LOCUS       NZ_CP059997            24616 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9217039
            Orig. end                         :: 9241655
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24616
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="43"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24616
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24616
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14616]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14616
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            922..1323
                     /locus_tag="HUW46_RS42935"
                     /old_locus_tag="HUW46_08506"
     CDS             922..1323
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034286.1"
                     /locus_tag="HUW46_RS42935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08506"
                     /product="tautomerase family protein"
                     /protein_id="WP_215544372.1"
                     /transl_table=11
                     /translation="MPFVRIDALRADPDRLDALGRAVHDALVEAIGIPADDRFQVLTGH
                     DGARSTLRYDDGYLGVHRDDDLVFVAITMRSGRTPALKQALYRRIAELAHEYAGTEPRN
                     VFVTVTENEPIDWSFGDGIAQYAEKAPLH"
     gene            1399..2265
                     /locus_tag="HUW46_RS42940"
                     /old_locus_tag="HUW46_08507"
     CDS             1399..2265
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020502022.1"
                     /locus_tag="HUW46_RS42940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08507"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_215544373.1"
                     /transl_table=11
                     /translation="MRNNDLGEFLRARRAGLKPDEIGLPVEFGGGRRVSGLRRGEVAQL
                     AGVSAEYYTRLEQGRARQPSEQVLHALGDALRFDDIERRHLFALAGTTAGRQDRAEHSS
                     RLRPALRQVLESMELASAFVSDQNLTVVGGNALWALLFPDVAELPRRERSMARWTLLDP
                     RARLVWCDWERVARDYVHGLRLAAAAQPRNQHIANLIGELMMRSPEFPAWWSEHRVQER
                     STGLKRLHHPVVGDLELQYEIFTSVADAGQSLVVYTAPSGSPSQERLRLLASWSSEPAA
                     AKDTAES"
     gene            2364..3215
                     /locus_tag="HUW46_RS42945"
                     /old_locus_tag="HUW46_08508"
     CDS             2364..3215
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-161). E-value: 1.2e-08. Score:
                     27.0. Matches aSDomain:
                     nrpspksdomains_HUW46_RS42945_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014182462.1"
                     /locus_tag="HUW46_RS42945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08508"
                     /product="oxidoreductase"
                     /protein_id="WP_215544374.1"
                     /transl_table=11
                     /translation="MSKTFLITGVSTGLGLAIARRALAAGHRVAGTVRTEQHAAAFRAL
                     DPDRVRAFILDLSDADRIDPTVRAAEAELGPIDVLVANAGYGLEGTFEESSMAELRRQF
                     EVNVFGTVATVKAVLPGMRERRGGHIFVITSMGGHTTFPGLAFYEGSKHAMEGITDTLA
                     QEVAQFGVRVTAVAPGAFKTDWAGRSLVRAPRGIADYDALFDPIRSRRQALAGQGIGDP
                     DRAGDAILALLDVEKPPVHLLLGSDALRLVAAGRRRVQDDIDAWEELSRSTDSTEGGVT
                     VA"
     CDS_motif       2373..2447
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS42945_0001"
                     /evalue="1.90E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="HUW46_RS42945"
                     /protein_end="28"
                     /protein_start="3"
                     /score="10.9"
                     /tool="antismash"
                     /translation="TFLITGVSTGLGLAIARRALAAGHR"
     aSDomain        2373..2846
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS42945_PKS_KR.1"
                     /evalue="1.20E-08"
                     /label="HUW46_RS42945_PKS_KR.1"
                     /locus_tag="HUW46_RS42945"
                     /protein_end="161"
                     /protein_start="3"
                     /score="27.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TFLITGVSTGLGLAIARRALAAGHRVAGTVRTEQHAAAFRALDPD
                     RVRAFILDLSDADRIDPTVRAAEAELGPIDVLVANAGYGLEGTFEESSMAELRRQFEVN
                     VFGTVATVKAVLPGMRERRGGHIFVITSMGGHTTFPGLAFYEGSKHAMEGITDT"
     gene            complement(3222..4448)
                     /locus_tag="HUW46_RS42950"
                     /old_locus_tag="HUW46_08509"
     CDS             complement(3222..4448)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228768.1"
                     /locus_tag="HUW46_RS42950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08509"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_215544375.1"
                     /transl_table=11
                     /translation="MNDVEESITRAHHEEWARVVAALTRRFGDLDIAEEAAAEAFTAAV
                     EKWPADGVPPNPGAWLTTTATRRAIDRIRRETKRDDKHKEAQLVYDDDPPEPLGAIDDD
                     RLRLIFTCCHPALATEARLALTLRMVGGLTVPEIARAFLVAESALGQRITRAKAKIKAA
                     RIPYRVPSAEDLPARLTGVLTVLFLVFNEGYLATGPDTDPMRHELTAEAIRLTRLIRAL
                     LPDDGEVAGLLALMLLTEARRPARVSASGELVALDEQDRGAWDTGMIAEGHQLVRERLA
                     AGVAPGRYQILAAINAVHTSARDVRDTDWSQVLALYDQLVRLDASPVIALNRAIAVAEL
                     DGPEVALAAVDRLEHRLAGYHPYHVTRADLLRRLGRGKESRAAYDKAIELAGNTAETAY
                     LTRRRDQLG"
     gene            complement(4445..4768)
                     /locus_tag="HUW46_RS42955"
                     /old_locus_tag="HUW46_08510"
     CDS             complement(4445..4768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640379.1"
                     /locus_tag="HUW46_RS42955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08510"
                     /product="YciI family protein"
                     /protein_id="WP_215544376.1"
                     /transl_table=11
                     /translation="MQYLVSVIDDKENPGSTDRQPAISAFNERLIADGYWVFAGGLADT
                     ATATVIDNRGEQAVVTDGPFVESKEYLAGVWVWEVPDLDVALKLATEASKACDRKIEVR
                     PFQ"
     gene            complement(4806..5429)
                     /locus_tag="HUW46_RS42960"
                     /old_locus_tag="HUW46_08511"
     CDS             complement(4806..5429)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692892.1"
                     /locus_tag="HUW46_RS42960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08511"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_215544377.1"
                     /transl_table=11
                     /translation="MKLTTMAKVTIDGVVQGDGGATEEDRRNGFERGGWALGRGDADTH
                     SLIKQTFQRADAFLLGRRTYELFAASWGSWTEHHVPDWEPVRRALNTRPKYVASTTLTD
                     PAWAGTTVLSDDLAAAIAELKAKPGGELHVHGSGTLIRWLLENGLVDEMTLLVVPVILG
                     QGTRLFPETGPDLALDLIDSRVDSKGVTTQVFRPAGRPRYAPAR"
     misc_feature    5523..5536
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.75"
                     /tool="antismash"
     gene            complement(5567..5947)
                     /locus_tag="HUW46_RS42965"
                     /old_locus_tag="HUW46_08512"
     CDS             complement(5567..5947)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="HUW46_RS42965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08512"
                     /product="VOC family protein"
                     /protein_id="WP_215544378.1"
                     /transl_table=11
                     /translation="MHIGPVIAVTDLDRAREFYEEKLGLAGEEAPGGWLLRGSEGTVIY
                     LLASVSDAGSPSWPVASIRVDDANETVRTLRSRGVPFLGKDDLPFALDEDGVSADTSGI
                     RVAWMRDPDGSVLTIFSRTPAA"
     gene            complement(5947..7242)
                     /locus_tag="HUW46_RS42970"
                     /old_locus_tag="HUW46_08513"
     CDS             complement(5947..7242)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151250.1"
                     /locus_tag="HUW46_RS42970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08513"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_215544379.1"
                     /transl_table=11
                     /translation="MTERATSGATEAAGYPAKTGRALAADVDLWPGVDDPAALLGHITD
                     WLAGYGNHATRRTYAEGLGLPTRPSDIDAWEQPSRGGEWTSVLARYQDVLRIDATESRA
                     KRPGPPPAAPGRLRRWHWFRWCAATGVDPRAATSRHVKSWLDALAGADAAPATRDRMLA
                     TVKALYAYLAEIGVVTANPAALNRRRLGLTAAAAGTSRTVTLTSAQVRALYATAAQRRP
                     GASALDTHRAVAVIALFTLGLRVSELCGLDRADLHVTRGRRALRVHGKGGKDRIVYLSG
                     PADTALTRYLVLRDDTGKATGAAVTRRQRGTRADTTPLLLTRTGRRFQRQAIWQLLRRV
                     AAAGGEELTAIAGALHPHALRHFYVTTAVEAGAQLTHVQADVGHSSIDTTQQTYDHAAR
                     DPARSAVDLVADTWHGTEEPIPSDASRTGGKH"
     misc_feature    7321..7335
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    complement(7323..7336)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.03"
                     /tool="antismash"
     misc_feature    7323..7337
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.76"
                     /tool="antismash"
     misc_feature    7327..7340
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.46"
                     /tool="antismash"
     misc_feature    7327..7342
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    7349..7364
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            7385..8461
                     /locus_tag="HUW46_RS42975"
                     /old_locus_tag="HUW46_08514"
     CDS             7385..8461
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS42975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_08514"
                     /product="response regulator receiver protein"
                     /protein_id="WP_215544380.1"
                     /transl_table=11
