LOCUS       NZ_CP059997            41056 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Amycolatopsis sp. CA-230715 chromosome, complete genome.
ACCESSION   NZ_CP059997
VERSION     NZ_CP059997.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. CA-230715
  ORGANISM  Amycolatopsis sp. CA-230715
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10363158)
  AUTHORS   Jorgensen,T.S., Gren,T., Oves-Costales,D., Ortiz-Lopez,F.J.,
            Carretero-Molina,D., Gonzalez,I., Blin,K., Genilloud,O. and Weber,T.
  TITLE     Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a
            35-Module Type I Polyketide Synthase
  JOURNAL   Microbiol Resour Announc 10 (38), e0080521 (2021)
   PUBMED   34553997
REFERENCE   2  (bases 1 to 10363158)
  AUTHORS   Joergensen,T.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2020) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-JUN-2019
            Assembly Method :: Flye v. 2.4.1-geb89c9e; Unicycler v. 0.4.8-beta;
            SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology :: Illumina MiSeq; PacBio RSII; Oxford
            Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,592
            CDSs (total)                      :: 9,498
            Genes (coding)                    :: 9,434
            CDSs (with protein)               :: 9,434
            Genes (RNA)                       :: 94
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 10 of 64
            Pseudo Genes (incomplete)         :: 60 of 64
            Pseudo Genes (internal stop)      :: 2 of 64
            Pseudo Genes (multiple problems)  :: 8 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 41097
            Orig. end                         :: 82153
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP059997.1.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            Bacteria and source DNA available from Fundacion MEDINA, Grenada,
            Spain.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="PKS-like"
                     /region_number="1"
                     /rules="(t2pks2 or ksIII)"
                     /tool="antismash"
     cand_cluster    1..41056
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /kind="single"
                     /product="PKS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41056
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21056](+)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21056
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     gene            complement(126..3419)
                     /locus_tag="HUW46_RS00225"
                     /old_locus_tag="HUW46_00046"
     CDS             complement(126..3419)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012602.4"
                     /locus_tag="HUW46_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00046"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_215545315.1"
                     /transl_table=11
                     /translation="MGVQRVPGYCTLCKSHCGSVSVVDRDRLLAVEPLDGHPSGGALCA
                     KGRAMPELVASPKRLLHPLKRTNPKDAADPGWVRVGWDEALDEIAGRLAEIREESGPES
                     VAFAVTTPSGTPMVDGSEWVNRFVQSFGSPNTVYATEICGWHKNFAHAFTFGKGIGTPD
                     YRAAELIVLWGHNPARTWLAQASAIAEARRDGAKVVVVDPKRGGSGQQADQWLRIRPGA
                     DAALALGAVNHLIGGEHYDAEFVRSWTNGPFLVDSETGDVVRENGGFLVWDNASGAPRR
                     YDTSRALSAPHDVALHGRFRLADGRAVRPAFDLLAEHVAEWTPAKVAETTWIELAEVTA
                     FYAMLAKYRRVAYYSWTGVGQHTNATQTERAMSVLYALLGSYDRAGGIRWLDKHRPNPL
                     ADFAALPAEVREKALGKQEMPLGPPAQGHVTARDFRRAVLDGEPYRVRAMIGFGANMVV
                     SQGSADENRRALRALEFQVQCDLFENPTAATADFLLPVCAPPERDGLMIGFDNSADGEE
                     LVQLRPRMIPPAGESRSDYDIVTGLAARLGMSGDFFGGDVDAGRNHQLAPLGLTVDELR
                     ANPGGIRVPIDQRERKYATELADGTVTGFGTESRRVELYSGLLRRHGQPALPTFVEPDG
                     IAPGDAAFPYVLTTAKNGHYTHSSLRSLASLRRRSPDPGVDISPALAARRGLAEGDWAI
                     VRTPDGEARLRVRLDDSLDDRVVIAEHGWWDDQAPLATPGLAALGRRTSNINAALSDRR
                     RDPISGSVPLRAVACDLVRDAETSAGNWAGWRAFVVTGRTPVENGALSLTLRPADGGEL
                     PEFRPGQNVTVRAPRLGTQRAYSLTNGTGDLRIAVKNIGGRMSAHLHTAGEDVLELKAP
                     TGTFTPPVGGNRTVLCIGGGIGITPFLGYLETLAEGRPVPPRVRVVYTHRGEEGETPIA
                     DRLAELAAGLPGVELVRHVTGEGTGRFTVDERLDEFLATGPVVYLCGPAAMMAELTEQL
                     AARGVDRFDIFGEEFFTEVEVPETLSPATVRFTRSGREIVWTPESGTLLDAAESAGIRL
                     GSGCRTGVCESCRVEVRRGEITHLSTVDTVAGSCLTCQAIPLSDVDIEA"
     gene            complement(3513..5267)
                     /locus_tag="HUW46_RS00230"
                     /old_locus_tag="HUW46_00047"
     CDS             complement(3513..5267)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683090.1"
                     /locus_tag="HUW46_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00047"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_215545316.1"
                     /transl_table=11
                     /translation="MRGYRPILKHLSSLTAAVVVTAGLAVAGAGQAHAATALPSHVFAP
                     YFEAWTGQSPAALSQQSGAKHLTMAFLQAATKGSCTAYWNGDAGMPIGQGTFGADIDTI
                     QARGGDVIPSFGGYTADNTGTEIADSCTNVDSIASVFENVITTYDIPRIDLDIEDNSLT
                     NTAGIDRRNKAIKKVQDWAASTGRSVQFSYTLPTTTHGPADSGLAVLQNAVSNNARVDV
                     VNLMTFDYYDNAAHNMAEDTKTAATGLVSQLAALYPGKTQAQLWAMVGVTEMIGIDDFG
                     PAETFTTADGPVVYDWAVSKGINTLSFWALQRDNGGCPGTKGSDSCSGIQQDTWQFSKT
                     FAPFTGGGSQPADDFSVAVNPASGAVDPGGSVTPTVATALTNGAAQQVTLSVSGAPEGV
                     SASVSPATVTAGAKATLSVSTTAAAPPGTYPITVTGTGSSGGKSVTRTATYTLTVNGAN
                     PGGSVVNGGLETGALSPWSGEASVVASPAHSGAHALQLAATGSQTGEVRQNVALQPNHA
                     YTLKAWVQGNYAYLGVSGGASASTWTSSTGWTQLSVPFTTGASGAVTVFAHGWYGQGAV
                     YADDFSIT"
     misc_feature    5328..5343
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.38"
                     /tool="antismash"
     gene            5514..7604
                     /locus_tag="HUW46_RS00235"
                     /old_locus_tag="HUW46_00048"
     CDS             5514..7604
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016289.4"
                     /locus_tag="HUW46_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00048"
                     /product="M28 family peptidase"
                     /protein_id="WP_215545317.1"
                     /transl_table=11
                     /translation="MRAKGIGAVLAAVALSVSFGVAPADAAPETILGFTPKHSAAQRAA
                     EQTFSGVLSPAVARELDRDLAHETGLVSTPGDYKRMRKVVDYLRSYGLQPQVHTYYVYQ
                     SVPRRIEVTMTSPRRITLPTKEPCLAVETDCANMVVGYNALSPSGDVTAPVVYANYATP
                     ADFAELDKRGISVEGKVVLARYGANFRGVKSKLAAAHGAKAVIIYSDPKDDGNTNGAVY
                     PGGPWRNPDGIQRGSVQQLMQYGGDPLTPGWASTKDAPRIDPKDSNIAPIPTTPISYAA
                     AEPLLKALGGPQVPANFQGGLPFPYHFGPGPTTVRVNLDIAYETKPLWDVTATVPGRSQ
                     PDQTVYVGAHRDSWTYGSDDNLSGTEAVLQIGRGIGALLKTGWRPERSITLATWDGEEY
                     GLFGSTEYAEQMGDRLKGAVTYLNMDGAGGKHFGAAGTPSLDRTIRQVTKDVPWPGTKG
                     SAYDAWVADHGGKVPPISRLGSGSDYTAFFDRFGVPSANIGSSTDSGNYHCSCDNFWME
                     DHYIDPTWQYHVATAQTVGLTTLRLANADVLPMYYSDYAAETGDYLTAFGKQQSTVDVS
                     GLKERAAQWQRAAKAAEDRVANRLATGGDGPIEGIRNSIASRLFSATERQLLTDAGLPG
                     RPWYRHQVYAPGINAGYGTQVLPGLHDAVLERHNPAEAATAADSFDASLRKATAVVSAA
                     GW"
     misc_feature    7703..7717
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.4"
                     /tool="antismash"
     misc_feature    7996..8010
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
     misc_feature    complement(8005..8019)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    8138..8151
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.3"
                     /tool="antismash"
     misc_feature    8138..8152
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.38"
                     /tool="antismash"
     misc_feature    complement(8140..8153)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.97"
                     /tool="antismash"
     gene            8350..10347
                     /locus_tag="HUW46_RS00240"
                     /old_locus_tag="HUW46_00049"
     CDS             8350..10347
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00049"
                     /product="hypothetical protein"
                     /protein_id="WP_215545318.1"
                     /transl_table=11
                     /translation="MPIDAHHLSGLRAITGGLVEELLSRPGGENRALPVVVAIGARGTG
                     KTALLTELAARCESVPHAHLDFERHDWENVQPRELLGHLAFDLGRHWRQFGRLAFPRLW
                     LCMLVLGAPVEITDRRAALRKLRELLAQNQPLEHNREAIVDVVKLAGGVASGRSLPGWN
                     EATDLLLRGLSWYDRRRLVGKIKAIPSGAGNHEDFLIEIAKHAQGDEEDRAGVDATFCD
                     AFLADLRRDYSGINRARRTLNSMVLLDNAHTPGGRAFLRALDEARRRCPDEADPLAVIA
                     TSRTWNPDWNESWTLLTPHHTGDREPARPTSHRTNGLHRPTPRQPSDVEDDWAAGSPES
                     RWHPWYLLELGTLSKEDTMDVAAGHDIHPASRLPRFLHRLTDGHPGAITEVVAQVAHRY
                     DSANPALLRSALRTAVPGQEGGESTLLAEIRDHLLQDFPEASQQDLITASAAIDVEMLF
                     HKEILDLRNPVGEGALFKSLGEYLWLRAEPGESPQYVLHPWLRRILLQELASRADDHPL
                     SWVEVHTRCRDFYEKNGRIVAARYHDLALEDVGQTIVHLRRPFDSKHAEFDVPAAESWL
                     AELDVITAAPNRLDKDADPYDQVQRLVGEFDDELETTLAWLVVALWISRDPLGDPGRTL
                     DSTIESSFHHLAQGRGRGSMLLHERAERYR"
     gene            10344..11840
                     /locus_tag="HUW46_RS00245"
                     /old_locus_tag="HUW46_00050"
     CDS             10344..11840
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00050"
                     /product="hypothetical protein"
                     /protein_id="WP_215545319.1"
                     /transl_table=11
                     /translation="MIGRKGKTEGGTILPPRPTWSKWLWLSGGVLLVVVAVAAIIVVPP
                     WISEAGLTCDGAVRQRGEHSECTGPTDGSFVFSPDLATVEQRIHTENDAVAASGKPYVT
                     IAVFIPMTLTEHDILSPEWVRHQLEGAYIAQRRANTTQSWGSLPLVRLLLANPGSQLKQ
                     WEPVVDDLLGRVQSEHLVGVTGIGLSLDTARDAIRKLSDHKVPVVASHLAAEQFSEIPG
                     FLRVSPTSATYGMATANFVKPTAKTATIVQDQNAGDLYPKTLADGFTAKFVDDAHRIVG
                     RTEAYDSSLPGIENTFLQMMPNICGNAPDVVYFAGREDHLVSFVAQLAQRPCLDRHITV
                     LTGDLALVGPPGQEMRRGLQANVTVIAPGLAHPQAWTAEPKAFNPAAVASFHETSCVDC
                     FEAVFPKERLDDGIAILAHDAVLTVVWAIRGIPRVSPAQVTAEDVLQAKNRLHDRFAVP
                     GASGMISFDDRGDPVNKAVPILRVRLDNTPEFLQLSTPGG"
     gene            complement(11846..12412)
                     /locus_tag="HUW46_RS00250"
                     /old_locus_tag="HUW46_00051"
     CDS             complement(11846..12412)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101818.1"
                     /locus_tag="HUW46_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00051"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215545320.1"
                     /transl_table=11
                     /translation="MDPTKRPRRADSRRNYERLLSVADAAFAERGTSAPLEGIARESGV
                     AIGTLYGHFPTRLALIDALLHERNEALFAEGERLRAQEPPGEALEAWIRAAVDHAAIYQ
                     GLAALLVAGIDDRASDLHDACRRMESIGGRIAAGASEAGAVRRGVTAADVSTVISAVAW
                     VREQVSPAQADRLLATALAGLRQAS"
     gene            12502..13365
                     /locus_tag="HUW46_RS00255"
                     /old_locus_tag="HUW46_00052"
