LOCUS       NZ_CP059997            20558 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6412855
            Orig. end                         :: 6433413
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20558
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="29"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20558
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20558
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10558](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10558
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     misc_feature    338..352
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.36"
                     /tool="antismash"
     misc_feature    994..1012
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.81"
                     /tool="antismash"
     misc_feature    1285..1298
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.79"
                     /tool="antismash"
     misc_feature    1618..1632
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            1776..3149
                     /locus_tag="HUW46_RS30850"
                     /old_locus_tag="HUW46_06123"
     CDS             1776..3149
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804766.1"
                     /locus_tag="HUW46_RS30850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06123"
                     /product="phosphotransferase"
                     /protein_id="WP_254125055.1"
                     /sec_met_domain="APH (E-value: 6.6e-06, bitscore: 25.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADIERFVAGLAAELPAWLPGQRWFAGKDRPVTGVVPLATTVLI
                     DGDPLLLHVVVEVAQGDRREPYQLLVGRRSHPPEVSASSWIGELAGYEASGDADLTAIL
                     LDLMARGERVGSLVFAHEPGVELAVELRARPITAEQSNTSLVYGGQYILKLFRKLSAGE
                     NKDLLLHRALQAAGCEHIAPTLGSITGELAGKPVTIGMLQQFLPDAVDGWAMATTSVRD
                     LMAEPELGPDEVGGDFAGEAERLGSAVAAVHADLARALGTEPLDDHELARTVKGMTDRL
                     DEVAARVPGLVPHVPGLRAAFEALSSAPANSIAMQYIHGDLHLGQVLRTVNGWLLLDFE
                     GEPAAPVEERHALRSPLRDVAGMLRSFDYAAQQLLVGQDADPLLTERALEWARRNRAAF
                     CDGYAKAADESIGDPRDHGALLRAFELDKAVYEVAYEHANRPDWLGVPLSSIASITRE"
     gene            3154..5352
                     /gene="glgB"
                     /locus_tag="HUW46_RS30855"
                     /old_locus_tag="HUW46_06124"
     CDS             3154..5352
                     /EC_number="2.4.1.18"
                     /GO_function="GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0043169 - cation binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420587.1"
                     /locus_tag="HUW46_RS30855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06124"
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="WP_215542281.1"
                     /sec_met_domain="CBM_48 (E-value: 4e-22, bitscore: 77.4,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-10, bitscore:
                     40.3, seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase_C (E-value: 1.3e-22,
                     bitscore: 79.1, seeds: 246, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTANLPDSAPPAEDIDRLLAGSHHDPHGVLGVHGGSSSGGTVVAR
                     ALRPGAKAVAVVAGTRSFPLDHVVDGLFSGALPEHPGDYRLEVSFDSHTETTDDPYRWL
                     PTVGELDLHLIGEGRHEQLWDALGAHVRSYDTPHGTVEGVSFAVWAPTARGVRVIGDFN
                     GWEGRAHPMRSLGSSGVWEIFVPGVGAGACYKFRILGQDGNWHEKADPMAFATEKPPAT
                     ASVVTSSSHVWGDDEWTAAREVTNWADAPMSVYEVHLGSWRPGLGYRELAEQLADYLAE
                     TGFTHVELLPITEHPFGGSWGYQVTSYYAPTARFGSPDDFRSFVDILHRRGFGVLMDWV
                     PAHFPRDAWALARFDGTPLYEHADPRRGEQPDWGTYVFDFGRNEVRNFLVANALFWLEE
                     YHLDGLRVDAVASMLYLDYSRKDGEWLPNQYGGRENLDAVRFLQELNATVYKRHPGVVM
                     MAEESTAWPGVTRPTHLGGLGFGFKWNMGWMHDTLRYLGHEPVHRAYHHNEMTFSLVYA
                     WSEHFVLPLSHDEVVHGKGSLWERMPGDDWNKAAGVRSLLAFMWAHPGKQLLFMGGEFG
                     QRAEWSESRSLDWHLLEEPLHRGVRELTRELNGAYRQLPALYSQDTSYEGFQWIDANDA
                     NGNVLSFLRIGKDGSRLACVANFAGVPHHDYRVGLPSAGRWREVLNTDAEAYGGSGVGN
                     LGEVEAVTEPWHGQPASAVLQLPPAGVLWLAEEPDSVR"
     gene            5407..6555
                     /gene="glgA"
                     /locus_tag="HUW46_RS30860"
                     /old_locus_tag="HUW46_06125"
     CDS             5407..6555
                     /EC_number="2.4.1.21"
                     /GO_function="GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="glgA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684038.1"
                     /locus_tag="HUW46_RS30860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06125"
                     /product="glycogen synthase"
                     /protein_id="WP_215542282.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-31,
                     bitscore: 108.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGLLTREYPPDVYGGAGVHVEFLARELRSLVDLDVHCWGADRD
                     GAHGHTDAHGYAEAAFSTMDIAVSMAAALSGHELAHSHTWYANLAGHLAKLHHGIPHVV
                     TAHSLEPLRPWKAEQLGGGYRISSWIEREAYESADAIIAVSGGMRQDVLDAYPAVAPDR
                     VHVVHNGIDTALYQPREDPAVLAKHGIDPDRPYVLFVGRITRQKGVPHLVRAGAALDEG
                     TQLVLCAGGADTPELDVEFRGLVADLQRNRTGVHWIPEMLPRDEVVRLLTHAAVFACPS
                     VYEPLGIVNLEAMACGTAVVASDVGGIPEVVEDGKTGLLVHYDENDTAAFEAGLAAGIN
                     ELVGDPGRAAEMGAAGRARAVGEFGWAAIAERTAGIYGGLRD"
     gene            6548..7765
                     /gene="glgC"
                     /locus_tag="HUW46_RS30865"
                     /old_locus_tag="HUW46_06126"
     CDS             6548..7765
                     /EC_number="2.7.7.27"
