LOCUS       NZ_CP059997            12716 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2472071
            Orig. end                         :: 2484787
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12716
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="14"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12716
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12716
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7716](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7716
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            47..388
                     /locus_tag="HUW46_RS11235"
                     /old_locus_tag="HUW46_02212"
     CDS             47..388
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010694135.1"
                     /locus_tag="HUW46_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02212"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_215547219.1"
                     /transl_table=11
                     /translation="MRADAVRGHLDGLLLAVLETGPLHGYAIISTIQERSGGALELPTG
                     TIYPALNRLERLGLLDSSWQSVGERRRRCYQLTDAGRRSLDTQRGAWREFTATISAVLN
                     PAPAPRTAR"
     gene            385..1041
                     /locus_tag="HUW46_RS11240"
                     /old_locus_tag="HUW46_02213"
     CDS             385..1041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010307709.1"
                     /locus_tag="HUW46_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02213"
                     /product="hypothetical protein"
                     /protein_id="WP_215547220.1"
                     /transl_table=11
                     /translation="MTTVERRTDPVDDYLAALAAAVHGPAKVKARMLEEIRGGLEDAVS
                     AQGGDSHAAALALRDFGTVEEVASSCQTELTIAQTRHTSRALALTVPFLLACWYLIRTA
                     SPSGDGQVARVAQLVAAHLTGAATIAAVLAAAALAATGTLARWLPTPPKLPRVVAWTST
                     STGAAMAVATVALLSASPASANWPLVVLAGLFTAASHAMVAGSARACRECARLTC"
     misc_feature    complement(1109..1123)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.83"
                     /tool="antismash"
     gene            1131..1580
                     /locus_tag="HUW46_RS11245"
                     /old_locus_tag="HUW46_02214"
     CDS             1131..1580
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495573.1"
                     /locus_tag="HUW46_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02214"
                     /product="hypothetical protein"
                     /protein_id="WP_215547221.1"
                     /transl_table=11
                     /translation="MFKVLLSVHIFAVILVVGPIAVAASLFPRYAKQLAAEEGEVATRS
                     TGVATLLHRICRGYAVVGIAVPVFGIGAGAHLGVLGDYWLIASMILTAAAAALLVLAIL
                     PAQRRAMTSGSVSKLAMTTGIFNLLWAIVVVLMIVRPGSTTGMHG"
     gene            complement(1655..2083)
                     /locus_tag="HUW46_RS11250"
     CDS             complement(1655..2083)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_215547222.1"
                     /transl_table=11
                     /translation="MPSNDQNTPTITVRQAEDRARNYAAELRSALPAEAMLEDRGVQQN
                     ACPDPSGVGFEKRKHVNADYWVRGLDPADHDKYFDAMKSWLTKNGWNIDKDSRPADMFM
                     NAVRSDDGFSMSFQANKKGGLALGTSSPCVWPNGTPEP"
     gene            complement(2172..3848)
                     /locus_tag="HUW46_RS11255"
                     /old_locus_tag="HUW46_02215"
     CDS             complement(2172..3848)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018018.4"
                     /locus_tag="HUW46_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02215"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_215547223.1"
