LOCUS       NZ_CP059997            21119 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1405062
            Orig. end                         :: 1426181
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21119
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11119](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11119)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    341..354
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            1035..2456
                     /locus_tag="HUW46_RS06675"
                     /old_locus_tag="HUW46_01336"
     CDS             1035..2456
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421652.1"
                     /locus_tag="HUW46_RS06675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01336"
                     /product="amino acid permease"
                     /protein_id="WP_215546446.1"
                     /transl_table=11
                     /translation="MSRPRRAERPPGRPAPKARALGLTSATGLVTGSIIGTGVFTMPAV
                     LAGAGTSSLVVLAVIAVGAALLAVLFGQLTRRIPDADGGLYAYARHEFGDFAGYLTGWC
                     YWVSAWAGNAAIVSSWVLYVDSLFGIRAPSPWVNWGIALAGLWLPAAVNLAGVRKTAWF
                     ENATVVLKFVPLLFVGVVGWFFASGKNFGAFNTTGGSLYNAIGIAAGVALFAFIGVEVA
                     AVTAKRVRRPERNVGRASLLGTALSAVLYLASSAAVMGLVPHETLVSSETPFVPAFEAI
                     LPGAGWAGTLVAALAVVSGIGALNGWTLVTAEISRAAAKDGLFPRAFAWSDRRGTAWFG
                     VLVAATLPSLLMLWRYTGDSGLAVFTFLVNLAVVTVAIPYFFSACAQLTHLLSRRHPVR
                     RLLLARDLAITGTGVLFSLWVTFAAGYAAVYQAMVVVLAGLIGYAFLKAARERHRETGA
                     PASIRPSDGEQPRAA"
     gene            2480..3721
                     /locus_tag="HUW46_RS06680"
                     /old_locus_tag="HUW46_01337"
     CDS             2480..3721
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659902.1"
                     /locus_tag="HUW46_RS06680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01337"
                     /product="arginine deiminase"
                     /protein_id="WP_215546447.1"
                     /transl_table=11
                     /translation="MSFTVASEVGRLRQVVLHRPGAELDRLTPRNIGRLLFDDVMWAKK
                     AKEEHDVFAETLREQGVRVHYFGTLLAETLETAEGRAFVLDRVCTPRLAGPALAGPLRR
                     LFDGLDGTDLAAALIGGVVKAELPTLRTGSLTWRTLLPEDFVVPPLPNHLFPRDSSCWI
                     YRGVSVNPMAKPARRRETLHTMAIYQHHPMFAGTELTTYHEDGDTDPFPATIEGGDVHV
                     LGNGAVLIGLGERTTPMAVELLSRKLFASGQAHTVLAVEIPRSHATMHLDTLMTMVDRA
                     TFVRYPYLDRKPRSWTVTAGPEPGALDVRPNRDFRGTLAEVLGVGEVTVLSTDEDVRAA
                     EREQWDDGNNYLAISPGVVIGYDRNVATNTMLRKHGIEVITVPGAELGRGRGGPRCMSC
                     PIEREPASTAGGTP"
     gene            3718..4731
                     /gene="argF"
                     /locus_tag="HUW46_RS06685"
                     /old_locus_tag="HUW46_01338"
     CDS             3718..4731
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659901.1"
                     /locus_tag="HUW46_RS06685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01338"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_215546448.1"
                     /transl_table=11
                     /translation="MNLQGRNLLKETDLTRDEFLHLVELASLLRQEKRDGKRPERLAGR
                     SIALVFEKSSTRTRSGFEVAAHDEGAHLTYLGPGESHLGHKESIKDTARVLGRMFDGIE
                     FRGSSQEAVELLGAHAGVPVWNGLTDTWHPTQMLADVLTMRDHANKPLEDVGYCFLGDG
                     RGNIANSLLVTGALLGLDVRICAPTTRWPAREVRTLADALARDSGANAVVTSDVPEAVR
                     GVDFVYTDVWLSMGEPEESWGPRIDQLLPYQVTAEVLGATRNPAVKFLHCLPALHDRDT
                     EIGRRLGERYGLDGLEVTDEVFESPASVVFDQAENRLHTIKAVMVATMSSLGPVAS"
     gene            4728..5630
                     /locus_tag="HUW46_RS06690"
                     /old_locus_tag="HUW46_01339"
     CDS             4728..5630
                     /EC_number="2.7.2.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659900.1"
                     /locus_tag="HUW46_RS06690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01339"
                     /product="carbamate kinase"
                     /protein_id="WP_215546449.1"
                     /transl_table=11
                     /translation="MKIVVALGGNALLERGEPPESLIQERHVLTAATALAPLARQHQLI
                     ITHGNGPQVGMLAVESENDPGVARPYPFDVLGAQTQGMIGYWLVQTLQNAVGRPTACLL
                     SRTVVSPDDPAFASPAKFVGPVYSEAEAFRTAAERDWTVRLDGAAWRRVVPSPEPLDIV
                     ELPLVKLLAEAGTTVVCAGGGGIPVVADDRGLRGVEAVVDKDLTAALLARETGADALLL
                     LTDVDAVEDGYGTPAARPLHRVTSGELRARSFPAGSMGPKITAACRFVDGGGRFAAIGR
                     LDAAEDLIAGTSGTIVRAR"
     gene            5840..6268
                     /locus_tag="HUW46_RS06695"
                     /old_locus_tag="HUW46_01340"
     CDS             5840..6268
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_01340"
                     /product="hypothetical protein"
                     /protein_id="WP_215546450.1"
                     /transl_table=11
                     /translation="MNDRAPFPGHRRACEYCGSLIPLDQSASALVPDSSVLDPEDPSGD
                     GQRQITACGSAHLDALIERARAAWIPEQRWFGELCRASTRPGATGATMAELGARARMPA
                     EHVRRAVLWNSRRETPLCALPGGQVLPGADLETTLDNR"
     gene            6315..7424
                     /locus_tag="HUW46_RS06700"
                     /old_locus_tag="HUW46_01341"
     CDS             6315..7424
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016697344.1"
                     /locus_tag="HUW46_RS06700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01341"
                     /product="acyltransferase"
                     /protein_id="WP_215546451.1"
                     /transl_table=11
                     /translation="MTERREVYVDWLRAVSLLVVVLWHWAFTILRWSPTGPHATNPLGF