     CDS             12502..13365
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101817.1"
                     /locus_tag="HUW46_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00052"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_215545321.1"
                     /transl_table=11
                     /translation="MILVTGATGAIGKHLVRELDQAGTPFAAFVRDEAKGQALGCEFIV
                     GDFGDPASVAAAMRGVDVLLLNGNGALPVEGEQPMIAQQKAVIDAARDAGVSHIVKISA
                     QGAREGGKLSTGAHWEIERHLKSSGVGWSILRPNSFMQNFITGAATLIESGTVQGPFPH
                     SRVPYVDCYDIAACAAALLTAAGPTSRTFALTGPESLTQREIADRFGIALGTPVTSVEL
                     SPEDMVAGLRSQGLPEWFARDAVALWADVAADRTLATTTGTVEELTGRAPRTFDEFLTA
                     NLAAFR"
     gene            complement(13369..13644)
                     /locus_tag="HUW46_RS00260"
                     /old_locus_tag="HUW46_00053"
     CDS             complement(13369..13644)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00053"
                     /product="hypothetical protein"
                     /protein_id="WP_215545322.1"
                     /transl_table=11
                     /translation="MERTTEWLSDEDVLERTGFLHLMFANERHSLGEALDNLLAGLDDL
                     VTITERHTYEHDRGRSASVAHARRFRDTTLHQLTAAYEHHPDCPWR"
     gene            13819..14682
                     /locus_tag="HUW46_RS00265"
                     /old_locus_tag="HUW46_00054"
     CDS             13819..14682
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="HUW46_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00054"
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_215545323.1"
                     /transl_table=11
                     /translation="MGSTNASTPRARALADMLNAVLEKSRHSQRSIAKLMGYSHVTVGR
                     WTRGEATPDDVTVATFLAHLGIVGEERDRILEVASAPDGGDWLTVGPGGIPSQLAGVMN
                     LERNAVRLTNWSPLFVPGMLQTQAYARAIIERSPRITDSEIDHLVTVRLGRQHAISRDE
                     APLKITSFLGVPALRGGIGGTSVMCGQLRYLLKASRFENVDLRVVPVDGEWHNGIMGPF
                     SLYDSSGGEPTVLHIEHHRTGAFISDPSDVHAYQEDLVKDLRRLAYGPDETRELIQEEL
                     KNREDA"
     gene            14679..14858
                     /locus_tag="HUW46_RS00270"
                     /old_locus_tag="HUW46_00055"
     CDS             14679..14858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223959.1"
                     /locus_tag="HUW46_RS00270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00055"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_215545324.1"
                     /transl_table=11
                     /translation="MKNKVPPPRWRTSSYSGQQGDCVEVKLDTAIGVRDTKDRTGGDLD
                     LHPSAWNALLTRLR"
     gene            15116..16129
                     /locus_tag="HUW46_RS00275"
                     /old_locus_tag="HUW46_00056"
     CDS             15116..16129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079898.1"
                     /locus_tag="HUW46_RS00275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00056"
                     /product="S1 family peptidase"
                     /protein_id="WP_215545325.1"
                     /transl_table=11
                     /translation="MPSRKSLALFAAFSAAAMTTGVCAQTASADPLAFAQLQQNSIDQA
                     TQVTNTLGASSGGFYLDQGKAVVNVLDDTAAQTVRDAGLTAKKVAHSFAALTAAKDSLD
                     QVHDVPQTAWGIDTRANQVVVTIYSAATPATAAKVTAAANRLGDRARIEHETGKLELYI
                     ADGDAIRNSSGRCSLGFNVKKGSTPYLLTAGHCTNLGGTWSGGDVTGARIVHSDCPGAD
                     SGLLTRPNGTGPGRINTGQVISRAGTPTVGERIQKQGSTTGGGSGTVKSVDQSVNFDVG
                     VLNHEFGTSAHTDHGDSGGPAYDGSTGLGTLSGGNSTTSYFYPLTRELSSYGVTLA"
     gene            complement(16187..16462)
                     /locus_tag="HUW46_RS00280"
                     /old_locus_tag="HUW46_00057"
     CDS             complement(16187..16462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227717.1"
                     /locus_tag="HUW46_RS00280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00057"
                     /product="hypothetical protein"
                     /protein_id="WP_215545326.1"
                     /transl_table=11
                     /translation="MSETEDPKPASTEPPAFTPSVPETDYTDGGVPTFDFVKDRIEKRA
                     ATAEGSTELAGLGTGQDMAALDKKIADRDEAAKDKLAEIRKAMRGE"
     gene            complement(16528..17733)
                     /locus_tag="HUW46_RS00285"
                     /old_locus_tag="HUW46_00058"
     CDS             complement(16528..17733)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331814.1"
                     /locus_tag="HUW46_RS00285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00058"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_215545327.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-08, bitscore:
                     34.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.5e-05, bitscore:
                     23.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTENPVRTEAEWLETARDVAAKLAVDAVERDRANQTPHREVQL
                     LKDSGLVTLLGPPEHGGGGQSWETAYRVTREVARADGSIGQLLGYHYLWAWAARLVATD
                     AQIAAVEELYTSNKLFFGGAVNPRDSDLTITDEGDEIVYNGHKSFSTGSKVSDLTVLEG
                     VLSGTEDHIFAIVPSKQDGIVFHDDWDNIGQRLTESGGVSITGVRVPWESAAGYVDKAF
                     RPLTYNTLNVPAIQLVFTNFYLGIAQGALETALAYTRDRTRPWPYGGDDKESAAQEWYI
                     LDAYGDLQAKLWAVEALTDKAGAAISAVLHAPREDLTPAARGEIAVLIAAAKQRAIDTG
                     LEIGTKIFELTGARASASQYGFDRFWRNLRTHSLHDPVAYKRREVGAYALLNEIPEPTW
                     YT"
     gene            complement(17958..18266)
                     /locus_tag="HUW46_RS00290"
                     /old_locus_tag="HUW46_00059"
     CDS             complement(17958..18266)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00059"
                     /product="hypothetical protein"
                     /protein_id="WP_215545328.1"
                     /transl_table=11
                     /translation="MTGYVRPVLTDGGIRRDGRKAIGSVSARHSAAAARRLVRDSAVLV
                     SLLWAAEDRVFPIEHARRYADALGAQPRTVADSYTYLAEDQPERTAEALRGLLTEPS"
     misc_feature    18263..18283
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.82"
                     /tool="antismash"
     misc_feature    complement(18662..18676)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    19440..19454
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.62"
                     /tool="antismash"
     misc_feature    complement(19453..19468)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.43"
                     /tool="antismash"
     gene            19672..20004
                     /locus_tag="HUW46_RS00295"
                     /old_locus_tag="HUW46_00061"
     CDS             19672..20004
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00061"
                     /product="hypothetical protein"
                     /protein_id="WP_215545329.1"
                     /transl_table=11
                     /translation="MKDTTPPAFAAPFVPAQPTARSLSRTHRTTAFSQRLLVHWDPETG
                     WAHLAVAEPGGANPRFAGFHRFPSGDTDSVLAALTEAGWDAGQPTELEDGMLGVRARPG
                     REREGR"
     gene            20001..21056
                     /locus_tag="HUW46_RS00300"
                     /old_locus_tag="HUW46_00062"
     CDS             20001..21056
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.4"
                     /locus_tag="HUW46_RS00300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00062"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_215545330.1"
                     /sec_met_domain="ksIII (E-value: 1.3e-74, bitscore: 250.2,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDDLHLTGIGCHLGSLTPVSGPVTAGTYTPEEAAKTGQLSTSV
                     ADRHGPDLAVSAAREALRHADAVSGETVRPSLSLHAGIYYAGIDFWHAASYVRDQLGIG
                     PWAGLALEIGAMSNSMVAGLDLAASVLSGRPDHEDVLLTAGDRFGDPGFPHWSTDIGIV
                     YGDAGSAIVVSRRPGFARLLSVASFSDPSLEGLQRGAEPFRSVSSAARTPIDIRLRKRQ
                     WLEDRGTDYVHTRNSDAVTTVVKTALTDAGLDLPDLAKICAPHYGRHLVRSQILRPLGI
                     AEEQTMTGLGLRLGHLGASDQIVALHHLMRTGEARRGDHVLLLGVGVGMTWTAAVLRIE
                     REIPPPGGIGR"
     gene            complement(21109..21390)
                     /locus_tag="HUW46_RS00305"
                     /old_locus_tag="HUW46_00063"
     CDS             complement(21109..21390)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="HUW46_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00063"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_215545331.1"
                     /transl_table=11
                     /translation="MGRRERPLDEDGGAVTRFAAELRRLRVDAGTPTFRELARRAHYAA
                     GTLSEATGGKKLPTLAVTTAFVRACGGDERAWEARWRAASAALAAERD"
     gene            21594..22112
                     /gene="msrA"
                     /locus_tag="HUW46_RS00310"
                     /old_locus_tag="HUW46_00064"
     CDS             21594..22112
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227722.1"
                     /locus_tag="HUW46_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00064"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_215545332.1"
                     /transl_table=11
                     /translation="MSTPSEKPVEKAILAGGCFWGMQDLFRRQPGVVSTRVGYTGGTVA
                     NATYRNHEGHAEAIEVLYDPAETDFRALLEFFFQVHDPSTKDRQGNDIGTSYRSAIFYT
                     TDEQKKVAEETIAEVDASGLWPGKVVTEVVPAGDFWEAEPEHQDYLLRIPHGYTCHFPR
                     PDWKLPARH"
     gene            22241..24277
                     /locus_tag="HUW46_RS00315"
                     /old_locus_tag="HUW46_00065"
     CDS             22241..24277
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417429.1"
                     /locus_tag="HUW46_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00065"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_215545333.1"
                     /transl_table=11
                     /translation="MAEGKSTARPRELGRGARNLVVAAIMLGMLLSALDQTIVATALPT
                     IVGDLGGGSHLSWVVTAYLLAETIMTALIGKFGDLFGRKKAFIASVALFLVGSFFAGWA
                     DQMGTLIAFRAVQGLGGGGLMVTAAAVIADVVPLRERGKYQGFIGAVFGISTVVGPLLG
                     GLFVDHLSWRWAFYVNIPLGILVLVIAAIALPRVVSTAKPRIDYLGIILIALAASGLTL
                     VTSWGGTEYPWGSPTILLMAAASVVLLIAFVLVEQRAAEPMLPMRLFRGRVFSVSGILS
                     FLVGFAMLGGITYLPTYLQYVRGETATQSGLWMLPLVAGLMAAALATGTVISRTGRYRL
                     FPIAGSVLMVAGLLLMSLLDADTSYWLMSLYMIVLGAGVGLIMQVPVIVVQSTADYADL
                     GVATSGVSFLRTLGSSFGVALFGTIYSGNLPDKLAAALARNPLPPGVDPRVAQSPQALH
                     ALPASLRTPIIGAYVDTLHLMFLYAAPVGVLALVVALFLKEVPLRDTSRAAASGNSGVG
                     ESFAVPASSDSEQELEKLIATMMGRLKSDPGNEILARTGLTITIAQAWLLQHVYRTSVD
                     DGDATMQEIAELTDVPAGIFEPTAQQLVGLGLLVETDGHYRFTTEGSEVFTQLVAGWRD
                     WLLDQLADWREPRQREFTEAVDAMARRITDTGRSLGVGRHAML"
     misc_feature    24360..24375
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.21"
                     /tool="antismash"
     gene            24398..26590
                     /locus_tag="HUW46_RS00320"
                     /old_locus_tag="HUW46_00066"
     CDS             24398..26590
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666807.1"
                     /locus_tag="HUW46_RS00320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00066"
                     /product="alpha-N-acetylglucosaminidase"
