LOCUS       NZ_CP076103            10852 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Lysobacter capsici strain NF87_2 chromosome, complete genome.
ACCESSION   NZ_CP076103
VERSION     NZ_CP076103.1
KEYWORDS    RefSeq.
SOURCE      Lysobacter capsici
  ORGANISM  Lysobacter capsici
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J., Liu,Y., Liang,X., Zhou,Y. and Liu,J.
  TITLE     Characterization of Lysobacter capsici strain NF87-2 and its
            biocontrol activities against phytopathogens. European Journal of
            Plant Pathology
  JOURNAL   Eur J Plant Pathol 155 (3), 859-869 (2019)
REFERENCE   2  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J. and Liu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2021) Institute of Plant Protection, Jiangsu
            Academy of Agricultural Sciences, No. 50 Zhongling Street, Nanjing
            210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: nextDenovo v. 2.0-beta.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018732085.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 13:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,303
            CDSs (total)                      :: 5,240
            Genes (coding)                    :: 5,174
            CDSs (with protein)               :: 5,174
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 16 of 66
            Pseudo Genes (incomplete)         :: 52 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:02:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6180781
            Orig. end                         :: 6191633
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076103.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10852
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="16"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10852
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10852
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5852](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5852)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    286..300
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(729..2132)
                     /locus_tag="KME82_RS25850"
                     /old_locus_tag="KME82_25850"
     CDS             complement(729..2132)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019466478.1"
                     /locus_tag="KME82_RS25850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25850"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_215496590.1"
                     /transl_table=11
                     /translation="MNASTQGPTDASSNASAKAPIARTGSRWLPRTLASRLSLILLSGL
                     LIAHALSFGLLFYERYSAATSMLMSNLEQDVVVAVNLLDRLPPQERERWLPMLRRRTFH
                     YMLDDGAADAAARNQPPVSGTSQDMAAMIASALGPRYPTRANAVPGDGEHFQVHLKLSD
                     GAAMVIDVRPSVMPLAKWLPYVLAIQLALLLLCTWAAVRLTTRPLGRLAKAAETLHPAG
                     EGERLPVGGPTEVAQAITAFNAMQDRIAHYMRERLQILAAISHDLQTPITRMQLRAEAM
                     DESAERDKMFDDLGQMQHLVREGIAYARSAHGASEPAVRIDLNAFLDSLVYDYLDTGRP