                     /transl_table=11
                     /translation="MVSLADVKNWKPEVLNEIATTLRQRQQTLVHSGDDFGRLMPMASW
                     TGPAADAAQGTHNRLMTRLMALTAVTSAVSKGLMQASDAIPPVKHAIEAAEELARKYGF
                     TVDANGQVTDDFAGKEPPPEMHPEDRAHVHEQVGADLTQALRTAEDIDNDLDSLFFRAA
                     FGEYADFHQGTVAAAADAGLKEIGLTLPEPPPGATPAQNAAWWATLSKVGQTIYARDNP
                     GIVGKLDGVPVAVRDEANQRVLVRQKESLQKQCDDVQKKIDGLRRTAGGEIVLNDQSEY
                     EDLKSQIDDINGKLGGIKSIEDRLQNAVNGQKAYLLGVNTENAGQAIVSSGNPDEAENV
                     ATFVPGTGAKLAEVGDQVARSDLMLRSAQDAGSPSTAVVTWIGYDAPQNIILDSPRSVF
                     ADNAERPLHDFQAGLLASHPNDPSHTPPHTTVIGHSYGTTAIGQTARDHGLAADDLVFA
                     GSPGVGVRHADQLHLDNVPPDQVGKHVFSTAAPTDPIPILTNFHTENTDDIDPLGPDPT
                     MPWFGGQSFDADASSPFHSHSDYWEPRSSSLRRMGQVIAGN"
     gene            complement(3848..4156)
                     /locus_tag="HUW46_RS11260"
                     /old_locus_tag="HUW46_02216"
     CDS             complement(3848..4156)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_02216"
                     /product="hypothetical protein"
                     /protein_id="WP_215547224.1"
                     /transl_table=11
                     /translation="MGFTSVPETLRATSRSAQSALGELRGADCGKPVAGVAGALPGAKA
                     GANATMYSDTWSMTFIEWCTGAEAHGTAFATAADTYVAGDHAAAGAIPGSDAPGGPF"
     misc_feature    4181..4195
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.08"
                     /tool="antismash"
     gene            4334..4939
                     /locus_tag="HUW46_RS11265"
                     /old_locus_tag="HUW46_02217"
     CDS             4334..4939
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945565.1"
                     /locus_tag="HUW46_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02217"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_215547225.1"
                     /transl_table=11
                     /translation="MVREQAGRILAANLRVLREQAGMSLSELARRSAIAKGTLSQLESG
                     TGNPTIDTVFSLSNALGVPVSSLLTERADPDVVLVRGGGLEVLSSNAVDLRMLRRMDVT
                     ETVFELYDQRVRPGEVQHSDGHPGREHVVVTSGVLRVGPPDSPFELQPGDYVCFPAQNP
                     HIYETIGGPVLSVLLLEYPADAGPPTLGGSCTAGERRG"
     gene            5001..6161
                     /locus_tag="HUW46_RS11270"
                     /old_locus_tag="HUW46_02218"
     CDS             5001..6161
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010697121.1"
                     /locus_tag="HUW46_RS11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02218"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_254126064.1"
                     /sec_met_domain="DAO (E-value: 2.1e-63, bitscore: 214.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHPDVVVAGAGVIGAACAEALSAAGLVVTVLDRGAPAGGTTAAG
                     EGNVLVSDKEPGPELDLAKASRRLWPELLEGLRAELGTELADAEWDPKGGLVVSTGEAG
                     PLRDFAAVQRESGVDAQVIGAEEAAELEPLLTKEITAAVWYPEDAQLQPVLAATTLLAA
                     VRARGGTVLSGHTALGVTTSGGSISGVRTNHGVLPCGAVVNACGPWSGEFAAAAGAPIA
                     VLPRRGMVLVTAPLPESVRHKVYDADYVGAVASGDADLQTSTVVESTAAGTVLIGSSRQ
                     RVGFDETIRVDVLAELARKAVTLFPFLAAVPVMRAYGGFRPYAPDHLPVIGEDPRLPGL
                     WHATGHEGAGIGLAAATGRLLADLFRGNESIVDHNPFRVDRAEVLA"
     gene            6158..6415
                     /locus_tag="HUW46_RS11275"
                     /old_locus_tag="HUW46_02219"
     CDS             6158..6415
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945563.1"
                     /locus_tag="HUW46_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02219"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_215547226.1"