                     FSGLWIFTWLLQVMPLFFYVGGFAHLASWERARAAGTSLGSYVLSHVKHLVVPATLLAG
                     TWAALGVVLGLLFRLDWIGNAVMLVISPLWFLGVYVALIALLPVSLWLHRRFDLLALVW
                     LGGIALAVDVLRFRYGLSALGWVNMAAVWMLAHQAGFFYRRLVDAPRRLDLSLLWAGLF
                     ALAGLVFSGLYPGSMVGVPGDRWSNMAPPTFVIVALLAFQIGFAEVIRPSMERRLARPR
                     WHRFTELMNRFALPLFLFHTTGMAMARALDYFVFEGAIVDDRAPDLIWWLQRPLAVLGP
                     LLFTAPVIALFLWYHRKRAPKGEPRDTAS"
     gene            complement(7428..8261)
                     /locus_tag="HUW46_RS06705"
                     /old_locus_tag="HUW46_01342"
     CDS             complement(7428..8261)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227389.1"
                     /locus_tag="HUW46_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01342"
                     /product="slipin family protein"
                     /protein_id="WP_215546452.1"
                     /transl_table=11
                     /translation="MNAWVVIGIVAVVALLLGLSVRVVKQYEQGVLFRLGQVRGVRMPG
                     LRLIIPVVDVLHRVSLRIITLPIQSQGIITRDNVSVDVSAVAYFRVVDAVKSVVAIENV
                     YAAIDQIAQTTLRKVVGQHTLDQTLAETDQINVDIRKILDMTTVEWGVEVTLVELKDIQ
                     LPESMKRAMAKQAEAEREKRAKIINAQGESLAADALGDASDTMMAHPLALQLRNLQTLV
                     ELGVDKNTTVVFPAPLMSTIGELGTFLSREAASASEAPPRQRGVTTATEPVAAPR"
     misc_feature    complement(8471..8491)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.31"
                     /tool="antismash"
     gene            8482..8892
                     /locus_tag="HUW46_RS06710"
                     /old_locus_tag="HUW46_01343"
     CDS             8482..8892
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_01343"
                     /product="hypothetical protein"
                     /protein_id="WP_215546453.1"
                     /transl_table=11
                     /translation="MTKPDPYPSGNPFPENEKPPPRLVYPDSARWVRARRVQLGCTAIH
                     IVCGLFAVVLLAHVVFVAGGANQANGVASIVRAWSHAVSLGFEGLFTPPSPGWRAFLND
                     GLAAVTWVVVSAVATTLLRRIALAPGDDEMTR"
     gene            complement(8903..9394)
                     /locus_tag="HUW46_RS06715"
                     /old_locus_tag="HUW46_01344"
     CDS             complement(8903..9394)
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639738.1"
                     /locus_tag="HUW46_RS06715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01344"
                     /product="universal stress protein"
                     /protein_id="WP_215546454.1"
                     /transl_table=11
                     /translation="MAAGDRKDVIVVGVDGSQASAAALRWAVREAALSHRGVHVVRAWT
                     FDPLPGPGTGLSRQRAEADRRRELDHLVADVRGETSPVEVVAKVVEDTPSAALGRASDG
                     AAMLVLGSHGHNRVLRLLVGSVTEQCLRAATCPVVVIPARTRAPRPPESGTEPLTGPLL
                     "
     gene            9578..9985
                     /locus_tag="HUW46_RS06720"
                     /old_locus_tag="HUW46_01345"
     CDS             9578..9985
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012780.4"
                     /locus_tag="HUW46_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01345"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_215546455.1"
                     /transl_table=11
                     /translation="MLVRDIMSTPTIAITSDASIAEAAATMASRGFTSLPVTDREGRLL
                     GLLTEADLVGGITAAGEGRSDPDTGVMLTHRPHLVAALMRPSPVVTGPGIDVVDLAETM
                     VARQVRSVPVLADGKLVGIVTLQDLVRVLAS"
     gene            complement(10001..11119)
                     /locus_tag="HUW46_RS06725"
                     /old_locus_tag="HUW46_01346"
     CDS             complement(10001..11119)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635413.1"
                     /locus_tag="HUW46_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01346"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_215546456.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.3e-44, bitscore:
                     150.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIVIAGGGLSGATLAAHLAAEPRVTDEVTVVDDGRSPFSEAGWA
                     YWSDRPGLLSGAVSRTFDCFRVHAGGRDRTLGLGRYRYHRVRGTDFAAEVERLIGAHGG
                     VTFRRGRVERVGDGELVVDGERWEADWVFDSVAGPRTPPPADARLVFRGWHLRSEEPVF
                     DPEVVTFADFRTAQDLAASFVYVLPRSPAEALVELTSFTAPEHHVAPEPRQQRAALAEY
                     LEQIVGTDRYTVLREEGAALPLTAAPAKRRSGRTMAIGTKAGLAKASTGFAYQRIQRDS
                     AAIVRSLRTRGHPFAVPAGAARYRWFDGALLDVVVREPARLEQTFAALFDRGSAEPVLR
                     FLDEASTPWQDGILFAGLPTGLFAAAVARRAR"
     gene            complement(11152..11751)
                     /locus_tag="HUW46_RS06730"
                     /old_locus_tag="HUW46_01347"
     CDS             complement(11152..11751)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_01347"
                     /product="hypothetical protein"
                     /protein_id="WP_215546457.1"
                     /transl_table=11
                     /translation="MDASRRILVRLWRTFKPGADSLARPSDRFQASVLVLFILFALAAV
                     PFAASIGSETHARQAEQAREQVQTRYQSTATLLTDGPALSATGRSASVGGEKPTEATWT
                     LPNGVPRFGKVPAEEGALKGAVVPVWLDRDGNPVDAPITEFGAVVDGIAAGAGSWLGLC
                     LTLLGIYGLTSLGLNRARLARWQWEWDREQDRKTRF"
     misc_feature    complement(11771..11785)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    11772..11783
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            complement(11916..13505)
                     /locus_tag="HUW46_RS06735"
                     /old_locus_tag="HUW46_01348"
     CDS             complement(11916..13505)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635387.1"