                     /protein_id="WP_215545334.1"
                     /transl_table=11
                     /translation="MRTRLLALTCAAVTALGTVTVTGAAAGTDAAGAFDTAAARASLHR
                     VLPGADRQFRLRALPPQETGDHFEISGHAGAITVAATSPATLLAGAGWYLEHVAGVDIS
                     LPGQSVSRLPGVLPAPPGVIRQAASVANRFALNDTDEGYSGPYRDFASYEREIDVLALH
                     GVNEVFVETGTDAVYYEALRSFGYTRSELLSWIPGPAHQPWWLLQNMSSFGGPVPERLV
                     LDRAALGKRLVDRLHDLGMTPVLPGYFGTVPPRFTEKNPSARVVPQGDWGGFTRPDWLD
                     PRNPVFARLAAEFYRWQARLVGTGSMVKMDLLHEGGQAGDVPVADAARAVFAAMDRARP
                     GATWVLLGWQSNPKPEIIDAVPDRKRLFIVDGLSDRYNDLDREKTWKGTPYAFGTIPNF
                     GGHTTIGANTGVWSSRFDQWRSKPDSALAGIAYLPEGTGTDPVAFEMFTDLAWHDGPLD
                     QAAWFAGYAARRYGCADPHATAAWDALRRGPYSMPSGKWSEAQDGLFTARPSLTATKAA
                     AYSPEEMRYDPATVKTALAELLAVAPSCRTTDAYRYDLVNTARQVLANASRDLLPRLKS
                     AYDRKDLPGFRALAGQWRGDLALLDSLLGSDPRFLIGPWLDAAKSSARGDAQRARFEYD
                     ARSIITTWGDRAASDDGNLHDYANRELSGLVRDFYAMRWNTYLDSLDKALVTGGQPAPI
                     DWYALEDGWNRARRSYPVTATGDPHQLATQVANLPS"
     misc_feature    25850..25852
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(26637..28118)
                     /locus_tag="HUW46_RS00325"
                     /old_locus_tag="HUW46_00067"
     CDS             complement(26637..28118)
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020498184.1"
                     /locus_tag="HUW46_RS00325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00067"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_215545335.1"
                     /transl_table=11
                     /translation="MDPIFAGTTTGRAALAGYLKTTLDAVGEGVRARGGPIPAGEPDAL
                     ARAWAAGFGALLPETGAGPDHALTEIVTRLAEGAADPADPACAAHLHCPPLAVAVAADT
                     AVSALNPSLDSWDQAPAASALEDRLVAALAGLTGYDAGTAGGAVTTGGTESNLMGLLLA
                     RDRIVRAITGAEVSRTGIPAELTGKLRILCSSVAHFSVARSAGLLGLGEDAVLPVAVDE
                     ADRMRPDALCVELMRVRERGEVPLAVVATAGTTDLGAIDPLGAIAELTYAHRVWFHVDA
                     AYGGGALFSDRLAPLLAGIGRSDSVGLDLHKLGWQPVAAGVFLSRDRAGFRTLDRTVAY
                     LNPADDEAAGYRSRLGLSLRTTRRADAAKIAVTLRAFGRRGLGALVDRCHDLARYAAAE
                     IGADPGLELRAEPTLSTVVFRFLPPAGTDPDQANARLRRALLASGTAVVGRTTMPDRSG
                     RPATYLKLTLLNPTTTQADIDKLLLDIRAEAELSR"
     misc_feature    28109..28123
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.19"
                     /tool="antismash"
     gene            complement(28266..29756)
                     /locus_tag="HUW46_RS00330"
                     /old_locus_tag="HUW46_00068"
     CDS             complement(28266..29756)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680709.1"
                     /locus_tag="HUW46_RS00330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00068"
                     /product="MFS transporter"
                     /protein_id="WP_215545336.1"
                     /transl_table=11
                     /translation="MRSPVHTSRAPRSLGAAWQALAGLSAVFLFEMLDNSILNVALPTI
                     GRELATSTTTLQWVTGVYSVVFGGLMLVLGALADRAGRRKVMLFGLVLLGAASFATVFV
                     TAAWQLIAVRALMGVAAAMTTPGSMALAFRLFDDDRLRTRAITLISTVGMVGLAVGPTA
                     GGLVLAVAPWQVLLLANAPVAALAFLGIRAGIPADDPADLHRDPVDVAGAVLGTATIVF
                     ALLAPTFFVEAGAASALPWAATAAAVAAGTGFVLREKAIRHPLLDLKLIARPLVSSGLA
                     LKAAAGLATAGLSYLATLHLQLGLGWAPAQAALGMLPQVVVLIAGGAVIGPLLDRVSPV
                     KAAWLSAGAVVCGLAVYTAFGRFGYAWIAVALALVAAGMRVVGVVAGTNVMRGLPANRT
                     TIGAALIDTASEVTTGVGIALSGTILAVVVPGALTTAAWSARQAAGFREAITYAGLALT
                     LASAALVGWGILRGPRSGDDAPEPSTSDTAGESASIRS"
     gene            complement(29870..30496)
                     /gene="bluB"
                     /locus_tag="HUW46_RS00335"
                     /old_locus_tag="HUW46_00069"
     CDS             complement(29870..30496)
                     /EC_number="1.13.11.79"
                     /GO_function="GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032363 - FMN catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bluB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019812293.1"
                     /locus_tag="HUW46_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00069"
                     /product="5,6-dimethylbenzimidazole synthase"
                     /protein_id="WP_215545337.1"
                     /sec_met_domain="PF00881 (E-value: 7.4e-29, bitscore:
                     100.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAEFLYEVVGKRRDVRSEFTGEPVDPEVLRRVLTAAHQAPSVG
                     LSQPWDFVLVEDGGTRRAFHGHVQAERARFAGSLSGAAAKVFDGIKIEGVLDAPLSIVV
                     TYDPARGAPAVLGRHAIADAGLYSVCLAIQNLWLTATAEGLGVGWVSFYREEFVRELLG
                     IPAHVRPVAWLCVGPVERLAEVPDLERAGWRSRMALDEVLHTERW"
     gene            complement(30493..30969)
                     /locus_tag="HUW46_RS00340"
                     /old_locus_tag="HUW46_00070"
     CDS             complement(30493..30969)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950827.1"
                     /locus_tag="HUW46_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00070"
                     /product="DoxX family membrane protein"
                     /protein_id="WP_215545338.1"
                     /transl_table=11
                     /translation="MAPLVILVVVTLVLLGAGAAGVRALRPWPVAVRGGLAAMFVATGV
                     AHFVGMREELISMVPAALPAPGFLVTLTGLLELAGAAGLLWRRTAPWAAGCLGALLVVM
                     FPANVVKALDGRAIPFEDQLVPRTAMQVVFVAATLAVVVHHLRVRAGRTGQSPA"
     gene            31063..31608
                     /locus_tag="HUW46_RS00345"
                     /old_locus_tag="HUW46_00071"
     CDS             31063..31608
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005453912.1"
                     /locus_tag="HUW46_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00071"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_215545339.1"
                     /transl_table=11
                     /translation="MPYHHGDLRRAVLDAAVAAITEHGAAGISLRDLARRAGVSHAAPV
                     HHFGDKAGLLTALAAEGYEMLAAALAETRERTGDFVEAGVTYVRFALGHHAHFAVMFSP
                     GLFRADDPAVVSAQERTYELLVSGARAVRGEPGVAEIAAWSLVHGFATLWLTGALPPGA
                     AEDPERSARAIARILTGS"
     gene            complement(31620..32585)
                     /locus_tag="HUW46_RS00350"
                     /old_locus_tag="HUW46_00072"
     CDS             complement(31620..32585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00072"
                     /product="hypothetical protein"
                     /protein_id="WP_215545340.1"
                     /transl_table=11
                     /translation="MIIGTRDRGAGRQSPARERRFDPNGVSVTKAYLALAAACGLCGLV
                     ASPAAQAAPEWQQVGSGITGGVSGMAVTGSTAAGTDAVIVRDNKEDGQNRVALVRVPAS
                     GAATSTDLAWSGELPTDLEAIDAVPGKAGEFVALASSGTAYLITVDSAKATVVRSFPLP
                     DLDDKANYEGFALSAIGGKTVAVWADRGKDAEPGVVSAAEVDLGQGKFSAPVSAKFTAP
                     YPEKKVRHVSDVKVLADGALVISSASDNGDDGPFDSALYRGGTVKLDGDRVALDTVKDP
                     TPVAKYEGHKIEALACGAASGVLGTDDENLGGFVRLANFC"
     gene            complement(32629..33762)
                     /locus_tag="HUW46_RS00355"
                     /old_locus_tag="HUW46_00073"
     CDS             complement(32629..33762)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033740.1"
                     /locus_tag="HUW46_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00073"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_215545341.1"
                     /transl_table=11
                     /translation="MTTAAVIGGGIAGTATAIALLKAGIGSTVYEAYPTGADDAGAFLT
                     LMHNGMDALAAIDAHEVVAAKSFATNEVEFSYDGGALPVQPIGSAREDLLAPRTIRRAD
                     LHRVLHDEFVRRGGTIAHGKRLASFDGGVCFTDGTRAEADFVVGADGIHSAARRLIDPD
                     APEPRYAGLAVVYGYAPAAPHPAPPATYRMIQGATAFFGYTTDPGGTTWWFARLPGAEL
                     TGTRETTPARWRERAAARFDGDRNPAAEIIRATGEDVFGGNAYDVPTTPRWSSGAAVLV
                     GDAAHAASPAAGQGASMALEDSVVLAMCLRDEPARVDAFRRYEEIRRARVERLVAVSGS
                     QGAGRTTSEEARRRETERAWLYGHHLEWSSPITASPR"
     gene            complement(33830..34702)
                     /locus_tag="HUW46_RS00360"
                     /old_locus_tag="HUW46_00074"
     CDS             complement(33830..34702)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF020123.4"
                     /locus_tag="HUW46_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00074"
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="WP_215545342.1"
                     /transl_table=11
                     /translation="MKYRELADADCAIAQALGVVGDWWTLLVVRDIAGGLTRFDALQQE
                     LDISRKTLTERLKALVADGVVEKVHYSERPPRYEYRLTDTGRGLLPVLVALQDWGTRFV
                     AGDGSLTATSSPTSAEARRVRALVGTRVPATLLISDTGEPMTPTGQGWSVLYAFPGAFA
                     PRGNPLPPGWGDIPGAPGCTLESTTYRDRFAEFDGRGVTVRGVSTQRPDQLRAFSEHAA
                     LPFALLSDSDLALTAALRLPTFRAGGVDRLKRLTLLVDPGQVIRAVQFPVTDPAGSVGE
                     ALAHLDELA"
     misc_feature    complement(34790..34804)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.57"
                     /tool="antismash"
     gene            complement(34852..35652)
                     /locus_tag="HUW46_RS00365"
                     /old_locus_tag="HUW46_00075"
     CDS             complement(34852..35652)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (14-248). E-value:
                     8.8e-21. Score: 66.5. Matches aSDomain:
                     nrpspksdomains_HUW46_RS00365_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660272.1"
                     /locus_tag="HUW46_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00075"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_215545343.1"
                     /sec_met_domain="PF00561 (E-value: 3.9e-12, bitscore: 45.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.7e-14, bitscore:
                     53.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQVFHEEFGSGVPVLALHGWTPDHRMMSGCLEPVFAERPGYRR
                     LYPDLPGMGKSPGGSARGSDDLLAAVSSFADEHLGAEPFLLVGESYGGYLARALVRERP
                     GQVRGMALICPIGTEPEHARRTLPPHTVLRSDPALIASMDAAEAADFTEIAVVRSPEIL
                     ARYRAEVAPGLALADETTLARVRENYTLSVPPESGPAYERPVLVLTGRQDSITGYEDQY
                     ALLGHYPRASFAVLDRAGHNLQLEQPALFGALLAEWLDRVAESG"
     aSDomain        complement(34909..35610)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HUW46_RS00365_Abhydrolase_1.1"
                     /evalue="8.80E-21"
                     /label="HUW46_RS00365_Abhydrolase_1.1"
                     /locus_tag="HUW46_RS00365"
                     /protein_end="248"
                     /protein_start="14"
                     /score="66.5"
                     /tool="antismash"
                     /translation="PVLALHGWTPDHRMMSGCLEPVFAERPGYRRLYPDLPGMGKSPGG
                     SARGSDDLLAAVSSFADEHLGAEPFLLVGESYGGYLARALVRERPGQVRGMALICPIGT
                     EPEHARRTLPPHTVLRSDPALIASMDAAEAADFTEIAVVRSPEILARYRAEVAPGLALA
                     DETTLARVRENYTLSVPPESGPAYERPVLVLTGRQDSITGYEDQYALLGHYPRASFAVL
                     DRAGHNLQLEQP"
     gene            complement(35708..36544)
                     /locus_tag="HUW46_RS00370"
                     /old_locus_tag="HUW46_00076"
