRGITTAHVTKEYPGIGRPAVDDVSLDIADGEFMTFLGPSG
                     SGKTTMLSMIAGFTPLTAGSIAVDGHEISRLKPHRRDLGVVFQQYALFPHLTVARNVAF
                     GLARRRRPRAEIERRVADALEMVGLSALGDRFPRQLSGGQQQRVALARAVVYEPRALLM
                     DEPLGALDKKLRDQLQREIARMHRQLGMTFLFVTHDQQEALTLSDRITVFNDGRVEQVG
                     TPEDLYERPRTLFVARFIGESNALRLTPGEVTIVRPERVTLCSGTEVPPGYQRVRAEVT
                     DVVYVGDHSRVWLRYGDDTRGCAVLPAGAVHEHRPGADVVVAWHPDHQAVVPDLAESLA
                     S"
     gene            complement(20001..20819)
                     /locus_tag="HUW46_RS47840"
                     /old_locus_tag="HUW46_09502"
     CDS             complement(20001..20819)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157481.1"
                     /locus_tag="HUW46_RS47840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09502"
                     /product="ABC transporter permease"
                     /protein_id="WP_215545233.1"
                     /transl_table=11
                     /translation="MADSVTRVARKERTLGAGLRIWVALVGFVLIAPTLVVIPMSFGAG
                     STFQFPPEGWSLRWYGEFFGSKQWLGSLANSVQIGLLAAALATVLGVAAAFGLDRARFR
                     GRGAVRQVLMAPMILPGIIVAVAVYGVFLRWQLNGTMLGFVLAHTVLGVPFVLTSVQTS
                     LAGYDPTMERAAASLGANRFTTLRMVILPLVAPGVASGFVFAFATSFDEVVIALFLQTP
                     DVKTLPVKMYESIVLEIDPTIAAASSLIVVFTTVLLLVPQMLRRRSDHDR"
     gene            complement(20812..21675)
                     /locus_tag="HUW46_RS47845"
                     /old_locus_tag="HUW46_09503"
     CDS             complement(20812..21675)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157482.1"
                     /locus_tag="HUW46_RS47845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09503"
                     /product="ABC transporter permease"
                     /protein_id="WP_215545234.1"
                     /transl_table=11
                     /translation="MTAAVPGRAVRRFAAPWLLFPAAAVLLVFFCYPLAVILWRSFAEP
                     EFGFSHYVSVLGDDVQIRVVLRTLRTALIITVATLVIAYPYAYAMSRVGRRARGLLTLL
                     VLMPFWTSVMARNFAWYVLEQRGGVLEKLFDAIGIHGVSLLGSVAGVTVAMVQVMLPFM
                     VLPLQNTMRGIDRSLLHAAGSLGARGPVAFFKVYLPLSMPGVLAGVSVVFIMSLGFYIT
                     PALLGTPQQALAAQVIGTRVNDLLDFAGAGALGAILLVLTLLVLAVISRLAAPLGTSTA
                     GGADRG"
     gene            complement(21672..22706)
                     /locus_tag="HUW46_RS47850"
                     /old_locus_tag="HUW46_09504"
     CDS             complement(21672..22706)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636764.1"
                     /locus_tag="HUW46_RS47850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09504"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_215545235.1"
                     /transl_table=11
                     /translation="MRIPALLSAATILLAAGCAVSEGGENSLVFVSYGQGAYQAGQRSA
                     VLNPYTAKTGTTVTIDGPSSMAKLKAMVEAGKVAWDVVDTEASSAAQACGTLVEPVDMG
                     PLASAFPAGTLTPCGVPDAFFGLTLMYNADVYREHPPTRLSDFFDRGRFPGRRIIYGND
                     PSVGTLEAALLADGVPKDRLYPLDVRRALAMYDRIRPELTISDTYGDQQQRMAGAQADL
                     ALIVSARAYSLLKAGATNWKVVSGVPIPVTWDVLVVPKGSRRTEQAKDLIRFASEPAQS
                     AAFAEQAGVGPANEAAKPRYAEIGRQLDIWGDDKEDLRVLSDVKWWAANRVEVVRTWSD
                     WKTG"
     gene            complement(22720..24000)
                     /locus_tag="HUW46_RS47855"
                     /old_locus_tag="HUW46_09505"
     CDS             complement(22720..24000)
                     /NRPS_PKS="Domain: Aminotran_3 (30-371). E-value: 3.5e-94.
                     Score: 307.5. Matches aSDomain:
                     nrpspksdomains_HUW46_RS47855_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157487.1"
                     /locus_tag="HUW46_RS47855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_09505"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_215545236.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.5e-94, bitscore:
                     314.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTAELSELDRRSLVHPHTVLGSPAEPLVLDRGDGALLWDTDGR
                     EYIDGTCGLWQCPVGHGRAELAAVAAEQIGRLEFFSSFGDYANAPSILLADRLLKLAPE
                     GLERVFLTNGGSEGNETAIKLARLAFHHAGSPERTVILARHGGYHGMGGGSLAATGIDG
                     LRAGFGPLLPDVEWLGKPHGIEHGENATDLLVAELERRIDEIGPHRIAAFIGEPVLGVG
                     GMVPPPEGYWPRVQEVLRRHGILLIADEIVTAFGRTGHWFGSEHFGIEPDMIVLAKGIT
                     SGYIPMGAVLIGRRVLELAEGATFLHGFTYNGHPVGSAVALANIDIIERENLLDRARVL
                     GARLRKRLDPLTKLPHVREVRGVGLMLGIEFDGVPTASVQSGCRADGVIVRASGASVVL
                     SPPLVITKEQIDTLADVLCRHVAAAAD"
     aSDomain        complement(22888..23910)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS47855_Aminotran_3.1"