                     /GO_function="GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076484.1"
                     /locus_tag="HUW46_RS30865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06126"
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="WP_215542283.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.8e-09, bitscore:
                     35.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDGSDVLGIVLAGGEGKRLMPLTADRAKPAVPFGGVHRLVDFVL
                     SNLVHGGVRRICVLTQYKSHSLDRHISTTWRLSSLTGEYVTPVPAQQRLGPRWYQGSAD
                     AIHQSLNLVHDEQPAYIAVFGADNIYRMDPRQMIDAHIEAGAGVTVAGIRVRREEASSF
                     GVIQTADGSAIDAFLEKPTDPPGLPDSPGESYVSMGNYVFTTQVMLDALEKDARNPSSH
                     HDMGRDIIPALVETGQAHVYDFTGNEVPGETERDHGYWRDVGTIDSYYDAHTDLISTYP
                     IFNLYNRRWPILAHPAQRAAAKFVEGGTANQSIVSNGCIISGAQVVDSVLSPDVYVENG
                     AVVQGSVLLDGVRVGKGAVVRRAILDKNVVVPPGAHIGVDLARDREHYHVSEGGIVVLG
                     KGARAI"
     gene            7807..8664
                     /locus_tag="HUW46_RS30870"
                     /old_locus_tag="HUW46_06127"
     CDS             7807..8664
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659586.1"
                     /locus_tag="HUW46_RS30870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06127"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_215542284.1"
                     /transl_table=11
                     /translation="MSDRNQPPQQQDPPGTSEEMDPRPRDRMTGYVGRGLFTGLRALIT
                     GGDSGIGRAVAVAFAKEGADIAIAYLNEHSDAERTAGLVRAEGRQCVLLPGDLAGGEHC
                     RDVVEQTVRLLGGLEILVNNAATQWPVDSPEELTEDQWMHTFDVNIHSYFRVTAAALPH
                     LRDGSVIINTGSVNGLRGNKSLIDYSATKGAIHAWTYAMAQALADRRIRVNCVAPGPVW
                     TPLIPATFPPEKVEKFGLQVPFGEAAHPDDLAPSYVFLASNQLSGYYTGEVLAALGGET
                     TPGG"
     gene            complement(8665..8862)
                     /locus_tag="HUW46_RS48465"
                     /old_locus_tag="HUW46_06128"
     CDS             complement(8665..8862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226945.1"
                     /locus_tag="HUW46_RS48465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06128"
                     /product="DUF2795 domain-containing protein"
                     /protein_id="WP_254125057.1"
                     /transl_table=11
                     /translation="MRNYQDFLTDVEYPCRRDEILRRAAANGAGDNVLGRLSTLPERDY
                     DCLDTVHSELSEEFGRENRG"
     gene            9049..10011
                     /locus_tag="HUW46_RS30880"
                     /old_locus_tag="HUW46_06129"
     CDS             9049..10011
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (61-166). E-value:
                     4.1e-14. Score: 44.7. Matches aSDomain:
                     nrpspksdomains_HUW46_RS30880_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="HUW46_RS30880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06129"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_215542286.1"
                     /sec_met_domain="PF00561 (E-value: 3.7e-10, bitscore: 39.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.9e-11, bitscore:
                     42.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.4e-08, bitscore:
                     33.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALERQVAAGLSVLLGLSAATGVLTRRSGRRDRKRRYPVHRRAD
                     GTLVEFAAHLPDDARYVVLLEAGLGMPHEYWDWVCAELPGDAGWFRYHRPGYGLSTPRP
                     EFALREHFDLLDELRNAHFPERPVVLVGHSLGGYLAAAYAAFHRGTDRGIRRLVLVDST
                     NIRQVHRTAGSAPDRWARQTMVLERIFALTGLGALRPAANRRRTYADEVNRTHRAFLSE
                     YRSWATAHREYRASQDFPELGDVGVPMDVVTVSNGLASSAAHRSAQAELLDLSTESEHH
                     FVQDAEHESVVATREHAAEVVRVIAAGMRSEVEEVRDAR"
     aSDomain        9232..9546
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS30880_Abhydrolase_1.1"
                     /evalue="4.10E-14"
                     /label="HUW46_RS30880_Abhydrolase_1.1"
                     /locus_tag="HUW46_RS30880"
                     /protein_end="166"
                     /protein_start="61"
                     /score="44.7"
                     /tool="antismash"
                     /translation="VVLLEAGLGMPHEYWDWVCAELPGDAGWFRYHRPGYGLSTPRPEF
                     ALREHFDLLDELRNAHFPERPVVLVGHSLGGYLAAAYAAFHRGTDRGIRRLVLVDSTNI
                     R"
     CDS_motif       9418..9480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS30880_0001"
                     /evalue="1.20E-06"
                     /label="NRPS-te1"
                     /locus_tag="HUW46_RS30880"
                     /protein_end="144"
                     /protein_start="123"
                     /score="21.1"
                     /tool="antismash"
                     /translation="PERPVVLVGHSLGGYLAAAYA"
     gene            10001..10558
                     /locus_tag="HUW46_RS30885"
                     /old_locus_tag="HUW46_06130"
     CDS             10001..10558
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS30885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_06130"
                     /product="hypothetical protein"
                     /protein_id="WP_215542287.1"
                     /sec_met_domain="cypI (E-value: 5.9e-26, bitscore: 90.6,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGERWKTAAVTTGLATWLVVTAAGQLPDTRFDGLLGKGAWRIPV
                     PNWRFFGPNPGTKDVHLLYRDVSASGATPWEQVPVTGDRPWYALVWNARNRSPKALFDS
                     LQSITTFAATVRGDLDRIEKSFGYGFLAEYVREHLPHDPVAEATQFLLMESFPSRGDDL
                     EIIPVFASREIGLDDVKRELCE"
     gene            10597..10773