                     /sec_met_domain="Fer2_4 (E-value: 9.3e-24, bitscore: 82.4,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVSVDGEPMTAAPGQTVAGLLLAAGRSSWRSTRGGGRPRGVFCG
                     IGVCFDCLVVVNGVPDVRACQRTLADGDRISTQHGAELPS"
     gene            6412..7716
                     /locus_tag="HUW46_RS11280"
                     /old_locus_tag="HUW46_02220"
     CDS             6412..7716
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945562.1"
                     /locus_tag="HUW46_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02220"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_215547227.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2e-27, bitscore:
                     95.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 8.9e-08, bitscore:
                     31.5, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTVVGAGPAGMAAARTAAEAGADVLLIDSGTKLGGQYHRQNSL
                     YTGEKFALPANVTHLPDTAVWAVEPGPRLHLRTGPADGPGRTGRTIDADALVLATGAYD
                     RALPFPGWDLPGVYTAGAAQAMAKGQRVAVGRRVLLSGTGPFLFPVAESLLGVGAEVLG
                     VLEANHPVTGWLANPGGLLAGAAKAAELGRYLAVLARHRVPYRPRTTVLAAHGEHRVEA
                     VTTARVDRDWRVVPGTEQRVECDAACVGFGFLPQLELAVAAGCALRDGFVDVDFTQRTS
                     VPGVFAAGELTGIGGAVLSEDEGTVAGAAAAGAPVPRRALRGVRAGRRFAAALEAAYPI
                     RSGWRDRLTGDTLVCRCEEVTYRALCDAVEKRDATGVRALKLVSRAGLGQCQGRICGRT
                     VAELTGTETTAFSKRPIAAPVRLGELAEIPKEDKK"
     gene            7713..8636
                     /locus_tag="HUW46_RS11285"
                     /old_locus_tag="HUW46_02221"
     CDS             7713..8636
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945560.1"
                     /locus_tag="HUW46_RS11285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02221"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_215547228.1"
                     /transl_table=11
                     /translation="MTQEKLDGVIVATALPYAEDASAPAGLRVDLDRYAEHCRWLIDNG
                     CRGIGPNGSLGEYSSLTSDERRAVARTAIEAVGDDGIVVVGVHGVGAHQAREWAEKAAE
                     DGAHGVLCLPPTMYRANTAEVMHHYEQVAGVGLPVMVYNNPIDTKVDLLPPVVAELAQL
                     PNVVAVKEFSGDVRRVLEIRELAPELTVVAGADDVALEALLMGATGWFAGFPNVFPAES
                     AHLFSLAQQGKLAEARALYEPLVAAFRWDSRTEFVQAIKRGMELVGRFGGPCRPPRGPL
                     SEDKLAALDADMRRAIAHLAAHPVAA"
     gene            8638..9639
                     /locus_tag="HUW46_RS11290"
                     /old_locus_tag="HUW46_02222"
     CDS             8638..9639
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646747.1"
                     /locus_tag="HUW46_RS11290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02222"
                     /product="proline racemase family protein"
                     /protein_id="WP_215547229.1"
                     /transl_table=11
                     /translation="MRASRYFSAVDSHTEGMPTRVITGGVGVVPGATMAEKRVHFVEHL
                     DHLRELLVNEPRGHAAMSGAILQPPTRGDADWGVIYIEVSGCLPMCGHGTIGVATVLVE
                     TGMVEVTEPVTKVRLDTPAGLVVAEVAVTGGRAKAVTIQNVPSFSLRLDAEVDVEGLGT
                     VRYDLAYGGNFYAMVALDDLGIGFDKSQKDRMLTAGLSIMDAINAAEKPVHPADPAITG
                     CKHVQFVAPGKDGSDARNAMAIHPGWFDRSPCGTGTSARMAQLHARGELAIGADFVNES
                     LLGTRFTGRLIEETRVGGLPAVVPTVTGRAWITGMGQYLLDPTDPFPRGFTL"
     gene            9636..10979
                     /locus_tag="HUW46_RS11295"
                     /old_locus_tag="HUW46_02223"
     CDS             9636..10979
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020668267.1"
