LOCUS       NZ_CP059997            85973 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6141580
            Orig. end                         :: 6227553
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..85973
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /candidate_cluster_numbers="5"
                     /candidate_cluster_numbers="6"
                     /contig_edge="False"
                     /product="cyanobactin"
                     /product="PKS-like"
                     /product="NRPS"
                     /product="T1PKS"
                     /product="lanthipeptide-class-v"
                     /product="linaridin"
                     /region_number="27"
                     /rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /rules="(t2pks2 or ksIII)"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(APH and HopA1)"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..24262
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /kind="single"
                     /product="cyanobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24262
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14262](+)"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14262
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
     gene            complement(119..934)
                     /locus_tag="HUW46_RS29525"
                     /old_locus_tag="HUW46_05857"
     CDS             complement(119..934)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225614.1"
                     /locus_tag="HUW46_RS29525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05857"
                     /product="glycoside hydrolase family protein"
                     /protein_id="WP_215542049.1"
                     /transl_table=11
                     /translation="MHPIRRFAVLALAALLLVPSVASASTAEAAKKGVSAANVDGVTDA
                     LADVGASWFYTWDSGPKGIAAPPGAEFVPMIWGPGSVNPDQLAQAKASGSTLLAFNEPD
                     MAGQANMSVEQALDLWPQLEATGMRLSAPAVAFGGDQAGGWLDRFMSGAAERGYRVDFI
                     PLHWYGGDFSGAATGQLKGYLQAVADRYHKPVWLTEYALTDFSGPAPRYPSEAEQTAFA
                     KDSAAMLGDLSSVERYAWFTLSTATAPTGLYSGKDANATGVAYRDATPH"
     gene            complement(977..1732)
                     /locus_tag="HUW46_RS29530"
                     /old_locus_tag="HUW46_05858"
     CDS             complement(977..1732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639002.1"
                     /locus_tag="HUW46_RS29530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05858"
                     /product="thaumatin family protein"
                     /protein_id="WP_215542050.1"
                     /transl_table=11
                     /translation="MRTRSWRLFAVLALAAAVGIPSPSQAAPAANHTVTFVNHSGDTVW
                     IGSAVNADGSANLANLPTLKDGESATITVPESDGPGHWRGKFFARQGCTGESGRDFHCA
                     VGDCGPDADHCSTGEEPASLAEFNFDPADKLAPWYNVSYVNAFSLPVTIDPDNATPPPG
                     APASCGQAGCSETVLPSCPAEDLRKWPDSSPMNCVNPNRDAKTSYSDLVQAKCPRAYAW
                     SKQDTEPGNQTMFQCTSCSGFTVTFHSGR"
     misc_feature    1759..1774
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
     gene            1925..2746
                     /locus_tag="HUW46_RS29535"
                     /old_locus_tag="HUW46_05859"
     CDS             1925..2746
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05859"
                     /product="hypothetical protein"
                     /protein_id="WP_254125006.1"
                     /transl_table=11
                     /translation="MFRKTWLVFVGVAVVLGGVVPAAAAAPEVPSGKTQCDGDGTSGNR
                     VEALYVRGDGQPDRYAELADRFRTFADQIDDDFAEAGKRLGGGSRHVRYVTDADCRATI
                     ANVAIPQSSMDTVDTITDAIKAKGFDRADRKYLVWYDKDGCGLAFGNGGDDRPGADNPY
                     NAGPHYATVGTGCWSWQASGHELLHTLGAVQGSAPHATKNGHCWDDEDIMCYDDGGIPN
                     PPGGLVKVCEGAPENQIDCDGDDYFNTNPPEGSYLKTHWNVANSSYLITKG"
     gene            complement(2747..3550)
                     /gene="nshR"
                     /locus_tag="HUW46_RS29540"
                     /old_locus_tag="HUW46_05860"
     CDS             complement(2747..3550)
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nshR"
                     /inference="COORDINATES: protein motif:HMM:NF000477.1"
                     /locus_tag="HUW46_RS29540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05860"
                     /product="NshR/TsnR family 23S rRNA methyltransferase"
                     /protein_id="WP_215542051.1"
                     /transl_table=11
                     /translation="MTSPDLITERSDPAVQRIIDVTKHSRSVVKTALIEDVEPLLQAIR
                     AGLEFTEVYGLETTSLPEELLAACAERGIGVRLLATTIANQVFKTEKKPKAFGIAKVPR
                     PRKLADLNGTTGDLILLDGVKIVGNIGAIVRTSFALGAAGIVLVDSDLTTIADRRLIRA
                     SRGYVFSLPIVLASREEALAHIRESGARLVLFDTGGALTVADLGTAEERLVLAFGSEKT
                     GASGEFAGISADAVSIPMNPLAESLNVSVSAGIALHARAHRNLPR"
     gene            complement(3645..4760)
                     /locus_tag="HUW46_RS29545"
                     /old_locus_tag="HUW46_05861"
     CDS             complement(3645..4760)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102230.1"
                     /locus_tag="HUW46_RS29545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05861"
                     /product="cytochrome P450"
                     /protein_id="WP_254126654.1"
                     /sec_met_domain="p450 (E-value: 6.4e-15, bitscore: 53.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAWSVTNPDLLKRLLSDPRVSKDPNQHWPAYTRGEIPADWPLHL
                     WVSVKNMFTAYGGDHRRLRALVSKAFTPRRTQNLRPQVEQITAELISALAAGPNTADLR
                     ETFAYPLPIEVICQLFGIPDDARPGLKRAVDGVFNTTATPEEAAANVQDMYRILSELVA
                     AKREKPGDDLASALISARDEDNSRLEEAEMVDTLILVISAGHETTVNLLDHAITALLTH
                     PEQLRLVLDGERTWTDVIDETLRWQAPVAHLPLRYAVEDIEIDGLTIQAGEPILASYAA
                     AGRDSAHHGEDADRFDLTREDKGSLAFGHGVHYCLGAPLARLEAEIALPALFTAFPDLT
                     LAVPAEELETVASFISNGHRTLPAFLTKPAD"
     gene            complement(4742..6172)
                     /locus_tag="HUW46_RS48455"
                     /old_locus_tag="HUW46_05862"
     CDS             complement(4742..6172)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153239.1"
                     /locus_tag="HUW46_RS48455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05862"
                     /product="cytochrome P450"
                     /protein_id="WP_254125008.1"
                     /transl_table=11
                     /translation="MTSASEAPATPDGPVPPPGCPAHAPTRLHGPEFAADPAGTYARMR
                     AEHGSVAPVELAPGTHAHLVIGYEAALEVLREPSTFPRDPRRWERRMPPDNPVLPMMGY
                     RPNCLFTDGAVHARLRGAVTSSLGRVDPHRLRGYVEQTARGHIGRFSQRGSADLLREYA
                     TSTALGVFGHLFGCPPELGDRLLESMRGIFDMDDPEQANANLGQCMGELIALKRRQPGP
                     DLPSWMMAHPARLTDEELLHQMILMMGAGTEPQQNLIANGLRLLLSDERFAGDLAGGSM
                     PVEDALDEILWTDPPMANYSASYPWTDLDLFGVRVPADQPLVISFAAANTDPALNIEHR
                     AGNRAHLAWGAGMHTCPAQLPARIIASAAIETLLDALPDVRLAVPVEDLVWRQGPFHRA
                     LSALPVQFTPVTVAAPPDPLPPSAPPTQQSGERAWTAPPAQSSSTPLDVTSTEKAPGSA
                     NGGKRPWWSSLARWWRGR"
     gene            complement(6169..6765)
                     /locus_tag="HUW46_RS29550"
                     /old_locus_tag="HUW46_05863"
     CDS             complement(6169..6765)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153241.1"
                     /locus_tag="HUW46_RS29550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05863"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_215542053.1"
                     /transl_table=11
                     /translation="MASVLSPDADYVPASVRTSVKILVAGPFAVGKTTFVGTLSEIRPL
                     RTEETMTQAGAFVDDLAGVPDKQTTTVAMDFGRLTLNPELVLYLFGAPGQQRFTQMWKD
                     LAHGALGALVLADPRRLEQSFEVMDLLEELGMPYAVAINQFDGSPRFPEAELREALDLL
                     PQTRLVVCDARDRASSANALIALVDHLFTTRQEHL"
     gene            complement(6743..7096)
                     /locus_tag="HUW46_RS29555"
                     /old_locus_tag="HUW46_05864"
     CDS             complement(6743..7096)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634220.1"
                     /locus_tag="HUW46_RS29555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05864"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_215542054.1"
                     /transl_table=11
                     /translation="MTEPRRERALVRPHVVTGGRAHPTRNTFDLATVVVATKTPVAGLS
                     PEKRRMTELCRGGALAVAEIAAHLGLPASVTKVLLSDLVDTGHIVAHATVGSADHADLQ
                     LLQKVLDGLRALT"
     gene            complement(7093..7512)
                     /locus_tag="HUW46_RS29560"
                     /old_locus_tag="HUW46_05865"
     CDS             complement(7093..7512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153253.1"
                     /locus_tag="HUW46_RS29560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05865"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_254125010.1"
                     /transl_table=11
                     /translation="MTDPSNKLGWMLDDALQMPETLYAVLLSADGLLIAHSQRISRDDA
                     ERIAAGMSGLQSLARTTAEFCGETAEQWRQTLTEFTGGYVFLVAAGPGAYLAVSATNRV
                     DMEGVSTRLQQLVQRLGQELTAPARFAPQGYGSPA"
     gene            complement(7509..8804)
                     /locus_tag="HUW46_RS29565"
                     /old_locus_tag="HUW46_05866"
     CDS             complement(7509..8804)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020667344.1"
                     /locus_tag="HUW46_RS29565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05866"
                     /product="ATP-binding protein"
                     /protein_id="WP_215542055.1"
                     /transl_table=11
                     /translation="MDQPLLIVAVSVLLAVVVLLVVLLVRQRGITTRARAMSDALHHEL
                     RARQAEQEHLTRTRLPSLIESIADPAVSVPGPLTQGNGDPHGVVLAMVADYVRQARSGA
                     AQAAASTLKAMMRSVQNLANEQQVAISEAEQRHDDPAVLADLLKIDHANSQLARRAQAT
                     AVLCGSWPGQQRSASTLTDVARGATSRIRDFPRVAIPATSETAVVSRAVEPVVLAVAEL
                     LDNGARHSQPGSKVEVNFQQAHNGLAIVIDDAGVGMTVEAVQRATWLLAQRGTQDIAGL
                     GDPPRIGFAVIGILAARYGFSVSVDTRSPYGGVRAVVFLPSELLTRENAPSVHTMPVSR
                     VLEPENRDPVPEQAPAEAEAPAPSPAEDLGRTENGLPRRRRRAPAVEPAPQPALPEPVA
                     ARTPATLAAWQRGTRAGRETAPAPADSERDSQ"
     misc_feature    9425..9440
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.51"
                     /tool="antismash"
     misc_feature    9734..9747
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.32"
                     /tool="antismash"
     gene            9762..9920
                     /locus_tag="HUW46_RS29570"
                     /old_locus_tag="HUW46_05867"
     CDS             9762..9920
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05867"
                     /product="hypothetical protein"
                     /protein_id="WP_215542056.1"
                     /transl_table=11
                     /translation="MTENLMESVAPQLSPPVTRQPVGTAAETADGAELSILTIGPVTIS
                     FAADDDE"
     gene            10001..11944
                     /locus_tag="HUW46_RS29575"
                     /old_locus_tag="HUW46_05868"
     CDS             10001..11944
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyanobactin: cyanobactin_synth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03895.1"
                     /locus_tag="HUW46_RS29575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05868"
                     /product="PatA/PatG family cyanobactin maturation protease"
                     /protein_id="WP_215542057.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 7.7e-30, bitscore:
                     103.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="cyanobactin_synth (E-value: 1.8e-173,
                     bitscore: 576.6, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVCEVPGIPGLAELWRRTLGDEDVCVAVVDGPVDLGHPAFDGA
                     ALTRLAGIWPEEGLDSDKAVHGTHVASVLFGQHGGPVTGVAPRCRGLSVPAFSQRKGRT
                     SQLELARGVELAVEAGAHVVNISGGQLSPSGEADRTLADAVRYCTERGVLVVAAAGNDG
                     CFCAHVPAALPGVLAVGALDDRGVPMAMSNWGAEYRSHGIVAPGEHILGARPGGRTDRA
                     TGTSLAAPIVAGVAALLLSLQHRAGLRPDPLAVGTALLDSADPCDPSGSAACERFLTGK
                     LNIERAVETVTSSMSVTPPEPAAADVAGGEPRQEPAAPELLVPSASPEPIVIPEPAKES
                     CGCGCDGTAPDSCRKPAVVMSAEPDRSPAEHPVYAIGVLGYDFGTEARRDSFKQLMAPV
                     AADGTVVPANPYDARQMVDHLLAHPSEARALIWTLNLELTPIYAIEPVGPYAAEVYELL
                     ARLLSGQVAAPTSDDFLERVAVPGRYSGRTVRLFSGQSVPVIELEQRRGLYGWEVNRLT
                     ESAVDAAEAVPGESDDEATKQALRQFLTRVYYDLRNLGSTSRDRALNFAATNAFQAAHT
                     FATALAEKMALDTITVEKSPFCRQDSDCWDVKLRFFDPENSRRAKRAFRFTIDVSDLLP
                     VTLGDVREWAET"
     gene            11929..12159
                     /locus_tag="HUW46_RS29580"
                     /old_locus_tag="HUW46_05869"
     CDS             11929..12159
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04220.1"
                     /locus_tag="HUW46_RS29580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05869"
                     /product="cyanobactin biosynthesis system PatB/AcyB/McaB
                     family protein"
                     /protein_id="WP_215542058.1"
                     /transl_table=11
                     /translation="MGRDVTARPGIAPPQVAPVRRPELVEPHRCVDVVHGTPDELIAMR
                     LRLMHGANFNDPQRWLDPTYQRMRSSFPRNT"
     gene            12267..12569
                     /locus_tag="HUW46_RS29585"
                     /old_locus_tag="HUW46_05870"
     CDS             12267..12569
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05870"
                     /product="hypothetical protein"
                     /protein_id="WP_215542059.1"
                     /transl_table=11
                     /translation="MPNPKTPRRRPPAARRRVEAPSEPAVSTEPEQPAGEQVSIEEVEA
                     AVALADRLDRPVRIPPERRLDTGLADYAMWFRMFSAAPSAPPPSGGDTRAGRIWA"
     gene            12574..14262
                     /locus_tag="HUW46_RS29590"
                     /old_locus_tag="HUW46_05871"
     CDS             12574..14262
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyanobactin: cyanobactin_synth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="HUW46_RS29590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05871"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_215542060.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-19, bitscore:
                     69.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="cyanobactin_synth (E-value: 2.4e-97,
                     bitscore: 325.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEIAAIPGVGELWAQTLGDPAVTIGLVEGPPELSHPCFDGADLT
                     VLEPHWLPRVPVVDGLPEHATFVASVLFGQPGGPVRGMAPRCRGLLVPALRDEPTLLDP
                     VNAVRAIETLVEAGADIVHFAASHPTGSGDADPLLAGAVRRAYEAGVLVVAPAGNDYGG
                     NYVAPAVLPEALAVGALDDDGVMFRFSNWGERYSGHGIAAPGGDLTAAAPGGGTSVHKG
                     TSVAAPIVTGVAALLASLRQRRGLPPDPLAVRDALLASARSCGGADSHGEPARCLAGKL
                     DVPAATRLALAGARPEVVLSARRRNPVYAIGTLGYDFKTEARRDSFQQLMAPANPYDAR
                     KMTEHLAAHPTEAKALTWTLHQELTPIYAIEPTGPHAAEGYAVLARLLRGQLEAPSSDG
                     FVERVVLPGAHDGRTARLFSGQSVPVLELDRLSGVHGWEVNRLAAAVLPGGSRVALRQF
                     LDRVHHDLRNAGATSADRALNFAAANAFQAARIFDAALAAGLAFDGVTVTPSPFGRPGG
                     DCWDVKLRFFDPENDRRARRAFRFTVDVSDTLPVALGEVREWAEP"
     cand_cluster    12834..85973
                     /SMILES="NNC(CS)C(=O)CC(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(APH and HopA1)"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="NRPS"
                     /product="T1PKS"
                     /product="lanthipeptide-class-v"
                     /product="linaridin"
                     /protoclusters="2"
                     /protoclusters="3"
                     /protoclusters="4"
                     /protoclusters="5"
                     /protoclusters="6"
                     /tool="antismash"
     cand_cluster    12834..53865
                     /SMILES="NNC(CS)C(=O)CC(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /kind="single"
                     /product="PKS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    12834..53865
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[32833:33865](-)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(32834..33865)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
     gene            14285..15124
                     /locus_tag="HUW46_RS29595"
                     /old_locus_tag="HUW46_05872"
     CDS             14285..15124
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012799.4"
                     /locus_tag="HUW46_RS29595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05872"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_215542061.1"
                     /sec_met_domain="TP_methylase (E-value: 1.6e-11, bitscore:
                     43.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETPSHPGVVEVPWNLTVPEADIHLVGYGMRMPNDLTLEALAVL
                     KRCKRIFGIPPLHAPEFGIPEMENLYLHYGPEKNRRQTYREWLDLVLDAAATDAPVALA
                     TGGSSMVGALVPHRILEEAPRRGLTVHVTNAVSCFDGIWADLNIEPFFGFSVWEATAFV
                     KLGIAPDTSAALMLPQAPIFDVSTGPDVGTNTMTTSSAVSALRDHLLRYYPGGHQVRFV
                     HTGSGTGARAMTAAIETLPLAELDHPGRNLLSTLVVPRLEPSAQLDFARREEAAAKS"
     gene            complement(15167..16408)
                     /locus_tag="HUW46_RS29600"
                     /old_locus_tag="HUW46_05873"
     CDS             complement(15167..16408)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01426.2"
                     /locus_tag="HUW46_RS29600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05873"
                     /product="macrolide family glycosyltransferase"
                     /protein_id="WP_254125012.1"
                     /sec_met_domain="MGT (E-value: 1.8e-40, bitscore: 138.5,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAKRIVVAGMPAAGHFNPSLPIVRELARRGFEVTYYTSDDFRA
                     RVEEAGCEFRTYPAGTLGPADIAEATRNGGPVRVVARVLTATEALLPLLLSDLDTRRPD
                     AIAFDSNAIWGRMAAARLGLPMISLMTTMLIGGKAMARLNAREWLHFLGEAIPGVPAAR
                     SAKRRVVRQFGKDAYPPAPGLPMRGDVTVFPVPRWMQSPDPRIDDGCHFVGPTIRPPRE
                     DAPLDDELAAFTDGPEPVVLVSLGTLHAGSDAFFRACFEALGGLPARILLVAGSHTDPA
                     RLGKPPANTLIRASVPQLEVLRRAAAFVTHGGMNSALEGLACGVPLVVVPQQVEQLVIG
                     EAVAGRGAATVLRHNLSKRPVPVAELRAAVENALSGSSPREAAQAIGASLGEDGGAPAA
                     AEAIEDYLRTRHPG"
     gene            complement(16401..17009)
                     /locus_tag="HUW46_RS29605"
                     /old_locus_tag="HUW46_05874"
     CDS             complement(16401..17009)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942717.1"
                     /locus_tag="HUW46_RS29605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05874"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215542062.1"
                     /transl_table=11
                     /translation="MGSEGTARPPGRPRNARADEAILTAAIDLLLERGVAQVSVEQVAR
                     LAGVTRATVYRRFPDLTALLVRAIEWEYRDADEAAPEWPDVEAMVASWAVQLGGPRDRK
                     LMRRLYATVDDYPELLRTYAETRGRGGAEAVRATLDRARRAGQFPSQVDPVVLQQILSG
                     AALLYVSVHPDTSGEDAIRAYFIDVLRQAGYRQGAQHDD"
     misc_feature    complement(17009..17025)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            17157..17600
                     /locus_tag="HUW46_RS29610"
                     /old_locus_tag="HUW46_05875"
     CDS             17157..17600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331164.1"
                     /locus_tag="HUW46_RS29610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05875"
                     /product="DUF3574 domain-containing protein"
                     /protein_id="WP_215542063.1"
                     /transl_table=11
                     /translation="MEKSRRTASAAAAALVIGLGGGVASASATAQPATEPAAAVGTPSK
                     RTELYFGTEKPTGGVVTPEDFENFVDKEITPAFPDGLTKFTATGQWKRGAEIVKETTYV
                     VVLFYPLGNRKADGEIEEIRADYKKFFDQDSVARADDTQRVSF"
     gene            complement(17723..18268)
                     /locus_tag="HUW46_RS29615"
                     /old_locus_tag="HUW46_05876"
     CDS             complement(17723..18268)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05876"
                     /product="hypothetical protein"
                     /protein_id="WP_215542064.1"
                     /transl_table=11
                     /translation="MTKQYRIARPFSSARFGLFWLGIALVLGAVFLLGALGVLLDQKWI
                     TALGTALLIGGPAAAIRRYQRENTVLYLHPGNLGIGRWTVPWDAVEKIVLDHDRSPGSP
                     DTMVIGVRLRSRQAVPAGIRAGQLDQTTPNRPVVRLEARRSRVHEDLLARTLEKIGPSH
                     VTLISRTGGADTTLADRP"
     gene            complement(18341..18571)
                     /locus_tag="HUW46_RS29620"
                     /old_locus_tag="HUW46_05877"
     CDS             complement(18341..18571)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05877"
                     /product="hypothetical protein"
                     /protein_id="WP_215542065.1"
                     /transl_table=11
                     /translation="MSARTPEPGDEFSLSDPAYRQRLFGIALLLLGNTAAAQEALHAAA
                     CRVRLAAEQPGTDPALALPRSLIAEIRARPF"
     gene            complement(18568..19293)
                     /locus_tag="HUW46_RS29625"
                     /old_locus_tag="HUW46_05878"
     CDS             complement(18568..19293)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019265.4"
                     /locus_tag="HUW46_RS29625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05878"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_215542066.1"
                     /transl_table=11
                     /translation="MNTTVLPQNQLGEERPGMTFDDQAAGHDDALSALIGALLRDFAAA
                     PGRFAVPAPRGGITRVSGSTTAPDGGARFTGMLVELFDGSREAFTSYAREHLSDNRAEA
                     EDVVQTAFMRVFARKPEITEPESLRAYVWTSVKNATNDAMRRMIVTRERVEGDGDDKIA
                     VLRERAGLAVDELVLLRQYLLRLLDALQPRERETVVLHGFGGYTYKETAKIMGITEGAA
                     KKNVHTAVKRIEAFLKTAP"
     gene            complement(19330..20496)
                     /locus_tag="HUW46_RS29630"
                     /old_locus_tag="HUW46_05879"
     CDS             complement(19330..20496)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019348.4"
                     /locus_tag="HUW46_RS29630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05879"
                     /product="AAA family ATPase"
                     /protein_id="WP_215542067.1"
                     /transl_table=11
                     /translation="MRESTLAEVRRSAKEAALEAVRVHEKLVTDVARETATEAAAAIAR
                     RVSDRIERNDASVRRIAAATAKGTFEKLLSGWQPDRSETEVRAAKVAETTAKELLRDCA
                     GRMREVARDEAAKVCAEESPRIIQVDGHRPDPAEVSGDTHAVLPDLLLALRARCHVLLV
                     GPAGTGKSTMAEQAAEAFGLAFHALSLGPTTPMSKVFGYFDAHGHYHDTPFRRAFEHGG
                     LMLLDELDSGHPGLLAELNQALALGVCAFADGMVTAHRDFCLVATGNTYGTGGDRQYVG
                     RQALDAATLDRFAVLEVQVDERLERRVALAQAPSRQAEAVRILEEVRGLRAAATEKRLP
                     VMFSPRASIDAAKLLEAGATLAQARAWRVVRGISAAHREALGLDHPIE"
     gene            complement(20570..23095)
                     /locus_tag="HUW46_RS29635"
                     /old_locus_tag="HUW46_05880"
     CDS             complement(20570..23095)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044287.1"
                     /locus_tag="HUW46_RS29635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05880"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_215542068.1"
                     /transl_table=11
                     /translation="MADRSGDGHGPLGRAVVRVLGPDGTVAGAGFLLAPNVIATCAHVV
                     TAAVGGDPANWERPSAACTVDFPLVTGPGSRAKRFSAAVVTWLPILPDGTGDIALLELA
                     EPAPDAAQVPPLARVESAWGHEFRVLGFPGDFPDGVWSSGVFRDLQGTQWLQLEGTPGE
                     QPIVGGFSGSPVWDSDARAVVGMTVAAHAGPLVATAYLIPIERVFGTDPGRVPNPYRGL
                     EPFDERHADFFFGREDDLQRLSDAVARRPLVAVMGHSGTGKSSLIRAGMLPRLRAAGAA
                     IVPFRPMPGVTGPLSLALAMARLLHPDLPATDQFRWAQALAVRLPTDPGAVRWLANALL
                     EAGREAGMVLFLDQFEELAAEDLDAAKEFLRLLVRLLGAGGSVPLRVLVTLRWNAMGDL
                     LTEDTKDALGTAIVTLAPMGPAQLRAAIVGPSTRAPGLYFEDGLVDRILDDAGAEPGQL
                     PLVESLLTQLWEERDGGFMTTAAYTGIGGVAGAVTRAAESAIAEFVGRGEVEFLRRFFT
                     QLARPDGEQFSRRAVLMAALDPGLRRLAHHLAKSRLVVVGQGMDGEPHAELAHQALIDH
                     WPRLRGWLEDDRAFLHWRDHLDQQITRWAAADGARDLLPRGGSLSEARKWLGERGAELT
                     ARQRDFIRAGSRHRRWRLAAATGAAVLVVAATVVVTTVAVNQTRRPGGDAAPAAGGGLP
                     SSSAAPPSPSTGTPSSPPPSTSASPPPSSRVAPPSSASSAPPPPPPSTGPPSLVPGPVP
                     PSVSAQCRELYVCFWQGPDFTGEMVAMPMVHSSGATCHPLSFTARSIYSHANENQAVYA
                     GGTCAKEERQPVGMGMGYPNATVRSYHHS"
     gene            complement(23204..24010)
                     /locus_tag="HUW46_RS29640"
                     /old_locus_tag="HUW46_05881"
     CDS             complement(23204..24010)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05881"
                     /product="hypothetical protein"
                     /protein_id="WP_215542069.1"
                     /transl_table=11
                     /translation="MPSWTEFLDLARAPDSIPDGAGRHGDSRWAGASWDEALELAAAGW
                     TRALPEVDVGIAALRERSGDGLRSTTLLPCWDVTGGEVDVGAYLSGVPECMVDAVPSWT
                     SARGRVVTFLVPASCSHTVAHRTIRNRGIALAALCTAIIEAGHSVEIWSGFSARVGRER
                     FSAVAKVIPAGEPLDVGRLLFAMAHPAMLRRLWFGVWDSSARRSAALLKRSRYGIPHPS
                     RAEDLAEDIADPYVFPNLDRHDTRWATLDSARTWCEDLFRGLGLLN"
     gene            complement(24025..24450)
                     /locus_tag="HUW46_RS29645"
                     /old_locus_tag="HUW46_05882"
     CDS             complement(24025..24450)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05882"
                     /product="hypothetical protein"
                     /protein_id="WP_215542070.1"
                     /transl_table=11
                     /translation="MTAMPSRPLIRELLVCADLAGSLRRHRPGENAEFATLASAVFTVL
                     AARRFAMPGDRRIPAFVDSAPAWAGTHQRIDATAAVRLIRATLGATALLDGVPADSVTV
                     LHILLSRAIVAEHGATAVQIDAVLHAAEALATESGAR"
     gene            complement(24447..25022)
                     /locus_tag="HUW46_RS29650"
                     /old_locus_tag="HUW46_05883"
     CDS             complement(24447..25022)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05883"
                     /product="hypothetical protein"
                     /protein_id="WP_215542071.1"
                     /transl_table=11
                     /translation="MFWRLMIIIAVALGLPLCVPTAALASQCGQVSYGAADLSGFGCGD
                     IAALGAYTLLGLAIAADIAYAMWLLFHSRLTNNLPPLDGPKRKSRGTTSSREAGVEDEI
                     ESTEKKGSGSGTLVKFPETFEDAQRGLTRKPGVKGAPVQPAGPHPAAHDQPAAPADFTS
                     SVMVVTVSGICAVKKWQSIKDFFGGGPR"
     gene            complement(25007..26425)
                     /locus_tag="HUW46_RS29655"
                     /old_locus_tag="HUW46_05884"
     CDS             complement(25007..26425)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024760.4"
                     /locus_tag="HUW46_RS29655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05884"
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="WP_215542072.1"
                     /transl_table=11
                     /translation="MTAVLRRGGFAVRTTAAVWLATVVLATACLLLFPWWRGQLLMSFP
                     GDRYPTPGGMAATYLIGMAVGTGCGAALLVTGPAVIARFARDGERARKLVAANRCAALV
                     CATGMPVFPFAKVFLVNPAGTAMAVPGAVFAVWVLHRLPRFRRIPLRFSLLAFGWGVTF
                     AFTFGCLAQTAHSALALRSLSDDWVPADLGAQPASMVLAAPLWEECAKAAGVLVVFHLL
                     RRRFDGVLTGAVLGGMTGAGFNFAETARFAMANFDQAAFHVWVRQWAGGVLFGHVLFTG
                     LFGAAVGLASRYGGWAGRVVCVAAGFATAVLGHFFWNFASFNGGMPWHGGSQEAEVLLA
                     MPLNYATLSGPLLVVVGVALWLGARHEARALRAVLLVESATGLGAVTRAELPVLSHPRL
                     RIAERLRACQRYGVRGYVHFGRLRDRQLELAATRWRLARDPDPRPPASERALRTEISAL
                     RQRCTGEGLTCSGG"
     cand_cluster    25833..78329
                     /SMILES="NNC(CS)C(=O)CC(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="3"
                     /protoclusters="4"
                     /tool="antismash"
     protocluster    25833..78329
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[45832:58329](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      complement(45833..58329)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="3"
     protocluster    25833..73059
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[45832:53059](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="4"
                     /tool="antismash"
     proto_core      complement(45833..53059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="4"
     gene            complement(26422..26679)
                     /locus_tag="HUW46_RS29660"
                     /old_locus_tag="HUW46_05885"
     CDS             complement(26422..26679)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05885"
                     /product="hypothetical protein"
                     /protein_id="WP_215542073.1"
                     /transl_table=11
                     /translation="MVRTAAKDVADARTVSGDLTGLTGKLREIGGRLESGAAAVSDQEL
                     RGAALAVAGDLERLGDGPAALRGLTGLSRLREAVDRKCPA"
     misc_feature    26744..26759
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            complement(26850..28001)
                     /locus_tag="HUW46_RS29665"
                     /old_locus_tag="HUW46_05886"
     CDS             complement(26850..28001)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05886"
                     /product="hypothetical protein"
                     /protein_id="WP_215542074.1"
                     /transl_table=11
                     /translation="MRCGAVVVGLVCAGLVASCTNGSEPPPEVAGLPAQRPNSVEEFER
                     TAGSPPVWLGSELTVQSYEDGQGRLDGPFFAFGVEAFAVGKAIKGPVAASGIGERRAEP
                     GQELVVVAADSRVRAGQWVPDEDDPKPKAELVVGGAPTALHRIPLTPPKSGVDVKLDSA
                     VVVASVPAGAPVSIRVTDAGRTQTMDLRTGRRGPDAIAGYYRRNSAELTWTGHLSGGIS
                     TPLGGGRTPVEFAAGFKTMDPAHLTDKPTATLAPYTPRRGWAPPGGAWLVVPRPVVSRP
                     FDPFSPLFDLALSDPAVFSLRLPDGTAIPAEPGSTTMSTEVLGPWPLKSGGLMTFAVPA
                     EFQRGTVRASIGAAEVTATRLKKKAAGSWSPAPAPFDIPVDLG"
     misc_feature    complement(27906..27908)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    28075..28089
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            complement(28087..29538)
                     /locus_tag="HUW46_RS29670"
                     /old_locus_tag="HUW46_05887"
     CDS             complement(28087..29538)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (77-443). E-value:
                     1.3e-18. Score: 59.4. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29670_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="HUW46_RS29670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05887"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_215542075.1"
                     /sec_met_domain="PF00561 (E-value: 2.4e-22, bitscore: 78.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRAAVAAAVLVTGLVPAMPAAAQPGLPWAPCAEADLAKLGLD
                     CATLAVPLDHARPHGPTVTLALSRKKAAAPKGVLVVNPGGPGITGRAVAGTVAGAMPPD
                     LVASYDIIGIDPRGVGASTPSMSCDKDYFAPPWPDPVPSNAGEELRLLSRPLAYTMKCA
                     AKYGSLLPHMSTEDSARDLDDVRRALGQPTIDYLGYGYGTYVGSVYGTLFPGKLRRAVL
                     DSVARQDADWYRHYIEQEDPGFDARSKDFFAWVAGKDDVYHLGTAPETVAAAYYGARGA
                     VKAKPAGGVVGPFEFEATFHNVAWESGLWPFLANTLAAFHHGDEKAVVTAYQAIAAHHG
                     DNDYAVFTAVQCADTAWPRDWRQWHDDATKLHATAPFATWNNTWYLSPCAFWPRAPRTP
                     VPITGAGLPPALIVHATDDIALAYRDAQRLHATLPGSRLVTEQGGLNPAVTFLRGNPCV
                     DAPAAAYLATGKLPAADLSCPAPIG"
     aSDomain        complement(28210..29307)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29670_Abhydrolase_1.1"
                     /evalue="1.30E-18"
                     /label="HUW46_RS29670_Abhydrolase_1.1"
                     /locus_tag="HUW46_RS29670"
                     /protein_end="443"
                     /protein_start="77"
                     /score="59.4"
                     /tool="antismash"
                     /translation="VLVVNPGGPGITGRAVAGTVAGAMPPDLVASYDIIGIDPRGVGAS
                     TPSMSCDKDYFAPPWPDPVPSNAGEELRLLSRPLAYTMKCAAKYGSLLPHMSTEDSARD
                     LDDVRRALGQPTIDYLGYGYGTYVGSVYGTLFPGKLRRAVLDSVARQDADWYRHYIEQE
                     DPGFDARSKDFFAWVAGKDDVYHLGTAPETVAAAYYGARGAVKAKPAGGVVGPFEFEAT
                     FHNVAWESGLWPFLANTLAAFHHGDEKAVVTAYQAIAAHHGDNDYAVFTAVQCADTAWP
                     RDWRQWHDDATKLHATAPFATWNNTWYLSPCAFWPRAPRTPVPITGAGLPPALIVHATD
                     DIALAYRDAQRLHATLPGSRLVTEQG"
     gene            complement(29535..30860)
                     /locus_tag="HUW46_RS29675"
                     /old_locus_tag="HUW46_05888"
     CDS             complement(29535..30860)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801491.1"
                     /locus_tag="HUW46_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05888"
                     /product="cation:proton antiporter"
                     /protein_id="WP_254125014.1"
                     /transl_table=11
                     /translation="MIAATAVSASVAQPPPPIAADSLWLFLLQVGVLLTLALLFGRLAV
                     RFSLPPLVGELAAGVLLGPSLLGAAIPSVTSWLFPPDAQQAHLLDSVGQVGVVLLVGLT
                     GLTLELGQLRDQVKPASSVAVCGVLLPIGGGVLAGYLMPDRFLPGGVDRTVFALFLGVA
                     MGVTAIPVIAKTLADMNLLETRVGKLILTAGVFDDAIGWLLLSIVSAMAVAGVHPGSVL
                     MSISVLLGFLLAAGLVVRPLVRLALTRASRSSGPGPLIVTVVAVVSLGAAASQALKLEA
                     VFGAFVAGVVVGSCPGLDRARLEPLRIMVMSVLAPLFLATVGLRVDLTNLADAATLAMA
                     AVVLLVAAATKFGGGYAGGRIGGLAHWDALSVGAGLNARGVVGVVVASVGRGLGLLTPG
                     MYATVLLLAIATSLMAPVVLRSTIRRSTASAVDRPSTVEEHA"
     gene            complement(30857..32113)
                     /locus_tag="HUW46_RS29680"
                     /old_locus_tag="HUW46_05889"
     CDS             complement(30857..32113)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031971.1"
                     /locus_tag="HUW46_RS29680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05889"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_215542076.1"
                     /sec_met_domain="DAO (E-value: 2.3e-07, bitscore: 29.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Trp_halogenase (E-value: 2.2e-27,
                     bitscore: 95.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVEFDVVVVGGGPAGATTAGLLAQRGHRVLVLERELFPRYHIGE
                     SLITGMLSVFDELGVTERLERVGFPRKNGLSIVWGKNRDLWNVNFAEIDGPYDYSFHVR
                     RAEFDEILLDHARELGVTVVEEATVKEPLLENGRVTGVRYEAGGETTEARAPLVVDASG
                     QSRVLSRKLTTIEWAEDLRNLAYWTYFEDTADLPDGQLGNILVERVSHGWFWAIPVETE
                     TRRLSVGYVTPTASLVSGGPSIDELYEAGVAESKQLKRLLLGAKRVAEFRSTRDWSYRS
                     AAVTGPGWLSTGDASGFIDPLFSGGVCLAVLGADAAAKAVDTVLRRPDLADRALAAYAA
                     GVHNMVSSFLDYVRFFYDPTRDREDYFEQARSMADFNERYPNAREAFVAVISGRLAMSE
                     LFRIPGAEEEPALTGTVEP"
     gene            32284..32850
                     /locus_tag="HUW46_RS29685"
                     /old_locus_tag="HUW46_05890"
     CDS             32284..32850
                     /NRPS_PKS="Domain: oMT (36-137). E-value: 1.7e-22. Score:
                     71.0. Matches aSDomain: nrpspksdomains_HUW46_RS29685_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="HUW46_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05890"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_215542077.1"
                     /transl_table=11
                     /translation="MSHLYQEPNAYRRRLTIPFSGLHTRAAAHARSAAPESGAVLDIGC
                     GPGTLALRIARSRPDLRVSGVDPSAAMVDYAAKAASRRGFAGRVDFAVGQAARMPFEPG
                     SFDVVVSTMSFHHWAALPDVVRELRRVVRPGGRIFVYDMRAAYYDGLRSAVEAVAPEWT
                     FRRKFLWLRVFPSLMFGCAEISVPS"
     aSDomain        32392..32694
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29685_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.70E-22"
                     /label="HUW46_RS29685_oMT.1"
                     /locus_tag="HUW46_RS29685"
                     /protein_end="137"
                     /protein_start="36"
                     /score="71.0"
                     /tool="antismash"
                     /translation="SGAVLDIGCGPGTLALRIARSRPDLRVSGVDPSAAMVDYAAKAAS
                     RRGFAGRVDFAVGQAARMPFEPGSFDVVVSTMSFHHWAALPDVVRELRRVVRPGGR"
     gene            complement(32834..33865)
                     /locus_tag="HUW46_RS29690"
                     /old_locus_tag="HUW46_05891"
     CDS             complement(32834..33865)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.4"
                     /locus_tag="HUW46_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05891"
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="WP_215542078.1"
                     /sec_met_domain="ksIII (E-value: 9.4e-88, bitscore: 293.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPHGLFLRGIGVHLPEGRITADEAVAAGYCGAEQIAHSGLLSVA
                     AGDGTSGVDMAVAAGREALSDADVKPGDLDLLVHATMLPEGPDGWSPAGYVLRELGCDP
                     GPCHEVRQGCNGMFAAMELAAGWLALSEHAATALLTTALRGESPLMDRWRSAGFGMHVG
                     DAGCAVLLGREHGIARVDAVCSTTFPELEGLHRGAAPPSEETAVRDGPIDVVTRSGEFV
                     AAAGYDPFELRRMFTAMYFSAARQAMAEAEVDAGELARVVFVNAGAPFVDLGIMQPLGL
                     PMAKSTWDFGRTVGHLGACDQVVSLHHLLATGQLSAGDRVLMVGGTQGYNAASAVLTVT
                     TER"
     gene            complement(33874..35214)
                     /locus_tag="HUW46_RS29695"
                     /old_locus_tag="HUW46_05892"
     CDS             complement(33874..35214)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     flavin-dependent pyrrole halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099830.1"
                     /locus_tag="HUW46_RS29695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05892"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_215542079.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-07, bitscore:
                     30.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 7.3e-07, bitscore: 28.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Trp_halogenase (E-value: 6.4e-24,
                     bitscore: 83.7, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADFDVAVIGGGPAGSTAAAYLAKAGLSVLLLESEIFPRPHVGE
                     SLVPAATPPLVESGAMPAVDAAGFPKKYGAAWTTANSVSLPNNGFAGLSHNLPAVVQFV
                     ERDQEGVDRDYTYHVDRGKFDLILLKNAEAQGAKVVCGARVLNVDFSDDQVVTLNCRIA
                     GANVTYTANLVVDASGRQTLLGKQLKTKIPDPVFNQYALHAWFEDFDRTAFVTEDHEED
                     FIYVHWLAMRDSWVWQIPITDTVTSFGVVTQKKNFTSASASPDELFWDFVDTRPELSKA
                     LRKARQIRPFKAEGDYSYRMREMAGDRFVLIGDAARFVDPIFSSGVSVAMNSARLVSRD
                     IIAAHEGGHGFGRSSFATYEAKLKKAVGYWYEFIAIFYRLNVLFTAFVKDPRYRIDVLR
                     MLQGDVYDGEPPKALEDMREILKAVENDPDHVWHPYLGAVWAGPGQA"
     gene            35334..36476
                     /locus_tag="HUW46_RS29700"
                     /old_locus_tag="HUW46_05893"
     CDS             35334..36476
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455421.1"
                     /locus_tag="HUW46_RS29700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05893"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_215542080.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1e-11, bitscore:
                     44.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-21, bitscore:
                     75.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.6e-37, bitscore:
                     126.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFDLAPEQQKRVDALRTAVRTGLPGAVRSSPDAHFSRTEWAAAA
                     ALGLTGLCLPSAFGGGGLGALDVALCLEAFGDECADTGLVFGVAAHLLACVVPIRDFAS
                     GSLLDELAPGLADGSVIAANAMTEPEAGSDVGALTTTATRADGGYRLDGVKSFASNGPL
                     ADVFVTYAVTDPDAAFLGISAFAVPRGVPGLKIGGPVAKTGLWGCPAGRVEFDGCFVPE
                     RYRLGEEGQGSGVFQHSMGWERACLFGLYLGVLARQLRQCVDHARTRRQFGRPIGEFQA
                     VSHRIADMRARLEAARLLVHRACWLLDENREHRAAAAVSKMTVSETAIANSLDAVRIFG
                     GAGYLGGDSAGTQLRDCVPTAIFSGTTDMQKEILTREMGL"
     gene            36473..37960
                     /locus_tag="HUW46_RS29705"
                     /old_locus_tag="HUW46_05894"
     CDS             36473..37960
                     /NRPS_PKS="Domain: AMP-binding (8-393). E-value: 1.2e-93.