                     /evalue="3.50E-94"
                     /label="HUW46_RS47855_Aminotran_3.1"
                     /locus_tag="HUW46_RS47855"
                     /protein_end="371"
                     /protein_start="30"
                     /score="307.5"
                     /tool="antismash"
                     /translation="LDRGDGALLWDTDGREYIDGTCGLWQCPVGHGRAELAAVAAEQIG
                     RLEFFSSFGDYANAPSILLADRLLKLAPEGLERVFLTNGGSEGNETAIKLARLAFHHAG
                     SPERTVILARHGGYHGMGGGSLAATGIDGLRAGFGPLLPDVEWLGKPHGIEHGENATDL
                     LVAELERRIDEIGPHRIAAFIGEPVLGVGGMVPPPEGYWPRVQEVLRRHGILLIADEIV
                     TAFGRTGHWFGSEHFGIEPDMIVLAKGITSGYIPMGAVLIGRRVLELAEGATFLHGFTY
                     NGHPVGSAVALANIDIIERENLLDRARVLGARLRKRLDPLTKLPHVREVRGVGLMLGIE
                     F"
ORIGIN
        1 acgaaaccac gagtgagttc gaatcggtgc tcgcgtactt gaaggagtca cgcggcttcg
       61 acttcaccgg ctacaagcgc agcagcctca tgcgccgcgt ccgcaggcgg atggaccagc
      121 tcggcatcga gagctacgcc gactacatcg accagctcca ggtcaactcc gaggagttcg
      181 tcgccctctt caacaccatc ctgatcaacg tgacagggtt cttccgggac cccgaggcgt
      241 gggagttcct ccgcaccgag gtcgtgcccg cgatactggc cgagcgcaac ccggaggacc
      301 cgatccgggt gtggagcgcg ggctgcgcgg gcggtcaaga ggcttacagc ctcgcgatgc
      361 tgttcgccga cgcgatcggc acggacgcgt tccggcagcg tgtgaagatc tacgccaccg
      421 atgtcgacga agaagcgctg ggccaggcgc gccacgcggc ttacaccgcg agcgaggtcg
      481 aaggactgtc cgaggcgcag ctcgaccagt acttcgagct gcagggcaac cggtactgct
      541 tccgcaagga cctgcgccgg tcggtcatct tcggccgcaa cgacctcgtg caggacgcgc
      601 cgatctcccg catcgacctg ctcgtgtgcc gcaacacgct gatgtacctc aacgccgaaa
      661 cccagacgaa gatcctcgaa cggttccact tcgcgctggc gccccgcggc ctgctcttcc
      721 tcggcaaggc ggagatgctg ctcagccacg cccggatctt cgagccgatc gacctcaagc
      781 gccgggtgtt ccgcagggcc acgaacgcac cggtcagcta caaccacttc gtctcccatt
      841 ccttcccgca gcggcgcgcc tacgacatca acgggatcga agaattgcgt gagcacgctt
      901 tttccgcgag ccccgtggca cagctcgtgg tgaccgagga cgagacgacg gcgttgatca
      961 accagcaggc cgagatcgcg ttcggactgt ccgaacgcga cgtgggcagg ccactgcgcg
     1021 atctcgacgt gtcctaccgg ccggtcgcgc tgcgcgccta cgtcgaacag gcccgcatgg
     1081 agcggcgctc gctgcggatc aaggacgtcg aatggcgccg cgccggagag accgtgtggt
     1141 acgaggtgca cgtgaacccg ttgctgggca aggacaagaa gctcctcggc gtgtccgtgg
     1201 tgttccacga cgtcagctgg gcgcggcagc tgctgaccga actggagcac accaaccggc
     1261 agctggaatc ggcctacgag gaactccagt ccaccaacga agaactcgaa accaccaacg
     1321 aggaactcca gtccacggtc gaggagctgg agacgaccaa cgaggaactc cagtccacga
     1381 acgaggaact ggagaccatg aacgaggagc tgcagtccac caacgacgaa ctgcagacca
     1441 tcaacgacgc cctgcgcgaa cgcagcgtcg acctcgacga ggtgaacgac ttcctcgagt
     1501 ccgtgatgac ctcgatcaag gcgggcatca tcgtcctcga caccgagatg cgggtgaagg
     1561 cgtggaaccg cggtgccgaa gacctgtggg ggttgcggcg cgacgaagcc gagggcacgc
     1621 acctgctcaa cctcgacatc gggctgccga tgaccgacct gcgccccgcg gtgctcgaag
     1681 cgctcgccga cgcgggcttc cacagcacca ccaccgtgga agcgatcaac cgccgcggac
     1741 gcaaggcggt cgtccgcatc cagtgcgggg cgctgcacgg cgccggcggc gaaagccacg
     1801 gcgccctgct cctgatggag gaaagcggct gacggcccgg atcgtgcgcg aaccgggtct
     1861 cctaccgcac tcgcttgccg ttcgcgtcgt agcactcgca cctgtgactc aggtgctcat
     1921 gcacatcgca gaccggaacg agcgggttcc cgggctctac catgtgccga aacccgttgc
     1981 cacgcaacca attcagcgca gccgcccggt cgctgggcga ggacgttcgc gactcataga
     2041 cgcgaaatag cttcctcgca cgctccacct cgctcatgcc cccgcaccac ccggatcact
     2101 gaccaacgcc aacccggcac accgcgcgca gaccgtcgca ttcggaccga tacccggacc
     2161 gaaaacgagg ccacacctga ctttcagcgt caccccatca cgatcacgat gcatccgcag
     2221 caacaaatgc cgacgaccat cgtcgcaacg cacccacacc atcgccgtca cacccacacc
     2281 tcgcctggcg cgaggagcac ggtgtaccgg ttccgctgta tccaccgggc gcacttcggg
     2341 cacgtgccga tgagcgcggc cggtgccgga atgcgcttgg cggagatctg cgaacgcgga
     2401 tggaagtcgt ggtacggcga cacgtgcgcc ggaggctgaa ggaggttgac cgcctcgtcc
     2461 tccaactccc ccacccgata caggtgcgga aggcaatcac ccgcgaacca ccgggtcgcc
     2521 acacgaaggc tcggcggcgt gttcgtactg ctgtctgtca cgtcgcggac ggtaataacc
     2581 gctgatcatg ggacgtgtcc tagcgggaca cactccaggc acttcaccca gtcggggcaa
     2641 cacccagccg ccaagccaga cctcgcagct cccggccttc atccgagtca cgccggacgc
     2701 ggtgaagctg gttcgacact atttctcgga caaacacatt cgtccgaatc ttctgaggcg
     2761 tcaactgttc cgccttgagc aacgcagata tgccgcgcgc ccgcgaagac ttctcgggaa
     2821 gcaaagcgcg cccgaggtca gaccaaaatg cggcctgccg atgtgccact cgaagtggct
     2881 gcggcgggcg tccccgctgc gccagctcag caaccttggg gccgtacccg agttcgacac
     2941 cgatcgaaac ccgccagatg tcgacattgg tccgggtgaa gtccgtccgc gtccaggggc