                     /locus_tag="HUW46_RS30890"
                     /old_locus_tag="HUW46_06131"
     CDS             10597..10773
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS30890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_06131"
                     /product="hypothetical protein"
                     /protein_id="WP_215542288.1"
                     /transl_table=11
                     /translation="MHNDVVATYANENLPSVSPGFVSTGDDEISYFCTSQAYLTNFYDS
                     FFNDIPATFAVNS"
     gene            10886..11752
                     /locus_tag="HUW46_RS30895"
                     /old_locus_tag="HUW46_06132"
     CDS             10886..11752
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_06132"
                     /product="hypothetical protein"
                     /protein_id="WP_215542289.1"
                     /transl_table=11
                     /translation="MAIGRQHDVVARRVASLGTLVSALEMLSQSARFEKGELLSTQLGK
                     TKPKFAKRFPRLVDALSSKKASVGLYAAQAAASAATIAWPRSRRVQFAGAAALAAIGAT
                     NRARNPFGGDGADQLQQVINVTFAATATLKDREKARDLALRTLALETTISYVASGLVKV
                     VSPVWLHGEAFEGIIRTRNYGDPRVHRLVTRFPLLGKLVSWSTIAAELGFPVVFVLPLP
                     AARAYLGMMTSFHLGIGQFMGLNRFVLAFGATHPAILHVLSERKSRSTPRERGVGKEER
                     TSEQREN"
     gene            11752..11934
                     /locus_tag="HUW46_RS30900"
                     /old_locus_tag="HUW46_06133"
     CDS             11752..11934
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS30900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_06133"
                     /product="hypothetical protein"
                     /protein_id="WP_215542290.1"
                     /transl_table=11
                     /translation="MRNDTITDFANDHLGVVTPGLVGSGEDAPPVFYVTSASASLMVPT
                     VTDATVQTIVISAAG"
     gene            complement(12069..13322)
                     /locus_tag="HUW46_RS30905"
                     /old_locus_tag="HUW46_06134"
     CDS             complement(12069..13322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643541.1"
                     /locus_tag="HUW46_RS30905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06134"
                     /product="M28 family peptidase"
                     /protein_id="WP_254126658.1"
                     /transl_table=11
                     /translation="MGQAVAAPAAPVAPAPHAVAAPDISLANVRGHLSQLETIARQYGG
                     SRTAASGGYAASVSYVEQKLKEAGFTTSRQTCTSCSGQSQNLIAEWPKGDANQVIMLGA
                     HLDSVSAGPGINDNGSGSAAILEVALTLAKTNPEMAKRVRFGWWADEESGLRGSRFYVN
                     NLPSSERSKIKAYLNFDMIASSNWGHFVYDDVASIKAVFDEYFATLNVPTEGDSEGDGR
                     SDHASFKSAGIPVGGLATGAGDIKSAAQQRKWGGTAGAAFDNCYHRSCDTLSNLKDVPM
                     DRNSDAIAYAVWKLAVGSSTPPGDRVFTNSTAYPITDYGTVNSPVSATTAGAANSPVQV
                     KITASHTCAEDLRISLTGPSGRSYSVKPTGNAPCTQFGTRDFSVPVTTENAAGTWTLVV
                     YDAFAGDTGTLTSWALTV"
     gene            complement(13460..15559)
                     /locus_tag="HUW46_RS30910"
                     /old_locus_tag="HUW46_06135"
     CDS             complement(13460..15559)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009072865.1"
                     /locus_tag="HUW46_RS30910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06135"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_215542291.1"
                     /transl_table=11
                     /translation="MTQRGLRSGLAAIAGLAMTMAMPAIPATAAPAAPPAQPASPEAAA
                     ISAADQAAAIGVDKLSKGANEAFHRLGVTPGGAGLFYVSYERTYHGLPVIGGDAVVVAD
                     GVGHVRDTSAAATADIKVGTKPGISADRAASIARGQLSTVDSVSSPNLVVVGGATPKLA
                     YEVVVKGRGANLPSNLHVFVDGATGAVLDKRDDVKTLAPRATGTPASTPPAPLGSGNSY
                     YVGNVTIDTTGSGSSYSMRDPGRSGISCGREGGSVFTGNDDAWGNGSGTDLETGCVDTL
                     FAVQHEWNMLKDWLGRNGIDGNGRGFPASVGLNDVNAYWDGSSTHFGHSQDNRRQATSM
                     DVVGHEFGHGVFQNTPGGAGSGNENGGLNESTGDIFGALTEFYTNNAKDTPDYEVGEGV
                     NLVGKGPIRYMYDPSKVGDPNCYSSSIPNTEVHAAAGPQNHWFYLLAEGTAPTDGQPTS
                     PTCNNSSITGIGIQSAGKIFYNALLKKTSSWRTSSARKATLEASLTLFPNSCTEFNAVK
                     AAWNAVSVPPVSGEPTTCNQQPGKNDYSVSLSPTSGTVKPGESATVTVGTTTTNGTAQS
                     IKLTASGLPTGATAKFEPESITSGGSSKLTITTAATTPNGTSKVTINADGVEVDHTVQY
                     DLTVGSGNPPTGCDGVAAWDANTLYVPGDVVSHNGHKWTSNWYSAGSEPGSPGSWYVWK
                     DSGAC"
     gene            complement(16348..17607)
                     /locus_tag="HUW46_RS30915"
                     /old_locus_tag="HUW46_06136"
     CDS             complement(16348..17607)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="HUW46_RS30915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06136"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_215542292.1"
                     /transl_table=11
                     /translation="MFETSPSLAPQQDELWRLDAREVASLLREEFVSWWQQEARIHRMI
                     AHLDNGGARDLGYTSVAGLVADIARCTGPEVKRLVKRALVTNPGQGIDGTEIPAAAPLV
                     GDAAREGAISPEHVDKIVRVLEKIPATTPVEDREFAERSLVELARKAGTSQISKLGKEL
                     LGYLDPDGPEPRDTPEPTRALHFHQRKDGSAKFDGYLDPISAAKTLALLDPLAQSQPND
                     PSGNPLRRGQAERYGDAFMEMVALAASHPESPNRSGGRADLIVTIPLADLKAELGKACL
                     DMVTDITASEARILACDCRIIPMMLDGKGQPLEVGRAKRLVTEAIRYMLAMRDKGCAFP
                     GCSRAPRHCEAHHVVPWAHGGLTEVGNLVLLCGHHHRLLHRSDWTLRMVNGLPEFTPPD
                     FIDPWRRSRTNSHTAQPRAA"
     misc_feature    17627..17642
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(17689..17702)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.54"
