LOCUS       NZ_CP076103            22865 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Lysobacter capsici strain NF87_2 chromosome, complete genome.
ACCESSION   NZ_CP076103
VERSION     NZ_CP076103.1
KEYWORDS    RefSeq.
SOURCE      Lysobacter capsici
  ORGANISM  Lysobacter capsici
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J., Liu,Y., Liang,X., Zhou,Y. and Liu,J.
  TITLE     Characterization of Lysobacter capsici strain NF87-2 and its
            biocontrol activities against phytopathogens. European Journal of
            Plant Pathology
  JOURNAL   Eur J Plant Pathol 155 (3), 859-869 (2019)
REFERENCE   2  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J. and Liu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2021) Institute of Plant Protection, Jiangsu
            Academy of Agricultural Sciences, No. 50 Zhongling Street, Nanjing
            210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: nextDenovo v. 2.0-beta.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018732085.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 13:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,303
            CDSs (total)                      :: 5,240
            Genes (coding)                    :: 5,174
            CDSs (with protein)               :: 5,174
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 16 of 66
            Pseudo Genes (incomplete)         :: 52 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:02:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5463846
            Orig. end                         :: 5486711
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076103.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22865
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="12"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22865
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22865
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12865](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12865)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            544..1035
                     /locus_tag="KME82_RS22755"
                     /old_locus_tag="KME82_22755"
     CDS             544..1035
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409399.1"
                     /locus_tag="KME82_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22755"
                     /product="hypothetical protein"
                     /protein_id="WP_215496039.1"
                     /transl_table=11
                     /translation="MLKQKDALGKFLAVAICLSGFSAVAHDAVAGGWVESGRTAYYKNS
                     FFGSFDSHTCSVGGPDFAGFPGSCPNDGASGWNSNFTASFDLSSSDLNICNFDPHSPGS
                     SCDTQAYAVNGQAVRGGLPANCTVGTRAVASWGRKETIVIQYEELDVETTEQAREYVCQ
                     "
     gene            1220..2185
                     /locus_tag="KME82_RS22760"
                     /old_locus_tag="KME82_22760"
     CDS             1220..2185
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013533876.1"
                     /locus_tag="KME82_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22760"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_215496040.1"
                     /transl_table=11
                     /translation="MTRTPVSALAAALVAGALLSACSQPKSAATDTPAATTPAASAPAP
                     PAPQPANADVFRFKIGALDAMALKDGDIDAANDGKTFAVGQPVDAVNALLTAAGQPTDT
                     LHLSIQPLLVRSGAQVLLFDTGAGDASFARAGRLPASLRAAGVEPSQVTDIFLSHHHPD
                     HVGGLLDKDGTLAFANAKIHLSAPEWEVMKNDKAAAALVAAIAPKVETFQPGAAIVPGV
                     VTAVAVDGHTPGHSAYEIASGDQRLLYIGDSAHHSVISVQRPEWTVQFDENAPLAQTSR
                     RALMQRAADGKLRVYAVHFPFPGLGQFKAQGDSFVWEPER"
     gene            2365..3351
                     /locus_tag="KME82_RS22765"
                     /old_locus_tag="KME82_22765"
     CDS             2365..3351
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009459580.1"
                     /locus_tag="KME82_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22765"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_215496041.1"
                     /transl_table=11
                     /translation="MQTATPQPVVSRLTRAAIFLVVTLKPGAEHETQVRALCADLASLL
                     RAVGFRDLEGGLSCVMAFGSDAWDRLFGPIRPRELHPFREIVGRHRAVSTPGDVLLHIR