                     Score: 305.9. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29705_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000110: Other (60% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005455420.1"
                     /locus_tag="HUW46_RS29705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05894"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_254125016.1"
                     /sec_met_domain="AMP-binding (E-value: 6.5e-97, bitscore:
                     323.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLHEAVRATAKRHPGRVAVSGVDGSLSYAELDRRADALAASFV
                     AAGVVPGDRVLIWAAKSCAVVVAMQAALRAGAAYVPVDSTSPAGRVATVVRDCAPRVVC
                     ASPDRAEEIARFLEEMPVFCDLGDLPEAAAPVAVAGGEDDLAFILYTSGSTGTPKGVCL
                     SHANAMAFVRWAIAELALGKEDRLANHAPFSFDLSVLDLYGALCTGGSVHLVAAELAYA
                     PEQLVDFLRWREITVWYSVPSALLLMMRDGGLLDRPAPAALRAVLFAGEPFPIGALRDL
                     AGWTGARLLNLYGPTETNVCTAHEVGEDDLARDRPVPIGTAVSGDTVWAVVDGEVARPG
                     EAGELHVSGPSVMRGYWGREPQRDPYPTGDLVSVREDGSFEYLGRRDAMVKVRGHRVEL
                     GDVEAALTAHPDIAEAAAVVRGSALGGRIEAFVVPRPGARLGVLAVKRHCAERLPTYMI
                     ADDAHFVPALPRTANGKVDRAALAVRHPSNPKEGSTV"
     aSDomain        36497..37651
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29705_AMP-binding.1"
                     /evalue="1.20E-93"
                     /label="HUW46_RS29705_AMP-binding.1"
                     /locus_tag="HUW46_RS29705"
                     /protein_end="393"
                     /protein_start="8"
                     /score="305.9"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="RATAKRHPGRVAVSGVDGSLSYAELDRRADALAASFVAAGVVPGD
                     RVLIWAAKSCAVVVAMQAALRAGAAYVPVDSTSPAGRVATVVRDCAPRVVCASPDRAEE
                     IARFLEEMPVFCDLGDLPEAAAPVAVAGGEDDLAFILYTSGSTGTPKGVCLSHANAMAF
                     VRWAIAELALGKEDRLANHAPFSFDLSVLDLYGALCTGGSVHLVAAELAYAPEQLVDFL
                     RWREITVWYSVPSALLLMMRDGGLLDRPAPAALRAVLFAGEPFPIGALRDLAGWTGARL
                     LNLYGPTETNVCTAHEVGEDDLARDRPVPIGTAVSGDTVWAVVDGEVARPGEAGELHVS
                     GPSVMRGYWGREPQRDPYPTGDLVSVREDGSFEYLGRRDAMVKVR"
     CDS_motif       36683..36721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29705_0001"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29705"
                     /protein_end="83"
                     /protein_start="70"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AALRAGAAYVPVD"
     CDS_motif       36908..36967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29705_0002"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29705"
                     /protein_end="165"
                     /protein_start="145"
                     /score="30.3"
                     /tool="antismash"
                     /translation="AFILYTSGSTGTPKGVCLSH"
     CDS_motif       37487..37552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29705_0003"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS29705"
                     /protein_end="360"
                     /protein_start="338"
                     /score="29.6"
                     /tool="antismash"
                     /translation="PGEAGELHVSGPSVMRGYWGRE"
     CDS_motif       37616..37681
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29705_0004"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="HUW46_RS29705"
                     /protein_end="403"
                     /protein_start="381"
                     /score="33.0"
                     /tool="antismash"
                     /translation="YLGRRDAMVKVRGHRVELGDVE"
     gene            37957..38253
                     /locus_tag="HUW46_RS29710"
                     /old_locus_tag="HUW46_05895"
     CDS             37957..38253
                     /NRPS_PKS="Domain: PP-binding (19-75). E-value: 3e-07.
                     Score: 22.7. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29710_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="HUW46_RS29710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05895"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_215542081.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-05, bitscore:
                     24.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVTEDRLIDFIREKFLAGDPDGELTAESPLLQWGILDSLKVAI
                     LLTFIREQLGVIVPFQHLSAKNFGTVRSMAVLVTELGEPAPDHADSVHSIPPS"
     aSDomain        38014..38181
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29710_PP-binding.1"
                     /evalue="3.00E-07"
                     /label="HUW46_RS29710_PP-binding.1"
                     /locus_tag="HUW46_RS29710"
                     /protein_end="75"
                     /protein_start="19"
                     /score="22.7"
                     /tool="antismash"
                     /translation="GDPDGELTAESPLLQWGILDSLKVAILLTFIREQLGVIVPFQHLS
                     AKNFGTVRSMA"
     gene            complement(38217..39014)
                     /locus_tag="HUW46_RS29715"
                     /old_locus_tag="HUW46_05896"
     CDS             complement(38217..39014)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="HUW46_RS29715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05896"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_215542082.1"
                     /transl_table=11
                     /translation="MRYELLGPVRLADRGRTTAVGPRRVQTVLSVLLIRAGEMVTRDQL
                     IAEIWADDPPRQATAAVHVYLSKLRKALTAAGCPGGTVLTHETGYVLRTGTDEVDFDIV
                     LRLASRGRALMRHGRFTDAIRVLEGALALWRGPVLGGLRAGHVVDGFVTQLTETRLSCL
                     EMLIDCRLERGLHRELVGPLHSIVAEHPMRETFHRQLMVALYRSDRQADALNVYHLARK
                     TLDDQLGVRPGKMLQRTQQAILRADDELLARCHDGGMEWTESA"
     gene            complement(39025..40524)
                     /locus_tag="HUW46_RS29720"
                     /old_locus_tag="HUW46_05897"
     CDS             complement(39025..40524)
                     /NRPS_PKS="Domain: AMP-binding (6-395). E-value: 4.3e-90.
                     Score: 294.2. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29720_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="HUW46_RS29720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05897"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_215542083.1"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-82, bitscore:
                     274.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLYERFENQVLIDPGQVALVDGELSLTYRELRSAAEDLRDRLAA
                     AGARPGDLIGLRMPRGVPVAVGILGILAHGCAYVPLDPAYPAARTKLIADDARITLTVV
                     GGRDSWQPEVVVTGERRDRHDVPPGTAYVIYTSGSTGRPKGVFVGNEHVLALMDSGNKV
                     FDFDASDVWSVFCGYGFDVSVWELWGALLNGGTAVMISRETAADPRAFSEVLLAEEVTV
                     LNQVPTAFGYLVAELEAREVRLPALRYVIFSGEAIQLPAIRRWHELGAAPAATLVNMYG
                     ITETTVHATHQVLTPDDTGEPAWPGSTPIGIPLPHLEITVVDEDLRPVPAGTPGQLLVS
                     GAGVTHGYLGRADLTAERFTVYNGLRTFRSGDWAVLDESGGLHYLGRKDRQVQIRGFRV
                     ELGEVEAAIAGHPLLAQCAVTVATNSHGEPLLTAHYTRVGGDEPTGDLLRRFAAGVLPP
                     HMVPMAFRAHAAMPTTQHGKVDLAALDATPPTGSETTENTR"
     CDS_motif       complement(39310..39375)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29720_0005"
                     /evalue="6.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="405"
                     /protein_start="383"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YLGRKDRQVQIRGFRVELGEVE"
     aSDomain        complement(39340..40506)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29720_AMP-binding.1"
                     /evalue="4.30E-90"
                     /label="HUW46_RS29720_AMP-binding.1"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="395"
                     /protein_start="6"
                     /score="294.2"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FENQVLIDPGQVALVDGELSLTYRELRSAAEDLRDRLAAAGARPG
                     DLIGLRMPRGVPVAVGILGILAHGCAYVPLDPAYPAARTKLIADDARITLTVVGGRDSW
                     QPEVVVTGERRDRHDVPPGTAYVIYTSGSTGRPKGVFVGNEHVLALMDSGNKVFDFDAS
                     DVWSVFCGYGFDVSVWELWGALLNGGTAVMISRETAADPRAFSEVLLAEEVTVLNQVPT
                     AFGYLVAELEAREVRLPALRYVIFSGEAIQLPAIRRWHELGAAPAATLVNMYGITETTV
                     HATHQVLTPDDTGEPAWPGSTPIGIPLPHLEITVVDEDLRPVPAGTPGQLLVSGAGVTH
                     GYLGRADLTAERFTVYNGLRTFRSGDWAVLDESGGLHYLGRKDRQVQIR"
     CDS_motif       complement(39448..39537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29720_0004"
                     /evalue="1.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="359"
                     /protein_start="329"
                     /score="42.9"
                     /tool="antismash"
                     /translation="PAGTPGQLLVSGAGVTHGYLGRADLTAERF"
     CDS_motif       complement(39925..39963)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29720_0003"
                     /evalue="5.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="200"
                     /protein_start="187"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="WGALLNGGTAVMI"
     CDS_motif       complement(40081..40134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29720_0002"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="148"
                     /protein_start="130"
                     /score="29.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVFV"
     CDS_motif       complement(40279..40320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29720_0001"
                     /evalue="9.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29720"
                     /protein_end="82"
                     /protein_start="68"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LGILAHGCAYVPLD"
     gene            complement(40533..41597)
                     /locus_tag="HUW46_RS29725"
                     /old_locus_tag="HUW46_05898"
     CDS             complement(40533..41597)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: nMT (39-249). E-value: 1.6e-89. Score:
                     291.8. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29725_nMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="HUW46_RS29725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05898"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_215542084.1"
                     /transl_table=11
                     /translation="MSVHHDHVRGWEAVYDELYAGSLGEDPDSRFAGWTSSYTGEPIPL
                     AEMREWRDATVRRIRALRPKRVLEIGVGSGLLLTELAPRCDSYWGIDASGAAIDWLDDT
                     LEDDLADRVVVRQCAAHELTELPEGFFDTVILNSVVQYFPGTGYLREVLDGVFRLLAPG
                     GSVFVGDVRNPRSHRSFQAAIAVARGEQGAAALARADRALGMAEELLVDPGFFAGLPGT
                     ADIRLKEALHHNELSRHRYDVVLTRSHRDTPAAPELVWGNDLRSAAELRGRLDGTELVV
                     RGIPNLRLTEEDAALAALESRPPPPPGVDPEELSALGAGLGYRVLATVSDMDGGWFDVL
                     FTKDPESVAPFRER"
     aSDomain        complement(40851..41480)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29725_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="1.60E-89"
                     /label="HUW46_RS29725_nMT.1"
                     /locus_tag="HUW46_RS29725"
                     /protein_end="249"
                     /protein_start="39"
                     /score="291.8"
                     /tool="antismash"
                     /translation="GEPIPLAEMREWRDATVRRIRALRPKRVLEIGVGSGLLLTELAPR
                     CDSYWGIDASGAAIDWLDDTLEDDLADRVVVRQCAAHELTELPEGFFDTVILNSVVQYF
                     PGTGYLREVLDGVFRLLAPGGSVFVGDVRNPRSHRSFQAAIAVARGEQGAAALARADRA
                     LGMAEELLVDPGFFAGLPGTADIRLKEALHHNELSRHRYDVVLTRSH"
     gene            complement(41597..44602)
                     /locus_tag="HUW46_RS29730"
                     /old_locus_tag="HUW46_05899"
     CDS             complement(41597..44602)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (1-28). E-value: 2e-11.
                     Score: 34.9. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29730_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (6-305). E-value:
                     2.7e-87. Score: 284.6. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29730_Condensation_DCL.1"
                     /NRPS_PKS="Domain: PCP (531-599). E-value: 1.3e-17. Score:
                     55.7. Matches aSDomain: nrpspksdomains_HUW46_RS29730_PCP.1"
                     /NRPS_PKS="Domain: TD (638-872). E-value: 2.8e-68. Score:
                     221.7. Matches aSDomain: nrpspksdomains_HUW46_RS29730_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="HUW46_RS29730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05899"
                     /product="thioester reductase domain-containing protein"
                     /protein_id="WP_215542085.1"
                     /sec_met_domain="Condensation (E-value: 3.5e-56, bitscore:
                     189.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-10, bitscore:
                     40.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.4e-52, bitscore:
                     175.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAREIEDVYDLTPLQHGMLFENLYAPGEGTYLEQSVLEFEGALD
                     TDAYWRAWQHVVDRHPALRTTFHWNDIKKPVQTVHRRIGLPRTELDLRGLGAAEGQDRI
                     ADYLRPVRANGFDLEARPPMDLCLAVGDDRWHQLLSVHHLILDGWSVGIIMGEFLRAYR
                     ACCDGHEPGLPPAGRFRDYVAWWRRQDGAEAGRYWRDQLAGYTPPPRLDVGTPPAVRTG
                     EIPYDWAELDLADVAEDVHAFAKRHRLTANTLVHGAWSLVLARCQHTDDLTVGTTFAHR
                     PADVPAAESIVGCLVGTFPIRTRPREDQPVLDYLGHVQDSVLAAREHTATDLVGIQRHS
                     GVARAGGLFESLVTYQNIPIPEFGGPVGGIRIRGYTVDTRPQLPLVLMVMPGTTMPMRL
                     VHDRRRFGAHQAGLLLARVRHVLAAIVASDAGTTLADIDVRPEDERRRIARACADPANL
                     AAALPAGRPLRLVDARGHEVPLGAPGLVEIGGAVSGLWARVTDDDGLEHLGDRAETTAP
                     AAESGPADPPATPTEKAVAELMAAILDVDRVGAADNLVELGLHSLLGTRATNQIRDRWN
                     LTVTLHALFENPTVRDLAKLIEAGGEAQPAPRGHQDLSADVTLDESITGIGPAAWHPSP
                     SRFLLTGATGYLGSFLLDRLLRSGTATVTCLVRDRTPDDGLARVHDTLRAAGLWREEYR
                     GRITTVCGNLTKPLLGLSEENFAALAADVQEIYHAGGTVNTLPSYRRLRSTNVGGTKEV
                     LRLAATGRTKPVHYPSYAGLSAPELGGRELPVTGTPPEARHGYEASKWVAERLLALADE
                     RGVPTVVYRAARLVGATSPAYWNPSDATSEIVQACAYLGMVPDSAVPMPASPVDYVADG
                     ITALARKKESLGGRYHLISPQPFTFRVVGEAMTLAGYDLRSVDIDTWYSELVRRSAEDG
                     GRRWDLVLSVVGAWKRQVADGWREAEYDTSRARSALSADLVCGPVDAAYLRGALACFAS
                     TGHLPAPAGANG"
     aSDomain        complement(41987..42688)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29730_TD.1"
                     /evalue="2.80E-68"
                     /label="HUW46_RS29730_TD.1"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="872"
                     /protein_start="638"
                     /score="221.7"
                     /tool="antismash"
                     /translation="LLTGATGYLGSFLLDRLLRSGTATVTCLVRDRTPDDGLARVHDTL
                     RAAGLWREEYRGRITTVCGNLTKPLLGLSEENFAALAADVQEIYHAGGTVNTLPSYRRL
                     RSTNVGGTKEVLRLAATGRTKPVHYPSYAGLSAPELGGRELPVTGTPPEARHGYEASKW
                     VAERLLALADERGVPTVVYRAARLVGATSPAYWNPSDATSEIVQACAYLGMVPDSAVPM
                     PASPVDYVADGI"
     aSModule        complement(41987..44584)
                     /domains="nrpspksdomains_HUW46_RS29730_Condensation_DCL.1"
                     /domains="nrpspksdomains_HUW46_RS29730_PCP.1"
                     /domains="nrpspksdomains_HUW46_RS29730_TD.1"
                     /final_module
                     /incomplete
                     /locus_tags="HUW46_RS29730"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(42806..43009)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29730_PCP.1"
                     /evalue="1.30E-17"
                     /label="HUW46_RS29730_PCP.1"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="599"
                     /protein_start="531"
                     /score="55.7"
                     /tool="antismash"
                     /translation="EKAVAELMAAILDVDRVGAADNLVELGLHSLLGTRATNQIRDRWN
                     LTVTLHALFENPTVRDLAKLIEA"
     CDS_motif       complement(43526..43648)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29730_0005"
                     /evalue="1.70E-07"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="359"
                     /protein_start="318"
                     /score="23.6"
                     /tool="antismash"
                     /translation="QDSVLAAREHTATDLVGIQRHSGVARAGGLFESLVTYQNIP"
     aSDomain        complement(43688..44584)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29730_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.70E-87"
                     /label="HUW46_RS29730_Condensation_DCL.1"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="305"
                     /protein_start="6"
                     /score="284.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLILDG"
                     /tool="antismash"
                     /translation="EDVYDLTPLQHGMLFENLYAPGEGTYLEQSVLEFEGALDTDAYWR
                     AWQHVVDRHPALRTTFHWNDIKKPVQTVHRRIGLPRTELDLRGLGAAEGQDRIADYLRP
                     VRANGFDLEARPPMDLCLAVGDDRWHQLLSVHHLILDGWSVGIIMGEFLRAYRACCDGH
                     EPGLPPAGRFRDYVAWWRRQDGAEAGRYWRDQLAGYTPPPRLDVGTPPAVRTGEIPYDW
                     AELDLADVAEDVHAFAKRHRLTANTLVHGAWSLVLARCQHTDDLTVGTTFAHRPADVPA
                     AESIVGCLVGTFPIRTRP"
     CDS_motif       complement(43697..43792)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29730_0004"
                     /evalue="2.40E-09"
                     /label="C5_DCL_263-294"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="302"
                     /protein_start="270"
                     /score="29.6"
                     /tool="antismash"
                     /translation="DLTVGTTFAHRPADVPAAESIVGCLVGTFPIR"
     cand_cluster    43923..85973
                     /candidate_cluster_number="5"
                     /contig_edge="False"
                     /detection_rules="(APH and HopA1)"
                     /kind="single"
                     /product="lanthipeptide-class-v"
                     /protoclusters="5"
                     /tool="antismash"
     protocluster    43923..85973
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[63922:65973](-)"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="5"
                     /tool="antismash"
     proto_core      complement(63923..65973)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="5"
     CDS_motif       complement(44117..44182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29730_0003"
                     /evalue="4.80E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="162"
                     /protein_start="140"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VHHLILDGWSVGIIMGEFLRAY"
     CDS_motif       complement(44396..44515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29730_0002"
                     /evalue="3.50E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="69"
                     /protein_start="29"
                     /score="54.7"
                     /tool="antismash"
                     /translation="GTYLEQSVLEFEGALDTDAYWRAWQHVVDRHPALRTTFHW"
     aSDomain        complement(44519..44599)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29730_NRPS-COM_Nterm.1"
                     /evalue="2.00E-11"
                     /label="HUW46_RS29730_NRPS-COM_Nterm.1"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="28"
                     /protein_start="1"
                     /score="34.9"
                     /tool="antismash"
                     /translation="SAREIEDVYDLTPLQHGMLFENLYAPG"
     CDS_motif       complement(44540..44575)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29730_0001"
                     /evalue="2.50E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="HUW46_RS29730"
                     /protein_end="21"
                     /protein_start="9"
                     /score="10.9"
                     /tool="antismash"
                     /translation="YDLTPLQHGMLF"
     misc_feature    44635..44646
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(44676..45836)
                     /locus_tag="HUW46_RS29735"
                     /old_locus_tag="HUW46_05900"
     CDS             complement(44676..45836)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102878.1"
                     /locus_tag="HUW46_RS29735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05900"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_254125017.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.8e-27, bitscore:
                     93.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.4e-20, bitscore:
                     72.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.3e-42, bitscore:
                     142.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPVEPDPARRAEIREFANRAVRPLVSKMDTAQRMDDGLVQTLF
                     AEGLMGIEVPEAYGGYGGDLLSSAVAIEELSRVDPGVAVFVDVQNALVISALLRHGDGD
                     QKRRYLPRLATSTVGAYALSERDSGSDAFALTTEAVPDGTGFRLTGHKHWTTNAAEAGL
                     FVVFAKSGNSSATAFLVDADAPGVRVGERISKLGIRASSTCAVEFDDVLVGKENVLGGA
                     NNGRVIAMETLNIGKIGIAAQMIGLAQGALDAAFDYAQQRRQFGEPIISYQGVQFPLAR
                     LTAELDAARTYLYHTIAVLDAIPLAKRLTATATAKFLAAEVAERAASQAVETLGGNGYS
                     TEYPAEKLYRDAKIGKIYEGTTNMQLRAIAAARVSGGEHGDGAAPW"
     gene            complement(45833..53059)
                     /locus_tag="HUW46_RS29740"
                     /old_locus_tag="HUW46_05901"
     CDS             complement(45833..53059)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (9-433). E-value:
                     3.4e-154. Score: 505.7. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29740_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (528-803). E-value: 4.5e-95.
                     Score: 310.4. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29740_PKS_AT.1"
                     /NRPS_PKS="Domain: PCP (921-988). E-value: 4.8e-23. Score:
                     73.2. Matches aSDomain: nrpspksdomains_HUW46_RS29740_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (1009-1308). E-value:
                     6.6e-95. Score: 309.9. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29740_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1480-1873). E-value:
                     4.5e-95. Score: 310.6. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29740_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1987-2053). E-value: 3e-18. Score:
                     57.8. Matches aSDomain: nrpspksdomains_HUW46_RS29740_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="HUW46_RS29740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05901"
                     /product="non-ribosomal peptide synthetase/type I
                     polyketide synthase"
                     /protein_id="WP_215542086.1"
                     /sec_met_domain="hyb_KS (E-value: 1e-159, bitscore: 531.1,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 6.2e-67, bitscore:
                     224.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.1e-93, bitscore: 310.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-13, bitscore:
                     49.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.3e-40, bitscore:
                     137.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-106, bitscore:
                     354.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTNDGTEIAIIGKACRFPGANDQRQYWQNLREGKESVTFFDSE
                     ALRAAGVADELIDDPAYVKAFGALDDIDLFDAGFFGFSARDATVLDPQQRVLLETAWQA
                     LEDAGQRRFGDDVTVGVFAGSSMSTYLLANLLPGRAMDTSPDGFELLIANDKDYLASRI
                     AYKLDLDGPAVSVQTACSTSMVAVHLACQSLLSYDCDVALAGGATIRLPQHGYRYQEGM
                     ILSADGHCRPFDAKASGTIGGNGAGIVVLKRLDDALADGDRIDAVIKGSAVNNDGARKV
                     GYTAPGSTGQAKVVAAALGAAGIDPGTIGAIEAHGTGTALGDPIEIAALTKVFGPYHAG
                     GCPIGSVKSNIGHLDSAAGIAALIKAILQLQHREIAPSLNFEQENPDIGFDATPFFVNT
                     ELRPWQATGTPRRIGVSSFGFGGTNAHCVLEEAPAATRSTPGKPVQAIVLSARSAGALD
                     AMTGRIGRELRESGEPLADTAFSLQTTRTALPHRRVVLCSSAEDAAEAIENRDPQRVLS
                     RQAGDAPEVAWLFPGQGTQYPAMGRDLYRDEPVFRAGVDECAELLRPHLGLDLRDVLYA
                     EDGGDRIERTELAQPALFTVEYALAKTLESWCGKPKAMLGHSVGEVVAACLAGVFTLPD
                     ALHMVAVRGKLMQQQPSGAMLTVALSEDDLREVLVPSVEIAAINAPGQCAVAGTHDAID
                     EFAELLRERGIDFGRLHTSHAFHTAMMDPAVAPLTEALSRIPLSAPAIPFLSNRSGDWI
                     TAAQATDPAYWAGQVRDPVRFHACLRKLAADPGTVLLEAGPGHTLGSLSRMDPDLRGHV
                     LVNAMRAPAEEHSDTRFLLDAVGRLWLTGVEVDWAAMHEGEHRRLLSLPPYAFDRKRYW
                     IGAPAGGETPTRSLDSAIVSTVEEETEDEQSGGSRPDLLTAYAAPETEAQQRIARIWQD
                     LIGVGPIGIHDNFIELGGHSLLATKIVAGVRAEFAVDVPLRDLIAAPTVEAMAALVVEA
                     GGAPSERERLPVAVPDPAARYEPFPLSEIQQAQWIGRSANFSVGNVAAHIYWEVEDDRI
                     DLGRLGGSFNRILARHDMLRAIITSDGTQRILADAGPYEIDVLDLRTTPADRAAEELAL
                     VRERMSHEVRPGDEWPLFNIRAALLPGGLTRVFLGFDLMVSDMGSVRVMLRDWRTLYED
                     PSAELTPLRITFRDYLMAIGKLKESALYQRSLAYWRDRVRDLPPAPELPLATAPDTITE
                     PRFVPCSRTLPVAQWESIKERAGKYGVTPSAVLLAAYALVLGTWSTSEKFTLNVTTNNR
                     LPVHEDVGGLVGGFASFNLVPVDLAEHGTLGAIARAIQAQSWEDLDHRYVNGVDVLREL
                     ARARGGTSGSVMPIVYTSTLVDESETERSMVDWIGGLTYEVIQTPQVWLDAGVLEVSDG
                     LYLSWPAVEGLFAAGVVEEMFAAYCGVLELLAGGDSGWESGVDSVLPGWQREVIESVND
                     TAAPIDVQLLHGPLVECALADPSARAVFADGEWTTFGELYVRACRTARTLRSLGVGPGQ
                     VVAVSMDKTAAQITAVVAVLLAGGVYVPIDPELPTARRHHMATHAGARLILTTEARETL
                     DWPDNTRVALLDTAPVDLAEATRDATPEQVSQLDDLAYIIYTSGSTGLPKGVAITHRAA
                     SNTCLDINARFGVTSADRALALSSLSFDLSVWDVFGVLGAGGSLVLPATGRDPAHWHEL
                     ITTHDITVWNSVPALMTMYTEHLPTGTPATSLRLVMLSGDWIPLALPDNLWATHPDIDL
                     YSLGGATEAAIWSVYHPITALDPEWTSIPYGTPLANQQLHVLDTQLQPCPIHTTGDLYI
                     SGDGLATGYHNDPGKTHAAFLTHPTTGTRLYKTGDLARRHPDGTLEFLGRTDTQVKING
                     HRIELGEIETTLTTHPDIHTAIATTTGPPHHKQLHAYLYPHPHTTLTPEQLRTQTHHHL
                     TQTLPTYMHPTTTTILTHLPLTPNGKINRNHLPHPTTTTPETTTADAPLSELAVRLAAI
                     AAEVLGVEHIDARASFFEVGGDSITAVQIAARAGDQGVQLVLADLFEAETIADAAAIIE
                     ARATSLDGAGDAVELTPSQRALLDGAKPGGTANWVELPVDADFFVCPEWIEALLRRHPA
                     LRGRFERDGEDWVQRIGEAGTYVPEIDLRVLREDRQRGAMRQMVDEMREELDPREGGLV
                     KFAVFDLHDTRYLVCLAHELVADGRSWGALLGELAGLTGATEAAPARVTLGAEETATIL
                     TAAEETYRMSAEEVVLAACLDLLGGTGSTVHFEHDRREQPTAVGALGGIAEIGPVEPGT
                     ELPEVKRRYRSAVEAPAVHSPDVLVRSLGSVPCPVPAWPHWEPAGRAAAELTWAIADGG
                     LVVAWTGDAPATSTDFADAVRRVGQRCRGHEEIHVDTGDFPLADVDDEDLAAVFAEVSG
                     EFH"
     CDS_motif       complement(46451..46516)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0021"
                     /evalue="2.60E-04"
                     /label="NRPS-E2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="2203"
                     /protein_start="2181"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LVCLAHELVADGRSWGALLGEL"
     CDS_motif       complement(46700..46750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0020"
                     /evalue="8.30E-04"
                     /label="Cy2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="2120"
                     /protein_start="2103"
                     /score="12.0"
                     /tool="antismash"
                     /translation="LLRRHPALRGRFERDGE"
     aSDomain        complement(46901..47098)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_PCP.2"
                     /evalue="3.00E-18"
                     /label="HUW46_RS29740_PCP.2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="2053"
                     /protein_start="1987"
                     /score="57.8"
                     /tool="antismash"
                     /translation="RLAAIAAEVLGVEHIDARASFFEVGGDSITAVQIAARAGDQGVQL
                     VLADLFEAETIADAAAIIEAR"
     aSModule        complement(46901..50032)
                     /complete
                     /domains="nrpspksdomains_HUW46_RS29740_Heterocyclization.1"
                     /domains="nrpspksdomains_HUW46_RS29740_AMP-binding.1"
                     /domains="nrpspksdomains_HUW46_RS29740_PCP.2"
                     /locus_tags="HUW46_RS29740"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(47411..47476)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0019"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1883"
                     /protein_start="1861"
                     /score="36.6"
                     /tool="antismash"
                     /translation="FLGRTDTQVKINGHRIELGEIE"
     aSDomain        complement(47441..48619)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_AMP-binding.1"
                     /evalue="4.50E-95"
                     /label="HUW46_RS29740_AMP-binding.1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1873"
                     /protein_start="1480"
                     /score="310.6"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="ADPSARAVFADGEWTTFGELYVRACRTARTLRSLGVGPGQVVAVS
                     MDKTAAQITAVVAVLLAGGVYVPIDPELPTARRHHMATHAGARLILTTEARETLDWPDN
                     TRVALLDTAPVDLAEATRDATPEQVSQLDDLAYIIYTSGSTGLPKGVAITHRAASNTCL
                     DINARFGVTSADRALALSSLSFDLSVWDVFGVLGAGGSLVLPATGRDPAHWHELITTHD
                     ITVWNSVPALMTMYTEHLPTGTPATSLRLVMLSGDWIPLALPDNLWATHPDIDLYSLGG
                     ATEAAIWSVYHPITALDPEWTSIPYGTPLANQQLHVLDTQLQPCPIHTTGDLYISGDGL
                     ATGYHNDPGKTHAAFLTHPTTGTRLYKTGDLARRHPDGTLEFLGRTDTQVKIN"
     CDS_motif       complement(47555..47644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0018"
                     /evalue="1.80E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1835"
                     /protein_start="1805"
                     /score="36.2"
                     /tool="antismash"
                     /translation="PIHTTGDLYISGDGLATGYHNDPGKTHAAF"
     CDS_motif       complement(48155..48214)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0017"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1635"
                     /protein_start="1615"
                     /score="30.0"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGLPKGVAITH"
     CDS_motif       complement(48410..48448)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0016"
                     /evalue="1.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1550"
                     /protein_start="1537"
                     /score="12.3"
                     /tool="antismash"
                     /translation="AVLLAGGVYVPID"
     CDS_motif       complement(48455..48517)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0015"
                     /evalue="3.20E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1535"
                     /protein_start="1514"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="GVGPGQVVAVSMDKTAAQITA"
     CDS_motif       complement(48869..48904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0014"
                     /evalue="1.10E-03"
                     /label="Cy7"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1397"
                     /protein_start="1385"
                     /score="12.2"
                     /tool="antismash"
                     /translation="QTPQVWLDAGVL"
     CDS_motif       complement(49031..49078)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0013"
                     /evalue="9.70E-06"
                     /label="afterCy5"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1343"
                     /protein_start="1327"
                     /score="18.2"
                     /tool="antismash"
                     /translation="DLDHRYVNGVDVLREL"
     aSDomain        complement(49136..50032)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_Heterocyclization.