                     /locus_tag="HUW46_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01348"
                     /product="ABC transporter permease"
                     /protein_id="WP_215546458.1"
                     /transl_table=11
                     /translation="MNALTGTRMLIRLALRLDRIRLPLWIGVFVVVAAASAAATVALYP
                     GAADRAAIADSVNSVPAMLALYGPVYAPTAGATAVFKLGGFGAALVGLLMILTVVRHTR
                     AEEESGRLELVGAAVTGRSAALAAALTVVSAASLVLGLVTAFGLVAAGLPWAGSFAFGL
                     GWAVTGLAFGSLAAVTAQLTRGARTASGLAAAALVVAYVLRAVGDATGNAWLSWLSPIG
                     WAHQLHAYAGERWWVSLLSLGFAAACAGAARRLAHRRDFGAGLLADRAGPERADRLLRG
                     SWGLTWRLNRMALGVWTACFLALGVVIGNLAGGVSRFLDTPKARQLIAALGGESGVTDS
                     FLAAEFAIFGVLVSVYAVWVVVRLGQEEHALRLDPLLAGAVGRARVLTGYLLTAGAGSA
                     LPLVAAGIGAGIGNGLRSGDVTGEIARLTGAAVSRLPAVWVLAALAFAVFGLAPRAVAW
                     MWGVLAGFVVIGDFGPLLGLPAWVVDLSPFTHLPRLPGAAVSVTPLLWLVMAAVALFLL
                     GLTAFRGRDVAT"
     gene            complement(13502..14416)
                     /locus_tag="HUW46_RS06740"
                     /old_locus_tag="HUW46_01349"
     CDS             complement(13502..14416)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100562.1"
                     /locus_tag="HUW46_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01349"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_215546459.1"
                     /transl_table=11
                     /translation="MTDQERPAIEITGLSKAFGTVQALDGLDLTVRAGEVHGFLGPNGA
                     GKSTTIRVLLGLLRADSGQVRLLGGDPWRDSVLLHRKLAYVPGEVSLWPNLTGGETIDL
                     LGRLRGGLDPKRRARYLELFDLDPTTKAVAYSKGNRQKVAVVAALASDVDLLLLDEPTA
                     GLDPLMDQVFRDCVREERERGRTVLLSSHILAEAEALCDRVSIIRHGRNVDTGSLDELR
                     HLTRTTITARVSRVPDELRALPAVHDLSVDGDQVRMSVDSAGLDGVLGALSHVGVRSVT
                     SRQPTLEELFLRHYRRDTAEASV"
     gene            complement(14413..16677)
                     /locus_tag="HUW46_RS06745"
                     /old_locus_tag="HUW46_01350"
     CDS             complement(14413..16677)
                     /EC_number="7.2.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015662 - P-type ion transporter activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658858.1"
                     /locus_tag="HUW46_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01350"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_215546460.1"
                     /transl_table=11
                     /translation="MRAVRLARSREAVLLVAVTLLVGTGGVLSLVGGGGAKVLWAAATV
                     VALGPSVVWVMADLRARRWGADLLAVLALAATLPVGEYLAGGIVALMVATGHVLEAGAR
                     RRAGRDLSMLLDRAPSRTHRRTADGLETIGVDEVVAGQAIVVLPGEVVSVDGVLDADGA
                     FDESALTGEPLPVPKRAGATVHSGTVNAGAAVDLVATAAAGESTYAGIVRLAERAVAGT
                     APVARIADRIAIWFLPVALLMAAAAWLFTGDAVRAVAVLVTATPCPLLLAVPIAVTAGM
                     SRMSRAGVVVKDGAALETLGNVRVLLLDKTGTVSEGRPEVTDVVCAPGMTEERVLALAA
                     SVERLSPHVLAAAIVRAAAAAGVPVERAQDVTETPGTGVRGVVDGRRVTVGRLPGERDL
                     PGWARGVLNRGKLDLASVVWVDVDGALTAAFLVRDRVRRDAPRTMKRLREAGIREIRLV
                     TGDRVDNAREVAATLGLDAVTAEVGPAEKVTSAENACRAGVTAFVGDGVNDAPALATAD
                     VGVAMGSYGATAATQVADAVILDDRLERLADAVETARRSRTLAVWSAVGGTVLSLGAMA
                     AAASGLLLPVAGAVVQEAIDVVAILNALRALRGRTRRHDPRADELAARFSAEHERLAPA
                     RAAIRHAADALADGPTAASDAAVRRANRMVVERLLPHEVAEESELYPVLGAVRTAALSR
                     EHAEISRLSRRLGRHLAVAPGRIGADQVDDLRATLYGLDAVLNLHYAQEEEAFFSGKED
                     R"
     gene            complement(16677..17321)
                     /locus_tag="HUW46_RS06750"
                     /old_locus_tag="HUW46_01351"
     CDS             complement(16677..17321)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227301.1"
                     /locus_tag="HUW46_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01351"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_215546461.1"
                     /transl_table=11
                     /translation="MTSLTVSTVMTPDPVTVRTDTPLKEIAEVLTARAISAVGVLDRHG
                     ALVGVVSEADLLSHLREHERPSWLAKRLSRRDRRMSGRVASDLMTAPALTIDAGASLTA
                     ASAEFARTGVRRLFVLRRGALVGVVSRSDLVRVFVRTDDELLHEVERGVLLRALGLGPD
                     RARVAVHDGVVTMCGRVEKRSEVETLTRMVEDVPGVVAVENRLDYVWNDVA"
     gene            complement(17438..18442)
                     /locus_tag="HUW46_RS06755"
                     /old_locus_tag="HUW46_01352"
     CDS             complement(17438..18442)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004024 - alcohol dehydrogenase activity,
                     zinc-dependent [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240336.1"
                     /locus_tag="HUW46_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01352"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_215549713.1"
                     /sec_met_domain="ADH_N (E-value: 4.2e-28, bitscore: 96.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAWRVTRPGPMVSRPLDQVTAPVPVPGPGELLVRVLVCGVCRTD
                     LHVAEGDLAVHRRGVTPGHEVVGEVVAIGDGPATGFAIGDRAGIAWLRGTCGRCRYCAR
                     GRENLCPDSVYTGWDADGGYAEFAVVPAGYALRLPDGYTDDELAPLLCAGIIGYRALLR
                     AEVPERGVLGIYGFGGSAHLTAQVAIARGVTVHVMTRSAAARRLALELGAASATGAGDS
                     PPEPLDSAILFAPVGDLVLPALAALDRGGTLAIAGIHLSDIPPLRYQRHLFQERQVRSV
                     TANTRADAEEFLGVAGSHRLRVSTSPYPLAEADRALSDLAADRVNGAAVLRVN"
     gene            18590..20485
                     /gene="ftsH"
                     /locus_tag="HUW46_RS06760"
                     /old_locus_tag="HUW46_01353"
     CDS             18590..20485
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658854.1"