                     AARMDLCFELATEIMSRIGGAVASADEVHGFKYFDDRDLIGFVDGTENPVDTAAADAAI
                     VAGEDPQFVGGSYVIVQKYLHDLAAWNTLPVERQEAIVGRRKLSNIELDDAAKAPYAHN
                     VLTSISENGEELKIVRDNMPFGSVGQGEFGTYFIGYARSPTRIERMLENMFIGDPPGNY
                     DRLLDFSTAVTGSLFFAPSATFLDGVEAEAAAPKGAADHGHDRSIGP"
     gene            3348..4253
                     /locus_tag="KME82_RS22770"
                     /old_locus_tag="KME82_22770"
     CDS             3348..4253
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013705.4"
                     /locus_tag="KME82_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22770"
                     /product="DnaJ C-terminal domain-containing protein"
                     /protein_id="WP_215496042.1"
                     /transl_table=11
                     /translation="MNSPYETLGVAPTASLDEIKSAYRRLARKLHPDLNPGDKSGEERF
                     KDVGNAYRLLSDPDKRARFDAGEIDADGAERPQPRYYRDYADAEPAGSYANDAGFADFA
                     DGDDPFAELLRRQARARANRRGQDLHYRLQIALAESIDAGTRRLTMPDGSTIDVTIPAG
                     VVDGQILRLKGKGAASAGQGGPGDALVEIEVLADPRFSRDGDDLTLELPVSLTEAVLGD
                     RVRVPTPTGEVTMTIPPGSNSGTTLRLKGMGAPRRGGGRGDQYVRLTIVLPKGGDPELT
                     EFVSQWSAGKAFDPRGEAKA"
     misc_feature    3756..3758
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4250..4555
                     /locus_tag="KME82_RS22775"
                     /old_locus_tag="KME82_22775"
     CDS             4250..4555
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024979.4"
                     /locus_tag="KME82_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22775"
                     /product="chaperone modulator CbpM"
                     /protein_id="WP_215496043.1"
                     /transl_table=11
                     /translation="MNTIDMTQFLNESTIELHTLERWIEQRWIIPSQGTARVEISETDA
                     ARAIFIRDLTGDLGVNEEGVAVVLHLVDQLHGLRRALTELRIEMNASRGDPGHESD"
     CDS             4701..4790
                     /gene="allorf_5468547_5468636"
                     /locus_tag="allorf_5468547_5468636"
                     /protein_id="allorf_5468547_5468636"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRLSSGHDARAAAVQSPFLPRCTTTRCLR"
     CDS_motif       4701..4739
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRLSSGHDARAAA"
                     /locus_tag="allorf_5468547_5468636_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4740..4790
                     /prepeptide="core"
                     /locus_tag="allorf_5468547_5468636_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1806.1"
                     /monoisotopic_mass="1805.0"
                     /core_sequence="VQSPFLPRCTTTRCLR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRLSSGHDARAAA"
                     /leader_location="[4700:4739](+)"
                     /alternative_weights="1824.2"
                     /alternative_weights="1842.2"
     gene            4787..5476
                     /locus_tag="KME82_RS22780"
                     /old_locus_tag="KME82_22780"
     CDS             4787..5476
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KME82_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KME82_22780"
                     /product="hypothetical protein"
                     /protein_id="WP_215496044.1"
                     /transl_table=11
                     /translation="MKSLKRSAQCLMLGLTLSMALSAQAQTVGYNIRTGDVWVDTRLGE
                     INDYGRRYPEPFVDEVSGYYGAPRPYVEELLQRRRWAPGDVYYACALAHSLGVPCQNVV
                     REYDRNPGQGWGAVAKRMGIKPGSPAFHALKRGAVTTYDRWGYPIRVDQSVHVNWADHG
                     PGKGHGKSKGPDHRSYDSGHSYPQGHGKGKGPKGGDSHGNGKGHGKDKDKGHGNGNGKG
                     NGKGHEH"
     CDS             complement(5647..5757)
                     /gene="allorf_5469493_5469603"
                     /locus_tag="allorf_5469493_5469603"
                     /protein_id="allorf_5469493_5469603"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MQGRALRGGCRSDRLTLAASNHSGTWMHTESVGAVR"
     CDS_motif       complement(5731..5757)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQGRALRGG"
                     /locus_tag="allorf_5469493_5469603_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5647..5730)