                     /tool="antismash"
     gene            17884..18567
                     /locus_tag="HUW46_RS30920"
                     /old_locus_tag="HUW46_06137"
     CDS             17884..18567
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058614.1"
                     /locus_tag="HUW46_RS30920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06137"
                     /product="response regulator transcription factor"
                     /protein_id="WP_215542293.1"
                     /transl_table=11
                     /translation="MTSRTAPRILLVEDAEAIRVSVEAALGTAGFEVRARADGEAIEQD
                     LVGFRPDLVVLDVLLPGRDGFELLSLIRRHSAAGVVMLTARDGVEDRLRGLGEGADDYV
                     VKPFVLAELVARVTAVLRRTGRTKPTVEIGDLVVDAEAGMALYRGERIDLTATEWKLLS
                     HLAAHRDRVLSKTQILAAVWGYDDYAENLVEVNVSTLRRKLEQHGPRILHTVRGQGYVL
                     RGDVG"
     gene            18564..19904
                     /locus_tag="HUW46_RS30925"
                     /old_locus_tag="HUW46_06138"
     CDS             18564..19904
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058612.1"
                     /locus_tag="HUW46_RS30925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_06138"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_215542294.1"
                     /transl_table=11
                     /translation="MTGLRTTSLYRRVTTTALVVLAVVLVVLGFVVSAVFRAQAERDVN
                     GLLAGRVQLAQQLAKQGAPPQNLVRRVETRGVEGRLTLTDGTVFGAPPRPAEARLRQVK
                     ATLSGRGQVNGAALTLTADESIVAGAESTLRWVLLFTGLAAVAVTAAALLVGVRIALSP
                     LDAMTGLARSIVTGRRGGRLAPSSAKTELGRAASAFDDALDALEGAERAARASEERTRR
                     FVADAAHELRTPIAGVQAAAEAVLQQGPDADPALTERLHLLLARESQRAGKLVSDLLDL
                     AHLDAGVRLDAAPVALLPLAQAQADRARLLAPELTVEVSGPDAVVLGDSDRLTQILANL
                     VDNAVRAMAGHGTLTLTVTESGVVVSDTGPGVPAEDVERIFDRLVRLDDARGQSGSGLG
                     LAIARGFARAHGGDLRYEPSAGASFVLYGLSKPDSQAGSSSPSSRPE"
     misc_feature    complement(20429..20438)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ctcggcctcg acggcgtgcc gcacacgggt gaggcgatca ccgaagacgg catgctggtc
       61 gagccgcagg ccgaggactt caagtccgcg cgggaggcgc cgagcgaccc gcactggttc
      121 aagggcgcgg tgttctacga ggtgctcgtg cgcgcgttca ccgattccaa cggcgacggc
      181 acgggcgatc tccgcgggct cgcgagcagg ctcgactacc tcgaatggct cgggatcgac
      241 tgcctgtggc tgccgccgtt ctacgcttcg ccgttgcgcg acggcggcta cgacatcagc
      301 gatttccgcg cggtgctccc ggaattcggc agcgtcgagg atttcgtgtt cttgctcaac
      361 gaggcgcatc gccgcgggat cagggtgatc accgatctgg tgctgaacca cacctccgac
      421 gcgcacccgt ggttccagca gtcgcggtcc gatccggacg gtccctacgg cgactactac
      481 gtgtggagcg acgacgattc gcggtacgcc gacgcgcgga tcatcttcgt ggacaccgaa
      541 tcctcgaact ggacctacga cccggtgcgc gggcagttct actggcaccg gttcttcacc
      601 caccagccgg acctgaacta cgagaacccc ggtgtgcagg aagcgatgct ggacgtgctg
      661 cggttctggc tcgacctcgg catcgacggg ttccgcctgg acgccgtgcc gtacctgttc
      721 gagcaggagg gcacgaactg cgagaacctc ccgcgcacgc acgaattcct gaagcgctgc
      781 cgcaaggtcg tcgacgacga gtaccccggc cggatcctgc tcgccgaagc gaaccagtgg
      841 ccttcggacg tggtggagta cttcggcgac ccgctcaccg gcggcgacga atgccacatg
      901 gcgttccact tcccgttgat gccgcgcatc ttcatggccg tgcggcggga atcgcggttc
      961 ccgatttcgg aaatcctcat gaagacaccg gaaattccga gcggcacgca atggggcatc
     1021 ttcctgcgca accacgacga gctgacgctg gaaatggtca ccgatgaaga gcgcgactac
     1081 atgtacgcgg aatacgcgaa ggatccgcgg atgaaggcga acatcgggat ccgccgccgc
     1141 ctcgcgccgc tgctggacaa cgatcgcaac cagcaggagc tgttcaccgc gatgctgctg
     1201 tcgctacccg gttccccggt tctgtactac ggtgacgaga tcggcatggg tgacaacatc
     1261 tggctcggcg accgcgacgc ggtgcgcacg cccatgcagt ggaccccgga ccgcaacgcc
     1321 gggttctcgg tgtgcgatcc cggccggatc tacctgccgg tgatcatgga cccggtgtac
     1381 gggtaccagg gcctcaacgt ggaggcgcag tcgaacaacg cgtcctcgct gctgaactgg
     1441 acgcgccgga tgatcgaggt gcgcaaggag caccacgcgt tcgcggaggg ggagttcatc
     1501 gacctcggcg ggtcgaaccc gagcgtgctc gcctacaagc ggcagtggtg gcggccggac
     1561 gggcggcagg acgtggtgct gtgcgtcaac aacctgtcgc ggttcccgca gccggtggaa
     1621 ctagatctgg gcgcgcaccg gttcagcacg ccggtggagc tcaccggcgg ggtccggttc
     1681 ccggagatcg gtgagctgcc ctacctgctc acgctgccgg ggcacgggtt ttactggttc
     1741 cagctggtcg agccggagga ggaggcggat acgaggtgag tgccgacatc gagcggttcg
     1801 tggcggggct ggccgccgaa ctgcccgcct ggctgcccgg ccagcggtgg ttcgccggca
     1861 aggaccggcc ggtcaccggc gtggtgccgc tggcgaccac agtcctgatc gacggggatc
     1921 cgctgctgct gcacgtggtc gtcgaggtcg cccagggtga ccggcgcgag ccttaccagc
     1981 ttctcgtcgg ccgccggtcg catccgccgg aggtgtccgc gtcgagctgg atcggcgagc
     2041 tggccgggta cgaagccagc ggggacgccg atctgaccgc gatcctgctc gacctgatgg
     2101 cgcgcggcga acgggtcggt tcgctggtct tcgcgcacga acccggtgtc gagctggccg
     2161 tcgagctgcg ggcgcggccg atcaccgcgg agcagagcaa cacgtcgctg gtctacggcg
     2221 gccagtacat cctcaagctg ttccgcaagc tcagcgccgg ggagaacaag gacctgctgc
     2281 tgcaccgcgc gctgcaggcg gcgggctgcg agcacatcgc gccgacgctc gggtcgatca
     2341 ccggggagct ggccggaaaa cccgtcacca tcggcatgct ccagcagttc ctccccgacg
     2401 ccgtggacgg gtgggcgatg gccaccacga gcgtccgcga cctgatggcc gagcccgagc
     2461 tgggcccgga cgaggtgggc ggcgatttcg ccggggaggc ggagcggctc ggcagcgcgg
     2521 tcgcggcggt gcacgccgat ctcgcgcgcg cactgggcac cgagccactc gacgaccacg
     2581 aactcgcccg caccgtcaag ggcatgaccg accggctcga cgaggtcgcc gcgcgggtgc
     2641 cggggctggt gccgcacgtg cccggcctgc gcgccgcgtt cgaagcgctc tcctcggcac
     2701 ccgcgaattc gatcgccatg cagtacatcc acggcgacct gcacctcggg caggtgctgc
     2761 ggaccgtcaa cggctggctg ctgctcgact tcgagggcga gccggccgcg ccggtggagg