     3001 gatcatcagt gtctatgatc gcggcaagtt ccgcggcctc acccaggcgc cccagagctg
     3061 tatcctcatc tccaaccact gcggatgcca tcgctgccgt gagattcgcc atgcctcgaa
     3121 ggtgctttgg tacctgcatg tcatcagcga tagccgatgc cagttcccgt tgccggaacc
     3181 tgttgcggcc gccgatgatc tgcgcccgcc gccatgccac atcagcaata gcttcagcgt
     3241 cttcgagttc ttccgctgct tgtcgcatac gttcgacagc aagagagggg actccgggaa
     3301 tgccgagatc gagcgagaca tacgcaatcg atttataggt tccgatcaag ccgagcaaag
     3361 caggcctgcg ataggtctgg tccgccgcca gtgcgagaag ctccgggatc agcttcggca
     3421 gcaaggtcgc ttgtgccaag taatccgcgt tggggcgcag aaccttattg agcaggtcga
     3481 tctctgatgc aatttcacgc cagggacgga ctgcagcgtc tggtttttcg tctacccgcc
     3541 acccggtcag tgcgtcttcg acacgtccca ttccttcgcg gagctcttcg ccaagaggat
     3601 cacgagcagg gtaaggtttt cccactaaat ccgcaggtga cacccgcagt gtcagcgcga
     3661 gagaatcaag cgctccccgc ttggtgactg gtttctcgcc ccgttcgatc ttcgcgagat
     3721 agccgtaact cagccccgac aactcggcgg cggcgcgaat ggtcaacccg cgccgctccc
     3781 gcgcttcgcg gatgttccgg ccgatagtgg cgtccatcgc aggtatcacc cttcgcggaa
     3841 tcgacccctt cgcgtgcccc ccggcccgtc gaccgggggc gtttgctccg cgaggaggta
     3901 caccaccagg gtagccgtta cctgaccggg tgaaatcggc cagctcgggt ggagaaatta
     3961 ttagcgataa cacatcgctc atcaaccccc ggtcgcggtc acggtgcgac cggacgcgac
     4021 cggctccctc ggcggcacgt gaacctcctt gaaccgcaac gactgctgcc cgaactgcca
     4081 cgcgacggtg agccgggccc gtacgagcgg tgtacgggcc cggcacccgc ttatcgcacc
     4141 gcttgcgcca ccagcgtggc gattctcttc tccacggcgg gtgtcacgtc ggtgagcgcg
     4201 aagcccgccg gccacatcgg gccgtcgtcg agggccgcct ggtcgctgaa accgagcgtc
     4261 gcgtagcgcg ccttgaactt ctccgcgctc tggaagaagc agacgacctt gccgtcgagc
     4321 gcgtaggacg gcatgccgta ccacagcttc ggctccagaa ccggcgcgtg cgccgtgacg
     4381 accgcgtgga cgcgctcggc cagcacccgg tccgccggga ccatctcggc gatcttcgcg
     4441 aggacgtccc gctccgcctg cgccgccttg tcggcctggg aggcacgccg ggcggcggtc
     4501 ttcaactcct tggcgtgttc cttcatcgcg gcgcgctctt cgaccgtgaa gctgctcatg
     4561 agaatcctcc taggggtttt cggcacggtg cgtgccgtta accgtcatca tgaccattgg
     4621 gccggtggac tgtcaatggc acgatgcgtg ccgatagact cgggggcatg gccacggaac
     4681 cacggcggcg aggcgccgcc cgcaccgacg agctcctccg gacgaccatc gagctcgcca
     4741 ccgagggcgg ttacgccggg ctgagcatcg aagccgtcgc gcgccgggcg ggcgtcggga
     4801 agcacacgat ctaccggcgc tggccgtcga tggcggcgct gctgctggac gcgctcagtc
     4861 gcgtgtggac caccgacctc gactaccacg acaccggcga cgtccgcgcc gacctgcgcg
     4921 agcagttcct gcggtcggcc cccgcgctcg ccgcaccgcc gatcgggccc gtctaccgcg
     4981 cgctgatcgc ggaagcccaa gccgacgaca ccctgcgcgc cacgctgcac gaccgattcc
     5041 tccgcaccgt cgaggaacgc acgctcgcgc ggatcgtccg cgcccagcga gccggggagc
     5101 tcgtggccgg tgccgacctg acgttcccgg ccgaagtcct gtgcggcacg ttgtactacc
     5161 gctacctgct gtcgacacgc ctcgccgacg agaaggccgt cgacgctttg ctggacatgt
     5221 tcatggccgc ctacgggcat tagcctgccg ctcgaccacc tgagcgtgga cggctctcgc
     5281 cgcacaccgt cacgggcggt gcgctcagac gaccttggcg tcgatcagct gctgccagat
     5341 ctcgccctgg tcgacgactt cgacctcgag cttctcggcc ttggcgagct tgctggcgcc
     5401 gacctcggcg ccggtgatca gcatgtccgt gctcgccgag accgacgaag cgatgctcgc
     5461 gcccgctttc tcgcacaggc gctggaaagt cgggcggggc accttctccc cggagcgcgg
     5521 gtcgctgatc gcgccggtga ccacgaccgt cttcccggcc agcggcgcac cggccgcgac
     5581 caccgggggc aggtcttcct cgcgcacgtc gagggaaacc ccgcgctccc gcagccgttc
     5641 cagctcgggc cgcagccggg tgaggtgctc gaccagcgag gcggcgacct tcggcccgat
     5701 gtcctccacc gccacgagcg cgtccacgcc cgcgtcggcg acctcttcca gcgacccgaa
     5761 ccccgcccgg cacaaccggg ccgcggtgcc gtcggaggcc atcgggatcg cgagcccgat
     5821 cagcgcccgg cgcaggccga ccgcgcggct ggcgtcgatc gactcgatca tgcgcgtcgc
     5881 cgacacctcg ccgacgcggt cgaactccag caaccgctcc ttggtcagcc ggtagaagtc
     5941 cgacgggtgc tccagctccc ctgcctcggc gagccgttcg atccacaccc cgccgatggc
     6001 gtcgatgtcc gccgccgccc tcgacgccca gtggatcagc cgccgcacgg tctgcgcggg
     6061 acaggacacg ttggtgcaga acaactcccg gctattgccc tgttcggtca gcggctgcgc
     6121 gcacgacggg cagtccgccg gtggcacgat ctcgacctcc gcgccggtgc gcttcgactc
     6181 gtcgagcacc ccggcgacga acgggatcac gtcacccgcg cggcgcacca gcaccgtgtc
     6241 gccgatcttg atcccgcggg cgcggatcac ctcctggttg gccagcgtcg cgcgggtgac
     6301 cgtggtcccg ccgacgaaca ccggctccag ccacgccacc ggcgcgatct tgccggtctt
     6361 cccgacgtcc cagaccacat cggacagcac ggtggtcttc tcctctgcgg cgaacttgaa
     6421 cgccagcgcg ccgcgcggcg agctcgaccg cgtgcccgcg gcggcgtagg cgtcgcgatc
     6481 ggccagccgc agcacggcgc cgtccaggtc gtagtccagc tcgttgcgcc gccgctcgat
     6541 ctcggagatc accgcctgtg ccgcttcggc gtcggcgcag tgccgcatgt cggccgcggc
     6601 gaacccgagc gtgcgcagcg caccgtccaa atcggactcc gcgctgtccg gatcggtgtg
     6661 caggtcgaag gcgaggaatt gcaggcgccg ctcggccacg gtggccgggt ccttcgcccg