     CDS             complement(35708..36544)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076426.1"
                     /locus_tag="HUW46_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00076"
                     /product="aldo/keto reductase"
                     /protein_id="WP_215545344.1"
                     /transl_table=11
                     /translation="MTSPTTVPSIRLTGGVPIPQFGFGVFGIEPDRTADAVALALDAGY
                     RHIDTAQMYRNEQGVGAGIKKSGVPREEVFVTTKLANDAQGHDNAITALEGSLRRLGTD
                     YVDLYLIHWPLPAKDRYVKTWQAFDEILKAGKARAIGVSNFSPAHLDRLAGETGAVPSV
                     NQIELHPYLQQAELRRYHEEHGIATEAWSPIAQGEVLGDEVVTRIAAAHGRTAAQVVLR
                     WHLALGHIVFPKSSSPERIRENIDVFGFALSDEDMRALGGLDRGRRTGPDPETFDG"
     gene            36774..37937
                     /locus_tag="HUW46_RS00375"
                     /old_locus_tag="HUW46_00077"
     CDS             36774..37937
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670794.1"
                     /locus_tag="HUW46_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00077"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_215545345.1"
                     /transl_table=11
                     /translation="MPDEAAPLHVLLVEDDDGDALLVEEFLADSAAPITLDRVATMADA
                     VGAPVTADCVLLDLNLPDAVGIAGVTRVRRHAPGTAVVVLTGHNDEETGIAAVAAGAQD
                     YLVKDQVDGLLLIKALRYARERKRAEQVEQQLLEQQLLANENSRLERGLLPTPLLADSH
                     LALTTRYRPGRDGSLLGGDFYDAVELADGTVNVIIGDVCGHGPDEAALGVALRIAWRSL
                     VLAGLASGEVLTMVERVLRHERIRSVFATVCMVTVAADRGSLRMSLAGHPPPLLVTGDG
                     GELLPNDRLGVPLGVVDDARWEPLEVPLPPEWSLLLYTDGVFEGRVEEGIERLGHEEMA
                     KLVLGILGREPEHGKVLDELIATVERLNRGPLDDDVALAMLTHRSGR"
     gene            37934..39481
                     /locus_tag="HUW46_RS00380"
                     /old_locus_tag="HUW46_00078"
     CDS             37934..39481
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229350.1"
                     /locus_tag="HUW46_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00078"
                     /product="sensor histidine kinase"
                     /protein_id="WP_215545346.1"
                     /transl_table=11
                     /translation="MTDDHVRRWSLRRWATLLGFAEAVLLVAALVGGGVALKTFDDART
                     RLVDQTGPELLQATTLSTGLLNQETGLRGYLLTGQGDFLTPYEQGKRQEAVAVAELRRL
                     GAVPGTEAGADLDAVQRAAEAWRAEARPDAPPPQADRGKGLFDAVRTALDTQQRHLAAA
                     RDAARESLADANTILTTMLVVIAALVLLLFLLVYLGFRRTITRPVIRLAEQVRAVSADD
                     LRGEVRGDGPREVRQLAEDVEAMRRRILGEVAELERAHELLDTRTHELERSNSDLEQFA
                     YVASHDLQEPLRKVASFCQLLQRRYSGQLDERGEQYIEFAVDGAKRMQNLINDLLSFSR
                     VGRRAGDHVVVDTGALLDQALANLDPVVEETGAVLTRGALPEVRGEATLLTAVLQNLVN
                     NALKFRGEAPPEVRVEAERDGAEWVFSVTDNGIGIDDEYAERIFAIFQRLHAKSAYPGT
                     GIGLAMCRKIIEYHGGRIWLDTTAAEGTRFRFTLPALEEPEAVEPVENADHVKSEEE"
     gene            39478..39915
                     /locus_tag="HUW46_RS00385"
                     /old_locus_tag="HUW46_00079"
     CDS             39478..39915
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634700.1"
                     /locus_tag="HUW46_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HUW46_00079"
                     /product="response regulator"
                     /protein_id="WP_215545347.1"
                     /transl_table=11
                     /translation="MTESLDPIDILLVEDDPGDVLMTKEAFEHHKIRNTLSVVADGVEA
                     LQFLRREAPYEDAPRPGLILLDLNLPRMDGREVLSEIKASPDLRTIPVVVLTTSEAEED
                     ILRSYDLHANAYVTKPVDFDRFVEVVRQIDDFFVTVVKLPR"
     gene            complement(39989..40981)
                     /locus_tag="HUW46_RS00390"
                     /old_locus_tag="HUW46_00080"
     CDS             complement(39989..40981)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HUW46_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HUW46_00080"
                     /product="hypothetical protein"
                     /protein_id="WP_215545348.1"
                     /transl_table=11
                     /translation="MTATAVVAERSPRARVGWGDLIGVTARQHRLMLVGTGVLVLAAIA
                     GMLWVSVEVAGQGDARIGLPGVRQVSDVGELLLAGVLGFSGLVAVFWAAPLLSKEYEQR
                     THLLVWSQDVSPLRWLAVKTTVLAAVAVAFSVALGVTAEFMMHRILEMPSQYPAFNLFR
                     SPYFDDVALTQAAYALFGFALGLAVSAICRRTVVSMGVTAALFVGVRAGIERFVRPYFQ
                     SPVRQTSPLGVEGPATNELPPNTLTVDSGYLDGAGTTMDYPRSCSGSYRSAGEYYSCLR
                     QNGIVAHYRDTQPPERLGFFQLAEFGLFVVLAAVLLVVALRVVRRMARV"
ORIGIN
        1 agagacggcg tgcggcgcgg gtggccgagc ggcttgacga tgccctgaag gtggctttcg
       61 gggcgccaga tgccccgaaa gccaccttca gggcgccgag cagcgagccg tcgagccgag
      121 cgcgcctatg cttctatgtc cacatcggac agagggatgg cctggcaggt caggcagctg
      181 cccgccacag tgtccactgt ggacaaatgg gtgatctcgc cccgccgcac ttcgacgcgg
      241 caggattcgc acaccccggt gcggcagccg ctgccgagcc ggatcccggc ggactcggcc
      301 gcgtcgagca gggtgccgga ctcgggcgtc cagacgattt ccctgccgga gcgggtgaac
      361 cgcacggtcg cgggcgacag ggtttccggc acctccacct cggtgaagaa ctcctcgccg
      421 aagatgtcga accggtcgac cccgcgcgcg gcgagctgct cggtcagctc ggccatcatc
      481 gccgcgggcc cgcacaggta gaccaccggc ccggtggcga ggaactcgtc gagccgctcg
      541 tccacggtga accggccggt gccctcgccg gtcacgtgcc ggaccagctc gacaccgggc
      601 aggccagcgg ccagctcggc gaggcggtcc gcgatcgggg tctccccctc ctcgccgcga
      661 tgggtgtaga ccacgcgcac ccgcggcggc accggcctgc cctcggcgag cgtttccagg
      721 tacccgagga acggcgtgat cccgattccg ccgccgatac acagcacggt gcggttcccg
      781 ccgacgggcg gggtgaacgt gccggtcggc gccttcagct ccagcacgtc ctcgccggcg
      841 gtgtgcaggt gcgccgacat gcggccgccg atgttcttca ccgcgatgcg gaggtcgccg
      901 gtcccgttcg tcagcgagta cgcgcgctgg gtgcccagtc gcggcgccct gaccgtcacg
      961 ttctggccag gccggaactc gggcagctcg ccgccgtcgg cggggcgcag ggtcagcgac
     1021 aacgcgccgt tttccaccgg ggtccgcccg gtgacgacga acgcgcgcca gcctgcccag
     1081 ttgcccgccg aggtctcggc gtccctgacc aggtcgcagg cgaccgcccg cagcggcacc
     1141 gatccgctga tcgggtcgcg cctgcggtcg gacagcgcgg cgttgatgtt gctggtccgc
     1201 cgtcccagcg cggcgaggcc gggcgtggcg agcggggcct ggtcgtccca ccagccgtgc
     1261 tcggcgatca ccaccctgtc gtcgaggctg tcgtcgagcc gcacgcgcag ccgcgcttcc
     1321 ccgtccggcg tgcggacgat cgcccagtcc ccttcggcga gaccgcgtcg cgcggcgagc
     1381 gccgggctga tgtcgacgcc gggatcgggg gaacggcgcc gcagcgaggc gagcgaacgc
     1441 agcgacgaat gcgtgtagtg gccgttcttc gcggtggtca gcacgtacgg gaacgctgcg
     1501 tcgccgggcg cgatcccgtc cggttcgacg aaggtgggca gcgcgggctg cccgtgccgc
     1561 cgcagcagcc ccgaatacag ctcgacgcgg cgggattcgg tgccgaaccc ggtcaccgtg
     1621 ccgtcggcca gctcggtcgc gtacttccgc tcgcgctggt cgatcggcac cctgatcccg
     1681 ccggggttcg cccgcagttc gtcgacggtg aggccgagcg gggcgagctg gtggttccgg
     1741 cccgcgtcca cgtcgccgcc gaagaaatcc cccgacatgc cgagcctcgc cgccagcccg
     1801 gtcacgatgt cgtagtccga acgggactca ccggcgggcg ggatcatccg cggccggagc
     1861 tggaccagtt cctcgccgtc cgcgctgttg tcgaagccga tcatcaaccc gtctcgctcc
     1921 ggtggcgcgc acaccggcag caggaagtcc gcggtcgccg cggtcgggtt ctcgaacagg
     1981 tcgcactgca cctggaactc cagcgcgcgc agcgccctgc ggttctcgtc ggcggatccc
     2041 tgcgacacca ccatgttcgc gccgaacccg atcatcgcgc gcacgcggta cggctcgccg
     2101 tccagcacgg cgcggcggaa gtcccgcgcg gtcacgtgcc cctgcgcggg cgggccgagc
     2161 ggcatttcct gtttgcccaa cgccttttcc cgcacctcgg cgggcagcgc ggcgaagtcc
     2221 gccagtgggt tcggccggtg cttgtccagc cagcggatgc cgcccgcgcg gtcgtagctg
     2281 ccgagcagcg cgtacagcac gctcatcgcc cgctcggtct gcgtggcgtt ggtgtgctgg
     2341 ccgaccccgg tccacgagta gtaggcgacc cgccggtact tcgccagcat cgcgtagaac
     2401 gcggtgacct cggcgagttc gatccaggtg gtctcggcga ccttggcggg cgtccactcg
     2461 gccacgtgct cggcgagcag atcgaaggcg gggcgcacgg cccgcccgtc ggcgagccgg
     2521 aaccggccgt gcagcgcgac gtcgtgcggc gcgctcagcg cccggctcgt gtcgtagcgc
     2581 cgcggtgccc cggaagcgtt gtcccacacc aggaatccgc cgttctcccg gaccacgtcc
     2641 ccggtctcgg agtcgacgag gaacggcccg ttggtccagg accggacgaa ctccgcgtcg
     2701 tagtgctcgc cgccgatcaa gtggttgacc gccccgagcg cgagcgccgc gtcggcaccg
     2761 ggccggatgc gcagccactg gtcggcctgc tgcccgctcc cgccgcgctt cgggtcgacc
     2821 accaccacct tcgcgccgtc gcggcgcgcc tcggcgatcg cgctggcctg ggcgagccag
     2881 gtgcgcgcgg ggttgtggcc ccacagcacg atcagctcgg ccgcgcggta gtccggcgtc
     2941 ccgatgccct tgccgaaggt gaacgcgtgc gcgaagttct tgtgccagcc gcagatctcg
     3001 gtggcgtaca cggtgttggg gctgccgaag gactgcacga accggttgac ccactcgctg
     3061 ccgtcgacca tcggcgtgcc gctcggcgtg gtcaccgcga acgcgaccga ctcgggcccg
     3121 ctctcctcgc ggatctccgc gagcctgccc gcgatctcgt cgagcgcttc gtcccagccc
     3181 acccgcaccc agccgggatc ggcggcgtcc ttggggttcg tccgcttcag cgggtgcagc
     3241 agccgcttcg ggctggcgac cagctcgggc atcgccctgc ccttcgcgca cagcgcgccg
     3301 ccgctcgggt gcccgtcgag cggctcgacg gccagcaggc gatcgcggtc gaccaccgaa
     3361 acggagccgc agtgcgactt gcagagcgtg cagtacccgg gaactcgctg aacacccata
     3421 ccgacacggt acctaccgga tcatgctccg gacacgggtt tccgggcggg gtgcgcaccc
     3481 cgcccggaaa ccgcgcccgc gccgaaaagg gctcaggtga tggagaagtc gtcggcgtag
     3541 accgcgccct ggccgtacca gccgtgcgcg aacaccgtca ccgcgcccga ggcgccggtg
     3601 gtgaacggca cgctcagctg ggtccagccg gtcgacgagg tccacgtgct cgcgctggcg
     3661 ccgccgctca ccccgaggta ggcgtagttg ccctgcaccc aggctttgag cgtgtacgcg
     3721 tggttcggct gcagcgcgac gttctggcgg acctcaccgg tctgcgaacc ggtcgcggcg
     3781 agctgtagcg cgtgcgcgcc ggaatgcgcc gggctggcga ccaccgaggc ctcaccgctc
     3841 cacgggctca gcgcgccggt ttccagcccg ccgttgacga ccgagccgcc ggggttcgcg
     3901 ccgttgacgg tgagcgtgta ggtggccgtg cgggtcacgc tcttgccgcc ggaggagccc
     3961 gtgccggtca ccgtgatcgg gtaggtgccc ggcggggccg ccgcggtggt cgagaccgac
     4021 agcgtcgcct tggcgcccgc ggtgaccgtc gcggggctga ccgaggcgct gaccccttcc
     4081 ggcgcgccgc tgacgctgag cgtgacctgc tgggccgcgc cgttggtgag cgcggtggcg
     4141 acggtgggcg tgaccgaacc gccggggtcg accgcgcccg aagccgggtt caccgcgacc
     4201 gaaaagtcgt ccgcgggctg gctgccgccg ccggtgaacg gggcgaaggt cttgctgaac
     4261 tgccaggtgt cctgctggat tccggagcag ctgtcggacc ccttcgtgcc ggggcagccg
     4321 ccgttgtcgc gctgcaacgc ccagaacgac agcgtgttga tccccttcga caccgcccag
     4381 tcgtagacca cgggcccgtc ggcggtggtg aaggtctccg cggggccgaa gtcgtcgatg
     4441 ccgatcatct cggtgacccc gaccatcgcc cacagctgcg cctgggtctt gcccgggtag
     4501 agcgcggcaa gctgcgagac cagcccggtg gccgcggtct tggtgtcctc ggccatgttg
     4561 tgcgcggcgt tgtcgtagta gtcgaaggtc atcaggttga cgacgtccac gcgcgcgttg
     4621 ttggacaccg cgttttgcag cacggcgagc ccggaatcgg cgggcccgtg cgtcgtggtg
     4681 ggcagagtgt aggagaactg cacggagcgc ccggtggacg ccgcccagtc ctgcaccttc
     4741 ttgatcgcct tgttccggcg gtcgatcccc gcggtgttcg tcagcgaatt gtcctcgatg
     4801 tccagatcga tccgcgggat gtcgtaggtg gtgatcacgt tttcgaacac cgacgcgatc
     4861 gagtccacat tggtgcagct gtccgcgatc tcggtgccgg tgttgtccgc ggtgtagccg
     4921 ccgaaggacg ggatgacgtc accgccgcgt gcctggatgg tgtcgatgtc ggcgccgaag
     4981 gtgccctgcc cgatcggcat gcccgcgtcg ccgttccagt aggcggtgca ggagcccttc
     5041 gtcgcggcct gcaggaaggc catggtcagg tgcttcgcgc ccgactgctg cgagagcgcc
     5101 gccgggctct ggccggtcca cgcctcgaag tacggcgcga agacgtgcga tggaagtgcg
     5161 gtggccgcgt gtgcctgccc ggcacccgcc acggcgagcc ccgcggtgac gacgacggcg
     5221 gcggtcagcg aactgaggtg tttcaggatc ggtctgtacc cacgcatgtg cgctccatga
     5281 gcaaaggggg cgaggaggcg ccgggcctcg gcgccgtgtc gaccagaatt ggactagacc