                     1"
                     /evalue="6.60E-95"
                     /label="HUW46_RS29740_Heterocyclization.1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1308"
                     /protein_start="1009"
                     /score="309.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DLMVSDM"
                     /tool="antismash"
                     /translation="YEPFPLSEIQQAQWIGRSANFSVGNVAAHIYWEVEDDRIDLGRLG
                     GSFNRILARHDMLRAIITSDGTQRILADAGPYEIDVLDLRTTPADRAAEELALVRERMS
                     HEVRPGDEWPLFNIRAALLPGGLTRVFLGFDLMVSDMGSVRVMLRDWRTLYEDPSAELT
                     PLRITFRDYLMAIGKLKESALYQRSLAYWRDRVRDLPPAPELPLATAPDTITEPRFVPC
                     SRTLPVAQWESIKERAGKYGVTPSAVLLAAYALVLGTWSTSEKFTLNVTTNNRLPVHED
                     VGGLVGGFASFNLVPVDL"
     CDS_motif       complement(49199..49237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0012"
                     /evalue="1.10E-02"
                     /label="afterCy4"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1287"
                     /protein_start="1274"
                     /score="8.8"
                     /tool="antismash"
                     /translation="FTLNVTTNNRLPV"
     CDS_motif       complement(49250..49309)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0011"
                     /evalue="3.10E-08"
                     /label="Cy4"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1270"
                     /protein_start="1250"
                     /score="26.3"
                     /tool="antismash"
                     /translation="GVTPSAVLLAAYALVLGTWS"
     CDS_motif       complement(49568..49621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0010"
                     /evalue="3.60E-01"
                     /label="C3_LCL_132-143"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1164"
                     /protein_start="1146"
                     /score="3.8"
                     /tool="antismash"
                     /translation="VSDMGSVRVMLRDWRTLY"
     CDS_motif       complement(49829..49876)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0009"
                     /evalue="1.00E-07"
                     /label="Cy2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="1077"
                     /protein_start="1061"
                     /score="24.2"
                     /tool="antismash"
                     /translation="ARHDMLRAIITSDGTQ"
     aSDomain        complement(50096..50296)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_PCP.1"
                     /evalue="4.80E-23"
                     /label="HUW46_RS29740_PCP.1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="988"
                     /protein_start="921"
                     /score="73.2"
                     /tool="antismash"
                     /translation="QRIARIWQDLIGVGPIGIHDNFIELGGHSLLATKIVAGVRAEFAV
                     DVPLRDLIAAPTVEAMAALVVE"
     aSModule        complement(50096..53032)
                     /complete
                     /domains="nrpspksdomains_HUW46_RS29740_PKS_KS.1"
                     /domains="nrpspksdomains_HUW46_RS29740_PKS_AT.1"
                     /domains="nrpspksdomains_HUW46_RS29740_PCP.1"
                     /locus_tags="HUW46_RS29740"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(50651..51475)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_PKS_AT.1"
                     /evalue="4.50E-95"
                     /label="HUW46_RS29740_PKS_AT.1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="803"
                     /protein_start="528"
                     /score="310.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGTQYPAMGRDLYRDEPVFRAGVDECAELLRPHLGLDLRDV
                     LYAEDGGDRIERTELAQPALFTVEYALAKTLESWCGKPKAMLGHSVGEVVAACLAGVFT
                     LPDALHMVAVRGKLMQQQPSGAMLTVALSEDDLREVLVPSVEIAAINAPGQCAVAGTHD
                     AIDEFAELLRERGIDFGRLHTSHAFHTAMMDPAVAPLTEALSRIPLSAPAIPFLSNRSG
                     DWITAAQATDPAYWAGQVRDPVRFHACLRKLAADPGTVLLEAGPGHTLGSLSR"
     CDS_motif       complement(50738..50773)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0008"
                     /evalue="7.00E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="774"
                     /protein_start="762"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YWAGQVRDPVRF"
     CDS_motif       complement(51116..51232)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0007"
                     /evalue="5.00E-24"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="648"
                     /protein_start="609"
                     /score="76.7"
                     /tool="antismash"
                     /translation="KPKAMLGHSVGEVVAACLAGVFTLPDALHMVAVRGKLMQ"
     CDS_motif       complement(51257..51292)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0006"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="601"
                     /protein_start="589"
                     /score="11.7"
                     /tool="antismash"
                     /translation="QPALFTVEYALA"
     CDS_motif       complement(51425..51472)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0005"
                     /evalue="8.90E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="545"
                     /protein_start="529"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FPGQGTQYPAMGRDLY"
     aSDomain        complement(51761..53032)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29740_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.40E-154"
                     /label="HUW46_RS29740_PKS_KS.1"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="433"
                     /protein_start="9"
                     /score="505.7"
                     /tool="antismash"
                     /translation="IAIIGKACRFPGANDQRQYWQNLREGKESVTFFDSEALRAAGVAD
                     ELIDDPAYVKAFGALDDIDLFDAGFFGFSARDATVLDPQQRVLLETAWQALEDAGQRRF
                     GDDVTVGVFAGSSMSTYLLANLLPGRAMDTSPDGFELLIANDKDYLASRIAYKLDLDGP
                     AVSVQTACSTSMVAVHLACQSLLSYDCDVALAGGATIRLPQHGYRYQEGMILSADGHCR
                     PFDAKASGTIGGNGAGIVVLKRLDDALADGDRIDAVIKGSAVNNDGARKVGYTAPGSTG
                     QAKVVAAALGAAGIDPGTIGAIEAHGTGTALGDPIEIAALTKVFGPYHAGGCPIGSVKS
                     NIGHLDSAAGIAALIKAILQLQHREIAPSLNFEQENPDIGFDATPFFVNTELRPWQATG
                     TPRRIGVSSFGFGGTNAHCVLEEAP"
     CDS_motif       complement(51983..52027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0004"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="359"
                     /protein_start="344"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GSVKSNIGHLDSAAG"
     CDS_motif       complement(52082..52126)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0003"
                     /evalue="8.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="326"
                     /protein_start="311"
                     /score="11.7"
                     /tool="antismash"
                     /translation="IEAHGTGTALGDPIE"
     CDS_motif       complement(52172..52204)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0002"
                     /evalue="5.70E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="296"
                     /protein_start="285"
                     /score="0.8"
                     /tool="antismash"
                     /translation="PGSTGQAKVVA"
     CDS_motif       complement(52502..52549)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29740_0001"
                     /evalue="6.40E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="HUW46_RS29740"
                     /protein_end="186"
                     /protein_start="170"
                     /score="15.3"
                     /tool="antismash"
                     /translation="GPAVSVQTACSTSMVA"
     gene            complement(53056..58329)
                     /locus_tag="HUW46_RS29745"
                     /old_locus_tag="HUW46_05902"
     CDS             complement(53056..58329)
                     /NRPS_PKS="Domain: CAL_domain (45-481). E-value: 3.1e-99.
                     Score: 324.3. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29745_CAL_domain.1"
                     /NRPS_PKS="Domain: PP-binding (593-654). E-value: 4.2e-09.
                     Score: 28.6. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29745_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (683-980). E-value:
                     1.5e-101. Score: 331.7. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29745_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1150-1543). E-value:
                     2.7e-95. Score: 311.3. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29745_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1656-1719). E-value:
                     5.7e-15. Score: 47.4. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29745_PP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="HUW46_RS29745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05902"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_215542087.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 2e-180, bitscore:
                     601.0, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.5e-46, bitscore:
                     155.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-106, bitscore:
                     355.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.7e-12, bitscore:
                     46.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPARAENAPTIIDVLARNAGEEPDRTAFSFADGPDSPAADSLSTR
                     DLHIRALAVAEALRTASAPGARILVLTPSARDYVIAVCGCLYAGRCAVPLGYAGTPVSS
                     AMAAAVGRDAGAEAILTSTAVAAEAKRRWQSAGGDAIAWLAVDELVRPSAADQAPARCA
                     PEDLAMLLYTSGSTGDPKGVLNSHASILAGIRKMVRMTGIPAGATVVNWVPVHHGIGLI
                     GHLLLSQYLGGDCSVLRTEDVVARPASWLEAISAANSPVFGGGPNFVYDRCTDFVTAEE
                     FAGLDLDNWHSALVAGERIRKNTLERFTARFGARGFARDSMFSVYGLTETTLLVSGRRA
                     GDIGSLALDRAALEAHTARIVPESDDTAIDLVSCGDPGPATTIRVVDPETRTEVAPGRV
                     GEIWAQGPFTAPGYWRRPRETAAVFDASLANGEGPFVRTGDLGFRHDGELFVCGRLKEL
                     LIIRGRNLYPQDIETTAAGVHPATTAAPAAAFAVEGEESERLVLVQAVRSPEELDAERL
                     AGDLRAAVTANHRVDAEVLVVAASAVPTTNAGKIRRAACREAYLEGRLAPLATSVPGGL
                     TVPAADATVGTAAVPVVVRRLLEDVLGGDAPEDVLASDATLAGLGLDSLRGMLVRHRLA
                     QETGVRLALDELLLASAREVTAKILAQSEMDTASPAPAPVVVPDPAARYEPFPLTGLQQ
                     AYVTGRDDVYELGGVATHYYREFDSETLDVDRFLGSLEKLVQRHEMLHATVSADGTQRV
                     LRDHAVPVTVDDLRHLDGTAAAERLDRTRAAMSHHVMPLEDGPLFEVRISRLTKSKVRV
                     HIGVDLLIADVRSIQIFYDDWELLYNGKELAPLTGEVSFRDYLIATERDADDAEYRRAR
                     DYWMDRIDTMPGAPRLPVVERAKNAKSRFRRIESQLDAGTWTRITNRAGKYGVTPSAVL
                     LAAYAVVLRTWSGSERFLLNIPMFNRQPLHHRIDEVIGDFTTILPLAVDARGDHGIAEL
                     AIRIQRQLLSDMDHRRFSGIEVLRELALRDGAATSAVAPVVFASGRGQGRGYLTGEWIG
                     EPGYAISQTPQVWVDNQTYEKDGELHFNWDTVEGLFPVGVVEEMFAAYCGVLELLAGGD
                     SGWESGVDSVLPGWQREVIESVNDTAAPIDVQLLHGPLVECALADPSARAVFADGEWTT
                     FGELYVRACRTARTLRSLGVGPGQVVAVSMDKTAAQITAVVAVLLAGGVYVPIDPELPT
                     ARRHHMATHAGARLILTTEARETLDWPDNTRVALLDTAPVDLAEATRDATPEQVSQLDD
                     LAYIIYTSGSTGLPKGVAITHRAASNTCLDINARFGVTSADRALALSSLSFDLSVWDVF
                     GVLGAGGSLVLPATGRDPAHWHELITTHDITVWNSVPALMTMYTEHLPTGTPATSLRLV
                     MLSGDWIPLALPDNLWATHPDIDLYSLGGATEAAIWSVYHPITALDPEWTSIPYGTPLA
                     NQQLHVLDTQLQPCPIHTTGDLYISGDGLATGYHNDPGKTHAAFLTHPTTGTRLYKTGD
                     LARRHPDGTLEFLGRTDTQVKINGHRIELGEIETTLTTHPDIHTAIATTTGPPHHKQLH
                     AYLYPHPHTTLTPEQLRTQTHHHLTHHLPTYMHPTTTTILTHLPLTPNGKINRNHLPHP
                     TTTTPATTEEPASQLEKRILVLVGKILDSRRISVTANFFDLGLDSVVMVKVHRELRDGL
                     GRDFALTDLFENPSIRHLAAHLGGADTTEDAVAATFARARDRRARRRPQTTTTTTDGAL
                     A"
     aSDomain        complement(53173..53361)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29745_PP-binding.2"
                     /evalue="5.70E-15"
                     /label="HUW46_RS29745_PP-binding.2"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1719"
                     /protein_start="1656"
                     /score="47.4"
                     /tool="antismash"
                     /translation="ILVLVGKILDSRRISVTANFFDLGLDSVVMVKVHRELRDGLGRDF
                     ALTDLFENPSIRHLAAHL"
     aSModule        complement(53173..56280)
                     /complete
                     /domains="nrpspksdomains_HUW46_RS29745_Heterocyclization.1"
                     /domains="nrpspksdomains_HUW46_RS29745_AMP-binding.1"
                     /domains="nrpspksdomains_HUW46_RS29745_PP-binding.2"
                     /locus_tags="HUW46_RS29745"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(53671..53736)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0016"
                     /evalue="7.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1553"
                     /protein_start="1531"
                     /score="37.1"
                     /tool="antismash"
                     /translation="FLGRTDTQVKINGHRIELGEIE"
     aSDomain        complement(53701..54879)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29745_AMP-binding.1"
                     /evalue="2.70E-95"
                     /label="HUW46_RS29745_AMP-binding.1"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1543"
                     /protein_start="1150"
                     /score="311.3"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="ADPSARAVFADGEWTTFGELYVRACRTARTLRSLGVGPGQVVAVS
                     MDKTAAQITAVVAVLLAGGVYVPIDPELPTARRHHMATHAGARLILTTEARETLDWPDN
                     TRVALLDTAPVDLAEATRDATPEQVSQLDDLAYIIYTSGSTGLPKGVAITHRAASNTCL
                     DINARFGVTSADRALALSSLSFDLSVWDVFGVLGAGGSLVLPATGRDPAHWHELITTHD
                     ITVWNSVPALMTMYTEHLPTGTPATSLRLVMLSGDWIPLALPDNLWATHPDIDLYSLGG
                     ATEAAIWSVYHPITALDPEWTSIPYGTPLANQQLHVLDTQLQPCPIHTTGDLYISGDGL
                     ATGYHNDPGKTHAAFLTHPTTGTRLYKTGDLARRHPDGTLEFLGRTDTQVKIN"
     CDS_motif       complement(53815..53904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0015"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1505"
                     /protein_start="1475"
                     /score="36.7"
                     /tool="antismash"
                     /translation="PIHTTGDLYISGDGLATGYHNDPGKTHAAF"
     CDS_motif       complement(54415..54474)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0014"
                     /evalue="9.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1305"
                     /protein_start="1285"
                     /score="30.5"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGLPKGVAITH"
     CDS_motif       complement(54670..54708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0013"
                     /evalue="8.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1220"
                     /protein_start="1207"
                     /score="12.8"
                     /tool="antismash"
                     /translation="AVLLAGGVYVPID"
     CDS_motif       complement(55120..55170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0012"
                     /evalue="1.70E-06"
                     /label="Cy7"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1070"
                     /protein_start="1053"
                     /score="20.9"
                     /tool="antismash"
                     /translation="ISQTPQVWVDNQTYEKD"
     CDS_motif       complement(55285..55332)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0011"
                     /evalue="4.50E-07"
                     /label="afterCy5"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="1015"
                     /protein_start="999"
                     /score="22.2"
                     /tool="antismash"
                     /translation="DMDHRRFSGIEVLREL"
     aSDomain        complement(55390..56280)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29745_Heterocyclization.
                     1"
                     /evalue="1.50E-101"
                     /label="HUW46_RS29745_Heterocyclization.1"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="980"
                     /protein_start="683"
                     /score="331.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DLLIADV"
                     /tool="antismash"
                     /translation="YEPFPLTGLQQAYVTGRDDVYELGGVATHYYREFDSETLDVDRFL
                     GSLEKLVQRHEMLHATVSADGTQRVLRDHAVPVTVDDLRHLDGTAAAERLDRTRAAMSH
                     HVMPLEDGPLFEVRISRLTKSKVRVHIGVDLLIADVRSIQIFYDDWELLYNGKELAPLT
                     GEVSFRDYLIATERDADDAEYRRARDYWMDRIDTMPGAPRLPVVERAKNAKSRFRRIES
                     QLDAGTWTRITNRAGKYGVTPSAVLLAAYAVVLRTWSGSERFLLNIPMFNRQPLHHRID
                     EVIGDFTTILPLAVDA"
     CDS_motif       complement(55393..55452)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0010"
                     /evalue="2.70E-06"
                     /label="Cy5"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="979"
                     /protein_start="959"
                     /score="19.7"
                     /tool="antismash"
                     /translation="HHRIDEVIGDFTTILPLAVD"
     CDS_motif       complement(55453..55491)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0009"
                     /evalue="1.10E-03"
                     /label="afterCy4"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="959"
                     /protein_start="946"
                     /score="11.7"
                     /tool="antismash"
                     /translation="FLLNIPMFNRQPL"
     CDS_motif       complement(55504..55563)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0008"
                     /evalue="2.70E-08"
                     /label="Cy4"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="942"
                     /protein_start="922"
                     /score="26.5"
                     /tool="antismash"
                     /translation="GVTPSAVLLAAYAVVLRTWS"
     CDS_motif       complement(55855..55899)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0007"
                     /evalue="1.20E-04"
                     /label="Cy3"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="825"
                     /protein_start="810"
                     /score="15.3"
                     /tool="antismash"
                     /translation="RVHIGVDLLIADVRS"
     CDS_motif       complement(56077..56130)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0006"
                     /evalue="1.90E-06"
                     /label="Cy2"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="751"
                     /protein_start="733"
                     /score="20.3"
                     /tool="antismash"
                     /translation="LVQRHEMLHATVSADGTQ"
     aSDomain        complement(56368..56550)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29745_PP-binding.1"
                     /evalue="4.20E-09"
                     /label="HUW46_RS29745_PP-binding.1"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="654"
                     /protein_start="593"
                     /score="28.6"
                     /tool="antismash"
                     /translation="VRRLLEDVLGGDAPEDVLASDATLAGLGLDSLRGMLVRHRLAQET
                     GVRLALDELLLASARE"
     aSModule        complement(56368..58194)
                     /complete
                     /domains="nrpspksdomains_HUW46_RS29745_CAL_domain.1"
                     /domains="nrpspksdomains_HUW46_RS29745_PP-binding.1"
                     /locus_tags="HUW46_RS29745"
                     /monomer_pairings="NH2 -> NH2"
                     /starter_module
                     /tool="antismash"
                     /type="cal"
     CDS_motif       complement(56740..56769)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0005"
                     /evalue="9.30E+00"
                     /label="Cy2"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="530"
                     /protein_start="520"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="LRAAVTANHR"
     aSDomain        complement(56887..58194)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29745_CAL_domain.1"
                     /evalue="3.10E-99"
                     /label="HUW46_RS29745_CAL_domain.1"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="481"
                     /protein_start="45"
                     /score="324.3"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="DLHIRALAVAEALRTASAPGARILVLTPSARDYVIAVCGCLYAGR
                     CAVPLGYAGTPVSSAMAAAVGRDAGAEAILTSTAVAAEAKRRWQSAGGDAIAWLAVDEL
                     VRPSAADQAPARCAPEDLAMLLYTSGSTGDPKGVLNSHASILAGIRKMVRMTGIPAGAT
                     VVNWVPVHHGIGLIGHLLLSQYLGGDCSVLRTEDVVARPASWLEAISAANSPVFGGGPN
                     FVYDRCTDFVTAEEFAGLDLDNWHSALVAGERIRKNTLERFTARFGARGFARDSMFSVY
                     GLTETTLLVSGRRAGDIGSLALDRAALEAHTARIVPESDDTAIDLVSCGDPGPATTIRV
                     VDPETRTEVAPGRVGEIWAQGPFTAPGYWRRPRETAAVFDASLANGEGPFVRTGDLGFR
                     HDGELFVCGRLKELLIIRGRNLYPQDIETTAAGVHPA"
     CDS_motif       complement(56914..56976)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0004"
                     /evalue="1.60E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="472"
                     /protein_start="451"
                     /score="11.3"
                     /tool="antismash"
                     /translation="CGRLKELLIIRGRNLYPQDIE"
     CDS_motif       complement(57058..57144)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0003"
                     /evalue="8.70E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="424"
                     /protein_start="395"
                     /score="27.7"
                     /tool="antismash"
                     /translation="PGRVGEIWAQGPFTAPGYWRRPRETAAVF"
     CDS_motif       complement(57769..57828)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0002"
                     /evalue="7.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="187"
                     /protein_start="167"
                     /score="24.7"
                     /tool="antismash"
                     /translation="AMLLYTSGSTGDPKGVLNSH"
     CDS_motif       complement(58045..58080)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29745_0001"
                     /evalue="6.90E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="HUW46_RS29745"
                     /protein_end="95"
                     /protein_start="83"
                     /score="4.1"
                     /tool="antismash"
                     /translation="GCLYAGRCAVPL"
     misc_feature    complement(58156..58158)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            58626..59639
                     /locus_tag="HUW46_RS29750"
                     /old_locus_tag="HUW46_05903"
     CDS             58626..59639
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01188.1"
                     /locus_tag="HUW46_RS29750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05903"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_215542088.1"
                     /transl_table=11
                     /translation="MTATSAAPVVTATERTPAIRAAGLKKRFGEKWAVDGVDLTVPPGQ
                     IYAFLGPNGAGKSTCVRMMCTLLAPTEGTVSVLGHDTVRNQLDVRLRVGVALQATALDD
                     KQTGLEQLRLQGRFYGLGKKTIGKRVGELTELIDLGDAVRDRVGTYSGGMRRRLDLAVA
                     LIHNPRVLFLDEPTTGMDPASRIKLWAEVNRLNRELGTTIFMTTQYLEEADQLAERVGI
                     INEGKVVAEGSPEELKRSIGKDLIVATTSDGTSAEIALRGLPVVQRVDVNGEEVTIAVE
                     DGPTAISPVALALAENAVTVRNLVLRRPTLDDVFLSITGQHMSEEDALADAGKVTQ"
     gene            59636..60460
                     /locus_tag="HUW46_RS29755"
                     /old_locus_tag="HUW46_05904"
     CDS             59636..60460
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="HUW46_RS29755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05904"
                     /product="ABC transporter permease"
                     /protein_id="WP_215542089.1"
                     /transl_table=11
                     /translation="MTATTEATTAVRAETEELVGRPAGFLRDLVSVSGRSLRQLVREPE
                     TLIPPMLISVFFFTVFVGALEKIGNLGGTADFRAFQFPVAIVIASTGTTRATSLVQDIN
                     NGYFDRLLIAPTNRLSLLLGLMVADLVTVVVLCIPTVVLGFVFGVGFASGVLGVLVFIA
                     IAALWGLAFAAIPYAIALRTGNATVVAQSSLLFFPFVFLTTTLMPLDRLSGWLAAVAHV
                     NPVTYLLAALRSLLTDGWNGPTLLLGVGVVLAVAVVTFSIALLALRGRVSRS"
     gene            complement(60711..61298)
                     /locus_tag="HUW46_RS29760"
                     /old_locus_tag="HUW46_05905"
     CDS             complement(60711..61298)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="HUW46_RS29760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05905"
                     /product="response regulator transcription factor"
                     /protein_id="WP_215542090.1"
                     /transl_table=11
                     /translation="MLKSTNSYSITEWKYLEDANRTAGAPGHRCPDVVVLGCNGLNTDT
                     VQLYAERARAAGSKVLLLLLIQNPELFDAVSSIPANGFLLLHQITPDSLDRALREVVSG
                     EIVIPSVLAGRMLTRLRTGSTAQRHGLASLTPREEQALRLLVDGLSNKQIAKQLRISQH
                     GAKRLVANVLAKLNCPNRTLAVAVALRDNIIA"
     misc_feature    complement(61263..61277)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    complement(61265..61281)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    complement(61267..61282)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.82"
                     /tool="antismash"
     misc_feature    61475..61490
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     gene            complement(61606..62217)
                     /locus_tag="HUW46_RS29765"
                     /old_locus_tag="HUW46_05906"
     CDS             complement(61606..62217)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF036525.4"
                     /locus_tag="HUW46_RS29765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05906"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_215542091.1"
                     /transl_table=11
                     /translation="MSQAWQSAVETHKARYREQIIDAAIELIADDGVTKTSMAKLAQHA
                     GVGRATLYKYFPDVESALLAHVGREIDVCEARLDEVIAEHEDPLEQLRACVRALLDYFA
                     SRQHRVGWASLDKADLSAKAMATLREEMTRLHKAIIATLRDGIAAGRMRKELDSQRHGK
                     LVFKMVASMQEDITVGALSADEAMDTIWLLLSHGVLHQGR"
     misc_feature    complement(62295..62315)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.67"
                     /tool="antismash"
     gene            complement(62413..63747)
                     /locus_tag="HUW46_RS29770"
                     /old_locus_tag="HUW46_05907"
     CDS             complement(62413..63747)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="HUW46_RS29770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05907"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_215542092.1"
                     /sec_met_domain="LANC_like (E-value: 3.6e-42, bitscore:
                     143.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVETGTWRGATAERAREFVTLLSDRFADPTAVSRTAAEVLAAEN
                     GGWVPTGLANGHPGLAVFYGQFAESGGRHAAAAHAHLLASMRAVGDHPALGLYLGPASI
                     AFAAQTCGARTGDYASLRSSLLTWAAGNQATRIEAASAPETGVAEGTYDVITGITGVGR