                     /translation="MLETTTTEPSERALCAFRRCRQPLPPPGPKGGRPVEFCPDRSWQG
                     GKSCKQLAAADQALREAFGDSAPQAALQDATAAFADLADGLAAPLSELQRSLETVSASA
                     RDEVAASLTRATAADERAAEADGHRQAAEDRARQAEDDARAARDEAQEHQRARENAERA
                     EQAARADAKKAELHQARAEASAAATAEHARAAAEEARTERAKGEKLAAQLAERTEQLGV
                     ATAERDAVQDALDRERTRAVDAQQQLVARLDRAAADLDAERDHARELEQQLRDAVHQSR
                     TDAATASAALTSAQEQTRELAAELTEHRRQAATVLADRDDALARLARVHRIALDTTAED
                     LRTDLLAELLALPATPPE"
     gene            complement(8488..8712)
                     /locus_tag="HUW46_RS48660"
     CDS             complement(8488..8712)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS48660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_254126729.1"
                     /transl_table=11
                     /translation="MVPTVIATPACATGNPTTCVAYTNDSGRNNPDPKLSTLSATINAA
                     RLRAISPERIVIGDQDAIPTGDGTPFPKN"
     gene            8645..9775
                     /locus_tag="HUW46_RS42980"
                     /old_locus_tag="HUW46_08515"
     CDS             8645..9775
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="HUW46_RS42980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08515"
                     /product="MFS transporter"
                     /protein_id="WP_254126708.1"
                     /transl_table=11
                     /translation="MYATQVVGLPVAQAGVAMTVGTMAGLVVPAVSAAIVDRVGARAVV
                     VAGQLVQLAGSVTYLLAHGVVLVAVGAAMRSAGLQLFYSSMFTLITEVAGDRSTDRTFT
                     VVGAVRGAAFGIGALAVGALLTGLGPTAYTLAIGIDATTYVVAAVLLLCWLPTPAPRRA
                     AMDAATREVRPRASRVLRDPPYLGLIVVTTLFALDTDFFLVGFPVYAFDILHTPAWVPG
                     AALALLTALGSAAATLALRMTRRLSRTTAMVFAAVIVVGWCLAGAAALVLPAGVRPAYL
                     LGCTLLLVAANLVRAGRVNALAESAAPPEAKGRYLAAFQYAFTIAGVLAPAVVALFAVA
                     AWLPWMVIAAGAVLGIPLLHWITRHLHTGCAEPRPA"
     gene            10001..11701
                     /locus_tag="HUW46_RS42985"
                     /old_locus_tag="HUW46_08516"
     CDS             10001..11701
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="HUW46_RS42985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08516"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_215544382.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.6e-27, bitscore:
                     96.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRKQLTIHAEGQRRLALLGTTTATCHDLGRVCDRSRDIADLARV
                     SNRFAGAYHVVGSFDGRVYAQGSASGMHRVYHVVMDGIRVIGDRMDVLAELGSLPVDDT
                     AVAMRLVRGLPHPLSDVPLWSGVSAVAAHDCLMVETDGRGWATRTWWRRPPPELSRAEG
                     AAELRSALAEAVRARTADGLVTCDLSGGLDSTPVCYFAARSPSGVIVKTSYNNDPGGRQ
                     DLLWARRALPVMPGVRDHVVESTDTMPDFYGGLLEVIDRVDEPTQSLFCAPRIGHQLRY
                     DASHGVRTHLNGLGGDQVLCGSASWDHALFARKPLPAWRRARALHVTDGHSPWATLRAL
                     CDRSDYRAWSARIIRNAAAAAPGGTRAMLCGWALAPRFPSWLSAAAKDMLSEAMLRTMR
                     DADPIGADRAEHHELSEIRDAARMVRGSAQLGARFGVSHEAPLLDDRVVEACLAVRREE
                     RVTPVEWKPLMKAAMRGLLPDAFLRRVTKTGGGEQLMRGFRAHRRDVLTLCESSGLDES
                     GWIDMAEFTAAATPTELELPDTSLNEAVNLALFIRGSLDVSRNIQWNSR"
     gene            complement(11715..13235)
                     /locus_tag="HUW46_RS42990"
                     /old_locus_tag="HUW46_08517"
     CDS             complement(11715..13235)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672813.1"
                     /locus_tag="HUW46_RS42990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08517"
                     /product="carboxylesterase family protein"
                     /protein_id="WP_215550452.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.3e-05, bitscore:
                     23.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQPKVRTTEGVVQGLWRHRHAVFRGIPYAQPPVGALRFAAPAP
                     PHRWEGTRQAVEFGPVVPLSLPIDVPPQGDDWLTLNVGTPDPGAAGLPVLVWIPVGGYL
                     SAASSDPMYDPAALAEAGVVVVTINCRVGAEGFAFLDDVPPNRGFLDQIAALEWVQRNI
                     AAFGGDPGRVTVGGVSAGAGSVAALLTMKSARGLFRRAIAHSVPGLHSTPALARQVSTA
                     FADRLGAAAPTAEALRDIDPWHLAAELTSFNAGLHAHRESWGRLTETGTALCPVVDGEV
                     LPETPWPALTGARASGTELLVGHTRDEFRYFSVMSGRHGTFTEEDAHAVLELLAPRPGG
                     ARAYRAAFGQAGPEELVETVYSDALFRMPSQKLAEANAAAGGTSYLFELCWVAPALGGI
                     LGACHSLDVPLAFGTLNSPVGTQLIGEDPTPEAVALSRELQEAWVRFVTTGDAGWSAHR
                     PGGYLTRVLDTESKTLPYPEQASRQIWEGHSPVPFDLSETPSSPRRLG"
     misc_feature    complement(13279..13297)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.98"
                     /tool="antismash"
     gene            13333..13932
                     /locus_tag="HUW46_RS42995"
                     /old_locus_tag="HUW46_08518"
     CDS             13333..13932
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151314.1"
                     /locus_tag="HUW46_RS42995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08518"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215544383.1"
                     /transl_table=11
                     /translation="MPKQVDHRGRREAIARALWRVVEQRGVAQLTMRVVAQEAGMSLGQ
                     LQHYFASRTAMLSFAMDFASEQTSARVRQGLEKLGDRPHPRDVLRLALAEMLPLHAEAR
                     ATSRMSAAYVLEALHDEVVHEQARRGFVQGRALVEQLVRQAIADGHIDSGRDPATETNL
                     LLALTGFTPLIELDVIEPQDALAAIDVQLDRLFRST"
     gene            complement(13919..14362)
                     /locus_tag="HUW46_RS43000"
                     /old_locus_tag="HUW46_08519"
     CDS             complement(13919..14362)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="HUW46_RS43000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08519"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_254125526.1"
                     /sec_met_domain="PF13471 (E-value: 1.2e-23, bitscore: 82.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQVLPEIPTRTGLGGEIVMALALVSARILSRQSPRRLRRVLGRV
                     AAGTRPASYAQAALARDQILTFSPRCRAGNTCLPRSIAVLLVCRARGIWPTLCVGVIAT
                     PPFRAHAWIEVDEQVVGEPVDSAFYRKFFSVPCGGSDGQVRYF"
     gene            complement(14359..14616)
                     /locus_tag="HUW46_RS43005"
                     /old_locus_tag="HUW46_08520"
     CDS             complement(14359..14616)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="HUW46_RS43005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08520"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_215544384.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-19,
                     bitscore: 69.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-13, bitscore: 50.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNRALKGNVSQADTEYGRVLLDEVKSRYWHVNPTAALVLDVLGA
                     GGTAEEAARRIVHRFEIDEKTALADVRDTIDTLRERGLLA"
     aSDomain        complement(14365..14607)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HUW46_RS43005_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.40E-22"
                     /identifier="RREFam002.1"
                     /label="HUW46_RS43005"
                     /locus_tag="HUW46_RS43005"
                     /protein_end="84"
                     /protein_start="3"
                     /score="69.2"
                     /tool="antismash"
                     /translation="RALKGNVSQADTEYGRVLLDEVKSRYWHVNPTAALVLDVLGAGGT
                     AEEAARRIVHRFEIDEKTALADVRDTIDTLRERGLL"
     gene            complement(14715..14888)
                     /locus_tag="HUW46_RS43010"
                     /old_locus_tag="HUW46_08521"
     CDS             complement(14715..14888)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="HUW46_RS43010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08521"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_215544385.1"
                     /transl_table=11
                     /translation="MRPYVDREVKMDVEVVRVKQPYEAPAVVELGSFATETALNTWGNI
                     SEVQYPYVFSLP"
     CDS_motif       complement(14775..14888)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence:
                     MRPYVDREVKMDVEVVRVKQPYEAPAVVELGSFATETA"
                     /locus_tag="HUW46_RS43010_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(14715..14774)
                     /prepeptide="core"
                     /locus_tag="HUW46_RS43010_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="5.90"
                     /molecular_weight="2209.4"
                     /monoisotopic_mass="2208.1"
                     /core_sequence="LNTWGNISEVQYPYVFSLP"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MRPYVDREVKMDVEVVRVKQPYEAPAVVELGSFATETA"
                     /leader_location="[14774:14888](-)"
     gene            14982..15770
                     /locus_tag="HUW46_RS43015"
                     /old_locus_tag="HUW46_08522"
     CDS             14982..15770
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672773.1"
                     /locus_tag="HUW46_RS43015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08522"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_215544386.1"
                     /transl_table=11
                     /translation="MDLLPHLRREVHAFESVARAAADGGDAPVVPSCPEWTVSDLVAHL
                     GWVHRYVTHLVANHLLEPPDEADPSFVGLPDDRTGWPSLDGTPSEGPVLPTLLDWFTEG
                     IGALESAFHGAAHDERVWSWAEDQTAGFWLRTQAIEAAVHRWDIENAVTAAQPIDAALA
                     ADAIRHNFEVMVPKRRHDAPSEPGRGERYRFRATDREEAWTVRFDPGGVAFTDGHADVE
                     LAATTSDLMLFLWHRIPADRLTATGDQAVLDRYFALVPPA"
     gene            15905..16855
                     /locus_tag="HUW46_RS43020"
                     /old_locus_tag="HUW46_08523"
     CDS             15905..16855
                     /NRPS_PKS="Domain: PKS_ER (20-312). E-value: 1.4e-40.