                     /locus_tag="HUW46_RS11295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02223"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_215547230.1"
                     /sec_met_domain="Aldedh (E-value: 2.1e-126, bitscore:
                     421.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRVVSTSPQRPADVVADCPATPAEQVTRTVAESLAAQREWARSA
                     AADRAAALTAMADAVAGHRRELADLVIREVGKPSTEALGEVSRTVAILRYYAQQCFEPV
                     GETYPRAGGLDFTVRRPHGVAGLITPWNFPLAIPVWKAAPALACGNAVVLKPAPAATGC
                     ALRLAELFAPHLPEGLFSVVPGLGDAGAALVGSADVVSFTGSGAVGRTVAVAAAERGVP
                     AQCEMGGLNASIVLPDADPDRAAAQIAAAAMGFAGQKCTATKRILVVGDAANFADALVA
                     KVEALGVGDPADEGVAVGPVIDEAARQRVLAAADGKVLTGGGSPGGDGWFASPTVVTGL
                     GQDAPLNTTEVFGPICTLTGVSTVDEALRMANSGTYGLVTALYSNDLDAALSFVDQCES
                     GMVKVNAPTSGVDFHLPFGGEKESGYGGREQGKAALRFYSSSRTVQLG"
     gene            11055..12476
                     /locus_tag="HUW46_RS11300"
                     /old_locus_tag="HUW46_02224"
     CDS             11055..12476
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693626.1"
                     /locus_tag="HUW46_RS11300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_02224"
                     /product="amino acid permease"
                     /protein_id="WP_215547231.1"
                     /transl_table=11
                     /translation="MATKPLTDRGLFRRKPIDDIEEPVNGDTGLKRVMGTWQLTALSLG
                     GLVGAGVFSLSGVVANQLAGPGVLISFVLAVLASAAAALCYAEFTSLIPKAGSAYTYAY
                     AVLGEVVGWLIGWDLLLEYTAIVAVVAIGVSGYLSYLVQQLGFDLPDWMLGAPGTGSGH
                     RIDLFAMLMCLLLAWILNRGAKSSARVETALVVMKVVLVLVVVVAGAFHIKGGNYTPFL
                     PYGIGGAVTGAATAFFAVYGYDAMSAAAEETDDARKKMPKAILLSLGIATVIYVLVCVV
                     LLGMQNYRDIDTQSPFSSALAAVGLPSLAIVVAVGAVLGITTSMFANMLAVTRVWFAMS
                     RDGLLPKWFAKTHPVRKVPSRVTWIVGVVSALIAGLLPIREAAELTNIGILAAFMVVSI
                     AVVVLRRRQPDLPRGFRCPWVPFVPAVGVAFSVWLVSQLDWVTWSRFLGWLVVGLVLYA
                     GYGYRRSAMSGTPRK"
ORIGIN
        1 cgccacgcaa gccagtcaga cttatcttga agtaggctgc ctacctatga gggcagatgc
       61 ggttcgaggc catctcgacg ggttgctgtt ggcagtactg gaaaccgggc ccctgcacgg
      121 gtacgcgatc atctcgacga tccaggagcg cagcggcggc gcgctggagc tgccgacggg
      181 cacgatctac ccggcgctga accggctgga gcggctcggc ctgctcgaca gcagctggca
      241 gtccgtcggc gaacggcggc ggcggtgcta ccagctcacc gacgcgggca ggcgcagcct
      301 cgacacccaa cgcggcgcgt ggcgcgagtt caccgccacg atcagcgcgg tgctcaaccc
      361 cgccccggcg ccgaggacgg cccgatgacc accgtcgaac gcaggaccga cccggtggac
      421 gactacctcg ccgcgctggc ggccgcggtg cacgggcccg cgaaggtcaa ggccaggatg
      481 ctcgaagaga tccggggcgg gctcgaagac gccgtgtcgg cacagggcgg cgattctcac
      541 gcggccgcgc tcgcgctgcg cgatttcggc accgtcgagg aggtcgcgtc gagctgccag
      601 accgaactga ccatcgcgca gaccaggcac acctcccgcg cgctcgcgct gaccgtgccg
      661 ttcctgctcg cctgctggta cctgatccgg accgcgagcc ccagcggtga cgggcaggtg
      721 gcgcgcgtgg cccagctggt cgcggcccac ctgaccggtg ccgcgaccat cgccgcggtg
      781 ctcgccgcgg cggcgctggc cgccaccggc accctggccc gctggctgcc gaccccgccg
      841 aagctgccgc gcgtggtcgc ctggaccagc acgtccaccg gggccgccat ggcggtggcc
      901 acggtcgcgc tgctctccgc ctcaccggcg tcggcgaact ggccgctggt cgtgctcgcg
      961 gggctgttca ccgccgcgtc gcacgcgatg gtggcgggct cggcgcgcgc ctgccgcgaa
     1021 tgcgcgcgcc tgacctgctg atttcccgtg ttcgacccca taggtaggct gcctacgctt
     1081 ggctatgtag gctgggtacc tatagccagc ctaggtgttg tggaggggtc atgttcaagg
     1141 tgctgctgtc cgtgcacatc ttcgcggtga tactggtcgt cggaccgatc gccgtggccg
     1201 cgtcgctgtt cccccgctac gcgaagcagc tggccgccga agaaggcgaa gtggccaccc