                     ILLDALSADEENSPAVESAVLATLRFLVRLSETRDAAGHRVPGWWTAPEQLPLAEERRY
                     YPIGAANTGMAHGIAGPIALLSLAAQRGVLVDGQLDAIGSLCGWLIGNASSDQDGPFWV
                     PRVPPGDRLPEDGVRPRDGWCYGVHGIAAALHRAGTVLDRGAWRELAVTAVRAASSHDA
                     LVTDPYLCHGHAGRLQVVHRLAVAEQDGELLALARRIAARLLDFVDFDAPFLVVAPVHD
                     GPGYQVCHRPGLLDGAAGVGCALNALLTGEPGDGNRNWDRMLLLS"
     gene            complement(63744..63917)
                     /locus_tag="HUW46_RS29775"
                     /old_locus_tag="HUW46_05908"
     CDS             complement(63744..63917)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05908"
                     /product="hypothetical protein"
                     /protein_id="WP_215542093.1"
                     /transl_table=11
                     /translation="MNTKELVAGYDIFTSVEELSAVTAVPSSAQTGTLQSVTTPSPLCP
                     SPCVTVTLILCA"
     misc_feature    63911..63925
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.41"
                     /tool="antismash"
     gene            complement(63923..64900)
                     /locus_tag="HUW46_RS29780"
                     /old_locus_tag="HUW46_05909"
     CDS             complement(63923..64900)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF037672.4"
                     /locus_tag="HUW46_RS29780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05909"
                     /product="T3SS effector HopA1 family protein"
                     /protein_id="WP_215542094.1"
                     /sec_met_domain="HopA1 (E-value: 1.6e-44, bitscore: 150.8,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGDALCPDLVATLPQVRVDPLCRKATVGEDEVTGANARELVRAL
                     GHQLYRNAHTGAIAATARGTDRDHALERRLAEAVPRTTTTITVPVLDVREDGTVVVERD
                     GLRVAAEPGSLRSTAPPRRGETVDLDVSTVRPAVSPGFFLTAQRHGTRAPGPVLRVYLH
                     LVELDAMTAVWRTVLHALHAKGASHLAKVLSGPEALPRRDAMVVYLDADSIDFVAHLPE
                     LLDDHPGLGTETSAFAKRVRPGVAIAWEPADPRPGMGALSFGQHRALALATGLVRHAAE
                     PGGGSRIGRVAEALREANIDPAAPARNLDSPDLPGLCASAPAER"
     gene            complement(64897..65973)
                     /gene="lxmK"
                     /locus_tag="HUW46_RS29785"
                     /old_locus_tag="HUW46_05910"
     CDS             complement(64897..65973)
                     /codon_start=1
                     /gene="lxmK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038156.1"
                     /locus_tag="HUW46_RS29785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05910"
                     /product="class V lanthionine synthetase subunit LxmK"
                     /protein_id="WP_215542095.1"
                     /sec_met_domain="APH (E-value: 3.5e-13, bitscore: 49.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVAVQQPPEHVDAVLRALGIGGFVDDGLPAPRGRNTSYAGTTE
                     SGQDVFVKVVASSSGAAAADRLGRAMAFQRYFEDGYFAGLHAPNCLGVDEATGVMVFEL
                     VRDARSGRDLAGDGEFGEDLAHRLGEAIGALHAAPLPPGTDSSYPPYPPGEALDALPAR
                     VFENSSAAALQAWALMQRDEVLLEAVRRLRDRDSSTVLEPAHCDLRLDQVLWHGGELSV
                     IDWEEFRLAEPARDLGALIGEWLHRAVTEIPAAGDPDLPDPALTHEQILAAGAAAIDEF
                     RPWVAACYAGYQAVRGPRDDRFAARCCAFAGWHLLDRMVAAAERLPALGAVERAGAGIG
                     RTILADPDRFTRALGLAA"
     cand_cluster    65121..85663
                     /candidate_cluster_number="6"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="6"
                     /tool="antismash"
     protocluster    65121..85663
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[75120:75663](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="6"
                     /tool="antismash"
     proto_core      75121..75663
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="6"
     gene            66186..66560
                     /locus_tag="HUW46_RS29790"
                     /old_locus_tag="HUW46_05911"
     CDS             66186..66560
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05911"
                     /product="hypothetical protein"
                     /protein_id="WP_215542096.1"
                     /transl_table=11
                     /translation="MRVLTTMAALSALLAIAACKPGTPDAGGGRTCSTSVPRPRITEQD
                     NGKTICMGRKAPLTVTLHGSAGDPWQAVSASGPVLTETGRPAVSGAVTTAAYQSNRAGS
                     GTVSAHRKSGRFEITVIVRD"
     gene            complement(66568..67272)
                     /locus_tag="HUW46_RS29795"
                     /old_locus_tag="HUW46_05912"
     CDS             complement(66568..67272)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 9.1e-18. Score:
                     56.7. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29795_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501448.1"
                     /locus_tag="HUW46_RS29795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05912"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_215542097.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-37, bitscore:
                     127.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1e-28, bitscore:
                     100.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTALVTGGSRGIGRAIVLRLAEDGADVVFSYHSDETAARDVVA
                     EVRGKGGRATAVRADVTDAAQIERLFEAVPELDVLVNNAGIGSAKVFGEVTEQWYDHVM
                     AVNAKGAFFVLQQAIPRLRQDGRVINISSSATAWPSLTDPVYAAGKAAVEQFTKVAARQ
                     LGPRRITVNTVSPGPVHGDAVPDEATAAIAALTPLGRMAEPADIADVVAMLAGRDGRWI
                     TGQNLIAAGGML"
     aSDomain        complement(66766..67263)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29795_PKS_KR.1"
                     /evalue="9.10E-18"
                     /label="HUW46_RS29795_PKS_KR.1"
                     /locus_tag="HUW46_RS29795"
                     /protein_end="169"
                     /protein_start="3"
                     /score="56.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGGSRGIGRAIVLRLAEDGADVVFSYHSDETAARDVVAEVR
                     GKGGRATAVRADVTDAAQIERLFEAVPELDVLVNNAGIGSAKVFGEVTEQWYDHVMAVN
                     AKGAFFVLQQAIPRLRQDGRVINISSSATAWPSLTDPVYAAGKAAVEQFTKVAARQLGP
                     RRI"
     CDS_motif       complement(67192..67257)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29795_0001"
                     /evalue="4.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="HUW46_RS29795"
                     /protein_end="27"
                     /protein_start="5"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAIVLRLAEDGA"
     gene            complement(67269..68609)
                     /locus_tag="HUW46_RS29800"
                     /old_locus_tag="HUW46_05913"
     CDS             complement(67269..68609)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017044.4"
                     /locus_tag="HUW46_RS29800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05913"
                     /product="pitrilysin family protein"
                     /protein_id="WP_215542098.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 3.7e-06, bitscore:
                     26.1, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.6e-14,
                     bitscore: 53.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGQLSDVDVPALLPRGALVLPESAEVTLPSGLTVLAVRQPSIPL
                     VEMRLRIPCAEADSATIALLADSLCSATSRTPTAELAKRLQRMGGSLSATVDADRLLFL
                     GSALAAHLGDLLDLLGEVLTAASYPEVETAQRAARFADALRVVKVQQGHRALEALNRRL
                     YGDHVYARPTPSPEDVLAVTPADLVALHAERVRAASACLVLAGDLDPQQALRTAERALS
                     GFAGGGEPVRHRPLPACRGGTPIGLLDAPGAVQSSVRLALPCPGPGAADFAELDLANLI
                     FGGIFSSRLAANLREDKGYTYSAKSTVVSPQAGSAVAVLADVATAVTAPAVLEIGYELG
                     RMACTPVRAAEVDQAREYLLGVRQLSMSTQSGLANLVSELAAQGLRLDWLGEHASRLVD
                     ADVPAVTEAAARYLNPPSAVVVVVGDAAEVAAPLAALMPVSRNGVEP"
     gene            complement(68606..69901)
                     /locus_tag="HUW46_RS29805"
                     /old_locus_tag="HUW46_05914"
     CDS             complement(68606..69901)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152685.1"
                     /locus_tag="HUW46_RS29805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05914"
                     /product="pitrilysin family protein"
                     /protein_id="WP_215542099.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9e-19, bitscore:
                     67.0, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1e-24, bitscore:
                     86.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEPLIGDRLERFTLPNGLRVVLAPSTAVPVVGIAVLYDVGIRSE
                     PVGRTGFAHLFEHLMFQGSEKVPKLAHARYVQGAGGSFNGSTHLDYTVYHETLPSTALE
                     RGLFLEADRMRGPRITERNLRNQVDVVSEEINTSVKNRPYGGFPWLHLPPLLFDGFANT
                     HDGYGSQVDLDSATVAEANAFFEQYYAPANAVLCVAGGIDVEETTALVARHFGTVPARP
                     VPVRPSFAEPALTGSRRGAHRDPLAPLAAFATGWRVPDPIGEFRSYLAHQLLADLLAGG
                     ESSRLVQRLVQADGTLADVSAGLGLMGDSLAVRDPGAFVVSGFLSPGGAADKAVRVVDE
                     EIERIAAEGLDDDEVLRLRTMAVSRLVRELDSVVGRAKLFGLFEQQRGDAALIAELPGL
                     LSSLTGDEIAAAAATVGEAHRAVVEILPGAAR"
     gene            complement(69936..70352)
                     /locus_tag="HUW46_RS29810"
                     /old_locus_tag="HUW46_05915"
     CDS             complement(69936..70352)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05915"
                     /product="hypothetical protein"
                     /protein_id="WP_215542100.1"
                     /transl_table=11
                     /translation="MRRLTALVATALLVLITAGTADAASKNWTTRYNGGSATGTAHYET
                     AGPHPYDGKVHADGTLTVADSGCYFATMEVMHFPGAWISHQNSATRCGPGSIPVNLTEV
                     VARGYWSGSVAVCQPAPNGGGWCDNWVDIYVDDK"
     misc_feature    70565..70579
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            70587..70841
                     /locus_tag="HUW46_RS29815"
                     /old_locus_tag="HUW46_05916"
     CDS             70587..70841
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05916"
                     /product="hypothetical protein"
                     /protein_id="WP_215542101.1"
                     /transl_table=11
                     /translation="MNRIESAAAESNLEVLEVSRDSATPVLTPVLITVTAFAVGTGVGA
                     VDCARHGCIDESGEGVRLNDVREMSVTELMQARRDATSV"
     gene            71145..71399
                     /locus_tag="HUW46_RS29820"
                     /old_locus_tag="HUW46_05917"
     CDS             71145..71399
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05917"
                     /product="hypothetical protein"
                     /protein_id="WP_215542102.1"
                     /transl_table=11
                     /translation="MNRIESAAAESNLEVLEVSRDSATPVLTPVLITVTAFATGVGVGA
                     VQCARHGCIDESGDGVRLNDIREMSVSELLQVRQDATSA"
     gene            71480..72304
                     /locus_tag="HUW46_RS29825"
                     /old_locus_tag="HUW46_05918"
     CDS             71480..72304
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05918"
                     /product="hypothetical protein"
                     /protein_id="WP_215542103.1"
                     /transl_table=11
                     /translation="MAQVDTPQVDKVIRQTEVISATGIALASLEYLMRPKHFEESGLLS
                     WQVGRTKYRWTSRKSADVLNPLFRPPGVQGVIGLRLTAASLLIAPGAKQSVRTAAVAYL
                     AVSNWLLHIRNSYGTDGTDHMNMLVYAALTLTKLFPGDTKAKEICTKFIAGQSVLSYLA
                     AGAAKAVSPYWRDGSAMSGVFRTHTYGERHVGELLKKFPSLAKAGGWGTIIGESIFPLV
                     LFGGKKTAVSLLATGAAFHAGNAAFMGLNRFLWAFCSTYPAVMHHSRSLRKR"
     gene            72325..74097
                     /locus_tag="HUW46_RS29830"
                     /old_locus_tag="HUW46_05919"
     CDS             72325..74097
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="HUW46_RS29830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05919"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_215542104.1"
                     /transl_table=11
                     /translation="MAAPVAGVYRRLFSLIRPYRAGLSVAVVLGLISSGLALAQPMVIG
                     ALVGKIVAGAPATVPALALGGLFLTDLVIGGVEVYLLGRAGASLVLDSRRRVVRRLLRA
                     PLGLHLRRQRGDLFTAAVADTDLLKTSLMQGLLNLVVSALMVVGSVVLMTVIDPVLTLS
                     TLAVLLLSGMATLIVAKRVRAAGVETRERVGDFASSLQRAIGAIRTVKLSRAEEREEAR
                     IGEFAGAAFHTGMRGVRLESAMAPIMNLGIQGSFAAVFTVGAFRLAGGSVDTAHFSSYL
                     LYLLYLIAPLISLFTAFAQIQLGFAAMLRVDAVADVPEETGGTSEPKPMTGTALSFEDV
                     TFGYQPGVPTVRGLTFDIPRRGFVAVVGPSGAGKSTIFTLVERLWDVDSGRILLAGQDI
                     RDLSLRDLRGRVGYVEQDAPVVDGTIRENLVFAKPDATEEQLADAVAKANLRRWIDGLE
                     HGLDTEVGESGTAISGGERQRIAIARMLLLRPEILLLDEATSQLDTEAEIALGTSIAAV
                     SADCAVLAIAHRMATVVAADRILVVDEGRLQAVGDHESLVATNELYQRLVRTQLGGTEQ
                     GNWAVETELAGRIR"
     gene            74094..75086
                     /locus_tag="HUW46_RS29835"
                     /old_locus_tag="HUW46_05920"
     CDS             74094..75086
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (64-173). E-value:
                     4.8e-19. Score: 60.9. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29835_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="HUW46_RS29835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05920"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_215542105.1"
                     /sec_met_domain="PF00561 (E-value: 3e-15, bitscore: 55.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.7e-14, bitscore:
                     53.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTTVKLCAGAGIAAALAPLAAGFTLQRRATRRDDEKYPGIGER
                     VDVGGYRLHVHTAGLDNEGPTVLFEAGMSCSLEVWAWVQDEIARDTPTVSYDRAGLGRS
                     DRGPRPRTAEDMRAELDQVLEAAGTKGPYVLVAHSFGGLLVRKFAHDHPDRVAGMVLVD
                     SSHPEQMVRSARQALGLPLMRSTIQNAVLLAAVGINRLSDRYIVSGVEHLPERVREAAC
                     ARMLAHRTWKTTLQELRGWLDTVNDEVRDTTLPADLPLAVVTADVPNRADPVHDELQDE
                     LAALSANSKRLVVPDSDHLGLVMKERFAKYVTEAVADVVRAARTGRPLD"
     aSDomain        74286..74612
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29835_Abhydrolase_1.1"
                     /evalue="4.80E-19"
                     /label="HUW46_RS29835_Abhydrolase_1.1"
                     /locus_tag="HUW46_RS29835"
                     /protein_end="173"
                     /protein_start="64"
                     /score="60.9"
                     /tool="antismash"
                     /translation="PTVLFEAGMSCSLEVWAWVQDEIARDTPTVSYDRAGLGRSDRGPR
                     PRTAEDMRAELDQVLEAAGTKGPYVLVAHSFGGLLVRKFAHDHPDRVAGMVLVDSSHPE
                     QMVRS"
     CDS_motif       74481..74525
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29835_0001"
                     /evalue="8.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="HUW46_RS29835"
                     /protein_end="144"
                     /protein_start="129"
                     /score="12.0"
                     /tool="antismash"
                     /translation="KGPYVLVAHSFGGLL"
     gene            75121..75663
                     /locus_tag="HUW46_RS29840"
                     /old_locus_tag="HUW46_05921"
     CDS             75121..75663
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05921"
                     /product="hypothetical protein"
                     /protein_id="WP_215542106.1"
                     /sec_met_domain="cypI (E-value: 5.3e-30, bitscore: 103.6,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSRRARVARIVMGGFLGSWFAATLLSQDPFRKFPGARRYDPTG
                     AAIPDWRFFAPRPGMHDYHLLVRDELPDGSVTDWREVLPVEQRAPRHFFWYANRRAEKV
                     VADSVVGIVGFTKEEGRKKEDIQLSVSYLTILNYMTYQEEHHNDAKRTQFLIAASAGYD
                     ESEEPLMLFLSNLHPLP"
     gene            75678..76346
                     /locus_tag="HUW46_RS29845"
                     /old_locus_tag="HUW46_05922"
     CDS             75678..76346
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="HUW46_RS29845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05922"
                     /product="response regulator transcription factor"
                     /protein_id="WP_215542107.1"
                     /transl_table=11
                     /translation="MTRLVLAGSFTVDPANLAKLLSVAPDIETVEVVGSVDRLCELAEA
                     GNPVSALVYADLSEPDIASAAQTLARLDDRHSLIVVVESATVAKVRSTLRAGARGIVLP
                     DSPVEELLTAVRAVSAGHLFVPAPFLASLGERLFTLARRAADAGARLTPREAEVLRVMA
                     FGHPNSEIAEQLFISEATARSHVLNILRKLCARNRTEAVAMAYRDGLLAAEDLLPTATE
                     "
     gene            76353..76751
                     /locus_tag="HUW46_RS29850"
                     /old_locus_tag="HUW46_05923"
     CDS             76353..76751
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010315745.1"
                     /locus_tag="HUW46_RS29850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05923"
                     /product="DCC1-like thiol-disulfide oxidoreductase family
                     protein"
                     /protein_id="WP_215542108.1"
                     /transl_table=11
                     /translation="MPDRRPEELPLLVFDGDCGFCTRAVRWLFAKAKPAAEAIRYQQLD
                     LAAYDTTAERAGHEVLWIPLDGPISGGADGLARLLRTAKTRRWRVAGRVLGAVPVRWSA
                     RPVYRAVARNRHRLPGGTEACAIRIVSS"
     gene            complement(76819..77148)
                     /locus_tag="HUW46_RS29855"
                     /old_locus_tag="HUW46_05924"
     CDS             complement(76819..77148)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020498222.1"
                     /locus_tag="HUW46_RS29855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05924"
                     /product="transcriptional regulator"
                     /protein_id="WP_215542109.1"
                     /transl_table=11
                     /translation="MTGGHPRRKLDDIIHSPVRLSVMAVLAVTDEVDFRYLKETVEVSD
                     SLLSKHIAVLQNADYVNVTKGVARNRPTTWFSLTETGSAAYREYVSTLNQIIGNGTAEE
                     KSDAS"
     gene            complement(77145..77576)
                     /locus_tag="HUW46_RS29860"
                     /old_locus_tag="HUW46_05925"
     CDS             complement(77145..77576)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05925"
                     /product="hypothetical protein"
                     /protein_id="WP_215542110.1"
                     /transl_table=11
                     /translation="MAVNEDGPLDHIAATSRISQLESKVGRTKKLYVTSVALLGVLTLG
                     FFAVVGGVPRASVKPYDSLLFLFPIVAAFVVAGIQKASTSGHRVLRIEQLLLTGYILSC
                     AAVIALDIFVLKQGTLAAALPGVVPAAICFAGAVVLGKR"
     gene            77784..78041
                     /locus_tag="HUW46_RS29865"
                     /old_locus_tag="HUW46_05926"
     CDS             77784..78041
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05926"
                     /product="hypothetical protein"
                     /protein_id="WP_215542111.1"
                     /transl_table=11
                     /translation="MNRIEFAVAKHVPDTASAHPLLEVTAEQMITCTPTIFSAFGIGYL
                     VGKAFGPSEESEPGAAAAFHDNIATMTGGELIQFRRDSLA"
     misc_feature    78157..78171
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.41"
                     /tool="antismash"
     misc_feature    78511..78527
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.28"
                     /tool="antismash"
     gene            78549..78803
                     /locus_tag="HUW46_RS29870"
                     /old_locus_tag="HUW46_05928"
     CDS             78549..78803
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05928"
                     /product="hypothetical protein"
                     /protein_id="WP_215542112.1"
                     /transl_table=11
                     /translation="MNRVELAATKQIPEATSAQPMLEVTPEQPITCTPTIFAAFGAGYL
                     VGKAFGPSEESEPGATAAFHDIATMTGGELIQFRRDSLA"
     misc_feature    78846..78860
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.04"
                     /tool="antismash"
     gene            78974..79414
                     /locus_tag="HUW46_RS29875"
                     /old_locus_tag="HUW46_05929"
     CDS             78974..79414
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05929"
                     /product="hypothetical protein"
                     /protein_id="WP_215542113.1"
                     /transl_table=11
                     /translation="MTALVVAACSAPAAPPAPAPPSSTAPPGTTTAAESPFCTDLRALQ
                     AGVLVYRADVLKAARSEQQLDVDGMRRRAGAIASLGQSVLAHAPQAISEQIHHVLDAIA
                     TSADRMAKRGARVRDVYDPLFTDAARPAFDTVDHYDCTATGG"
     gene            79723..80940
                     /locus_tag="HUW46_RS29880"
                     /old_locus_tag="HUW46_05930"
     CDS             79723..80940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104940.1"
                     /locus_tag="HUW46_RS29880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05930"
                     /product="DUF4041 domain-containing protein"
                     /protein_id="WP_254125019.1"
                     /transl_table=11
                     /translation="MEAELRNLRSAVDLAKEERAGLAASQQKLRAEADMWHQRVVETRD
                     VALLQEVGLYEYAHPLDDALAYKDALKELKERTKAAAKSDAVTCQVDWAVNGSVKEGQK
                     LGRDMAKLMLRAYNAEADNAVRVVKPHTRESVKNRLTTTRDTIGRLGKLMRIVISPDYH
                     RLRLREIDLTADYLMKVEVEREAARAERDRLREEAKVIKELERKRAKLEKERAHYVSLL
                     GKLESTGDGEALAKAQEQLASIDQAIAGVEERAANVRVGYVYVISNIGAFGPKMVKIGM
                     TRRQEPMDRVRELGDASVPFRFDVHALIFSKDAVALETALHQRLGHKRVNRVNQRREFF
                     YATPAEVKELLVELGDDHVVEYSDRSEALEWRASQPRGSGSAPLELAAVGAQEDADGDL
                     SDDGRE"
     misc_feature    79915..79917
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            80944..81525
                     /locus_tag="HUW46_RS29885"
                     /old_locus_tag="HUW46_05931"
     CDS             80944..81525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104939.1"
                     /locus_tag="HUW46_RS29885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05931"
                     /product="DUF2510 domain-containing protein"
                     /protein_id="WP_254125021.1"
                     /transl_table=11
                     /translation="MTQPPLSAQPTRPAAWLPDPLDDSLIRYWDGTRWTFRTADRPASA
                     PVAAEPGAPEPVEPALRPDIAQAVDRVRGLLVGSMKEVNLLAGHLRPEEHVLALTGAQG
                     EGQGVLACTNQRLLFLFVGIIRRQFLQVEWNQARAVIYNGGTKQFAVYTTRPTKRAVPA
                     MAVRVNNVKDAQVVANAAVEASAAPRLDII"
     gene            complement(81581..82771)
                     /locus_tag="HUW46_RS29890"
                     /old_locus_tag="HUW46_05932"
     CDS             complement(81581..82771)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS29890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_05932"
                     /product="hypothetical protein"
                     /protein_id="WP_215542115.1"
                     /transl_table=11
                     /translation="MEEAIFAELVRAAAGSRELDRLCERHAQRLLDNGTEPDFAISSAD
                     FVGDGALICADRYWRLRFLDHPTISTAGLCAEWIERNVATKFRPTITEKWALGYAFITR
                     DTVESETEVESATHEVVKARTPEIAHFAALYHAGKFRANFNCDELGEFLTSSPLVAAGK
                     LRTDPLFLALESFAAFGRHSITSEHAVQLLEEAWQSPDRTRAVIDICLNGLWWSRPFDR
                     QGELVHTYAREAIDKYPKDNIFYYRLAAGQRMCENYDEALRSIDTALELLPATGNRGSH
                     QQLQEQYLTERNSVRLEAQRTRWMAEQKALIADLKADNTALRETVQSAPVRMVEVVAVF
                     TAAIAFAVGSLQVTLNGTLPKGDRVVLIATLGAGLLLFALLIIGSTWFITRVRRRK"
     misc_feature    82799..82816
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(82910..83875)
                     /locus_tag="HUW46_RS29895"
                     /old_locus_tag="HUW46_05933"
     CDS             complement(82910..83875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646369.1"
                     /locus_tag="HUW46_RS29895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05933"
                     /product="2-dehydropantoate 2-reductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_215542116.1"
                     /transl_table=11
                     /translation="MKILMFGRGVIATIYGWALQRAGHDVEFYVRPGRAATYGDAVDLD
                     LLDTRRRPWGRRVVEKWPVRYREALEPDHDFDLIVLSVPHHRLDEATAFLSPRVGRATV
                     LVFGNLWTEPLAAIGALPPDRIAWGFPQAGGGFGANGVLRGMLLPSVIFGTLGQPPTDR
                     ERAVRQAFREAGLRIKEQPDLRGWLWVHFVSDAGLFSQGLRLGSLSELAGATGELRQAL
                     LTGRELLPVLKARGIDLRRHRGGVLLFRVPTWLMAPVLAWLTAHVTALRVSIEAHSHPD
                     AEEPREVCRDTLAEARRLGISVPRLEAAEPHFARARTGRA"
     misc_feature    83903..83917
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    83938..83953
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.35"
                     /tool="antismash"
     gene            83966..84541
                     /locus_tag="HUW46_RS29900"
                     /old_locus_tag="HUW46_05934"
     CDS             83966..84541
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646368.1"
                     /locus_tag="HUW46_RS29900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05934"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215542117.1"
                     /transl_table=11
                     /translation="MTTDKPLRADAQRKREALLAKAREVFDAGDFFDLRFDDFASLAGV
                     GTGTLYRHFPTREALAAAVYHGEVAALCDRARHLEATLPAAEALATFLRDMVDHIAAHQ
                     GLARTLATLMADRSGALTEGSQALEQAVADLVTAAARDGAVRDDVDAGAVMMALHGIGA
                     AHDRPGWRTEADDLVTLVLDGLRRPHSN"
     misc_feature    84695..84710
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    complement(84696..84709)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.44"
                     /tool="antismash"
     misc_feature    85095..85109
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.55"
                     /tool="antismash"
     gene            85095..85868
                     /locus_tag="HUW46_RS29905"
                     /old_locus_tag="HUW46_05935"
     CDS             85095..85868
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-239). E-value:
                     2.8e-22. Score: 71.4. Matches aSDomain:
                     nrpspksdomains_HUW46_RS29905_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495807.1"
                     /locus_tag="HUW46_RS29905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_05935"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_215542118.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-13, bitscore: 50.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-17, bitscore:
                     63.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQHIFHGDVRIAYEESGSGEPLVLLHGGESGRVQYDTFRPVLGD
                     GIRAIAYDQRDTGDSTNPAEPYRVDDLADDCAALIRGLGYERAHIFGASYGGAIALQVA
                     VNRPEVVRTLTAGTAIPRFSAAPASAQNLTHATEDRAAKMLDAVLSGKGQQEPKLLTEA
                     RRILLHRPAGADKRRMDAIREFDVLGRLGEITAPTLLIYGGDDPLGRVEYGQRIAEAVP
                     GARLEVLPGMRHGITLEAKHEVAALLRDFILTSSR"
     misc_feature    85118..85136
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.01"
                     /tool="antismash"
     aSDomain        85158..85811
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS29905_Abhydrolase_1.1"
                     /evalue="2.80E-22"
                     /label="HUW46_RS29905_Abhydrolase_1.1"
                     /locus_tag="HUW46_RS29905"
                     /protein_end="239"