     6721 cagcgtgccc gccgcggcgt tgcgcgggtt gatcagcggc ttgtccgggt gcgcggcgtt
     6781 gtaggcggcg aaggtggaac gcagcatgac cgtctcgccg cgcacctcga cccggccagg
     6841 cgcgtcgatg cgctcgggca ccccgctggt cagcacccgc accagcgggg tcacgtcgtc
     6901 accggtggtg ccgtcgccgc gggtgaccgc ccgcgccagc cgtccgtctt cgtagaccag
     6961 tgccagcgac aacccgtcca gcttcggcat caccaccacc ggctggccgg ggaaccggtc
     7021 gaagaacgcc acgacctgct cgggcttggt cgccttctcc agcgacagca tggggcgcga
     7081 gtgccgcacc ggcgcgtgca gcaccgtcgg cgcgcccacc cgctccaacg ggttcggctc
     7141 cggcgccagg tcagggttcg cctcgatcag cccgcgcagc tcgtcctcga gttcgtcgta
     7201 ctcggcgtcg gcgactttcg gcgagccgcg gtagtaggcg tcgcgcagcg ccacgacctg
     7261 atcggcgagt tcctgaatgc gtttcccagc gtccacggca cagcacgcta cccgtgccca
     7321 ccgacaggac cgggcaagtg ccgatccgcc cgcgagttcc gccgtgagcg taagcgctgc
     7381 caccgggtgc cggaggagtg ccaggatgac ggcatggcgg acatcctcga cttccaccgg
     7441 aaccgcaccc cggaccgcga gcccgacccc gagcccgaac cgctgtggcg cgaggccctc
     7501 ggcaggagcc tgcgcgggat gcgggaagac cgcggcggtc gcctcgtcga catcgcggag
     7561 cgggccggga tctcacccca gtacctgtcc gagatcgaac gcggtctcaa ggagccgtcg
     7621 agcgagatga tcgccgcggt caccggcgcg ctcgggatcg gcctgcccga cctgctcacc
     7681 gggatcgcgg gcgaggtcag gcggtaccac cacccgcgtc ccgtgcgccg cccggccggc
     7741 ccgctgctga tggcggcctg accggtcagg gccggtggtc gatgatcgtg tccgcgagcc
     7801 cgtaggcgac cgcgcccgcc gcgtcgaaca cgcggtcgcg gtcggtgtcg tgccgcaggt
     7861 ccgcgacctc gcggccggtg tgcgccgaga ggatctcctc cagctgggtg cgcacccgca
     7921 ccacctcgtc ggcctgcagg atcaggtccg ggatggtgcc gcggccctgc gccgcgggct
     7981 ggtgcagcac caccctggtg tggggcagca ccgagcggtg ccccgactcc cccgcggcca
     8041 gcagcaccgc gctcgccgcg acggcctgcc cgacgcacgt cgtcgccacc ggcgccttga
     8101 tgaaccgcat cgtgtcgtac agcgcgagca tcgcggacgg gtcgccgccc tcggagttga
     8161 tgtacaggtt gatgtgctgg tccggatcgt ccgcctccag gtgcagcaac tgggcgatca
     8221 gggcgttcgc caccccggag tcgatcgcgg tgccgaggta gacgatccgc gacgacagca
     8281 ggtgcgagta gacgtccatg acccgctcgc cgcgcacgtc ccgcgtgatg acgttgggaa
     8341 tcgtgtaggt gctcacgcgc gcgctcccgc cgccgtgccg agtccgagcc ggtgcgtgcg
     8401 cacgggcacc acctggtcca gcgagtcgac gatgtggtcg atgaagccgt attcgcgcgc
     8461 ctgcccggtg gtgaaccagc ggtcgtgcag cgagtcggcg aagatcttct cgacgggctg
     8521 gccggtgtcc tcggcgatga ggcccagcac ggtgtccctg gtgtgccgca ggtcgtccgc
     8581 ctgcacctcc acctcgaccg ccgaaccgct gatccccgcc gaaccctggt gcatcaggat
     8641 gcgcgcgtgc ggcagggcga agcgcttccc gggagtgccc gcggaaagca ggaactgccc
     8701 cgcgctgcac gccagcccca acgtcaccgt gaccacgtcg cacggcacga gccgcatcac
     8761 gtcgcggatg gccagcatcg cgggcaccga cccgccggga gaatggatcc acagcgcgat
     8821 gtccttgcgc tggtcttcgc tcgcgagcgc gagcagctgg gtggcgagca cggtcccgtt
     8881 gtcgtcgtcg agcgtgccgt cgaggaccag cacgcgctgg ctgtagaacc gttcccgcag
     8941 ctgccggtcg aagaggggct gcttgtcgtc gttcgtcatg ccacgaccat gcctcccgca
     9001 cgggcgggtt cgccgctttc tccgctgtga gcggatcagc tctcagcagc gtccgtccac
     9061 tgtggaagcg cgcgaacggt ggccaggtac tcggcggcga gcgcgcgcac gatctcggcc
     9121 gcgggaagca cttcgtcgac gaggcccgcg ctttggcccg cttcgatctt gccgttgtcg
     9181 atgtcgccgt cgaacgcggc catcttcaag gtggactcgg cgaatcggac ccggcggtcc
     9241 tcgacgctcg cgccgtcgcg ttcgagcttc gccatctcgc gggtgaacgt gttgggcagc
     9301 gcgcggatga cacccagttc cctgcccagc ggctgggcgt cggacaccga cgcggacagc
     9361 accgcgcgct ggtacgcggg atggacgttc gcctcggcgc tggccaggaa cctcgtgccg
     9421 aactgcgccg cgccggcacc gagcgcgagc gccgcggcca atcccgcccc gtcggcgaaa
     9481 ccaccggacg cgatgagcgg cagccccggt accgcgcggg cgacggcacg gacgatcacc
     9541 agcgtggaca ccagatccgg cggcgggtgc ccgcccgctt cggcgccgac cacgaccagg
     9601 ccgtccactc cggcatcggc cgccttgcgc gcgtgctcgg cgctcgcgac gacgtgcagg
     9661 cacacggtgc ccgcggcgcg gaaccggtcg aggtagcgcc gcggcccgcc ctgcgaggcg
     9721 atcaggaccg ggatccgttc cgccaccaac aggtccatcg cctcctcggc gcccttgcgg
     9781 tagagcggga ggttgaccgc gaacgggtgg tcggtgcccg cgcgcagcgc ccgcaccgcg
     9841 tcgcggaggt cgcccggccg catcggcccg gcggcgagca cgccgaggcc gcccgcgcgg
     9901 gacaccgcca gcggcagctc cggcgcggac gaggcccagg acatcccggc ctgcacgatc
     9961 ggaaggtcga tgccgagcag ccgcgtgacg tccgtggcga tcatcgggcg tccaggagcc
    10021 gcacggcgtg ctcggcgagc tgcttcttct ggatcttcgc gctcgcggtc atcccgatcc
    10081 cttcgaaccc atcgacgatc cgcaggtggt gcgggacctt gaagcccgcc atctcgccac
    10141 ggcaccagtc gagcaactcc cccggcgaag gatccgcgct gccgttgagg accacgaagg
    10201 cgaacgggac ttccacgagc cgttcgtccg gcacgccgac caccgcggcc tggcggatcg
    10261 ccggatggcg gtgcagcacg gcttcgacct cggttggcgc gacgttctcg ccgccgaccc
    10321 tgatgagttc cttggccctg ccggtgaaca gcaggcgccc gtcggcgcgc aggacgccga
    10381 gatcgccggt ggacagccag ccgtcgtcgt cgagcacggc cgcggtctgc tccggcatcg