                     Score: 131.3. Matches aSDomain:
                     nrpspksdomains_HUW46_RS43020_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020415789.1"
                     /locus_tag="HUW46_RS43020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08523"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_215544387.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-07, bitscore: 30.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-12, bitscore:
                     45.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAALFDSYGPPDVLYEGKVPVPTPKQDEVLVKVHAVSINGGEIS
                     ARAGRVRLLTGRKFPQRVGLDFAGEITEVGPAVKGPAKGDRVWGTLPRGRFGSAAEYVT
                     VRPAQISLAPQGISLVDAVSLPVGTTAITALRTQARLQPGERLLVRGGSGGVGSVAVQL
                     GKAVGAHVTALASPRNLDFVRELGADEALSYTTASPSTLGTFDVILDTAGTEHAAYRRL
                     LAPGGRMVAIAFDTKNPLPSIAYILASTVHGPRRVRFFSGNPKHDLFAELTRYVDSGAI
                     RPVVDTVHPLSDIAEAHRAMEAGGVRGKHIVQIYG"
     aSDomain        15965..16840
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS43020_PKS_ER.1"
                     /evalue="1.40E-40"
                     /label="HUW46_RS43020_PKS_ER.1"
                     /locus_tag="HUW46_RS43020"
                     /protein_end="312"
                     /protein_start="20"
                     /score="131.3"
                     /tool="antismash"
                     /translation="PVPTPKQDEVLVKVHAVSINGGEISARAGRVRLLTGRKFPQRVGL
                     DFAGEITEVGPAVKGPAKGDRVWGTLPRGRFGSAAEYVTVRPAQISLAPQGISLVDAVS
                     LPVGTTAITALRTQARLQPGERLLVRGGSGGVGSVAVQLGKAVGAHVTALASPRNLDFV
                     RELGADEALSYTTASPSTLGTFDVILDTAGTEHAAYRRLLAPGGRMVAIAFDTKNPLPS
                     IAYILASTVHGPRRVRFFSGNPKHDLFAELTRYVDSGAIRPVVDTVHPLSDIAEAHRAM
                     EAGGVRGKHIV"
     CDS_motif       16262..16300
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS43020_0001"
                     /evalue="3.60E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="HUW46_RS43020"
                     /protein_end="132"
                     /protein_start="119"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="VDAVSLPVGTTAI"
     CDS_motif       16334..16393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS43020_0002"
                     /evalue="9.70E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="HUW46_RS43020"
                     /protein_end="163"
                     /protein_start="143"
                     /score="15.0"
                     /tool="antismash"
                     /translation="GERLLVRGGSGGVGSVAVQL"
     gene            complement(16846..17541)
                     /locus_tag="HUW46_RS43025"
                     /old_locus_tag="HUW46_08524"
     CDS             complement(16846..17541)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680358.1"
                     /locus_tag="HUW46_RS43025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08524"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_215550454.1"
                     /transl_table=11
                     /translation="MRPIDLAREHGLSAQAIRNYDDAGVFPPTERSETGYRRYTPLHAQ
                     ALRAFLALRGGHGHQQAVEIMRSVNRGDTESAYRLIDAAHVALLAERDTSAEVAAALGA
                     LSTTTPSQATGRPLTVGELARRIGVHPATLRTWEAEGILRPERGRATGYREYGPDCVRD
                     AEIARQLRRGGYLLRQVAQFLRSLREAGGADALGVFLDSWRDRLAARGRALLAGAAQLH
                     AYLTVLDQP"
     misc_feature    complement(17620..17634)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            17657..18865
                     /locus_tag="HUW46_RS43030"
                     /old_locus_tag="HUW46_08525"
     CDS             17657..18865
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010316483.1"
                     /locus_tag="HUW46_RS43030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08525"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_215544388.1"
                     /transl_table=11
                     /translation="MSTATALRGIGHQLDDQPSLGRAIDELLAARTAPTLLALGEPTHG
                     IKAFPLLRNELLAHLAERGYRSIALETDIFAASVVDDYVAGGAAELDDVLKTGFSHGFG
                     SIPGNRELVEWLRAHNAERPPHDRVRFRGFDAPLETTSAPSPRHALLAVTDHLPESLRP
                     ASAHDLDALLGDDEDWTNEAATFDPALSIGDSDRARALRIVADDLVSALRRAAPGLHSA
                     DPAGYANAVAHARTAQGLLRYHAAMASTGPDRVAIMLSVRTEMMADNLHAIVAAEQGRG
                     PTLVFAHNVHLQRAQPGTAIGDVSWCSAGALVELTMGERYAFVATDANPASDPGTLQGA
                     LAGATTRRALFPAADLRAALAPSIGKGQPIVPGHLPLDPAELAGADAVIFIADTDGKRH
                     QYW"
     gene            complement(18895..19446)
                     /locus_tag="HUW46_RS43035"
                     /old_locus_tag="HUW46_08526"
     CDS             complement(18895..19446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643298.1"
                     /locus_tag="HUW46_RS43035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08526"
                     /product="DinB family protein"
                     /protein_id="WP_215550455.1"
                     /transl_table=11
                     /translation="MDVDWVAELGDQLDWHWRERLRPRLAGLSDEEYFWEPVPGCWTLR
                     PRREESEIGGGRLTVDYAFPTPEPAPVTTIAWRMAHLTVHVLGKRAETQFGGPPVQYDT
                     FPFAATAATALNQLDAAYDAWSSGLRALSPVDLARVGGAAEGPFADRPLPALVLHIHRE
                     VIHHGAEIALLRDLYLRRRP"
     gene            complement(19475..20545)
                     /locus_tag="HUW46_RS43040"
                     /old_locus_tag="HUW46_08527"
     CDS             complement(19475..20545)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020494626.1"
                     /locus_tag="HUW46_RS43040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08527"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_215544389.1"
                     /transl_table=11
                     /translation="MTTGSTAWTALRLRESLLPNRVWLSPMCQYSADGSGAPTDWHLAH
                     YGARAAGGVGMVMVECTGVSPDMRTTKRDLGLWSEHQVRGHRRLAAAIRAIGSVPAVQL
                     GAAGRKSSHGVPWDNAGTRRPIGPEDGGWRPLAPSPIPFAGLGVPAEMTTKDGTRVLED
                     IERAARNAHRAGYEVVELHGANGYLLHEFLSPLANHRVDEWGGDLERRMRFPLEMVRAI
                     RAGWPADKPVIVRLPAADLHEGGLTADEAASVASRMARAGVDMIDISSGALTPGALRIE
                     KPLHNAEYGPRFRAAGVLTAASGLVSEARHLDEAIPDLVDAVLVGRAMLRDPYWALRAL
                     DAEPHRSWPRQYHRAF"
     misc_feature    20622..20635
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.39"
                     /tool="antismash"
     gene            20645..20959
                     /locus_tag="HUW46_RS43045"
                     /old_locus_tag="HUW46_08528"
     CDS             20645..20959
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020494762.1"
                     /locus_tag="HUW46_RS43045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08528"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_215544390.1"
                     /transl_table=11
                     /translation="MPRQPEHPDLEDVQLARVFSALGDPARLRIMTVLADRTEHQREEF