     5341 actgccgtgt caagcgatgc ggccaagcgg ccgacgacca aagtcgggcc cttctcacca
     5401 tgcgcgcatc gtgacggaaa tcgtgcacac atagttgcta ttgcgtacca acgattcgcg
     5461 tcgtctaatg tgggaatgct gatcgaagag cggcttctcg aagagcaacc gtgatgcgcg
     5521 ccaagggaat cggagcggtg ctcgccgccg tggccctgtc ggtttcgttc ggtgtcgcgc
     5581 ccgcggatgc ggcgccggaa acgattctcg gattcacacc gaagcattcg gccgcacaac
     5641 gggcggccga acagacgttc tccggcgtcc tctcccccgc tgtcgcccgt gagctcgacc
     5701 gcgacctcgc ccacgagacc ggcctcgtgt cgacgccagg cgactacaag cggatgcgga
     5761 aggtggtgga ctacctgcgc tcgtacgggc tccagccgca ggtgcacacc tactacgtct
     5821 accagtcggt accccgccgg atcgaggtca cgatgacctc gccgcggcgg atcaccttgc
     5881 ccaccaagga accctgcctc gcggtcgaga cggactgcgc gaacatggtc gtcggctaca
     5941 acgcgctgtc gccgtccggc gacgtcaccg cgccggtcgt ctacgcgaac tacgcgaccc
     6001 ccgcggactt cgccgagctg gacaagcgcg gcatcagcgt cgagggcaag gtggtgctcg
     6061 cccgctacgg cgcgaacttc cgcggggtga agagcaagct ggccgccgcg cacggcgcga
     6121 aggccgtaat catctactcc gacccgaagg acgacgggaa caccaacggc gcggtctacc
     6181 ctggcgggcc gtggcgcaac cccgacggca tccagcgcgg cagcgtgcag cagttgatgc
     6241 agtacggcgg cgatccgctg acgccgggct gggcgtccac gaaggacgcg ccgcgcatcg
     6301 accccaagga ttcgaacatc gcgccgatcc cgaccacgcc gatctcctac gcggcggcgg
     6361 aaccgctgct caaggcgctc ggcgggccgc aggtgccggc gaacttccag ggcgggctgc
     6421 cgttcccgta ccacttcggc cctgggccga ccacggtgcg cgtcaacctc gacatcgcct
     6481 acgagacgaa gccgctgtgg gacgtcaccg cgaccgtgcc gggccgcagc cagcccgacc
     6541 agaccgtcta cgtcggcgcg caccgcgact cgtggaccta cggcagcgac gacaacctct
     6601 ccggcaccga ggcggtgctg cagatcggcc gcggcatcgg cgcgctgctc aagaccggct
     6661 ggcgccccga acggtcgatc acgctcgcca cgtgggacgg cgaggagtac gggctgttcg
     6721 ggtccaccga gtacgccgaa cagatgggtg accggctcaa gggcgcggtg acctacctca
     6781 acatggacgg cgcgggcggc aagcacttcg gggccgcggg cacgccctcg ctggaccgga
     6841 ccatccgcca ggtcacgaag gacgtgccgt ggccgggcac gaagggctcc gcctacgacg
     6901 cgtgggtggc ggaccacggc ggaaaggtcc cgccgatctc ccgcctcggc agcggctcgg
     6961 actacacggc gttcttcgac cgcttcggcg tgccgtcggc caacatcggg tccagcaccg
     7021 acagcggcaa ctaccactgc tcgtgcgaca acttctggat ggaggaccac tacatcgacc
     7081 cgacgtggca gtaccacgtt gccaccgcgc agacggtcgg gctgaccacg ttgcgcctgg
     7141 cgaacgcgga cgtcctgccg atgtactaca gcgactacgc cgccgaaacc ggcgactacc
     7201 tgaccgcgtt cggcaagcag cagtccactg tggacgtctc ggggctgaag gagcgcgcgg
     7261 cgcagtggca gcgcgcggcc aaggcggcgg aggacagggt ggccaaccgg ctcgcgaccg
     7321 gcggcgacgg cccgatcgag gggatccgga acagcattgc cagcaggctg ttctcggcca
     7381 ccgaacggca gttgctcacc gacgccgggc tgcccggccg cccctggtac cggcaccagg
     7441 tctacgcgcc ggggatcaac gcgggctacg gcacgcaggt cctgcccggc ttgcacgatg
     7501 ccgtgctgga acgccacaac ccggcggagg cggcgacggc cgccgactcg ttcgacgcgt
     7561 cactgcgcaa ggcgaccgcc gtggtctccg ccgcaggctg gtaaccctcg cccgcggcgg
     7621 gccgcttcgc tcctggcgaa gcgttctgcc cgcggcagac cgctcggtgc cccgaaagtg
     7681 aacttcgggg cgccggattc cccgaaggtc actttcaggg caagcgcgtc gcggtggccg
     7741 agcgtgcgag gggtcgattc gcgacgccta gcgccccgaa ggtggccttc ggggcatgcc
     7801 cggcgctgcc cgcaccctcg cgagggccga gaaagtggcg ctggattccc cgaaggtggc
     7861 cttcggggac cagtcgaggt gatctcccgg aaccaccgcg ccgcgcaccc gatgccccga
     7921 aagtgacgtt cggggcacac caagggccgc cgggcatccg gcacggggtg cgaaaatcgg
     7981 atcgccgcgc tgccgggaaa ttcgtttccc tattgagaca gtgtccgcac cagcgatttc
     8041 gcgttcatcg cgtcgagcgc gtgagaaagg cggaacacgg acccgttcgg cggtacccgg
     8101 cggccactcg ggcgaagctc ttcgctccct gtcgaccatt tttcgggaaa caagcggccg
     8161 atccggtcga cttcagccgt catacgggga agcacgcagt aggggaaccg ccgcgaagaa
     8221 atggccgcta gcggccattt cgcacaccgt gagaccgcgc gcggcccatc gacggcggtc
     8281 ggatgtctat agttggcgca ccgaaaccgc cgcggcaggg ggcacgtgcc gctcggacga
     8341 agggggacga tgcccatcga tgcgcatcac ctgtccggtc tgcgcgccat caccggcgga
     8401 ctcgtcgaag aactgctttc ccggccaggc ggggaaaacc gggcgctgcc cgtcgtggtc
     8461 gcgatcggcg cacggggcac cggcaagacc gcgctgctca ccgaactggc cgcccgctgc
     8521 gaaagcgttc cgcacgcgca cctggatttc gagcggcacg actgggaaaa cgttcagccg
     8581 agggaacttc tcggccacct cgccttcgac ctcggcaggc actggcggca gttcggcagg
     8641 ctcgccttcc cccgcctctg gctctgcatg ctcgtgctcg gcgcaccggt ggagatcacc
     8701 gaccggcgcg cggcgctgcg gaagctgcgc gaactgctgg cgcagaacca gccgctggag
     8761 cacaaccgcg aagccatcgt cgacgtcgtc aagctcgcgg gcggagtcgc ctccgggcgg
     8821 agcctccccg gctggaacga ggcgacggac ctgctgctgc gcggtctgag ctggtacgac
     8881 cgccgccgtc tggtcggcaa gatcaaggcg atcccttccg gggcgggaaa ccacgaggac
     8941 ttcctgatcg agatcgccaa gcacgcgcag ggcgacgagg aggaccgcgc gggcgtcgac
     9001 gcgaccttct gcgacgcctt cctcgccgat ctgcggcgcg attactccgg gatcaaccgc
     9061 gcgcgccgga cgctgaacag catggtgctg ctggacaacg cgcacacgcc gggcggcagg
     9121 gcgttcctgc gcgcgctgga cgaggcgcgc cgccgctgcc ccgacgaggc ggatccgctc
     9181 gccgtgatcg cgaccagccg gacctggaac ccggactgga acgagagctg gacgctgctc
     9241 accccgcacc acaccggtga ccgcgaaccg gcgagaccga ccagccaccg gacgaacggc
     9301 ctgcaccggc ccacgccccg ccaaccgtcc gatgtggagg atgactgggc cgcggggtca
     9361 ccggaaagcc gctggcatcc ctggtacctg ctcgaactgg gcacgttgtc caaagaggac
     9421 accatggatg tcgcggccgg gcacgacatc caccccgcct cccggctccc ccggttcctg
     9481 caccggctga ccgacggcca ccccggggcg atcaccgagg tggtggcgca ggtcgcgcac
     9541 cgctacgact ccgcgaaccc cgccctgctc cggagtgcgc tgcggaccgc ggtacccggc
     9601 caggaaggcg gcgagtcgac actgctcgcc gagatccgcg accacctgct gcaggacttc
     9661 cccgaggcga gccagcagga cctgatcacc gcgagcgccg cgatcgacgt ggaaatgctg
     9721 ttccacaagg aaatactcga tctgcgcaac ccggtcggcg aaggcgcgct gttcaagtcg
     9781 ctcggcgagt acctgtggct gcgcgccgaa ccgggcgagt cgccgcagta cgtgctgcac
     9841 ccgtggctgc gccggatcct gttgcaggag ctggcttccc gcgccgacga ccacccgctg
     9901 agctgggtcg aggtgcacac gcggtgccgg gacttctacg agaagaacgg gcggatcgtc
     9961 gccgcccgct accacgacct cgcgctggaa gacgtcggcc agacgatcgt gcacctgcgc
    10021 aggccgttcg actccaagca cgccgagttc gacgtgcccg ccgccgaatc gtggctggcc
    10081 gaactcgacg tgatcacggc ggcaccgaac cggctggaca aggacgccga cccgtacgac
    10141 caggtgcagc ggctcgtcgg cgagttcgac gacgagctgg aaaccacctt ggcctggctg
    10201 gtcgtcgcgc tctggatctc gcgggatccg ctcggcgatc ctggccggac gctggactcc
    10261 accatcgaaa gcagtttcca ccacctggca cagggcagag gacgagggtc gatgctgttg
    10321 cacgaacgcg cggagcggta ccgatgatcg gcaggaaggg gaaaaccgag ggcggcacga
    10381 tcctcccacc gcggcccacc tggtcgaaat ggctgtggct ctccggtggc gtgctgctgg
    10441 tggtggtggc ggtggcggcg atcatcgtcg tccccccttg gatcagcgaa gcggggctca
    10501 cctgcgacgg cgcggtgcgt caacgcggcg agcactcgga atgcacggga ccgaccgacg
    10561 gttccttcgt gttctccccc gacttggcca ccgtcgaaca acgcatccac accgaaaacg
    10621 acgcggtggc ggcgtcgggg aagccgtacg tcaccatcgc ggtcttcatc ccgatgacgc
    10681 tgaccgagca cgacatcctg tccccggaat gggttcgcca ccagctcgaa ggcgcctaca
    10741 tcgcacagcg ccgcgcgaac accactcagt cctggggcag ccttccgctg gtgcgcctgc
    10801 tgctggcgaa cccgggcagc cagctcaagc agtgggagcc ggtggtggac gacctgctcg
    10861 gcagggtcca gtccgagcac ctggtcgggg tcaccgggat cgggctgagc ctggacaccg
    10921 cgcgcgacgc gatccgcaag ctctccgacc acaaggtccc ggtggtcgcg tcccacctcg
    10981 ccgcggagca gttctccgag atcccgggat tcctgcgggt ctcgcccacc agcgccacct
    11041 acggcatggc gaccgcgaac ttcgtgaagc cgacggcgaa gacggcgacg atcgtgcagg
    11101 accagaacgc gggcgacctc tacccgaaga ccctcgccga cgggttcacc gcgaagttcg
    11161 tcgacgacgc gcaccggatc gtcggcagga cggaggccta cgattccagc cttcccggga
    11221 tcgagaacac cttcctgcag atgatgccga acatctgcgg taacgcaccg gacgtggtgt
    11281 acttcgcggg gcgcgaggac cacttggtct cgttcgtcgc ccagctcgcg caacgaccgt
    11341 gcctcgacag gcacatcacc gtgctgaccg gggacctcgc gctggtcggg ccgcccggtc
    11401 aggagatgcg ccgcggcctg caggccaatg tcaccgtgat cgcgccgggg ctcgcccatc
    11461 cgcaggcgtg gaccgccgag cccaaggcgt tcaacccggc ggcggtcgcg agcttccacg
    11521 aaacgtcctg tgtggactgc ttcgaagccg tgttcccgaa ggaacgcctc gacgacggca
    11581 tcgcgatcct cgcgcacgac gccgtgctca ccgtggtgtg ggcgattcgc ggcatcccgc
    11641 gggtctcgcc cgcgcaggtg accgccgaag acgtgctgca ggcgaagaac cgtctgcacg
    11701 accggttcgc cgtccccggc gcgagcggca tgatctcctt cgacgaccgg ggcgacccgg
    11761 tgaacaaggc ggtgccgatc ctgcgggtgc gcctcgacaa cacccccgag ttcctgcaac
    11821 tgtccacacc gggcggctga gccggtcagg acgcctgccg gagccccgcc agcgcggtgg
    11881 ccagcagccg gtcggcctgc gcgggggaaa cctgttcgcg cacccacgcg accgcactga
    11941 tcacagtgga cacatcggcc gcggtgacgc cacgccggac ggcacccgcc tcgctcgcgc
    12001 cggcggcgat ccgcccgccg atcgactcca tgcggcggca cgcgtcgtgg aggtctgacg
    12061 ccctgtcgtc gatcccggcg acgagcaacg cggccagccc ctggtagatg gccgcgtggt
    12121 ccaccgccgc gcggatccac gcctcgagcg cctcgccggg cggctcctgc gcccgcaacc
    12181 gctccccctc cgcgaacaac gcctcgttcc gttcgtgcag cagcgcgtcg atcaaggcga
    12241 gcctggtcgg gaagtgcccg tagagcgtgc cgatcgcgac gccggactcg cgcgcgatcc
    12301 cctccagcgg tgcgctggtc ccgcgttcgg cgaacgcggc gtcggccacc gagaggagcc
    12361 gctcgtagtt gcggcgcgag tccgcccgtc gtggccgttt cgtgggatcc atcgtcgact
    12421 ccgtcaatct gaggtaccct caggttaaat ttcgagggcg cctcatctta gcggggcgcc
    12481 cgggtaccgg aaggcatgcc catgatcctg gtgaccggag cgaccggcgc gatcggcaag
    12541 cacctcgtac gggagctcga ccaagcggga accccgttcg ccgcgttcgt ccgcgatgag
    12601 gccaagggac aggcgctcgg ctgtgaattc atcgtcggcg acttcggcga tcccgcttcc
    12661 gtcgccgccg ccatgcgagg tgtcgacgtg ctcctgctca acggcaacgg cgcgctgccc
    12721 gtcgagggcg agcagccgat gatcgcccag cagaaggccg tgatcgacgc cgcgcgcgac
    12781 gcgggcgtct cccacatcgt gaagatttcg gcccagggcg ccagggaagg cggaaagctc
    12841 tccaccggcg ctcactggga gatcgagcgt cacctgaagt cctccggcgt cggctggagc
    12901 atcctgcgac cgaactcgtt catgcagaac ttcatcaccg gcgcggcgac gctgatcgag
    12961 agcgggaccg tccagggccc gttcccgcac agccgggtgc cctacgtcga ctgctacgac
    13021 atcgccgcgt gcgcggcggc actgctcacc gcggcgggcc ccaccagccg caccttcgcc
    13081 ctcaccggcc cggaaagcct tacccagcga gaaatcgccg accggttcgg catcgcgctc
    13141 ggcacaccgg tgacctctgt ggaactgagc cccgaagaca tggtggccgg gctgcgaagc
    13201 caggggctcc cggaatggtt cgcgcgcgac gccgtggccc tgtgggccga cgtggcggcg
    13261 gaccgcactt tggcgaccac gacggggacc gtcgaagagc tcaccggacg ggcaccgcgg
    13321 acgttcgacg agttcctcac cgcgaacctc gccgcgtttc gctgaccgtc atcgccacgg
    13381 gcagtccgga tggtgttcgt aggcggcggt gagctggtgc agggtcgtat cacggaaccg
    13441 ccgggcgtgg gcgaccgagg cgctccggcc tcggtcgtgc tcgtaggtgt gccgctcggt
    13501 tatcgtgacc aggtcgtcga gaccggcgag caggttgtcg agcgcttcac ccagcgagtg
    13561 ccgctcgttc gcgaacatca ggtgcaggaa acccgttcgc tccaacacgt cttcgtccga
    13621 gagccactcg gtcgtcctct ccacagtcgt ccccttcgtg ccgtgttcgt gcggcggcca
    13681 ccgagccccg gcgcctgttg aggacaccgg ggcccggtcc cacgtggtac ttggactatg
    13741 taccggtatt accgctggcc gcaatgaccc gatcgagtac tggcgggaat atggtgccgt
    13801 tccgatatga tttggtacat gggtagtacc aacgccagta caccgcgggc gcgagcgctg
    13861 gcggacatgt tgaacgccgt tctcgaaaag tcgcggcact cgcagcgcag catcgccaag
    13921 ctcatgggct acagccacgt gacggtcggt cggtggacgc gcggcgaagc gacaccggac
    13981 gatgtcaccg tcgcgacttt cctggcgcat ctcggcatcg tgggcgaaga acgcgaccgg
    14041 atcctcgaag tcgcgagcgc gccggacggc ggcgactggc tgaccgtcgg ccccggtggg
    14101 atcccgagcc agctggccgg ggtgatgaac ctcgaacgca acgccgtgcg gctcacaaac
    14161 tggtcaccgc tgttcgtccc aggaatgctg caaacacagg cttatgcgag ggcgatcatc
    14221 gaacgctcgc caaggatcac ggacagcgag atcgaccacc tcgtgaccgt ccggctcggt