                     /prepeptide="core"
                     /locus_tag="allorf_5469493_5469603_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="2817.1"
                     /monoisotopic_mass="2815.4"
                     /core_sequence="CRSDRLTLAASNHSGTWMHTESVGAVR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQGRALRGG"
                     /leader_location="[5730:5757](-)"
                     /alternative_weights="2835.1"
                     /alternative_weights="2853.1"
                     /alternative_weights="2871.2"
                     /alternative_weights="2889.2"
                     /alternative_weights="2907.2"
                     /alternative_weights="2925.2"
     gene            complement(5762..6622)
                     /locus_tag="KME82_RS22785"
                     /old_locus_tag="KME82_22785"
     CDS             complement(5762..6622)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018684.4"
                     /locus_tag="KME82_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22785"
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="WP_286673224.1"
                     /transl_table=11
                     /translation="MSAALLGGPAHALDCRKASTGLEHRLCADPGLRKADAAMGKAYFD
                     LLGLATDPEVRAALINSQRRWIAAREKDLGGLGEGEDAPNADEQRAILLDATAQRTKYL
                     SERVGGTPKLIADAMKQRARVAAYSGGSFAGYRANCAFIPDRQDRAVYSYNCFGVMNVQ
                     NGDRICSVSEDFASHYVVMQRAVADVVGGKPRVIAACVDSQCPGVSVTGQAAGWNFDPT
                     PEQADIVESFGPLNKLDPDIAVLSDDDDWLALPGLRADQGWLNACLTDKSFPKRGRVSD
                     GHGRK"
     gene            complement(6773..7282)
                     /locus_tag="KME82_RS22790"
                     /old_locus_tag="KME82_22790"
     CDS             complement(6773..7282)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025292.4"
                     /locus_tag="KME82_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22790"
                     /product="lipocalin-like domain-containing protein"
                     /protein_id="WP_215496046.1"
                     /transl_table=11
                     /translation="MKAGIFVSIAASLSIGCATAAANAAKDGAGSLSSRLVGTWQVVEM
                     VDTDAAGTTRHPYGEHPTGYIVYDATGHMHVQVMRTPATPPFAAGDQKGSEREVRAAYD
                     GYVAYFGTYRVDEAQGRVIHQVQGSLMPSYTGTDQPRPIKLVGDELIIEGSTPDGGFYR
                     RLRRVN"
     misc_feature    complement(7301..7310)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     CDS             7459..7551
                     /gene="allorf_5471305_5471397"
                     /locus_tag="allorf_5471305_5471397"
                     /protein_id="allorf_5471305_5471397"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSYLAHDGSVAASPMRPCLHRPARTSGIQT"
     CDS_motif       7459..7497
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSYLAHDGSVAAS"
                     /locus_tag="allorf_5471305_5471397_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7498..7551
                     /prepeptide="core"
                     /locus_tag="allorf_5471305_5471397_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="1867.2"
                     /monoisotopic_mass="1866.0"
                     /core_sequence="PMRPCLHRPARTSGIQT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSYLAHDGSVAAS"
                     /leader_location="[7458:7497](+)"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     gene            complement(7604..7930)
                     /locus_tag="KME82_RS22795"
                     /old_locus_tag="KME82_22795"
     CDS             complement(7604..7930)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019498.4"
                     /locus_tag="KME82_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22795"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_215496047.1"
                     /transl_table=11
                     /translation="MSTGNLFVDADAPAQGERFETLLTHNNLVVERIVSSAATIPVEYV
                     QTQDEWVALLQGEATLEVAGESMELVCGGYVFLPAGTPHTVRRVSQGAVWLAIHLHPAA
                     APND"
     misc_feature    8093..8109
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
     gene            <8172..8267
                     /locus_tag="KME82_RS26855"
                     /pseudo=""