                     TVDVGPSTLSHHMKILREAGLTHHRFEGTRCFVSLRADTFDRFATVLDSTLQLLATDQG
                     "
     gene            complement(21127..21426)
                     /locus_tag="HUW46_RS43050"
                     /old_locus_tag="HUW46_08529"
     CDS             complement(21127..21426)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS43050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_08529"
                     /product="hypothetical protein"
                     /protein_id="WP_215544391.1"
                     /transl_table=11
                     /translation="MSGMRKMASAALAAAGAAGLMVAGATGTASAAPVAPQGGTCQYAY
                     CLIERGNPPWDEQTCVGTASYRYVDLFQVHPGYNCYWESNNTWAIYAENGAPMP"
     misc_feature    21497..21512
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.16"
                     /tool="antismash"
     misc_feature    21576..21596
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.31"
                     /tool="antismash"
     misc_feature    21581..21596
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            complement(21621..22001)
                     /locus_tag="HUW46_RS43055"
                     /old_locus_tag="HUW46_08530"
     CDS             complement(21621..22001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034383.1"
                     /locus_tag="HUW46_RS43055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08530"
                     /product="hypothetical protein"
                     /protein_id="WP_215544392.1"
                     /transl_table=11
                     /translation="MRGLAERADSSLDETGHNRKRSGRHCGWCGLHLPEGANIGRRRRY
                     CGQSCRQRAYERRAAVQRTGLPEDAVVLSATEIAELQDRLFQLRCAAEDVVTAADDGAE
                     PGELRRMAAELAEAAKDLEQLR"
     gene            22068..22853
                     /locus_tag="HUW46_RS43060"
                     /old_locus_tag="HUW46_08531"
     CDS             22068..22853
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154488.1"
                     /locus_tag="HUW46_RS43060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08531"
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="WP_215544393.1"
                     /transl_table=11
                     /translation="MTQPHPYLADPHPRAFVHRGWHLDELAGLENSLPAFRRAVDEGFR
                     YLETDVHASSDGVVVVHHDATLDRTTDGKGTIASQSWPALSKVKIGGKAPLSRLEDLLE
                     ELPNACFNVDVKTDAAVEPFLRTLAKTNSYDRVAAAAFSDGRLAKLRKLAGPRLLTSMG
                     PRSAAALWARGLAPLLPLGFLTAGAMAQVPIRQGWLTIVDKAFLRAAGRAGIEVHTWTI
                     DDAPVMRRLLDLGVHGIVTDRPDVLRDVLTERGAWHPAG"
     gene            complement(22860..23558)
                     /locus_tag="HUW46_RS43065"
                     /old_locus_tag="HUW46_08532"
     CDS             complement(22860..23558)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226559.1"
                     /locus_tag="HUW46_RS43065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_08532"
                     /product="transglycosylase family protein"
                     /protein_id="WP_215544394.1"
                     /transl_table=11
                     /translation="MTKLRRGGVTRGVARLLLLAVGVLGFQIAVSTPASADPSAGLWAK
                     LRMCESSGRYDINTGNGYYGAYQFNLATWQSVGGSGRPDQASPAEQDFRALYLYRMRGW
                     QPWECAGMLGFSNDRDARTKRTPSYHESAYIGGRPLPPVPPAPKPPAPPGGPKPAWPGV
                     VYAYGDCAPALKAFQLRMNAFGYGFSGTGCYYEKTKTAVLDLQRVNAINDSGRLGPKTW
                     KAAWEGKPPR"
     misc_feature    complement(23898..23913)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.37"
                     /tool="antismash"
ORIGIN
        1 agacgacgtc gtgctcgcga cgaaggtgca cttcccggtc ggcggcgaag ggccgaaccg
       61 cggcggcaat tcgcgccgct ggatcgtgcg cgccgtcgag gaaagcctgc ggcgcctcag
      121 gacggactgg atcgacctgt accaggtcca ccggccggac cacacgaccg atgtcgagga
      181 aaccctgtcc gtgctcggcg atctcgtgcg gcagggcaag atcagggcgt tcggctgctc
      241 gtcgttcccc gtcgaggaca tcctggaagc gcactacgtg gccgaacgcc gtggcctgcc
      301 gaggttccgc accgagcagc cgccgtattc gttgctcggg cggggcgtcg aacgatccgt
      361 cctgccgacg tgccagcggc tcggcatggg cgtgctgacg tggagcccgc tcgcgtggag
      421 cccgctcgcg tggggcgtgc tctccgggcg gtaccgcgcg ggcgagccgg tcgacctgac
      481 cagcgggcgc ccggcgctca acccgggccg gttcgatcca gcgctcccgg agaacgcggc
      541 caagctggcc gccacggaga agctcgccca gctcgcggac gagctcgggt gctcgctgcc
      601 ggatctcgcc atcgccttcg tcgtggcgca tcccgccgtc acgtcggtga tcctcgggcc
      661 gcgcacgatg gcccagctcg aatcctccct gaaaggcgcg tcactggtgc tggacgacga
      721 gacgatggac cggatcgacg agatcgtgcc gccgggcaag gaccagtacc acgtcgacgc
      781 cgcgtggagc ccggcgtcgc tgaccgacgt cgccaggagg cgccgcccgt tggccgagcg
      841 cgccgcggcg tagttgcctt ccgagcggtt gtacctacta gtatgtacgg cagacaaccg
      901 ctcggaagga gcaccacccc catgccattc gttcggatcg acgcactgcg agcagacccc
      961 gaccgcctcg acgccttggg ccgcgccgtg cacgacgcgc tggtcgaggc gatcggcatc
     1021 ccggccgacg accggttcca ggtcctgacc gggcacgacg gcgcgcggag caccctgcgc
     1081 tacgacgacg gctaccttgg cgtgcaccgc gacgacgacc tcgtgttcgt cgcgatcacg
     1141 atgcgatccg ggcggacgcc cgcgctgaag caggcgctgt accggcggat cgcggaactg
     1201 gcgcacgagt acgcgggcac cgaaccgcgg aacgtgttcg tcaccgtcac cgaaaacgag
     1261 ccgatcgact ggtccttcgg cgacggaatc gcgcagtacg ccgaaaaagc acctctccac
     1321 tagccgaccc gctggtgtag tactggcagg gccagctaag ccgttggtga tcgactgggc
     1381 gcgatgcaga ctcagggcat gcgcaacaac gacttgggcg agttcctgcg ggcgcgccgc
     1441 gccggactca agccggacga gatcggcctg ccggtcgagt tcggcggcgg gcgccgggta
     1501 tccggtctgc ggcgcggcga ggtcgcgcag ctggcgggag tgagtgccga gtactacacc
     1561 cggctggaac agggccgcgc caggcagccg tccgaacagg tgctgcacgc cctcggcgac
     1621 gcgttgcggt tcgacgacat cgagcggcgg catctgttcg ccctcgcggg caccacggcc
     1681 gggcgccagg accgggccga gcactcgtca cggctacggc ccgcactgcg gcaggtgctg
     1741 gagtcgatgg agctggcttc tgctttcgtc agcgaccaga acctcaccgt cgtcggcggg
     1801 aacgcgttgt gggcgttgct gttccccgat gtggccgagc tgccgcgccg ggaacgcagc
     1861 atggcgcgct ggacgctgct ggatccgcgc gctcggttgg tgtggtgcga ctgggaacgc
     1921 gtcgcccgcg actacgtgca cgggttgcgg ctggccgccg ccgcgcagcc gcggaaccag
     1981 cacatcgcca acctgatcgg tgagctgatg atgcgctcac ccgagttccc ggcgtggtgg
     2041 tcggaacacc gcgtccagga acgcagcacc ggcctcaaac gcctccacca cccggtcgtc
     2101 ggcgacctgg aactgcagta cgagatcttc acctcggtcg ccgacgccgg ccaatcgctc
     2161 gtcgtctaca ccgcgccgtc cggctcgccg tcacaggagc gcctgcgact gctggccagc
     2221 tggagcagcg aacccgcggc cgccaaggac accgccgagt cctgaccgct gcccgaaccg
     2281 ggccatcccg ccacgacccc gccctgcccg cgaggtcgat gtcgtcgtgc ccggccgatc
     2341 ccatccacga gaggaaatcc gtagtgagca agacattcct gatcaccggc gtcagcaccg
     2401 ggctcggact ggccatcgcc cgacgggcac tggcggccgg gcaccgggtc gccggtaccg
     2461 tgcgcaccga gcagcacgcc gccgccttcc gggcactgga ccccgaccgc gtccgcgcct
     2521 tcatcctcga cctttccgac gcggaccgga tcgaccccac cgtgcgggcc gccgaagcgg
     2581 aactgggccc gatcgacgtg ctcgtggcca acgcgggcta cgggctggaa ggcaccttcg