     2821 agcgccacgc gctgcgttcg ccgttgcgcg acgtcgcggg gatgctgcgt tccttcgact
     2881 acgcggcgca gcagctgctc gtcggtcagg acgccgatcc gctgctcacc gagcgcgcgc
     2941 tcgaatgggc gcgccgcaac cgcgccgcgt tctgcgacgg ctacgcgaaa gcggccgacg
     3001 agtcgatcgg cgaccctcgc gaccacggcg cgctgctgcg ggccttcgaa ctcgacaagg
     3061 ccgtctacga ggtcgcctac gagcacgcga accggccgga ctggctcggc gtgccgctgt
     3121 cttcgatcgc ttcgataacc cgggagtagc accatgaccg cgaacctgcc ggattcggcg
     3181 ccaccggccg aggacatcga ccggctactc gccgggtcgc accacgatcc gcacggcgtg
     3241 ctcggcgtgc acggcgggag ttccagcggg ggcaccgtgg tggccagggc gctgcggccg
     3301 ggcgcgaagg cggtggcggt ggtcgcgggc acgcgctcgt tcccgctcga ccacgtcgtc
     3361 gacggcctgt tctcgggcgc gctgcccgaa caccccggtg actaccggct cgaagtttcc
     3421 ttcgactccc acaccgaaac caccgacgac ccgtaccgct ggctgcccac ggtgggggag
     3481 ctggacctgc acctgatcgg cgagggcagg cacgaacagc tgtgggacgc gctcggcgcg
     3541 cacgtgcggt cgtacgacac tccacacggg acggtcgagg gcgtgtcatt cgcggtgtgg
     3601 gcgccgaccg cgcgcggtgt gcgcgtgatc ggcgacttca acggctggga gggccgcgcg
     3661 cacccgatgc gctcgctcgg ctcttcgggg gtgtgggaga tcttcgtgcc cggcgtcggt
     3721 gccggtgcgt gctacaagtt ccgcatcctg ggccaggacg gcaactggca cgagaaggcc
     3781 gacccgatgg ccttcgccac ggagaagccg cccgccacgg cctcggtggt caccagctcg
     3841 tcgcacgtgt ggggcgacga cgagtggacg gcagcgcgcg aggtgacgaa ctgggccgac
     3901 gcgccgatga gcgtctacga agtccacttg ggatcgtggc ggcccggcct cgggtaccgc
     3961 gaactggccg agcagctcgc ggattacctg gcggaaaccg gtttcaccca cgtcgagctg
     4021 ctgccgatca ccgagcaccc gttcggcgga tcctggggct accaggtgac ctcgtactac
     4081 gcgccgaccg cgcggttcgg ctcgccggac gatttccggt cctttgtgga cattctgcac
     4141 cggcgcgggt tcggcgtgct gatggactgg gtgcccgcgc acttcccgcg cgatgcctgg
     4201 gcgctcgcgc ggttcgacgg caccccgctc tacgagcacg cggatccccg tcgcggcgag
     4261 cagccggact ggggcaccta cgtgttcgac ttcggccgca acgaggtccg caacttcctc
     4321 gtcgccaacg cgctgttctg gctggaggag taccacctcg acggcctccg ggtggacgcc
     4381 gtcgcctcga tgctctacct cgactattcc cgaaaggacg gtgagtggct cccgaaccag
     4441 tacggcggca gggaaaacct cgacgccgtc cggttcctgc aggagctcaa cgcgaccgtc
     4501 tacaagcgac accccggcgt ggtgatgatg gccgaggagt ccaccgcgtg gccaggcgtg
     4561 accaggccga cgcatctcgg cgggctcggg ttcggtttca agtggaacat gggctggatg
     4621 cacgacacgc tgcgctacct cggccacgag ccggtgcacc gcgcctacca ccacaacgag
     4681 atgaccttct cgctcgtcta cgcgtggagc gagcacttcg tgctcccgct ctcgcacgac
     4741 gaagtggtgc acggcaaggg atcgctgtgg gagcgcatgc cgggcgacga ctggaacaag
     4801 gcggcgggtg tgcgctcgct gctggcgttc atgtgggcgc accccggcaa gcaactgctg
     4861 ttcatgggcg gcgagttcgg gcagcgcgcg gagtggtcgg aatcccgctc gctcgactgg
     4921 cacctgctgg aggagccgct gcaccgcggc gtgcgcgagc tgacgcgcga gctgaacggc
     4981 gcctaccggc agctgcccgc gctctacagc caggacacct cctacgaggg cttccagtgg
     5041 atcgacgcga acgacgcgaa cggcaacgtg ctgagcttcc tgcgcatcgg caaggacggc
     5101 tcgcggctgg cgtgcgtggc gaacttcgcc ggcgtgccgc accacgacta ccgggtcggg
     5161 ctgccctcgg cggggcgctg gcgcgaagtg ctcaacaccg acgccgaggc ctacggcggc
     5221 tccggggtcg ggaacctggg agaggtggaa gcggtgaccg aaccgtggca cgggcagcca
     5281 gcttcggccg tgctccagct cccgcccgcc ggggtgctct ggctggcgga agaacccgat
     5341 tctgtccggt aattcgccca tccgccagac tgcgttcgcc gggtgtgagt gcgtagggtg
     5401 cgggacatga agatcggcct gctcacccgg gagtacccgc cggacgtcta cggcggcgcc
     5461 ggggtgcacg tcgaattcct cgcccgcgaa ctgcgctcgc tcgtcgatct cgacgtgcac
     5521 tgctggggcg cggaccgcga cggcgcgcac gggcacaccg acgcgcacgg ctacgccgag
     5581 gccgcgttct ccacgatgga catcgcggtg tccatggcgg cggcgctgtc tggccacgag
     5641 ctggcgcaca gccacacctg gtacgcgaac ctcgccgggc acctcgcgaa gctgcaccac
     5701 ggcatcccgc acgtggtgac cgcgcactcg ctggaaccgc tgcgcccgtg gaaggccgag
     5761 cagctcggcg gcggctaccg gatctcgtcg tggatcgagc gcgaggcgta cgagtccgcg
     5821 gacgcgatca tcgcggtcag cggcggcatg cgccaggacg tcctcgacgc ctaccccgcg
     5881 gtggcgccgg accgcgtgca cgtcgtccac aacgggatcg acaccgcgct ctaccagccc
     5941 cgcgaagacc cggccgtgct cgcgaagcac ggcatcgatc ccgatcggcc gtacgtgctg
     6001 ttcgtcggca ggatcacccg gcagaagggc gtgccgcacc tcgtccgcgc tggcgccgcg
     6061 ctcgacgaag gcacccagct cgtgttgtgc gcgggtggcg cggacacgcc cgagctggac
     6121 gtcgagttcc gcgggctggt cgccgacctg cagcggaacc ggaccggggt gcactggatc
     6181 cccgagatgc tgccgcgcga cgaggtcgtg cgcctgctga cgcacgccgc ggtgttcgcc
     6241 tgcccgtcgg tctacgagcc gctggggatc gtgaacctgg aggcgatggc gtgcggcacg
     6301 gcggtcgtcg cgagcgatgt cggcggtatc cccgaggtcg tcgaggacgg gaagaccggt
     6361 ctgctcgtgc actacgacga aaacgatacg gccgcgttcg aagccgggct cgcggccggg
     6421 atcaacgagc tggtcggcga tccgggacgg gccgccgaaa tgggggcggc cgggcgtgcg
     6481 cgcgcggtcg gggagttcgg gtgggccgcg atcgccgagc ggacggccgg tatctacgga
     6541 ggtcttcgtg attgacggat ccgacgtact cggcatcgtc ctcgcgggcg gcgagggcaa
     6601 acggctcatg ccgctgaccg cggaccgcgc gaaacccgcg gtgcccttcg gcggggtgca
     6661 ccggctggtg gacttcgtgc tgtcgaacct cgtgcacggc ggcgtccggc ggatctgcgt
     6721 gctcacccag tacaagtcgc attcgctcga ccggcacatc agcaccacct ggcggctgtc
     6781 ctcgctcacc ggtgagtacg tcacgccggt gcccgcgcag cagcggctcg ggccgcgctg
     6841 gtaccagggc agcgccgacg cgatccacca gagcctgaac ctggtgcacg acgagcagcc
     6901 cgcctacatc gcggtgttcg gcgccgacaa catctaccgg atggacccgc ggcagatgat
     6961 cgacgcgcat atcgaagcgg gcgcgggcgt caccgtcgcg ggcatcaggg tgcgccggga
     7021 ggaggcgagt tcgttcggcg tgatccagac ggccgacggc tcggcgatcg acgcgttcct
     7081 ggaaaagccg acggacccgc ccggcctgcc ggactcgcca ggtgagtcct atgtgtccat
     7141 gggcaactac gtgttcacca cgcaggtcat gctcgacgcg ctggaaaagg acgcgcggaa
     7201 cccgtcctcg caccacgaca tgggccgcga catcatcccg gcgctggtgg aaaccggcca