     CDS             <8172..8267
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="KME82_RS26855"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="TVRTHIESVFRKLECSTRAAATLKAAQLGLL"
     gene            complement(8313..8984)
                     /locus_tag="KME82_RS22800"
                     /old_locus_tag="KME82_22800"
     CDS             complement(8313..8984)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009403894.1"
                     /locus_tag="KME82_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22800"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_252255483.1"
                     /transl_table=11
                     /translation="MSFSDPQAVARYAQGPVRQVPGFHALQQMTMLLLAEAVAHDGRVL
                     VLGAGGGLELKVFAEAQPEWRFVGVDPSAEMLKLANDTLGPLASRVELCEGYIDTAPDG
                     PFDGATCLLTLHFLPADERLRTLIELRRRLKPGAPLIVAHHSVPDDGKLRWLQRYAAFA
                     VASGGIPAENASKSVAALDSRLPMLSPEHDEALLREAGFEHVELFYAAFTFKGWVAYNP
                     F"
     misc_feature    complement(9005..9019)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(9059..9072)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.86"
                     /tool="antismash"
     misc_feature    9081..9096
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.34"
                     /tool="antismash"
     gene            9238..9549
                     /locus_tag="KME82_RS22805"
                     /old_locus_tag="KME82_22805"
     CDS             9238..9549
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KME82_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KME82_22805"
                     /product="hypothetical protein"
                     /protein_id="WP_215496048.1"
                     /transl_table=11
                     /translation="MWIVRSIDPNHIVLRAWSRERGRKDFPLEVRMRFDDPWLNYGPII
                     TAPSERRHEFFELAPVTPKTVRWAIDAAIAAGWNPHKPREHRLFERGSNGDLVSVRSS"
     CDS             9797..9949
                     /gene="allorf_5473643_5473795"
                     /locus_tag="allorf_5473643_5473795"
                     /protein_id="allorf_5473643_5473795"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDVRRAPPGQDVPCGACPRKRRTRGHSIHKKTFFFGYLLTEGNPD
                     RIFSL"
     CDS_motif       9797..9844
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDVRRAPPGQDVPCGA"
                     /locus_tag="allorf_5473643_5473795_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9845..9949
                     /prepeptide="core"
                     /locus_tag="allorf_5473643_5473795_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="3989.6"
                     /monoisotopic_mass="3987.2"
                     /core_sequence="CPRKRRTRGHSIHKKTFFFGYLLTEGNPDRIFSL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDVRRAPPGQDVPCGA"
                     /leader_location="[9796:9844](+)"
                     /alternative_weights="4007.6"
                     /alternative_weights="4025.6"
                     /alternative_weights="4043.7"
                     /alternative_weights="4061.7"
     gene            complement(10001..12865)
                     /locus_tag="KME82_RS22810"
                     /old_locus_tag="KME82_22810"
     CDS             complement(10001..12865)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="KME82_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22810"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_215496049.1"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-77, bitscore:
                     257.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-32, bitscore:
                     111.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESRIHEGFGPIIDHFTAAARDTFDTRLAALPAGLDAAESELIR
                     AALAQALYENARLKLNRVLLLELHAAKLGGELTAEDEPGRFAQFVAKALSPEFAEQLRH
                     RYPPLRERLQRALDQQCAAIETLVARLIADRAALAEFLGKAPGRLIKLSLGQGDLHEGG
                     QTVARLTFEAGQVMYKPRSLRIDAVFDSFLAQLFEEEQRIRVPAVLDRGDYGWAAFIDH
                     RYCDGDDELRRFYRGLGHWLAMLRLLGGTDIHLENLVAAGPVPVVVDVESLFAAARPVA
                     SSNYGQAYDLAQTLIQDSVLRTGIVPFRSRSVGFGRADLSAAGSLPGEQPQLQVPVIAD
                     DGTTAARVELVEADMDRSQNHPSPNPDVSRYWDEITEAFLDASQRLRRLDADGRLAPLL