                     /protein_start="21"
                     /score="71.4"
                     /tool="antismash"
                     /translation="PLVLLHGGESGRVQYDTFRPVLGDGIRAIAYDQRDTGDSTNPAEP
                     YRVDDLADDCAALIRGLGYERAHIFGASYGGAIALQVAVNRPEVVRTLTAGTAIPRFSA
                     APASAQNLTHATEDRAAKMLDAVLSGKGQQEPKLLTEARRILLHRPAGADKRRMDAIRE
                     FDVLGRLGEITAPTLLIYGGDDPLGRVEYGQRIAEAVPGARLEVLPGMRHGITLE"
     CDS_motif       85359..85409
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HUW46_RS29905_0001"
                     /evalue="1.90E-03"
                     /label="NRPS-te1"
                     /locus_tag="HUW46_RS29905"
                     /protein_end="105"
                     /protein_start="88"
                     /score="10.9"
                     /tool="antismash"
                     /translation="HIFGASYGGAIALQVAV"
ORIGIN
        1 cggggcctgc gcaggttcgc cccgcgcgct gtgagggccg agaaagtggc gtcagagtcc
       61 ccgaaggtgg ccttcgggga ccaagtgctc cccgctgcct cgggaggagc gagcggcatc
      121 agtgtggggt ggcgtcgcgg taggccacac ccgtcgcgtt cgcgtccttg cccgagtaga
      181 ggccggtggg cgcggtcgcg gtggacagcg tgaaccacgc gtagcgctcc acagaggaca
      241 aatcgccgag catggccgcc gagtccttgg cgaaggcggt ctgttcggcc tccgacgggt
      301 agcgcggagc cgggccggag aagtccgtca gcgcgtattc ggtgagccac accggtttgt
      361 ggtaccgatc ggccacggcc tggaggtagc ccttcagctg cccggtggcc gcgccggaga
      421 agtcgccgcc gtaccagtgc aacgggatga agtcgacgcg gtagccgcgt tcggccgcac
      481 cgctcatgaa gcggtccagc cagccgccag cctggtcgcc gccgaaggcc acggcagggg
      541 cgctcaaccg catcccggtc gcttcgagct gcggccacag gtcgagcgcc tgctcgacgg
      601 acatgttcgc ctgcccggcc atgtccggct cgttgaacgc gagcagcgtg ctgcccgacg
      661 ccttcgcctg cgcgagctgg tcggggttca ccgagccggg gccccagatc atcggcacga
      721 actcggcacc cggcggcgcc gcgatgccct tggggccgga gtcccaggtg tagaaccagc
      781 tcgcgccgac atcggcgagc gcgtcggtca cgccgtcgac gttcgccgcg ctgacgccct
      841 tcttcgccgc ttcggcggta ctggccgacg cgaccgacgg cacgagcaga agcgcggcca
      901 gtgccagtac ggcgaacctg cggatcgggt gcacgggatt cctccagact gtcaggcggg
      961 gcagtgcgat tcgccttcac cgtccactgt ggaaggttac ggtgaaaccg ctgcacgagg
     1021 tgcactggaa catggtctgg ttccccggct cggtgtcctg tttggaccac gcgtacgcgc
     1081 gagggcactt cgcctgcacg agatcgctgt agctggtctt cgcgtcccgg ttcgggttga
     1141 cgcagttcat cggcgaactg tccggccact tccgcagatc ctcggcgggg cacgagggca
     1201 gcacggtttc ggagcagccc gcctgaccgc acgaggccgg tgcgccgggt ggcggggtgg
     1261 cgttgtcggg gtcgatcgtg acgggaaggg agaaggcgtt gacgtagctc acgttgtacc
     1321 agggggcgag cttgtcggcg gggtcgaagt tgaactccgc gaggctcgcg ggctcctcgc
     1381 cggtggagca gtgatcggcg tcggggccgc aatcgccgac ggcgcaatgg aaatcacggc
     1441 cgctttcgcc ggtgcatccc tggcgcgcga agaactttcc tcgccagtgg ccgggcccgt
     1501 cggactccgg cacggtgatc gtggcggatt ccccgtcctt cagcgtcggc aggttcgcga
     1561 ggttcgccga gccgtcggcg ttgaccgcgc tgccgatcca cacggtgtcg ccggagtggt
     1621 tcacgaaggt caccgtgtga ttcgcggccg gggcggcctg cgacggtgac gggattccga
     1681 ctgcggcggc cagtgccagt accgcgaaca gccgccagct ccgagtgcgc atcagtgcct
     1741 cctcgtttcc tgccgatttt gacagttctt ccaccggaag tccctgcggt gcgaccgcag
     1801 gaaagcgtgc ggtcgcaccg cagcgcgttt tcccgcacaa cttggttagc gtttcgaaga
     1861 ctggcctgcg gcaagcgaat accgcgcgaa ggtggtgcac cacgcgggag aaaggtggct
     1921 gctcgtgttc aggaagacgt ggctcgtgtt cgtcggtgta gcggtggtcc tcggcggggt
     1981 cgtcccggcc gcggccgccg caccggaggt gccatcggga aaaacacagt gcgacggcga
     2041 cggaaccagc gggaaccggg tggaggcgct ctacgtgcgc ggcgacggcc agccggaccg
     2101 gtacgccgaa ctcgccgatc ggttccggac cttcgccgac cagatcgacg acgacttcgc
     2161 cgaggcgggc aagcggctcg gcggcggctc gcggcacgta cggtacgtca ccgacgcgga
     2221 ctgccgcgcg acgatcgcga acgtggcgat cccgcagtcc tcaatggaca ccgtcgacac
     2281 gatcaccgac gcgatcaagg cgaagggctt cgaccgcgcc gaccggaagt acctggtctg
     2341 gtacgacaag gacggctgcg ggctggcctt cggcaacggc ggcgacgacc gtcccggcgc
     2401 ggacaacccc tacaacgcgg ggccgcacta cgccacggtc ggcaccggct gctggtcgtg
     2461 gcaggccagc gggcacgaac tgctgcacac cctcggcgcc gtacagggca gcgcgccgca
     2521 cgcgacgaag aacgggcact gctgggacga cgaggacatc atgtgctacg acgacggcgg
     2581 catcccgaac ccgcccggtg gcctggtgaa ggtctgcgaa ggcgcgccgg aaaaccagat
     2641 cgactgcgac ggcgacgact acttcaacac gaacccgccg gagggcagct acctcaagac
     2701 gcactggaac gtggcgaaca gctcctacct gatcaccaag ggatgatcag cgcggcaggt
     2761 tccggtgggc ccgcgcgtgc aacgcgatcc cggccgagac ggacacgttg agcgactcag
     2821 cgagggggtt catcgggatc gacaccgcgt cggcggagat gcccgcgaac tcgcccgacg
     2881 caccggtctt ctcgctgccg aacgcgagca ccagccgctc ctcggccgtg ccgagatcgg
     2941 cgacggtgag cgcgccgccg gtgtcgaaga gcaccagccg cgcaccgctt tcccggatgt
     3001 gggcgagcgc ctcttcccgc gaggccagca cgatcggcag cgagaacacg tacccgcggc
     3061 tcgccctgat caggcgccgg tccgcgatgg tggtgaggtc gctgtcgacg agcacgatgc
     3121 ccgcggcccc gagcgcgaac gaggtccgca cgatggcgcc gatgttgccg acgatcttca
     3181 cgccgtcgag gaggatgagg tcgccggtgg tgccgttcaa atcggcgagc ttccgaggcc
     3241 gcgggacctt ggcgatcccg aacgccttcg gcttcttctc ggtcttgaag acctggttgg
     3301 cgatcgtggt ggcgagcagc cggaccccga tgccgcgctc ggcgcacgcg gcgagcagtt
     3361 cttccggcag cgaggtcgtt tcgagcccgt agacctcggt gaactccagc ccggcccgga
     3421 tcgcctgcag cagcggctcg acgtcctcga tcagcgccgt cttgacgacg gaccgggagt
     3481 gcttggtgac atcgatgatc cgctgcacgg cgggatcgga tcgctcggtg atgagatcag
     3541 ggctggtcac cgcgaaacgg taacacgcgc gcccgcccgt gccgcgaagt tcctttgtgg
     3601 acggtggtgt cgcggccgat gcccgcgaca ccaccgtttc cggctcagtc cgcgggtttg
     3661 gtgaggaacg cggggagcgt gcggtggccg ttggagatga acgaggccac cgtctccagc
     3721 tcctcggccg gcaccgcgag ggtgagatcg gggaacgcgg tgaacagcgc gggcagcgcg
     3781 atctcggcct ccagcctggc cagcggggcg ccgaggcagt agtgcacgcc gtggccgaac
     3841 gccaggctgc ccttgtcttc gcgggtgagg tcgaaccggt cggcgtcctc gccgtggtgc
     3901 gcgctgtcgc gcccggccgc ggcgtaggag gccaggatcg gctcgcctgc ctggatcgtc
     3961 agcccgtcga tttcgatgtc ctcgacggcg tagcgcagcg gcaggtgggc cacgggggct
     4021 tgccagcgca gggtttcgtc gatcacgtcc gtccacgtgc gctcgccgtc gaggacgagg
     4081 cggagctgct cggggtgggt gagcagcgcg gtgatggcgt ggtcgaggag gttgacggtg
     4141 gtttcgtgcc cggccgagat caccaggatc agcgtgtcga ccatctcggc ttcttccagc
     4201 cgcgagttgt cctcgtcgcg ggcgctgatg agcgcgctgg ccaggtcgtc gccgggcttt
     4261 tcccgcttgg cggcgacgag ttcgctcagg atgcggtaca tgtcctgaac gttcgccgcg
     4321 gcttcttcgg gggtcgcggt ggtgttgaag acgccgtcca cggcgcgctt gagcccgggg
     4381 cgcgcgtcgt cgggaatgcc gaacagctgg cagatgacct cgatcggcaa cgggtaggcg
     4441 aaggtttccc gcaggtccgc ggtgttcggc ccggcggcga gcgcggagat cagctcggcc
     4501 gtgatctgtt ccacctgcgg ccgcaggttc tgcgtccggc gcggggtgaa cgccttggac
     4561 accagcgcgc gcagccgccg gtggtcgccg ccgtaggcgg tgaacatgtt cttcaccgaa
     4621 acccagaggt gcaacggcca gtccgcgggg atctcaccgc gggtgtaggc gggccagtgc
     4681 tggttcgggt ccttggagac gcggggatcg ctcagcagcc gcttgagcag atccgggttg
     4741 gtcaccgacc acgccaccac ctggccaggg agctccacca gggtcgcttg cccccgttcg
     4801 cggagccggg cgccttctcc gtggatgtca cgtccagtgg ggtcgaggac gactgggctg
     4861 gcggtgcggt ccatgcgcgt tctcctgact gctgggtggg cggtgcggac ggaggaagtg
     4921 gatcgggtgg cgcggccacg gtgacggggg tgaactggac gggaagcgcg gaaagcgcgc
     4981 ggtggaaggg accctgccgc cacacgaggt cctcgaccgg cacggcgagc cggacgtcgg
     5041 gcagcgcgtc gagcagggtt tcgatggcgg cggaggcgat gatcctggcg ggcagctgcg
     5101 ccgggcaggt gtgcatcccg gcgccccacg cgaggtgcgc gcggttgccc gcgcggtgct
     5161 cgatgttgag cgcgggatcg gtgttggccg cggcgaagct gatcaccagc ggctggtcgg
     5221 ctggcacgcg gacgccgaag aggtcgagat cggtccacgg gtagctggcc gagtagttgg
     5281 ccatcggcgg gtcggtccac aggatctcgt cgagcgcgtc ctcgacgggc atgctgccgc
     5341 ccgcgaggtc accggcgaac cgctcgtcgg agagcagcag ccgcaacccg ttggcgatga
     5401 ggttctgctg cggttcggtg cccgcgccca tcatcaggat catctggtgc agcagctctt
     5461 cgtcggtgag ccgggccggg tgggccatca tccaggacgg caggtcgggg ccgggctggc
     5521 gccgcttgag cgcgatcagc tcgcccatgc actggccgag gttcgcgttc gcctgctccg
     5581 ggtcgtccat gtcgaagatg ccgcgcatgc tttcgagcag gcggtccccg agctcgggcg
     5641 ggcagccgaa gaggtggccg aacacgccga gcgcggtcga agtagcgtac tcgcggagca
     5701 gatcggccga cccgcgctgg gaaaaccggc cgatgtgccc gcgcgcggtc tgctcgacgt
     5761 agccgcggag ccggtgcggg tcgaccctgc cgaggctgct ggtcaccgcg ccgcgcagcc
     5821 tcgcgtgcac cgcgccgtcg gtgaataggc agttgggccg gtagcccatc atcggcagca
     5881 ccgggttgtc cggcggcatc cgccgttccc agcgccgcgg gtcgcggggg aacgtgctcg
     5941 gctcgcgcag cacttccagc gcggcctcgt agccgatgac gaggtgggcg tgcgtgcccg
     6001 gagccagttc gaccggcgcg accgacccgt gttcggcccg catgcgggcg taggtcccgg
     6061 cggggtccgc ggcgaactcc gggccgtgca gccgggtggg ggcgtgcgcg gggcagcccg
     6121 gcgggggcac cgggccgtcg ggcgtcgcgg gagcttcgga agctgaggtc acaggtgctc
     6181 ctggcgagtg gtgaagaggt ggtcgacgag tgcgatcagt gcgttggccg aggacgcgcg
     6241 gtcgcgcgcg tcgcagacca cgagccgggt ctgcggcagc aggtcgagtg cttcgcgtag
     6301 ttcggcttcg gggaagcgcg gcgagccgtc gaactggttg atggccaccg cgtagggcat
     6361 gccgagttct tcgagcaggt ccatgacttc gaaggactgc tcgaggcggc gggggtcggc
     6421 gaggacgagc gcgccgagcg cgccgtgcgc gaggtccttc cacatctgcg tgaaccgctg
     6481 ctgacccggc gcgccgaaca ggtacagcac cagttcgggg ttgagcgtca gcctgccgaa
     6541 gtccatcgcg accgtggtgg tctgcttgtc cggcaccccg gcgagatcgt cgacgaaggc
     6601 acccgcctgc gtcatcgtct cctcggtgcg cagcggcctg atctccgaca gcgtgccgac
     6661 gaacgtcgtc ttgcccaccg cgaacgggcc tgccacgagg atcttcaccg acgtgcgcac
     6721 gctcgcgggc acgtagtcgg cgtcaggtga gagcacggag gccatcgagc accttctgca
     6781 gtagctggag atcggcgtgg tcggcggatc cgaccgtggc gtgcgcgacg atgtggccgg
     6841 tgtccacgag atcggacagc agcaccttcg tcacgctcgc gggcagcccg aggtgggcgg
     6901 cgatctcggc gaccgcgagc gccccgcccc ggcagagctc ggtcatccgg cgcttttccg
     6961 ggctcagccc ggccacgggc gtcttggtcg cgaccaccac ggtggcgagg tcgaacgtgt
     7021 tgcgggtcgg gtgcgcgcgc ccgccggtca ccacgtgcgg ccgcaccagt gcgcgctccc
     7081 gccgcggttc ggtcatgccg gactgccgta accctgcggc gcgaaccggg ccggtgcggt
     7141 gagctcctgc ccgaggcgct ggaccagttg ctgcaaccgc gtcgacacgc cttccatgtc
     7201 gacgcggttg gtggccgaca cggcgaggta ggcgccgggg cccgcggcga cgaggaagac
     7261 gtacccgccg gtgaactcgg tcagcgtctg ccgccactgc tcggcggttt ccccgcagaa
     7321 ctcggccgtc gtgcgggcga gcgactgcaa ccccgacatc ccggccgcga tccgttcggc
     7381 gtcgtcgcgg ctgatgcgct gggaatgggc gatcagcaac ccgtcggcgg agagcagcac
     7441 cgcgtagagc gtctcgggca tctgcagcgc gtcgtcgagc atccacccga gcttgttgga
     7501 cggatcggtc actgactgtc cctttcggaa tctgcgggag cgggggcggt ttcgcggccg
     7561 gcacgggtgc cgcgctgcca cgcggcgagg gtggccgggg tccgcgcggc cacgggctcc
     7621 ggtagtgctg gttgcggggc gggttcgacg gcgggcgcgc gccgtcggcg ccgtggcagc
     7681 ccgttctcgg tccggccgag gtcttcggca gggctgggcg cgggtgcttc ggcttcggca
     7741 ggtgcctgct ccggcaccgg gtcccggttt tcgggttcca gtacccgcga caccggcatg
     7801 gtgtgcacgc tcggcgcgtt ctccctggtg agcagttcgc tgggcaggaa caccaccgcg
     7861 cggacgccgc cgtagggcga gcgggtgtcc accgagaccg aaaagccgta gcgggcggcc
     7921 aggatgccga tgaccgcgaa cccgatccgc ggcgggtcgc cgagcccggc gatgtcctgc
     7981 gtgccccgct gggcgagcag ccaggtcgcg cgctgcaccg cctccacggt catgccgacc
     8041 ccggcgtcgt cgatgacgat ggccagcccg ttgtgcgcct gctggaagtt gacctcgacc
     8101 ttcgagccgg gctgggaatg ccgcgcgccg ttgtcgagca gttcggcgac cgcgagcacc
     8161 accggctcca ccgcgcggct caccaccgcg gtctccgagg tggccgggat cgccacccgg
     8221 gggaagtcgc ggatccgcga ggtcgcgccg cgcgccacgt cggtcagcgt ggacgccgag
     8281 cgctgctggc cgggccacga cccgcacagc accgcggtgg cctgcgcgcg gcgcgccagc
     8341 tgggagttcg cgtggtcgat cttcagcaga tcggcgagca ccgcgggatc gtcgtggcgc
     8401 tgctccgcct ccgagatcgc gacctgctgc tcgttggcca ggttctggac cgagcgcatc
     8461 atcgccttca gtgtggacgc ggccgcctgc gcggcgccgg agcgcgcctg ccgcacgtag
     8521 tcggcgacca tcgccagcac gacgccgtgc gggtcaccgt tgccctgcgt cagcggccct
     8581 ggcacggaca ccgcggggtc ggcgatcgac tcgatcagcg acggcagcct cgtccgcgtc
     8641 aggtgctcct gttcggcttg ccgcgcgcgc agttcgtggt gcagcgcgtc gctcatcgcg
     8701 cgcgcccgcg tggtgatgcc gcgctggcgg accagcagga ccaccagcag caccacgacg
     8761 gcgagcagga cggagacggc gacgatcaag agcggttgat ccataaatcc tcatggtcga
     8821 aaatgcggcg aaccgcccgc gggcgcgaaa atcccgcgag cgcgctctgt tccaggcccc
     8881 cagttccctt cgaagccgag gtcaggcgcg cgccggaaac acgggtggtg ggagggggac
     8941 gacacctcgt gccgggtggg gcgcggtgga cgccttcgtc ggggggttca gtcgggtcac
     9001 cggcccgatg ataacggtgc ggacccagat cttgtccagg ccgagggagg aacggccaag
     9061 atcctttcgg cgtacggctt acttcccccg gatggcgcag tggcacgccg ggtggcgact
     9121 ccggtgcgtg acccgctgtc cgcggcggcg gtatccggcc gacttgtgtc cattgtggac
     9181 tgatgggatg ggtgtttcgt cgtgcgtttc cgggcgcacg agagcgcccg cctcgttgcc
     9241 ggttattgaa gaacgagaat cggcgcccgc tggtgtgtcc cctggtcgcg cgggtgcgcg
     9301 gaattgtcac cggtcgtagt tcgcggcaca cgatcgagga gtcgccgtcc tgcccgttca
     9361 gcggattgcc gttttttcgc gcggctctct aagctgattc ggcggacgaa ttcaccgcga
     9421 tcagaatggc ctggaccaat tgcgttccgg ggtttccggc gccaattgcc tgctggtcga
     9481 aaaaatcccg gagaggggag gggtgtggct gatgcgtgcg cgggatccgc ccgtggttgt
     9541 cgttggcgcg cggtcagatt ttgggcatgg caagggaaat cgtgtgaccg ccgggggaag
     9601 ggtggtcttt tccgccgacg tggtccgcga ttattccgtc gaattgggca tggtgatcaa
     9661 tccgggtgga cgaggttggc ccggccccgt ctccggtgcc gggcacctgc cgccaagtca
     9721 tttccgtgaa cctttttcac aagagaaacc agggagtagg catgaccgag aatttgatgg
     9781 aatccgtcgc cccgcagctt tcgccgccgg tgacgaggca gccggtcggc accgccgccg
     9841 agacggccga cggcgccgag ctgtcgatcc tcaccatcgg cccggtgacc atcagcttcg
     9901 ccgcggacga cgacgagtaa ccacgccgtc gaagtgccgg gccgcgcggc ccggcacttc
     9961 cccgcccgag gcccgaaagg gccgggagaa ccgcggaagg gtgagcgaag tgtgcgaggt
    10021 gcccggtatt ccggggctgg ccgagttgtg gcgccggacc ctcggcgacg aggacgtgtg
    10081 cgtggcggtg gtcgacgggc cggtcgacct cggccatccg gccttcgacg gggcggcgct
    10141 gacccgcctg gccgggatct ggccggaaga agggctcgac agcgacaagg cggtgcacgg
    10201 cacgcacgtg gccagcgtgc tcttcgggca gcacggcggg ccggtcaccg gggtcgcgcc
    10261 ccgctgtcgc ggcctgtccg ttcccgcgtt ttcccagcgc aagggccgga cctcgcagct
    10321 cgaactcgcc cgcggtgtcg agctggcggt cgaggcgggc gcacacgtgg tcaacatcag
    10381 cggcgggcag ctttccccat cgggcgaggc ggaccggacg ctggccgacg cggtgcggta
    10441 ctgcaccgaa cgcggcgtgc tggtggtggc ggccgcgggc aacgacggct gcttctgcgc
    10501 gcatgtcccc gccgcgttgc ccggcgtcct cgcggtcggc gcgctcgacg accgcggggt
    10561 cccgatggcg atgagcaact ggggcgccga gtaccggagc cacggcatcg tcgcgccggg
    10621 agagcacatc ctcggcgcga gaccgggcgg ccggacggac cgggcgaccg gcaccagcct
    10681 cgccgcgccg atcgtggccg gggtggccgc gctgctgctg agcctgcaac accgggcggg
    10741 cctccgcccg gatcccctcg ccgtcggcac cgcgctgctg gacagcgccg acccgtgcga
    10801 ccccagcggt tcggcggcgt gcgaacgatt cctgaccggg aagttgaaca tagaaagagc
    10861 ggtagagact gtgacgagct cgatgagtgt gacgccccca gaacccgccg cggcggacgt
    10921 ggcaggcggc gaaccccgcc aggagcccgc cgcgccggag ctcctcgttc ccagcgcttc
    10981 gccggaaccg atcgtcatcc ccgagcccgc gaaggaatcg tgcggctgcg gatgcgacgg
    11041 gaccgcgccg gactcgtgcc ggaagcccgc ggtggtgatg tccgcggaac cggatcgttc
    11101 gcccgcggag cacccggtgt acgcgatcgg cgtgctgggc tacgacttcg ggaccgaggc
    11161 gaggcgcgac tcgttcaagc agctgatggc gcccgtcgcc gccgacggga ccgtggtgcc
    11221 cgcgaacccc tacgacgcgc ggcagatggt ggaccacctt ctcgcgcacc cgtcggaggc
    11281 ccgcgcgctg atctggaccc tgaacctgga gctgaccccg atctacgcga tcgaaccggt
    11341 cggcccgtac gcggcggagg tgtacgaact gctggcccgg ctgctcagcg ggcaggtggc
    11401 ggcgccgacg agcgacgact tcctggagcg cgtcgccgtg ccggggcggt acagcggccg
    11461 gaccgtgcgg ctgttctccg ggcagtcggt cccggtgatc gagctggaac agcgccgagg
    11521 gctctacggc tgggaggtca accggctcac cgaatccgcg gtcgacgccg ccgaagccgt
    11581 gccgggcgag agcgacgacg aggcgacgaa gcaggcgctg cggcagttcc tcacccgggt
    11641 ctactacgac ctgcgcaacc tcggctcgac ctcgcgcgac cgggcactga acttcgccgc
    11701 caccaacgcc ttccaggcgg cgcacacctt cgccaccgcg ctggccgaga agatggcgct
    11761 cgacacgatc accgtggaga agagcccgtt ctgccgccag gacagcgact gctgggacgt
    11821 caagctgcgg ttcttcgacc cggagaacag ccgccgcgcg aagcgggcgt tccggttcac
    11881 catcgacgtc agcgatctcc tgccggtcac cctcggcgac gtccgcgaat gggccgagac
    11941 gtgaccgcgc ggccgggaat cgcgcccccg caggtggcgc cggtccggcg cccggaactg
    12001 gtggagccgc accgctgcgt cgacgtcgtg cacggcacac ccgacgaact gatcgcgatg
    12061 cgcctgcgcc tcatgcacgg agccaacttc aacgaccccc aacgctggct ggacccgacc
    12121 taccagcgaa tgcggtcctc gttcccgcga aacacttgac agtggtcggt ttgcgtggcg
    12181 gtgcgggtgg cggtgcaagt tgcttgcccg ctcaagcggc tccgccgctt accaaagcac
    12241 aagcaattcc ccaggagtga agcgtcatgc cgaatccgaa gacgccgagg cgtcgtccgc
    12301 ccgcggcgcg gcggcgcgtc gaagcgccga gcgaacccgc cgtgagcacc gaaccggaac
    12361 aacccgccgg ggagcaggtg agcatcgagg aggtggaagc ggccgtggcg ctggcggacc
    12421 ggctcgaccg gccggtccgc atcccgcccg agcgcaggct ggacaccggc ctcgcggact
    12481 acgccatgtg gtttcgcatg ttctcggcag cgccgtccgc gccgccgccg tcgggcggcg
    12541 acaccagggc cgggcggatc tgggcctgac gccgtggccg agatcgccgc catccccggc
    12601 gtcggagagc tctgggcgca gaccctcggc gacccggccg tcaccatcgg gctcgtcgag
    12661 gggccgcccg agctgtccca tccgtgcttc gacggcgccg acctcaccgt gctggaaccg
    12721 cactggctgc cgcgcgtgcc ggtggtggac gggcttcccg agcacgccac cttcgtcgcg
    12781 agtgtccttt tcggacagcc gggtggcccg gtgcggggca tggcgccgcg gtgccggggg
    12841 ctgctcgtcc ccgcgctgcg ggacgagccg acactcctgg acccggtcaa cgccgtccgc
    12901 gcgatcgaaa ccctcgtcga agccggggcg gacatcgtgc acttcgccgc gtcccacccc
    12961 accggatccg gtgacgcgga cccgttgctc gccggtgccg tgcgacgggc gtacgaagcg
    13021 ggcgtgctcg tggtggcccc ggcgggcaac gactacggcg ggaactacgt cgcgcccgcg
    13081 gtgctgccgg aggcgctcgc cgtgggcgcg ctcgacgacg acggcgtgat gttccggttc
    13141 agcaactggg gcgaacgcta tagcgggcac gggatcgccg cgcctggcgg cgatctcacc
    13201 gcggccgcgc ccggtggcgg cacgtccgtc cacaaaggaa ccagcgtcgc cgcgccgatc
    13261 gtcaccggtg tcgccgcgct gctggcgagc cttcgccagc ggcgcgggct gccacccgat
    13321 ccgctcgccg tccgcgacgc gctgctcgcc agcgcgcgtt cgtgcggcgg ggcggacagc
    13381 cacggcgagc ccgctcgctg cttggcgggc aagctcgacg tgcccgccgc cacccggctc
    13441 gcgctcgccg gtgcgcggcc cgaagtggtc ctgtcggcgc ggcggcggaa cccggtgtac
    13501 gcgatcggga cactcggcta cgacttcaag accgaagccc gccgggattc cttccagcag
    13561 ctgatggcac cggcgaaccc ttacgacgca aggaagatga ccgagcacct cgccgcgcac
    13621 ccgaccgagg cgaaggcgct gacctggacg ctgcaccagg aactgacccc gatctacgcg
    13681 atcgagccga ccggaccgca cgcggccgaa gggtacgccg tgctggcccg cctgctgcgg
    13741 gggcagctcg aagccccgtc cagcgacggt ttcgtcgagc gggtcgtgct tcccggcgcg
    13801 cacgacgggc ggacggcgcg gctgttttcc gggcagtccg tgccggtgct cgaactcgac
    13861 cggctcagcg gcgtgcacgg ctgggaggtc aaccggctcg ccgcggcggt gctgccaggc
    13921 gggtcccgcg tggcgctgcg ccagttcctc gaccgcgtcc accacgacct gcgcaacgcc
    13981 ggggcaacct cggcggaccg ggcgctgaac ttcgccgctg ccaacgcttt ccaagccgcg
    14041 cggatcttcg acgcggcgct ggccgccggg ctcgccttcg acggtgtcac cgtcacgccg
    14101 agcccgttcg gccggccggg cggcgactgc tgggacgtga aactgcggtt cttcgacccg
    14161 gagaacgacc gccgcgcgag gcgggcgttc cggttcaccg tcgacgtcag cgacacgctg
    14221 cccgtcgcac tcggcgaggt ccgcgaatgg gccgagccgt gaccaccacc tccgagagga
    14281 agccatgtca gaaacccctt cccaccccgg cgtcgtcgag gtcccgtgga acctcaccgt
    14341 gccggaggcg gacatccacc tcgtcggcta cggcatgcgg atgcccaacg acctgacgct
    14401 ggaagcactc gcggtgctca agcgctgcaa gcggatcttc ggcatcccgc cgctgcacgc
    14461 gcccgagttc ggcatcccgg agatggaaaa cctgtacctg cactacggtc cggagaagaa
    14521 ccggcgccag acctaccggg aatggctgga cctggtgctc gacgccgccg ccaccgacgc
    14581 gccggtcgcg ctcgccaccg ggggcagttc catggtcggc gcgctcgtgc cgcaccgcat
    14641 cctcgaggag gccccgcgcc gcgggctcac cgtgcacgtc accaacgcgg tgtcctgttt
    14701 cgacggtatc tgggcggatc tcaacatcga gccgttcttc gggttttccg tgtgggaggc
    14761 caccgcgttc gtcaagctcg gcatcgcgcc ggacaccagc gccgcgctga tgctcccgca
    14821 ggcgccgatc ttcgacgtca gcaccggccc ggacgtcggc accaacacca tgacgaccag
    14881 ttcggcggtg tccgcccttc gcgaccacct gctccggtac taccccggcg ggcaccaggt
    14941 ccgcttcgtc cacaccggat ccggcacggg ggcgcgggcc atgacggcgg ccatcgagac
    15001 gctgccgctg gccgaactcg accaccccgg ccgcaacctg ctgagcaccc tggtcgttcc
    15061 gcggctcgaa ccgagcgctc aactggactt cgcgcgccga gaggaagcgg cggcgaagag
    15121 ttaggggccg gtgccggggc ggcggacccg ccccggcacc gaactgtcag cccggatggc
    15181 gggtcctgag gtagtcctcg atggcctcgg ccgccgcggg cgccccgccg tcttcgccga
    15241 gggaagcgcc gatcgcttgc gcggcttcgc gcggagaaga accggacagg gcgttttcga
    15301 cggcggctcg cagctccgcg accgggaccg gccgcttcga caggttgtgc cgcagcacgg
    15361 tcgcggcgcc acggcccgcc acggcctcgc cgatcacgag ctgttcgacc tgctggggca
    15421 ccacgaccag cggcaccccg caggcgagtc cttccagcgc gctgttcatc ccgccgtgcg
    15481 tgacgaacgc ggcggcgcgg cgcaacactt ccagctgggg caccgaagcg cggatcagcg
    15541 tgttcgccgg gggctttccc agccgtgccg ggtcggtgtg cgagccggcc acgagcagta
    15601 tccgcgcggg cagcccgccc aaggcctcga agcaggcgcg gaagaacgcg tcgcttccgg
    15661 cgtgcaaggt gcccagcgac accaggacga ccggttcggg accgtcggtg aaggcggcga
    15721 gttcgtcgtc gagcggggcg tcttcgcgcg gcgggcggat cgtgggcccg acgaagtggc
    15781 agccgtcgtc tatgcgcgga tcgggcgact gcatccagcg cggcaccggg aagacggtca
    15841 cgtcgccgcg catcggcagg cccggcgcgg gcgggtaggc gtccttcccg aattggcgca
    15901 ccacgcggcg cttcgccgag cgcgccgcgg gcacgccggg gatggcctcg ccgaggaagt
    15961 ggagccattc ccgcgcgttc aggcgtgcca tggccttgcc gccgatcagc atggtcgtca
    16021 tcagcgagat catcggcagg ccgaggcgtg ccgcggccat ccggccccag atcgcgttgg
    16081 agtcgaacgc gatcgcgtcg ggacgccggg tgtccaaatc ggacagcagc aggggcagca
    16141 gcgcttcggt cgccgtcagc accctggcca ccaccctgac ggggccaccg ttacgggtgg
    16201 cctcggcgat gtcggcgggg ccgagcgtgc ccgcggggta ggtgcggaat tcgcagcccg
    16261 cctcctcgac ccgcgcgcgg aagtcgtcgc tggtgtagta ggtgacctcg aagccgcggc
    16321 gcgccagttc gcgcacgatc ggcaggctcg ggttgaaatg gcccgcggcg ggcatacccg
    16381 ccacgacgat ccgcttcgcg tcagtcatcg tgctgtgctc cttgccggta accggcttgc
    16441 ctgaggacgt cgatgaagta cgccctgatc gcgtcctcac cgctggtgtc ggggtggacg
    16501 ctcacgtaga gcagcgccgc gccgctgaga atctgttgca ggacaacggg atctacctgc
    16561 gacgggaact gcccggcgcg ccgcgcccgg tcgagggtgg cgcgcaccgc ctccgctccg
    16621 ccgcggccgc gggtctccgc gtaggtccgg agcagctcgg ggtagtcgtc gaccgtggcg
    16681 tacagccgcc gcatcagctt gcggtcgcgg gggccgccga gctgcacggc ccagctcgcg
    16741 accatggcct cgacgtccgg ccactcgggc gcggcctcgt ccgcgtcgcg gtattcccac
    16801 tcgatcgccc gcaccagcaa ggcggtcagg tcggggaacc ggcggtacac cgtggcgcgg
    16861 gtgaccccgg cgagccgcgc cacctgttcg acgctgacct gggcgacgcc gcgttcgagc
    16921 agcagatcga tcgcggcggt gaggatcgcc tcgtccgctc gcgcgttgcg cggcctgcca
    16981 gggggtcgcg cggtgccttc cgatcccatg gtagttacaa tacagacctg tatcgtattg
    17041 caactaccat gggacgcgga tcactggtcc tgctgtccgg gtgaccgtcg aacgggtgct
    17101 gcgcttccgt cgcgatgtcc cgtactttcc ttgggggaca aggaaagggg accgtcatgg
    17161 agaagtcgcg aaggaccgcg tccgccgccg cggcggcact ggtgatcggg ctgggcggcg
    17221 gtgtcgcctc cgcctcggcc accgctcaac cagccaccga acccgccgcc gcggtcggca
    17281 cgccgtccaa gcggacggag ctgtacttcg gcaccgagaa gccgacgggc ggcgtggtca
    17341 cccccgagga cttcgagaac ttcgtggaca aggagatcac gcccgccttc ccggacggcc
    17401 tgaccaagtt caccgccacc gggcagtgga aacgcggggc ggagatcgtg aaggagacga
    17461 cgtacgtggt cgtgctgttc tacccgctgg gcaaccggaa ggccgacggc gagatcgagg
    17521 agatccgcgc cgactacaag aagttcttcg accaggactc ggtggccaga gccgacgaca
    17581 cgcaacgcgt ctctttctag cggggcccgt tgaacgcccc gaaggtggcc ttcggggcgg
    17641 tagatgccct gaaagccact ttcggggcgt gcgcgcgggg acccgggcgg cgacaccgcg
    17701 gctggaagtc catagtggac tgtcaggggc ggtcggcgag cgtggtgtcc gcgccgccgg
    17761 tcctgctgat cagggtcacg tgcgacgggc cgatcttctc gagcgtccgc gcgagcaggt
    17821 cctcgtggac gcgggagcgg cgcgcttcga gccggaccac cgggcggttc ggggtggtct
    17881 ggtccagctg ccccgcccgg atccccgccg ggacggcctg gcgcgaacgc agccgcacgc
    17941 cgatgaccat ggtgtccggc gagccgggcg accggtcgtg gtcgagcacg atcttctcga
    18001 cggcgtccca cggaaccgtc cagcggccga tgccgaggtt gccggggtgc aggtacagca
    18061 cggtgttttc ccgctggtag cgccggatgg ccgcggcggg accgccgatg agcagcgcgg
    18121 tcccgagcgc ggtgatccac ttctggtcga gcaggacgcc gagcgcgccg agcaggaaca
    18181 ccgcgccgag cacgagcgcg atgccgagcc agaacaggcc gaaccgggcg gaggagaacg
    18241 ggcgggcgat gcggtactgc ttggtcatgg gggccacctg agaacgtcgt ttcgctgtcc
    18301 ccggtgaaga ccccgtcccg ccgggaatgg ttggggtgct tcagaacggc cgcgcgcgga
    18361 tctcggcgat cagggaccgg ggcagggcta gtgcgggatc cgtgccgggc tgctcggcgg
    18421 cgaggcgcac ccggcaggcg gcggcgtgca gcgcttcctg cgccgcggcc gtgtttccca
    18481 gcagcagcaa cgcgatcccg aacagccgct gccggtacgc gggatcggac agggagaact
    18541 cgtcgccggg ctccggtgtg cgggcgctca tggcgcggtc ttcaagaacg cctcgatccg
    18601 tttgaccgcg gtgtgcacgt tcttcttcgc ggccccttcg gtgatcccca tgatcttggc
    18661 ggtctccttg taggtgtacc cgccgaaacc gtgcagcacc acggtttcgc gttcgcgcgg
    18721 ctgcagcgcg tcgagcagcc ggagcaggta ctgccgcagc aggaccagtt cgtcgacggc
    18781 cagcccggcc cgttcgcgga gcacggcgat cttgtcgtcc ccgtcgcctt ccacgcgttc
    18841 gcgggtgacg atcatccgcc gcatcgcgtc gttggtggcg ttcttgaccg aggtccacac
    18901 gtaggcccgc agcgactccg gttcggtgat ctcgggcttg cgcgcgaaca cccgcatgaa
    18961 cgccgtctgc accacgtcct ccgcctcggc ccggttgtcg ctgaggtgct cgcgggcgta
    19021 gctggtgaac gcttcccgcg acccgtcgaa gagttcgacc agcatcccgg tgaaccgcgc
    19081 tccgccgtcc ggtgcggtgg tggacccgga gaccctggtg atcccgccac gcggcgccgg
    19141 gacggcgaac cggcccggcg ccgccgcgaa gtcccgcagc agcgcgccga tgagcgcgct
    19201 gagcgcgtcg tcgtgcccgg ccgcctggtc gtcgaaggtc atgccgggcc tttcctcgcc
    19261 gagctggttc tggggcagca ctgtggtgtt catatcgagt gggaccccgg ctcggcgaaa
    19321 aaagttgggt cactcgatcg ggtgatccag gccgagggct tcgcggtgcg ccgccgagat
    19381 cccgcggacc acccgccacg ccctcgcctg cgccagggtg gccccggctt cgagcagctt
    19441 cgccgcgtcg atgctcgcac gcggcgagaa catcaccggt agccgcttct cggtagcggc
    19501 ggcccgcagc ccgcgcacct cttcgaggat ccgcaccgct tcggcctgcc gcgacggggc
    19561 ctgagccagt gccacccggc gttccagccg ctcgtcgacc tggacttcga gtaccgcgaa
    19621 ccggtcgagc gtcgccgcgt ccagcgcctg cctgccgacg tactgccggt ccccgccggt
    19681 gccgtaggtg ttcccggtgg cgactaggca gaagtcccgg tgcgcggtca ccatgccgtc
    19741 ggcgaacgcg cagaccccga gcgcgagcgc ctggttgagc tccgcgagca ggccggggtg
    19801 cccgctgtcc agttcgtcga gcagcatcag cccgccgtgt tcgaaggcac gccggaacgg
    19861 ggtgtcgtga tagtggccgt gcgcgtcgaa gtagccgaag accttgctca tcggggtggt
    19921 cgggcccagt gacaacgcgt ggaaggcgag cccgaacgcc tccgcggcct gttcggccat
    19981 cgtggacttg ccggtgccag ccgggccgac cagcaggacg tggcagcggg cgcgcagcgc
    20041 gaggaggaga tcgggcagca cggcgtgggt gtcaccggag acctcggccg ggtccggccg
    20101 gtgcccgtcg acctggatga tcctcggtga ctcctcggcg cacaccttcg ccgcttcgtc
    20161 acgggcgact tcgcgcattc gcccggcgca gtcccgcagc agttccttcg cggtcgtttc
    20221 cgcgaccttc gccgcgcgca cctcggtttc gctgcgatcg ggctgccacc cggacagcag
    20281 tttttcgaag gtccccttgg ccgtggcggc cgcgatccgg cgcaccgaag cgtcgttgcg
    20341 ctcgatccgg tccgaaaccc ggcgcgcgat cgcggccgcc gcctcggtcg cggtttcgcg
    20401 agcgacatcc gtgacgagtt tttcgtgcac tcgcacggct tccagtgccg cttccttcgc
    20461 ggatcggcgt acctcggcaa gggtgctttc gcgcatcacg ggtccttttg cgtcgctcgg
    20521 ccggacaccg gtaccgaccg ctcgtgcgcc ggaaaggttg ggccggcact caggaatggt
    20581 gatacgaccg gacggtcgcg ttcggataac ccattcccat tcccacgggc tgtctttcct
    20641 ccttcgcgca cgtgccgccc gcgtagaccg cctggttctc gttggcgtgg ctgtagatcg
    20701 agcgggccgt gaagctcaac gggtggcagg tggcaccgct cgaatgaacc atcggcatcg
    20761 cgaccatctc accggtgaag tcgggcccct gccagaagca gacgtacagc tcgcggcact
    20821 gcgcgctgac agacggcggc acgggccccg gcaccagcga cggcgggccg gtcgacggtg
    20881 gcgggggcgg cggtgcgctg ctggccgaac tgggcggcgc cacgcgggaa gacggcggcg
    20941 ggctcgcgga cgtgctcggg ggcggggagg acggggtgcc ggtgctcggg ctgggcggcg