     2641 aagaatcgtc gatggccgag ctgcgccgcc agttcgaggt caacgtgttc ggcacggtgg
     2701 cgaccgtgaa agcggtcctg cccggcatgc gggaacggcg cggcggccac atcttcgtga
     2761 tcacctcgat gggcgggcac accaccttcc ccgggctggc gttctacgaa ggcagcaagc
     2821 acgccatgga aggcatcacc gacaccctcg cccaagaggt cgcccagttc ggcgtgcggg
     2881 tcaccgccgt ggcccccggc gcgttcaaaa ccgactgggc tggccggtcg ctggtccgcg
     2941 cgccacgcgg catcgccgac tacgacgcgc tgttcgaccc gatccggagc cgccgccagg
     3001 ccctcgcggg tcagggcatt ggcgaccccg atcgcgcggg cgacgccatc ctcgccctcc
     3061 tggacgtgga gaagcctccc gtgcaccttc tgctcgggtc ggacgcgctg cgcctggtcg
     3121 ccgccgggcg ccgacgcgtc caggacgaca tcgacgcctg ggaggaactc agccgctcca
     3181 ccgactccac cgaaggcgga gtgacggtcg cctgacaccg gctaccccag ctggtcgcgg
     3241 cggcgggtca ggtaggcggt ctcggcggtg ttgcccgcca gctcgatggc cttgtcgtag
     3301 gcggcacggg actccttgcc gcggcccagc ctgcgcagca gatccgcgcg ggtgacgtgg
     3361 taggggtggt agccggccaa tctgtgctca agacggtcga cggccgccag cgccacttcc
     3421 gggccgtcga gttcggcgac ggcgatggcc cggttgaggg cgatgaccgg cgaggcgtcg
     3481 aggcggacga gctggtcgta gagggcgagg acctgtgacc agtcggtgtc gcggacgtcg
     3541 cgggcggagg tgtgcacggc gttgatcgcg gcgaggatct ggtagcggcc cggcgccact
     3601 ccggcggcga gacgctcgcg caccagctgg tggccctcgg cgatcatgcc cgtgtcccag
     3661 gccccgcggt cctgctcgtc gagagcgacc agctcaccac tggccgacac cctggctgga
     3721 cggcgggcct cggtgagcag catcagcgcc agcagcccgg ccacttcacc atcgtccggc
     3781 aagagtgcgc ggatcaggcg agtgaggcgg atcgcttcgg cggtcagctc gtggcgcatg
     3841 ggatcggtgt cgggaccggt cgccaggtag ccctcgttga acacgaggaa gaggacggtg
     3901 agcacgccgg tgagacgggc agggaggtcc tcggccgacg gcacgcggta cgggatgcgg
     3961 gccgccttga tcttggcttt cgcgcgggtg atccgttgcc ccagcgcgct ttcggccacc
     4021 aggaaggcgc gggcgatctc gggcacggtc aggccaccga ccatccgcag cgtcaatgcc
     4081 aggcgcgctt cggtcgccag cgccggatgg cagcaggtga agatcagccg gagccggtcg
     4141 tcgtcgatgg caccgagcgg ctccggcggg tcgtcgtcgt acaccagctg agcctccttg
     4201 tgcttgtcgt cgcgcttggt ctcgcgccgg atccggtcga tggcccggcg ggtggcggtg
     4261 gtggtcagcc acgcgccggg gttgggcggc acgccgtcgg caggccactt ctcgacggcg
     4321 gcagtgaacg cctcggccgc ggcctcttcg gcgatgtcga ggtcaccgaa gcgcctggtc
     4381 agtgcggcga ccacccgggc ccactcctcg tggtgggcgc gggtgatcga ctcttcgacg
     4441 tcgttcactg gaacggccgc acctcgatct tccgatcgca ggccttcgac gcctcggtcg
     4501 cgagcttgag cgccacgtcc agatcgggga cctcccacac ccagacgccg gcgaggtact
     4561 ccttggactc cacgaacggc ccgtcggtga ccaccgcctg ctcgccccgg ttgtcgatca
     4621 ccgtggccgt ggcggtgtcc gcgagtccac ccgcgaaaac ccagtagccg tcggcgatca
     4681 accgttcgtt gaacgcgctg atggcgggct gcctgtcggt gctgccgggg ttttccttgt
     4741 catcgatcac ggaaaccagg tactgcatct gaagatcctc tcctgtggtg tcgggacggt
     4801 gtggtctacc gggccggcgc gtaccgcggg cgtccggcag gccggaagac ctgcgtcgtc
     4861 acgcctttcg agtcgacccg tgagtcgatc aggtcgagcg cgaggtccgg gccggtctcc
     4921 gggaacaagc gcgtgccctg gccgaggatc accgggacca cgagcagggt catctcgtcg
     4981 accaggccgt tctccagcag ccaccggatc aaggtgccgc tgccgtggac gtgcagctct
     5041 ccgccgggct tggctttcag ctcggcgatg gcggccgcga gatcgtcgga caggaccgtg
     5101 gtgcccgccc acgccggatc ggtcagcgtg gtcgacgcga cgtacttggg ccgggtgttc
     5161 aacgcccgcc ggacgggctc ccagtcaggc acgtggtgtt ccgtccagga tccccacgag
     5221 gcggcgaaca gctcgtaggt acgcctgccg agcaggaacg cgtcggcgcg ctggaaggtc
     5281 tgcttgatca acgaatgcgt gtcggcgtcg ccgcgcccga gggcccatcc gccgcgttcg
     5341 aatccgttcc tgcggtcctc ttccgtcgct ccgccgtctc cctgcaccac gccgtcgatg
     5401 gtgaccttgg ccatggtggt cagcttcatg atcgcggttc ctccgccctt ggcgccgccc
     5461 ctgtcgggcc gcttcacccc tgctacgaac gccaccgcgc cgatccgaca acgccgcccg
     5521 gaatttcttc gaagaacttt ccgggcggcg gtcgccttcc tcagggctag gccgcgggag
     5581 tccggctgaa gatcgtgagc acggagccgt cagggtcccg catccaggcg acccggatgc
     5641 cggaggtgtc cgccgaaacg ccgtcctcgt cgagcgcgaa gggcagatcg tccttgccga
     5701 ggaagggaac cccgcgggag cgcagggttc gcaccgtctc gttggcgtcg tcgacgcgga
     5761 tgctggccac cggccagctc ggcgatcccg catcggatac gctcgcgagc aggtagatca
     5821 ccgtgccttc gctgccgcgg agcagccagc cacctggtgc ctcctctccg gccagcccca
     5881 gtttctcctc gtagaactcg cgtgcccggt cgagatcggt cacggcgatg acgggtccga
     5941 tgtgcatcag tgcttccctc cagtgcgaga cgcgtccgac ggtatcggct cttccgtccc
     6001 gtgccaggtg tcggcgacca gatccacggc gctgcgggcc ggatcgcggg ccgcgtggtc
     6061 gtaggtctgc tgggtggtgt cgatgctgct gtggccgacg tccgcttgga cgtgcgtcag
     6121 ctgggcaccg gcctcgacgg cggtggtgac gtagaagtgg cggagggcgt ggggatgcag
     6181 ggcgcccgcg atcgcggtca gttcttcgcc accggcggcc gcgacgcggc gcagcagctg
     6241 ccagatcgcc tgccgctgga agcggcgccc ggtcctggtc aacaggagcg gggtggtgtc
     6301 ggcgcgggtt ccccgttgcc gcctggtcac cgcggcgccg gtggccttcc cggtgtcgtc
     6361 gcgcagcacg aggtaacggg tgagcgccgt gtcggcgggg ccgctgaggt agacgatccg
     6421 gtccttgccg cccttgccgt gcactcgcag tgcgcgcctt cccctggtga cgtgcaggtc
     6481 ggcgcggtcg aggccgcaca gttcgctgac gcgcagcccg agggtgaaca gcgcgatcac
     6541 cgcgaccgcc cggtgcgtgt cgagcgcgct cgcacccggg cgccgttgcg ccgcggtggc
     6601 gtagagcgcg cggacctgcg cgctggtgag cgtgacggtg cgcgacgtcc cggccgccgc
     6661 ggcggtgagg ccgagtcgtc gccggttcag cgcggcgggg ttcgcggtga cgacgccgat
     6721 ttcggccagg taggcgtaga gcgccttgac ggtcgcgagc atgcggtcgc gggtcgccgg
     6781 tgccgcgtcg gcaccggcca gtgcgtcgag ccaggacttc acgtgccgcg aggtcgcggc
     6841 gcggggatcg acgccggtgg ccgcgcacca gcggaaccag tgccagcggc gcagccgtcc
     6901 cggcgcggcg ggtgggggac cgggccgctt cgcccggctc tccgtcgcgt cgatgcgcag
     6961 aacgtcctgg tagcgcgcga gcacgctcgt ccactcgccg ccgcggctcg gctgctccca
     7021 ggcgtcgatg tccgagggcc gcgtggggag tccgagccct tcggcgtagg tgcgtcgggt
     7081 ggcgtggttg ccgtagcccg ccagccagtc cgtgatgtgg ccgagcaggg ccgcgggatc
     7141 gtcgacaccg ggccacaggt ccacgtcggc ggcgagggcc cgcccagttt tcgccgggta
     7201 cccggcagct tcggtcgccc ccgaagtcgc acgctcagtc accagcaaaa tcactctctg
     7261 tcgccgaatc agtcttgatc aaggttagca acaaaagatc tgttctgtag ccaacttagc
     7321 ttatggtttt gaaaatctaa acccaggtat ctagttatgt aaccttcaag ctatgctttg
     7381 tggcatgctg gagacgacca ccacggagcc ctcggaacgg gcgctgtgcg cgttccgacg
     7441 ctgccgccag ccgttgccgc cgccgggccc caagggcgga cggccggtgg agttctgccc
     7501 ggaccggtcg tggcagggcg ggaagagctg caagcagctc gcggccgcgg accaggccct
     7561 gcgcgaggcg ttcggcgact cggcaccgca ggcggccctg caggacgcga ccgccgcctt
     7621 cgccgacctc gccgacggcc tggccgcacc actgagcgaa ctccaacgct cactggaaac
     7681 cgtgtcggcc tcggccaggg acgaggtagc cgcgtccctg acccgcgcca ccgccgccga
     7741 cgaacgcgcc gccgaagccg acggacaccg ccaggctgcc gaggaccggg cacgacaagc
     7801 cgaggacgac gcccgcgccg cacgggacga agcccaggaa caccagcgag cacgggagaa
     7861 cgccgaacga gccgagcagg cagccagagc cgacgcgaag aaggccgaac tgcaccaagc
     7921 ccgcgccgaa gcgtccgcgg ccgcgaccgc tgaacacgcg cgcgccgccg ccgaggaagc
     7981 tcgcaccgaa cgcgccaagg gggagaagct cgccgcccag ctcgccgagc gcaccgaaca
     8041 gctcggcgtg gcaacagccg aacgcgacgc cgtccaagac gcgctcgacc gcgaacgcac
     8101 acgggccgtc gatgcccagc agcagctcgt cgcccggctc gaccgcgccg ccgcggacct