                     VTFAGRVDGPVTTRPHALRRIVGNLIDNAIHYAGAAELDVGHDPDGGVRIQVRDRGPGI
                     PEDELGKVMEPFYRLETSRNRSTGGTGLGLAIAQQLAESIGATLVLRNRDGGGLEAILR
                     IAGPIAAAR"
     gene            complement(2129..2869)
                     /locus_tag="KME82_RS25855"
                     /old_locus_tag="KME82_25855"
     CDS             complement(2129..2869)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="KME82_RS25855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25855"
                     /product="response regulator"
                     /protein_id="WP_036113045.1"
                     /transl_table=11
                     /translation="MDHVDHILVVDDDREIRQMVADYLHKNGLRATVAADGREMRALLD
                     THAVDLIVLDLMMPGEDGLTLCRNLRAGKHRAIPVVMLTARDDQTDRIIGLEMGADDYV
                     TKPFAARELLARIKAVIRRTRMLPPNLQVTQASRTIAFGRWRLDTTARHLLDPDDTVVA
                     LSGAEFRLLHVFLDHANRVLTRDQLLNLTQGRDAEHFERSIDLLVSRLRQRLQDDAREQ
                     SYIKTVRSEGYVFSMPVSLLGDGE"
     gene            complement(3002..3583)
                     /locus_tag="KME82_RS25860"
                     /old_locus_tag="KME82_25860"
     CDS             complement(3002..3583)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408503.1"
                     /locus_tag="KME82_RS25860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25860"
                     /product="thioredoxin family protein"
                     /protein_id="WP_215496591.1"
                     /transl_table=11
                     /translation="MTPLPETAATARVPDSTGRAVWKSIIAGLALCLSAAACTPAAHAD
                     AARAVAAPEFAGIARWFNTPALSMAGLRGKVVLVEFWTYSCINCLHVAPHVKQWHERYR
                     DQGLVVIGVHTPEYDEEHSAGNLQAAIERLGIAYPVAQDNAYATWNAYGNRFWPALYLI
                     DRDGRIVYRHYGEGEYEVTDARIRALLAQR"
     gene            complement(3580..4251)
                     /locus_tag="KME82_RS25865"
                     /old_locus_tag="KME82_25865"
     CDS             complement(3580..4251)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415657.1"
                     /locus_tag="KME82_RS25865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25865"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_215496592.1"
                     /transl_table=11
                     /translation="MNAKSRTLGGWSLFWLIGLSILAMSALILALNPDTTEAVRSVIRA
                     TARTSFVLFLIAFVASSLAALVPNELTRGLMRERRYIGLSFAFSHLVHLLAILAYGVLN
                     PQFWPGRSAVTNAPGTVGYVFIALLALTSFRFASRHMTAAAWKRLHTAGIWVIAAIFGY
                     SFFKRIPSMSVLYAIPFSILCAAVAVRLVGKWAQANKRRQARSRSLERTSSFPNALEPS
                     S"
     gene            complement(4241..5008)
                     /locus_tag="KME82_RS25870"
                     /old_locus_tag="KME82_25870"
     CDS             complement(4241..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010343982.1"
                     /locus_tag="KME82_RS25870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25870"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_215496593.1"