    21001 cggcactgct gctcggcagg ccacctccgg cggcgggtgc ggcatccccg ccggggcgcc
    21061 gggtctggtt caccgcgacc gtggtgacca ccaccgtcgc ggccaccacc agcacggccg
    21121 caccggtcgc cgcggccagc cgccagcgcc ggtggcggga cccggccctg atgaaatccc
    21181 gttgccgcgc ggtcagttcg gcgccgcgtt cgccgagcca cttccgcgcc tcggagaggg
    21241 aacctccgcg cggcagcagg tcccgcgcgc cgtcggccgc ggcccagcgc gtgatctgct
    21301 ggtcgaggtg atcgcgccag tgcaggaacg cgcgatcgtc ctccagccag ccgcgcagcc
    21361 gcggccagtg gtcgatcagc gcctggtggg ccagttcggc gtgcggctcg ccgtccatac
    21421 cctggccgac cacgaccagc ctgctcttcg ccaggtggtg cgcgaggcgc cgcaggccgg
    21481 ggtcgagcgc ggccatcagg accgcgcggc gcgagaactg ctcgccgtcg gggcgggcga
    21541 gctgggtgaa gaagcggcgc aggaactcga cttcgcccct gccgacgaac tcggcgatcg
    21601 cggattccgc cgcgcgggtc accgcgccgg cgaccccgcc gatcccggtg taggccgccg
    21661 tggtcatgaa cccgccgtcg cgttcttccc acagctgcgt caacagcgat tccaccagcg
    21721 gcagctgtcc cggttcggca ccggcgtcgt cgaggatgcg gtcgacgagc ccgtcctcga
    21781 agtacaggcc gggcgccctg gtcgacggcc cgacgatcgc cgcgcgcagc tgcgccggtc
    21841 ccatcggggc gagcgtgacg atcgcggtgc cgagcgcgtc cttggtgtcc tcggtgagca
    21901 gatcgcccat cgcgttccag cgcagcgtga ccagtacgcg cagcggcacg ctcccgccgg
    21961 cgccgagcag ccggacgagc agccgcagga actccttggc cgcgtcgagg tcctcggcgg
    22021 ccagttcctc gaactggtcg aggaagagca ccatccccgc ttcgcgaccg gcttcgagca
    22081 acgcgttcgc cagccaccgc accgcccccg gatcggtggg cagccgcacg gccagcgcct
    22141 gcgcccagcg gaactggtcg gtggctggca ggtcagggtg caggagccgg gccatggcga
    22201 gcgcgagcga aagcgggccc gtcacaccgg gcatcggccg gaacggcacg atcgccgcgc
    22261 ccgcggcccg caggcgcggc agcatgcccg cgcggatcaa ggaggacttg ccggtcccgg
    22321 aatgccccat caccgcgacc agcggcctgc gcgcgacggc gtcggagagc cgctggagat
    22381 cgtcctcgcg gccgaagaag aagtccgcgt gccgttcgtc gaacggttcc aggccgcggt
    22441 acgggttcgg cacccggccg ggatcggtgc cgaagacgcg ctcgatcggg atgaggtacg
    22501 ccgtggccac cagcgggccg gcgtgcgcgg cgacggtcat cccgacgacc gccctggcgt
    22561 cggagtccca taccggggaa ccgctgaacc cgccgacgat cggctgctcg ccgggcgtgc
    22621 cttcgagctg gagccactgc gtgccctgca gatcgcggaa cacccccgac gaccagacgc
    22681 cgtcggggaa gtccccgggg aacccgagca cgcggaattc gtgcccccag gcgctttcca
    22741 ccctggccag cggtggcacc tgcgccgcgt ccggggcggg ctcggcgagt tccagcagcg
    22801 cgatgtcacc ggtgccgtcc ggcaggatcg gcagccaggt caccaccgcg gcggagaacc
    22861 gcttcgcacg ggaacccggc ccggtgacga gcgggaagtc gaccgtgcag gccgccgagg
    22921 gccgctccca gttcgcgggg tcgccgccca ccgcggcggt gacgacgtgc gcgcacgtcg
    22981 cgatgacgtt cggtgccagc aggaagccgg cgcccgccac cgtgccgtcc gggcccagca
    23041 cgcggacgac ggcgcgcccc agcggaccgt gaccgtcccc cgaccggtct gccatgccga
    23101 actttcctcc tgagtcgagt ggtggacagg ttaccgtccg cgttcttccc gcggccgggg
    23161 ccggggcgtc cacctccttg acgccgccgg gcagggaagc gtttcagttc agcaggccca
    23221 gcccgcggaa caggtcttcg caccacgtcc gcgccgagtc gagcgtggcc cagcgggtgt
    23281 cgtgccggtc caggttcggg aacacgtacg gatcggcgat gtcctccgcc aggtcctcgg
    23341 cacgggacgg gtgcgggatc ccgtaccgcg accgtttcag caacgccgcc gagcggcggg
    23401 cggagctgtc ccagacgccg aaccacagcc tgcgcagcat cgcgggatgc gccatcgcga
    23461 acaggagcct gccgacgtcg agcggttccc cggccgggat caccttcgcc accgcggaaa
    23521 accgctcccg cccgacccgc gccgaaaaac cggaccagat ctcgacgctg tgccccgctt
    23581 cgatgatcgc cgtgcacaac gcggccagcg cgatccccct gttccggatc gtccggtgcg
    23641 cgacggtgtg cgaacaggac gcggggacca ggaaggtgac caccctgccc cgcgccgagg
    23701 tccaggacgg gacggcgtcg accatgcact ccggcacccc gctgaggtag gcgccgacgt
    23761 cgacctcgcc gccggtgacg tcccagcacg gcagcagcgt cgtggagcgg aggccgtcgc
    23821 cggaccgttc gcggagtgcg gcgatgccga cgtccacttc gggcagtgcc cgcgtccagc
    23881 ccgccgcggc gagttcgagt gcttcgtccc aggacgcgcc ggcccaccgg gaatccccgt
    23941 ggcggcccgc cccgtccggg atggaatcgg gtgcccgcgc gaggtcgagg aattccgtcc
    24001 aggacggcac cggcggcagg ctcgtcacct cgcccccgat tcggtggcga gcgcctccgc
    24061 ggcgtggagc accgcgtcga tctggacggc cgtggctccg tgctcggcga cgatcgcgcg
    24121 cgagagcagg atgtgcagca cggtcaccga gtccgccggt acgccgtcga ggagcgccgt
    24181 cgcgccgagc gtcgcgcgga tcaagcgcac cgccgcggtg gcgtcgatcc gctggtgcgt
    24241 cccggcccag gccggcgcgg agtcgacgaa cgccgggatc cgccggtcgc ccggcatcgc
    24301 gaaccggcgc gcggccagca cggtgaacac ggcggaagcg agcgtggcga actcggcgtt
    24361 ctcgcctggc cggtgccgcc ggagtgaacc ggccaggtcg gcgcacacca gcagttcccg
    24421 gatcagcggc cgggacggca tcgcggtcat cgtggccctc ctccgaagaa gtccttgatg
    24481 gactgccact tcttgacggc gcagataccg ctgaccgtca cgaccatgac cgacgaggtg
    24541 aaatccgccg gtgccgcggg ctggtcgtgc gcggccggat gcggcccggc cggttggacc
    24601 ggggcgcctt tgacgcccgg tttccgcgtc aaccccctct gcgcgtcctc gaacgtctcg
    24661 gggaacttga ccagggtgcc cgacccgctt cccttcttct ccgtgctttc gatctcgtcc
    24721 tcgaccccgg cttcccggct gctcgtggtc ccgcgcgact tccgcttcgg gccgtccagc
    24781 ggtggcaggt tgttcgtcag ccgcgagtgg aacaggagcc acatcgcgta ggcgatgtcg
    24841 gccgcgatcg ccagccccag cagggtgtat gccccgagtg cggcgatgtc gccgcagccg
    24901 aacccggaca ggtcggccgc gccgtagctg acctgtccgc actggctggc gagtgccgcg
    24961 gtgggaacgc agagcggcag gccgagcgcc accgcgatga tgatcatcaa ccgccagaac
    25021 atgtcagtcc ctcccccgtg caccgttgcc gcagcgcgga tatctcggtc cgcagcgcgc
    25081 gttcgctcgc gggcgggcgc ggatccgggt cgcgcgcgag ccgccatctc gtcgcggcca
    25141 gttcgagctg ccggtcccgc aaccgtccga agtggacata gccgcgaacg ccgtaccgct
    25201 ggcaggcccg cagccgttcg gcgatccgca gccgcggatg ggacagcacc gggagttcgg
    25261 cgcgcgtgac ggccccgagc ccggtggcgg attcgacgag cagcaccgcc cgcagcgccc
    25321 gtgcttcgtg gcgcgcgccc agccacagcg ccacgccgac gaccacgagc agcggcccgc
    25381 tcagcgtcgc gtagttcaac ggcatcgcca gcagcacttc ggcttcctgg ctgccgccgt
    25441 gccacggcat gccgccgttg aaggacgcga agttccagaa gaagtgcccg agcacggccg
    25501 tcgcgaaccc ggccgcgacg cagacgacgc gccccgccca cccgccgtac cggctcgcca
    25561 gtcccaccgc ggccccgaac aggccggtga acaggacgtg gccgaacagc accccgccgg
    25621 cccactgccg cacccacacg tggaacgcgg cctggtcgaa gttcgccatg gcgaaccgcg
    25681 cggtttccgc gaagttgaac ccggcgcccg tcatcccgcc gagcacggca ccggtcagca
    25741 cgccgtcgaa ccggcggcgg agcaggtgga agacgacgag cacaccggcc gccttggcgc
    25801 attcctccca caacggggcc gcgagcacca tcgacgcggg ctgcgcgccg aggtccgccg
    25861 gaacccagtc gtcggacagg gaccggagcg cgagcgcgct gtgggcggtt tgggcgaggc
    25921 agccgaaggt gaacgcgaac gtcacacccc agccgaacgc gagcagcgag aaccgcagcg
    25981 ggatccgccg gaacctcggc agccggtgca gcacccacac cgcgaacacg gcgccgggca
    26041 cggccatcgc ggtgcccgcc gggttcacca ggaacacctt ggcgaacggg aaaaccggca
    26101 ttccggtggc gcagaccagt gccgcgcacc ggttcgcggc cacgagcttc cgcgcccgct
    26161 cgccgtcacg ggcgaaccgg gcgatgaccg cgggccccgt cacgagcagc gcggccccgc
    26221 acccggtacc gacggccatg ccgatcaggt aggtcgcggc catcccgccc ggcgtcgggt
    26281 agcggtcccc ggggaacgac atcagcagtt gcccgcgcca ccacgggaac agcagcaggc
    26341 acgcggtcgc cagcaccacg gtcgcgagcc agaccgctgc ggtcgtccgt accgcgaagc
    26401 ctccccgtcg gagaacggcg gtcacgccgg gcatttccgg tccaccgcct cccgcaaccg
    26461 ggacagtccg gtaaggcccc gcagtgccgc gggcccgtcg cccagccgtt cgaggtcccc
    26521 ggcgaccgcc agcgcggcgc cgcgcagttc ctggtcgctc accgcggcgg ccccgctctc
    26581 gaggcgtccg ccgatttcgc gcagcttccc ggtcagcccg gtcaggtcac cggagacggt
    26641 ccgcgcgtcg gccacgtctt tcgccgccgt tcgcaccacc gagcccagtt cgccgcacct
    26701 cctcgcgtcc tccgaggact gggcgaagca ggaacacagc gagaggctga tggcgaacgc
    26761 cgttcccgct gcggcagccc gccgcggtat cttccgtttt ccgttctgag acaagtttct
    26821 taccctccag aaaagtcgca ttaggacggt catcccaggt cgaccgggat gtcgaacggc
    26881 gccggtgcgg gggaccagct gcccgccgcc ttcttcttga ggcgggtggc ggtcacctcg
    26941 gccgcgccga tgctcgcccg caccgtgccg cgctggaact ccgccgggac ggcgaacgtc
    27001 atcagcccgc cggacttgag cggccagggc ccgagcacct ccgtgctcat cgtggtgctc
    27061 cccggttcag cggggatcgc ggtcccgtcg ggcagccgga gcgagaacac cgccggatcc
    27121 gagagtgcga ggtcgaagag cggtgagaac ggatcgaacg gccgggagac gaccggcctc
    27181 ggcaccacca gccacgcccc gccgggcggt gcccagccgc gccgcggggt gtagggcgcc
    27241 agcgtcgcgg tgggtttgtc ggtcaggtgc gcgggatcca tggtcttgaa cccggccgcg
    27301 aactccaccg gggtgcggcc gccgcccagc ggcgtggaga tcccgccgga aagatggccc
    27361 gtccaggtca gttccgcgga gttcctgcgg tagtagcccg cgatcgcgtc gggccccctg
    27421 cggccggtgc gcaggtccat cgtctgggtg cgcccggcgt cggtcaccct gatcgacacc
    27481 ggcgccccgg cgggcacgct ggccaccacg accgcgctgt cgagcttgac gtcgacgccg
    27541 cttttcggcg gggtcagcgg aatccggtgc agcgcggtgg gcgcgccgcc gaccaccagc
    27601 tccgctttcg gtttcggatc gtcttcgtcc ggcacccact gcccggctcg cacccgcgag
    27661 tcggcggcga cgaccacgag ctcctgcccc ggttcggccc gccgctcgcc gatgcccgac
    27721 gccgccaccg gtcccttgat cgccttgccg acggcgaagg cttccacccc gaaggcgaag
    27781 aacgggccgt cgagccggcc ttgaccgtcc tcataggact gaacggtcag ctcggaaccc
    27841 agccacaccg gcggggagcc cgccgtgcgc tcgaactcct ccaccgagtt cgggcgctgc
    27901 gcgggtaatc ccgcgacttc cggcggcggc tccgagccgt tcgtgcacga ggccaccagc
    27961 cccgcgcaca ccagcccaac gacaacggca ccacaccgca tccgtcctca cctcccgcga
    28021 tcgacacacc acccaggaca gggcgggcac gcgaaaggtt gggcacggga acggagaacg
    28081 gcgttttcac ccgatggggg ccgggcagct caggtcggcc gccgggagct ttccggtggc
    28141 gaggtacgcg gcggcggggg cgtcgacgca cgggttcccg cgcaggaacg tcaccgccgg
    28201 gttcaagccg ccctgctcgg tgaccagccg ggaaccgggc aaggtcgcgt ggagccgctg
    28261 ggcgtcgcga taggcgagtg cgatgtcgtc ggtggcgtgc acgatcaacg cgggtggcag
    28321 gcccgcaccg gtgatcggca ccggagtgcg gggcgcccgc ggccagaacg cgcacggcga
    28381 gaggtaccag gtgttgttcc aggtcgcgaa cggggcggtg gcgtgcagct tcgtggcgtc
    28441 gtcgtgccac tggcgccaat cgcgcggcca cgcggtgtcg gcgcactgca cggcggtgaa
    28501 caccgcgtag tcgttgtcgc cgtgatgtgc cgcgatggcc tggtacgcgg tcacgacggc
    28561 cttttcgtcg ccgtggtgaa aggccgcgag ggtgttcgcg aggaacggcc acaacccgct
    28621 ttcccaagcc acgttgtgga acgtggcctc gaactcgaac gggccgacca ccccgcccgc
    28681 gggcttggcc ttcaccgcgc cgcgcgcgcc gtagtacgcc gcggccacgg tttccggcgc
    28741 ggtgccgagg tggtagacgt cgtccttgcc cgcgacccag gcgaagaagt ccttcgacct
    28801 ggcgtcgaaa ccggggtcct cctgctcgat gtagtgccgg taccagtcgg cgtcctggcg
    28861 cgcgacgctg tccagcaccg cccggcgcag cttcccgggg aacagggtgc cgtacaccga
    28921 gccgacgtag gtgccgtagc cgtaaccgag gtagtcgatg gtcggctgtc cgagcgcgcg
    28981 ccgcacgtcg tcgagatcgc gcgcgctgtc ctcggtgctc atgtgcggca gcaacgagcc
    29041 gtacttcgcc gcgcatttca tcgtgtacgc cagcgggcgg gacagcaggc gcagttcctc
    29101 gcccgcgttc gacggcaccg gatcgggcca cggcggggcg aagtaatcct tgtcgcagct
    29161 catcgacggc gtgctcgcgc cgactccgcg cgggtcgatg ccgatgatgt cgtagctcgc
    29221 gacgaggtcc ggcggcatcg caccggcgac ggtgcccgcc accgcgcgcc cggtgatgcc
    29281 ggggccgccg gggttgacca ccagcacgcc cttcggcgcg gcggccttct tgcggctcag
    29341 cgccagtgtc acggtcgggc cgtgcggtcg cgcgtgatcc agtggcacgg ccagggtggc
    29401 gcagtccagg ccgagcttgg ccaggtccgc ctccgcgcac ggcgcccacg gcaggccggg
    29461 ttgcgcggcg gcgggcatgg cgggcacgag gccggtcacg aggacggccg ccgcgacggc
    29521 ggccctcagc ttcttcatgc gtgttcctcc acagtggacg gtcgatcgac tgcgctcgcg
    29581 gtggatcggc ggatggtcga ccggagcacc accggggcca tcagggaggt cgcgatcgcc
    29641 agcagcagca cggtcgcgta catgccgggg gtgagcagcc cgaggccgcg cccgaccgag
    29701 gcgaccacga ccccgaccac gccccgcgcg ttgaggcccg cgccgaccga cagcgcgtcc
    29761 cagtgcgcca gcccgccgat ccggccgccc gcgtacccgc cgccgaactt cgtcgccgcg
    29821 gcgaccagca gcaccacggc ggccatcgcc agcgtcgcgg cgtcggcgag gttcgtgagg
    29881 tcgacccgga ggccgacggt ggccaggaac agcggggcga gcacggacat caccatgatc
    29941 cgcagcggtt cgaggcgcgc ccggtcgagc ccggggcagc tgcccaccac gaccccggcg
    30001 acgaacgcgc cgaacaccgc ctccagcttg agcgcctggc tcgccgccgc gccgagcgaa
    30061 accacggcga ccacggtgac gatcagcggg ccgggaccgc tcgaccggct cgccctggtc
    30121 agcgccagcc gcaccagcgg gcggacgacc agtcccgcgg cgagcaggaa cccgagcagc
    30181 acgctgatcg acatcagcac cgaaccgggg tgcacaccgg ccaccgccat cgccgagacg
    30241 atcgagagca gcagccagcc gatcgcgtcg tcgaacacgc ccgcggtgag gatcagcttg
    30301 cccaccctgg tttccagcag gttcatgtcg gcgagggtct tggcgatcac cgggatcgcg
    30361 gtgacgccca tcgcgacgcc gaggaacagg gcgaacacgg tgcggtccac gccgccgggg
    30421 aggaaccggt cgggcatcag gtagccggcg agcacgccgc cgccgatcgg gagcagcacc
    30481 ccgcacaccg cgaccgacga cgcgggtttc acctggtccc tgagctgacc cagttcgagg
    30541 gtcagtccgg tcaacccgac caggagcacc acgccgacct ggccgacgga gtccagcagg
    30601 tgtgcctgct gggcgtccgg cgggaacagc cacgaggtga ccgaggggat cgccgcgccg
    30661 agcagggacg ggccgagcag cacaccggcg gccagctcgc cgaccagtgg tggcagcgaa
    30721 aaccggaccg cgagcctgcc gaacaggagc gcgagcgtga gcagcacgcc gacctgcagc
    30781 aggaacagcc acagcgaatc ggccgcgatc gggggcggcg gctgcgccac cgaggccgac
    30841 accgccgtcg cggcgatcac ggttcgacgg tcccggtgag cgcgggctcc tcttccgcgc
    30901 cggggatgcg gaacagctcc gacatcgcga gcctgccgga gatcaccgcg acgaacgctt
    30961 cgcgcgcgtt ggggtaccgc tcgttgaaat cggccatcga ccgcgcctgc tcgaagtagt
    31021 cttcgcgatc acgcgtcggg tcgtagaaga accgcacgta gtccaggaag ctcgacacca
    31081 tgttgtgcac gcccgcggcg taggcggcca gcgcgcgatc ggcgagatcg ggcctgcgca
    31141 acaccgtgtc gacggccttg gccgccgcgt cggcaccgag cacggccagg cacaccccgc
    31201 cggagaacaa cgggtcgatg aacccgctcg cgtcccctgt ggacagccag cccggcccgg
    31261 tgaccgcggc cgagcggtag gaccagtcgc gtgtggaccg gaactcggcg acccgcttcg
    31321 cgccgagcag aaggcgtttc agctgcttgc tttccgcgac accggcttcg tagagctcgt
    31381 cgatcgacgg accgccggaa accaggctcg cggtcggggt cacgtaaccg acgctgagcc
    31441 gccgggtttc ggtttccacc gggatcgccc agaaccagcc gtgcgacacc cgctccacca
    31501 ggatgttgcc gagctggccg tcgggcaggt ccgcggtgtc ctcgaagtag gtccagtagg
    31561 cgaggttgcg caggtcttcg gcccactcga tggtggtcag cttcctggac agcaccctcg
    31621 actgcccgga cgcgtcgacc acgagcgggg cgcgcgcttc ggtggtctcg ccgcccgctt
    31681 cgtagcggac accggtcacc ctgccgtttt cgagaagcgg ttctttgacg gtcgcctctt
    31741 cgaccacggt cacgccgagt tcgcgcgcgt ggtcgagcag gatctcgtcg aattcggccc
    31801 ggcgcacgtg gaacgagtag tcgtacgggc cgtcgatctc ggcgaagttg acgttccaca
    31861 gatcgcggtt cttgccccac acgatgctga gcccgttctt gcgcgggaaa ccgacccgtt
    31921 ccaggcgttc ggtgacgccg agctcgtcga acaccgagag catcccggtg atcagcgact
    31981 cgccgatgtg gtaccggggg aagagttcgc gctcgaggac cagcacccgg tgcccgcgct
    32041 gggcgagcaa cccggcggtg gtggcaccgg ccggtccgcc gcccacgacc actacgtcga
    32101 attccacagc catccccaag cccttctgcg tggcgtacgg ttgcttcacc gtgctactgg
    32161 cgatcctgat cggtgccagg ggagtgagaa atccccaacc gggccacctg agctgtacgg
    32221 ctggggtagc cggtgggcta gggccgtggc ggcacggcga tcgaccacgg gaggattccg
    32281 cccatgtcgc atctctacca ggagccgaac gcctaccggc ggcgcctgac catcccgttc
    32341 agcgggctgc acaccagggc ggccgcgcac gcgcgctcgg cggcgccgga atccggtgcg
    32401 gtgctggaca tcggctgcgg gccgggcacg ctcgcgctgc ggatcgcgcg gtcgcgcccg
    32461 gatctgcggg tgtccggagt ggacccgtcg gccgcgatgg tggactacgc cgcgaaagcg
    32521 gcgagcaggc gcggtttcgc gggcagggtg gacttcgcgg tggggcaggc cgccaggatg
    32581 ccgttcgagc cgggctcgtt cgacgtggtg gtgtccacga tgagcttcca tcactgggcc
    32641 gcgttgccgg acgtggtgcg cgagctgcgg cgggtggtcc ggccgggcgg ccggatcttc
    32701 gtctacgaca tgcgtgccgc ctactacgac gggctgcgtt cggcggtcga agcggtcgct
    32761 cctgaatgga cgttccggcg gaagttcctg tggctgcggg ttttcccgtc gctgatgttc
    32821 ggctgcgcgg agatcagcgt tccgtcgtga cggtcagcac ggcgctcgcg gcgttgtagc
    32881 cctgcgtgcc gccgaccatc agcacccggt cgcccgccga gagctggccc gtggcgagca
    32941 ggtggtgcag cgacacgacc tggtcgcacg cgccgaggtg cccgaccgtg cggccgaagt
    33001 cccaagtgga cttcgccatc ggcaggccga gcggctgcat gatgccgagg tcgacgaacg
    33061 gcgcgcccgc gttgacgaac accaccctgg ccagctcgcc cgcgtccact tcggcctcgg
    33121 ccatcgcttg ccgcgccgcg gaaaagtaca tcgcggtgaa catccgccgc agttcgaacg
    33181 ggtcgtagcc cgccgcggcc acgaattcgc cggaccgggt cacgacgtcg atcggcccgt
    33241 cgcggacggc ggtctcctcc gacggcggcg cggcaccgcg gtgcaggccc tccagttcgg
    33301 ggaacgtggt ggagcagacg gcgtccaccc tggcgatccc gtgttcgcgt cccagcagca
    33361 ccgcgcaccc ggcgtcgccg acgtgcatcc cgaaacccgc gctgcgccac cggtccatga
    33421 gcgggctttc gccccgcagc gcggtggtga gcagcgcggt ggcggcgtgc tcggacagcg
    33481 ccagccatcc cgcggccagc tccatcgcgg cgaacatccc gttgcagccc tgccggactt
    33541 cgtggcaggg ccccggatcg cagcccagtt cgcggagcac gtacccggcg ggcgaccacc
    33601 cgtcgggtcc ttccgggagc atcgtcgcgt gcaccagcag gtcgagatct cctggtttca
    33661 catcggcgtc ggacaacgct tcgcggccag ccgcgacggc catgtcgaca ccgctcgtgc
    33721 cgtcgcctgc ggcgacgctg agcagaccgc tgtgcgcgat ctgctcagcg ccgcagtacc
    33781 cggccgcgac cgcttcgtcc gcggtgatcc ggccctcggg caggtgcacg ccgatcccgc
    33841 ggaggaagag cccgtgcggt ttcatgtccc ggctcaggcc tggccaggtc cggcccacac
    33901 ggcgccgagg tacgggtgcc agacgtggtc ggggtcgttt tccaccgcct tcaggatttc
    33961 gcgcatgtcc tccagcgcct tcggcggttc gccgtcgtag acgtcaccct gcagcatccg
    34021 cagcacgtcg atgcggtagc gcgggtcctt cacgaacgcg gtgaacagca cgttgagccg
    34081 gtagaagatg gcgatgaact cgtaccagta gccgaccgcc ttcttcagct tcgcctcgta
    34141 ggtcgcgaaa ctgctcctgc cgaagccgtg cccgccttcg tgcgcggcga tgatgtcgcg
    34201 ggacacgagc cgcgcgctgt tcatcgcgac gctcaccccg ctggagaaga tcgggtccac
    34261 gaaccgcgcg gcgtccccga tcagcacgaa ccggtcgccc gccatttccc gcatccggta
    34321 gctgtaatcg ccttccgcct tgaacgggcg gatctggcgc gccttccgca gcgccttgct
    34381 cagctccggg cgggtgtcca cgaagtccca gaacagttcg tcgggtgacg cgctcgcgga
    34441 ggtgaagttc ttcttctgcg tcaccacgcc gaagctcgtg acggtgtcgg tgatcgggat
    34501 ctgccacacc caggagtccc gcatcgccag ccagtgcacg tagatgaagt cctcttcgtg
    34561 gtcctcggtg acgaacgcgg tccggtcgaa gtcctcgaac cacgcgtgca gcgcgtactg
    34621 gttgaacacc gggtccggga tcttcgtctt cagctgcttg ccgagcaggg tctgcctgcc
    34681 ggaggcgtcc acgacgaggt tcgcggtgta ggtgacgttc gcgccggcga tccggcagtt
    34741 cagcgtgacc acctggtcgt cggagaagtc cacgttcagc acgcgggcgc cgcacacgac
    34801 cttcgcgccc tgcgcctcgg cgttcttcag caggatgagg tcgaacttgc cgcggtcgac
    34861 gtggtaggtg tagtcgcggt cgacgccttc ctggtcgcgt tccacgaact gcaccacggc
    34921 gggcaggttg tggctgagcc cggcgaaacc gttgttgggc agggacacgg agttcgcggt
    34981 cgtccacgcc gcgccgtact tcttcgggaa gcccgcggcg tccaccgcgg gcatcgcgcc
    35041 gctttcgacc agcggcgggg tggcggcggg taccagtgac tcgccgacgt ggggccgcgg
    35101 gaagatttcg ctttcgagca ggagcacgga aaggccggcc ttggcgaggt acgcggccgc
    35161 cgtcgagcca gccgggccgc cgccgatgac cgccacatcg aagtctgctt gcatgcactc
    35221 cagtgttcgg gcgccaccaa gaccgcgctt acaactcgct taacggcctg gatgagggaa
    35281 tttagcggtt cttcagtgcc ctgttggccg cggcggatcg gatggtcccc gttatggact
    35341 tcgacttggc tcccgagcag cagaagcgtg tcgacgcgct gcgcaccgcc gtgcggaccg
    35401 gtttgcccgg cgcggtgcgg agttccccgg acgcgcactt ctccaggacc gaatgggccg
    35461 ccgcggcggc actcggcctc accgggttgt gcctgccgtc cgcgttcggg ggcggcggcc
    35521 tcggcgcgct cgatgtcgcg ctgtgcctgg aagccttcgg tgacgagtgc gccgacaccg
    35581 ggctcgtgtt cggggtcgcc gctcatctgc tcgcctgcgt cgtgccgatc cgggacttcg
    35641 cttcggggag tctgctggac gagctggcgc cgggtttggc cgacggttcg gtgatcgcgg
    35701 cgaacgcgat gaccgaaccg gaggcgggtt ccgacgtcgg cgcgctcacc acgacggcga
    35761 cccgtgccga cggcggctac cggctcgacg gcgtgaagtc cttcgccagc aacggtccgc
    35821 tcgccgacgt gttcgtcacc tacgcggtca ccgacccgga tgcggccttc ctcggcatca
    35881 gcgcgttcgc ggtcccgcgc ggggtgcccg gcctgaagat cggcgggccg gtggccaaaa
    35941 cgggcctctg gggctgtccc gcgggcaggg tggagttcga cggctgcttc gtgccggagc
    36001 gctatcggct cggcgaagag ggccagggat cgggggtctt ccagcattcg atgggctggg
    36061 aacgggcctg cttgttcggg ctctacctcg gagtgctagc caggcagcta cgccagtgcg
    36121 tcgaccacgc gaggacgcgt cgccagttcg gcaggccgat cggggagttc caggcggttt
    36181 cgcaccggat cgcggacatg cgggcccggc tcgaagccgc gcggctgctg gtccaccggg
    36241 cctgctggct gctggacgag aacagggagc accgcgccgc cgcggccgtg tcgaagatga
    36301 ccgtttccga gaccgcgatc gcgaacagcc tcgacgcggt gcggatcttc ggcggcgccg
    36361 ggtacctggg cggggacagt gccggaaccc agctccggga ctgcgtgccg acggcgatct
    36421 tctccggcac gacggacatg cagaaggaaa tcctgacgcg ggagatgggc ctgtgaccct
    36481 cttgcacgaa gccgtgcggg ccaccgcgaa acgccatccc ggccgggtgg cggtgtccgg
    36541 tgtggacggt tcgctgagct acgccgaact cgaccggcgg gcggacgcgc tcgcggcgtc
    36601 cttcgtagcg gccggggtcg tgccgggcga ccgggtgctg atctgggcgg cgaagtcgtg
    36661 cgcggtggtg gtcgccatgc aggcggcact gcgcgccggt gccgcctacg tcccggtgga
    36721 cagcacttct ccggcgggcc gcgtcgcgac ggtcgtgcgg gactgcgccc cgcgcgtggt
    36781 gtgcgcttcg ccggaccgcg cggaggagat cgcgcggttt cttgaggaaa tgcccgtgtt
    36841 ctgcgatctc ggcgaccttc ccgaggccgc ggcacccgtg gcggtcgcgg gcggcgagga
    36901 cgatctggcg ttcatcctct acacctcggg ttcgaccggg accccgaagg gcgtgtgcct
    36961 cagccacgcc aacgcgatgg cgttcgtgcg gtgggcgatc gcggagctgg cgctcggcaa
    37021 ggaagaccgc ttggccaacc acgcgccgtt cagcttcgac ctctcggtgc tcgacctcta
    37081 cggcgcgctg tgcaccggcg ggtcggtcca cctggtcgcc gccgaactcg cgtacgcgcc
    37141 ggagcagctc gtggatttcc tgcggtggcg ggaaatcacc gtgtggtact cggtcccttc
    37201 ggcgctgctg ctgatgatgc gggacggcgg cctgctcgac cgtccggcgc ccgccgcgtt
    37261 gcgcgcggtg ctgttcgccg gggagccgtt cccgatcggc gcgctgcgcg atctcgcggg
    37321 ctggaccggg gcgcggctgc tgaacctgta cggccccacc gagaccaacg tgtgcaccgc
    37381 gcacgaagtc ggcgaggacg acctcgcgcg ggaccggccg gtgccgatcg gcaccgcggt
    37441 cagcggcgac accgtgtggg cggtcgtgga cggcgaagtg gcccggccgg gtgaagcggg
    37501 cgaactgcac gtgagcgggc cgtcggtgat gcgcggctac tggggccgcg aaccgcagcg
    37561 ggatccgtac ccgaccggag atctcgtgag cgtccgggaa gacggttcgt tcgagtacct
    37621 cggcaggcgc gacgcgatgg tcaaggtacg cgggcaccgc gtcgaactcg gcgacgtgga
    37681 agccgcgctg accgcgcatc cggacatcgc cgaggcggcc gcggtggtgc gcggttcggc
    37741 gctcggcggc cggatcgaag cgttcgtggt gccgcgtccc ggcgcccggc tcggcgtgct
    37801 cgcggtcaag cgccactgcg cggaacggct gccgacctac atgatcgccg acgacgcgca
    37861 cttcgtgccc gcgctgcccc ggaccgcgaa cgggaaggtc gaccgcgccg cactggcagt
    37921 acggcatccc tcgaacccga aggaaggtag caccgtatga actccgtgac cgaagaccgg
    37981 ctcatcgact tcatcaggga gaagttcctc gccggtgacc ccgacggcga gctgacggcg
    38041 gaaagtccct tgctgcagtg gggaatcctc gactccctca aggtcgccat cctgctgacc
    38101 ttcatccgcg agcagctcgg cgtgatcgtg ccgttccagc acctgagcgc gaagaacttc
    38161 ggcaccgtgc ggagcatggc ggtgctggtg accgagctcg gcgaacccgc acccgatcac
    38221 gcggactcgg tccactccat cccgccgtcg tgacagcgcg cgagcagttc gtcgtccgcc
    38281 cgcaggatcg cctgctgggt gcgctggagc atcttgccgg ggcggacgcc gagctggtcg
    38341 tcgagcgtct tgcgcgcgag gtggtagacg ttcaacgcgt ccgcctgccg gtcggaccgg
    38401 tacagcgcga ccatcagctg gcggtggaag gtctcccgca tcgggtgctc ggcgacgatc
    38461 gagtgcagcg gcccgaccag ttcccggtgc aggccccgct ccaggcggca gtcgatgagc
    38521 atttccaggc acgacaggcg ggtttcggtg agctgggtga cgaaaccgtc cacgacgtgc
    38581 cccgcccgca ggccgccgag cacgggaccg cgccacagcg cgagcgcgcc ttcgagcacc
    38641 cggatcgcgt cggtgaaccg gccgtgccgc atcagcgccc tgccgcgcga ggcgaggcgg
    38701 agcacgatgt cgaagtcgac ctcgtcggtg ccggtgcgca ggacgtaccc ggtctcgtgg
    38761 gtgagcacgg tgccgccggg gcacccggcc gcggtcagcg ccttgcgcag cttcgagagg
    38821 tagacgtgca ccgcggcggt ggcctggcgc ggtgggtcgt ccgcccagat ctcggcgatg
    38881 agctgatcgc gcgtgaccat ctcgcccgcg cggatcagca gcaccgacag gacggtctgc
    38941 acccgtcgcg ggccgacggc ggtggtgcgg ccgcggtcgg cgaggcgcac cgggcctagg
    39001 agttcgtagc gcatgtcgct ggcctcatct cgtgttctcg gtcgtctctg atccggtcgg
    39061 tggcgtggcg tccagcgcgg cgaggtcgac cttcccgtgc tgtgtggtcg gcatcgccgc
    39121 gtgcgcgcgg aaggccatcg gcaccatgtg cggcggcagc accccggccg cgaaccgccg
    39181 cagcaggtcc ccggtcggct cgtcaccgcc gacgcgggtg tagtgcgcgg tcagcagcgg
    39241 ttcgccgtgg gagttcgtgg cgacggtgac cgcgcactgg gcgagcagcg ggtgcccggc
    39301 gatcgcggcc tcgacctcgc cgagttcgac gcggaacccg cggatctgca cctggcggtc
    39361 cttgcggccg aggtagtgca ggccgccgga ctcgtcgagc acggcccagt ccccgctgcg
    39421 gaacgtgcgg agtccgttgt agacggtgaa gcgctcggcg gtgaggtccg cccggccgag
    39481 gtagccgtgc gtgactccgg caccggacac cagcagctga ccgggtgtac cggcgggaac
    39541 cgggcgcagg tcctcgtcca ccacggtgat ttccaggtgg ggcaacggaa tcccgatcgg
    39601 ggtcgagccc ggccacgcgg gttctccggt gtcgtccggc gtcagcacct ggtgcgtggc
    39661 gtgcaccgtc gtctcggtga tgccgtacat gttgaccagc gtcgcggccg gggccgcgcc
    39721 cagctcgtgc caccgccgga tcgcgggaag ctggatcgcc tcgccggaga agatcacgta
    39781 ccgcagcgcg ggcagccgta cctcgcgtgc ttccagttcc gccaccaggt agccgaacgc
    39841 ggtcggcacc tggttgagca cggtcacctc ctcggcgagg agcacctcgc tgaacgcgcg
    39901 aggatcggcc gccgtctctc gcgagatcat cacggccgtg ccgccgttga gcagcgcgcc
    39961 ccacagctcc cacacgctga cgtcgaagcc gtacccgcag aacaccgacc agacgtcgga
    40021 ggcgtcgaag tcgaacacct tgttgccgga gtccatcagc gcgagcacgt gctcgttgcc
    40081 gacgaacacg cccttcgggc ggccggttga ccccgacgtg tagatcacgt acgcggtacc
    40141 gggcggcacg tcgtggcggt cgcgccgctc gcccgtgacg accacctccg gctgccagga
    40201 atcccggccg ccgaccacgg tcagggtgat cctggcgtcg tcggcgatca gcttcgtccg
    40261 cgctgccggg taggccggat ccagtggcac gtaagcacat ccgtgcgcca ggatgcccag
    40321 gatgccgacc gcgaccggca ccccgcgggg catccgcagc ccgatcaggt cgccgggccg
    40381 cgcacccgcc gcggcgagcc ggtcgcgcag gtcctcggcg gccgagcgca gttcccggta
    40441 ggtgagcgac agttcgccgt cgacgagcgc gacctggccc gggtcgatca ggacctggtt
    40501 ttcgaacctc tcgtagagcg tcatggcggc ggtcacctct cgcggaacgg tgcgacggat
    40561 tcggggtcct tggtgaacag cacgtcgaac catccaccgt ccatatcgga cactgtggcg
    40621 agtacgcggt agccgagccc ggcgcccagc gcggaaagct cctccgggtc gacgcccggt
    40681 ggtggcggcg gccgggattc cagcgcggcg agcgccgcgt cctcctcggt cagccgcagg
    40741 ttcgggatcc cccggacgac cagctcggtg ccgtcgaggc ggccacgcag ctcggccgcg
    40801 ctgcggagat cgtttcccca caccagttcc ggcgcggccg gggtgtcccg gtgcgaccgg
    40861 gtgaggacca cgtcgtagcg gtgcctgctc aactcgttgt ggtgcaacgc ttccttgagc
    40921 cggatgtccg cggtgccggg gaggcccgcg aagaaaccgg ggtcgaccag cagctcctca
    40981 gccatgccga gcgcgcggtc cgcccgcgcc agcgcggccg cgccctgctc accgcgggcg
    41041 accgcgatcg cggcctggaa gctccggtgc gagcgcgggt tccggacgtc gccgacgaac
    41101 accgagccgc cgggcgcgag cagccggaac actccgtcga ggacttcgcg gaggtacccg
    41161 gtaccgggga agtactggac gacggagttc aggatcaccg tgtcgaagaa gccctccggc
    41221 agctcggtca gttcgtgcgc ggcgcactgc cggaccacga cacggtcggc gaggtcgtct
    41281 tcgagggtgt cgtcgagcca gtcgatcgcg gcgccggaag cgtcgatacc ccaataggaa
    41341 tcgcagcgcg gcgcgagttc ggtcagcagg agcccgctgc cgacgccgat ctccagcacc
    41401 cgcttcggcc gcagcgcgcg gatccgccgc accgtggcgt cgcgccattc ccgcatttcg
    41461 gcgagtggga tcggctcgcc ggtgtagctg ctggtccacc cggcgaagcg gctgtccggg
    41521 tcttcgccga gcgaaccggc gtacagctcg tcgtagaccg cctcccagcc gcggacgtgg
    41581 tcgtggtgta cggacatcag ccgttcgccc ccgcgggcgc ggggaggtgg ccggtactgg
    41641 cgaagcaggc cagcgcgccg cggaggtagg ccgcgtcgac cgggccgcag accaggtccg
    41701 cgctcagcgc ggacctggcg cggctggtgt cgtactcggc ttcgcgccag ccgtccgcga
    41761 cctgccgctt ccacgcgccg accacggaga gcacgagatc ccagcgcctg cccccgtcct
    41821 cggcggagcg ccgcacgagt tcggagtacc aggtgtcgat gtcgaccgaa cgcaggtcgt
    41881 acccggcgag ggtcatcgcc tcgcccacca cgcggaaggt gaacggctgc ggcgaaatca
    41941 ggtggtagcg cccgccgagt gactcctttt tccttgccag ggcggtgatc ccgtcggcga
    42001 cgtagtcgac aggggacgcg ggcatcggca ccgccgagtc gggcaccatg ccgaggtacg
    42061 cgcacgcctg cacgatctcg ctggtggcgt ccgacgggtt ccagtacgcg ggcgaggtgg
    42121 cgcccaccag cctggccgcc cggtagacca ccgtcggcac accgcgttcg tccgccagcg
    42181 ccagcagccg ctcggcgacc cacttcgaag cctcgtaacc gtgccgcgcc tccggcgggg
    42241 tcccggtgac cggcagttcg cggccgccga gctccggcgc gctgagcccg gcgtacgacg
    42301 ggtagtgcac gggtttggtc cggccggtcg cggcgagccg gagcacctcc ttggtgccgc
    42361 cgacgttcgt cgagcgcagc cgccggtagc tcggcagcgt gttcaccgtg cccccggcgt
    42421 ggtagatctc ctgcacgtcc gccgccagcg ccgcgaagtt ctcttcggac agtccgagca
    42481 gcggtttggt gaggttgccg cacaccgtgg tgatgcggcc gcggtactcc tcgcgccaca
    42541 gccccgccgc gcgcagcgtg tcgtgcacgc gcgccaggcc gtcgtccgga gtccggtccc
    42601 gcaccaggca ggtgacggtc gccgtgcccg agcgcagcag ccggtcgagc aggaaggagc