                     /locus_tag="HUW46_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01353"
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="WP_215546462.1"
                     /transl_table=11
                     /translation="MSRTAAPGPPPSAPPPATEPPKRGWPWWLTSLLVLVYLAILFGPA
                     LLERGTSAVPYTEFLSKVDQGQVDSVTVDDHGSLSGELRGGAGFTSQVPTALNDASLEP
                     LLRSKNVKITAKTTTTSWVSTLTAFLPFALFLGLMIWIGRRVRRSLADGGGVGGLGGIG
                     GIGRSKAKIIEAQRPTTRFADVAGYEGVKQEVSEVVDFLRDPTRYAAAGAKGPRGVIMI
                     GPPGTGKTLIARAVAGEASVPFLSITGSAFVEMFVGVGASRVRDLFDEARNRAPSIIFI
                     DEIDAVGSRRGPGGFGGHEEREQTLNQLLSEMDGFDQSSGIVVLAATNRPETLDPALLR
                     PGRFDRQVTVPLPNQAERAAILTVHIDGKHLAPDVDLTVVARGTPGFSGADLANLVNEA
                     AINAVRDDRTVLTAADFATARDRVLLGRRDASNALLPEERESVAVHESGHALVAALCEH
                     ADPVTKVTILPAGMALGATEQLPEAERRLYREDYLSDLLAVRMGGRAAELVVFGQGSTG
                     AANDLAEATALAVKMVTEFGLSPALGPIGYGTGAHAAPVDPVEAAQRPYSEHTQRTIDQ
                     EVARLLAEAEARAVAMLTSRRDALDRLAAQLREQETVDGDAVLAALRETTAAPAR"
     gene            20599..20862
                     /locus_tag="HUW46_RS06765"
                     /old_locus_tag="HUW46_01354"
     CDS             20599..20862
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014467266.1"
                     /locus_tag="HUW46_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_01354"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_215546463.1"
                     /transl_table=11
                     /translation="MPNWWYHACGGTGWFGPAIGLGIVLIAGIVLLAIALVRRGSKPQA
                     PDPTAMHVLEERFARGEIDTEEFEQRRDILRRAAENGTRRTR"
ORIGIN
        1 gacgaagaca ccggcacgtt ttcgcgatcg tcaccggaat cgccgcgcta atcgcgctga
       61 cgctttcgac agcggaagca accccgcgag cagctcatcc gtaccacacc accgcggatt
      121 cggcgatcga ccagcgctac tcggcggaac cggctttgcg ccagttgctc ggcccggcga
      181 ccgcggccga acaaaccgac ggcaccatcc actaccgcac ctatcagtac gggaacctgt
      241 actacacgcc cgccaccggc gtgcacgagg tgcacgggag cattctgacc gcctactacc
      301 gggaagggca ctaccagaag ttcggcgtgc cgaccaccga cgaacaaccg tgcgccgatc
      361 ccgccgggcg gcacaacatc ttccagctca ccgccgcgac cggcgccacc acgacctccg
      421 gattctactg gcgcgaggat ctcggcgcgc attccatcgt gggcgcggtg ttcacgaaat
      481 gggcggcggc agggtacgag tggggcctct acggataccc cacgagtgac acctacagta
      541 ccgccaccgg agccacgttc aaccatttcc tcggtaacga caaggccggt gcttccattt
      601 acgtgaccgc gctggcgggc gcgaacggcg tcaagggccg aatccgcgac cgctggatct
      661 ccctcggcgg cgaatactcc tacctcggct atccggaatc cgacgagttc accgtgaccg
      721 gcggaaagcg cagcaacttc cacggcggct acatcacgtg gatggcgcag accgggcaga
      781 cggcggtgta ccgctactac tgacgatccg gcccggcgcc gggtatccgg gacgggtccc
      841 tcccaccgcg aagacgcgga gtgcggaggg gcccgcctca ccatgcgcag ccccggacga
      901 gacgacgcgg acacccggcc gctccttgat gaccttcgtc ccctcctgga ctcccgatcg
      961 gccctgcgtg cgcaccaccg cgccccggtg tgatggacac ggccacccgc ggccacgtca
     1021 ggaggtagcc agccatgtcc cgtccacgcc gagcggaacg cccaccgggc aggccggcac
     1081 cgaaggcacg cgcgctgggg ctgacctcgg ccaccgggct ggtcaccggc agcatcatcg
     1141 gcaccggggt cttcacgatg cccgccgtgc tcgccggtgc gggcacgagc tcgctggtcg
     1201 tgctcgcggt catcgcggtg ggcgccgcgc tactcgccgt ccttttcgga cagttgaccc
     1261 ggcggatacc cgacgccgac ggcggtttgt acgcctacgc ccgccacgag ttcggcgact
     1321 tcgccggcta cctcaccggg tggtgctact gggtgtcggc atgggcgggc aacgccgcca
     1381 tcgtgtcctc gtgggtgctc tacgtcgatt cgctgttcgg tatccgcgct ccgtcgccgt
     1441 gggtgaactg gggaatcgcg ctcgccgggc tgtggctccc ggcggcggtc aacctggccg
     1501 gagtgcggaa gacggcgtgg ttcgaaaacg ccaccgtggt gctcaagttc gttccactgc
     1561 tcttcgtggg cgtcgtcggc tggttcttcg cctccgggaa gaacttcggc gcgttcaaca
     1621 ccaccggtgg cagcttgtac aacgccatcg gcatcgcggc cggggtggcg ttgttcgcct
     1681 tcatcggggt cgaggtcgcc gcagtcaccg cgaaacgggt gcgccgcccg gaacgcaacg
     1741 tcggcagggc ctcgttgctg ggtaccgcgt tgagcgcggt cctctacctc gcgtcgtccg
     1801 cggcggtgat gggcctcgtg ccccacgaaa ccctggtgtc cagcgaaacc ccgttcgtcc
     1861 ccgccttcga agcgatcctg cccggtgccg gctgggcggg caccctggtg gccgcgctcg
     1921 cggtggtctc cggtatcggt gcgctcaacg ggtggaccct cgtcaccgcg gagatctcgc
     1981 gggccgccgc gaaggacggt ttgttccccc gcgccttcgc ctggtccgat cgccgcggta
     2041 ccgcgtggtt cggcgtactg gtggcggcca cgctgccctc gctgctgatg ttgtggcgct
     2101 acaccggcga ttccgggctg gccgttttca cgttcctggt caacctcgcc gtggtcaccg
     2161 tcgccatccc gtacttcttc tccgcctgtg cccagctcac ccacctcctg tcccgccgcc
     2221 accccgtacg gcgcctgctg ctcgctcgcg atctcgcgat cacgggtacc ggcgtcctgt
     2281 tctcgctgtg ggtgaccttc gcggccggat acgccgccgt gtaccaggcg atggtcgtgg
     2341 tgctggccgg gctgatcggc tacgcgttcc tcaaagccgc gcgggaacgg caccgcgaaa
     2401 ccggcgcacc ggcgagcatc cgcccctcgg acggcgagca gccccgagcg gcctgaacga
     2461 acgcggaaag gagatccgga tgagcttcac cgtcgcgtcc gaagtgggcc ggctccggca
     2521 ggtcgtcctc caccggccgg gtgccgagct ggaccggctg acgccgcgca acatcggcag
     2581 actgctgttc gacgatgtca tgtgggcgaa gaaggcgaag gaggagcacg acgtcttcgc
     2641 cgaaacgctg cgcgagcaag gtgttcgggt gcactacttc ggcaccctcc tcgccgagac
     2701 tctggaaacg gccgagggca gagccttcgt gctcgaccgg gtgtgcacac cgcggctcgc
     2761 cgggcccgcg ctcgccggcc cgctgcgacg gctgttcgac ggcctcgacg gcaccgacct
     2821 cgccgcggcc ctgatcggcg gagtggtgaa ggcggaactg ccgacgctgc gaacggggag
     2881 cctcacctgg cgcaccctgc tgccggagga cttcgtggtg cccccgctgc cgaaccacct
     2941 gttcccgcgc gacagctcgt gctggatcta ccgaggcgtt tcggtcaacc cgatggccaa
     3001 accggcgcgg cggcgcgaaa ccctgcacac gatggcgatc taccagcacc acccgatgtt
     3061 cgccgggacc gagctcacca cctaccacga ggacggcgac accgacccgt tcccggccac