    10441 cgtagtagcc gcgcatcacg ttccacccgc gaaccaggat ttcgccctgc tgccccggtt
    10501 ccgcgtcggc accggtgacc aggtcgcgca cgcgcacgga caccccgggc tccggcggca
    10561 tgctgccgtc cacccgcagg cgctcgtcct cccaccacgc cgactgcgcg acgttgggcg
    10621 atgcctccga caacccgtag ccgaccacgg tttccgcggc gccgagttcg tcgatcacgc
    10681 gccgcaccac cgtcggcgac gccgcgagcc aggcgccgcg gaggctgagg cggtactcgt
    10741 cgcggtccgg gtggttgagc agcatcaggg cgatggtgtc gttcccggcg aagtgcgtgc
    10801 accgctcgtc ggcgagcagg cgcaacgcgg tctcgggcac gaaccgctcc gcggtgacca
    10861 aagtggacag ttgctggata caggccagta tggacagtgt cgtgcccgcg acgtggaaga
    10921 acgggcgccc gctgtagaac cggtcgcccg cgtgcaaccc gagcctggtg ccggagaaga
    10981 acgcgtcggc gcacatgttc cggtgcgtga gcagcacgcc cttggggaac gaggtggtgc
    11041 ccgaggtgaa ctggacgagc gcgacatcgt cggggtcgct gcacgcctcg accggctcgc
    11101 ccgcgcccga ggtgaactcg tcccagccga gcgcgcccgc gggcacgtcc tcgccgagca
    11161 cgacgacccg cgccagccgg ggcaggttcg ggtcgggcag ctccttttcc accgcggggc
    11221 agatttcccg cagcatcgcg gtgaactccg agctgagcac cttctccgcc aggaacagca
    11281 gcttgacgtc cgactggcgt agcgcgtact ccagttccgg cgccttgaag cgggtgttca
    11341 ccggcacggt caccgcgccg agcgaggtga cggcgaggaa cagcgcgacc cagcggggac
    11401 cgttgccgag gcagagtccg atgtggtcac cgcgttcgac gcccacgcgg tgcagcgcgg
    11461 aacgcagggc tgccacctgc tcggccagtt cggcgtaggt gacgcgttcg tgcgcgtgga
    11521 ccacggcctc gacctcgggc accacggccg ccgcgcggcg cagcgcttcg tccgtcgtga
    11581 gtggacagac gccggtcagg tccagtgctt ccaggtccat cgcgctcact ccccgctccg
    11641 atccgcgaac tcggccacgc cccgccgcca gccgccgtcg gcgaggttcc gctcgatcgc
    11701 ggcgagttcg atgcggatgc cggtggtcag cgccgcctcc tcgccgagat cgaccgactg
    11761 cttggtcagg ctcagcgcga gcggcggcgc ggccacgatc gcctcgaccg tctccgccac
    11821 cagtctctcc agttccccgg ccgccgcaag ccgggtcacc aggccgagcc gggtggcttc
    11881 gacggcgtcc acgacccggc cggtgaacag gatttccttc gcgcgccgct tgccgatgac
    11941 ccgctgcagc cgttgcgtgg cgccgaccgt gccccaatgt ggttcgggga agcggaaggt
    12001 cgccgcctcg gaggcgagca cgaagtcgca gctcatcgcg atctcgccgc cggagccgac
    12061 cacgggtccg tccaccacgg cgagcaccgg cttcccgcag cgttcgatcg tttcgtaggc
    12121 ggcgaacgag gcgagcctgc gacggcggac ccaggtctcg tccttttcct tgcgctcctt
    12181 gagatccgcg cccgcgcaga agaccgggcc gtccgccttg agcacgaccg cgcgcacgcc
    12241 gtcgtcggcg tcgaggtcgg cgaagatctc gcgcaacgcc gtgcacatcg ggaggttcag
    12301 cgcgttgcgc gcctccgggc ggttcagggt cacctcggcg acccccgcct cctcgcgcac
    12361 cagcaccggg tccacttcag atcacctctt cctcgcgcag cgccgtgatt tccgttgtgg
    12421 acagacccag gtacgaagcc agcaccgcgc cggtgtcggc gccgagccgc ggcggcacgg
    12481 cgggttccgg gtcttcgtac ccggccatcc gcaacggggt gcgcaacgcc gggaagcgcc
    12541 cctcggcggg gtggtcgaag tgcccgacca tgccgcgcgc cacggtgttc gggtcgtcga
    12601 gggcctcgcg gacggagttg acctcgccga ccgggacgtc gcggtcgcgc agcgcacggg
    12661 cgaggtcggc ccgcggccgc tgcgcgaagg ccgcgcggag cgctccgagg actcgctccc
    12721 gctggccgag acgtccggcg ttcgcggaca ggtcgggatc ggccagcaga tcggtgaggc
    12781 cgagcacctc gcacagcggg cgccagtgct gatcgcttgc gctgaggtgg agccaccggc
    12841 cgtcgcggca ctggaacgcc gccgagggca cccggcccgg atgctgcgtg ccctgccgca
    12901 cgggatcctc gccgtaggcg aacaccctgg ccgcggccag cgccagcagg ctcacctgga
    12961 cgtccatcat cgccacgtcc acatgggacc ctcgccccga cgtgccgcgc ccgacgagcc
    13021 cggtgagcac ggcgatcgcc gtccacagcc cggaagcgag gtcggagatc gggacgcccg
    13081 ccttcgcggg cggggtgtcc gggtgcccgg tcaggtgcat gatcccggac agggcttgga
    13141 agatcgtgtc gtagcccttg cggtcgcggt agggcccgtc ctgcccgaac ccggtgttcg
    13201 acacgtacac cagccccggg ttcacagtgg acagtgcctc gtagccgagc cccatcccgt
    13261 ccagtgtgcc gggcaggaag ttctccacca ccacgtcggc cttggcggcg agatcgcggg
    13321 cgatccccct accccgctcg gatttcaggt cgagcgtgat cgagcgcttc ccccggttga
    13381 acgcgaagaa gtacgcgctc tcccccgcgg gcaggcgggg ttcccagccg cgcgactcgt
    13441 cgccgcgacc gggacgctcc actttgagca cggtggcacc gagttcggcg aggcactggg
    13501 tggccagcgg cgcggccagc acccgggaga agtcgagaac ggtgatgccc gacaacggtt
    13561 tcatcggcgc tcccggaacc cgcgcatgat cacgttgacg tcccggcccg cccgcatcgc
    13621 ctcggcgtag ggcagatcag cgacccggtg gaagagcgtc ttcgtcgcgg ccatcgccag
    13681 cgggctggct tcggcccacc ggtgggcgat ccgcaggccc tcgccgagca ggtcgcccgg
    13741 ttcggcgacg cggttggcca ggccgaggtc gagcatctcc gccgcggtca gcatccggcc
    13801 gaggctgatc agctcgaagg ccagcttggg cccgagctgg cgctgcaggc cggtcatcac
    13861 caccgcgggg acgatcgagt gcttcatctc cgggtagccg aacttcacgt cggccgccac
    13921 cacggtcatg tcggcgccga tcgccagtcc cgctcccccg ccgaccgccg cgccctgcac
    13981 gacggagacc accggggtgg acagctcgcg cagcagcgac tgggtccggc tggtcagctc
    14041 ggcccgcgcc agcaccgcgg cggggttgtc cggggtcaaa tgcccgaact ccgacaggtc