                     /transl_table=11
                     /translation="MHETLREQQSVLARHLRDPARHPSPPGIEARRLRVYRELFLGSIE
                     SLLAGGFPVIRQTLGDADWSALVRTFYADHRSRTPLFTRIAGEFVEFIETRADAVQLPP
                     WLPELAHYEWVEQALLISDAQPPAHDPDGDLLDGRPLVSPLAMPLAYRWPVLEIGPSHR
                     PKAPPAQVTTLLVHRDRDHQVRFARIAPLVHHLLTSLQSNACRGREHLAALAAQTGGDA
                     DELQAQGLHLLRQLHEQGVVLGTCLAKEPSDER"
     gene            complement(5001..5852)
                     /locus_tag="KME82_RS25875"
                     /old_locus_tag="KME82_25875"
     CDS             complement(5001..5852)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010483448.1"
                     /locus_tag="KME82_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25875"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_215496594.1"
                     /sec_met_domain="DUF692 (E-value: 1.2e-120, bitscore:
                     400.0, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTIPSLSAGLGLRRGLLPSLLAMDAAAVDFLEVAPDNWIGVGGR
                     FGEALSELSARFPLSCHGLSLSLGGSEPLDMDLLHATRQFNDRHGIALYSEHLSYCADD
                     GHLYDLMPIPFTDEAIGHVAARIRQVQDVLGRRIAVENVSYYAAPYQALAEIDFIRAVL
                     DEADCDLLLDVNNLYVNAINHGYDAQAFLARLPGERIASYHIAGHYDEAADLKIDTHGA
                     PVKADVWSLLDSAYRRFGVRPTLLERDFNFPPLPELLAETDRIRAMQALHADVAQPEPA
                     HA"
     gene            complement(5917..6513)
                     /locus_tag="KME82_RS25880"
                     /old_locus_tag="KME82_25880"
     CDS             complement(5917..6513)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659349.1"
                     /locus_tag="KME82_RS25880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25880"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_252255554.1"
                     /transl_table=11
                     /translation="MSVHNPRSASRSTTAGMLGVALAGLVLGQSAFAMQPLAQGYMVAA
                     SHAAGEGKCGEGKCGAGKTAEGKCGAKAKAAGKAAEGKCGEGKCGAAKAAGKTAEGKCG
                     ANANSASKTAEGKCGEGKCGDASFAKTDRSGDGRVSRAEFLAVAPARAADFPKLDVDGD
                     GFISEQEAYDYLKATYAANGKPMPAGVFAKFTGGK"
     gene            complement(6606..7247)
                     /locus_tag="KME82_RS25885"
                     /old_locus_tag="KME82_25885"
     CDS             complement(6606..7247)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="KME82_RS25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25885"
                     /product="DoxX family protein"
                     /protein_id="WP_215496595.1"
                     /transl_table=11
                     /translation="MSRVDGVAPWLAPLGLRVLLAWEFFEAGREKLQGDNWFADLGDKF
                     PLPFSLLGADLNWTLATWTELAGAAALLLGLGTRYVATALWVLTVVAIYAVHWPSDWSS
                     LAELWQGYAISDDGHGNYKLPLIYLAMLLPLMLGGAGRLSLDRLLASRRAPVATAQADR
                     LAWGVVLLGLGATVSLLLPWVGATLAFAGIALTIKPRDRNASNRLSSAVA"
     gene            7608..8852
                     /locus_tag="KME82_RS25890"