    14281 cggcaacacg cgatctcgcg cgacgaagct ccactcaaga taacgtcgtt cctcggcgtt
    14341 cccgcgctcc gaggtgggat cggcggcacg agcgtgatgt gcggccagtt gcgctacctg
    14401 ctgaaggcgt cgaggttcga gaacgtcgac cttcgcgtcg ttccggtgga cggcgagtgg
    14461 cacaacggca tcatgggccc gttctccctc tacgattcct cgggcggcga gccgaccgtg
    14521 ctgcacatcg agcaccatcg caccggtgcg ttcatctcgg atccgagcga tgtccacgcc
    14581 taccaggaag acctggtcaa ggacctgcgc cgactggcgt acggcccgga cgaaacccgg
    14641 gagctgattc aggaagaact gaagaatcga gaggacgcat gaaaaacaag gtgccaccgc
    14701 ctaggtggcg cacgtcgagc tacagcggcc agcaaggcga ttgtgtcgag gtcaagctcg
    14761 acacggccat cggcgtgcgg gacaccaagg accgaaccgg aggagacctg gacctccatc
    14821 cctcggcctg gaacgcgctt ctgacgcgac tccgctgaac accgagcacc cccggcagac
    14881 ctgttgactg ccgggggtgc ttcgcgtccg ggccgaaacc cggcacgctt ccggggtatt
    14941 ccggcccttt aaataggtgt cgccaccaag accgttttgt tgccggaacg cccggttcgc
    15001 cccgttttcc gggcagtggt cggtttgttt acaaccttgg tcggtagcgg aaggttttcg
    15061 ccggatccga aggtgtgcgt gttaccccgt gctccaccgg aattctggag aaaccatgcc
    15121 ttccaggaaa tccctcgccc tcttcgccgc cttctcggcc gcggcgatga cgaccggcgt
    15181 ctgcgcgcag acggcgtcgg ccgatccgct cgcgttcgcg cagctccagc agaactcgat
    15241 cgaccaggcc acccaggtca cgaacacgct cggcgcctcg tccggcgggt tctacctcga
    15301 ccagggcaag gccgtggtca acgtcctcga cgacaccgcg gcgcagaccg tgcgcgacgc
    15361 gggcctgacc gccaagaagg tcgcgcacag cttcgccgcg ctgaccgcgg ccaaggactc
    15421 gctcgaccag gtgcacgacg tcccgcagac cgcgtggggc atcgacaccc gcgccaacca
    15481 ggtcgtggtg acgatctact cggcggccac cccggcgacg gcggcgaagg tcaccgccgc
    15541 ggccaaccgg ctcggcgacc gcgccaggat cgagcacgaa accggcaagc tggagctgta
    15601 catcgccgac ggcgacgcga tcaggaacag ctccggccgc tgctcgctcg gcttcaacgt
    15661 gaagaagggc agcacgccgt acctgctcac cgcgggccac tgcaccaacc tcggcggcac
    15721 ctggtccggc ggcgacgtca ccggggcccg catcgtgcac agcgactgcc ccggcgccga
    15781 ctccggcctg ctgacccgcc cgaacggcac cggccccggc cggatcaaca ccggacaggt
    15841 gatctccagg gcgggcacgc ccaccgtcgg cgagcggatc cagaagcagg gctcgaccac
    15901 cggtggcggc agcggcacgg tgaaatcggt cgaccagtcg gtgaacttcg acgtcggcgt
    15961 gctcaaccac gagttcggca cgagcgcgca caccgaccac ggcgactccg gcgggcccgc
    16021 ctacgacggc tcgaccgggc tcggcaccct gtccggcggc aacagcacca ccagctactt
    16081 ctacccgctc acccgcgagc tgtcctcgta cggcgtgacg ctggcctgac caaccctgat
    16141 ccgcgcgaag tccggccggg atggcgacat ccccggccgg accgcgtcat tcgccgcgca
    16201 tggccttgcg gatctcggcc agcttgtcct tggccgcctc gtcgcgatcg gcgatcttct
    16261 tgtccagcgc ggccatgtcc tgcccggtgc cgagcccggc cagttcggtc gacccctccg
    16321 cggtggcggc ccgcttctcg atccggtcct tcacgaagtc gaaggtgggc acgcccccgt
    16381 cggtgtaatc cgtttccgga accgacggcg tgaacgcggg cggctcggtg ctggccggtt
    16441 tcgggtcttc ggtttcactc atcgtctgct ccgtccgtat cggccggttc cggctcacct
    16501 ccgaccatag cggagcagcg acgcggctca ggtgtaccag gtgggctccg gaatttcgtt
    16561 caggagcgcg taggcgccca cttccctgcg cttgtaggcc accgggtcgt gcagggaatg
    16621 cgtccgcagg ttgcgccaga accggtcgaa gccgtactgc gacgcgctgg cgcgggcacc
    16681 ggtcagttcg aagatcttcg tgccgatctc gagcccggtg tcgatcgcgc gttgcttggc
    16741 cgcggcgatg agcaccgcga tctcgccgcg ggcggccggg gtgaggtcct ccctcggcgc
    16801 gtgcagcacc gccgagatcg ccgcgcccgc cttgtcggtc agcgcctcga cggcccacag
    16861 cttcgcctgc agatcgccgt aggcgtcgag gatgtaccac tcctgcgcgg ccgattcctt
    16921 gtcgtcgccg ccgtagggcc acggcctggt ccggtcgcgg gtgtaggcca gcgcggtctc
    16981 cagcgcgcct tgcgcgatgc cgaggtagaa gttcgtgaac acgagctgga tggcgggcac
    17041 gttgagcgtg ttgtaggtca gcgggcggaa cgccttgtcg acgtatcccg ccgcgctctc
    17101 ccacggcacc cgcaccccgg tgatgctcac gccgccggat tcggtgagcc gctggccgat
    17161 gttgtcccag tcgtcgtgga acacgatccc gtcctgtttg gacggaacga tcgcgaagat
    17221 gtggtcctcg gtaccggaaa gcacgccctc cagcacggtc aggtcggaga ccttgctccc
    17281 ggtcgagaag gacttgtgtc cgttgtagac gatctcgtcg ccctcgtcgg tgatcgtcag
    17341 gtcggagtca cgggggttga ccgcgccgcc gaagaacagc ttgttgctgg tgtacagctc
    17401 ttcgaccgcg gcgatctgcg catcggtggc caccagccgc gccgcccacg cccacaggta
    17461 gtggtagccg agcagctggc cgatcgagcc gtccgcgcgg gcgacctcgc gcgtgacgcg
    17521 gtaggcggtc tcccagctct gcccgccacc tccgtgttcg ggcgggccga gcaacgtgac
    17581 aagcccggag tccttcagta gctgcacttc gcggtgcggt gtctggttcg cgcgatcgcg
    17641 ttcgacggcg tcgacggcga gcttggccgc gacgtcgcgc gcggtttcga gccattcggc
    17701 ttcggtgcgt acggggtttt cggtcgtggt catggcgggc tttccgatct actcgggcat
    17761 ggttcgccgc cccggttttc gcgatccggg gttcaggcgc tgcggaggaa gaagatcaag
    17821 cggtacaacg acaaccggcc acgcgggcga ggtccacgtg gcggcggcgg gtcagcgggg
    17881 tgccgtccat gcgtccgagt agagcagcgg ccccctgcgg tgtcaacgaa cgtccgcgcg
    17941 ctgggaacac cgtccactca ggacggttcg gtcagcaggc cgcgaagtgc ttcggcggtc
    18001 cgctccggct ggtcctcggc gaggtaggtg tacgaatcgg cgaccgtccg cggctgcgcg
    18061 ccgagcgcgt ccgcgtaccg gcgcgcgtgc tcgatcggga acacgcggtc ctcggcggcc
    18121 cacagcagcg agacgagcac ggcggagtcc cgcaccagcc gccgcgccgc cgccgcgctg
    18181 tgccgagcgg agacgctgcc gatggccttg cgcccgtccc ggcggattcc gccgtcggtc
    18241 agcacgggcc ggacgtagcc ggtcatcgtc gcggtgtcga tcgggtactt cgccagccag
    18301 ccgtaggtgt tgcgccaccg ccaggtccgg cgatcttgtc gacggcgcgc accgcgaccc
    18361 gtttcccgcc gagcgtcgcg gccggctcca gttcgatgaa cagcagttcc ggtgtctccg
    18421 ctgacgcccc gaaggtggcc ttcggggcgc tagatgccct gagagtcaca gtgatgtcgg
    18481 gtgcgcggca cgatgatcgg cggcgtaggt ccccgaaggc caccttcggg gaccctagcg
    18541 ccactttcac ggccctcgct cacgcgcgga cagggctgcg catgccccga aagtgacctt
    18601 cggggcgctc aacgccgcac atccacccct cgcacgctcg accaccacga cacgcctgcc
    18661 ccgaaagtga ccttcagggc gctggattcc ccgaaagcca ccatcggggc acccgaaagc
    18721 ccgccgcgga ttggagcggg cggcggcagt gcggtgcgag ggtcgaattc gcggcgtcta
    18781 ccgccccgaa ggtcacagtg atggcgggtg cgcgtcgcgg ggtgccgcga gatcggtggc
    18841 ggggctccgc ttggtccccg aaggccaccc tcggggacac tagcgccact ttcccggccc
    18901 tcgcaggcgt ccggacacgg ctgcgcacgc cccgaaagcc accctcgggg cgctagacga
    18961 cacaaatcca cccctcgcac gcccaaccat cgcgacgcgc atgccccgaa ggtgaccttc
    19021 ggggcgctag atgccctgaa agccaccttc ggggcaccag gaagatcccc gccgaggcag
    19081 cagaagcccc ctaccagagc gaagttcgcg gcaccggagt cgctgaaggc caccccatga
    19141 catctatagg agcatccttc ggggacgcgc gcaggtggcg gcagcccgcc gcgagagccg
    19201 agatcctgac acagaccgcc ccaagaggag cctccggcga catacacgac ccgaccctca
    19261 gtaggagcat ccttcggggc atggtgatcc ggtcggccgc ctcgacgggc accgcgccgg
    19321 gtgaccacga tcggtgaact ccggtacccg gtcgcaccaa cgacgtcaca ctacggcggg
    19381 tagtcgacgc caacaactgt ccattgtgca ccagtcgagc actccgctga aatccgagtt
    19441 atattcagga aagttaaaca acggtcaaga catatcagac cggttctgtc actgtaagta
    19501 gcgggtgcgg tgtcgagttc catgatcgtc gcggtacttt tccgcacgtc cccgcgagcc
    19561 tcaacgacgt ggccgctcgg cgggaccggg catccggttc ccgctgtctt cccaccccca
    19621 aacggtcagc cgcgcccatg cgcgcgtcgc tggcgccttg gagagatctg cttgaaagac
    19681 accacaccgc cggccttcgc ggcaccgttc gtgcccgccc agccgacggc acggagcctg
    19741 tcccgcacgc accgcaccac cgcgttctcg cagcggttgc tcgtgcactg ggaccccgag
    19801 accggctggg cgcacctggc cgtcgcggaa ccgggcggcg cgaaccctcg gttcgccgga
    19861 ttccaccgct ttcccagcgg tgacaccgat tcggtgctgg ccgcgctcac cgaagcgggc
    19921 tgggacgctg gacagcccac cgaactcgaa gacggcatgc tgggcgtccg ggcccgcccc
    19981 gggcgcgaac gggagggccg atgagattcg acgacctcca cctcaccggg atcggctgcc
    20041 acctcggatc gctgaccccg gtctcgggcc ccgtgaccgc gggaacgtac acaccggaag
    20101 aagccgcgaa aacgggccag ctctcgacct cggtcgccga ccggcacggc cccgatctcg
    20161 cggtgagcgc ggcgcgggaa gcgctgcgcc acgccgacgc cgtctccggc gagaccgtcc
    20221 gcccgtcgct ttccctgcac gccgggatct actacgccgg gatcgacttc tggcacgccg
    20281 cctcctacgt gcgcgaccag ctcggcatcg ggccgtgggc ggggctggca ctggaaatcg
    20341 gcgcgatgag caacagcatg gtcgcgggcc tcgacctcgc cgccagcgtg ctcagcggcc
    20401 gccccgacca cgaagacgtg ctcctcaccg cgggcgaccg cttcggcgat cccggttttc
    20461 cgcactggag caccgatatc ggcatcgttt acggcgacgc gggcagcgcg atcgtggtat
    20521 cgcggcggcc ggggttcgcg cggctgctgt ccgtggcgtc cttttccgac ccgtcgctgg
    20581 aaggcctgca acgcggcgcc gaaccgttcc gatcggtcag ttccgccgcg cgcaccccga
    20641 tcgacatccg gctccgcaag cgccaatggc tcgaagaccg gggtaccgac tacgtgcaca
    20701 cgcgcaacag cgacgcggtg accaccgtgg tgaagacggc gctgaccgac gcgggcctcg
    20761 atctccccga cctggccaag atctgcgccc cgcactacgg gcgccacctg gtgcgcagcc
    20821 agatcctgcg cccgctcggc atcgccgagg agcagaccat gaccgggctc ggcctccggc
    20881 tcgggcatct cggtgccagc gaccagatcg tcgcgctgca ccacctgatg cgcaccggcg
    20941 aggcgcgccg aggcgatcac gtgctcctgc tcggggtggg ggtcgggatg acctggaccg
    21001 ccgccgtcct gcgcatcgaa cgggagatcc cgccgccggg cggaatcggg cgctgacggc
    21061 gtcccgcccg gcaggacgtg ccacgacgcg cgtcctgccg ggcggaggtc agtcccgttc
    21121 cgccgcgagc gcggcgctgg ccgcgcgcca gcgggcttcc catgcccgct catcgccgcc
    21181 gcaggcacgg acgaacgccg tcgtcacggc cagggtcggc agcttcttcc cgcccgtggc
    21241 ctcggacaac gtgcccgcgg cgtagtgcgc gcgccgggcg agctcgcgga acgtcggcgt
    21301 cccggcgtcc acccgcagcc gccgcagctc cgccgcgaac cgcgtcaccg caccgccatc
    21361 ctcgtccagc ggacgttccc ggcgccccat cgcgaacccc ctcgatccgc gccgattgtt
    21421 cggcagtgcc ccggccggcg tccagcgcgg gcgcccgaac aacccgaacg cactacacca
    21481 tcggccgtac gccgtaaggc atcggcaaca tcccatccgg tggaagaccg cgggacccgg
    21541 ggatatcgtg gtgtcaagag cccatccgag gtctgtcgca aaggagccgc ggtatgtcca
    21601 ccccgtccga aaagccagtc gagaaggcga tcctcgccgg tggctgcttc tgggggatgc
    21661 aggacctgtt ccgccgtcag ccgggagtgg tctcgacgcg cgtcggctac acgggtggca
    21721 ccgtggcgaa cgccacctac cggaaccacg aaggccacgc cgaggccatc gaagtgcttt
    21781 acgacccggc ggagacggac ttccgggcgc tgctggagtt cttcttccag gtgcacgacc
    21841 cgagcacgaa ggaccgccag ggcaacgaca tcggcaccag ctaccggtcg gcgatcttct
    21901 acaccaccga cgagcagaag aaagtcgccg aagagaccat cgccgaggtc gacgcctccg
    21961 gcctgtggcc gggcaaggtg gtcaccgagg tcgtccccgc gggcgacttc tgggaggcgg
    22021 agccggagca ccaggactac ctgctgcgga tcccgcacgg ctacacctgc cacttccccc
    22081 ggccggactg gaaactgccc gcccgccact gaccgcggcg attccggccg gatttcccgt
    22141 attccgacaa cgatctcgcg caccacggtc gggtgacgcg gagagccgga accgctgcca
    22201 cgccctaatc tcgcgtcgac ttcgacgggg agggtgcgcc atggcagagg gcaaatcgac
    22261 cgcgcggcca cgcgaactgg gcaggggcgc gcgcaacctg gtcgtcgccg cgatcatgct
    22321 cggcatgctg ctgtccgcgc tcgaccagac gatcgtggcc acggcgctgc cgacgatcgt
    22381 cggcgatctc ggcggcggtt cgcacctgtc ctgggtggtc accgcgtacc tgctcgccga
    22441 gaccatcatg accgcgctga tcgggaagtt cggcgatctg ttcggccgca agaaggcgtt
    22501 catcgcgagc gtggcgctgt tcctggtcgg ctcgttcttc gcgggatggg ccgaccagat
    22561 gggcaccctc atcgcgttcc gcgcggtgca gggcctcggc ggcggcgggc tgatggtcac
    22621 cgccgccgcg gtgatcgccg acgtggtacc cctgcgggaa cgcggcaagt accagggttt
    22681 catcggcgcg gtgttcggca tctcgaccgt ggtcgggccg ttgctcggcg ggctgttcgt
    22741 cgaccacctg agctggcgct gggcgttcta cgtcaacatc ccgctcggga ttctcgtgct
    22801 cgtgatcgcc gcgatcgcgc tcccccgggt cgtttcgacg gcgaaacccc gtatcgacta
    22861 cctcggcatc atcctgatcg cgctggccgc cagcgggctc accctggtca ccagctgggg
    22921 cgggaccgag tacccgtggg gttcgccgac gatcctgctg atggccgccg cctcggtcgt
    22981 gctgctgatc gcgttcgtac tggtggaaca gcgcgccgcg gagccgatgc tgccgatgcg
    23041 gctgttccgc gggcgggtgt tcagcgtgtc gggcatcctc agcttcctgg tcgggttcgc
    23101 catgctcggc gggatcacct acctgccgac ctacctgcag tacgtccgcg gcgagaccgc
    23161 gacgcagtcg gggctgtgga tgctgccgct cgtggcggga ctgatggccg ccgcactggc