    14101 cgcgccggcg cagaacccgc gcccgctccc ggccagcacc agcgcgcgga ccccctcgtc
    14161 gcggtcggct tcgagcagcg cgtcgtgcaa tgccgtggtg agcgcggtgt tcagcgcgtt
    14221 gagcttctcg gggcggttga gccgcagcac gcgcaccgcc ccctcgtcct cgctgagtag
    14281 gacctcaggc atcgagtttc tccttccggc ccttggccac catgctgtac agctcgcggc
    14341 ccagtgcccg ctcgcagagt tcggacgccg ccgcgacacg gtccgggtcc agtccggtgt
    14401 cgacgcccat cgcctcgaag agggcgacca ggtcctcggt gcaggcgttc ccggtgagcc
    14461 cttgcccgta ggcgatccgg gcgggatgcc cgccgacacc gccgaacgcc gtgtcgaagt
    14521 ggcggcagcc cgcgtccagc gcggcaacgc agttggcgag cgcggtcccg cgcgtgttgt
    14581 gcatatgggc caccacgggg atcccgaccc cggcccgcgc gatccgccgg tagagatcgg
    14641 cgacggtacg gggagtggcc gcgccgatcg tgtcgccgag ggtgatcagc ccggcgccga
    14701 gttcggcgaa gcggacgatg tcggcgacga ccgagccggg gtcgacggcg ccgtcgaagg
    14761 ggcagccgaa cgcgaccgac acgacgccga ccagggtgaa cctcccccgc gcgagccggg
    14821 tcatctccgc gacgttctcc cattgggcgg cgcgggtggt gcgcaggttg cgcgcggtgt
    14881 gcccttcggt cgccgaaacc aggaagctca gttcctcggc cccgcgaccg gcgtcgaggt
    14941 ccgcgatcgc gcgccgcacg gcccgcgggt tggggcaggt cgccttgtac gcgacgccct
    15001 cggccacggg aaggcccgcg agcacctcgg acgcgtcggc gaacgccggg acgtggcgcg
    15061 ggtggctgta gctcgtggct tcgatgcggc ggaaccccgc cgcggtgaac gcggcgacca
    15121 ggtcgagctt cgttccggtg ggcacgaacc cggtctcgtg ctgcaacccg tcgcgggcga
    15181 agcactcgca gatcgtcacg cggtctgcca tcgaccacct cctggggatc agtcctccca
    15241 ggagtaccgg agtggtgttg ataatgtcaa cagttagagc gactcctggc tctccaacgc
    15301 cttcgccagc ttgccgagct tgtccaacgc ggagtccagg gcctcgcgtt cggcggcgct
    15361 caggcacacc aggaacgcgt cgttgcgctc gttcgccgcc tcgatcagcc cctggtagac
    15421 ggatttcccc ttgcggctca gtgacagccg ggtgctgcgc ccggcaccgg actcgcggac
    15481 cagcaggccg cgttcgtcca gtttggccac caccctgctc atctgcgcct tgtccagccc
    15541 ggcccgcgcg gcgagccggt tcagcgtgag cgtcgaatcc tcgccgagca gggcgagtgt
    15601 ccgccattcg ccgaggctga cgtcgaagtc gcggcggtag cgggtggccg cgctgcgcga
    15661 gatcgcgttg gcgacccggt gcatccggta cgacagcagc tcggagatgg gaagcagcgt
    15721 gctcatcccg tgattctagg ccaccgttcg cggccacggc cccagcaccg gtgttgacat
    15781 tcacaacaga cggactgaga ctcgggtccg gcaccggacg tgccacccca ccgatcccgg
    15841 agtgagacag tgacgtcgac ttcacccgac ggccccgccg tcccccgcga cccgctctac
    15901 cgcaaggtcg ccctgcggat catgccgctg ctgctgggct gctacgtggt cagcttcatc
    15961 gaccggacca acgtcggggt ggcccaggtc cggctgaagg ccgacctcgg gttcagcgaa
    16021 ggcgtctacg gcctcgccgt cgggctgttc ttcgtcggct tcatcctctt cgaggtgccg
    16081 agcaacatgc tgctcgcccg catcggcgcc aggaagacgc tggtgcgcat catgctgtcg
    16141 tggggcgtga tcacgatgct gaccgcgctc gcgaccacgc ccgcgttgtt ctacacggcc
    16201 cggttcctgc tgggcgtcgc cgaagcgggc ttcttccccg gcgcgttgtt ctacctcgcg
    16261 cagtggttcc cctcggcgcg gcggacccgg atgaccgccc tgttcttcct cggggtgccg
    16321 ctgtccggga tcgtcggccc gccgctgtcg ggctggatca tgcacaccct cggcggcgcg
    16381 ttcggcctga aggactggca atggctgttc gtgctcgaag cgctgccgcc gattctcctc
    16441 ggcctgctcg tgctgcggtt cttccaggac aagcccgcgg aagcgcgctg gctcggcgag
    16501 gacgagcggc gggcgatcgc cgcggacctc gccgccgacc aggaccgcaa gcaggccggg
    16561 gctaagcacg gcgggatgct gcgggcgctg aaggacccgc gggtctacgt gctcggcctg
    16621 gtctcgtgcg gctgctacac cctcgccaac gcggtctcgt tctggacccc gctcgtgatc
    16681 aacagctccg gggtcggcaa cgtgctcgac atcggcctgc tcgcggcgat cccgccggta
    16741 ctgggcatgg gtgtcatgtt gctcgtcggc cgccattccg accggaccat ggaacggcgg
    16801 tggcacgcgg ccggtgcgga gttcttcgcc gccgcctgcc tggtgggcct gtcgttcgtg
    16861 tccggcgacc cgtatctcgt gctcgtgctg ctggcactga tgaccgcggc gcactactcg
    16921 gggctcacgg tcttctactc gatcccgtcg atctacctgt ccggccccgc cgcggcgagc
    16981 gggatcgcga tggtgaccac gatgggctcc ctcgccgcgg ccaccagccc ggcactgctc
    17041 ggctggatca agaccaccac cggctcgctc gacctcggct tgcagatcag cgcgggcgtc
    17101 gtggtgctgg gcgggatcat cctcctcgtc ggcatccccg cccgcgccct tcgggaaggc
    17161 accggtgccg ccgtcggcgc cgcccggtcg caggtgcgcg gctgaccgcg gggtgcgagg
    17221 gccgagttcg cggcgtctag ttccccgaag gccaccttcg gggcatcgcg ctctcgtaac
    17281 cggccgagcg agggggcgat tcgtgacgct caagtccccg aaggtggcct tcggggcgcc
    17341 aagtgccgtc atcgaatgtc tacttcggac tcgtggacca cgcggccgcc gaggacggtc
    17401 agtaccgagc gcagcgtcag caggtcctcg tgggacgcgg tgaccggatc ggtgtccagc
    17461 acggcgaaat ccgcgagccg tccggggacc agggtgccct tgcgcgactc ggcgttctcc
    17521 atccaggcgg gcccggtggt ccacagccgc agcgcctctt cccggctcag ccgatccgct
    17581 ggtgccggtg gcccgtaggg gttcgggccg ggcacgccgg tgaaggtggc gacgccgcgc
    17641 cgccagtcgg gcgtggtgac cggcgcgtcc gagctgtccg cggcgggcac cccgttgtcg
    17701 agcagcgccc gagccggaaa cgcttgcgcc cattgggttt caccgacggt acgcaccatc
    17761 gacggcccgc tgaaggtccg catgagcgag ctggtgatca ccccgatccc gagccgcgcc