                     /old_locus_tag="KME82_25890"
     CDS             7608..8852
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF018485.4"
                     /locus_tag="KME82_RS25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_25890"
                     /product="MFS transporter"
                     /protein_id="WP_215496596.1"
                     /transl_table=11
                     /translation="MNDTTASSPTLDRNWALVAAGALMGCVAIGAVFSLAVLLQPMSTA
                     TGWSRAGLSSAMTLAFLSMGFAGFGWGVLSDRFGPRVVVLAGSVLLGLACVLASRAGSL
                     LQFQLSYGVLLGAAAASFFAPVIAAVAASFERRRNLAISLVSAGMGVAPMTLSPLVAWL
                     VGDYGWRSSLLIVGVLAWALTLPAVWFVRSVPASASAGAADSGSDSSTLSAAQALRSRP
                     FTVLGAAFFACCAAHSGPIFHTVSYAVGCGLSVTAAVTIYSMEGAAGLGGRLLLGVLAD
                     RFGAKPVLVAGLLLQAFAALAYLAVNQLDGFYAVAIVFGMAYGGTMPLYASLARDAFSP
                     AILGTVLGAATLLSSLGMALGPLIGGGLYDHYGSYTWLYVGSMAMGLAAAAIAMLFPSA
                     RRPRMRDALKPALQP"
     misc_feature    8914..8923
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(8972..8987)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(8992..9001)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(9193..9202)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    9641..9652
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    10208..10221
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
ORIGIN
        1 gatacagatg gtgccgcgat gcgcggtcga gattgttcga cggctcgtcc agcaacagca
       61 ggtcgggccg ccgcagcagt tgcgcggcga tgccgaggga gacgatttcg ccgccgctga
      121 agctgtccag gcgccgctgc agggcgatat cgctcaaacc cagccgggcc aggtcggcgc
      181 gcgtgcgttc ctcgatgtcc cagtcctcgc cgacggtatc cagcagcgaa gggtccatcc
      241 caccctcggc gatggcccgc aaggcatcga gcctggcgcg aatgccgagc acttcggcca
      301 cgctcgcatc gcccgacagc ggcaggtgct gcggcaggta agccacgacg ccgtgagtct
      361 cgacctgccc ggccgtgggc gcgagctgcc cggccagcag ccgcatcagc gtgctcttgc
      421 cgctgccgtt gggcccgacc agcccgctgc gctgcggacc gaagctgcac gacagcccgt
      481 cgaacacggg cgtgccgtcc ggccaggaaa aaccgagatt tgaagcgcgc aggcacaagc
      541 cgcgaaagga aacatccgtc atcgacgatc tccatcggtg ccgcgcggac gcgagcgatc
      601 gcgcggcggt cagaccacga ccgatccgcg gcgcgcgcgt tcggcgcggc agggcggatg
      661 ggtcggcgtg aggtcccggg aagtcgtctg attacatgcg ggctgccggt tgaacgttgc
      721 gcactagttt accgcgccgc ggcgatcggg ccagcgatgc gcaggatcgc ttccaggccg
      781 ccgccgtcgc gattgcgcag caccagcgtg gcaccgatcg attcggccag ttgctgggcg
      841 atcgccaaac ccaggccggt gccgccggtg ctgcgattgc gcgaggtttc gagccggtag
      901 aacggctcca tcaccttgcc cagttcgtct tcgggaatgc cggggccgcg atcgcgcacc
      961 tggatgcgca cgccgccgtc cgggtcgtgg ccgacatcga gttcggccgc gccggcgtag
     1021 tggatcgcgt tgtcgatcag attgccgacg atgcgccgca acgcatgcgg acgcgtggtc
     1081 accgggccgt cgacgcggcc ggcgaaggtg accggtcggc cggtgtcgag gtagtcgtag
     1141 accaggctgt cgagaaaggc attgaggtcg atccgcaccg ccggctcgga cgcgccgtgc
     1201 gcgctgcgcg catacgcgat gccttcgcgc accagatgct gcatctggcc gaggtcgtcg