    23221 caccggcacc gtgatcagca ggaccggccg ctaccggctc ttcccgatcg ccggctcggt
    23281 gctgatggtg gcggggctcc tgctgatgtc gctgctcgac gccgatacca gctactggct
    23341 gatgagcctc tacatgatcg tgctcggcgc cggggtcggg ctcatcatgc aggtgccggt
    23401 gatcgtcgtg cagagcaccg cggactacgc ggacctcggc gtcgccacct cgggcgtgag
    23461 cttcctgcgc acgctgggga gttcgttcgg ggtggcgctg ttcggcacga tctactcggg
    23521 caacctgccg gacaagctcg ccgccgcgct cgcccggaac ccgctaccgc ccggggtcga
    23581 tccgcgcgtg gcgcagagcc cgcaggcatt gcacgcgctg cccgcgtcgc tgcgcacccc
    23641 gatcatcggg gcctatgtgg acactctcca cctgatgttc ctatacgccg cgcccgtcgg
    23701 tgtgctggcg ctcgtggtcg cgctgttcct gaaggaggtt ccgctacggg acacttcgcg
    23761 cgcggcggcc tcggggaaca gcggggtcgg cgaaagcttc gcggtgcccg cgtcgagcga
    23821 ttcggagcag gagctggaaa agctcatcgc gaccatgatg ggacggctca aatccgaccc
    23881 tggcaacgaa atcctcgcca ggaccgggct gacgatcacg atcgcgcagg cgtggctgct
    23941 ccagcacgtc taccgcactt cggtggacga cggcgacgcg accatgcagg agatcgccga
    24001 actgaccgac gtgccggccg ggatcttcga accgaccgcg cagcagctcg tcggcctcgg
    24061 cctcctcgtc gaaaccgatg gccactaccg gttcacgacc gaaggcagcg aggtgttcac
    24121 ccagctcgtc gcgggctggc gcgactggct gctcgatcag ctcgcggact ggcgggaacc
    24181 gcggcagcgg gaattcaccg aagccgtcga cgcgatggcg aggcggatca ccgacaccgg
    24241 ccgttccctg ggcgtcggcc gccacgcgat gctgtgatca atgctcgaag ttgattcgtt
    24301 ctctgcgctt tcaagcacgt ccagtcggat tggctcttga cccggcgcgc gaccgccgca
    24361 taggttcaga ccactgtcac cgaccggacg gggtgccatg aggacgcgtc tgctagcact
    24421 gacctgcgcg gcggtgaccg cgctcggcac cgtcacggtc accggcgccg cggccgggac
    24481 cgatgccgcg ggcgccttcg acacggcggc cgcgcgggcg agcctgcacc gcgtcctgcc
    24541 cggcgccgac cgccagttcc gccttcgcgc gcttcccccg caggaaacgg gcgaccactt
    24601 cgaaatctcc ggtcacgccg gtgcgatcac cgtcgccgcc acctcccccg cgacgctgct
    24661 cgccggggct ggctggtacc tggagcacgt ggccggtgtc gacatctcgt tgccgggaca
    24721 aagcgtttcg cggttgcccg gcgtgctgcc cgcgccgccg ggcgtgatcc ggcaggcggc
    24781 ctcggtggcg aaccggttcg cgctcaacga caccgacgag ggctactccg gtccctatcg
    24841 cgatttcgcc tcgtacgaac gggaaatcga cgtgctcgcg ttgcacggcg tcaacgaggt
    24901 gttcgtggaa acgggcacgg acgcggtcta ctacgaagcg ctgcgctcgt tcggctacac
    24961 gcgctcggag ctgctgtcct ggattcccgg ccccgcgcac cagccgtggt ggctgctgca
    25021 gaacatgtcc tcgttcggcg gcccggtccc cgagcgcctc gtcctcgacc gcgccgcgct
    25081 cggcaagcgg ctcgtcgacc ggctccacga cctcggcatg acaccggtgc tgccgggtta
    25141 cttcggcacc gtgccaccgc gtttcaccga gaagaatcca tcggcgcggg tggtgccgca
    25201 gggcgactgg ggcgggttca cccggccgga ctggctcgat ccgcgcaatc cggtgttcgc
    25261 caggctcgcc gcggagttct accgctggca ggcacggctg gtcggcaccg gctcgatggt
    25321 gaagatggac ctgctgcacg aaggcggcca ggccggtgac gtaccggtcg ccgacgccgc
    25381 gcgggccgtg ttcgccgcga tggaccgggc ccgtcccggc gcgacctggg tgctgctcgg
    25441 ctggcagagc aacccgaagc cggagatcat cgacgcggta cccgaccgga aacgactgtt
    25501 catcgtggac ggactgtccg atcgctacaa cgacctcgac cgcgaaaaga cctggaaggg
    25561 cactccctac gcgttcggca cgatcccgaa cttcggcggg cacaccacga tcggcgccaa
    25621 caccggcgtg tggtcaagcc ggttcgacca gtggcggtcc aaaccggaca gtgcgctggc
    25681 cgggatcgcc tacctgccgg agggcaccgg gaccgatccc gtcgcgttcg agatgttcac
    25741 cgatctcgcg tggcacgacg ggccgctgga ccaggcggcg tggttcgccg ggtacgcggc
    25801 gcggcggtac ggctgcgccg acccgcacgc caccgcggcg tgggacgcgt tacggcgcgg
    25861 gccgtacagc atgccgtcgg gcaagtggag cgaagcgcag gacgggttgt tcaccgcgcg
    25921 gcccagcctg accgcgacca aagccgccgc gtactcgccg gaggagatgc ggtacgaccc
    25981 ggccacggtg aagaccgcgc tcgcggaact gctcgccgtg gcaccgtcct gccgcaccac
    26041 cgacgcctac cggtacgacc tggtgaacac cgcgcggcag gtgctcgcca acgcgagccg
    26101 ggatctgctg ccccggctga aatccgccta cgaccgcaag gacctgcccg ggttccgcgc
    26161 gctggccggg cagtggcgcg gcgatctcgc cctgctggac tccttgctcg gcagcgaccc
    26221 gcggttcctg atcggaccgt ggctcgacgc cgcgaagtcc agcgcgcgcg gagacgcgca
    26281 acgcgcccgg ttcgagtacg acgcgcgctc gatcatcacc acctggggcg accgcgccgc
    26341 gagcgacgac ggcaacctgc acgactacgc caaccgcgag ctttccggtc tggtgcgcga
    26401 cttctacgcg atgcgctgga acacctacct cgactcgctg gacaaggcac tcgtcaccgg
    26461 cggccaaccc gcgccgatcg actggtacgc actggaagac ggctggaacc gggcgcggcg
    26521 gtcgtacccg gtcaccgcca ccggcgatcc ccaccagctc gccacgcagg tggcgaacct
    26581 cccgtcctag cgcgccttct agcggcccga tgaaacgagt cctatcggga cgggtcctaa
    26641 cgggacagtt cggcttcggc gcggatgtcg agcaggagct tgtcgatgtc ggcctgggtg
    26701 gtcgtcgggt tgagcagggt gagcttgagg tacgtggcgg gccgccctga ccggtccggc
    26761 atcgtggtgc gcccgaccac ggccgtcccc gacgccagca acgcgcgccg cagccgtgcg
    26821 ttggcctggt cgggatccgt gcccgcgggc gggaggaagc ggaacaccac ggtgctcagc
    26881 gtcggttcgg cgcgcagttc cagccccggg tcggcgccga tctccgccgc cgcgtaccgc
    26941 gcgaggtcgt ggcagcggtc caccagcgcg ccgaggccgc gcctgccgaa cgcccgcaac
    27001 gtcaccgcga tcttggcggc gtcggcgcgc cgggtggtcc gcagggacag gccgagcctg
    27061 ctgcggtacc cggccgcctc gtcgtcggcg gggttgaggt aggcgaccgt gcggtcgagc
    27121 gtgcggaacc cggcgcggtc gcggctgagg aacaccccgg ccgcgaccgg ctgccagccc
    27181 agcttgtgca ggtccagccc gaccgaatcg gaccggccga tcccggcgag cagcggcgcg
    27241 agccggtcgg agaacagtgc gccgccaccg taggccgcgt cgacgtggaa ccagacccgg
    27301 tgcgcgtagg tcagttcggc gatcgccccc agtggatcga tcgcgccgag gtcggtggtg
    27361 cccgcggtgg ccaccacggc gagcgggacc tcgccgcgct cgcgcacccg catcagttcg
    27421 acgcacagcg cgtccggacg catccggtcg gcttcgtcga ccgcgaccgg cagcaccgcg
    27481 tcctcaccca gcccgagcag cccggccgat cgcgcgaccg aaaagtgcgc gaccgaagag
    27541 cacaggatgc gcagcttgcc ggtcagctcg gccggaatcc cggtgcggga gacctccgca
    27601 ccggtgatgg cacgcacgat ccggtcacgg gccagcagca accccatcag gttcgactcg
    27661 gtgccgcccg tggtcacggc cccgccagcg gttccggcgt cgtacccggt gagcccggcc
    27721 agtgccgcga ccaggcggtc ttccagcgcg ctcgcggcgg gtgcctggtc ccacgagtcc
    27781 agcgaagggt tcagcgcgga gaccgcggtg tcggcggcga ccgcgaccgc gagcggcggg
    27841 cagtgcaggt gcgcggcgca cgccggatcg gccggatcgg ccgccccttc ggccagcctc
    27901 gtgacgatct cggtcagcgc gtggtccggc cctgccccgg tttccgggag cagcgcgccg
    27961 aatccggccg cccacgcccg tgccagcgcg tccggttccc cggccgggat cggcccgccc
    28021 ctggcccgca caccctcgcc gacggcgtcg agcgtggtct tcaagtagcc tgccagcgcg
    28081 gcccttcccg tagtcgtgcc cgcgaagatg ggatccattt ccacctacct cccgctcgag
    28141 acgccgtgat cgacaccgac gctacgggag cgcggggcgc ggccgcgaaa aggaagtgtc
    28201 aaggacacgc gcgcgggcga aaaggcttcg acaacaacga aatcaccgcc gcccggcatg
    28261 cgccgtcatg accggatcga cgccgattcg cccgctgtgt ccgatgtgga cggttctggt
    28321 gcgtcgtcgc cggaacgcgg gccgcggagg atgccccatc ccacgagtgc cgccgacgcc
    28381 agggtgagcg cgagaccggc gtaggtgatc gcctcgcgga acccggcggc ctgccgcgcg
    28441 ctccacgcgg ccgtggtcag cgcgccgggg acgaccaccg ccaggatggt gccgctcagc
    28501 gcgatgccga ccccggtggt gacctcgctg gcggtgtcga tgagcgcggc tccgatggtg
    28561 gtgcggttcg cgggcaaacc gcgcatcacg ttggtgcccg ccaccacgcc gaccacgcgc
    28621 atgcccgccg cgacgagcgc gagcgcgacg gcaatccagg cgtagccgaa cctgccgaac
    28681 gcggtgtaga cggcgagccc gcacacgacc gcgcccgcgc tgagccaggc ggccttgacc
    28741 gggctgacgc ggtcgagcag cgggccgatc acggcgccgc ccgcgatcag gacgacgacc
    28801 tgcggcagca tcccgagtgc cgcttgcgcg ggcgcccagc ccagcccgag ctgcaggtgc
    28861 agtgtcgcga ggtagctgag cccggcggtg gccagtcccg ccgcggcctt gagcgcgagg
    28921 ccactggaca cgagcgggcg ggcgatgagc ttcaggtcga gcagcgggtg ccggattgcc
    28981 ttctcccgca agacgaaacc ggttcccgcg gcgaccgcgg ccgcggtcgc cgcccacggc
    29041 agagccgaag cggcgcccgc ttcgacgaag aacgtgggcg cgagcagtgc gaagacgatc
    29101 gtcgcggtgc ccagtacggc gccggccacg tcgaccggat cgcggtgcag gtcggcgggg
    29161 tcgtcggcgg gaatgcccgc gcggatgccg aggaacgcga gcgcggcgac cggcgcgttc
    29221 gccagcagca gcacctgcca cggcgcgacc gcgagcacga gcccgcccgc cgtgggaccg
    29281 acggcgaggc cgaccatgcc caccgtcgag atcagcgtga tcgcgcgcgt gcgcagccgg
    29341 tcgtcgtcga acaggcggaa cgcgagggcc atcgagcccg gtgtggtcat cgcggccgcg
    29401 acacccatga gcgcccggac tgcgatgagc tgccacgcgg ccgtgacgaa caccgtcgcg
    29461 aagctcgcgg cgccgagcag cacgagcccg aagagcatga ccttgcgcct gcccgcccgg
    29521 tcggccagcg caccgagcac cagcatcagc ccgccgaaca cgacggagta caccccggtc
    29581 acccattgca gggtggtcgt ggaggtggcg agctcgcggc cgatggtcgg cagcgcgacg
    29641 ttgaggatcg aattgtcgag catctcgaac aggaacacgg ccgagagccc ggcgagcgcc
    29701 tgccaggccg cgccgagcga ccgaggagca cgggatgtgt ggacggggga acgcatggca
    29761 ccactccttc gcgatgaagg agtgacggat cgttcgatac cgcgtgtgcg cgcgccctgc
    29821 cgggcgcgtt tctaccccga tgggccgatg ctacaacatc ggttccacgt caccagcgtt
    29881 ctgtgtgcag gacctcgtcg agcgccatcc tggaccgcca gcccgcgcgt tccaggtccg
    29941 gcacctcggc cagccgctcg acgggaccga cgcacagcca cgccaccggc cgcacgtgcg
    30001 cggggatgcc gagcagctcg cgcacgaact cctcgcggta gaagctgacc cagccgacgc
    30061 cgaggccctc cgcggtggcg gtgagccaca ggttctggat cgccaggcac accgagtaca
    30121 gcccggcgtc ggcgatcgcg tgcctgccga gcaccgccgg tgcgccgcgg gcgggatcgt
    30181 aagtgaccac aatggacagt ggagcatcga gaacgccctc gatcttgatg ccgtcgaaca
    30241 ccttcgccgc ggccccgctc agcgagcccg cgaaccgggc gcgttcggcc tgcacgtgac
    30301 cgtggaaggc acgccgcgtc ccgccgtcct cgacgaggac gaagtcccac ggctggctca
    30361 gcccgacgct cggcgcctgg tgcgccgcgg tgagcacccg ccgcagcacc tcgggatcca
    30421 ccggctcgcc ggtgaactcg gaccggacgt cgcggcgctt gcccacgacc tcgtacagga
    30481 actccgcagc cgtcatgccg gggattgtcc cgtgcgcccg gcgcggaccc ggaggtggtg
    30541 caccacgacg gcgagcgttg cggcgacgaa caccacctgc atcgccgtac ggggcacgag
    30601 ctggtcctcg aacgggatcg cccgcccgtc cagtgccttg acgacgttcg ccgggaacat
    30661 gaccacgagc agcgcgccga ggcagcccgc cgcccacggc gcggtgcgcc gccacagcag
    30721 tcccgccgcc ccggccagct ccagcagccc ggtcagggtg accaggaaac cgggcgcggg
    30781 cagagccgcc gggaccatgc tgatcagttc ttcgcgcatg ccaacgaaat gcgcgacccc
    30841 ggtggccacg aacatcgcgg cgaggccgcc gcgcaccgcg acgggccacg gtctcagcgc
    30901 gcggacaccc gccgcgcccg caccgagcag gacgagggtg accaccacga gaatcacgag
    30961 cggagccatc ggaaaatccc ttcaccagta aatctaggca gtgacaagat tgggtggccg
    31021 agtgcatctt gtcaatgact agattctggt tagagtgggg ccatgccgta ccaccacgga
    31081 gacctccggc gcgctgtgct cgacgccgcg gtcgcggcca tcaccgagca cggcgcggcc
    31141 gggatcagcc tgcgcgacct ggcgcgccgg gccggggtgt cccatgccgc gccggtgcac
    31201 cacttcggag acaaggcggg tctgctcacc gcgctcgccg ccgagggcta cgaaatgctg
    31261 gccgcggcgc tcgccgaaac gcgggaacgc accggggact tcgtcgaagc gggggtcacc
    31321 tacgtccgtt tcgcgctcgg ccaccacgcg cacttcgcgg tcatgttctc ccccggcctc
    31381 ttccgcgccg acgatcccgc ggtcgtctcg gcgcaggaac ggacctacga actgctcgtc
    31441 agcggggcac gggcggtccg aggcgaaccg ggggtcgccg aaatcgccgc gtggtcgctc
    31501 gtgcacgggt tcgcgacgct gtggctgacc ggcgcgctgc cgcccggggc cgccgaggac
    31561 cccgagcggt cagcgcgcgc gatcgccagg atcctcaccg gatcctgagc gggctcacct
    31621 cagcagaagt tcgcgagccg cacgaaaccg ccgaggttct cgtcatcggt gccgagcaca
    31681 cccgacgcgg ccccgcaggc gagcgcctcg atcttgtgcc cctcgtactt cgcgaccggg
    31741 gtggggtcct tgaccgtgtc gagcgcgacg cggtcaccgt cgagcttcac ggtgccgccg
    31801 cggtagagcg ccgaatcgaa cgggccgtcg tccccgttgt ccgaggccga ggaaatcacc
    31861 agtgcgccgt cggccagcac cttcacgtcc gacacgtgcc gcaccttctt ctcggggtag
    31921 ggcgcggtga acttcgccga caccggggcc gagaacttgc cttgcccgag atcgacctcc
    31981 gcggccgaaa ccacacccgg ttccgcgtcc ttgccgcggt cggcccacac cgcgacggtc
    32041 ttcccaccga tcgcgctcag cgcgaaccct tcgtagttgg ccttgtcgtc cagatccggc
    32101 aacgggaacg agcgcacgac cgtcgcttta gcactgtcca cagtgatcag atacgcggta