     7261 ggcgcacgtc tacgacttca ccggcaacga ggtgcccggc gaaaccgaac gcgaccacgg
     7321 gtactggcgc gacgtcggca ccatcgacag ctactacgac gcgcacacgg acctgatctc
     7381 cacctacccg atcttcaacc tgtacaaccg gcgctggccg atactcgcgc accccgcgca
     7441 acgcgccgcc gcgaagttcg tcgaaggcgg caccgcgaac cagtcgatcg tcagcaacgg
     7501 ctgcatcatc tccggcgcgc aggtggtcga ttcggtgctc tccccggacg tctacgtgga
     7561 aaacggcgcc gtggtgcaag gctcggtatt gctcgacggc gtccgcgtcg gcaagggcgc
     7621 cgtggtacgc cgggcgatcc tggacaagaa cgtggtcgtc ccacccggcg cgcacatcgg
     7681 cgtcgacctg gcgcgcgacc gcgagcacta ccacgtcagc gaaggcggca tcgtcgtact
     7741 gggcaagggc gcccgcgcga tctgaggtcc cgtttcgcgg ctcggcggtc cgggtaaccg
     7801 gggctcatga gcgaccgaaa ccagccgccg cagcagcagg atccgccggg gaccagcgag
     7861 gagatggatc cccggccgcg tgaccggatg acggggtacg tcggccgcgg cctgttcacc
     7921 gggctgcggg cgttgatcac cggcggtgac tccggtatcg ggcgcgcggt ggccgtcgcg
     7981 ttcgccaagg agggtgcgga catcgcgatc gcgtacctga acgagcactc cgacgccgag
     8041 cgcaccgcgg ggctggtgcg cgcggaaggg cggcagtgcg tgctgctgcc aggggacctc
     8101 gcgggcggtg agcactgccg ggacgtggtc gagcagaccg tgcggctcct cggcgggctc
     8161 gaaatcctgg tcaacaacgc ggcgacgcag tggccggtgg attcgccgga ggagctgacc
     8221 gaggaccagt ggatgcacac cttcgacgtc aacatccaca gctacttccg cgtgacggcg
     8281 gcggcactgc cgcatctgcg cgacggcagc gtcatcatca acaccggctc ggtgaacggg
     8341 ttgcgcggca acaagtccct catcgactac tccgcgacca agggcgcgat ccacgcctgg
     8401 acctacgcga tggcacaggc gctcgccgac cggcggatca gggtgaactg cgtggcgccg
     8461 ggtccggtgt ggacaccgct gatcccggcc accttcccgc cggaaaaggt cgagaagttc
     8521 ggcctgcagg tgccgttcgg ggaggcggcg catcccgacg acctggcgcc gtcctacgtc
     8581 ttcctggcgt cgaaccagct ttccggctac tacacgggag aggtgctcgc cgcgctcggc
     8641 ggcgagacga cccctggtgg ttgatcagcc gcggttctcc ctgccgaact cctcgctgag
     8701 ttcactgtgg acggtgtcga ggcagtcgta gtcccgttcg ggcaacgtgc tcagccgtcc
     8761 gagcacgttg tccccggcac cgttcgcggc ggccctgcgc aggatttcgt cgcgccggca
     8821 agggtattcg acatcggtga ggaagtcctg gtagttccgc acgtggtcct ccgtatccgg
     8881 gtggctacgc cacctggggt acccggaacg gcaccgtccc aaccgggcac ggggagacca
     8941 gcaaaatgat ggatccggtg cgcggcaaag cgctgctaac ttgccgtcga cgacagcttt
     9001 acggctcggc gaaagggaaa ccatgtcctt cggctcggtg gtctgacggt gtccgcactg
     9061 gaacggcagg tggccgccgg gctgtcggtc ttgctggggc tcagtgccgc caccggtgtg
     9121 ctcacccggc ggtccggcag gcgcgaccgg aagcggcgct acccggtgca ccggcgtgcg
     9181 gacgggacgc tcgtggagtt cgccgcgcat ctgccggacg acgcccgtta cgtcgtgctg
     9241 ctcgaagccg ggctgggcat gccgcacgag tactgggact gggtgtgcgc cgaactcccc
     9301 ggcgacgccg ggtggttccg gtaccaccgg ccggggtacg gcctcagcac cccgcggccc
     9361 gagttcgccc tccgcgagca cttcgatctc ctcgacgagc tgcggaacgc ccatttcccc
     9421 gaacgccccg tggtgctggt cggccattcg ctcggcggct acctcgcggc ggcatacgcc
     9481 gcgttccacc gcggcaccga ccgcggcatc cggcggctgg tgctggtgga ttcgacgaac
     9541 atccggcagg tgcaccgcac cgcgggaagc gcgcccgacc gctgggcacg ccagacgatg
     9601 gtgctggaac ggatcttcgc gctgaccggg ctgggcgcgc tgagaccggc cgcgaaccgg
     9661 cggcgcacct acgccgacga ggtgaaccga acccatcgcg cgttcctgag cgagtaccgg
     9721 tcgtgggcga ccgcgcaccg cgaataccgg gcgtcgcagg actttcccga gctgggcgac
     9781 gttggcgtgc cgatggacgt ggtgaccgtg tccaacgggc tcgccagctc ggcggcgcac
     9841 cggtcggctc aggcggagct gctcgatctt tccacggagt ccgaacacca cttcgtgcag
     9901 gacgcggaac acgagtccgt cgtcgcgacg cgcgagcacg ccgcggaggt cgtgcgggtg
     9961 atcgcggccg gtatgcggtc cgaggtggag gaggtgcgcg atgcgcggtg agcggtggaa
    10021 gaccgcggcc gtgaccacgg gcctggcgac gtggctggtg gtcaccgcgg cgggccagtt
    10081 gccggacacc cggttcgacg ggctgctcgg caagggcgcg tggcggatcc cggtgcccaa
    10141 ctggcggttc ttcgggccga acccggggac caaggacgtg cacctgctct accgcgacgt
    10201 ctcggcctcg ggggcgacgc cgtgggagca ggtcccggtg accggcgacc ggccctggta
    10261 cgcgctggtg tggaacgcgc gcaatcgcag cccgaaggcg ctgttcgact cgctgcagtc
    10321 catcacaacg ttcgcggcta ccgtccgcgg cgacctcgac cgcatcgaga agtccttcgg
    10381 ctacggattc ctcgccgaat acgtacgcga gcacctcccg cacgacccgg tcgccgaggc
    10441 gacgcagttc ctgctgatgg agtcgttccc gtcccgcggc gacgatctgg aaataattcc
    10501 cgttttcgct tcgcgagaga tcggtctcga cgacgtcaaa cgggagcttt gtgaatgaaa
    10561 atattgatgg atacatcggt ccgttaagga gagaagatgc acaacgatgt cgtggcgacc
    10621 tatgccaacg agaacctgcc ttcagtgtcg cccgggttcg tttctaccgg cgatgacgag
    10681 atctcgtatt tttgtacctc tcaagcctac ctgaccaatt tctatgacag ctttttcaac
    10741 gacatccccg ctactttcgc cgtaaactcc tgacattcga aaccggtcac gcggtcgctc
    10801 ccgtggtcgc gcgagcgggg tgagcgccgc ggcgtcgggt tcgtcggccg tcgccgcggc
    10861 ttctccgttc cagtaaagga aacccatggc catcggacgt cagcacgatg tcgtcgccag
    10921 gcgggtggcg tcgctgggca ccctcgtttc ggcgttggag atgctcagtc agtccgctcg
    10981 gttcgaaaag ggcgagctgc tcagcacaca gctcggtaag accaagccga agttcgcgaa
    11041 gcggtttccc cgtctcgtcg acgcgctctc gtcgaagaag gcgagcgtcg ggttgtacgc
    11101 ggcgcaggcg gcggcttcgg cggccacgat cgcttggccg cgctcgcgtc gcgtccagtt
    11161 cgcgggcgcg gcggcgctcg cggcgatcgg ggccacgaat cgcgcgcgca acccgttcgg
    11221 cggcgacggc gccgatcagt tgcagcaggt catcaacgtc acgttcgccg ccacggccac
    11281 gctcaaggac cgcgagaagg cgcgcgatct cgccctgcgc acgctggcgc tggagaccac
    11341 aatctcctat gtcgcgtcgg gtctggtcaa agtggtgtcc ccggtctggc tccacgggga
    11401 ggccttcgag ggcatcatcc gcacccgcaa ctacggcgac ccgcgcgtgc accgcctcgt
    11461 cacgcggttt cccctgctgg gcaagctcgt ttcgtggagc acgatcgccg ccgaactcgg
    11521 cttcccggtc gtgttcgtgc tgccgctgcc cgcggcgcgc gcgtacctcg gcatgatgac
    11581 ctcgttccac ctcggcatcg gccagttcat ggggctgaac cggttcgtgc tcgccttcgg
    11641 cgcgacgcac ccggccatcc tgcacgtgct ctccgagcgc aaatcacgct cgacgccacg