    42661 cgaggtagcc ggtggcgccg gtgagcagga accggctcgg cgacgggtgc cacgcggccg
    42721 ggccgatccc agtgatcgac tcgtcgagcg tgacgtcggc gctcagatct tggtgccctc
    42781 gtggcgcggg ctgcgcctcg ccgcccgctt cgatcagctt ggcgaggtcg cgcaccgtcg
    42841 ggttctcgaa cagcgcgtgc agcgtgacgg tgaggttcca gcggtcgcgg atctggttgg
    42901 tcgcgcgcgt gccgagcaac gagtgcaggc cgagttcgac gaggttgtcc gcggcgccga
    42961 cccggtcgac gtcgaggatg gcggccatca gctcggcgac cgctttctcg gtcggtgtgg
    43021 ctggcgggtc ggccggtccg gattccgcgg cgggggccgt ggtctcggca cgatcgccga
    43081 ggtgttcgag gccgtcgtcg tcggtcaccc tcgcccacag cccggaaacc gccccaccga
    43141 tctcgaccaa acccggtgcg ccgagcggaa cttcgtgccc ccgcgcgtcg acgagccgga
    43201 gcgggcggcc cgccggaagt gcggccgcca ggttggccgg gtcggcgcag gcgcgggcga
    43261 tacgccgccg ttcgtcctcc ggccgcacgt cgatgtccgc cagtgtggtg cccgcgtccg
    43321 aggccacgat cgccgcgagc acgtgccgca ccctggccag cagcagcccg gcctggtgcg
    43381 cgccgaaccg ccgccggtcg tgcaccagcc gcatcggcat ggtcgtcccc ggcatcacca
    43441 tcagcaccag cggtagctgc ggccgggtgt ccactgtgta cccgcggatc cggattccgc
    43501 ccaccggacc gccgaactcc gggatcggga tgttctggta ggtgaccagg ctttcgaaca
    43561 ggccccccgc ccgtgcgacg ccgctgtgcc gctggatgcc caccaggtcg gtcgcggtgt
    43621 gctcgcgcgc ggccagcacg gaatcctgga cgtgtcccag gtagtccagc accggctggt
    43681 cctcgcgcgg gcgggtgcgg atcgggaagg tgccgacgag acagccgacg atcgactcgg
    43741 cggcgggcac gtcggcgggc cggtgcgcga acgtcgttcc cacggtcagg tcgtcggtgt
    43801 gctggcagcg cgcgagcacc agcgaccacg cgccgtggac gagggtgttc gcggtgaggc
    43861 ggtgccgctt ggcgaacgcg tgcacgtcct cggcgacgtc cgcgaggtcg agttccgccc
    43921 agtcgtaggg gatttcgccg gtcctcacgg ccggtggcgt gccgacgtcg agccgcggcg
    43981 gcggggtgta cccggcgagc tggtcgcgcc agtaccgccc ggcctcggcg ccgtcctgcc
    44041 gccgccacca ggcgacgtag tcgcggaacc ggccagccgg gggcaggccc ggctcgtgcc
    44101 cgtcgcagca ggcgcggtag gcccgcagga actcgcccat gatgatcccg accgaccagc
    44161 cgtccaggat caggtggtgc acgctcagca gctggtgcca ccggtcgtcg ccgacggcga
    44221 ggcagaggtc catcggtggc cgcgcttcga ggtcgaaccc gttcgcgcgc accgggcgga
    44281 ggtagtccgc gatccggtcc tgcccctcgg ccgcgccgag cccgcgcagg tccagttcgg
    44341 tgcgtggcag cccgatccgc cggtgcacgg tttgcaccgg tttcttgatg tcgttccagt
    44401 ggaacgtggt ccgcagcgcg gggtggcggt cgaccacgtg ctgccaggcg cgccagtagg
    44461 cgtcggtgtc gagtgcgccc tcgaactcca gcacggactg ctccaggtag gttccttcgc
    44521 ctggcgcgta aaggttttcg aagagcatgc cgtgctgcag cggggtcagg tcgtagacgt
    44581 cttcgatctc acgtgcgctc accggatcgt gctccgtaac tcgtcggcca gcgcggacag
    44641 gaacgcgcct cgctgggaat gcgggaagaa cgggctcacc acggcgccgc accgtcgccg
    44701 tgctcgccgc cggaaacgcg tgcggcggcg atcgcccgca gttgcatgtt cgtggtgccc
    44761 tcgtagatct tgccgatctt cgcgtcgcgg tagagcttct ccgccgggta ttcggtggag
    44821 tacccgttcc cgccgagggt ttccaccgcc tgcgaggcgg cgcgctcggc gacttccgcg
    44881 gcgaggaact tcgcggtcgc ggtggcggtc agccgcttcg cgagcgggat cgcgtccagc
    44941 accgcgatcg tgtggtacag gtaggtccgc gcggcgtcca gttcggcggt gagcctggcc
    45001 aaggggaact gcacgccctg gtaggagatg atcggttcgc cgaactggcg gcgctgctgc
    45061 gcgtagtcga acgccgcgtc cagcgcgccc tgggcgagcc cgatcatctg cgccgcgatg
    45121 ccgatcttgc cgatgttcag cgtctccatc gcgatgacgc gcccgttgtt cgcgccgccg
    45181 aggacgtttt ccttgcccac cagcacgtcg tcgaactcca ccgcgcaggt ggagctggcg
    45241 cggatgccga gcttcgaaat ccgctcgccg acccgcaccc ccggcgcgtc ggcgtccacg
    45301 aggaacgcgg tggcactgga gttcccgctc ttcgcgaaca ccacgaagag ccccgcctcg
    45361 gccgcgttcg tggtccagtg cttgtgcccg gtgagccgga acccggtgcc gtccgggacg
    45421 gcttcggtgg tcagcgcgaa ggcgtcgctg ccggagtccc gttcggacag tgcgtaggca
    45481 ccgaccgtgg aggtggcgag gcggggcagg taccgccgct tctggtcgcc gtcgccgtgc
    45541 cgtagcagcg cgctgatcac cagcgcgttc tggacgtcga cgaacaccgc gaccccgggg
    45601 tccacacggg acagctcctc gatcgcgacc gccgaggaca gcagatcgcc gccgtagccg
    45661 ccgtacgcct ccgggacctc gatgcccatc aggccctcgg cgaacagcgt ctgcacgagg
    45721 ccgtcgtcca tccgctgcgc ggtgtccatc ttggacacca gcgggcgcac ggcccggttc
    45781 gcgaactcgc ggatctccgc gcgccgggcg ggatcgggct cgactggact gctcaatgga
    45841 actccccgga aacttcggcg aacacggcgg ccaggtcttc gtcgtccacg tcggcgagcg
    45901 ggaagtcgcc ggtgtcgacg tggatctcct cgtgcccgcg gcaccgctgc ccgacccggc
    45961 gcaccgcgtc cgcgaaatcg gtggaggtcg ccggggcgtc tccggtccac gccacgacga
    46021 ggccgccgtc ggcgatcgcc caggtgagct ccgcggccgc gcgcccggcc ggttcccagt
    46081 gcggccacgc gggcacgggg cacggaaccg agccgagcga gcgcaccagc acgtcgggag
    46141 agtgcaccgc gggcgcctcc accgcggacc ggtagcggcg cttgacttcg ggcagctccg
    46201 tgcccggctc gacgggcccg atctcggcga tgccgcccag cgcgccgacg gccgtcggct
    46261 gctctcgccg gtcgtgttcg aagtggacgg tcgagccggt tccgccgagc aggtcgaggc
    46321 aggcggcgag aaccacctcc tcggccgaca tccggtaggt ctcttcggcg gcggtcagga
    46381 tcgtcgcggt ttcctcggcg ccgagcgtca cccgcgccgg tgcggcctcg gtggcgccgg
    46441 tcagcccggc cagttcgccg agcagcgcgc cccagctcct gccatcggcg accagttcgt
    46501 gcgccaggca caccaggtac ctggtgtcgt ggaggtcgaa caccgcgaac ttgaccaggc
    46561 cgccctcacg gggatccagc tcctcgcgca tctcgtcgac catctgccgc atcgcgccgc
    46621 gctgccggtc ctcccgcagc acgcggaggt cgatctccgg tacgtaggtc ccggcctcgc
    46681 cgatccgctg gacccagtcc tcgccgtccc gctcgaaacg cccgcgcagc gcgggatgcc
    46741 tgcgtagcaa tgcctctatc cactcaggac agacaaagaa gtccgcgtcc accgggagtt
    46801 ccacccagtt cgcggtgccg cccggcttgg cgccgtcgag cagcgcgcgc tgcgacggcg
    46861 tcagctccac cgcgtctccc gcgccgtcga gactcgtcgc gcgcgcttcg atgatcgcgg
    46921 ccgcgtcggc gatggtctcc gcttcgaaca ggtccgccag cacgagctgc acgccctggt
    46981 caccggcgcg cgccgcgatc tgcaccgcgg tgatcgaatc cccgccgact tcgaagaagc
    47041 tggcgcgggc gtcgatgtgc tcgaccccga gtacctccgc ggcgatggcg gcgagccgga
    47101 ccgccagctc ggacagcggt gcgtcggccg tggtcgtttc gggtgttgtg gtggtggggt
    47161 gggggaggtg gttgcggttg attttgccgt tgggggtgag ggggaggtgg gtgaggatgg
    47221 tggtggttgt ggggtgcatg taggtgggga gggtttgggt gaggtggtgg tgggtttggg
    47281 tgcggagttg ttcgggggtg agggtggtgt gggggtgggg gtagaggtag gcgtggagtt
    47341 gtttgtggtg tgggggtccg gtggtggtgg cgatggcggt gtggatgtcg gggtgggtgg
    47401 tgagggtggt ttcgatttcg ccgagttcga tgcggtggcc gttgattttg acttgggtgt
    47461 cggtgcggcc gaggaattcg agggtgccgt cggggtggcg gcgggcgagg tcgccggttt
    47521 tgtagaggcg ggtgccggtg gtggggtggg tgaggaaggc ggcgtgggtt ttgccggggt
    47581 cgttgtggta gccggtggcc aggccgtcac cggagatgta gaggtcgccg gtggtgtgga
    47641 tggggcaggg ctggagttgg gtgtcgagga cgtggagttg ctggttggcc agcggagtgc
    47701 cgtacggaat cgaggtccat tcgggatcca gtgcggtgat ggggtggtag accgaccaga
    47761 tcgcggcctc ggtggcgccc ccgaggctgt agaggtcgat gtcggggtgg gtagcccaca
    47821 agttgtccgg tagcgcgagg gggatccagt cgccggagag catcaccaac cgcaacgacg
    47881 tggcgggtgt tccggtgggg aggtgttcgg tgtacatggt catcaacgcc ggaaccgaat
    47941 tccacaccgt gatgtcgtga gtggtgatca gctcgtgcca gtgcgcggga tcccgcccgg
    48001 tcgcgggcaa cacgagactg cctccggcgc cgaggacacc gaagacatcc cacaccgaca
    48061 ggtcgaaact caacgaggac aacgccaacg cccgatccgc cgacgtgacc ccgaaccggg
    48121 cgttgatgtc cagacacgtg ttggacgccg cccggtgcgt gatcgccaca cccttcggca
    48181 gaccggtgga gccggaggtg tagatgatgt aggcaagatc gtccaactgc gacacttgct
    48241 ctggtgtcgc atcccgagtc gcctcagcga gatcgacggg tgcggtgtcg agcagcgcca
    48301 cacgggtgtt gtcgggccag tccagggttt cccgggcttc ggtggtgagg atcaggcggg
    48361 caccggcatg cgtggccatg tggtgacggc gtgcggtggg gagttcgggg tcgatgggga
    48421 cgtagacgcc accggcgagc aggaccgcga ccacggcggt gatctgggcg gcggttttgt
    48481 ccatcgacac cgccaccacc tgtcccggtc cgacaccgag cgaccgcaac gtccgggcgg
    48541 tccggcaggc gcggacatac agttccccga acgtggtcca ttccccgtcg gcgaacaccg
    48601 cccgcgccga gggatccgcc aacgcacact ccaccaacgg accatgcaac agctgaacat
    48661 cgatcggcgc cgcggtgtca ttgaccgact cgatcacctc ccgctgccac cccggcaaca
    48721 ccgagtccac accggactcc caccccgaat ccccaccagc caacaactcc aacaccccgc
    48781 aatacgcggc aaacatctcc tccaccacac ccgccgcgaa caacccctcc acggcgggcc
    48841 agctcaggta cagcccgtcg gacacctcca gcaccccggc gtccagccag acctgcgggg
    48901 tctggatgac ctcgtaggtc agcccgccga tccagtcgac catcgagcgc tcggtttcgc
    48961 tttcgtcgac cagggtgctg gtgtagacga tcggcatcac cgacccgctc gtcccgccgc
    49021 gggcgcgggc gagttcgcgc aggacgtcga ccccgttgac gtaccggtgg tcgaggtcct
    49081 cccagctctg cgcctggatc gcccgcgcga tggcgccgag ggtgccgtgc tcggcgaggt
    49141 cgaccggcac caggttgaac gacgcgaacc cgccgaccag cccgccgacg tcctcgtgca
    49201 ccgggagccg gttgttggtg gtgacgttca gggtgaactt ctccgacgtg ctccacgtac
    49261 ccagtacgag cgcgtaggcg gccagcagca ccgcggacgg cgtgacgccg tacttgccgg
    49321 cgcgttcctt gatgctctcc cactgcgcga ccggaagggt gcggctgcac ggcacgaacc
    49381 ggggttcggt gatggtgtcc ggggcggtcg ccagcggcag ttccggcgcg ggcggcagat
    49441 cacgcaccct gtcccgccag taggcgagag aacgttggta cagcgcgctt tccttgagct
    49501 tcccgatcgc catcaggtag tcgcggaagg tgatccgcaa cggggtcagt tcggcggacg
    49561 ggtcctcgta gagcgtgcgc cagtcccgca gcatgacccg cacgctgccc atgtcggaca
    49621 ccatcaggtc gaacccgagg aacaccctcg tcagcccgcc cggcagcagg gcggcgcgga
    49681 tgttgaacag cggccactcg tcgccgggcc gtacctcgtg ggacatccgc tcgcgcacca
    49741 gcgccagctc ctccgccgcc cggtccgccg gggtggtgcg caggtcgagc acgtcgatct
    49801 cgtacggacc ggcgtcggcg aggatgcgct gggtgccgtc cgaggtgatg atcgcgcgga
    49861 gcatgtcgtg cctggcgagg atccggttga aggaaccgcc cagcctgccg aggtcgatgc
    49921 ggtcgtcttc gacctcccag tagatgtggg cggcgacgtt gccgacgctg aagttcgcgg
    49981 accggccgat ccactgcgcc tgctggattt cgctcaacgg gaacggttcg taccgcgcgg
    50041 ccggatcggg caccgcgacc gggagccgtt cgcgctccga cggcgcgccg cccgcctcga
    50101 ccaccagcgc ggccatcgct tccaccgtgg gtgccgcgat caggtcacgc agcggaacgt
    50161 ccacggcgaa ctcggcgcgg accccggcga cgatcttcgt ggcgagcagg gagtggccgc
    50221 ccagttcgat gaagttgtcg tggataccga tcgggccgac cccgatcagg tcctgccaga
    50281 tccgcgcgat ccgttgctgc gcctcggttt ccggtgccgc gtacgcggtg agcagatccg
    50341 ggcgagagcc gccgctctgc tcgtcctcgg tttcttcttc cacagtggac acgatcgcgg
    50401 agtcgagcga gcgggtgggg gtttcgccac cggccggtgc gccgatccag taccgcttgc
    50461 ggtcgaacgc gtacggcggc aggctgagca ggcggcggtg ctcgccctcg tgcatcgccg
    50521 cccagtccac ttcgaccccg gtcagccaga gccgcccgac ggcgtcgagc aggaaccggg
    50581 tgtcggagtg ctcctccgcg ggcgcgcgca tcgcgttgac cagtacgtgc ccgcgcaggt
    50641 ccgggtccat tctggacaga ctgcccagcg tgtgccccgg cccggcctcc agcagcaccg
    50701 tgccgggatc ggcggccagc ttccgcaggc aggcgtggaa ccgcacgggg tcgcggacct
    50761 gaccggccca gtacgccggg tcggtcgcct gcgccgcggt gatccagtcg ccggaacggt
    50821 tggacaggaa cggtatcgcc ggtgcggaca gcgggatccg ggacagcgct tcggtcagcg
    50881 gtgcgacggc ggggtccatc atcgcggtgt ggaaggcgtg cgaggtgtgc agcctgccga
    50941 agtcgatccc gcgctccctc agcagttccg cgaactcgtc gatcgcgtcg tgcgtcccgg
    51001 cgaccgcgca ctggccgggc gcgttgatcg cggcgatctc caccgacggg accagaacct
    51061 cgcgcaaatc atcctcggac agcgcgacgg tcagcatcgc gccgctcggc tgctgctgca
    51121 tgagctttcc gcgaacggcc accatgtgca gcgcgtccgg caatgtgaag acaccggcga
    51181 ggcaggcggc gacgacctca ccgacgctgt gcccgagcat cgccttcggc ttcccgcacc
    51241 acgactccag cgtcttcgcc agcgcgtatt cgacggtgaa cagcgctggc tgggcgagtt
    51301 ccgtccgttc gatgcgatcg ccgccgtcct ccgcgtaaag cacgtcgcgc aggtccagcc
    51361 cgaggtgcgg gcgcagcagc tccgcgcatt cgtcgacccc ggcgcggaaa acgggttcgt
    51421 cgcggtagag gtcccggccc atggcggggt actgggtccc ctgcccgggg aacagccacg
    51481 cgacctccgg cgcgtcaccg gcctgcctgc tgagcacgcg ctgcggatcc cggttttcga
    51541 tcgcctcggc cgcgtcctcg gcactggagc acagcacgac cctgcggtgg ggcagtgcgg
    51601 tacgggtggt ctgcaggctg aacgcggtgt cggcgagcgg ttccccgctt tcccgcagtt
    51661 cccggccgat ccggccggtc atcgcgtcga gcgcaccggc cgaccgagcg gacagcacga
    51721 tcgcctgcac cggtttgccc ggcgtggacc gggttgcggc gggcgcttcc tcgagcacgc
    51781 aatgggcgtt cgtaccgccg aaaccgaacg agctgacgcc gatccggcgc ggtgtcccgg
    51841 tcgcctgcca cggccgcagt tcggtgttca cgaagaacgg cgtggcgtcg aagccgatgt
    51901 ccgggttctc ctgctcgaag ttcaggctcg gcgcgatttc ccggtgctgc aactggagga
    51961 tcgccttgat cagtgccgcg atcccggccg cgctgtcgag gtggccgata ttggacttga
    52021 ccgagccgat cgggcagcca ccggcgtggt acgggccgaa gaccttggtg agcgcggcga
    52081 tctcgatcgg gtcgccgagc gccgtgccgg tgccgtgcgc ctcgatcgcg ccgatcgtgc
    52141 cggggtcgat ccccgcggcg ccgagcgcgg cggcgaccac cttcgcctgg ccggtgctgc
    52201 ccggcgcggt gtagccgacc ttgcgggcgc cgtcgttgtt gaccgcggag cccttgatca
    52261 ccgcgtcgat ccggtcgccg tcggcgagcg cgtcgtccaa gcgcttcagc accacgatcc
    52321 cggcgccgtt gccgccgatg gtgccgctcg ccttcgcgtc gaacgggcgg cagtgcccgt
    52381 cggcggacag gatcatgccc tcctggtagc ggtatccgtg ctgcggcagg cggatcgtcg
    52441 cgccaccggc gagcgcgacg tcgcagtcgt aggacagcag cgactggcag gcgaggtgca
    52501 cggcgaccat cgaggtcgag cacgcggtct gcacgctgac cgcgggaccg tcgaggtcga
    52561 gcttgtaggc gatccggctc gccaggtagt ccttgtcgtt cgcgatcagc agctcgaacc
    52621 cgtcgggcga ggtgtccatc gcgcggccgg ggagcaggtt cgccagcagg taggtcgaca
    52681 tgctgctgcc cgcgaagacg ccgaccgtca cgtcgtcgcc gaagcgccgc tgcccggcgt
    52741 cttccagtgc ctgccaagcg gtttcgagga gcacgcgctg ctgcgggtcg aggaccgtgg
    52801 cgtcacgggc gctgaacccg aagaagcccg cgtcgaacag gtcgatgtcg tcgagcgcgc
    52861 cgaaagcctt gacgtaggcc ggatcgtcga tcagctcgtc ggctaccccc gcggcgcgca
    52921 gtgcttcgga atcgaagaag gtcaccgatt ccttgccctc gcgcaggttc tgccagtact
    52981 gccgctggtc gttcgccccg gggaaccggc aggccttccc gatgatcgcg atctcggtgc
    53041 cgtcgttcgt ggaagtcatg ccagtgcccc gtcggtggtc gtggtggtgg tctgcggacg
    53101 cctgcgggca cgccggtcgc gggcgcgcgc gaacgtcgcg gccaccgcgt cctcggtcgt
    53161 gtcggcaccg ccgaggtggg cggcgaggtg ccggatgctc gggttttcga acaggtccgt
    53221 caacgcgaag tcgcgaccga ggccgtcgcg gagttcgcgg tgcaccttga ccatgacgac
    53281 cgagtcgagg ccgaggtcga agaagttcgc ggtcacgctg atccggcgcg aatccaggat
    53341 ttttccgacc aggacgagga tgcgcttttc cagctggctg gccggttctt cggtggtcgc
    53401 gggtgttgtg gtggtggggt gggggaggtg gttgcggttg attttgccgt tgggggtgag
    53461 ggggaggtgg gtgaggatgg tggtggttgt ggggtgcatg taggtgggga ggtggtgggt
    53521 gaggtggtgg tgggtttggg tgcggagttg ttcgggggtg agggtggtgt gggggtgggg
    53581 gtagaggtag gcgtggagtt gtttgtggtg tgggggtccg gtggtggtgg cgatggcggt
    53641 gtggatgtcg gggtgggtgg tgagggtggt ttcgatttcg ccgagttcga tgcggtggcc
    53701 gttgattttg acttgggtgt cggtgcggcc gaggaattcg agggtgccgt cggggtggcg
    53761 gcgggcgagg tcgccggttt tgtagaggcg ggtgccggtg gtggggtggg tgaggaaggc
    53821 ggcgtgggtt ttgccggggt cgttgtggta gccggtggcc aggccgtcac cggagatgta
    53881 gaggtcgccg gtggtgtgga tggggcaggg ctggagttgg gtgtcgagga cgtggagttg
    53941 ctggttggcc agcggagtgc cgtacggaat cgaggtccat tcgggatcca gtgcggtgat
    54001 ggggtggtag accgaccaga tcgcggcctc ggtggcgccc ccgaggctgt agaggtcgat
    54061 gtcggggtgg gtagcccaca agttgtccgg tagcgcgagg gggatccagt cgccggagag
    54121 catcaccaac cgcaacgacg tggcgggtgt tccggtgggg aggtgttcgg tgtacatggt
    54181 catcaacgcc ggaaccgaat tccacaccgt gatgtcgtga gtggtgatca gctcgtgcca
    54241 gtgcgcggga tcccgcccgg tcgcgggcaa cacgagactg cctccggcgc cgaggacacc
    54301 gaagacatcc cacaccgaca ggtcgaaact caacgaggac aacgccaacg cccgatccgc
    54361 cgacgtgacc ccgaaccggg cgttgatgtc cagacacgtg ttggacgccg cccggtgcgt
    54421 gatcgccaca cccttcggca gaccggtgga gccggaggtg tagatgatgt aggcaagatc
    54481 gtccaactgc gacacttgct ctggtgtcgc atcccgagtc gcctcagcga gatcgacggg
    54541 tgcggtgtcg agcagcgcca cacgggtgtt gtcgggccag tccagggttt cccgggcttc
    54601 ggtggtgagg atcaggcggg caccggcatg cgtggccatg tggtgacggc gtgcggtggg
    54661 gagttcgggg tcgatgggga cgtagacgcc accggcgagc aggaccgcga ccacggcggt
    54721 gatctgggcg gcggttttgt ccatcgacac cgccaccacc tgtcccggtc cgacaccgag
    54781 cgaccgcaac gtccgggcgg tccggcaggc gcggacatac agttccccga acgtggtcca
    54841 ttccccgtcg gcgaacaccg cccgcgccga gggatccgcc aacgcacact ccaccaacgg
    54901 accatgcaac agctgaacat cgatcggcgc cgcggtgtca ttgaccgact cgatcacctc
    54961 acgctgccac cccggcaaca ccgagtccac accggactcc caccccgaat ccccaccagc
    55021 caacaactcc aacacaccgc aatacgccgc gaacatctcc tccaccacac ccaccgggaa
    55081 caacccctcc acggtgtccc agttgaagtg cagctcaccg tccttttcgt acgtctggtt
    55141 gtccacccag acctgcggtg tctgcgaaat cgcgtaaccg ggctcgccga tccattcgcc
    55201 ggtcaggtac ccgcggccct gcccgcgtcc gctggcgaag acgaccgggg cgaccgcgct
    55261 cgtcgccgcg ccgtcgcgca gcgccagttc gcgcagcacc tcgataccgc tgaacctgcg
    55321 atggtccata tcggacagaa gctgccgctg gattcggatg gccagctcgg cgatcccgtg
    55381 gtcaccgcgc gcgtcgacgg ccagcggcag gatcgtggtg aagtcgccga tcacctcgtc
    55441 gatccggtga tgcagcggct gccggttgaa catcgggatg ttcagcagga accgctccga
    55501 gccgctccag gtccgcagca ccacggcgta cgcggccagc agtaccgctg acggggtgac
    55561 gccgtacttc ccggcccggt tggtgatccg cgtccaagta ccggcgtcga gctgggattc
    55621 gatgcggcgg aaccgggatt tcgcgttctt cgcccgctcg acgaccggca gccgcggtgc
    55681 ccccggcatc gtgtcgatgc gatccatcca gtagtcgcgc gcccgccggt actcggcgtc
    55741 gtcggcatcc cgctcggtgg cgatcaggta gtcgcgaaag gacacttcgc cggtcaacgg
    55801 cgccagttcc ttgccgttgt agagcagttc ccagtcgtcg tagaagatct ggatgctgcg
    55861 gacgtcggcg atcagcaggt ccaccccgat gtgcacgcgg accttcgact tcgtgagccg
    55921 gctgatcctg acctcgaaca gcgggccgtc ttccagcggc atgacgtgat gcgacatcgc
    55981 ggcgcgggtc cggtcgagcc gctcggccgc cgcggtcccg tccaggtgcc ggaggtcgtc
    56041 gacggtgacc ggcaccgcgt ggtcccggag cacccgctgc gtcccgtcgg cggagacggt
    56101 ggcgtgcagc atttcgtgcc gctgcacgag tttctccaac gagccgagga accggtcgac
    56161 gtcgagggtc tcggagtcga actcgcggta gtagtgtgtc gccactccgc cgagttcgta
    56221 gacgtcgtcg cggccggtga cgtacgcctg ctggaggccg gtgagcggga acggttcgta
    56281 ccgcgcggcg ggatcgggca ccacgacggg tgccggtgcg gggctcgcgg tgtccatttc
    56341 ggactgtgcg aggatcttcg cggtcacttc ccgcgcggag gcgagcagca gttcgtccag
    56401 cgcgagccgg acgccggtct cctgcgccag ccggtggcgc accagcatgc cgcgcaagga
    56461 gtccagcccc agtccggcga gggtggcatc ggaggccagc acgtcctccg gcgcatcgcc
    56521 gccgagcacg tcttcgagca ggcgccgcac caccacggga accgcggccg tacccacggt
    56581 ggcatcggct gcgggcacgg tgagtccgcc cggcacgctc gtggccagcg gggcgagcct
    56641 gccttcgagg tacgcctcgc ggcaggcggc gcggcggatc ttgcccgcgt tcgtggtggg
    56701 cacggccgag gcggccacga cgagcacctc ggcgtcgacc cggtggttcg cggtgaccgc
    56761 cgcgcgcagg tccccggcga gccgctcggc gtcgagttct tcgggggacc tcacggcctg
    56821 cacgaggacg agccgctcgc tctcctcgcc ctccaccgcg aacgccgcgg ccggtgccgc
    56881 cgtggtcgcc gggtgcaccc cggccgcggt ggtttcgatg tcctgggggt acaggttccg
    56941 gccgcggatg atcagcagtt ccttcagccg tccgcagacg aacagctcgc cgtcgtggcg
    57001 gaaaccgagg tcaccggtgc ggacgaacgg gccctcgccg ttcgcgaggc tcgcgtcgaa
    57061 cacggccgcg gtttcccgtg gccgccgcca gtaccccggc gcggtgaacg ggccctgcgc
    57121 ccagatttcg ccgacccggc ccggtgccac ctcggtacgg gtctcggggt cgacgacccg
    57181 gatcgtggtc gcgggaccgg gatcgccgca gctgaccaga tcgatcgcgg tgtcatcgga
    57241 ttcgggcacg atgcgggcgg tgtgcgcctc cagcgccgcg cggtccagtg cgagggagcc
    57301 gatgtccccg gcgcgcctgc cgctgaccag gagcgtggtt tcggtgagcc cgtagaccga
    57361 gaacatgctg tcgcgggcga atcctcgcgc gccgaatcgc gcggtgaagc gttcgagcgt
    57421 gttcttccgg atccgttccc cggcgaccag tgccgagtgc cagttgtcca gatcgagccc
    57481 ggcgaactct tcggcggtga cgaaatcggt gcaccggtcg taaacgaagt tgggcccgcc
    57541 gccgaatacc ggagaattcg ccgcgctgat cgcttccagc cagctcgccg gccgcgccac
    57601 cacatcctcg gtgcgcagga ccgaacagtc gccgccgagg tactgggaaa gcagcaaatg
    57661 tccgatcagc ccgattccgt ggtgcaccgg aacccagttg acgacggtgg caccggccgg
    57721 gatcccggtc atccgcacca ttttccggat acccgcgaga atgctggcgt gcgagttcag
    57781 cacacccttg gggtcccctg tggaccccga ggtgtacagc agcatcgcga ggtcttcggg
    57841 cgcgcaccga gcgggtgcct ggtccgcggc cgacgggcgc accagttcgt ccacggcgag
    57901 ccaggcgatc gcgtccccgc ccgcggattg ccagcgccgc ttggcttccg cggcgacagc
    57961 ggtactggtc aggatcgcct cggcgcccgc gtcgcgcccc accgcggcgg ccatcgcgct
    58021 ggacaccggg gtgccagcgt agccgagcgg gaccgcgcac ctgcccgcgt acaggcagcc
    58081 acacaccgcg atgacgtaat cacgtgccga cggcgtgaga acgagaattc gggcaccggg
    58141 cgcactggcg gtccgtaatg cttcggctac cgccagcgcg cgaatgtgca agtcccgggt
    58201 gctcagcgaa tcggcggcag gggaatccgg gccgtcggcg aacgagaatg cggtgcggtc
    58261 cggttcttcg ccggcgttcc gcgcgagcac atcgatgatc gttggagcgt tttcggcgcg
    58321 tgcgggcatg atcctcgatg cctttcctcc gggttgagca tcgagtcttc atggcgggtg
    58381 ggcggcgcga aagatccgtc ggccggtcca ggcgggcgct cgaccggcat agctgaatgg
    58441 ctacgttgac agccgggtgc gggtggcccc aggttgggcc cttgatccgt ttcccttccc
    58501 cgctgtgtcg ccgccggacg gcttgacaca gttcgtatgg taccgagaca ctatgtatcg
    58561 agcaaggcca agttgttcgg cacagcacca ccgatccgtt ccctgcgaca agttcaggtg
    58621 tgcatatgac agcgacatcg gcagcgccgg tcgtgaccgc gaccgagcga acaccggcca
    58681 tccgcgcggc cgggctgaag aagcgcttcg gtgagaagtg ggccgtcgac ggggtcgacc
    58741 tcaccgtgcc gcccggtcag atctacgcgt tcctcggacc caacggggcg gggaagtcca
    58801 cttgcgtccg tatgatgtgc acgctgctcg cgccgacgga gggcaccgtg agcgtgctcg
    58861 ggcacgacac ggtgcgcaac cagcttgacg tccggctgcg cgtcggcgtc gcgctgcagg
    58921 cgaccgcgct cgacgacaag cagaccggtc tcgaacagct ccgcctccag ggccggttct
    58981 acgggctcgg caagaagacg atcggcaagc gggtcggcga gctgaccgag ctgatcgatc
    59041 tcggcgacgc ggtgcgggac cgggtgggca cctactccgg cgggatgcgc cgcaggctgg
    59101 acctcgcggt cgcgctcatc cacaacccga gggtgctctt cctcgacgag ccgaccaccg
    59161 ggatggaccc ggccagccgg atcaagctct gggccgaggt caaccggctc aaccgcgaac
    59221 tcggcacgac catcttcatg accacccagt acctggagga ggccgatcag ctcgccgagc
    59281 gcgtcggcat catcaacgag ggcaaggtgg tcgccgaggg cagcccggag gagctcaagc
    59341 ggtccatcgg caaggacctc atcgtcgcca cgacgagcga cgggacttcc gccgaaatcg
    59401 cgctgcgcgg cctgccggtg gtgcagcgcg tcgacgtgaa cggcgaagag gtcacgatcg
    59461 ccgtcgaaga cggtccgacc gcgatcagcc cggtcgccct cgcgctggcc gaaaacgccg
    59521 tgaccgtacg gaatctcgtc ctgcgccgcc cgacgctgga cgacgtgttc ctttccatca
    59581 ccgggcagca catgtccgaa gaagacgcac tcgcggacgc ggggaaggtg acgcaatgac
    59641 cgctaccacg gaggccacga ccgcggtccg ggcggagacc gaggagctgg tcggcagacc
    59701 ggccggtttc ctgcgggacc tggtgagcgt ttccggccga tcgctccgcc agctggtgcg
    59761 cgagccggag accctcatcc cgccgatgct catctcggtc ttcttcttca ccgttttcgt
    59821 cggtgcgctg gaaaagatcg gaaacctcgg cggtaccgcg gacttccgcg cgttccagtt
    59881 cccggtggcg atcgtcatcg cgtcgacggg gacgaccagg gcgacctcgt tggtgcagga
    59941 catcaacaac gggtacttcg accgcctgct catcgcgccg acgaaccggc tttcgctgct
    60001 gctcggcctg atggtcgcgg acctggtgac cgtggtggtg ctgtgtatcc ccacggtggt
    60061 gctcgggttc gtgttcggcg tcggcttcgc gtcgggtgtg ctgggcgtgc tcgtgttcat
    60121 cgcgatcgcc gcgctgtggg ggctggcgtt cgccgcgatt ccctatgcca tcgcgttgcg
    60181 caccggcaac gcgaccgtgg tcgcgcagag ctcgctgctg ttcttcccgt tcgtgttcct
    60241 gacgaccacg ctcatgccgc tggaccgcct cagcggatgg ctcgcggccg tggcgcacgt
    60301 gaacccggtg acctacctgc tggccgcgct ccggtccctg ctcaccgacg gatggaacgg
    60361 gccgacgttg ctgctgggcg tcggcgtcgt gctcgccgtc gccgtcgtga cgttcagcat
    60421 cgccctgctc gcgctccggg gacgggtgtc gcgatcctga actcgtcggg tccccttccc
    60481 cctgggacac cggcggcccg acggcatgtg cggtgcgcac cgcacatgcc ggacggggct
    60541 cgccgcggcg cggaaccccg gaacgcgaag gtgggagtgt cgctcagcga ggtcctccgg
    60601 tgctcgtggc acccgatcgt cctcagtgaa cagacactcc cacccgaaag cgatgtctcg
    60661 tgtggccccc agaccccagt tcagttcgtg gtacttcagg caatgatgct tcaggcaatg
    60721 atgttgtcgc gcaaggcgac cgcgaccgcg agtgtcctgt tgggacaatt cagcttcgcg
    60781 agcacgttgg cgacgaggcg tttggccccg tgctgtgaaa tgcgcagttg tttggcgatt
    60841 tgcttgttgc tgagcccgtc gaccagtagg cgcagcgcct gctcttcgcg cggggtgagg
    60901 ctggccagtc cgtggcgctg ggcggtcgac ccggtgcgca gcctggtcag catgcgaccg
    60961 gccagcaccg acgggatgac gatctcgccg gagaccactt cccgcagcgc gcggtccaat
    61021 gagtccggtg tgatctggtg cagcagcagg aatccgttcg ccgggatgct cgacaccgcg
    61081 tcgaacagct ccgggttctg gatcagcagg agcagcagga ccttgctccc cgccgctctt
    61141 gcccgttcgg cgtacaactg gacggtatcg gtgttcagcc cgttgcaccc cagcaccacg
    61201 acatcggggc accgatggcc cggtgcgccc gcggtgcggt tggcgtcctc gaggtacttc
    61261 cattctgtta ttgagtatga attcgtggat ttgagcatag aggtcaatcc acgtcgaatt
    61321 acatctcctt cgacgaaaac ggcgacggag gattgtcttt cgtgactttt cggcaggctt
    61381 gctattcgtt cttcgggcat ttaatccccc ttcgtgaccc gcagcagcgg agaaggcgcg
    61441 ccgcaggtgg gaaaatatca ccatgcgtgc gctgtgtgca agagatcaca cgatccttga
    61501 tggaggctta agattgtaac cgggcgagca cccaaatggt ctattgtgga cttggggcgg
    61561 agatcggcat cccgtatgtc tgttttcttc cggtgtcgtc actggctatc gcccctggtg
    61621 gagcacgcca tgggacaaaa gtagccaaat tgtgtccatg gcttcgtccg cggagagggc
    61681 gccgaccgta atgtcctctt gcatactcgc caccattttg aacacgagtt tgccatgtcg
    61741 ttgtgaatcc agttccttac gcatgcggcc ggcagcaatt ccgtcgcgca gggtagcgat
    61801 aatggctttg tgcaaccggg tcatctcttc ccgtagcgtt gccatggcct tggcggagag
    61861 atcggccttg tcgaggctgg cccagccgac ccggtgctgg cggctggcga aatagtcgag
    61921 caacgcgcgc acgcacgcac gaagctgttc cagtggatcc tcgtgctcgg cgatgacttc
    61981 gtcgagcctg gcctcgcaga cgtcgatctc gcgccccacg tgggccagca gtgccgactc
    62041 gacatcgggg aagtacttgt acagggtcgc cctgccgacg ccggcgtgct gcgccagctt
    62101 ggccatcgac gtcttggtga cgccgtcgtc ggcgatcagt tcgatcgccg cgtcgatgat
    62161 ctgctcgcgg taccgggcct tgtgcgtctc gacggcggat tgccacgcct gggacatctg
    62221 gttcccctct ctccagcagc gcgaacgtcc agggtgagac gatgtgtctt gactcgggtc
    62281 cgattgtatc gccataatcg gcgcagcgac gaatcccgga ccgtgcggcc cgggatgccc
    62341 tcgcgcgcac gtgctctgtc caaaaaggac ggcgtgggcg cggttttcgc gcgccgtcga
    62401 tgcgcgagcc cgtcagctca gcagcagcat gcggtcccag ttccggttcc cgtcaccggg
    62461 ttctccggtc agcagggcgt tgagcgcgca gccgaccccg gccgcgccgt ccagcagccc
    62521 cggccggtgg cacacctggt agcccggtcc gtcgtggacg ggggcgacga cgaggaacgg
    62581 cgcgtcgaag tcgacgaagt ccagcagcct ggccgcgatc cgtcgcgcga gcgccagcag
    62641 ttcgccgtcc tgttcggcca ccgcgagccg gtgcacgacc tgcagccgtc ccgcgtgccc
    62701 gtggcacagg tacggatcgg tcaccagcgc gtcgtgcgac gacgcggcac gcaccgcggt
    62761 cacggcgagt tcgcgccagg ctccccggtc caggaccgtg cccgcgcggt gcagcgcggc
    62821 cgcgatgccg tgcacgccgt agcaccaccc gtcccggggc cgcaccccgt cttccggcag
    62881 gcgatcgccc ggcggaacgc gcggcaccca gaacggtccg tcctgatcgg acgacgcgtt
    62941 cccgatcagc cacccgcaca gtgaaccgat cgcgtcgagc tgcccgtcca ccagcacacc
    63001 acgctgcgcg gcaagggaaa gcagggcgat cggcccggcg atgccgtgcg ccatgccggt
    63061 gttggccgcg ccgatcgggt agtagcggcg ctcctcggcc agcgggagct gctccggggc
    63121 ggtccaccat cctggcaccc ggtggcccgc cgcgtcgcgg gtttcgctca accgcaccaa
    63181 gaaccggagc gtggccagca ccgcggattc gaccgccggt gaattctcct cgtcggcgct
    63241 cagcgcgtcg agcaggatcc tgcccacccc agtgatcccg gtgatcacgt cgtacgttcc
    63301 ttcggcgaca ccggtttccg gtgcgctcgc cgcttcgatc ctggttgcct gatttccggc
    63361 ggcccaggtc agcagggacg atctcaggct cgcgtagtca ccggtgcgcg cgccgcaggt
    63421 ctgcgcggcg aacgcgatcg acgcgggccc gaggtacagg cccagggcgg ggtggtcgcc
    63481 cacggcccgc atcgaggcga gcaggtgcgc gtgcgcggcc gccgcgtgcc gcccgccgga
    63541 ttcggcgaac tgcccgtaga acaccgccag cccgggatgg ccgttcgcca ggccggtggg
    63601 gacccagccg ccgttctccg cggccagcac ctccgccgcg gtgcgcgaaa ccgctgtcgg
    63661 atcggcgaac cgatccgaca gcagcgtcac gaattccctg gcgcgctccg cggtggcacc
    63721 gcgccaggtg ccggtctcaa ccgtcacgca cagaggatga gggtcacggt gacgcagggg
    63781 gacgggcaca gcggggaggg ggtggtgacg ctttggaggg tgcccgtttg ggccgacgag
    63841 ggcacggcgg tcaccgccga aagctcctcg acgctggtga agatgtcgta gcccgctacc
    63901 agttccttgg tgttcatcgg tttcaccttt ctgccggtgc gctagcgcac agccccggga
    63961 ggtccgggga atccaggttg cgggcgggtg ccgccggatc gatgttcgct tcccgcagcg
    64021 cctcggcgac gcggccgatc ctgctgccgc cgccaggttc cgccgcgtgc cggaccagcc
    64081 cggtggcgag cgcgagcgcc cggtgctggc cgaagctcag cgcgcccatc ccaggccggg
    64141 ggtcggccgg ttcccacgcg atcgccacgc cgggtcggac ccgcttggcg aacgcggagg
    64201 tctcggtgcc gagaccgggg tggtcgtcga gcagctccgg caggtgcgcg acgaaatcga
    64261 tgctgtcggc gtcgaggtag acgaccatcg cgtcgcgcct cggcagcgcc tccggtccgg