     1261 gcagcaccgg cgtcgcgacg ctgctgcacc ggatctgccg cggctacgcc gtcgtcggca
     1321 tcgccgtccc cgtcttcggc atcggcgcgg gcgcccacct cggcgtgctc ggcgactact
     1381 ggctgatcgc ctccatgatc ctcaccgccg ccgcggccgc actgctggta ctggcgatcc
     1441 tgcccgccca acgccgcgcg atgaccagcg gctccgtgtc gaaactcgcc atgaccacgg
     1501 ggatcttcaa cctgctctgg gcgatcgtcg tcgtgctcat gatcgtccgc ccaggctcca
     1561 ccaccggaat gcacgggtga gcttggactg acactcggcc atccatgaca tctcggtggc
     1621 tcaaggctgt caaccgagcc acgacgatcg gcccctacgg ttcaggcgta ccattcggcc
     1681 aaacgcatgg tgaggatgtt ccgagagcca gaccgccctt tttgttagcc tgaaacgaca
     1741 tcgaaaaccc gtcatcgctt cgcacggcgt tcatgaacat gtcagcagga cgggaatcct
     1801 tgtcgatatt ccatccgttc ttggtcaacc aggacttcat tgcatcgaaa tatttatcgt
     1861 ggtcggctgg atcaagccct cgtacccaat aatcagcatt gacgtgctta cgcttctcga
     1921 atccaacacc cgagggatca gggcacgcgt tctgctgcac tccgcggtct tccaacatcg
     1981 cttcagcggg cagcgccgac cggagttcgg ccgcgtagtt tcgcgcccga tcctcagctt
     2041 gccgcactgt aatggtagga gtgttttgat cgtttgaagg catgtcgcca cctccacagg
     2101 cactcaagag cagcagaacg gcgatcagca acaatgctga aacaggtccg ggacctaccg
     2161 ttcgacgcat cttagtttcc agcaattacc tgccccattc gacgaagcga ggatgagcgc
     2221 ggctcccagt agtcgctgtg cgaatgaaat gggcttgatg catcagcgtc gaagctctgg
     2281 cctccgaacc agggcatggt cggatccggc cccaacggat cgatgtcgtc tgtattttcg
     2341 gtgtgaaagt tcgtcaggat cggtatcgga tcggtgggtg ccgccgtcga aaatacatgc
     2401 ttgccgacct gatcgggcgg aacattgtcc aagtgaagct ggtccgcgtg acgtacccca
     2461 acccctggac tgccagcgaa taccaaatcg tctgcggcga gaccgtgatc tcgggcagtt
     2521 tgaccgatcg ctgtcgtgcc ataactgtga cctataacgg tggtgtgcgg cggtgtgtgt
     2581 gaagggtcgt tcggatgact cgccagcaat ccagcctgaa aatcatgcag aggccgctcc
     2641 gcgttgtcgg cgaacacgct tcgcggcgag tcgaggataa tgttctgggg tgcgtcgtag
     2701 ccgatccaag tgactaccgc agttgacggt gacccggcat cctgcgcaga gcgaagcatg
     2761 aggtcggaac gagctacctg gtcgccgact tcggccagct tggctcccgt gccggggacg
     2821 aacgtcgcga cattctcagc ttcatcggga ttcccactgg aaacgatagc ttgaccagcg
     2881 ttctcggtat ttacgccaag gaggtaagcc ttctgaccgt tgaccgcgtt ctgcaacctg
     2941 tcttcaatcg acttgattcc accaagtttg ccattgatgt catcgatctg cgatttgagg
     3001 tcctcgtact ccgactggtc gttgagcacg atttctccac cggcggttcg acgcaggccg
     3061 tcgatcttct tttgaacgtc gtcgcactgt ttttgcaaag actctttttg ccgcaccaga
     3121 actctttggt tcgcttcgtc ccggacggca acgggcaccc cgtcgagctt gccgacaatg
     3181 cccggattat ctctggcgta gatcgtttgc cccaccttgg agagggtggc ccaccatgcg
     3241 gcgttctgcg cgggcgtcgc gccgggcggg ggttcgggca gggtgaggcc gatttctttc
     3301 aggcccgcgt cggctgccgc cgcgacggtg ccttggtgga agtcggcgta ttcgccgaag
     3361 gcggcccgga agaagagcga gtcgaggtcg ttgtcgatgt cctcggcggt gcgcagggct
     3421 tgggtgaggt cggcgcccac ctgctcgtgt acgtgggcgc ggtcctccgg gtgcatctcc
     3481 ggaggcggct ctttcccggc gaagtcatcg gtgacctggc cattcgcatc gacggtgaag
     3541 ccgtacttgc gggccagttc ttcggcggct tcgatcgcgt gcttgacggg cgggatggcg
     3601 tcggaagcct gcatcagccc cttgctcacg gcgctggtga ccgcggtcaa cgccatgagc
     3661 cgggtcatca accggttgtg ggttccttgg gcggcgtcgg cggcggggcc ggtccagctg
     3721 gccatcggca tgagacggcc gaagtcgtcg ccggagtgca ccagggtctg ctgacgctgg
     3781 cggagggtgg tggcgatctc gttgaggact tcgggtttcc agttcttcac gtcggcgagg
     3841 ctgaccatca gaacgggcct cccggcgcgt cgctgccagg gatggccccg gccgcggcgt
     3901 ggtcaccggc gacgtaggtg tcggccgcgg tggcgaacgc ggttccgtgc gcctccgccc
     3961 cggtgcacca ttcgatgaac gtcatgctcc acgtgtcgga gtacatcgtc gcgttcgcac
     4021 cggccttcgc gccaggcaac gccccagcga cgccagcgac cggtttcccg cagtccgcgc