     3121 catcgaaggc ggcgacgtgc acgtcctcgg caacggcgcg gtgctgatcg gcctcggcga
     3181 acggaccacc ccgatggcgg tggaactgtt gtcccgcaag ctgttcgcct ccggccaggc
     3241 gcacaccgtc ctcgccgtcg aaatcccccg atcccacgcc acgatgcacc tggacaccct
     3301 gatgaccatg gtcgacaggg ccaccttcgt ccgctacccg tacctcgacc ggaaaccgcg
     3361 gtcctggacc gtaaccgccg ggccggaacc cggcgcgctg gacgtccgcc cgaaccgcga
     3421 tttccggggc acgctcgccg aagtgctcgg agtcggcgaa gtcaccgtcc tgtccaccga
     3481 cgaggacgtc cgcgccgccg aacgcgaaca gtgggacgac ggtaacaact acctcgccat
     3541 ctcccccggc gtggtcatcg gctacgaccg caacgtcgcc acgaacacca tgctgcgcaa
     3601 gcacggcatc gaagtgatca cggtgccggg cgccgaactc ggccgcgggc gcggtggccc
     3661 gcgctgcatg agctgtccca tcgaacgcga accggcctcg accgcgggag gaaccccatg
     3721 aacctgcagg gacgcaacct gctgaaggaa accgacctca cccgcgacga gttcctgcac
     3781 ctggtggaac tcgcttcgct gctgaggcag gaaaaacggg acggcaagcg gccggaacgg
     3841 ctggcgggcc ggtcgatcgc gctcgtcttc gagaagagtt cgacccgcac cagatcgggg
     3901 ttcgaggtcg cagcgcacga cgagggcgcc cacctcacct atctcggtcc cggcgaatcc
     3961 cacctcggcc acaaggagtc catcaaggac accgcacgcg tactgggccg gatgttcgac
     4021 ggcatcgagt tccgcggctc gtcccaggag gccgtcgaac tgctcggcgc gcacgccggg
     4081 gttccggtgt ggaacggcct caccgacacc tggcacccga cccagatgct cgccgatgtc
     4141 ctcaccatgc gagaccacgc gaacaaacct ctcgaggacg tcggttactg ctttctcgga
     4201 gacgggcgag gcaatatcgc caactcgctg ctcgtcaccg gcgccctttt ggggctggac
     4261 gtgcggatct gcgcccccac cacgcggtgg cccgcgcgcg aggtccgcac actcgccgac
     4321 gcactcgctc gcgattcagg ggccaacgcc gtggtcacca gcgacgtccc ggaagcggtg
     4381 cgcggtgtcg acttcgtcta caccgacgtg tggctctcga tgggcgaacc ggaagagtcc
     4441 tggggtccgc gcatcgacca gctcctgccc taccaggtca ccgcggaagt ccttggcgcg
     4501 acgcggaacc cggcggtgaa gttcctgcac tgccttcccg cactgcacga ccgggacacc
     4561 gaaatcgggc gacggctcgg agaaaggtac gggctcgacg gactcgaagt gaccgacgag
     4621 gtcttcgaat caccggcctc cgtggtgttc gaccaggccg aaaaccggtt gcacacgatc
     4681 aaggccgtca tggtggcgac gatgtcgtcg ctcggcccgg tggcgtcgtg aagatcgtcg
     4741 tagcactggg cggcaacgca ctgctggaac gcggggagcc gccggagtcg ctgatccagg
     4801 aacgacacgt cctcacggcc gcgaccgcgc tggcaccgct cgccaggcag caccagttga
     4861 tcatcaccca cggaaacggc ccgcaggtcg ggatgctggc ggtggaaagc gagaacgacc
     4921 ccggcgtggc gcgtccctac ccgttcgacg tactgggcgc gcaaacccag ggaatgatcg
     4981 gctactggct ggtgcagacg ctgcagaacg ccgtgggacg ccctaccgcc tgcctgctca
     5041 gccggaccgt cgtgagcccg gacgatcccg cgttcgcgtc cccggcgaag ttcgtcggcc
     5101 ccgtgtactc cgaagccgag gcgttccgga ccgccgcgga gcgggactgg acggtacggc
     5161 tcgacggggc ggcatggcgc cgggtcgtcc cctccccgga gcccctcgac atcgtcgaac
     5221 tgccactggt caagctcctc gcggaggcgg ggaccaccgt ggtgtgcgcg ggcggcggcg
     5281 gtattcccgt ggtcgccgac gaccgcggcc tgcgcggggt cgaagccgtg gtcgacaagg
     5341 acctcacggc ggccctgctg gccagggaaa ccggagccga cgcactcctg ctgctcaccg
     5401 acgtcgacgc ggtcgaagac ggttacggca ccccggcggc gcggccgctc caccgggtca
     5461 ccagcgggga actgcgagcg cggtcgttcc cggccgggtc gatgggcccc aagatcaccg
     5521 ccgcgtgccg gttcgtcgat ggcggcgggc ggttcgccgc gatcggccgc ctcgacgcgg
     5581 ccgaggacct gatcgcgggt acctccggaa cgatcgtgcg cgcccggtga aacgccgtga
     5641 ccacaccgga tccgccggtc gtccattcca gcgattttcc gcgaagacag cctccgcgcc
     5701 ggacgggcgg aggctaccgt cgaggtggag ttcggccgcc ctggacgcgg ctcgcccgcg
     5761 gacgtccgcg aaccacaccc accgccgccc cagcccccgg tgacgggatc ccgcctgacc
     5821 caggacgtgg agaccagtca tgaacgatcg cgcccccttc ccggggcacc gccgtgcctg
     5881 cgagtactgc ggaagcctca ttccactcga ccagtctgcc agtgcgctgg tgccggattc
     5941 gtcggtgctc gatcccgagg accccagtgg cgacggccag cgccagatca ccgcgtgcgg
     6001 ctccgcgcac ctggacgcgc tgatcgaacg agcccgtgcc gcctggatcc ccgaacagcg
     6061 gtggttcgga gagctgtgcc gcgccagcac gcggccgggg gcgaccggcg cgacgatggc
     6121 ggaactcggc gcccgcgcgc gcatgcccgc cgagcacgtc cgccgcgccg tgctctggaa
     6181 ctcccgacgc gaaaccccgt tgtgcgccct tccgggcggg caggtccttc ccggggcgga
     6241 tctcgaaacc acgctcgaca accggtgacg cggcccgccc gcttcggccg cttccggaac
     6301 agagggggtg cccgatgacc gagcggcgcg aggtctacgt ggattggctg cgcgcggtca
     6361 gtctgctcgt ggtcgtgctg tggcactggg ccttcaccat cctgcggtgg tcgccgacgg
     6421 gcccgcacgc gacgaacccc ctcggtttct tcagcgggct ctggatcttc acctggctgc
     6481 tccaggtcat gccgttgttc ttctacgtcg gcgggttcgc acacctcgcg tcgtgggaac
     6541 gcgcccgcgc ggcgggaacc agtctcggct cgtacgtgct gagccacgtg aagcatctgg
     6601 tcgtcccggc gaccctgctc gccgggacct gggcggcgct cggcgtcgtg ctgggcctgc
     6661 tgttccggct cgactggatc ggcaacgcgg tgatgctggt gatcagcccg ctgtggttcc
     6721 tcggcgtcta cgtggcgctg atcgcgctcc tgccggtgag cctgtggctg caccgccgct
     6781 tcgacctgct cgcgctggtg tggctcggcg gcatcgcgct cgccgtcgac gtcctgcggt
     6841 tccggtacgg cctgtccgca ctgggctggg tgaacatggc ggcggtgtgg atgctcgccc
     6901 accaggccgg gttcttctac cgcaggctgg tggacgcacc gcgcaggctc gacctctcgt
     6961 tgctgtgggc ggggctgttc gccttggccg ggctggtgtt ctccgggctg tacccgggtt
     7021 cgatggtcgg ggtgcccggc gaccggtggt ccaacatggc accgccgacc ttcgtcatcg
     7081 tggcgttgct ggcgttccag atcggcttcg ccgaggtcat ccggccctcg atggaacgaa
     7141 ggctcgcccg gccgcggtgg caccggttca ccgagctgat gaaccggttc gcgctgccgc
     7201 tgttcctctt ccacaccacg ggaatggcga tggcacgggc cctggactac ttcgtgttcg
     7261 agggcgcgat cgtcgacgac cgcgcccccg acctgatctg gtggctccaa cggccgctgg
     7321 ccgtgctcgg cccgttgctg ttcaccgcac cggtgatcgc gttgttcctg tggtaccacc
     7381 ggaagcgggc tccgaaggga gaaccgcgcg ataccgcgtc gtgaggatca gcgcggcgcc
     7441 gcgacgggtt cggtggccgt cgtgacgcct cgctgccgcg gcggtgcttc cgacgccgac
     7501 gcggcttcgc gggacaggaa cgtacccagc tcgccgatcg tgctcatgag cggcgcgggg
     7561 aacaccaccg tggtgttctt gtcgacgccg agttcgacca gcgtctgcag gttccgcagc