     8161 cgacgccgaa cgcgaccacg cccgagagct cgaacagcag ctgcgcgacg cggttcacca
     8221 gagcagaacg gacgccgcca cggcctcggc ggcgctgacc agcgcccagg aacagacgcg
     8281 ggaactggcc gccgaactca ccgaacaccg gcgacaagcc gcgaccgtgc tggccgaccg
     8341 cgacgacgcc ctcgcccggc tcgcccgcgt gcaccggatc gccctcgaca ccaccgcgga
     8401 agacctgcgg accgatctcc tcgccgaact gctcgcgctc cccgccacgc cacccgagta
     8461 acgcccgata attgtccatt gtggacttca gttcttcggg aacggcgtcc cgtcgccggt
     8521 cggtatggca tcctgatcgc cgatgacgat acgttctggg gagatcgctc gaagccgtgc
     8581 ggcgttgatg gtcgcgctga gcgtcgacaa cttcgggtcg ggattgtttc tgccgctgtc
     8641 gttggtgtac gccacgcagg tcgtggggtt gccggtggcg caagcgggtg tggcgatgac
     8701 ggtggggacc atggccggtc tcgtggtgcc ggccgtgtcg gcggcgatcg tggaccgggt
     8761 gggcgcccgt gcggtggtcg tcgcggggca gctcgtgcag ttggccggat ccgtgacata
     8821 cctgctggcg cacggggtgg tgctggtcgc ggtgggtgcg gcgatgcggt cggcggggtt
     8881 gcagttgttc tacagctcca tgttcaccct gatcaccgag gtggcaggcg acagatcgac
     8941 cgatcggacc tttaccgtgg tgggcgccgt ccggggcgcg gcgttcggga tcggcgcgct
     9001 ggccgtgggc gcgctgctga ccgggctggg ccccaccgcg tacacgctcg cgatcggtat
     9061 cgatgcgacg acctacgtcg tcgcggcagt gctgctgctg tgctggctcc ccacgccggc
     9121 acctcgtcgg gccgcgatgg acgccgcgac gcgagaagtc cgtccgaggg cgagcagagt
     9181 gctgcgtgat ccgccgtatc tcggcctgat cgtcgtgacc acgctgttcg ccctggacac
     9241 cgacttcttc ctggtcggct tcccggtcta cgccttcgac atcctccaca cgccggcgtg
     9301 ggtgcccggt gccgcgctcg cgctgctgac cgcgctcggc agcgctgccg ccacactggc
     9361 cctgcggatg acgcggcgcc tctcgcggac cacggccatg gtcttcgccg cggtgatcgt
     9421 cgtcggttgg tgcctcgccg gcgccgcggc tctggtgctt ccggccggtg tccggcccgc
     9481 gtatctgctc ggctgcacac ttctgctggt cgcggccaat ttggtccgcg cgggacgggt
     9541 caacgcactg gccgaaagcg cggccccacc agaggcgaag gggcgttatc tcgcggcttt
     9601 ccaatacgcc ttcaccatcg ccggagtact ggcgccggcg gtggtggcgc tgttcgctgt
     9661 cgccgcgtgg ctgccctgga tggtgatcgc cgccggcgcc gtcttgggaa tcccgctcct
     9721 gcactggata acgcggcacc tgcacaccgg ctgcgcggaa ccacgtccgg cgtgagttcc
     9781 gggaccggtc ccccacgagt cgtgattcgt tgtcacggga acgaaccaca actcgtcgac
     9841 cgtgacacgg gggtatgccg tggggaaccg atccgtccca cgcccgtcgt tcttcctggt
     9901 cctgccggac cgcgcccttc ctgaggagtt gggggttcgg accggcggaa tcccggtcct
     9961 ggccaggcac cactccggtc gcccctggtt actcggcacg atgccgcgga agcagctgac
    10021 aatccacgct gagggacagc gacgcctcgc gctgctggga accaccacgg cgacctgtca
    10081 cgatctcggt cgggtgtgcg accgttcgcg ggacatcgcc gatttggcgc gcgtgtcgaa
    10141 ccgtttcgcc ggggcgtacc acgtggtcgg ctcgttcgac ggtcgtgtct acgcgcaggg
    10201 ctcggccagc gggatgcatc gcgtgtacca cgtcgtcatg gacggtatcc gggtgatcgg
    10261 cgaccggatg gacgtgctcg ccgaactcgg gagccttccc gtggacgaca ccgcggtggc
    10321 gatgcggttg gtgcgcggtc ttccgcatcc gctgtcggac gttccgttgt ggtccggcgt
    10381 atccgccgtc gccgcacatg actgtctcat ggtggagacc gacggccgcg gctgggcgac
    10441 caggacctgg tggcggcgtc cgccaccgga gctgtcccga gcggaggggg cggcggagtt
    10501 gcggtccgcg ctcgccgagg ccgtgcgcgc caggaccgcg gacggcctcg tcacgtgcga
    10561 tctctccggc gggctggact ccaccccggt gtgctacttc gccgcgcgga gtccgtccgg
    10621 tgtcatcgtc aagaccagtt acaacaacga ccccggggga cgtcaagacc tcctgtgggc
    10681 gcgccgggcg ctgccggtca tgccgggggt ccgcgaccac gtcgtcgagt cgacggacac
    10741 catgcccgac ttttacggcg ggttgctcga ggtcatcgat cgcgtggacg agccgacgca
    10801 gagtttgttc tgcgcaccgc gtatcggcca ccagctccga tacgacgcgt cgcacggtgt
    10861 gcggacccac ctcaacggac tcggcggtga tcaggttctg tgcggctcgg cgagctggga
    10921 ccacgccctc ttcgcccgca agcccctgcc ggcctggcgc cgcgcgcgtg ccctgcacgt
    10981 caccgacggg cactcgccat gggccaccct gcgagcgctg tgcgatcgaa gcgattaccg
    11041 ggcatggtcg gccaggatca tcaggaacgc tgccgccgca gcacccggcg gaacgcgggc
    11101 aatgctctgc ggctgggcac tggccccccg gttcccgtcc tggttgtcgg ctgccgccaa
    11161 ggacatgctg agcgaagcga tgctgcgcac catgcgagac gccgacccca tcggggcgga
    11221 tcgggccgag caccacgagc tgtcggagat acgcgacgcc gcacgaatgg tccgggggag
    11281 tgcccagctg ggcgcgcggt tcggcgtgag ccacgaggca ccgctgctgg acgaccgtgt
    11341 ggtggaagcc tgtctcgcgg tgcggcgcga agagcgggtc acgccggtcg aatggaaacc
    11401 gctcatgaag gcggctatgc gtggcttgct gcccgacgcg ttcctccgga gggtgaccaa
    11461 aacgggtggg ggcgagcagt tgatgcgggg attccgggcc caccggcggg acgtgttgac
    11521 gctgtgcgaa agctccggcc tcgatgagtc gggctggatc gacatggccg agttcaccgc
    11581 agcggcgacc ccgaccgagc tggaactgcc ggacacgtcg ttgaacgagg cggtcaacct
    11641 cgcgctgttc atcagagggt cgctggacgt ctcgcggaac atccaatgga atagccgttg
    11701 acctggaccg atggtcagcc gagtcggcgg gggctggatg gcgtctcgga gagatcgaag
    11761 gggacagggg agtggccttc ccagatctgg cgggatgcct gttcggggta gggcagagtc
    11821 ttcgactcgg tgtccaggac gcgggtgagg tacccgccgg gccggtgggc ggaccagccc
    11881 gcgtcgccgg tggtgacgaa gcggacccat gcttcctgga gttcgcggga gagcgcgacg
    11941 gcctcgggag tggggtcctc gccgatgagc tgggtgccga cggggctgtt cagcgtgccg
    12001 aacgccaggg gcacgtcgag gctgtggcag gcgcccagga tgccgccgag ggccggggcg
    12061 acccagcaca gttcgaacag gtacgaggtg ccgccggctg cggcgttcgc ctcggccagc
    12121 ttctgtgacg gcatgcggaa gagggcgtcg gagtacaccg tctccaccag ttcctccggg
    12181 cccgcctggc cgaacgcggc acggtaggcc cgcgcgccgc ccggccgcgg ggcgagcagt
    12241 tccaggaccg cgtgggcgtc ctcctcggtg aaggtgccgt gccgtccgct catgacgctg
    12301 aagtaccgga attcgtcgcg ggtgtggccg acgagcagtt cggtcccgct cgcgcgtgcg
    12361 ccggtcagcg cgggccaggg cgtttccggg aggacctcgc cgtcgacgac ggggcacagc
    12421 gcggtgccgg tctccgtgag gcgtccccag ctctcccggt gcgcgtggag gccggcgttg
    12481 aaggaggtga gctcggcggc caggtgccat gggtcgatgt cgcgcagggc ctcggcggtg
    12541 ggggccgccg cgccgagccg gtccgcgaac gcggtgctga cctgccgtgc cagcgcgggg
    12601 gtgctgtgca gccccggcac cgaatgggcg atggcccgcc ggaacaggcc gcgcgcggac
    12661 ttcatcgtca gcagggcggc gaccgagcca gccccggcgg acaccccgcc cacggtgacc
    12721 ctgccggggt cgcctccgaa ggcggcgatg ttgcgctgca cccactccag cgccgcgatc
    12781 tggtcgagga atccgcggtt gggcggcacg tcgtcgagga acgcgaatcc ctccgcgccc
    12841 acgcggcagt tgatggtcac cacgacgact cccgcctcgg ccagcgccgc cgggtcgtac
    12901 atcggatcgc tcgacgccgc cgagaggtaa ccgcccacgg ggatccacac cagcaccggc
    12961 agtcccgccg cgccggggtc cggagtgccg acgttgagcg tcagccagtc gtcgccctgc
    13021 gggggcacgt cgatcggcag ggacagcggc accacggggc cgaactcgac ggcttgcctc
    13081 gtgccctccc agcggtgcgg cggcgcgggc gcggcgaagc ggagcgctcc gaccgggggc
    13141 tgggcgtaag ggataccgcg gaacaccgcg tgcctgtgcc gccagagccc ctgcaccacg
    13201 ccttccgtgg tccgtacctt cggctgttcg gacaggacga ctccctccct cgactggcct
    13261 ccagagttat gggtcaggtg tattatgtca actgtattgg aacagtcccg gggtacgagg
    13321 gaggggcctg cgatgccgaa acaggtggac caccgcggac gccgcgaagc gatcgcccgc
    13381 gcactgtggc gggtggtgga gcagcgcggc gtcgcacagc tgacgatgcg cgtggtggcg
    13441 caggaggcgg gcatgtcact cgggcagctg cagcactact tcgcctcccg gaccgccatg
    13501 ctctccttcg ccatggattt cgcgtccgag cagacctcgg cgcgcgtacg ccaggggctc
    13561 gaaaagctcg gcgaccgtcc gcacccccgt gacgtgctgc gactggcgct cgcggaaatg