     1261 aacatcttgt cgcgctcggc cgattcgtcc attgcttcgg cgcgcagctg catgcgggtg
     1321 atcggcgtct gcaggtcgtg cgagatcgcc gcgaggatct gcaggcgttc gcgcatgtag
     1381 tgggcgatgc ggtcctgcat ggcgttgaac gcggtgatcg cctgcgccac ttcggtcggg
     1441 ccgccgaccg gaagccgctc gccctcgccg gccggatgca gggtttcggc ggctttcgcc
     1501 agccggccga gcggccgggt ggtcagccgc accgcggccc aggtgcacag cagcagcagc
     1561 gccagttgga tcgcgagcac gtagggcagc cacttcgcca gcggcatcac cgaggggcgc
     1621 acgtcgatga ccatcgcggc gccgtcgctc aatttcagat gcacctggaa gtgttcgccg
     1681 tcgccgggca cggcattggc gcgggtcggg tagcgcgggc cgagcgcgct ggcgatcatc
     1741 gcggccatgt cctgcgaggt gccgctgacc ggcggttggt tgcgggcggc cgcgtcggcg
     1801 gcgccgtcgt cgagcatgta gtggaaggtg cgccgccgca gcatcggcag ccaacgctcg
     1861 cgttcctgcg gcggcaggcg gtcgagcaga ttcaccgcga ccaccacgtc ctgttccaga
     1921 ttgctcatca gcatcgaggt cgccgccgaa tagcgctcgt agaacagcag gccgaacgac
     1981 agcgcatgcg cgatcagcag gccgctgagc aggatcagcg acaggcgcga ggccagcgtg
     2041 cgcggcagcc agcgcgaacc ggtgcgggcg atcggcgcct tcgccgacgc attcgaagat
     2101 gcatccgtcg gtccctgggt cgacgcgttc attcgccatc tcccagcaga ctcaccggca
     2161 tgctgaacac atagccttcg ctgcgcacgg tcttgatgta gctctgctcg cgcgcgtcgt
     2221 cctgcaggcg ctggcgcagg cggctcacca acagatcgat ggagcgttcg aagtgctcgg
     2281 cgtcgcggcc ctgggtgagg ttgagcagct gatcgcgggt gagcacgcga ttggcgtggt
     2341 cgaggaacac gtgcagcagg cggaactcgg cgccgctgag cgcgaccacg gtgtcgtcgg
     2401 gatcgagcag atggcgcgcg gtggtgtcca ggcgccagcg tccgaacgcg atggtgcggc
     2461 tggcctgggt gacctgcagg ttcggcggca gcatgcgcgt gcgccggatc accgccttga
     2521 tccgcgccag cagttcgcgc gcggcgaacg gcttggtgac gtagtcgtcg gcgcccatct
     2581 ccaggccgat gatgcggtcg gtctgatcgt cgcgcgcggt cagcatcacc accgggatcg
     2641 cgcggtgctt gccggcgcgc aggttgcggc acagggtcag gccgtcttcg ccgggcatca
     2701 tcaggtcgag cacgatcaga tcgaccgcgt gggtgtcgag cagggcgcgc atctcgcgac
     2761 cgtccgcggc gaccgtggcg cgcaggccgt tcttgtgcag atagtcggcg accatctggc
     2821 ggatctcgcg atcgtcgtcg acgaccagga tgtgatctac gtggtccatg cggggcctgt
     2881 gcgatgcgcg gtgaaggatg gagccggcgg cgggacgttg gcggagattg tgccaccgcg
     2941 cggccgtcgc gccgcggcga gttgctcgcg ccagccgctg ttcggctcgc cgccgcgtcc
     3001 ctcagcgctg cgccagcagc gcgcggatac gcgcgtcggt gacctcgtac tcgccttcgc
     3061 cgtaatggcg gtagacgatg cggccgtcgc ggtcgatcag gtacagcgcc ggccagaacc
     3121 gattgccgta agcgttccag gtggcgtagg cgttgtcctg cgcgaccgga tacgcgatgc
     3181 ccaggcgctc gatcgcggcc tgcagattgc ccgcgctgtg ttcttcgtcg tactccggcg
     3241 tatgcacgcc gatcaccacc aggccctggt cgcggtagcg ctcgtgccac tgcttcacgt
     3301 gcggcgcgac atgcaggcag ttgatacacg agtaggtcca gaactccacc agcaccacct
     3361 tgccgcgcag cccggccatg ctcagcgccg gggtgttgaa ccagcgcgcg atcccggcga
     3421 attccggcgc ggcgacggcg cgcgccgcgt ccgcatgcgc ggccggggtg caggccgcgg
     3481 cgctcaggca cagcgccagg ccggcgatga tcgacttcca tacggcgcga ccggtcgaat
     3541 ccgggacgcg tgcggtagcg gcagtttcgg gcaacggcgt catgacgaag gctccagtgc
     3601 gttggggaag gacgaggtgc gctccagcga acgcgaacgc gcctggcgtc gcttgttggc