     4081 cgcgcagctc cccgagcgcg gactgcgcgg atctgctggt cgcgcgcagc gtttcgggca
     4141 cgcttgtgaa gcccataaaa gccctccccg gctgtatgga tcactacctg taggcacaca
     4201 gtgacacacg atccaccact cgcgcaccca gctccctact cacgggggat gagtagttcc
     4261 ccgcagcgcc gcacgctcgg cgtgcggtgg gagcaagtaa tctcgcgagg caggtgccga
     4321 cgaggaggtc cgggtggtca gggagcaggc tgggcggatt ctggcggcga acctgcgcgt
     4381 gctgcgggag caggcgggca tgtcgctgtc cgagctggcg cggcggtccg ccatcgcgaa
     4441 gggcacgctg tcccagctcg aatcgggcac ggggaacccc acgatcgaca cggtgttcag
     4501 tttgtcgaac gcgttggggg ttccggtttc gagtctgctg accgagcgcg ccgatccgga
     4561 tgtggtgctg gtgcgtggcg gcgggctgga ggtactcagc agcaacgcgg tcgacctgcg
     4621 gatgctccgc cggatggatg tcaccgaaac cgtcttcgag ctgtacgacc agcgggtgcg
     4681 gccaggcgag gtccagcact cggacggcca ccccggccgc gagcacgtcg tcgtcacctc
     4741 cggggtgctc cgggtcggcc cgccggattc gccgttcgag ctgcagcccg gcgactacgt
     4801 gtgcttcccc gcgcagaacc cgcacatcta cgagacgatc ggcgggccgg tgctttcggt
     4861 gctgctgctg gagtatccgg ccgacgcggg gccgccgacg ctcggcggct cctgcacggc
     4921 gggcgagcgg aggggttgac cagggtccac ccggcgactt agtctccggt cgttcatttc
     4981 aatgaacact ggaggtggtc gtggcgcatc ccgacgtggt ggtcgccggt gccggggtga
     5041 tcggtgccgc ctgtgccgag gcgctgagcg cggcggggct cgtcgtgacc gtgctcgatc
     5101 gcggcgcgcc cgcgggcggc accaccgcgg caggcgaggg caacgtgctg gtgtccgaca
     5161 aggagcccgg cccggagctg gacctggcca aggcgtcgcg acggctgtgg ccggaactcc
     5221 tcgaaggact gcgcgcggag ctgggcaccg aactcgccga cgccgagtgg gatcccaagg
     5281 gcggcctcgt cgtctcgacg ggcgaagccg ggccgctgcg ggacttcgcc gccgtgcagc
     5341 gggagtccgg tgtggacgca caggtgatcg gcgccgagga agccgcggag ctggaaccgt
     5401 tgctcaccaa ggagatcacc gccgccgtct ggtatccgga ggatgcgcag ctgcaaccgg
     5461 tgctcgcggc gacgaccctg ctcgccgcag tgcgcgcacg gggcggcacc gtcctttccg
     5521 gacacaccgc gctcggggtg accaccagcg gcgggtcgat cagcggcgtc cgcacgaacc
     5581 acggcgtgct cccgtgcggc gcggtcgtga acgcgtgcgg gccatggtcc ggtgagttcg
     5641 ccgcggcggc gggcgcgccg atcgccgtgc tgcccaggcg tggcatggtg ctggtcaccg
     5701 cgccgctgcc ggaatcggtg cggcacaagg tgtacgacgc ggactacgtg ggcgcggtcg
     5761 cgagcggtga cgcggatctg cagacctcga ccgtggtcga atcgacggcc gcgggcaccg
     5821 tcctgatcgg ctccagccgc cagcgggtgg ggttcgacga aaccatccgg gtcgacgtcc
     5881 tcgcggagct ggcgcgcaag gcggtgacgc tgttcccgtt cctggccgcg gtgccggtga
     5941 tgcgcgccta cggcggattc cggccctacg caccggatca cctcccggtg atcggcgagg
     6001 atccccggct tccggggctc tggcacgcga ccggtcacga gggtgccggg atcgggctcg
     6061 ccgcggcgac cgggcggctg ctcgccgatc tcttccgcgg caacgaatcc attgtggacc
     6121 acaatccgtt ccgagtggac cgggcggagg tgctggcatg aacgtcagcg tggacggcga
     6181 gccgatgacc gccgcaccgg ggcagaccgt ggccgggctg ctcctcgccg ctggccggtc
     6241 ttcgtggcgc agcacccgcg gcggcggcag gccacgcggc gtgttctgcg ggatcggcgt
     6301 ctgcttcgac tgcctggtgg tggtgaacgg cgtgccggac gtccgcgcct gccagcggac
     6361 gctcgccgac ggcgatcgga tcagcaccca gcacggggcg gagctgccgt catgaccgtg
     6421 accgtcgtcg gcgccgggcc cgccgggatg gccgccgcgc gcaccgccgc cgaagcgggc
     6481 gcggacgtgc tgctgatcga ctcgggcacc aagctcggcg gccagtatca ccggcagaac
     6541 tccttgtaca caggggaaaa gttcgcactt ccggcgaacg tgacccacct gccggacacc
     6601 gccgtctggg ccgtggagcc tggaccgcgg ctgcacctgc gcaccggacc agccgacgga
     6661 cccggccgca ccgggcgcac gatcgacgcc gacgcgctcg tgctggccac cggggcgtac
     6721 gaccgcgcac tgccgttccc cggctgggac ctgcccggcg tctacaccgc gggcgccgcg
     6781 caggcgatgg cgaagggcca gcgggtcgcg gtcggccgcc gcgtgctcct gtccgggacg
     6841 gggccgttcc tgttcccggt ggccgaatcc ctgctcggcg tcggcgccga agtgctcggc
     6901 gtgctggagg cgaaccaccc ggtgacgggc tggctcgcga acccgggcgg gctgctcgcg