    11701 ggaacggggc gtggggaaag aagaacgaac gtccgagcaa agggagaact gatgcgcaac
    11761 gacacgatca ccgatttcgc caacgaccac ctgggcgtgg tgacgccagg actggtcggc
    11821 agcggagaag acgctccgcc ggtgttctac gtgacgtcgg ccagcgcctc gctcatggtg
    11881 cccacggtca ccgacgcgac ggtgcagacg atcgtgatct cggccgcggg ctgagcatca
    11941 ccttgacgcc ctgatggcca ccatcacgcg cccacccgtc gcccgaccgc cgccccttga
    12001 ggaagcgctt cgcgctgcgg tgttgtgccg cgatggtggc catcagggac ttttccctcc
    12061 ccctcgggtc agacggtgag ggcccagctg gtgagcgtgc cggtgtcgcc cgcgaacgcg
    12121 tcgtagacga cgagcgtcca ggtaccggcc gcgttctcgg tcgtcaccgg aaccgagaag
    12181 tccctcgtgc cgaattgcgt gcacggcgcg ttcccggtcg gcttgaccga gtagctgcgc
    12241 cccgacggcc cggtcaggct gatccggagg tcctccgcgc aggtgtgcga ggcggtgatc
    12301 ttcacctgca ccggcgagtt cgcggcaccg gcggtggtgg cggacacggg gctgttcacg
    12361 gtgccgtagt cggtgatcgg gtaggccgtg ctgttggtga agacccggtc gcccggcggt
    12421 gtcgacgatc cgaccgcgag cttccagacc gcgtaggcga tcgcgtcgct gttgcggtcc
    12481 atcgggacgt ccttcaggtt cgacagcgtg tcgcaggaac ggtggtagca gttgtcgaac
    12541 gccgcacccg cggtgccgcc ccactttcgt tgctgcgccg cggacttgat gtcaccggca
    12601 cccgtggcga ggccgccgac ggggatcccg gcgctcttga aggaggcgtg gtccgaacgc
    12661 ccatcgccct cgctgtcccc ttcggtcggc acgttgagcg tggcgaagta ctcgtcgaac
    12721 accgccttga tcgaggccac gtcgtcgtag acgaaatgac cccagttgct cgacgcgatc
    12781 atgtcgaagt tcaggtacgc cttgatcttc gaccgctccg acgacggcag gttgttgacg
    12841 tagaaccggg agccgcgcag ccccgactcc tcgtcggccc accagccgaa ccggacgcgc
    12901 ttcgccatct cggggttcgt cttcgccagc gtcagcgcga cctcgaggat cgccgcgctg
    12961 ccggaaccgt tgtcgttgat gccggggccc gcggagacgc tgtccaggtg cgcgccgagc
    13021 atgatcacct ggttcgcgtc gcccttcggc cattccgcga tcaggttctg gctctgcccg
    13081 gagcagctcg tgcacgtctg gcggctggtg gtgaacccgg cctccttcag cttctgctcc
    13141 acataggaca ccgaagcggc gtaaccgcca ctcgccgcgg tgcggctgcc gccgtactgg
    13201 cgcgcgatgg tctccagctg gctcaggtgc cccctgacgt tggcgagtga gatgtccggc
    13261 gcggcgaccg cgtgcggcgc gggggccacc ggtgccgcgg gtgccgcgac cgcctgcccc
    13321 atgcccagcc ccagcgccag tgccatcccg gcggcgaagc ccttgaaagc tcgcacgatc
    13381 agtgctcctt agttcggggt tggagcggtg cggcggcgcc gatcggggtc agcgccgccg
    13441 caccgtggtc agtgggtgat cagcaggcgc cggagtcctt ccagacgtac caggaaccgg
    13501 gcgaaccggg ctcggaaccg gccgagtacc agttggacgt ccacttgtga ccgttgtgcg
    13561 aaacgacgtc acccggcacg tacagcgtgt tggcgtccca tgccgcgacg ccgtcgcagc
    13621 ccgtcggcgg gttgccgctg ccgaccgtca ggtcgtactg cacggtgtgg tccacttcga
    13681 caccgtccgc gttgatcgtg accttgctgg tcccgttcgg ggtggtggcc gcggtggtga
    13741 tcgtcagctt cgacgagcca cccgaggtga tcgactccgg ctcgaacttc gcggtcgcgc
    13801 cggtgggcag cccggaggcg gtcagcttga tcgactgcgc ggtgccgttg gtcgtcgtgg
    13861 tgcccacggt gaccgtcgcg gactcgcccg gcttcacggt gcccgaagtt gggctcaggc
    13921 tgaccgagta gtcgttcttg cccggctgct ggttgcaggt ggtcggctca ccgctgaccg
    13981 ggggcacgct gacggcgttc cacgcggcct tcaccgcgtt gaactcggtg cagctgttgg
    14041 ggaacagcgt gagcgacgct tccagggtgg ccttgcgcgc cgagctggtc cgccacgatg
    14101 aggtcttctt cagcagggcg ttgtagaaga tcttgcccgc cgactggata ccgatcccgg
    14161 tgatcgagct gttgttgcag gtcgggctgg tcggctggcc gtcggtcggc gcggtgccct
    14221 cggcgagcag gtagaaccag tggttctgcg ggcccgcggc ggcgtgcacc tcggtgttcg
    14281 ggatcgacga cgagtagcag ttcgggtcgc cgaccttcga cgggtcgtac atgtaccgga
    14341 tcgggccctt gccgaccagg ttcacgcctt cgccgacctc gtagtcgggg gtgtccttcg
    14401 cgttgttcgt gtagaactcg gtgagcgcgc cgaagatgtc accggtcgac tcgttcaggc
    14461 cgccgttctc gttgcccgag cccgcgccac ccggggtgtt ctggaagacg ccgtggccga
    14521 actcgtggcc gacgacgtcc atcgaggtcg cctggcgccg gttgtcctgc gagtgcccga
    14581 agtgcgtcga cgagccgtcc cagtacgcgt tgacgtcgtt caggccgacc gatgccggga
    14641 acccgcgccc gttgccgtcg atcccgttgc gtcccagcca gtccttgagc atgttccact
    14701 cgtgctggac cgcgaacagc gtgtcgacgc agccggtctc gaggtcggtg ccggagccgt
    14761 tgccccatgc gtcgtcgttg ccggtgaaca cggagccgcc ttcacgcccg cagctgatgc
    14821 cgctgcgccc ggggtcccgc atggagtacg agctgccgga gcccgtggtg tcgatcgtga
    14881 cgttgcctac gtagtagctg ttgccgctgc ccaagggcgc cggcggcgtg ctcgcgggcg
    14941 tgcccgtggc gcgcggcgcc agggtcttga cgtcgtcgcg cttgtccagc acggcgcccg
    15001 tcgcgccgtc gacgaagacg tgcaggttac tcggcaggtt cgcgcccctg cccttgacga
    15061 cgacctcgta ggcgagcttc ggggtggccc cgcccaccac cacgaggttc ggcgaggaca
    15121 cgctgtccac tgtggacagc tggccgcgtg cgatggaggc ggcgcggtcc gcgctgattc
    15181 ccggcttcgt gcccaccttg atgtcggcgg tggccgcggc gctggtgtcc cggacgtgac
    15241 cgacaccgtc ggcgaccacg accgcgtcgc caccgatgac cggcaggccg tggtaggtgc
    15301 gctcgtagga cacgtagaac aggcccgcgc caccaggggt gacgccgagg cggtggaacg
    15361 cctcgttcgc gcccttgctc agcttgtcga cgccgatggc cgcggcctgg tcggccgcgc
    15421 tgatggcggc ggcctcgggg ctggctggct gtgcgggagg tgcggccggt gcggcggtgg
    15481 ccgggatcgc cggcatcgcc atggtcatgg ccaggccggc tatcgcagcc aggcctgatc
    15541 tcagtccacg ctgagtcatc gcggatacct ttcgttcaag gcaggccgcg ctgcccggcg
    15601 agacggggaa acgggccgtc gcgccgggca gcacggtgtg cgggggagaa ccgtccgagg
    15661 aggtgcaggg gacgagacct cggacgagct tgagtaaaga attcggcaag agggccgtca
    15721 atgcgctgag tggactagtg gtggcctgcg gatttatccg tagtgccccc gcaaacactt
    15781 gcacagcagc ggttttccac cccggagctg ctggaagcga ctttcgtatg gtcttctgct
    15841 aatacgtgca tcgatgctgc ggcggcgtca tcctggttac gaattttcct tgatcgccaa
    15901 ggttcgtgac gcatcttggc cggtcagcga ggcgctgggc gctggctcgc gaaggcgacc
    15961 gggggcctcg attcgcgagg gcgtgattcg gcgggccctc ggccgcctgg ggcggagggc
    16021 gcgagaggtg gtcgcgtggt ggtgggccgc cgtctggcgg cgctggtcgt cagacagcgc
    16081 agcaagctcc ccgccaactc gctcaccgca atgatcgtgc gcctgattac ctgcccggcc