     3661 ctgcgcccat ttgccgacca ggcgcaccgc gaccgcggcg cacaggatcg agaacggaat
     3721 cgcatacagc acgctcatgc ttggaatgcg cttgaagaac gagtagccga agatcgcggc
     3781 aatcacccag atgccggcgg tgtgcaggcg cttccacgcc gccgcggtca tgtggcgcga
     3841 ggcgaagcga aacgaggtca gcgccagcaa ggcgatgaac acgtaaccca cggtgcccgg
     3901 cgcattggtc acggcgctgc ggccgggcca gaactgcgga ttgagcacac cgtaggcgag
     3961 gatcgccagc agatgcacga ggtgcgagaa cgcgaacgac aggccgatgt agcggcgttc
     4021 gcgcatcagc ccgcgggtga gctcgttcgg caccagcgcg gccagcgagg acgccacgaa
     4081 cgcgatcagg aacaagacga acgaggtgcg cgcggtggcg cggatcaccg accgcaccgc
     4141 ttcggtggtg tcggggttca gcgccaggat cagcgccgac atcgccagga tcgacaggcc
     4201 gatcagccag aacagcgacc agccgccgag ggttcgggat ttagcgttca tcgcttggct
     4261 cctttgcaag acaggtaccc aggaccacgc cctgctcgtg cagttgccgc agcaggtgca
     4321 ggccctgggc ctgaagttcg tcggcgtcgc cgccggtttg cgcggccaac gcggcgaggt
     4381 gctcgcggcc gcggcaggcg ttgctctgca gcgaggtcag caggtgatgg accagcggcg
     4441 cgatgcgggc gaaccgcacc tgatggtcgc ggtcgcgatg cacgagcaag gtggtgacct
     4501 gcgccggcgg cgctttgggg cgatgcgaag ggccgatctc cagcaccggc cagcggtacg
     4561 ccagcggcat cgccagcggc gacaccagcg gccggccgtc gagcagatcg ccgtccgggt
     4621 cgtgcgccgg cggctgtgca tcgctgatca gcaaggcctg ctccacccat tcgtaatgcg
     4681 ccagttcggg cagccacggc ggaagctgca cggcgtctgc gcgggtttcg atgaactcga
     4741 cgaactcgcc ggcgatgcgg gtgaacagcg gcgtgcggct gcgatggtcg gcgtagaacg
     4801 tccgcaccag cgcgctccag tccgcgtcgc cgagggtttg gcggatcacc gggaagccgc
     4861 cggccagcag gctttcgatc gagcccagga acaattcgcg gtacacccgc aggcggcgcg
     4921 cttcgatccc gggcggcgac ggatggcggg ccgggtcgcg caggtgacgc gcgaggacgg
     4981 attgctgttc gcgcaaggtc tcatgcatgg gccggctccg gttgcgccac gtcggcgtgc
     5041 aaggcctgca tcgcgcggat gcggtcggtc tcggccagca gttcgggcaa tggcgggaaa
     5101 ttgaaatcgc gttcgagcaa ggtcgggcgc acgccgaagc ggcggtaggc gctgtccagc
     5161 aacgaccaca catcggcctt gaccggtgcg ccgtgggtgt cgatcttgag gtcggccgct
     5221 tcgtcgtagt ggccggcgat gtggtacgag gcgatgcgtt cgccgggcag tcgcgcgagg
     5281 aacgcctgcg cgtcgtagcc gtggttgatc gcgttgacgt agaggttgtt gacgtcgagc
     5341 agcaggtcgc agtcggcttc gtcgagcacg gcgcggatga aatcgatctc ggccagggcc
     5401 tgatacggcg cggcgtagta cgacacgttc tccaccgcga tgcgccggcc gagcacgtcc
     5461 tgcacctggc ggatgcgtgc ggcgacgtgg ccgatcgcct cgtcggtgaa cgggatcggc
     5521 atcaggtcgt acagatggcc gtcgtcggcg cagtagctca ggtgttcgct gtacagggcg
     5581 atgccgtggc ggtcgttgaa ttgacgcgtg gcgtgcagca ggtccatgtc gagcggctcg
     5641 ctgccgccca gcgacaacga caggccgtgg cagctcaacg ggaaacgcgc ggacagttcg
     5701 ctcagcgctt cgccgaagcg gccgcccacg ccgatccagt tgtccggcgc gacttcaagg
     5761 aaatccaccg cggcggcgtc catcgccagc agcgacggca gcaggccgcg gcgcaggccg
     5821 agcccggcgg acagtgaggg gatggtacgc atgcggggct cctggatcgt tcgaaggcgc
     5881 ccccgcgccg aagcgcaggg gcgcgtggac ggcggtttac ttgccgccgg tgaacttggc
     5941 gaacacgccg gccggcatcg gcttgccgtt ggccgcgtag gtggccttga ggtagtcgta
     6001 ggcttcctgc tcggagatga aaccgtcgcc gtcgacgtcg agcttcggga agtcggcggc