    13621 ctccccctgc atgccgaggc ccgcgcgacc agccggatga gcgccgccta cgtcctggag
    13681 gcactgcacg acgaggtcgt gcacgagcag gcccgccgcg gcttcgtcca agggcgggcc
    13741 ctcgtcgagc agttggtccg ccaggcgatc gccgacgggc acatcgactc cggccgcgac
    13801 ccggcgaccg agaccaacct gctcctcgcc ctcaccggct tcacgcccct gatcgaactc
    13861 gacgtgatcg agccccagga cgcgctcgcc gcgatcgacg tgcagctgga ccggctgttc
    13921 agaagtacct gacctgcccg tcagatcctc cgcacgggac gctgaagaac ttccggtaga
    13981 acgcgctgtc caccggctcc ccgacgacct gctcgtcgac ctcgatccag gcatgtgccc
    14041 ggaacggcgg ggtggcgatg acgccgacgc acaacgtcgg ccagataccg cgggcacggc
    14101 ataccagcag caccgcgatc gacctcggca ggcaggtgtt cccggcacgg caccgtggac
    14161 tgaacgtcag gatctggtcc cgcgcgagtg cggcctgcgc ataactcgcc ggccgcgtcc
    14221 cggcggcgac cctgccgagc acgcggcgaa ggcggcgcgg cgactgcctg ctgaggattc
    14281 tcgccgacac cagcgcgagc gccatgacga tctcgccacc caatccagtg cgggtgggga
    14341 tttcgggcag gacctggctc acgccagcag cccccgctcg cgcaatgtgt cgatcgtgtc
    14401 gcgaacatcg gccagcgcgg tcttctcatc gatttcgaac cggtgcacga tccggcgcgc
    14461 cgcctcctcc gccgtgccgc ccgcaccgag cacgtcgagc accagcgccg ccgtcggatt
    14521 gacgtgccag taacgacttt tcacttcatc cagcagtact cgcccgtact cggtgtccgc
    14581 ttgggagacg ttccccttca gtgctctgtt cttcacgact cctcccaaag tgttgccacg
    14641 aaccgcattc cgggttcccc gagccgaaac ccggggaacc cggaatgctt gacaagaccc
    14701 actacgagga atgatcaagg caacgagaac acataggggt attgaacctc ggaaatgttg
    14761 ccccaggtgt tcagcgccgt ttcggtagcg aagcttccga gttcgacgac ggcaggagcc
    14821 tcgtagggtt gcttgacccg cactacttcg acatccatct tgacctcccg atcgacgtag
    14881 ggacgcacct gccatcgttc cgcgccgtcc ggggagggct cccggcgtag gctgctaccg
    14941 tcccgctccc gacatcgcgg cgggcgtggc aaggtagcgg catggatctg ctgccgcacc
    15001 tgcggcgtga ggtgcacgcg ttcgaatcgg tggcccgtgc cgctgccgac ggtggtgacg
    15061 ccccggtcgt gccgtcctgt ccagagtgga cggtgtccga tctcgtcgcc catctcggct
    15121 gggtgcaccg gtacgtgacc cacctcgtcg cgaatcacct gctcgagcca cccgacgagg
    15181 ccgacccgtc gttcgtcggc ctgcccgacg atcgcaccgg ctggccatcc ctcgacggca
    15241 cgcccagcga aggtcccgtc ctgcccaccc tgctcgactg gttcaccgag ggaatcggcg
    15301 cgctcgaatc ggcgttccac ggcgccgccc acgacgaacg ggtctggtcc tgggcagagg
    15361 accagacggc cgggttctgg ctccggacgc aggccatcga agcggccgtc caccggtggg
    15421 acatcgaaaa cgccgtcacc gcggcccagc ccatcgacgc cgcgctcgcc gccgacgcga
    15481 tcaggcacaa cttcgaggtc atggtgccga aacggcgcca tgacgcgccg tcggaaccgg
    15541 gacggggtga gcggtaccgg ttccgcgcga ccgaccgcga ggaagcctgg accgtccgct
    15601 tcgaccccgg cggtgtcgcg ttcaccgatg gccacgccga cgtcgaactc gccgcgacca
    15661 cctccgacct gatgctcttc ctctggcacc ggatccccgc cgaccggctc accgccaccg
    15721 gcgaccaggc ggtgctcgac cgctacttcg cgctcgtgcc cccggcctga aagtgttctc
    15781 cgccttctga gacgactgcg cggacatgtt tctcacttca gccagaacgg aaacgcgtcc
    15841 tccggatctc gcgttgacgc cactgaacgg aaacacgcac gagacaggac gccagatgaa
    15901 cgacatgcgc gcagcactct tcgacagcta cggcccgccc gatgtcctct acgagggcaa
    15961 ggtgcccgtt ccgaccccga aacaggacga ggtgctcgtc aaggtccacg ccgtcagcat
    16021 caacgggggc gaaatctccg ccagggcggg gcgggtacgg ctgctcaccg gccgcaagtt
    16081 cccgcagcgc gtcggcttgg acttcgcggg cgaaatcacc gaggtcggcc ccgcggtgaa
    16141 gggcccggcg aagggcgacc gggtctgggg caccctgccc cgtggccggt tcggcagcgc
    16201 cgccgaatac gtcacggtcc ggccagcaca gatttccctc gcaccccaag gaatatccct
    16261 ggtcgacgcg gtgtccctcc ccgtcggcac gaccgcgatc accgcactgc gcacccaagc
    16321 ccggctccag ccgggggagc ggctcctcgt ccgaggcggc agcggcggcg tcggcagcgt
    16381 ggccgtccag ctcggcaaag cggtcggcgc ccacgtgacc gcgctcgcca gcccccgcaa
    16441 cctggacttc gtacgcgaac tcggcgcgga cgaagcgctc agctacacca ccgcgagccc
    16501 gtccaccctc ggcaccttcg acgtcatcct ggacaccgcc ggcaccgagc acgccgccta
    16561 ccgcaggctc ctggctcccg gcggcaggat ggtcgccatc gccttcgaca ccaagaaccc
    16621 gctcccatcg atcgcctaca tcctcgcctc cactgtgcac ggtccacgcc gcgtccggtt
    16681 cttcagcggc aaccccaagc acgacctctt cgccgaactc acccggtacg tcgacagcgg
    16741 cgccatccgg cccgtcgtcg acaccgtcca ccccctgtcg gacatcgccg aagcgcaccg
    16801 cgcgatggag gcgggcgggg tgcgcggaaa gcacatcgtc cagatctacg gctgatccag
    16861 caccgtgagg taggcgtgca gctgcgccgc gcccgcgagg agggcgcggc cgcgcgcggc
    16921 cagccgatcc cgccaggagt cgaggaaaac gcccagcgca tccgccccgc ccgcctcgcg
    16981 caacgaccga aggaactggg cgacctggcg cagcaggtac ccaccgcgcc gcagctgccg
    17041 cgcgatctcg gcatcgcgca cgcagtccgg cccgtattcg cggtaaccgg tcgcccggcc
    17101 gcgctcgggc cgcagtatcc cctccgcctc ccaggtgcgc agcgtcgccg ggtgcacgcc
    17161 gatccggcgc gcgagctcgc ccacggtcag cggccgcccg gtggcctggc tcggcgtcgt
    17221 cgtggacagc gcgccgaggg ccgccgccac ctccgcactg gtgtcgcgtt ccgcgagcag
    17281 cgcgacgtgc gcggcatcga tgagccggta ggcggactcg gtgtcacccc ggttcaccga
    17341 acgcatgatc tccacggcct gctggtgccc gtggccccca cgcagcgcga ggaaggcgcg
    17401 caacgcctgc gcgtgcaagg gtgtgtaacg gcggtagccg gtctcgctgc gctcggtcgg
    17461 cgggaacacc cccgcgtcgt cgtagttgcg gatcgcctgc gcggacaacc cgtgctccct
    17521 ggcgaggtcg atgggacgca gcttgcacct ccgtttgagg cttccacacc cataaacgag
    17581 gtagaagttc gccgaagttc cactcgattc ttcaacgata tcgtcaaagg agattactca
    17641 aacggaaggg gtgcgcatgt ccaccgccac cgcactgcgc gggatcggcc accagctcga
    17701 cgaccagccg agccttggcc gtgcgatcga cgaactactc gcggcacgga ccgcgccgac
    17761 cctgctcgca ctgggcgagc cgacccacgg gatcaaggca tttcccttgc tgcgcaacga
    17821 actcctcgcc cacctcgcgg aaaggggata ccggtcgatc gcgctggaga ccgacatctt
    17881 cgccgcgtcc gtcgtcgacg actacgtggc cgggggagca gcggaactcg acgacgtgct
    17941 caagaccggg ttcagccacg ggttcggcag catccccggc aaccgcgaac tcgtcgaatg
    18001 gctccgcgcc cacaacgccg aacgcccgcc gcacgaccgc gtccgcttcc gcggcttcga
    18061 cgcgccgctg gagacgacca gcgcgccgag cccgcggcac gcactccttg ccgtcaccga
    18121 ccacctgccc gaatcgctgc gccccgcatc cgcccatgac ctagacgcgc tgctcggcga
    18181 cgatgaggac tggaccaacg aggcagccac gttcgacccc gcactgtcca ttggcgactc
    18241 cgaccgcgca cgcgccctgc gcatcgtcgc cgacgacctc gtcagcgcgc tgcgccgcgc
    18301 ggcacccggc ctgcactccg ccgatcccgc ggggtacgcc aacgccgtcg cacacgcacg
    18361 caccgcgcaa ggcctgctgc gctaccacgc cgccatggcc agcactgggc ccgaccgcgt
    18421 cgcgatcatg ctcagcgtcc gcaccgagat gatggccgac aacctgcacg cgatcgtcgc
    18481 cgcggagcag ggacgcgggc ccacgctggt gttcgcgcac aacgtccacc tccagcgcgc
    18541 acagcccggc acggcgatcg gcgacgtgag ctggtgcagc gccggggcgc tcgtcgaact
    18601 caccatgggg gagcggtacg cgttcgtggc caccgacgcc aaccccgcca gcgatccggg
    18661 caccctccaa ggggccttgg ccggggcgac cacacgccgc gcgctgttcc ccgcggcgga
    18721 cctgcgcgcc gcgctcgctc cgtcgatcgg caaggggcag ccgatcgtgc ccggccacct
    18781 cccgctcgac ccggcggagc tggccggtgc cgacgcggtc atcttcatcg ccgacaccga
    18841 cggaaaacgc caccagtact ggtaacgggc ctacccgatc catccatagt ggactcaggg
    18901 gcgcctgcgc aggtacagat cgcgcagcag agcgatttcc gcgccgtggt ggatcacctc
    18961 gcggtggatg tgcagcacca gcgcgggcag cggtcgatcc gcgaacggcc cttccgccgc
    19021 gcctccgacg cgggccaagt cgacggggga gagcgcccgg agcccggacg accacgcgtc
    19081 gtaagccgca tcgagctggt tcagcgccgt tgcggcggtt gcggcgaacg ggaacgtgtc