     6961 ggtgccgcca aggccgccga gctgggccgc tacctcgccg tgctggcacg gcaccgggtg
     7021 ccctaccggc cgcggaccac ggtgctcgcg gcgcacggcg aacaccgcgt ggaggccgtg
     7081 acgacggcgc gggtcgaccg cgactggcgc gtggtccccg gcacggagca gcgcgtcgaa
     7141 tgcgacgccg cctgcgtcgg cttcgggttc ctcccccagc tcgaactcgc cgtcgccgcg
     7201 ggctgcgcgc tgcgcgacgg gttcgtcgac gtggacttca cccagcgcac ctcggtgccg
     7261 ggcgtgttcg cggcgggcga gctgaccggg atcggcggcg cggtgctgtc cgaggacgaa
     7321 ggcaccgtgg ccggggccgc cgccgcgggc gcaccggtcc cccgccgcgc gctgcgcggg
     7381 gtccgtgcgg gacggaggtt cgcggccgcg ctcgaagccg cctacccgat ccgatccggc
     7441 tggcgcgacc ggctcaccgg cgacacgctc gtctgccggt gcgaagaagt cacctaccgc
     7501 gcgctgtgcg acgcggtcga aaagcgcgac gccaccggtg tccgcgcgct gaagctcgtc
     7561 agcagggccg ggctcgggca gtgccagggc cggatctgcg gacgcaccgt cgccgagctg
     7621 accggcaccg aaaccaccgc tttctcgaag cgcccgatcg cggcgccggt ccggctcggt
     7681 gagctggcgg aaatccccaa ggaggacaag aaatgacgca ggaaaagctc gacggggtca
     7741 tcgtggcgac cgcgctgccc tacgccgagg acgcgagcgc gcccgccggg ctgcgggtcg
     7801 acctcgaccg ctacgccgag cactgccgct ggctgatcga caacggctgc cgcggcatcg
     7861 ggccgaacgg gtcgctcggc gagtactcct cgctcacctc cgacgagcgg cgcgcggtgg
     7921 cccgcaccgc gatcgaagcc gtcggtgacg acggcatcgt ggtggtcggc gtgcacggcg
     7981 tcggcgcgca ccaggcgcgc gagtgggccg agaaggcggc cgaggacggg gcgcacggcg
     8041 tgctgtgcct gccgccgacg atgtaccgcg cgaacaccgc cgaggtgatg caccactacg
     8101 agcaggtcgc gggcgtcggc ctgccggtga tggtctacaa caacccgatc gacaccaagg
     8161 tggacctgct gccgccggtg gtcgccgaac tggcgcagct gcccaacgtg gtcgcggtca
     8221 aggagttctc cggcgacgtg cggcgggtgc tggaaatccg cgagctggcg ccggagctga
     8281 ccgtggtcgc cggtgccgac gacgtcgcgc tcgaagcgct gctgatgggc gcgaccggct
     8341 ggttcgccgg gttccccaac gtcttccccg ccgagtccgc gcacctgttc tcccttgccc
     8401 agcaaggaaa actggccgag gcacgcgcgc tgtacgaacc actggtcgcg gcgttccgct
     8461 gggattcgcg caccgagttc gtgcaggcga tcaagcgggg catggaactc gtcggccggt
     8521 tcggcggccc gtgccgtccg ccgagggggc cgctgtccga ggacaagctc gccgcgctcg
     8581 acgccgacat gcgccgcgcg atcgcgcacc tcgccgcgca cccggtggca gcctgaaatg
     8641 cgggcttcga ggtacttctc ggcggtcgat tcgcacaccg agggcatgcc gacgcgggtg
     8701 atcaccggcg gtgtcggcgt ggtccccggc gcgacgatgg ccgaaaagcg cgtgcacttc
     8761 gtggagcatc tcgaccacct ccgcgagctg ctggtgaacg aaccgcgcgg gcacgccgcg
     8821 atgagcgggg cgatcctgca gccgccgacg cgcggggacg ccgactgggg cgtcatctac
     8881 atcgaggtgt ccgggtgcct gccgatgtgc gggcacggca cgatcggcgt cgccacggtg
     8941 ctcgtggaga ccgggatggt cgaggtgacc gagccggtga cgaaggtgcg gctcgacacc
     9001 ccggccgggc tggtggtggc cgaggtcgcg gtcaccggcg gtcgtgcgaa agcggtgacc
     9061 atccagaacg tgccctcgtt ctcgctgcgt ctcgacgcgg aagtggacgt cgaagggctc
     9121 gggacggtcc gatacgacct ggcctacggc gggaacttct acgcgatggt cgcgctggac
     9181 gatctcggta tcggattcga caagtcccaa aaggaccgga tgctcaccgc cggactgtcc
     9241 atcatggacg cgatcaacgc ggcggagaaa ccggtgcacc ccgccgatcc cgcgatcacc
     9301 gggtgcaagc acgtccagtt cgtcgcgccg ggcaaggacg gcagcgacgc gcgcaacgcg
     9361 atggcgatcc accccggctg gttcgaccgc tcgccgtgcg gcaccggcac gtccgcgcgg
     9421 atggcccagc tgcacgcgcg cggtgagctg gcgatcggcg cggacttcgt caacgaatcg
     9481 ttgctgggca ccaggtttac cggcaggctg atcgaggaaa cccgcgtcgg tgggctgccc
     9541 gccgtggtgc ccaccgtgac cggccgcgcg tggatcaccg ggatgggcca gtacctgctc
     9601 gatcccaccg atccgttccc gagggggttc accctgtgac cagagtcgtc tcgacctctc
     9661 cgcagcgccc cgccgacgtg gtggcggact gcccggcgac accagccgag caggtaacca
     9721 ggaccgtcgc ggaaagcctt gcggcacaac gggaatgggc gcggtctgcg gcggccgacc
     9781 gcgctgccgc gctgaccgcg atggcggacg ccgtcgccgg tcaccggcgc gagctggccg