     6061 gcgggccggc gccaccgcga ggaattcggc gcgcgagacg cggccgtcgc cgctgcggtc
     6121 ggtcttggcg aacgaggcgt cgccgcactt gccttcgccg catttgcctt cggcggtctt
     6181 gctggcgctg ttggcgttcg cgccgcactt gccttccgcg gtcttgccgg cggccttggc
     6241 ggcgccgcac ttgccttcac cacacttgcc ttcggcggcc ttgccggcgg ccttggcctt
     6301 cgcgccgcac ttgccctcgg cggtcttgcc ggcaccgcac ttgccttcgc cacacttgcc
     6361 ttcgccggcg gcgtggctgg cggcgaccat gtagccctgg gcgagcggct gcatggcgaa
     6421 ggcggattgg cccaggacca ggccggccag ggcgacgccg agcatgccgg cggtggtgga
     6481 acgcgaagca gaacgtgggt tgtggacgga catggtggtt ctccgatggc gcacggcgaa
     6541 gccgcgctga ggtgggcgcc gcggacgcgg cgtgggcgga acgaaggaag gggaacgcgg
     6601 cgcggtcagg cgacggccga ggacaggcga ttggaggcat tgcgatcgcg cggcttgatc
     6661 gtcagcgcga tgccggcgaa tgcgagggtc gcgccgaccc acggcagcag cagcgacacg
     6721 gtcgcgccca gaccgagcaa caccacgccc caggccaggc gatcggcctg cgcggtcgcg
     6781 accggcgcgc gacgcgatgc gagcagtcgg tcgagactca ggcgaccggc gccgccaagc
     6841 atcagcggca gcagcatcgc caggtagatc agcggcagct tgtagttgcc gtggccgtcg
     6901 tcgctgatcg catagccctg ccacagctcg gccaagctcg accagtccga cggccaatgc
     6961 accgcgtaga tcgcgaccac cgtcagcacc cacagcgcgg tggcgacata gcgcgtgccc
     7021 aggccgagca gcagcgccgc ggcgccggcc agttcggtcc aggtcgccag ggtccagttg
     7081 agatcggcgc cgagcagcga gaacggcagc ggaaacttgt cgccgaggtc ggcgaaccag
     7141 ttgtcgccct gcagcttctc gcggccggct tcgaagaatt cccaggccag caggacgcgc
     7201 agaccgagcg gggcgagcca cggcgcgacg ccgtcgacgc gggacatcag gggcactgcg
     7261 ggggttgagg cgacagacat ctcgggttcc ttgaaggagg cggaccgtgc gttccggtga
     7321 cgccatttca agcgcgcggg gtatcgcgca ggtgtccgcc ggcccgggga tttgtctgcg
     7381 aaggtggctg tcgcggcggc cgatacattg cgatacaaat ccgcggggtc gagccgcggc
     7441 gctcgtgtga agcgcgcggg acctcgatgc ccgcctgctt cgcggcgtcg gtccggtaga
     7501 gctcccattg cttcgccggc cgcgggtatt gcgcccgacg cggaggtttg tcgatacgcg
     7561 gtggcctgct tcgtcgtatc agggagcacc ccacgggccg cgcccccatg aacgacacga
     7621 ccgcttcctc ccccaccctg gaccgcaact gggccctggt cgccgccggc gcgctgatgg
     7681 gctgcgtggc catcggcgcg gtgttctcgc tggcggtgct gctgcagccg atgagcaccg
     7741 cgaccgggtg gtcgcgcgcc gggctgtcca gcgcgatgac cctggcgttc ctgagcatgg
     7801 gcttcgccgg cttcggctgg ggcgtgctca gcgaccggtt cgggccgcgg gtggtggtcc
     7861 tggccggctc ggtgctgctc ggcctggcct gcgtgctggc cagccgcgcc ggcagtctgt
     7921 tgcagttcca gctcagctac ggcgtgctgc tcggcgccgc cgcggccagt ttcttcgcgc
     7981 cggtgatcgc ggcggtcgcg gcctcgttcg aacggcggcg caacctcgcc atctcgctgg
     8041 tgtcggccgg catgggcgtg gcgccgatga ccctgtcgcc gctggtggcc tggctggtcg
     8101 gcgactacgg ctggcgcagc agcctgttga tcgtcggcgt gctggcgtgg gcgctgacct
     8161 tgccggcggt gtggttcgtg cgcagcgtgc cggcgtcagc atccgccgga gccgccgaca
     8221 gcggcagcga cagcagcacc ctgagcgccg cgcaggcgtt gcgctcgcgg ccgttcaccg
     8281 tcctcggcgc ggcgttcttc gcctgctgcg cggcgcattc cgggccgatc ttccacaccg
     8341 tcagctacgc ggtcggctgc ggcctgtcgg tgaccgcggc ggtgacgatc tacagcatgg
     8401 aaggcgcggc cgggctcggc ggtcgcctgc tgctgggcgt gctcgccgat cgcttcggcg