    19141 gtactggacg ggaggaccgc cgaactgcgt ctcggcccgc ttgccgagga cgtggacggt
    19201 gaggtgcgcc atccgccagg cgatcgtggt gaccggcgcc ggttccggcg tggggaacgc
    19261 gtagtcgacg gtgagccgcc cgccgccgat ctcgctctcc tcgcggcgcg gccgcagggt
    19321 ccagcagccg gggaccggtt cccagaagta ctcctcgtcg ctcaggccgg ccagccgcgg
    19381 cctgagccgt tcacgccagt gccagtccag ctgatcgccg agctccgcca cccagtcgac
    19441 gtccaccacg gatccacccc cgagttcgta cgcgtcagaa cgcgcgatga tactgccgcg
    19501 gccacgaccg gtgcggctcg gcgtcgagcg cgcgcagtgc ccagtacggg tcgcgcagca
    19561 tcgccctgcc gaccaacacc gcatccacca gatccgggat cgcttcgtcg aggtggcgag
    19621 cttcggaaac cagtcccgat gccgcggtga gaacccccgc cgcgcgaaac cgcggcccgt
    19681 attcggcgtt gtgcaacggt ttctcgatgc ggagggcccc cggggtcagc gcgccggaac
    19741 tgatgtcgat catgtcgacg cccgcccgcg ccatccggct cgcgacggac gccgcctcgt
    19801 ccgcggtcag gccgccctcg tgcagatccg cggcgggcag ccggacgatg accggcttgt
    19861 ccgccggcca tcccgcgcgg atcgcccgca ccatctccag cgggaaccgc atccgccgct
    19921 ccagatcgcc gccccactcg tcgacgcggt gatttgccag cggggaaagg aactcgtgga
    19981 gcaggtatcc gttcgcgccg tgcagttcga cgacctcgta gcccgcgcgg tgggcgttgc
    20041 gggcggcacg ctcgatgtcc tcgagcaccc gcgttccgtc ctttgtggtc atttcggccg
    20101 ggacaccgag cccggcgaac gggatcgggg agggcgcgag tggccgccac ccgccgtcct
    20161 cggggccgat cgggcgccgg gtcccggcgt tgtcccacgg cacgccgtgc gagctcttgc
    20221 ggcccgccgc gccgagctgg accgctggaa ccgacccgat ggccctgatg gccgccgcca
    20281 gccgccggtg cccgcgcacc tggtgttcgg accacagccc gagatcccgt ttcgtggtgc
    20341 gcatatcggg ggagacgccg gtgcattcga ccatcaccat gccgacgccg cctgccgctc
    20401 tggccccgta gtgggcgagg tgccagtcgg tgggggcgcc ggagccgtcc gcggagtact
    20461 ggcacatggg ggagagccac acccggttgg gcagcaacga ctcccggaga cgcaatgcgg
    20521 tccatgccgt ggatcccgtc gtcatcggcc accttttccg ctgggtgccc cgtcccgcac
    20581 ggggtcgtcg ccgaccacgg tacatcgaac atcatcgaac ttcgaatcat gttaaactgc
    20641 gcacatgccg cggcagcccg agcatcccga tctcgaagac gtgcaactcg cgcgagtgtt
    20701 ctccgcgctg ggggatccgg cgcggctgcg catcatgacc gtgctcgccg accgcacgga
    20761 gcaccagcgc gaggagttca ccgtggacgt cggcccgtcg acgctgagcc accacatgaa
    20821 gatcctccgc gaggcaggac tgacgcatca caggttcgag ggcacccgct gcttcgtctc
    20881 gctgcgcgcc gacacgttcg atcgcttcgc caccgtcttg gacagcacgc tgcagctact
    20941 cgcgaccgac caaggctgaa gcagaggcct tgcctgcacc aggaagcctc gtcacatctt
    21001 acttaacata atgtacatta tcggcattag gttgccggtg gtcgcgaacc cggccgaaca
    21061 ccagaatgcg gcgtggccgg agtcagctcc ggccacgccg caccactgct cagcgcgcgt
    21121 ctgccgctac ggcatcggcg cgccgttctc ggcgtagatc gcccaggtgt tgttcgactc
    21181 ccagtagcag ttgtaaccgg ggtgcacctg gaacaggtcc acgtagcggt agctcgcggt
    21241 gccgacgcac gtctgctcgt cccacggcgg gttgccgcgt tcgatcaggc agtaggcgta
    21301 ctggcaggtt cccccttgtg gtgcgacggg tgccgccgag gcggtgcccg tcgcacccgc
    21361 gaccatcagg cccgcggctc cagccgccgc gagtgccgcg ctcgccattt ttcgcatgcc
    21421 gctcatgtcg tccttccaac gcccccaggg gcatttacca tcgcgttgga tcacgttcgt
    21481 gatcttggac aacgtagcgc aggcatgttc gacattcacc gacaatggtg aagttcagcg
    21541 agaaccctcc tctcgctacc ccccagctcg gcgttgtttc gtcaccgtga cgtttctacc
    21601 gtgcgtggct ggacgtcgga ttagcgaagt tgttcgaggt ccttggctgc ttcggccaac
    21661 tcggccgcca tccgccggag ttcacccggc tccgcgccgt cgtccgccgc ggtcaccacg
    21721 tcctccgcgg cacagcggag ctggaacaac cggtcctgga gttcggcgat ctcggtggcg
    21781 gacagcacga cggcgtcctc gggcaggccg gtccgctgca cggcggccct gcgctcgtag
    21841 gcgcgctggc ggcacgactg gccgcagtac cgcctgcgcc tgccgatgtt cgcgccctcc
    21901 ggcaggtgca ggccgcacca gccgcagtgc cgccccgacc gcttccggtt gtgccccgtt
    21961 tcgtcaagtg acgaatcggc gcgctctgcc agtcctctca cgaacacgac cctaaccggc
    22021 catgctcagc tcacgccgcg gccacgccga caaggcacac tggacacgtg acccagcccc
    22081 atccgtacct cgccgaccct cacccccgcg cgttcgtgca ccgcgggtgg catctcgatg
    22141 agctggcggg actggagaac tcgctgcccg cgttccggcg tgccgtcgac gaaggcttcc
    22201 ggtacctgga gaccgacgtg cacgccagct cggacggcgt cgtcgtcgtg caccacgacg
    22261 ccacgctcga ccgcacgacc gacggcaagg gcacgatcgc gtcgcagagc tggcccgcac
    22321 tgagcaaggt caagatcggc gggaaggcgc cgctctcacg gctcgaagac ctcctcgagg
    22381 aacttccgaa cgcgtgcttc aacgtcgacg tcaaaacgga cgccgcggtc gagccgttcc
    22441 tgcgcacgct cgcgaagacg aactcctacg accgggtggc cgccgcggcg ttctccgacg
    22501 gccgccttgc gaagctgcgc aagctcgccg ggccgcgctt gctgacgtcg atgggtcccc
    22561 gctccgccgc cgcgctgtgg gcgcggggcc tcgctcccct actgccgctg ggtttcctga
    22621 ccgcgggcgc gatggcgcag gttcccatcc ggcagggctg gctgaccatt gtggacaaag
    22681 cgttccttcg cgcggccggg cgcgccggca tcgaggtgca cacctggacg atcgacgacg
    22741 caccggtgat gcggcggctg ctcgacctcg gcgtgcacgg catcgtcacc gaccggccgg
    22801 acgtccttcg cgacgtgctc accgagcgcg gcgcgtggca tccggccggt tgaccgcggt
    22861 taccgcggcg gtttgccctc ccaggccgcc ttccaggtct tcggcccgag ccgtccggag
    22921 tcgttgatcg cgttcacgcg ctgcaggtcc agtacggcgg tcttggtctt ttcgtagtag
    22981 cacccggtgc cgctgaagcc gtatccgaag gcgttcatcc gcagttggaa cgccttcaac
    23041 gctggtgcgc agtcaccgta ggcgtacacc acgcccggcc acgcgggctt cgggccgccg
    23101 ggcggtgccg ggggcttcgg cgcgggcggg acgggtggga gcggcctgcc gccgatgtag
    23161 gcggattcgt ggtagctggg cgtccgcttg gtgcgcgcgt cccggtcgtt ggagaacccg
    23221 agcatgccgg cgcattccca cggctgccag ccgcgcatgc ggtacaggta gagcgcgcgg
    23281 aagtcctgtt cggcaggact cgcctggtcc ggccgtccgc tgccgcccac gctctgccag
    23341 gtggcgaggt tgaactggta ggcgccgtag tagccgttcc cggtgttgat gtcgtaccgg
    23401 ccgctcgact cgcacatccg cagcttcgcc cacagccctg cactggggtc ggccgaagcc
    23461 ggtgtgctga cggcgatctg gaaccccaga acgccgacgg cgaggagaag aagcctcgcc
    23521 actcccctgg tcacgccccc gcgacggagt ttggtcatga gagcacacta agtattcgcc
    23581 ccataggcca caagagtcac agaggttaaa gccagcatca cacaccacat gggggatgcc
    23641 gagaagcgac acgcccgctt ctggtacccg ttttcctcgg cgtggcgaca tatgccccct
    23701 accggactta acggacagtc ctgtcgtgaa acgggtctcc atgcgcggga ccagcgagta
    23761 tggtcccggc gtgaggtgag gcccgatgtc cccgacgccc gaaatcgcgt cagcgctgcg
    23821 cgatggcccg ttcagcaagg cactggaact ggccgtgcgc gcgagcgggc tgagcctccg
    23881 gcagctgcag aaccggctct tcgccagcgg cgtgcgagtc agtgtggtga cgctcagtta
    23941 ctggcagagc gggcgaagcc taccggaacg gccgcagtcg ctccgtggtg tcgacgtgct
    24001 cgaagtggtg ctcgacctgc cgcccggttc gctgcgcggg ttgctcgggc ctcgtcggcc
    24061 ccgaggcagg ggcgtgtggt cggacaaacc ggtcgatcgc ctgtgccggg cgtgggacta
    24121 ccccgccttc ctgccctcgt tactcgacgg gttcggtgat cgcaggctcc ggccggtcac
    24181 gaggttgggc ttgcgggaga ccctgcacgt gggctccgat cggtgtgcgc ggcggatggt
    24241 cgtcgaggag ttcatcgagg cacgccacga cgggacggtg tcggtcacca tcgcgaaccg
    24301 gagcaggcgg ggcgctcgtc cgctccaggt gacggcgacg agccggtgcc ggcccggtcc
    24361 gacgctcgaa ctgggcgccg agggcttttc ggtggtggaa ctggtcctcg accggccgct
    24421 cgctcgcggg cagcgagcgg cgatccggta tcagctcgaa taccccgatc cggtgctcgc
    24481 cgagcatcac catcgccggg tcgccgagcc ggtggccgcg tatcgcggcc gcgtggtgtt
    24541 ctccgctcgg gagaccccga tccggtgcga gacatggcgg aggcgttcgt gtgacgggct
    24601 ggtgagcggg atttcc
//