    17821 agccgttcgt ggaccgcggg cgagaggaac gtcccgtgga tgagcacgtg ccgcgcgccc
    17881 ggccacgggt cggcggccgc cgcggcctcg atcgcgtcca ccaccgcgtc cgcggcgcgg
    17941 tcaccggtga cgtgcacctg cacccgaacc cgtttccgtt gtgccgcgag gacgagctgc
    18001 cgcagttcgt ccactctgga ctccacgctc tcccccagcg tgacgagatc gccgtggccg
    18061 ccgtccgggt acggccggtg catccacgcc gtgcagtgcg tcggcacgcc gtcggcgaac
    18121 agcttgatcc ccccggcgcg cagcaggtcg tcaccgccga acgtcgcgcc gtccagcgcg
    18181 cggcggaggt tcgcggccga ggtggtggga ttgggccagt cccagtgcag gagcgcggtc
    18241 acccgcaccg tcatccggcc cgcggcgtgc aggtcccggt agtcccgcca cagctcgggc
    18301 ggcacgatcg gatccgtcgc gctggtgacg ccgaggcggt tgaggcgccg catcccccgc
    18361 tcgatggtgt cgagccgttc ttccttgccc ggcttcggga tcagcctcgc gacgaggtcc
    18421 tgcgcgcttt cgacgagcag cccggtcggt tcgccgtgtt cgtcgcgcac gatctcgccc
    18481 gcgggcggat ccggtgtggc ggcggtgatc ccggccaggc gcagcgcagc gctgttggcc
    18541 cacaccgaat gcgacgacgc gtggtggagc acggcggggc ggtcgccggt gacctcgtcg
    18601 agccaggcgc gcgacggcac cgcctcgccc gccgcgaact ccgcgacggt cgtctcccgc
    18661 catccgcgac cgacgatcca ctcgccgtcc ggcgccgaag ccagcgcggt gccgacggcg
    18721 gcgagatcac ccgccgccgc gaggtccacg cagtactcgg gtccgctcag cgcgtgccag
    18781 gccaggtgca gatgcgcgtc gttgagaccg ggcaccaccg ttttcccgcg cagctccacg
    18841 attctggcat cagcgcccgc cgcagcggac accgtggagt catcgccgac ggtgcgcacg
    18901 agaccgtccc gaaccagcag cgcggatacc gtccgttcgc catcgaacgt acggacaagc
    18961 ccgccccgca acaccaaatc ccctttcatg acgcgagact ctcggcgaga tccggcacga
    19021 ccgcttggtg gtcgggatgc caggccacca cgacgtccgc gccgggccgg tgctcgtgga
    19081 ccgcgcccgc gggcagcacc gcgcagcccc gcgtgtcgtc gccgtagcgg agccataccc
    19141 ggctgtggtc cccgacgtag acgacatcgg tgacctcggc gcgcacgcgt tgataaccgg
    19201 gaggaacttc ggtgcccgag cacagcgtca cgcgttcggg ccgcacgatc gtcacctccc
    19261 ccggggtgag gcggagcgcg ttggactcgc cgatgaaccg cgcgacgaac agcgtccgcg
    19321 gacgctcgta gaggtcctcc ggggtgccga cctgttcgac gcgcccgtcg ttgaacaccg
    19381 tgatccggtc ggacagcgtg agcgcctcct gctggtcgtg agtcacgaac aggaacgtca
    19441 tgccgagctg gcggtgcatc cgcgcgatct cgcgctggag ctggtcgcgg agcttcttgt
    19501 ccagcgcgcc gagcggctcg tccatcagca gcgccctcgg ctcgtagacc acggcgcgcg
    19561 cgagcgctac ccgctgctgc tgcccgccgg agagctggcg ggggaagcgg tcaccgagcg
    19621 cggacaggcc gaccatctcc agcgcgtcgg cgacccgtcg ctcgatctcc gcgcgcggcc
    19681 gccggcgcct ggcgagtccg aacgcgacat tgcgcgccac ggtcaggtgc gggaaaagcg
    19741 cgtactgctg gaacaccacg ccgagatcgc gccgatgggg tttgaggcgc gagatctcgt
    19801 ggccgtcgac cgcgatcgac cccgcggtga gcggggtgaa cccggcgatc atggacagca
    19861 tcgtggtctt cccggacccg gacggcccga ggaaggtcat gaactcgccg tcggcgatgt
    19921 ccagcgaaac gtcgtccacg gcgggacggc cgatcccggg gtactccttg gtcacgtgcg
    19981 cggtggtgat gccgcggggt ctatcggtca tgatcgctcc ttcggcgaag catctggggc
    20041 acgagcagca ggaccgtcgt gaacaccacg atgaggctgg acgccgcggc gatggtcggg
    20101 tcgatctcca gcacgatcga ctcgtacatc ttcaccggca gcgtcttgac gtccggggtc
    20161 tgcaggaaca gggcgatgac cacctcgtcg aacgaagtgg cgaaggcgaa cacgaaaccg
    20221 gaagccactc ccggcgcgac gagcggcagg atcaccatgc gcagcgtcgt gaaccggttc
    20281 gccccgaggc tcgccgcagc ccgttccatc gtggggtcgt acccggcgag gctggtctgc
    20341 accgacgtca gcacgaacgg cacaccgagc accgtgtggg ccagcacgaa gccgagcatg
    20401 gtgccgttga gctgccaccg caggaagacc ccgtacaccg cgaccgcgac gatgatgccg
    20461 ggcaggatca tcggcgccat cagcacctgc cggacggcgc cgcggccgcg gaagcgggcg
    20521 cggtcgagcc cgaacgccgc ggcgaccccg agcacggtgg ccagcgcggc ggccagcagt
    20581 ccgatttgga cggagttggc cagcgacccc agccactgct tgctgccgaa gaactcgccg
    20641 taccagcgca gcgaccagcc ctcgggcggg aactggaacg tcgatcccgc gccgaagctc
    20701 atcgggatga ccacgagcgt cggcgcgatc agcacgaacc cgacgagcgc gacccagatc
    20761 cgcagccccg caccgagcgt gcgttccttg cgggccaccc gcgtgacgga gtcagccacg
    20821 gtccgcacct cccgccgtgc tggtgccgag cggcgcggcg agcctgctga tcaccgcgag
    20881 cacgagcagc gtgagcacga gcaggatcgc gcccagcgcg cccgcgcccg cgaagtcgag
    20941 caggtcgttg accctggtgc cgatcacctg cgcggccagc gcctgctgcg gcgtgcccag
    21001 cagggccggg gtgatgtaga agccgagcga catgatgaac accaccgaaa cgcccgcgag
    21061 gacgcccggc atcgacagcg gcaggtacac cttgaagaac gcgacgggcc cgcgtgcgcc
    21121 gaggctgccc gcggcgtgca gcaggctccg gtcgatgccc cgcatggtgt tctgcagcgg
    21181 cagcaccatg aacggcagca tcacctgcac catcgccacg gtcaccccag cgacggaacc
    21241 cagcaggctc acgccgtgga tcccgatggc gtcgaagagc ttttcgagca cgccgccccg
    21301 ttgttccagc acgtaccagg cgaagttgcg ggccatcacg ctggtccaga acggcatcag
    21361 cacgagcagc gtcagcaggc cgcgggcgcg cctgccgacg cggctcatcg cgtaggcgta
    21421 gggataggcg atgaccaggg tcgcgaccgt gatgatcagg gccgtccgca gggtgcggag
    21481 cacgacgcgg atctgcacgt cgtcgccgag cacggaaacg tagtgggaga agccgaactc