    64321 aaaggacttt cgcgaggtgg ctcgcgccct tcgcgtgcaa cgcgtgcagg acggtccgcc
    64381 acaccgccgt catcgcgtcg agttccacca ggtgcaggta gacgcggagc accgggcccg
    64441 gtgcgcgcgt gccgtgccgc tgcgcggtga gaaagaaccc cggcgacacc gcgggtctca
    64501 cggtgctcac gtcgaggtcg accgtctccc cgcgccgcgg tggggcggtg ctcctgagcg
    64561 aaccgggttc ggccgcgacg cgcagcccgt cccgttcgac cacgaccgtg ccgtcttcgc
    64621 gaacgtcgag taccggcacg gtgatcgtgg tggtggtcct cggcaccgct tcggcgagtc
    64681 gtcgttccaa ggcgtggtcc cggtccgtac cgcgcgccgt cgccgcgatc gccccggtgt
    64741 gcgcgttccg gtagagctgg tgcccgagcg ctcgcacgag ttcgcgggcg ttggcgccgg
    64801 tcacctcgtc ctcgcccacg gttgccttgc gacacaaggg atccacgcgg acctggggaa
    64861 gggtcgcgac caggtcgggg cagagcgcgt ccccggtcac gcggcgagcc cgagcgcgcg
    64921 ggtgaaccgg tcggggtcgg cgaggatggt cctgccgatc ccggcaccgg cgcgctcgac
    64981 cgcgccaagg gccggaaggc gttccgccgc ggcgaccatc cggtctagca gatgccagcc
    65041 cgcgaaggcg cagcacctcg cggcgaaccg gtcgtcgcga gggccgcgca ccgcctggta
    65101 cccggcgtag cacgcggcga cccacgggcg gaactcgtcg atcgccgcgg caccggcggc
    65161 gaggatctgt tcgtgcgtca gcgccgggtc gggcaggtcg gggtcgcccg cggcgggaat
    65221 ctcggtgacc gcgcggtgca gccattcgcc gatcagcgcg ccgaggtcgc gggcgggttc
    65281 ggcgagccgg aactcctccc agtcgatgac ggacagttcg ccgccgtgcc acagcacctg
    65341 gtccagccgg aggtcgcagt gcgccggttc gagcaccgtc gaggagtccc ggtcgcgcaa
    65401 ccggcggacc gcctcgagca gcacctcgtc gcgttgcatc agcgcccacg cctgcagcgc
    65461 ggcggcgctg gagttctcga acacccgcgc gggcagcgcg tcgagcgcct cacccggcgg
    65521 atagggcggg taggaggaat ccgttcccgg cggcagcggc gcggcgtgca gcgcgccgat
    65581 cgcctcgccg agcctgtgcg cgagatcctc gccgaactcc ccgtcaccgg cgagatcgcg
    65641 gccgctgcgg gcgtcccgca ccagttcgaa caccatcacc ccggtcgcct cgtccacgcc
    65701 gaggcagttc ggggcgtgga gaccggcgaa gtacccgtct tcgaaatacc gttggaacgc
    65761 catcgcccgc ccgagccggt ccgccgccgc ggcgccggac gaactggcca ccactttcac
    65821 gaagacgtcc tgccccgatt ccgtggtgcc cgcgtaactg gtgttgcggc cacggggcgc
    65881 gggcagtccg tcgtcgacga aacccccgat ccccagcgcg cggaggaccg cgtcgacatg
    65941 ctccggaggt tgctgcacgg caaccggcgc catcttgtat ccctccccag agattcccgg
    66001 acacgcgggc gatccgccat ggcgtgttca cgggatgcca aagatcttcg tggaggacac
    66061 cccgcgggtc aactgccaat ggacataacc gatcgggcat ggcccgacgg gtatgcccgc
    66121 acgggtgttc cgccgggacg ggaacggtgc cacgatgggg gatccgcctg tcggaggtgc
    66181 tcgaaatgcg cgtgctgacc acgatggcgg cgctgagcgc gctgctcgcg atcgcggcct
    66241 gcaaaccggg aacgcccgat gccggtggcg gcaggacctg ctcgacttcg gtgccccggc
    66301 cgcggatcac cgagcaggac aacggcaaga ccatctgcat ggggcgcaag gcacccctga
    66361 cggtgacctt gcacggcagc gccggtgatc cgtggcaggc ggtgtccgcg agcgggccgg
    66421 tgctgaccga gaccggcagg cccgcggtct ccggcgcggt caccaccgcc gcctaccagt
    66481 cgaaccgcgc gggcagcgga accgtttcgg cccaccggaa atcgggccgg ttcgagatca
    66541 ccgtcatcgt gcgcgactga gtcctgctca gagcatgccg ccggcggcga tcaggttctg
    66601 gccggtgatc caccggccgt cccggccggc cagcatggcc acgacgtcgg cgatgtcggc
    66661 gggctcggcc atccggccga gcggggtgag cgcggcgatc gcggcggtgg cctcgtccgg
    66721 cacggcgtcg ccgtgcaccg ggccggggga gacggtgttg acggtgatcc gccgcgggcc
    66781 gagctgacgg gcggccacct tggtgaactg ttcgacggcg gccttccccg cggcgtagac
    66841 ggggtcggtg aggctcggcc acgcggtcgc cgaactggag atgttgatca cccgaccgtc
    66901 ctggcgcaac cgcgggatcg cttgctgcag aacgaagaac gcccccttgg cgttcaccgc
    66961 catgacgtgg tcgtaccact gctcggtcac ttcgccgaac accttcgccg agccgatgcc
    67021 cgcgttgttg accaggacgt ccagctcggg cacggcctcg aacagccgct cgatctgcgc
    67081 cgcgtccgtc acgtccgcgc ggacggccgt ggccctgccg cccttgccgc ggacctcggc
    67141 caccacgtcg cgggccgcgg tttcgtcgct gtggtaggaa aagacgacgt ccgcgccgtc
    67201 ctcggcgagg cgcagcacga tcgcgcggcc gatgccccgc gaaccaccgg tgaccagtgc
    67261 ggtcctggtc atggctccac tccgttccgg ctgaccggca tgagcgcggc gagcggggcc
    67321 gccacttccg ccgcgtcgcc gaccacgacg acgacggcgc tgggcgggtt caggtagcgc
    67381 gccgcggctt cggtcaccgc gggcacgtcg gcgtcgacga gcctgctcgc gtgctcgccg
    67441 agccagtcaa ggcgcagccc ctgcgccgcg agctcggaga ccaggttcgc cagcccggac
    67501 tgcgtggaca tgctgagctg ccgcacgccg agcaggtact cccgcgcctg gtcgacctcc
    67561 gcggcgcgca ccggggtgca ggccatccgg ccgagctcgt agccgatctc cagcaccgcg
    67621 ggcgcggtga ccgcggtggc gacgtcggcc agcacggcga ccgcgcttcc cgcctgcgga
    67681 gagaccactg tggacttcgc ggagtacgtg tatcccttgt cctccctgag gttcgcggcc
    67741 agccgcgagg agaaaatgcc accgaagatc aggttcgcga ggtccagttc cgcgaagtcg
    67801 gcggcaccgg ggccggggca cggcagggcg agccgcaccg acgactgcac cgcgcccggt
    67861 gcgtccagca ggccgatcgg ggtgccgccg cggcaggcgg gcagcggccg gtgccggacc
    67921 ggttcgccgc caccggcgaa cccggacagc gcgcgttcgg ccgtgcgcaa ggcctgctgc
    67981 ggatcgaggt ccccggccag cacgaggcag gccgacgcgg cgcggacccg ttcggcgtgc
    68041 agggcgacga gatcggcggg ggtcaccgcg agcacgtcct ccggcgacgg ggtcgggcgc
    68101 gcgtagacgt ggtcgccgta gagccgccgg ttgagcgctt ccagcgcgcg atgcccctgc
    68161 tgcaccttga ccacccggag cgcgtccgcg aaccgcgcgg cccgctgcgc ggtctcgacc
    68221 tcgggatagc tggcggcggt gagcacctcg ccgagcaggt cgagcaggtc accgaggtgc
    68281 gccgccagcg cgctgccgag gaagagcaac cggtcggcgt cgacggtggc gctgaggctg
    68341 cctcccatgc gctgcaggcg tttcgccagc tccgcggtcg gcgtgcgcga ggtcgcggag
    68401 cacagcgaat cggcgagcag cgcgatggtc gccgagtccg cctccgcgca gggaatccgc
    68461 aggcgcattt ccaccagcgg gatcgacggc tgccgtaccg cgagcacggt cagcccggac
    68521 ggcagggtca cctcggccga ctccggcagc acgagcgcgc cgcgcggcag cagcgcggga
    68581 acgtccacat cggacagctg cccggtcatc gcgcggcccc cggcaggatt tcgacgacgg
    68641 cgcggtgcgc ttcgccgacc gtcgccgcag cggcggcgat ctcgtcgccg gtgagggagg
    68701 agagcaggcc gggcagttcg gcgatcaagg ccgcatcgcc ccgctgctgc tcgaagagcc
    68761 cgaacagctt cgccctgccg acgaccgagt cgagttcgcg caccagcctg ctcaccgcca
    68821 tcgtccgcag ccggagcact tcgtcgtcgt ccagcccttc cgccgcgatc cgttcgatct
    68881 cctcgtcgac gacccgcacc gccttgtccg ccgcaccgcc gggggacagg aaacccgaca
    68941 ccacgaacgc gccgggatcg cggaccgcga gcgagtcccc catcaggccg agcccggcgg
    69001 acacgtccgc gagcgtgccg tcggcctgca ccagccgctg gaccagcctc gacgactcgc
    69061 cgcccgcgag cagatcggcg agcagctggt gggcgaggta cgaccggaat tcgccgatcg
    69121 ggtcggggac ccgccagccc gtcgcgaacg cggcgagcgg ggcgagcggg tcccggtgcg
    69181 cgccgcgccg cgacccggtg agcgccggtt cggcgaagct gggccggacg gggaccgggc
    69241 gggcgggcac ggtgccgaag tggcgggcga ccaacgcggt ggtctcttcg acgtcgatgc
    69301 cgcccgctac gcacagcacc gcgttggccg gcgcgtagta ctgctcgaag aacgcgttcg
    69361 cctcggcgac ggtggccgaa tcgagatcga cctgcgagcc gtagccgtcg tgggtgttgg
    69421 cgaagccgtc gaacagcagt ggcggcaggt gcagccacgg aaaaccgccg tacggccggt
    69481 tcttcacgct ggtgttgatc tcctcggaca ccacgtcgac ctggttgcgc aggtttcgct
    69541 cggtgatacg gggcccgcgc atccggtcgg cttccaggaa gagcccgcgt tccagcgcgg
    69601 tgctgggcag ggtctcgtgg tagacggtgt agtcgaggtg ggtggaaccg ttgaaagagc
    69661 cacccgcgcc ctggacgtag cgggcgtgcg ctagtttcgg caccttctcc gagccctgga
    69721 acatcaagtg ctcgaagagg tgcgcgaaac cggtgcgccc caccggttcg gaccggatgc
    69781 cgacgtcgta gagcaccgcg atccccacca ccggaaccgc cgtgctcggc gcgagcacca
    69841 cccgcagccc gttcggcagg gtgaaccgct ccaggcgatc accgatcagc ggttccggca
    69901 ttggtcttcc gttctgacgc gtcgaagggg aacgcctatt tgtcgtcgac gtagatgtcg
    69961 acccagttgt cgcaccaccc tcccccgttc ggtgcgggct gacagaccgc caccgagcca
    70021 ctccagtagc cgcgcgcgac aacctcggtg aggttgaccg ggatgctgcc cggcccgcac
    70081 cgcgtcgcgg agttttgatg gctgatccac gcgccgggga agtgcatcac ctccatggtc
    70141 gcgaagtagc agccggagtc cgcgacggtc agcgtcccgt cggcgtgcac cttcccgtcg
    70201 tacgggtgcg gaccggccgt ctcgtagtgc gcggtaccgg tcgccgagcc gccgttgtac
    70261 cgcgtcgtcc agtttttcga cgcggcatcc gcggtgcctg ccgtgatcag taccagtagc
    70321 gcggtcgcca ccagagccgt cagtctgcgc atggtgtttc gccctcccca gggttttccg
    70381 tcgtggacga gatcacaatt ccccggcgga gcccgcgccg ccaaccgcga acgggctccc
    70441 aaccaggcct ggccaggtgg ctacttcagc tgggcgtggt ggcacgagga ccggccggtt
    70501 tcggcatttt ggtggatgct ccccgaattg ggcggcaaat agtgtccggt tcggtaaaac
    70561 gcccgaatca ttttgaggag ccgatcatga accgtatcga gtccgccgcg gccgagtcga
    70621 acctggaagt gctggaagtc agccgcgact ccgcgacgcc ggtgctgacc ccggtcctga
    70681 tcaccgtcac cgctttcgcc gtcggtaccg gtgtcggcgc cgtggactgc gcgcgtcacg
    70741 ggtgcatcga cgaaagcggc gaaggcgtgc ggctgaacga cgtccgcgag atgtcggtca
    70801 ctgagctgat gcaggcgcgc cgggacgcga cttccgtgta accgccgtcg aaacgcggca
    70861 tgccggggag agcggttggc tccccggcat tttcgtgccg ggagcagggc ggggcgggcc
    70921 ggtggacgcg ccacgggccg gtcggggcga aggctcgggc ctgcccaggt ggctaggtcg
    70981 ccggtagcca ccccgagcgt cctcaagggc cttgccgccg gaatggggtt cgggtgaggc
    71041 tactgctcga gttcggtttc ctcattttgg tggatgctcg ccgaatcggg aggcaaatag
    71101 tgtccggatc ggcaaatctg cccaatcatc tcgaggagct gaccatgaat agaatcgagt
    71161 ccgcagcggc cgaatcgaac ctcgaagtgc tcgaggtcag ccgcgactcc gcgaccccgg
    71221 tgctgacccc ggtcctgatc accgtcaccg ccttcgccac cggcgtcggc gtcggcgccg
    71281 tgcagtgcgc gcggcacggg tgcatcgacg agagcggcga cggggtgcgg ctgaacgaca
    71341 tccgcgagat gtcggtcagc gagctgctgc aggtgcggca ggacgcgact tccgcgtaac
    71401 ccgtagtcaa gacggcggat gccggggagc cgcacgcgct tcccggtgtt cgccgaccat
    71461 catccttggg agagcacaga tggctcaggt ggacactccg caggtcgaca aggtcatccg
    71521 ccagacggag gtgatcagcg cgacgggcat cgcgctcgcc tcgctcgaat acctgatgcg
    71581 ccccaagcac ttcgaagagt ccgggctgct gagctggcag gtcggccgca cgaagtaccg
    71641 ctggacgtcg aggaagtccg ccgacgtgct caacccgctg ttccggccgc cgggcgtgca
    71701 gggcgtgatc ggtctgcgcc tgaccgccgc gtcgctgctg atcgcccccg gcgccaagca
    71761 gagcgtgcgc accgcggcgg tggcctacct cgccgtttcc aactggctgc tgcacatccg
    71821 caacagttac ggcaccgacg gcaccgacca catgaacatg ctcgtctacg ccgcgctgac
    71881 cctgaccaag ctcttccccg gtgacaccaa ggccaaggag atctgcacca agttcatcgc
    71941 gggccagtcg gtgctgtcct acctcgccgc cggagccgcg aaggccgttt caccgtactg
    72001 gcgcgacggc agcgcgatga gcggtgtctt ccgcacccac acctacggcg aacgccacgt
    72061 cggtgagctg ttgaagaagt tcccttcgct ggcgaaggcg ggcggctggg gcacgatcat
    72121 cggcgagtcg atcttcccgc tggtcctgtt cggcggcaag aagaccgcgg tgtcgctgct
    72181 ggcgaccggc gccgcgttcc acgcgggcaa cgccgcgttc atgggcctca accggttcct
    72241 gtgggcgttc tgctcgacct acccggcggt catgcaccac tcccgaagcc tccgcaagcg
    72301 ctgacgcacc gaaagaggct cgtcatggcc gctccagtcg ccggtgtcta ccgccggttg
    72361 ttcagtctca tcaggcccta ccgcgccggc ctgtccgtcg ccgtggtgct cggcctgatc
    72421 agcagcgggc tcgcgctcgc ccagccgatg gtcatcggcg cgctggtcgg caagatcgtc
    72481 gcgggcgccc cggccaccgt gcccgcgctg gcgctgggcg ggctgttcct gaccgatctg
    72541 gtgatcggcg gggtcgaggt ctacctgctc ggccgcgcgg gcgcgtcgct cgtgctggac
    72601 tcccgccgcc gcgtcgtgcg caggctgctg cgggccccgc tcgggctgca cctgcggcgg
    72661 cagcggggcg atctgttcac cgccgcggtc gccgacacgg acctgctcaa gacctccctc
    72721 atgcagggct tgctcaacct cgtggtgagc gcgttgatgg tggtcggctc ggtggtcctg
    72781 atgaccgtca tcgacccggt gctcacactg tccactttgg ccgttctgct gctgtcgggg
    72841 atggcgacgc tgatcgtcgc caaacgcgtc cgcgcggcgg gtgtcgagac gcgggaacgg
    72901 gtcggcgact tcgcctcttc cttgcagcgc gcgatcggcg cgatccgcac ggtgaagctc
    72961 agcagggcag aggaacggga ggaagccagg atcggcgagt tcgccggggc cgccttccac
    73021 accgggatgc gcggcgtccg gctcgagtcg gcgatggcgc cgatcatgaa cctcggcatc
    73081 cagggctcct tcgccgctgt gttcaccgtc ggcgcgttcc gcctcgcggg cggctcggtg
    73141 gacaccgcgc acttctcctc gtacctgctg tacctgctct acctgatcgc gccgctgatc
    73201 agcctgttca ccgcgttcgc gcagatccag ctcggcttcg ccgcgatgct gcgggtcgac
    73261 gcggtcgccg acgttccgga agagaccggc ggcacaagcg aaccgaagcc gatgaccgga
    73321 accgcactgt cctttgagga cgtcacgttc ggctaccagc cgggggtgcc caccgtgcgg
    73381 gggctcacgt tcgacatccc gcgccgcggt ttcgtcgccg tcgtcggccc gtcgggtgcg
    73441 gggaagtcga cgatcttcac cctcgtcgaa cggttgtggg acgtggactc cggccggatc
    73501 ctgctggccg gccaggacat ccgcgacctg tcgttgcgcg atctgcgcgg cagggtcggc
    73561 tacgtggagc aggacgcgcc ggtggtggac ggcaccatcc gcgagaacct ggtcttcgcc
    73621 aaaccggacg cgaccgagga gcagctcgcc gacgccgtcg ccaaggccaa cctgcgccgg
    73681 tggatcgatg gcctcgaaca cggcctggac accgaggtcg gcgagtccgg cacggcgatc
    73741 tccggcgggg agcgccagcg catcgcgatc gccaggatgt tgttgctgcg ccccgaaatc
    73801 ctgctgctgg acgaggcgac ctcgcagctc gacaccgagg cggagatcgc gctcggcacc
    73861 tcgatcgccg cggtgtccgc ggactgcgcg gtgctggcca tcgcgcaccg gatggccacc
    73921 gtcgtcgcag cggaccggat cctggtcgtc gacgagggca ggctgcaggc agtgggcgac
    73981 cacgagtcgc tggtcgccac gaacgagctc taccagcgcc tggtgcgcac ccagctcggc
    74041 gggaccgagc aggggaactg ggccgtcgaa accgaactcg ccgggaggat ccgatgaagc
    74101 cgacgaccgt gaaactctgt gcgggcgcgg ggatcgcggc cgcgctcgcc ccgctcgccg
    74161 cgggtttcac cctccagcgg cgggcgacgc ggcgcgacga cgagaagtac ccgggtatcg
    74221 gcgaacgggt cgacgtcggc ggctaccggc tgcacgtcca caccgccggg ctggacaacg
    74281 aaggcccaac cgtgctgttc gaggccggga tgtcgtgttc gctggaggtg tgggcgtggg
    74341 tgcaggatga gatcgcgcgg gacactccga cggtctccta cgaccgggcg gggctcggca
    74401 ggagtgaccg cggccctcgg ccgcgcacgg ccgaggacat gcgcgcggaa ctggaccagg
    74461 tgctcgaggc ggcgggtacc aaggggccgt acgtcctggt cgcgcattcc ttcggcggcc
    74521 tgctggtgcg caagttcgcc cacgaccatc ccgaccgggt cgcgggcatg gttctcgtcg
    74581 actcctcgca ccccgagcag atggtccggt cggcgcggca ggcgctcggc ctgccgctga
    74641 tgcgctcgac gatccagaac gcggttttgc tcgcggccgt cggcatcaac cggctgtccg
    74701 accgctacat cgtgtccggg gtggagcacc tgcccgagcg cgtgcgggag gcggcatgcg
    74761 cgcggatgct ggcccaccgg acctggaaga ccacgctgca ggagctgcgc ggctggctcg
    74821 acaccgtcaa cgacgaggtg cgcgacacca cgcttccggc ggacctgccg ctcgcggtgg
    74881 tcaccgcgga cgtgccgaac cgcgccgacc cggtgcacga cgagctgcag gacgagctgg
    74941 ccgcgttgtc cgccaacagc aagcggctgg tcgtccccga ttcggaccac ctcgggctgg
    75001 tgatgaagga gcggttcgcc aagtacgtca ccgaggccgt cgcggacgtc gtgcgggcgg
    75061 cgcgcaccgg ccgccccctc gactgaacgg acgcaggcag cagactggac ggagtggatg
    75121 atgagcgatt cccgccgggc acgggtggcc cggatcgtga tgggcggctt cctcggctcg
    75181 tggttcgccg cgaccctgct gagccaggac ccgttccgca agttccccgg cgcccggcgc
    75241 tacgacccga ccggcgcggc gatcccggac tggcggttct tcgcgccgag accgggtatg
    75301 cacgactacc acctgctcgt ccgcgatgag ctgcccgacg gttcggtgac cgactggcgc
    75361 gaggtgctgc cggtcgagca gcgcgcgccg cggcacttct tctggtacgc caaccgccgc
    75421 gcggagaagg tggtcgccga ctcggtcgtc ggcatcgtgg ggttcaccaa ggaggagggg
    75481 cggaagaagg aggacatcca gctttcggtc tcctatctca cgatcctcaa ctacatgacc
    75541 taccaggagg aacaccacaa cgacgcgaag cggacccagt tcctgatcgc ggcttcggcc
    75601 ggctacgacg aatccgagga gccgctgatg ctgttcctgt ccaacctgca cccgcttccg
    75661 tgagcgggta gcgcgcgatg accagactgg tcctggcagg ctcgttcacc gtcgatccgg
    75721 ccaacctcgc gaaactgctg tccgtggcac cggacatcga aacggtcgag gtggtcggtt
    75781 cggtcgaccg gctgtgcgaa ctcgcggaag ccggtaaccc ggtctccgcg ctggtgtacg
    75841 ccgatctgtc cgaaccggac atcgcgtcgg ccgcccagac cctggccagg ctcgacgacc
    75901 ggcacagcct catcgtggtc gtcgagtccg cgaccgtcgc gaaggtccgc tccacccttc
    75961 gcgccggggc gcgcggcatc gtgctgccgg acagcccggt cgaggaactg ctcaccgcgg
    76021 tgcgcgcggt gtcggcgggg cacctgttcg tgccggcgcc gttcctggct tcgctggggg
    76081 agcgcctttt cacgctcgcc cggcgcgccg cggacgccgg tgcccgcctt accccgcgcg
    76141 aggccgaagt gctgcgggtg atggcgttcg ggcacccgaa ctcggagatc gccgagcagt
    76201 tgttcatctc ggaggcgacg gcacgcagcc acgtgctgaa catcctgcgc aagctctgcg
    76261 cccgcaaccg gaccgaggcc gtcgcgatgg cctaccggga cggtttgctt gccgcggaag
    76321 acctcctgcc caccgcgacg gaatgagacg ccgtgcccga tcgacgcccc gaagaactgc
    76381 cgctgctggt gttcgacggc gactgcggtt tctgcacccg cgcggtgcgg tggctgttcg
    76441 ccaaggcgaa accggccgcg gaggccatcc ggtaccagca gctcgacctg gccgcctacg
    76501 acacgaccgc ggagcgcgcc ggccacgagg tgctgtggat cccgctggac ggcccgatca
    76561 gcggtggcgc ggacgggctg gcccggttgc tgcggaccgc gaagacgcgg cgctggcggg
    76621 ttgcgggccg ggtgctcggt gccgtcccgg tgcgctggtc cgcccgcccg gtctaccgcg
    76681 ccgtcgcgcg caaccgccat cgcctgcccg gcgggaccga ggcctgcgcc atccggatcg
    76741 tgtcctcgtg agggagcgcc cccgaacagc cggccggtgt ccgtgacccc cgttttcggg
    76801 caccggccgg tttccacctc agctcgcatc ggatttctcc tccgccgtgc cgtttccgat
    76861 gatctggttc agcgtgctga cgtattcgcg gtacgcggcg ctcccggttt cggtgaggct
    76921 gaaccaggtg gtcggccggt tccgcgccac gcccttggtg acgttgacgt aatcggcgtt
    76981 ctgcaggacc gcgatgtgct tggacagcaa cgaatcgctg acctccacgg tttccttcaa
    77041 gtacctgaag tccacttcgt ccgtcacggc cagtaccgcc atcaccgaga gccgcacggg
    77101 ggagtggatg atgtcgtcca gtttgcggcg cgggtggccc ccggtcatcg cttgccgagc
    77161 acgacggcgc cggcgaagca gatcgcggcg ggcaccaccc cgggcagcgc ggccgcgagt
    77221 gtgccctgct tcagcacgaa gatgtcgagc gcgatcaccg cggcgcagct gaggatgtac
    77281 ccggtcagga gcagctgttc gatccgcagc acccggtggc ccgaggtgct cgccttctgg
    77341 atgcccgcga cgacgaaggc ggccacgatc gggaacagga aaagcaggga gtcgtacggt
    77401 ttgacgctcg ccctcggcac gccgccgacc accgcgaaga agccgagcgt gaggaccccg
    77461 agcaacgcca cactggtcac gtagagcttc ttggtccgcc cgaccttgct ttccagctgc
    77521 gagatcctgc tcgtggccgc gatgtggtcg agcgggccgt cctcattgac agccatcgga
    77581 ttcctttctc ctggaagggg aacctgaacc accatcccac acacttgaag actcttcaag
    77641 tgtcctggtg gtggccaccc gggcataccc gtccgggcac atccgcccgc cgcctcgcga
    77701 atccgcgcat tggtggatgt tcggccgctg gggccattct aaattcgttg cgtaattcca
    77761 ctacgaggga agaggtagca gtcatgaatc gcatagaatt cgccgtcgcg aagcatgttc
    77821 cggacaccgc gtcggcccac ccgctgctcg aggtcaccgc cgagcagatg atcacctgta
    77881 cgccgacgat cttctcggcg ttcggcatcg gctacctcgt cggcaaggcg ttcggcccct
    77941 ccgaggagtc cgagcccggt gcggccgcgg cgttccacga caacatcgcc acgatgaccg
    78001 gtggcgagtt gatccagttc cgccgcgact cgctcgcctg agccacctga atgaggaagg
    78061 tcgtccccgt gaccccaggg aacggccttt cttttgtgat gtcgagcttg gcgaattctt
    78121 gaatcagtgg atgtgtggtc gtcgggatcg cttcagattt gtcgggtaat tcaattccgg
    78181 gggaggagtc gtgaatcgtg tggagttcgc cgccgcgaag cagatttccg accccgcgta
    78241 ggcaaggctt gctcgtcgga ggagtccgag gccggtgcga ccgcggcaac atcgccacga
    78301 tggccggtgg cgagttgatc cagttccgcc gcgactcgct cgcctgagct gcccgttcga
    78361 ggaaggtcgc cccccgcgag cgctcgtggc cgggggctgc gcggcgtttt ccgagcctgg
    78421 ccactcgggc atagccgtcc gggcacatcc gcccgcagcc tcgcgaatcc gcacattggt
    78481 ggatgtttgg ccgcgtgagc cactctaaat tcgttgtgta attacagttt gagggagagg
    78541 taacacccat gaatcgcgta gaactcgccg ccacgaagca gattcccgaa gccacgtcgg
    78601 cccagccgat gctcgaggtc accccggagc agccgatcac ctgcacgccg accatcttcg
    78661 cggcgttcgg cgccggctac ctcgtcggca aggcgttcgg cccctccgag gagtccgagc
    78721 ccggtgcgac cgcggcgttc cacgacatcg ccaccatgac cggcggcgag ctgatccagt
    78781 tccgccgcga ctcgctcgcc tgagccacct gaatgaggaa ggtcgtcccc gtgaccccca
    78841 gggaacgacc ttccttttca cgtgtgccgg gagttgtacg aacgccggtt ccgcggctct
    78901 agctgggacc agtccccggc ccggtcgcct agcgttggct atgcccatcg cccttcgacg
    78961 gactttcccg gtcgtgaccg cgctggtcgt ggccgcctgc tcggccccgg ccgcaccgcc
    79021 agctccggca ccgccgtcct cgaccgcgcc gcctggtacc accaccgccg cggaatcgcc
    79081 gttctgcacg gacctgcgcg cattgcaggc gggtgtcctg gtctaccggg cggacgtgct
    79141 caaagccgct cgcagtgagc agcaactgga tgtcgacggg atgcgacgac gagccggagc
    79201 catcgccagc ctcggccaat cggtactggc acacgcgccg caagccatct ccgagcagat
    79261 ccaccacgtg ctcgacgcga tcgccacctc cgccgaccgg atggccaagc gcggcgcacg
    79321 ggtccgcgat gtctacgacc ctcttttcac cgacgcggcc cgccccgcat tcgacacggt
    79381 ggaccactac gactgcacgg ccaccggcgg gtgaccgcgc accgcccacc gttcgatagc
    79441 gattccggaa tcgctatcga acggtgggcg aggccgagga gccgttggtg gtcgcggtgg
    79501 gatgctccat gccgcggtca gccgatgggt tggtagtcgg taacggacgc ggtgaagacg
    79561 gcgacctttc ggtaggaccg agaggggagc agcgtggcgt tgttcggtag caaggagaac
    79621 aaggagctgg aagggctgca gcagcagctc gccgcggcga acgagactat caccgagttg
    79681 cggggatggg tgagccagct tcgaggtgcc ggggttcccg agatggaggc cgagctgcgg
    79741 aatctgcgct cggcggtcga cctcgcgaag gaggaacgtg ccgggctcgc cgcctcgcag
    79801 cagaagttgc gggccgaggc ggacatgtgg caccagcgcg tggtcgagac gcgggacgtg
    79861 gcgttgttgc aagaggtcgg actctacgaa tacgcccatc ctctggatga cgcattagcg
    79921 tacaaagacg cgctcaaaga actcaaggag cggacgaagg cggcggccaa gagcgatgcg
    79981 gtgacgtgcc aggtggactg ggcggtgaac ggctcggtca aggaggggca gaagctcggc
    80041 agggacatgg ccaagctgat gctgcgggcc tacaacgccg aggccgacaa cgcggtgcgg
    80101 gtggtgaagc cgcacactcg cgagtcggtc aagaaccggt tgacgaccac acgggacacc
    80161 atcggcaggc ttggcaagct gatgcggatc gtgatttctc cggactatca ccggcttcgg
    80221 ctgcgcgaaa tcgacctgac cgcggactat ctgatgaagg tcgaagtgga gcgcgaggcg
    80281 gcgcgtgccg agcgtgaccg gcttcgtgag gaagccaagg tgatcaagga actcgagcgg
    80341 aagcgcgcca aactggaaaa ggagcgtgcg cactacgttt cgttgctggg caagctggag
    80401 tccacaggcg acggcgaagc gctggccaag gctcaagagc agttggcttc gatcgaccag
    80461 gcgatcgccg gggtggagga gcgtgccgcg aacgtgcggg tcggctatgt gtacgtcatt
    80521 tccaatatcg gcgcgttcgg accgaagatg gtcaagatcg gcatgacccg taggcaggaa
    80581 ccgatggacc gggtgcggga gctcggtgac gcctcggtgc cgttccggtt cgacgtgcac
    80641 gccctgatct tctcgaagga cgcggtcgcg ttggaaaccg ctttgcacca acggctcggt
    80701 cacaaacggg tcaatcgcgt caaccaacgc cgcgagttct tctacgccac gcccgcggag
    80761 gtcaaggagc tcctcgtcga actgggcgac gaccacgtgg tcgaatacag tgacagatcc
    80821 gaagcattgg aatggcgcgc ttcccagccc agggggtccg ggtcggctcc gctcgaactg
    80881 gccgcggtcg gggcacagga agatgctgat ggtgacctct cggatgacgg gagggaatga
    80941 ccggtgaccc agccaccttt gtcggctcag ccgacgcgtc cggcggcgtg gttgccggat
    81001 ccgctggacg actcgttgat tcggtactgg gacgggactc gctggacgtt ccgcacggca
    81061 gaccggcccg catcggcacc ggttgcggcc gagcccgggg cgccggagcc ggtggaaccg
    81121 gcgctgcggc ccgacatcgc gcaggctgtc gaccgggtgc gcggactgct cgtcgggtcg
    81181 atgaaagagg tcaacctgtt ggccggtcac cttcggccag aggagcatgt cctggcgctg
    81241 accggagcac agggagaagg ccagggcgtg ctcgcctgca ccaaccagcg gctcctgttc
    81301 ctcttcgtcg gcatcattcg ccgccagttc ctgcaagtcg agtggaacca agcgagggca
    81361 gtgatctaca acggtggcac caagcagttc gccgtgtaca cgacccggcc cacgaaacgc
    81421 gcggtaccgg ctatggccgt gcgggtgaac aacgtcaagg acgcgcaggt ggtggccaac
    81481 gccgcggtgg aggcttcagc cgcaccccgg ctggacataa tctgagaccg gcgcagtgtc
    81541 cgaacccggt gccgacgatc cggcaccggg ctcggacgct ctactttcgc ctgcggactc
    81601 gggtgatgaa ccaggtcgaa ccgatgatca gcagtgcgaa cagcagcagc ccggcgccga
    81661 gtgtcgcgat caggacgacg cggtcgccct tcggcagggt gccgttgagc gtcacctgca
    81721 acgagccgac cgcgaaggcg atcgcggcgg tgaacacggc gaccacttcg accattcgca
    81781 ccggtgcgga ttgcacggtt tcccggagtg ccgtgttgtc ggctttcaga tcggcgatca
    81841 aggctttctg ctctgccatc caccgagttc gctgcgcctc cagtcgcacc gaattgcgct
    81901 cggtcaggta ctgctcctgg agctgctggt gacttccccg gtttcctgtc gcggggagaa
    81961 gttccagtgc ggtatcgata ctgcgcaagg cttcgtcgta gttctcgcac attctctgtc
    82021 cggcggccag gcgataatag aagatgttgt ctttcgggta tttgtcaata gcttcacgtg
    82081 cgtaggtgtg taccaattca ccctggcggt cgaacgggcg ggaccaccac agtccgttca
    82141 ggcagatgtc gatgaccgct ctggtgcgat ccggagattg ccaggcctcc tcgagcagtt
    82201 gcaccgcgtg ctcggaggtg atcgagtgcc tgccgaacgc ggcgaaggat tccagggcca
    82261 ggaacagcgg atcggtgcgg agcttgcccg ccgccaccag tggcgacgat gtgaggaact
    82321 cgcccagttc gtcgcagttg aaattggccc gaaacttccc ggcgtgataa agggcggcga
    82381 agtgcgcgat ttccggtgta cgggccttga cgacttcgtg tgtcgcactc tcgacttcgg
    82441 tctcggattc gacggtgtcc cgggtgatga aggcgtagcc cagcgcccac ttttcggtta
    82501 tcgtcgggcg gaatttcgtt gcaacattcc tttcgatcca ttcggcgcat agtcccgcgg
    82561 tggagatggt cgggtgatcg agaaagcgaa gtcgccagta acgatcggcg cagatgagtg
    82621 ccccgtcccc gacgaagtcc gcggagctga tcgcgaaatc aggttcggtg ccgttgtcca
    82681 agagccgttg tgcgtggcgc tcgcagagac ggtcgagttc acggcttccg gccgcagcac
    82741 gaacgagttc ggcgaagatg gcttcttcca tgctggcata tccccgaaca cctcgccgat
    82801 gttagtcggc cgtttctagg attgttcaga gtgaagacgc cgatcgtagc tttgttggct
    82861 ggctgatcac cacgccggcc gggcggtgcc cggtcagccg acggtggagt caggctcgac
    82921 ccgtcctcgc gcgggcgaag tgcggttccg ccgcttccag tcgtggtacc gagatgccca
    82981 gccgccgtgc ttcggcgagg gtgtcccggc agacctcgcg cggctcctcg gcatcggggt
    83041 gggagtgcgc ctcgatactc acgcgcaggg ccgtgacatg agcggtcagc caggcgagta
    83101 cgggggccat cagccaggtg ggcacccgga acagcagcac accgcctcgg tgacgtcgca
    83161 ggtcgatgcc gcgagccttg aggaccggca gcagttcgcg gccggtcaac agcgcctggc
    83221 gcagctcgcc cgtcgccccg gccagctcgg acagggaacc cagccgcagg ccctgtgaga
    83281 acaggcccgc atccgacacg aaatggaccc acagccagcc gcggaggtca ggttgctcct
    83341 tgatccggag gcctgcctcg cgaaacgcct ggcgcacggc ccgctcccgg tcggtcgggg
    83401 gctggccgag ggtgccgaag atgactgacg gcagcagcat cccgcggagc acgccgttcg
    83461 caccgaaacc gccgccggct tgcggaaaac cccaggcgat ccggtcgggc gggagtgcgc
    83521 cgatcgcggc gagcggctcg gtccagaggt tgccgaagac caggaccgtg gcccggccga
    83581 cgcgcgggga caggaaggcc gtcgcctcgt cgaggcggtg gtgcggcacg ctgagcacga
    83641 tcaggtcgaa gtcgtggtcc ggctccagcg cttcgcggta gcgcaccggc cacttctcga
    83701 cgacgcgccg cccccacggc cggcgtcgcg tatcgagcag gtcgaggtcc accgcgtccc
    83761 cgtaggtcgc ggcgcggccc ggccggacgt agaactcgac gtcatgtccg gcccgttgca
    83821 gggcccagcc gtagatggtg gcgatcacgc ctcggccgaa catcaggatc ttcacgctgc
    83881 acctcgtggg gtacgatcga tttggagatc atctccactt tccaaaatat ggagatcacc
    83941 tccagttgtc aacgcgaggg agcgcatgac caccgacaag ccgctgcggg ccgacgccca
    84001 gcgcaagcgc gaggccctgc tcgccaaggc gcgggaggtc ttcgacgccg gcgacttctt
    84061 cgacctccgc ttcgatgact tcgccagcct ggccggggtg ggcaccggca cgctgtaccg
    84121 gcacttcccc acccgggagg cgctggccgc ggcggtctac cacggtgagg tcgccgcgct
    84181 gtgcgatcgc gcccgccacc tggaggccac actgcccgcg gcggaggctt tggcgacctt
    84241 cctccgtgac atggtcgacc acatcgccgc ccaccagggc ctggcccgga cactggccac
    84301 gctcatggcc gatcgttcag gtgctctcac cgaaggcagt caggcactgg aacaggccgt
    84361 cgccgacctg gtgaccgccg ccgcgcggga cggcgccgtt cgcgacgacg tggatgccgg
    84421 tgccgtgatg atggcgctgc acggcatcgg tgcggctcac gaccgccccg gttggcggac
    84481 cgaggccgac gatctcgtca ccctcgtgct ggacggactg cgccgaccgc actcgaattg
    84541 atggctcgct cgattcgccg gtctgtttac gaggcacgaa tcggcagatc agaacccggt
    84601 gaccgagatt tcctgggcgg cggccgaact caggctggga cgcgctcacc gtggatatgg
    84661 gagaaccgga gctgaaactt cgggtaggca cctgtcgaat gcgcatacga ctagtggtga
    84721 agtagcaaat tctggcgtcg atttcgacct gggatcgcgg gttgtcgctg agcggacttt
    84781 cgttgcgaca gggaattcgg tccattgggt gcgaagtcag ttgtcacttc ccattgcctg
    84841 gtcgctccgc gggtccggcg cgaccagcgg ctcggggcgg cacccggccg ccgccttccg
    84901 agcgatgtta aagccaccaa tagttgcact aagatcttgt tcggagtagg aaggtcataa
    84961 ggggttcgcc acttcggcgg cggcgtgtcc gacttccatc ggcaccacca cgaccacctc
    85021 gttctgtggc cggacgccgg gcgggccgga gcacaggagc ccgaccggcg cgaccaggaa
    85081 cgaaaggact gaccatgatt cagcacattt tccacggtga cgtcaggatc gcctacgaag
    85141 aatccggctc cggtgaaccg ctcgtcctgc tgcacggcgg ggagagcggc cgcgtccagt
    85201 acgacacgtt ccggccggta ctcggcgacg ggatccgggc catcgcctac gaccagcgcg
    85261 ataccggcga ctccacgaat cccgcggagc cttaccgggt ggacgatctc gccgacgact
    85321 gcgcggcgct gatccgaggg ctcggctacg aacgtgcgca tatcttcggt gcctcctacg
    85381 gcggcgccat cgccttgcag gtcgcggtca accggccgga ggtcgtgcgg acgctgaccg
    85441 ccggaaccgc gatcccgcgg ttctccgccg cgccggcctc cgcgcagaac ctcactcacg
    85501 cgacggaaga tcgcgcggcc aagatgctcg acgccgtcct gtccggaaaa gggcagcagg
    85561 aacccaaact gctcaccgag gcccggcgga ttctcctcca ccgccccgcc ggggcggaca
    85621 agcgccggat ggacgcgatc cgggagttcg acgttctggg acggctgggc gagatcaccg
    85681 cgcccaccct gctgatctac ggcggcgacg atccgctcgg cagggtcgag tacggacagc
    85741 ggattgccga ggcggtcccc ggtgcccgcc tcgaggtact ccccggcatg cggcacggga
    85801 tcacgctgga ggccaagcac gaggtggccg cgctgcttcg cgacttcatc ctgacctcgt
    85861 cgcggtagac cacccgccgg accgggccgg gtgaagtccc gccgcggccc tattcggcgt
    85921 gcaccgcgtg aatacccgcc aggatgatgt cgacgacgtg ctccgcgtcc gcg
//