                     AAFEGCRARDVRRTTQVYVEIGRMLWHPASLHEEAKAIERARVLFSSAGGGAQPSPEDI
                     AGEIHALRYGDIPIFVLWLSPERIAATLANWRAMRIELEEMTIRSSLVVTQLNSGVDGP
                     NQRDSRSHYARRPHRDELDGRRRRLAAETMQRLLQLAVRGEDGSVTWITPESFGSQGWH
                     VQPLGADAYFGLGGVAVTLAGYRHEVAHGRADPVAGVDEALEGALLALQTFVAAQAPAT
                     VGGFTGDGSRIWAWLVLHDLLGRPQLLANACACAAALEQKGFEDDPSLDITDGSGGAIA
                     PLLGLAEATGDPRWLSLAARAASHLESQVRVDEQGTYWLTAGIADPIGGFAHGGYGIGW
                     ALERLAQSDAGSESDRQRWNALADGAFAFQDSLFDAAVGNWRDVRMKDTVNFPTWCNGG
                     VGIGLAAADLYARGGDPRDLRDLRRAVAASRGQWGFTHTLCHGDFSLWELLVRASALDP
                     EGSAVDFDEATAEVVSAIEEHGIVGGITRQAFTPGLMTGLAGAIHALNRMHPDCDLASP
                     LLLECRRSSSRVGAEALELSSLLG"
     misc_feature    complement(10007..10009)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12982..13167)
                     /locus_tag="KME82_RS22815"
                     /old_locus_tag="KME82_22815"
     CDS             complement(12982..13167)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040361.3"
                     /locus_tag="KME82_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22815"
                     /product="DUF6229 family protein"
                     /protein_id="WP_056106709.1"
                     /transl_table=11
                     /translation="MQSNDIVSAWLTGANNVGGYKNPAGPLYIEGEIAMDEAMKTPLTH
                     STSISTCPSGRCYCCM"
     misc_feature    13326..13340
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(13434..13443)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            complement(13516..14820)
                     /locus_tag="KME82_RS22820"
                     /old_locus_tag="KME82_22820"
     CDS             complement(13516..14820)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="KME82_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22820"
                     /product="MFS transporter"
                     /protein_id="WP_215496050.1"
                     /transl_table=11
                     /translation="MVVQLDITIVNLALPTLANELATDIPGLQWVVDAYTLLFASLLLS
                     AGAVSDRFGAKRSFLIGLSGFLLASAACGLAQNLTQLVAARAVQGLFAALMVPSSLALL
                     NHAFAHDPKRRARAMALWTASGAAAAAMGLLLGGVLLQTLGWRSVFFVNLPLCALGIVL
                     AWRIAETPRNADRRLDVAGQALTIAGLGGLIGAIIEMPRLGFAHGLVLGGFGLAVVCAV
                     AFAGVQSRAAQPMLPLTLFRLPNFSIALLSAIAISLAYYGLIFVMSLYLQQVAGYTPLQ
                     AGLAYVPLTVAFIAANLLSGRWLARHGVRVAIVAGLVLCASGFAWLGRLGHGESYVWIL
                     PAFLAIPAGMGLAMPATTTMILASVERSWSGTAAAVLNAVRQTGAALGVALCGLLLADA
                     GRIDVGLRTVCLVCMVGLLFSAALSWRCIRDGGSA"
     CDS             14819..14941
                     /gene="allorf_5478665_5478787"
                     /locus_tag="allorf_5478665_5478787"
                     /protein_id="allorf_5478665_5478787"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNPKQAASSVTRRRRSEDRGGAGDGSGIWFLSAGWQGIGC"
     CDS_motif       14819..14884
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNPKQAASSVTRRRRSEDRGGA"
                     /locus_tag="allorf_5478665_5478787_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14885..14941
                     /prepeptide="core"
                     /locus_tag="allorf_5478665_5478787_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1774.9"
                     /monoisotopic_mass="1773.8"
                     /core_sequence="GDGSGIWFLSAGWQGIGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNPKQAASSVTRRRRSEDRGGA"
                     /leader_location="[14818:14884](+)"
                     /alternative_weights="1793.0"
     gene            complement(14977..15474)
                     /locus_tag="KME82_RS22825"
                     /old_locus_tag="KME82_22825"
     CDS             complement(14977..15474)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025892.4"
                     /locus_tag="KME82_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22825"
                     /product="DUF4442 domain-containing protein"
                     /protein_id="WP_215496051.1"
                     /transl_table=11
                     /translation="MSDLSGSLDRLAFLPPSWRYRIVSAALGRQSRYFRTHGFRIVHIE
                     AGKVSIAAGNRRGLRNRAGGIHSMAASLAGEYAAALVVAQHLACSAKLVVRRVQADFRK