    21541 cggctcggcg aagctgcgcc agaggatcac ggcgagcggg tagcagaaga acaccagcag
    21601 gaccgccgcc gcggggaaga gcagccaggg agcggcgaag cggcggaccg ccctccccgg
    21661 caccgcggcg gtcatccggt cttccagtcc gaccaggtcc gcacgacctc gacccggttg
    21721 gccgcccacc acttcacgtc gctgagcacg cgcaggtcct ccttgtcgtc accccagatg
    21781 tccagctgcc gcccgatctc cgcgtagcgg ggcttcgccg cttcgttggc ggggcccacc
    21841 cccgcctgct cggcgaaggc ggccgactgc gccggttcgg aggcgaagcg gatcaggtcc
    21901 ttcgcctgct cggtgcggcg ggatcccttg ggcaccacca aaacgtccca ggtgaccggg
    21961 atcggcaccc cggaaaccac cttccagttg gtggcaccgg ctttcagcag cgagtaggcg
    22021 cgggcactga cgatgagcgc caggtccgcc tgcgcgccgg ccatgcgctg ctgctggtcg
    22081 ccgtaggtgt cgctgatcgt cagctcgggc cggatccggt cgtacatcgc cagcgcgcgc
    22141 cgcacgtcga gcgggtagag ccggtccttc ggcacgccgt cggcgagcag cgccgcctcc
    22201 agcgtgccga cgctcgggtc gttgccgtag atgatccgcc tgccggggaa ccggccgcgg
    22261 tcgaagaagt cggacagccg ggtcggcggg tgctcgcggt agacgtcggc gttgtacatc
    22321 agcgtcagcc cgaagaacgc gtccgggaca ccgcacggcg tcagcgtccc agccgggaac
    22381 gccgaggcga gcggccccat gtcgaccggc tcgacgagcg tgccgcacgc ctgcgccgcc
    22441 gacgaagcct cggtgtcgac gacgtcccag gcgaccttgc ccgcctcgac catcgccttg
    22501 agcttggcca tgctggacgg gccgtcgatc gtgaccgtgg tgccggtctt cgccgtgtac
    22561 gggttcagca cggcggaccg ctgcccggcc tggtaggcgc cttggccgta ggaaacgaac
    22621 acgagggagt tctcgccgcc ctcggagacg gcgcacccgg cggcgaggag gatcgtcgcc
    22681 gcggacaaca acgctggtat ccgcacgggt ccctccccct cagtccgcgg cggccgcgac
    22741 gtggcggcac aggacgtcgg cgagggtgtc gatctgctcc ttggtgatca ccagcggcgg
    22801 ggagagcacg acgctggcac ccgaagcgcg cacgatgacc ccatcggcgc ggcagccgga
    22861 ctgcacggaa gcggtaggca cgccgtcgaa ctcgatgcca agcatcaggc cgaccccgcg
    22921 cacctcccgc acgtgcggga gcttcgtcag cgggtcgagc cgcttccgga ggcgcgcgcc
    22981 caggacgcgg gcgcggtcga ggaggttctc gcgctcgatg atgtcgatgt tcgcgagcgc
    23041 gacggcggat ccgaccgggt ggccgttgta ggtgaacccg tgcaggaacg tggcgccctc
    23101 ggccagttcc agcacccggc ggccgatcag caccgcgccc atcgggatgt agccgctggt
    23161 gatgcccttc gcgagcacga tcatgtccgg ctcgatgccg aagtgctcgc tgccgaacca
    23221 gtgccctgtc cggccgaacg cggtcacgat ctcgtcggcg atgagcagga ttccgtggcg
    23281 ccgcagcact tcctggaccc gcggccagta cccctccggc ggcggcacca taccgccgac
    23341 gccgaggacg ggttccccga tgaacgcggc gatccggtgc gggccgatct cgtcgatacg
    23401 ccgctccagc tcggcgacga gaagatcggt cgcgttctcg ccgtgctcga tgccgtgcgg
    23461 cttgcccagc cattcgacgt ccggcagcag cggcccgaat cccgcgcgca gcccgtcgat
    23521 cccggtcgcg gcgagcgaac cgccgcccat gccgtggtag ccgccgtggc gggcgaggat
    23581 caccgtgcgc tccggcgaac ccgcgtgatg gaaggccagc cgcgcgagct tgatcgcggt
    23641 ctcgttgccc tcggaaccgc cgttggtgag gaagacgcgt tccagccctt cgggtgcgag
    23701 cttgagcagc cgatcggcga gcaggatcga cggggcgttg gcgtagtccc cgaacgacga
    23761 gaagaactcc agcctgccga tctgttcggc ggcgacggcg gcgagttcgg cgcgcccgtg
    23821 cccgacgggg cactgccaca gcccgcacgt gccgtcgatg tactcgcggc cgtcggtgtc
    23881 ccagagcagg gcgccgtcgc cgcggtcgag gacgagcggc tcggcgggcg agccgagcac
    23941 ggtgtgcggg tgcaccaggc tgcggcggtc caattcggac agttccgcgg tggaggtcat
    24001 cgagatcctt tcgaagagag gcgggtcagg agcacgcggt tcagaaacgc agcgcgacgg
    24061 ctttggtctc ggtgtaggcg tcgatgccct cgctgccgcc ttcgcgttcc tgcccggagt
    24121 tcttctgccc gccgaacggg agttccgggc ggaccggggc ggggtcgttc acgccgaaca
    24181 cgccgaagtc gagccggtcg agcaggcgcc agatgcggcg gagatcggag ccgaacacgt
    24241 acgcggcgag gccgtactcg gtcgcgttgg ccagctcgac gacttcctcg tcgtcggtga
    24301 acgtcgacac ggccaaggcg ggaccgaaag tctcttcgtg cgcgatcagc atcccggggg
    24361 tcacgtccac gagcacggtc ggctggaaga agtggccgcg cagcgcggga tcgcccggct
    24421 cccagcggtt tccgccgacc agcacccgcg ccccctgctc gacggcgtcg gcgacctggc
    24481 gctcgacctt cgcgatcccg gcctcgtcga tcaacggccc caccgcgacg ccctcggcgt
    24541 ccccgcgccc gagccgcagt gcggacgtct tcttctcgat cagcgccagc aggtcttcgc
    24601 ggatgccttc gtgcacgtac agccggttca ccgcggtgca gctctgcccg gcgttgaaga
    24661 acttcgccgt caccaccccg gacgcggccg cttcgagatc ggcgtcttcg aggacgatcg
    24721 ccggtgagtg gccgcccatc tccagcgagg tccggcgcag cacggaaccg gtgcggcgca
    24781 acagtcccag gccgacctcc gtcgacccgg tgaagctcac cttgcgcagc ctgcgatcgg
    24841 tgagcagggc gtccaccagc tccgcgggcc gcgacgtggt gagcgatccg agcacgcccg
    24901 cgggcaggcc ggtctcctgc aggattccga gcagtgccgt ggcgatgagg ggcgtctgct
    24961 cggcgggttt cgcgaccacc gtgcacccgg cggcgagcgc gagccccacc ttgcggatca
    25021 gcatgctagc cggaaagttc cacggcgtga tcgcgagcac cggcccgacc gggctgcgca
    25081 gtaccagtcc ggggcccgcc gcgttcgccg gggtcaccct gccgtcggcg cggcgcccct
    25141 cctccgcggc ccagtccagc atccgcgcgg caccggccag ttcccccgcc gcttccgcga
    25201 gcggtttacc g
//