     7621 tgcaacgcca gcgggtgggc catcatcgtg tccgacgcgt cgccgagcgc gtcggccgcg
     7681 agagactcgc cctgtgcgtt gatgatcttc gcgcgcttct cccgctccgc ttcggcctgc
     7741 ttggccatcg cccgcttcat cgactccggc agctggatgt ccttcagctc caccaaggtc
     7801 acctccacgc cccactcgac cgtggtcatg tcgaggatct tgcggatgtc gacgttgatc
     7861 tggtcggtct ccgccagcgt ctggtcgagg gtgtgctgcc cgaccacttt ccgcagtgtg
     7921 gtctgcgcga tctgatcgat cgccgcgtac acgttttcga tcgccaccac ggacttcacc
     7981 gcgtcgacca cgcggaagta cgcgacggcc gacacgtcga cgctcacgtt gtccctggtg
     8041 atgatcccct gcgactggat cggcagcgtg atgatccgca gcgagacccg gtgcagcacg
     8101 tcgaccaccg ggatgatcag ccgcaagccc ggcatccgca ccccccgcac ctgtcccagc
     8161 cggaacagca cgccctgttc gtactgcttc accacccgca ccgacaagcc gagcagcagc
     8221 gccaccacgg cgacgatccc gataacgacc cacgcgttca tgacaggact tcccttcccg
     8281 gaaatgagtg acgtcaacga ttcgccggtc ccgcaccatc ggacaccagc accggcgcgg
     8341 gcaccagagg gcaagggact tccagaccag ggaccaaata cccccgcatc gagtgagcaa
     8401 ggctgcggcg cgaacccgcc gtcgcgcgca tgctgccagc agcgaccggt gtcccgccgg
     8461 aaggtcggag gaatcgacat catgacgaaa ccagatccct atcccagcgg caatccgttc
     8521 cccgagaacg aaaaacctcc ccccaggctc gtgtacccgg attccgcgcg gtgggtccgg
     8581 gcccgccggg tgcagctcgg ctgcacggcg atccacatcg tctgcggcct gttcgcggtg
     8641 gtactcctcg cccacgtcgt attcgtggcc ggtggcgcga accaggcgaa cggcgtcgct
     8701 tcgatcgtcc gtgcctggtc gcacgcggtg tccctcgggt tcgaagggct gttcaccccg
     8761 cccagccccg gctggcgggc cttcctcaac gacggcctcg cggcggtcac ctgggtcgtg
     8821 gtgagcgcgg tcgccaccac gctgttgcgc cgcatagccc tcgcgcccgg ggacgacgag
     8881 atgacccgat gatccgaccg gctcacagca gcgggccggt gaggggctcc gtcccgctct
     8941 cgggcgggcg cggcgcgcgg gtgcgggccg ggatcaccac caccgggcag gtcgccgcgc
     9001 gcaggcactg ctcggtgacg gagccgacga ggagccggag gacccggttg tgcccgtggc
     9061 tgcccaacac cagcatcgcg gcaccgtccg aagcacgtcc gagcgcggcg gacggggtgt
     9121 cctcgacgac cttggcaacg acctcgaccg gtgacgtctc accgcggaca tccgcgacga
     9181 ggtgatcgag ttcgcgtcgc cggtcagctt ccgcgcgctg ccgcgagagg ccggtaccgg
     9241 ggcccggcaa gggatcgaag gtccacgcgc ggaccacgtg gaccccgcgg tggctcagtg
     9301 ccgcctcgcg gacggcccag cgcagcgccg ccgcactggc ctgcgatccg tcgacaccga
     9361 ccacgatcac gtctttccgg tctccggcag ccatcggttc cgcccttccc tcggggtttc
     9421 ttcgcaggct cctccgtgga cgcgtgttcg gtacagggtc cggagttctt ccgatcggtg
     9481 ccggtggaga gccgcaccgg tgaccttgtg ctctcgcaag gtgggttcgc aggcgcgatc
     9541 gtgaaggcac ggccaagacg acacaaggag gcccgcgatg ctggtacgcg acatcatgag
     9601 cacaccgacg atcgcgatca cctcggacgc ctcgatcgcc gaagcggccg ccacgatggc
     9661 ctcccgcggg ttcaccagtc tcccggtgac ggaccgggaa ggcaggctcc tcggcctcct
     9721 gaccgaggcc gatctcgtcg gcggcatcac ggcggcgggg gaagggcgga gtgatcccga
     9781 caccggggtc atgctcaccc accggccaca cctggtcgcc gccctgatgc gcccctctcc
     9841 ggtcgtgacg ggcccgggga tcgacgtcgt cgatctcgcc gaaaccatgg tcgcccgcca
     9901 ggtccggtcc gtgccggtcc tggccgatgg caagctcgtc ggcatcgtca cgctccagga
     9961 cctcgtccgc gtgctcgcga gctgagcgct ggcagcgcgc tcagcgcgcg cgacgggcga
    10021 ccgcggcggc gaagagcccg gtgggaagcc cggcgaagag aatgccgtcc tgccacggag
    10081 tgctggcctc gtcgagaaac cggagcaccg gttcggccga tccgcgatcg aagagcgccg
    10141 cgaaggtctg ttcgagccgc gcgggctcgc gaacgacgac atcgagcagc gcgccgtcga
    10201 accaccggta cctcgcggcg ccggctggga cggcgaaggg atgtccccga gtacgcagcg
    10261 agcgcacgat cgccgcgctg tcccgctgaa tgcgctggta cgcgaagccg gtgctggcct
    10321 tggccagtcc cgccttcgtg ccgatggcca tggtccgccc cgagcgcctc ttcgccggtg
    10381 cggccgtaag cggcagtgcc gcgccttcct ctcgcagcac ggtgtaccga tcggtgccga
    10441 cgatctgttc gaggtactcg gcgagcgcgg cacgctgttg gcggggctcc ggcgcgacgt
    10501 ggtgttccgg tgcggtgaac gaggtgagtt cgaccagtgc ctcggccggg gaccgcggaa
    10561 ggacgtagac gaagctcgcc gccaggtcct gcgcggtccg gaagtcggcg aaggtgacca
    10621 cttcgggatc gaagaccggc tcctcgcttc gcaggtgcca gccgcggaag accagccgcg
    10681 cgtcggccgg tggcggcgtg cgcggcccgg cgacgctgtc gaacacccaa tccgcctccc
    10741 accgctcgcc atccacgacg agttcgccgt cgccgacgcg ctcgacgcgt ccgcggcgga
    10801 acgtgacccc gccgtgcgct ccgatgaggc gttcgacctc ggcggcgaag tcggtgccgc
    10861 gcacccggtg gtaccggtac ctgccgagcc cgagcgtgcg gtcccgtccc ccggcgtgca
    10921 cgcggaaaca gtcgaacgtc cgcgaaaccg cgccgctcag caggccagga cgatccgacc
    10981 agtacgccca gcccgcttcg gaaaacgggg aacggccgtc gtccacgacc gtcacctcgt
    11041 cggtcaccct cggctcggcg gcaaggtgcg cggccagcgt cgcaccgctg agcccgcctc
    11101 ccgcgatcac aatggacacc ggacttcccc ttccgcccgg ggaatccggg ctcagaaccg
    11161 ggtcttgcga tcctgttcgc gatcccattc ccactgccac ctggccagcc gggcgcggtt
    11221 caatccgagt gacgtgaggc cgtagatccc gagcaaggtc aggcacaggc ccagccagga
    11281 accggcgcct gccgcgatcc cgtcgaccac cgcgccgaac tccgtgatcg gtgcgtcgac
    11341 cgggttcccg tcccggtcca gccacaccgg caccaccgca cccttcaagg caccttcttc
    11401 ggcgggaacc tttccgaaac ggggcacgcc gttcggcagg gtccacgtcg cctcggtcgg
    11461 cttctcacct ccgaccgagg cgctccgccc ggtcgccgag agcgccgggc cgtcggtcag
    11521 cagggtcgcc gtgctctggt atcgcgtctg cacctgctca cgtgcctgtt ccgcttgcct
    11581 cgcatgggtt tccgagccga tgctcgccgc gaacggcacc gctgccagcg cgaagaggat
    11641 gaacagcacc agcacgctcg cctggaaccg gtccgatggc cgcgccagcg aatccgcgcc
    11701 cggcttgaac gtccgccaca accgcaccag aatcctccgc gacgcgtcca tggttttctc
    11761 cttcaccagc gggaaatgct ttccaccagc atcgtccgaa cccgcgcgcg tccgaagggt
    11821 cctccggcac cgcccgcccg cgacaggtca cggtgatcga ggactctggg cgagatgccg
    11881 cgggaccaaa gaccctaaag agagtccact gtggatcagg tcgcgacgtc cctgccgcgg
    11941 aaggcggtca gccccagcag aaagagcgcg acagccgcca tcaccagcca caggagtggc
    12001 gtcacggaca ccgcggcacc gggaagccgc ggcaggtgcg tgaacggtga gaggtcgacg
    12061 acccacgcgg gcagcccgag caacggcccg aaatcgccga tgacgacgaa cccggcgagc