    16141 aggatgggat cgcactgagc cgctgcatcg agagtttgcg ccgagccgtt cgccggatgg
    16201 gggccgagaa tggttcggcg cccacggttc gaataccggg ctcgttcgtt ctgcccttca
    16261 cccgggagtg gctgaagaac gggggtttcg tcgatcagtc cgctgtggac acagcgactg
    16321 ccgggccgcc gatggcggcg gagttgctta ggcggcgcgg ggttgggcgg tgtggctgtt
    16381 ggttcgggat cttcgccagg ggtcgatgaa gtcgggtggg gtgaattcgg ggagtccgtt
    16441 gaccatgcgg agtgtccagt cgctacgatg caacagccga tggtggtgtc cgcatagcag
    16501 cacgagattg cccacctcgg tgaggccgcc gtgtgcccac ggtacgacgt ggtgcgcctc
    16561 gcaatgacgc ggcgcgcgcg aacatccggg gaacgcgcat cctttgtcgc gcatggcaag
    16621 catgtatcgg atcgcttcgg tgaccagacg tttcgcccgc ccgacttcga ggggttggcc
    16681 tttgccgtcg agcatcatcg ggatgatcct gcagtcgcag gccaggatgc gggcttcgct
    16741 ggcggtgatg tcggtgacca tgtccaggca ggctttgccc agctcggctt tgaggtcggc
    16801 cagggggatc gtcacgatca gatccgcccg gccgccactg cggttcggcg attcggggtg
    16861 actggcggcg agggcgacca tctccatgaa cgcgtccccg taccgctcgg cctgcccgcg
    16921 ccgcagcgga ttgccggacg ggtcgttcgg ttgggactgg gcgagcgggt cgagcagggc
    16981 gagggttttg gcggcggaga tggggtcgag gtagccgtcg aacttggctg aaccgtcctt
    17041 gcgctggtgg aagtgcagcg cccgggtggg ttcgggagtg tcgcggggtt cggggccgtc
    17101 ggggtcgagg taaccgagga gttccttgcc cagcttggag atttgcgagg tgcccgcctt
    17161 ccgcgccagt tccacaagag accgctccgc gaactcccga tcctcaaccg gagtcgtggc
    17221 ggggattttc tccagcaccc gcacgatctt gtccacgtgc tcgggcgaga tcgcaccctc
    17281 tcgggcagcg tcgccgacaa ggggcgcggc cgcgggaatt tccgtaccat cgatcccctg
    17341 accggggttg gtcaccagtg cccgcttcac cagcctcttc acctcaggtc cggtgcaccg
    17401 cgcgatgtcg gccaccagcc cggccacact cgtgtacccc agatcgcggg caccgccatt
    17461 gtccaggtgc gcgatcatgc ggtggatacg ggcttcctgc tgccaccacg acacgaactc
    17521 ctcccgcaac agcgaggcaa cctcgcgcgc gtcaagtcgc cacagctcat cctgctgcgg
    17581 cgcaagggaa ggagaagtct cgaacaccct gccagtctac cgccgatcgt tcgcatgttc
    17641 gatgatccat ccaggtgaac catgcggcgc aaccgcgaaa cacgttggca tacaagggtt
    17701 tccggcaaca gcgttgcgaa gggtgaagct gggaaaggaa accgaacgaa gcaacgggag
    17761 tcagactcga aaagccatcc acctccttca gtccaaagcc ttctttgaac cgccactagc
    17821 gtcggcgacg ccaccagccg tgtcgacaag cacggcgccc gccgcgacgg ctaaactcgg
    17881 ccggtgactt cccggacagc accgcggatc ctcctcgtcg aggacgccga agcgattcgc
    17941 gtttcggtgg aggccgcgtt gggcacggcc ggattcgagg tgcgtgctcg cgccgacggc
    18001 gaagcgatcg agcaggacct cgtggggttc cggcccgatc tggtggtgct cgacgtgttg
    18061 ttgccgggca gggacgggtt cgagctgctg tcgctgatcc gccgccattc cgcggcgggc
    18121 gtggtgatgc tgaccgcgcg ggacggggtg gaggatcggc tgcgcgggct cggtgaaggc
    18181 gccgacgact acgtggtcaa gccgttcgtg ctggccgaac tcgtggcgag ggtgaccgcg
    18241 gtgctgcgcc ggaccggccg caccaagccg accgtggaga tcggcgatct cgtggtggac
    18301 gccgaggccg ggatggcgct ctaccgcggc gagcggatcg acctcaccgc gaccgagtgg
    18361 aagctgctga gccacctcgc cgcgcaccgc gatcgcgtgc tcagcaagac gcagatactc
    18421 gccgcggtct gggggtacga cgactacgcc gagaacctcg tcgaggtcaa cgtcagcacg
    18481 ctgcgccgga agctcgagca gcacgggccg cggatcctgc acacggtgcg cgggcagggg
    18541 tatgtgctgc ggggcgacgt cggatgaccg ggctgcgcac cacctccctc taccgcaggg
    18601 tcaccacgac cgcgctggtg gtgctcgcgg tggtgctggt ggtgctcggg ttcgtggtca
    18661 gcgcggtgtt ccgcgcgcag gcggaacgcg acgtcaacgg cctgctcgcc gggcgcgtgc
    18721 agctcgcgca gcagctcgcc aagcagggcg cgccgccgca gaacctggtg cggcgcgtgg
    18781 aaacgcgtgg cgtcgaaggc aggttgacgc tgaccgacgg caccgtcttc ggggcgccgc
    18841 cccggccggc ggaggccagg ctgcgccagg tgaaggcgac cttgagcggg cggggacagg
    18901 tcaacggcgc cgcgctcacg ctcaccgccg acgagtcgat cgtcgccggt gcggaatcga
    18961 cgctgcggtg ggtgctgctg ttcaccgggc tggccgcggt cgcggtgacc gcggccgcgc
    19021 tgctcgtcgg tgtccggatc gcactgtccc ctttggacgc gatgaccggg ttggcgcggt
    19081 cgatcgtgac cgggcggcgc ggcggcaggc tggccccgtc gagcgcgaag accgagctgg
    19141 gcagggcggc gagcgcgttc gacgacgcac tggacgcgct ggagggcgcg gaacgggcgg
    19201 cacgcgcgtc ggaggagcgg acgcgccggt tcgtcgcgga cgccgcgcac gaactgcgca
    19261 cgccgatcgc gggcgtgcag gcggccgccg aagccgtgct ccagcaggga ccggacgcgg
    19321 atccggcgct caccgaacgc ctgcacctgt tgctggcgcg ggagtcccag cgggcgggca
    19381 agctggtgag cgatctcctc gacctcgccc acctcgacgc cggggtgcgg ctggacgccg
    19441 cgcccgtcgc gctgctgccg ctcgcgcagg cgcaggcgga tcgggcgcgc ctgctcgcac
    19501 ccgaactcac cgtcgaggtc tcgggaccgg acgcggtcgt cctcggcgat tccgaccggc
    19561 tcacccagat cctggccaac ctggtggaca acgccgtgcg cgcgatggcg gggcacggca
    19621 cgctgaccct caccgtgacc gagtccggtg tggtcgtgtc cgacaccggg ccgggcgtgc
    19681 cagccgagga cgtcgagcgg atcttcgacc gcctggtgcg cctcgacgac gcccgcggcc
    19741 agagcggatc cgggctcggc ctcgcgatcg cacgcgggtt cgcccgcgca cacggcggcg
    19801 acctccgcta cgagccctcc gccggagctt cgttcgttct ttacggactg tccaagccgg
    19861 actctcaagc cgggagcagc agcccgtcga gtcgtcctga gtgaccgggc agcacgcggt
    19921 cggccggggt gccgagcaca ccctccagca tggccgcgta cacgtcgcgg aagtccacgg
    19981 tctgcttgag atcgccgtcg gcgaggtcgg tcaggctcgg ctcctcgccg tggaacccgc
    20041 cccgcacccc gttgcccagc acgaacatcg ggcccgccgt gccgtggtcg gtgccctggc
    20101 tggcgttggc gcgcacccgc ctgccgaact ccgagtacac cagcaccacg gcctgcttgc
    20161 cgcggtcggt cccggccagc cggcgcgcga acggggtcag cgcaccgtcc aattcggtca
    20221 gcaaccgctg ctgcgtgcca cgctcgtcgg cgtgcgtgtc gaaaccgccg agcgacaccg
    20281 aatacgcgcg ggtcggtaca cccgcttcga tcaggctcgc gaccacgtcg agctgcgcgg
    20341 ccagctttcc cttacgctgc ttcttttcct tgtcgtgcgc cgcgccgccg agcacgcgca
    20401 ccgcgttgtg cagatccccg acggacttgg ccgccttcgc ctgccagaat ccttcgtccg
    20461 gctgagcggc ccccagcccc tcgaaggact tcccgagcgc gcccttcggc aacgccaagc
    20521 cgccgaccgg taacgacgcg gccgcggtac ccgcaccg
//