     9841 atctcgtgat ccgcgaggtc ggcaagccga gcaccgaagc gctcggcgaa gtcagccgca
     9901 cggtggccat cctgcggtac tacgcgcagc agtgcttcga gccggtcggc gaaacctacc
     9961 cccgcgccgg cgggctggac ttcaccgtcc ggcggccgca cggggtggcc gggctgatca
    10021 cgccgtggaa ctttccgctc gccatcccgg tatggaaggc ggccccggcg ctggcgtgcg
    10081 gcaacgcggt cgtgctcaaa ccggcgcctg ccgcgaccgg atgcgcgctg cggctggcgg
    10141 aactgttcgc cccgcacctg cccgaagggc tgttctcggt ggtgcccggc ctcggcgacg
    10201 cgggcgcggc gctggtcggt tcggccgacg tcgtgtcgtt caccggctcg ggcgcggtcg
    10261 gccgcacggt ggcggtggcc gcggcggaac gcggggtccc cgcgcagtgc gaaatgggcg
    10321 ggctcaacgc gtcgatcgtg ctgcccgacg ccgatcccga ccgggcggcg gcgcagatcg
    10381 cggcggccgc gatggggttc gcgggccaga agtgcaccgc gaccaaacgg atcctcgtgg
    10441 tgggcgatgc cgcgaacttc gcggacgcgc tggtggcgaa ggtcgaagcg ctcggcgtcg
    10501 gcgatcccgc cgacgagggg gtcgcggtcg gcccggtgat cgacgaggcg gcgcggcagc
    10561 gagtgctggc ggccgccgac ggcaaagtcc tcaccggcgg cgggagcccc ggcggcgacg
    10621 gctggttcgc ctcgccgacc gtcgtcacgg ggctcggcca ggacgcgccg ctcaacacca
    10681 ccgaggtgtt cggcccgatc tgcacgctca ccggggtgtc cactgtggat gaagcactgc
    10741 ggatggcgaa ctccggcacg tacggtctgg tcaccgcctt gtacagcaac gatctcgacg
    10801 ccgccctgtc ctttgtggac cagtgcgaat cgggcatggt gaaggtgaac gcgccgacca
    10861 gcggggtgga cttccacctc ccgttcggcg gcgaaaagga atccgggtac ggcgggcggg
    10921 agcagggcaa ggccgcgctg cgcttctaca gctcgtcccg caccgtccag ctcggctgag
    10981 cgatcggcga acacccctga cgggcatcgg cccgccgggc agtgaagcac gccctggaga
    11041 agggaagaac cgagatggca acgaagccgc tcaccgaccg cggcctgttc cgccgcaagc
    11101 ccatcgacga catcgaagaa cccgtgaacg gcgacaccgg gctgaaacgg gtgatgggca
    11161 cctggcagct caccgcgctc agcctcggcg ggctcgtcgg cgcgggcgtg ttctccctct
    11221 ccggggtggt cgcgaaccag ctcgccgggc cgggcgtgct catctcgttc gtgctcgcgg
    11281 tgctcgccag cgcggcggcc gcgttgtgct acgccgaatt caccagcctc atccccaagg
    11341 ccggatccgc ctacacctac gcctacgcgg tgctcggcga ggtcgtcggc tggctgatcg
    11401 gctgggacct gctgctggag tacaccgcga tcgtggccgt ggtcgcgatc ggcgtctcgg
    11461 ggtacctctc gtacctggtg cagcagctcg gattcgacct gcccgactgg atgctcggcg
    11521 cgccggggac cgggtcgggg caccggatcg acctgttcgc gatgctgatg tgcctgctgc
    11581 tcgcgtggat cctcaaccgg ggagccaaat cctcggccag ggtcgagacc gcgctcgtgg
    11641 tgatgaaggt ggtgctcgta ctcgtcgtgg tcgtcgcggg cgccttccac atcaagggcg
    11701 gcaactacac gccgttcctg ccgtacggga tcggcggggc ggtgacgggc gcggcgacgg
    11761 cgttcttcgc ggtgtacggc tacgacgcga tgagcgcggc cgctgaggag accgacgacg
    11821 cgcgcaagaa gatgccgaag gcgatcctgc tttcgctcgg catcgcgacc gtgatctacg
    11881 tgctggtgtg cgtggtcctg ctcggcatgc agaactaccg cgacatcgac acgcagagcc
    11941 cgttctcgag cgcgctggcc gcggtcgggc tgccgtcgct ggcgatcgtg gtcgcggtcg
    12001 gcgcggtact gggcatcacc acctcgatgt tcgcgaacat gctggcggtg accagggtct
    12061 ggttcgcgat gagccgcgac ggcctgctgc cgaagtggtt cgcgaagacg cacccggtgc
    12121 gcaaggtgcc gagcagggtg acctggatcg tcggggtggt ctcggcgctg atcgcggggc
    12181 tgctgccgat cagggaggcc gcggagctga ccaacatcgg catcctcgcc gcgttcatgg
    12241 tggtctcgat cgcggtcgtg gtgctgcggc ggcggcagcc ggacctgccg cgcgggttcc
    12301 gctgcccctg ggtgccgttc gtgcccgcgg tgggcgtcgc gttctcggtg tggctggtca
    12361 gccagctgga ctgggtgacc tggtcgcggt tcctcggctg gctcgtagtc ggcctcgtcc
    12421 tctacgcggg ctacggctac cggcgctcgg ccatgtccgg cacgccccga aagtgacctt
    12481 cggggcgtta gatgccccga aggtcacttt cggggcgccg gagatggctg cctagtgcgt
    12541 ctggaggtac caccagccga gggcggcaag gccgccgagc acgaccacga tcccgcaggt
    12601 gatcagcagc gtgcgcaggc cgttgcggcg gggccgttcg atcggggcgg tctcctgcgg
    12661 cctgctcggc tgcggtagcc cgaccggctc catcgcgggc ctgctcgggt gcaccg
//