    12121 acgccccaca tccaggccac cgcgcgcggc gccaggccga atacggcgaa cgccagcgcg
    12181 gccagcaccc ataccgcggg cagccgggac accgcggcac cggtcagcct ggcgatttcc
    12241 ccggtgacgt cgccggaacg cagcccgttc ccgatccccg cgccgatccc ggccgcgacg
    12301 agcggaaggg cgctcccggc accggccgtc agcaggtacc cggtgagcac ccgtgctcgt
    12361 ccgaccgctc ccgcgagcag aggatccagc cgcagcgcgt gctcctcctg gcccagccgc
    12421 acgaccaccc acaccgcgta gaccgagacc agcacgccga agatcgcgaa ctcggccgcg
    12481 agaaaggagt ccgtgacacc gctttcgccg ccgagcgcgg cgatcagctg ccgcgccttc
    12541 ggcgtgtcga ggaaccggct caccccaccg gcgaggttgc cgatcaccac accgagcgcc
    12601 aggaagcacg ccgtccacac tccgagcgcc atccggttga gccgccacgt gagcccccac
    12661 gagccgcgca gcaggcggtc ggcccgttcc ggtccggccc gatcggccag cagtccggca
    12721 ccgaagtcgc ggcggtgtgc gagccgccga gccgcgccgg cgcacgccgc cgcgaatccc
    12781 agcgacagca gcgaaaccca ccaccgctca ccggcgtagg catgcagctg gtgtgcccag
    12841 ccgatcgggg aaagccagga cagccaagcg tttccggtcg cgtcgcccac cgcgcgcagc
    12901 acgtacgcca ccaccagtgc cgcggcagcc agaccggacg ccgtcctggc accgcgggtg
    12961 agctgtgcgg tgaccgccgc gagcgaaccg aaagcaagcc cggtcaccgc ccacccgaga
    13021 ccgaacgcga aggacccggc ccaaggaagc ccggccgcga cgagtccgaa cgcggtgacg
    13081 agtccgagca ccaggctcgc cgccgaaacc acggtcagcg cggccgcgag cgccgcggac
    13141 cggccggtga cggcggctcc gacgagctcc agccgcccgg attcctcctc ggccctggtg
    13201 tgccggacga ccgtgaggat catcagcaac ccgaccaagg cagcgccgaa gccgccgagt
    13261 ttgaacaccg cggtcgcccc ggccgtcggc gcgtacaccg gtccgtacaa cgccagcatg
    13321 gcgggaacgg agttgacgct gtcggcgatc gccgcgcgat ccgcggcgcc ggggtagagc
    13381 gcgacggtgg ccgccgccga cgcggccgcg accacgacga acactccgat ccacaacggc
    13441 agccggatcc ggtccaggcg cagcgccagt ctgatgagca tcctggtacc ggtgagcgcg
    13501 ttcataccga cgcctccgcg gtgtcgcggc ggtagtgccg caggaacagc tcttcgaggg
    13561 tcggctggcg gctggtcacg ctccgcacgc ccacatggct caacgcgccg aggacgccgt
    13621 cgagcccggc gctgtcgacg ctcatccgca cctggtcgcc atcgacggag agatcgtgca
    13681 cggcgggcag tgctcggagc tcgtcgggca cccgggagac ccgcgccgtg atggtcgtgc
    13741 gggtcaggtg gcgcagctcg tcgagggagc cggtgtcgac gttccgcccg tggcggatga
    13801 tgctgacgcg gtcgcacagc gcctcggctt cggccaggat gtggctcgac agcagaaccg
    13861 tgcggccacg ctcgcgctct tcccgcacac agtcgcggaa cacttggtcc atcaagggat
    13921 ccaggcccgc ggtcggctcg tcgaggagca ggaggtccac atcggacgcc agcgccgcga
    13981 ccacggcgac cttctggcgg ttgcccttcg aataggccac cgccttcgtc gtcgggtcga
    14041 ggtcgaacag ctccaggtaa cgggcgcggc gcttcgggtc gagcccgccg cgcaaccggc
    14101 cgagcaggtc gatcgtctcg ccgccggtga ggttcggcca cagcgacacc tcacccggca
    14161 cgtaggccag cttccggtgc agcagcacgg aatcgcgcca cggatcgccg ccgagcagcc
    14221 ggacctgacc cgagtccgcc cgcaacaacc cgagcagcac ccggatggtg gtcgacttcc
    14281 ccgcaccgtt cgggccgagg aacccgtgca cctcgcccgc gcgcacggtg aggtccagac
    14341 cgtccagtgc ctggacggtc ccgaacgcct tcgacaaacc cgtgatctcg atcgccggtc
    14401 gttcctggtc ggtcatcggt cctccttgcc gctgaaaaag gcttcttcct cttgggcgta
    14461 gtgcaggttc agcacggcgt cgagcccgta cagggtggcc cgcaggtcgt cgacctggtc
    14521 ggcgccgatc cggccgggag ccaccgcgag gtggcgcccg agtcgccggg acagccggga
    14581 gatctcggcg tgctccctgc tcaacgcggc cgtgcgcacg gcaccgagca ccgggtagag
    14641 ctcggactct tccgccacct cgtgcggcag caggcgctcg acgaccatcc ggttggcgcg
    14701 ccggaccgcg gcgtcggagg cggccgtcgg cccgtccgcg agcgcgtccg cggcgtgccg
    14761 gatcgcggcc ctcgccggtg ccagtcgctc gtgctcggcc gagaacctcg ccgccagctc
    14821 gtccgcacgc ggatcgtgcc gccgggttcg cccgcgcagg gcgcgcaacg cgttcaggat
    14881 cgccacgacg tcgatggctt cctggaccac cgcaccggcg acggggagca gcaagcccga
    14941 cgcggccgcg gccatcgcgc ccagcgacag caccgtgccg ccgaccgcgc tccacaccgc
    15001 gagcgttcgg gaacgccgcg ccgtttcgac cgcgtcggcc agcctttcca gccggtcgtc
    15061 caggatcacc gcgtcggcca cctgcgtggc cgccgtggcg ccataggaac ccatcgcgac
    15121 gcccacatcc gcggtcgcga gcgcgggtgc gtcgttgaca ccgtctccga cgaacgcggt
    15181 aaccccggcg cggcaagcat tctcggccga agtcaccttc tccgccgggc ccacctcggc
    15241 ggtcaccgcg tcgaggccga gcgtcgcggc cacttctcgc gcgttgtcca cgcgatcgcc
    15301 ggtcaccagc cggatttccc ggattcccgc ctcccgcaag cgtttcatgg tccgaggcgc
    15361 gtcgcggcgc acccggtcgc gcaccaggaa cgcggccgtg agcgcaccgt ccacgtccac
    15421 ccacaccacg ctcgccaggt ccagcttgcc ccggttcagc acgccccgcg cccaccccgg
    15481 caggtcgcgc tcccccggca gacggccgac cgtcacccgc cgcccgtcga ccacaccccg
    15541 cacgccggtg cccggggtct cggtcacgtc ctgcgctcgt tccacgggca cgcccgcggc
    15601 agccgccgcg cggacgatcg ccgcggcgag cacgtgcggg gaaaggcgct ccacgctggc
    15661 ggccaaggcg agcactcttt cctcagtcat tcccggcgcg cacacgacgt cggtgacctc
    15721 cggcctgccc tcgctcaccg tcccggtctt gtccagcagc agcacccgga cgttgccgag
    15781 cgtctcgagc gcggcgccgt ccttcaccac gaccccggcc cgcgacatcc gcgacatccc
    15841 cgcggtcacc gcgatcggca ccgccagcaa cagcgggcac ggcgtcgccg tcaccagcac
    15901 cgcgaccgcg cgaaccgcgt ccccggtgaa cagccacgcc gcggcggcca tcagcaaggc
    15961 caccggcagg aaccagatcg cgatccggtc ggcgatcctg gcgaccggag cggtgcccgc
    16021 gacggcgcgt tcggccaggc gcacgatccc ggcgtaggtg ctttcccccg ccgcggccgt
    16081 ggcgaccagg tcgacggcgg cacccgcgtt cacggttcca ctgtggacag tcgccccggc
    16141 gcgcttgggc accgggagcg gttccccggt cagcgcggac tcgtcgaagg cgccgtccgc
    16201 gtcgaggacg ccgtcgaccg acaccacctc acccggcagc acgacgatcg cctgcccggc
    16261 gacgacctcg tccacgccga tggtctcgag gccgtccgcg gtgcgccggt gcgttcggga
    16321 cggcgctctg tcgagcagca tcgaaaggtc gcggcccgca cgtcgcctcg cgccggcttc
    16381 gagcacatgg cccgtggcca ccatgagggc cacgatcccg cccgcgaggt actcaccgac
    16441 cgggagtgtc gccgcgagcg cgaggaccgc caaaaggtcg gcgccccacc gcctggcacg
    16501 gagatcggcc atgacccaca cgaccgacgg ccccagcgcg accaccgtcg ccgccgccca
    16561 caacactttc gcgccaccgc cgcccaccag cgacagcaca ccgcccgttc cgacgagcag