    32161 ccggaactgg ccagcgccac gaactcgccc gccttccccg gcacggcgtc gatcgcttcg
    32221 agatcggtgg gcagctcacc ggaccacgcc aggtcggtcg aggtcgcggc accggaggcg
    32281 ggcacgcgca cgagcgcgac ccggttctgg ccgtcctcct tgttgtcccg cacgatcaca
    32341 gcgtcggtcc cggccgcggt cgagccggtc accgccatcc cgctgacacc accggtgatg
    32401 ccactgccga cctgctgcca ttcgggggcg gcctgcgccg ccgggctcgc caccagtcca
    32461 cacaggccgc acgcggcggc aagggcaagg tacgccttgg tcacggacac tccattcggg
    32521 tcgaaacggc gttcgcgggc gggcgactgg cggccggcgc cccgatcccg cgtgccgatg
    32581 atcatttcga gccgaacggt acccggcggg ttcggaatcg ggaacctgct aacgggggga
    32641 agcggtaatc ggtgaactcc attcgagatg gtggccgtac agccacgcgc gctcggtctc
    32701 ccgccgccgc gcctcctccg aggtggtccg gccagcgccc tggctcccgc tgaccgcgac
    32761 cagccgttcc acccgcgccc ggcggatctc ctcgtaccgc cggaacgcgt ccacgcgcgc
    32821 cggctcgtcg cgaaggcaca tcgccagcac gacgctgtct tcgagcgcca tcgacgcacc
    32881 ctgccccgcg gccggtgacg ccgcgtgcgc cgcgtcgccg acgagcaccg cggcaccgga
    32941 cgaccagcgc ggcgtggtcg gtacgtcgta ggcgttgccg ccgaagacgt cctcacccgt
    33001 cgcgcggatg atctcggcgg cggggttccg gtcgccgtcg aaccgcgcgg ccgcgcgctc
    33061 ccgccaccgc gcgggcgtcg tctcccgcgt accggtcagt tcggcacccg gcagccgcgc
    33121 gaaccaccac gtggtgccgc cgggatcggt cgtgtacccg aagaacgcgg tggcgccctg
    33181 gatcatccgg taggtggcgg gcggggccgg atgcggcgcg gcgggcgcgt acccgtagac
    33241 gacggcgagc ccggcgtacc tcggctccgg ggcatccggg tcgatcaggc gccgtgcggc
    33301 ggagtggatg ccgtcggcgc cgaccacgaa atcggcttcg gcgcgcgtgc cgtcggtgaa
    33361 gcacacgccg ccgtcgaagg aagcgaggcg tttgccgtgc gcgatcgttc cgccgcggcg
    33421 gacgaactcg tcgtgcagca cgcggtggag atcggcgcgc cggatcgtgc gcggggccag
    33481 caggtcctcg cgggcgctgc cgatgggctg cacggggagc gcgccgccgt cgtaggagaa
    33541 ctcgacctcg ttggtggcga acgacttggc ggcgacgacc tcgtgcgcgt cgatcgcggc
    33601 gagcgcgtcc atcccgttgt gcatgagggt gaggaacgcg cccgcgtcgt cggcaccggt
    33661 cgggtacgcc tcgtagacgg tgctgccgat ccccgccttg aggagcgcga tggcggtcgc
    33721 ggtaccggcg atcccgcccc cgatgactgc cgcggtcgtc atgcgcgcct ccccttttcg
    33781 gctcaaccta gccgtttccg ctcgaagcgg acaccggcag gcgggtgcgt cacgccagtt
    33841 cgtccaggtg cgcgagcgcc tcgcccaccg agcccgccgg gtcggtgacc gggaactgga
    33901 ccgccctgat cacctgcccc ggatcgacca gcagcgtcag ccgcttcagc cggtcgaccc
    33961 cgccggcgcg gaacgtgggc aggcgcagcg ccgcggtgag cgcgaggtcg gagtcggaca
    34021 gcagcgcgaa cgggagcgcg gcgtgctcgg agaaggctcg cagctggtcg gggcgttgcg
    34081 tgctgacccc gcgcacggtg actcccctgc cgtcgaactc ggcgaagcgg tcgcggtagg
    34141 tcgtcgactc gagggtgcag cccggcgcgc cggggatgtc gccccagccc ggtggcagcg
    34201 ggttcccccg tggggcgaac gcgccgggaa aggcgtagag caccgaccac ccctggccgg
    34261 tgggcgtcat cggctccccc gtgtcggata tcaggagcgt cgcgggcacc cgggtgccca
    34321 ccagcgcccg cacccgcctc gcctcggccg aggtcggtga gctcgtcgcg gtgagcgagc
    34381 cgtccccggc gacgaaccgc gtgccccagt cctgcaacgc gacgagcacc ggcagcaggc
    34441 cgcggccggt gtcggtcagg cggtattcgt accgcggcgg gcgctccgag tagtgcacct
    34501 tctcgaccac gccgtcggcc accagcgcct tgagccgttc ggtgagcgtc ttcctgctga
    34561 tgtcgagttc ctgctgcagg gcatcgaacc gggtgaggcc accggcgatg tcgcgcacga
    34621 cgagcagcgt ccaccagtcg ccgacgacac cgagcgcctg ggcgatcgcg cagtcggcgt
    34681 cggcgagttc gcggtacttc atggccgctc cttccgtccg cgaccgcacc accctaaggt
    34741 aagttccggt tttgaactca cctcagggtg gttggtacct ggcggccact ggacatgaat
    34801 gtccactgtg gacggcgcac cgcgattcga ccgcccgccg tcacccgcgg gctaaccgct
    34861 ctccgcgacc ctgtcgagcc actcggccag cagtgcgccg aacagcgcgg gctgttcgag
    34921 ctgcaggttg tggcccgccc tgtcgagcac cgcgaacgac gccctcggat agtggcctag
    34981 cagcgcgtac tggtcctcgt aaccggtgat cgagtcctgc cgtccggtca gcacgaggac
    35041 cgggcgttcg taggcggggc cgctctccgg cgggaccgag agcgtgtagt tctcccgcac
    35101 ccgcgccagc gtcgtctcgt ctgcgagcgc gagccccggc gccacctccg cccggtacct
    35161 ggccaggatc tccggtgacc gcacgaccgc gatctcggtg aaatcggcgg cctccgccgc
    35221 gtccatcgag gcgataagcg cgggatccga cctgagcacg gtgtgcggcg ggagggtgcg
    35281 ccgcgcgtgc tcgggttcag tgccgatcgg gcagatcagc gccatccccc gcacctggcc
    35341 cggccgttcg cgcaccagcg cgcgggcgag ataaccgccg taggactcgc cgacgagcag
    35401 gaacggctcc gcgccgaggt gctcgtcggc gaaggacgac accgcggcca gcaggtcgtc
    35461 cgaaccgcgt gccgaaccgc ccggcgactt ccccatcccc ggcaggtccg ggtagaggcg
    35521 ccggtagccg ggccgctcgg cgaacaccgg ttcgaggcaa ccggacatca tccggtgatc
    35581 cggcgtccag ccgtgcagcg ccagcaccgg gacgccggag ccgaactctt cgtggaaaac
    35641 ctgagctgtc atgtcttccc ccttgatccg cgatcaggtt tagcagaggg ggccgacaga
    35701 acccggttca gccgtcgaag gtttcgggat cgggaccggt gcggcggccg cggtccagcc
    35761 cgccgagtgc ccgcatgtcc tcatcggaca gtgcgaagcc gaacacgtcg atgttctcgc
    35821 ggatccgctc cggtgaagag gacttcggga acacgatgtg gccgagcgcg aggtgccagc
    35881 ggagcacgac ctgcgccgcc gtcctgccgt gcgcggcggc gatgcgggtg accacctcgt
    35941 cgccgaggac ctcgccctgc gcgatcgggc tccacgcctc ggtcgcgatc ccgtgctcct
    36001 cgtggtaccg gcgcagctcc gcctgctgca ggtacgggtg cagctcgatc tggttgaccg
    36061 agggcaccgc gccggtctcc ccggcgagcc ggtcgaggtg cgccggggag aagttcgaca
    36121 cgccgatcgc gcgcgccttc cccgccttca ggatctcgtc gaacgcctgc cacgtcttga
    36181 cgtagcgatc cttggcgggc aacggccagt ggatcaggta caggtcgacg tagtccgtgc
    36241 cgagccgccg caagctgcct tcgagcgcgg tgatggcgtt gtcgtggccc tgggcgtcgt
    36301 tggcgagctt ggtcgtcacg aacacctcct cgcggggcac gcccgatttc ttgataccgg
    36361 ccccgacgcc ctgttcgttg cggtacatct gcgcggtgtc gatgtgccgg taacccgcgt
    36421 cgagggcgag cgcgaccgcg tcggccgtcc ggtccggctc gatcccgaac acgccgaaac
    36481 cgaactgcgg gatcggcacc ccgccggtca accggatgct gggcaccgtc gtgggggagg
    36541 tcatgccctt gcctacccat cccggcgcgc gcgaaaccgg catgtcggag atccgggcgt
    36601 aggtccccga ccggcccggc gctaaggtga aacccggttg acgccaacag ccatccagtc
    36661 cgcgcggggc aacgcgcggg ctttcttcat ccgtcccggc acgccgggca gcggactcca
    36721 cagaggaaag gctggatgtc ctgtcgaacg cactgcgagc gggggttccg gtgatgccgg
    36781 acgaagccgc gcccctgcac gtcctcctcg tcgaagacga cgacggcgac gccctgctcg
    36841 tcgaagagtt cctcgccgac agcgcggccc cgatcacgct ggaccgggtc gccaccatgg
    36901 ccgacgccgt cggcgcgccc gtcacggccg actgcgtgct gctcgacctc aacctgccgg
    36961 acgcggtcgg catcgccggg gtgacgaggg tgcgcaggca cgcccccggt accgcggtgg
    37021 tcgtgctgac cgggcacaac gacgaggaga ccgggatcgc cgcggtcgcc gccggcgcgc
    37081 aggactacct ggtcaaggac caggtcgacg ggctgctgct gatcaaggcg ctgcggtacg
    37141 cacgcgagcg caaacgggcc gagcaggtcg agcagcagct gctcgaacag cagttgctgg
    37201 cgaacgagaa ctcgcggctc gagcgcgggc tgctgccgac gccgctgctc gcggactcgc
    37261 acctggccct gaccacccgg taccgccccg gccgcgacgg gtcgctgctc ggcggcgact
    37321 tctacgacgc cgtcgaactc gccgacggca ccgtcaacgt gatcatcggg gacgtgtgcg
    37381 ggcacgggcc ggacgaggcc gcgctcggcg tggcgctgcg gatcgcgtgg cggtcgctgg
    37441 tactggccgg gctcgcctcc ggtgaggtgc tgaccatggt cgaacgcgtg ctgcggcacg
    37501 agcggatccg ctcggtgttc gccaccgtgt gcatggtcac cgtggcggcg gaccgcggct
    37561 cgctgcggat gagcctcgcc gggcacccgc cgccgctgct ggtcaccggc gacggcggtg
    37621 agctgctgcc gaacgaccgg ctcggcgttc cgctcggggt ggtcgacgac gcgcggtggg
    37681 agccgctcga agtgccgctg ccaccggagt ggtcgctgct gctctacacc gacggcgttt
    37741 tcgaaggccg cgtcgaagaa gggatcgaac ggctcggcca cgaggaaatg gcgaaactgg
    37801 tgctcgggat actcggccgg gagcccgagc acggcaaggt gctcgacgag ctgatcgcga
    37861 ccgtggagcg cctcaaccgc ggcccgctcg acgacgacgt cgcgctggcc atgctgacgc
    37921 accggagcgg ccgatgaccg acgaccacgt ccggcgctgg tcgctgcggc ggtgggcgac
    37981 gctgctcggg ttcgccgagg ccgtgctcct ggtggccgcg ctcgtgggcg gcggtgtcgc
    38041 gctcaagacc ttcgacgacg cgcgcacccg cctcgtcgac cagaccggtc ccgagctgct
    38101 gcaggccacc acgctgtcca ccggcctgct gaaccaggag acgggcctgc gcggctacct
    38161 gctcaccggg cagggcgatt tcctgacccc gtacgaacag ggcaagcggc aggaggcggt
    38221 cgcggtcgcg gagctgcggc gcctcggcgc ggtaccgggt accgaagccg gcgcggacct
    38281 cgacgccgtc cagcgggccg ccgaggcgtg gcgcgccgaa gcgcgtcccg acgcgccgcc
    38341 accgcaggcc gaccgcggga aggggctctt cgacgcggtg cggaccgcgc tggacaccca
    38401 gcagcggcac ctcgccgcgg ccagggacgc cgccagggaa agcctcgccg acgcgaacac
    38461 gatcctcacc accatgctcg tggtcatcgc ggcgctggtg ctgctgttgt tcctgctcgt
    38521 ctacctcggg ttccggcgca ccatcacccg gccggtcatc cggctggccg agcaggtcag
    38581 ggcggtgtcg gcggacgacc tgcgcgggga ggtgcgcggc gacgggccgc gcgaggtccg
    38641 gcagctcgcc gaggacgtgg aggcgatgcg gcggcgcatc ctcggcgagg tcgcggaact
    38701 ggagcgcgcg cacgaactgc tcgacacgcg cacgcacgag ctggaacggt ccaattcgga
    38761 cctggagcag ttcgcctacg tcgcctcgca cgacctgcag gagccgctgc gcaaggtggc
    38821 gagcttctgc cagctcctgc aacgcaggta ttccgggcag ctcgacgaac ggggcgagca
    38881 gtacatcgag ttcgccgtcg acggcgcgaa gcggatgcag aacctgatca acgatctgct
    38941 gtcgttctcc cgggtgggca ggcgcgcagg cgaccacgtc gtcgtcgaca ccggcgctct
    39001 tctcgaccag gcgctggcga acctggatcc cgtggtcgag gaaaccggtg ccgtcctcac
    39061 ccgcggcgcg ctgcccgagg tgcggggcga ggcgacgctg ctgaccgcgg tgctgcagaa
    39121 cctcgtcaac aacgcgctga agttccgggg cgaggctccg ccggaagtgc gcgtcgaagc
    39181 ggagcgcgac ggcgccgaat gggtgttttc ggtgaccgac aacgggatcg gcatcgacga
    39241 cgagtacgcc gaacggatct tcgcgatctt ccagcgcctg cacgccaaga gcgcctaccc
    39301 gggcaccggg atcgggctgg cgatgtgccg caagatcatc gagtaccacg gcgggcggat
    39361 ctggctcgac accaccgccg ccgaagggac ccgcttccgc ttcaccctgc ccgcgctcga
    39421 ggagccggag gccgtggagc ccgtcgaaaa cgcggaccat gtgaaaagtg aggaagaatg
    39481 accgaatcgc tggacccgat cgacatcctg ctcgtcgagg acgaccccgg tgacgtcctg
    39541 atgacgaagg aggcgttcga gcaccacaag atccggaaca ccctgtcggt ggtcgcggac
    39601 ggcgtggagg cgttgcagtt cctccgccgg gaagcgccgt acgaggacgc gccgaggccg
    39661 gggctgatcc tgctcgacct caacctgccc cgcatggacg ggcgcgaggt gctcagcgag
    39721 atcaaggcgt cgccggacct gcgcaccatc ccggtcgtgg tgctgaccac ctccgaggcg
    39781 gaggaggaca tcctgcgcag ctacgacctg cacgccaacg cctacgtcac caagccggtg
    39841 gacttcgacc ggttcgtcga agtggtccgc cagatcgacg acttcttcgt caccgtggtc
    39901 aagctccccc gctgaagcgc acgggccgct cccgctgaag gccaccatca cgggcagtga
    39961 tggtggcctt cagggcgtgg aaacccgctc agacgcgcgc catgcggcgc acgacgcgca
    40021 gcgccaccac gagcagtacc gcggccagca cgacgaagag gccgaactcg gcgagctgga
    40081 agaacccgag ccgctccggg ggctgggtat cgcggtagtg cgccacgatt ccgttctgcc
    40141 gcaagcagga gtagtactcc cccgcggagc ggtacgagcc gctgcaggaa cgcgggtagt
    40201 ccatcgtggt gcccgcgccg tccagataac cggagtcgac cgtcagcgtg ttgggcggca
    40261 gttcgttcgt cgcggggcct tccacgccga gcgggctcgt ctgccgcacc gggctctgga
    40321 agtacgggcg cacgaaccgt tcgatgcccg cgcgcacccc gacgaacagc gccgccgtga
    40381 cccccatcga caccacggtc cggcggcaga tcgcgctcac cgcgagcccg agcgcgaagc
    40441 cgaacaacgc gtacgcggcc tgggtgagcg cgacgtcgtc gaagtacggc gaccggaaga
    40501 ggttgaacgc cgggtactgg gacggcattt cgaggatgcg gtgcatcatg aactccgcgg
    40561 tcaccccgag cgccacgctg aaggccaccg cgacggccgc gagcacggtc gtcttgaccg
    40621 caagccagcg cagcggggac acgtcctggc tccacaccag caggtgcgtc cgctgctcgt
    40681 actccttcga cagcagcgga gccgcccaga agaccgcgac gagcccgctg aagccgagga
    40741 ccccggcgag caggagttcc ccgacgtccg agacctgccg gacccctggc aggccgatcc
    40801 gggcgtcacc ctgcccggcc acttcgaccg aaacccacag catccccgcg atggcggcga
    40861 gcacgagcac gccggtgccc accagcatca gccggtgctg gcgcgcggtg accccgatca
    40921 gatcgcccca gccgacccgg gcgcgcggtg accgttcggc cacgacagcg gtcgcggtca
    40981 tgcccgtcct cccttcctgg tcctggcgag ctgcgccagt acgaagtctt cgagcgtcac
    41041 cgggcgcacc gtccac
//