     8461 ccaagccggt gctggtggcc ggacttttgc tacaggcatt cgcggcgctg gcctatctgg
     8521 cggtgaatca gctcgacggg ttctacgcgg tggcgatcgt gttcggcatg gcctacggcg
     8581 gcaccatgcc gctgtacgcc tcgctcgcgc gcgatgcgtt cagtcccgcg attctcggca
     8641 ccgtgctcgg cgcggccacc ttgctgtcga gcctgggcat ggcgctcggc ccgttgatcg
     8701 gcggcgggtt gtacgaccac tacggcagct acacctggct gtacgtcggc tcgatggcga
     8761 tgggcctggc cgcggcggcg atcgccatgc tgtttccgtc ggcgcggcgg ccgcggatgc
     8821 gcgacgcatt gaaacctgcg ttgcagccgt gacggatcgt tatcgatgac gcgctcgcac
     8881 cgagatgcag cgagaacttc ggcaaatatc agccgttttt ttcctgtccg aatacaggaa
     8941 aggccgatga gcacgccatc ggcctttccg cttttacgtc tgaaatcgca cggccgcctt
     9001 catcgcgacc gccgaccgtc gcccaggatc aatgccagtt gaggttgacc gacaccccga
     9061 cgatgcgcgg ctcgttgtag accgcagcca tgtagttctc gatcacgccc ttgaggttct
     9121 tctcgttggt gatgttgcgc gcgaacaagg cgacctcgta agcgccgtag ccgccggtgt
     9181 aacccacctt caggccgcct tcgaaattgc cgctggcgtt gaattccttc gagtcgtaca
     9241 ggacgaagct ggtgtagccc tgcttgttcc agtcggtggc gacgaacagc gcgccgctgt
     9301 cgctcagcgg aatgtcgtag cgcgcgccca ggttgacgct gtacttgggc gcgttcggca
     9361 acgggttgcc gtcgatctgg gcgaaggtgt tggcgccgac cttgatggtc gggtcctcga
     9421 ccgtgcatac caccgcgccg ttgagcgcgc agacctgcgc gtacacgcgc ttgtcctgga
     9481 tttcgctgtg cagcaggctc acgccggcgg tcagcgacag gttcgggatc gggcgccagt
     9541 ccaggtcggc ttccacgccg taggcacggg ccttgtcggc gttgaacagc acgccgttgc
     9601 cgttggagtc gttgccgttg agctggatgt cgtcgacggt gtaggtgaac gcggtcgcgt
     9661 tcaaacgcag gcggttgtcg agcaggctgc tcttgatgcc cgcctcccac gacagaatgg
     9721 tttccgaatc ggcggtggtg aagtcggcgt tgaacaccgc cgagcggccc tggatggtcg
     9781 ggccgcggaa gccgcgcgcc accttggcgt acacgctgag gttcgggttg atctcgtaca
     9841 tcgcgctcag gtcccagctg ggctgggtat cggacatgcg cacgtcgcgg cggccggtgt
     9901 aggtcgacac gccggcggcg gtgtcggcgg tcttgagcag gcgcgtttcc ttgctgtcgc
     9961 gggtctggcg caggccggcg gtcagggtca gcgcgtcgtt aaccttgtag ctgagctggc
    10021 cgaacgcggc ccacgaggtg ttggagttgc gcagacgcac ccagttgttg ggattgcgcg
    10081 ccgggccctt gaggaaccac gcgcgctgat agaaatcggt ggtgtcgcgg ccgtcgaagt
    10141 agaacgcgcc gacctgccat tgcagcgcgt cgtcggtctc gctggccaga cggaattcct
    10201 gggtgaattg atccagatcg cggatctgcc ccatcgactg gccgaaaccg ttgggcacgc
    10261 cgcgcaccgg gtagttcgcc gcggcgccgc cgtcggtgtc gccgcggctg tagccggagg
    10321 tggtttcgta ggcgctgatc gaggtcagcg aggtctcgcc gaagttgtag gtggccttga
    10381 tcgagccgcc gtaggtcttg tacgcctgcg ggttgttgcc ggcttcgtca taggcgacct
    10441 tgtcgcgcgg cacgtcgact tcgttggagc ccttgacgat ggcgttgcgc aggaacagcg
    10501 tcgaggtgcc cgagtaatcg cgcgcgtgcg ccgaggcgag gatcgagaag ttctcgctcg
    10561 gcgccagcag cagttgcacg cgcaggttgc ggtcgtcgaa gccgcccatc gcgtctttct
    10621 tcggcgtgac cgtgccgtcg gcgctggcgc cggcgaaggt gttgtcgacc cagtcgtcgc
    10681 ggtgctggta cagcgtggac acgcggaacg acagcacgtc gttgatcggg ccgccgatgc
    10741 cgccgtcgat cgacacggtg ttgtagctgc cgacgctggc ctgcacccgg ccgctgaaat
    10801 cctggctcgg cttgatgctg tcgaacttga tgatgccggc ggtggtgttg cg
//