    16621 tgttaccgcg accaggagaa ccgcttcccg tgagcgcgcg agccgcaccg ccctcatcac
    16681 gccacgtcgt tccagacgta gtcgagccgg ttttcgaccg cgacgacccc gggaacgtcc
    16741 tcgaccatcc gcgtgagcgt ctcgacctcg ctgcgcttct ccacgcgccc gcacatcgtg
    16801 acgacgccgt cgtgcaccgc gacccgcgcg cgatcgggtc ccagtcccag cgcgcggagc
    16861 aacaccccgc gctccacctc gtgaaggagt tcgtcatcgg tgcgcacgaa cacgcgcacc
    16921 aggtcgctgc gcgagaccac accgaccagc gctccgcgcc gcagcacgaa aaggcgccgc
    16981 accccggtgc gcgcgaactc cgccgacgcg gcggtcagcg aggcgcccgc gtcgatggtc
    17041 agcgcgggcg cggtcatcag atccgaggcg accctgccgc tcattctgcg gtcgcgccgc
    17101 gaaagacgct tcgcgagcca cgatggccgt tcgtgctcgc gcaggtgcga caggagatcc
    17161 gcctccgaga ccacccccac gagcgcgccg tgccgatcga ggacacccac ggcgctgatc
    17221 gcccgcgcgg tcagcacctc ggcgatctcc ttgagcggtg tgtcggtgcg gaccgtcacc
    17281 gggtccgggg tcatgacggt ggaaacggtg agagacgtca tcgcggtcct ccactcgaac
    17341 acgccgcctc acgtccgacg gctcctcccc cgaaggtagg gaccgagcgg gggccgtcgc
    17401 ggcggtcctt cgcccaccag cggaaggacc taggtcgtca gttcacccgc aggaccgccg
    17461 ccccgttgac ccggtccgcg gcgagatcgg acagcgcgcg gtccgcttcc gccagcggat
    17521 acggcgatgt cgacacccgc aaccggtgcg accccgcgac gccgaggaac tcttcagcgt
    17581 cagcccgcgt gttggcggtg acgctgcgga cctggcgctc ctggaacagg tggcgctggt
    17641 accgcaacgg cgggatgtcc gagaggtgga tgcccgcgat cgccagcgtg ccgccgcggt
    17701 cgagcgcggc cagggcgggc aggaccaggt caccaaccgg ggcgaacagg atcgcggaat
    17761 ccagcggttc cggcggcgag tccccggcgc cggtcgcgga ggcggcgccg agttcgagcg
    17821 ccagcctcct ggcggccgcg ctccgcgtca tcacgtggac cgtgacgccc cgagcgatcg
    17881 ccacctgcgc cgtcaagtgc gcgctgccgc cgaacccgta gatccccagc actccgcgct
    17941 ccgggacctc cgcccggagc agcgcgcggt aaccgatgat cccggcgcac agcagcggag
    18001 cgagttcgtc gtcggtgtac ccgtccggca ggcggagcgc gtagcccgcc gggacgacgg
    18061 cgaactcggc atacccgccg tcggcgtccc accccgtgta aaccgagtcg gggcagaggt
    18121 tctcccgccc gcgcgcgcag taccggcacc gcccgcaggt accgcgcagc caggcgatac
    18181 cggcccggtc gccgatcgcg aacccggtgg cgggcccgtc gccgatcgcg accacctctc
    18241 cgacgacttc gtgcccggga gtgacgcccc gccggtgcac ggcaagatcg ccttccgcga
    18301 cgtgcaggtc cgtccggcag acaccgcaca ccagcacccg caccagcagc tcgccgggcc
    18361 ctggcacggg aaccggcgcg gtcacctggt caagcgggcg cgacaccatc ggccccggcc
    18421 gcgtcacccg ccaggcactc atccgctcgt tcacaccgtc gagaatgccc gcgacggcac
    18481 tcttccgcga ctgccgaagg tcctctccac tcgatgaatc caccatggtc accgggtgac
    18541 gggacgtagg cccctgtccg cgcccgccga ccgtggagaa ggtgggcgag tgtcccgcac
    18601 cgccgcccca ggcccgccgc cctccgcgcc tccacccgcc accgaaccgc cgaagcgcgg
    18661 ctggccgtgg tggctgactt cgctgctcgt cctggtgtac ctcgcgatcc tgttcggccc
    18721 tgccctgctc gaacggggca cgagcgccgt gccctacacc gagttcctgt ccaaagtaga
    18781 ccaggggcag gtcgactcgg tgaccgtcga cgaccacggc tcgctcagcg gggagctccg
    18841 tggcggcgcc ggcttcacga gccaggtgcc gaccgcgctc aacgacgcgt cgctcgaacc
    18901 gctgctgcgc tcgaagaacg tcaagatcac cgcgaagacc acgaccacct catgggtcag
    18961 cacgctcacc gcgttcctgc cgttcgcgct cttcctcggc ttgatgatct ggatcggtcg
    19021 tcgggtccgc cgctctctcg ccgacggcgg cggcgtcggc ggtcttggcg gtatcggcgg
    19081 tatcggccgg tcgaaagcga agatcatcga ggcgcagcgg cccaccaccc gattcgccga
    19141 cgtcgccggc tacgaagggg tgaagcagga agtcagcgag gtcgtggact tcctccgcga
    19201 cccgaccagg tacgcggcag cgggcgcgaa aggaccgcgc ggcgtgatca tgatcggacc
    19261 gcccggcacc gggaagacgc tcatcgccag agccgtcgcg ggcgaggcga gcgtgccctt
    19321 cctgtccatc accggatccg cgttcgtcga aatgttcgtc ggggtcggcg cgtcgcgggt
    19381 ccgcgacctg ttcgacgaag cgcgcaaccg ggcgccgtcg atcatcttca tcgacgagat
    19441 cgacgccgtc ggcagcaggc gcggccccgg tggcttcggc gggcacgagg agcgcgagca
    19501 gacgctcaac caacttctat ccgaaatgga cggattcgac cagagcagcg ggatcgtggt
    19561 gctggcggcc accaaccgcc cggaaacgct cgaccccgca ctgctgcggc cgggccggtt
    19621 cgaccggcag gtcaccgtgc cactgccgaa ccaggccgaa cgcgccgcca tcctcaccgt
    19681 gcacatcgac gggaagcacc tcgcccccga cgtcgacctc accgtggtcg ccaggggcac
    19741 cccggggttc tccggcgccg atctcgcgaa cctcgtcaac gaagccgcca tcaacgccgt
    19801 gcgcgacgac cggaccgtgc tcacggccgc ggatttcgcg accgcgcggg accgcgtgct
    19861 gctcggcagg cgcgatgcgt ccaacgcgct cctgcccgag gaacgggaat ccgtggccgt
    19921 ccacgaatcg gggcacgccc tcgtagccgc gctgtgcgag cacgcggacc ccgtcaccaa
    19981 ggtcaccatc ctgcccgccg ggatggccct cggtgcgacc gaacagctcc cggaagccga
    20041 acggcgcctg taccgggagg actacctgag cgatctgctc gcggtgcgca tgggcggcag
    20101 ggcggccgag ctcgtggtct tcgggcaagg ctcgacgggt gccgcgaacg acctcgccga
    20161 agcgaccgcg ctggcggtga agatggtgac cgagttcggc ctctcccccg cactcggccc
    20221 gatcggctat ggcaccggag cgcacgccgc gccggtggac ccggtggagg ccgcgcagag
    20281 gccgtactcg gaacacacgc agcggacgat cgaccaggaa gtggccaggc tcctcgcgga
    20341 agcggaagcg cgcgccgtcg ccatgctcac ctcccggcgc gacgcactcg accggctcgc
    20401 ggcccagctg cgggagcagg aaaccgtcga cggcgacgcc gtgctggcgg cgttgcgcga
    20461 aaccaccgcg gcgcccgcgc gctgactggc cagtgtcacc ggcggcgagg acttcttcct
    20521 ctgccggcgg ggcacggacg agatcgacac tcggcccgtg gcgcggattc gcgcgaacgg
    20581 caatgaaagg ggtgcgccat gccgaactgg tggtaccacg catgcggtgg cacgggctgg
    20641 ttcgggccgg ccatcggcct tggcatcgtc ctgatcgccg ggatcgtcct gctcgcgatc
    20701 gcgctggtgc gccgcggttc gaaaccgcag gcaccggacc cgacggccat gcacgttctc
    20761 gaagaacggt tcgcccgcgg ggaaatcgac accgaggaat tcgaacaacg gcgcgacatc
    20821 ctgcgccggg cagcggaaaa cgggacgagg agaacacgat gacgatcgac cccgcgcgct
    20881 ccggcggcac gccgagcctg atcgaccagg ccatgccacg gcccgacttc acccttaccg
    20941 agcacctctt cgtcgacgca ccggcgggtg ccgtctacga cgagatcggg cggttcgacc
    21001 tcggccgggt ttccgatccc gtgctccgcg tcctgttctg gtgccgggcg tttcccgaac
    21061 ggctccagcg cctgctcttc ccgaagggcg cggaagagat gacctcggcg gagatcgcc
//