                     PLCGDIQAHASLDPAQVGAVSGACDGQLRVAMQVVDASGKVPIRGHVDVVWRSPMRAHD
                     VS"
     misc_feature    15482..15495
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(15497..16876)
                     /locus_tag="KME82_RS22830"
                     /old_locus_tag="KME82_22830"
     CDS             complement(15497..16876)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="KME82_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22830"
                     /product="phosphotransferase family protein"
                     /protein_id="WP_215496052.1"
                     /sec_met_domain="APH (E-value: 4.3e-31, bitscore: 106.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGGEFCAEHSTAEEVAQGRAMANDQDDGETDGASAYDASSRIAA
                     SSDAGGLSNARQRFAQVASIDSQARARHPFADSDHGIRRQISTAGISIRRRTMAEPRTC
                     TDMPVQRSDDPLLSESSAAAVAVTDWLRSQGVDVGGRPDIRRCDGGMSHLTYRLRYDSH
                     DLVLRRPLPGQGGLQRMRREFALQAALRPHYPVADMVRLCVDQGIVGTPFYVMRYVPGL
                     VPRRRSFAGVALSANDARQVCINLLDKMLALHRIDPRSLASKELVLAPSSASHLRKRLL
                     HWLSRHARLKAWTICDLRPIGQWLIDRVPEQRHAALLHNDWRLDNIVFDAAQPARIRAV
                     LDWEFAGVGDPLMDLGILLSYWIDPGDNFVVRRYQWQPSHLPGMLSRDELLDRYLSASA
                     RDTRDWAFYRIFGLFRYLLTLQELYVRHVVQGGEEKAFFSGIWVLMHYLNWKCRGLMRH
                     A"
     gene            17036..18037
                     /locus_tag="KME82_RS26720"
     CDS             17036..18037
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KME82_RS26720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_252255485.1"
                     /transl_table=11
                     /translation="MRDRLYKSGRYRADAVRFPCRRAATCKLRDRSGNRTALYAKVRRP
                     LLATQFPQAQDARHRDRLTCRFRLEPATPPTSTPGTAGKTANCLDPVTALACNPRNGSR
                     AGRRAMTSFRNRVAHQARSASRDMRRYLACLALLPAAWSMAANAQDPQWRTVSDEDGIR
                     LETRRIAGERFDELRITTSLKASPEAVADYLFGKYLDEKNKNIRRTFIERGRELTVWSD
                     VLSTPVTSERCYSMRFERHALANQAIRVKFTSLDYVGRKPTADCIALRSRGEWVLTPAG
                     TGTRLTYASLTDIGGNVPAMLVRRSLSSAAISSVRKVAAGSSGLALPRGLGD"
     misc_feature    18517..18535
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.28"
                     /tool="antismash"
     misc_feature    complement(18743..18757)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    19058..19069
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.78"
                     /tool="antismash"
     CDS             complement(19127..19213)
                     /gene="allorf_5482973_5483059"
                     /locus_tag="allorf_5482973_5483059"
                     /protein_id="allorf_5482973_5483059"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLHRNSSPGSCDGYAGTSCMPRKCRGAI"
     CDS_motif       complement(19184..19213)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLHRNSSPGS"
                     /locus_tag="allorf_5482973_5483059_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19127..19183)
                     /prepeptide="core"
                     /locus_tag="allorf_5482973_5483059_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="1853.2"
                     /monoisotopic_mass="1851.8"
                     /core_sequence="CDGYAGTSCMPRKCRGAI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLHRNSSPGS"
                     /leader_location="[19183:19213](-)"
     misc_feature    19168..19184
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.0"
                     /tool="antismash"
     gene            19205..22273
                     /locus_tag="KME82_RS22840"
                     /old_locus_tag="KME82_22840"
     CDS             19205..22273
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017354585.1"
                     /locus_tag="KME82_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_22840"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_215496054.1"
                     /transl_table=11
                     /translation="MKQTRVAPRHTLLASALLLVLGQPVYAQTTTPTPGTAADAQPKPD
                     AERDARTLDTVVVTGIKGSLTSSMNLKRDAQGVVDGIAAEDIGKFPDTNLAEALQRISG
                     VSIDRSNGEGSRVTVRGVGPDFNLVLLNGRQMPTATGGRAFEFSDLAAESISAVEVYKT
                     SRAATPTGGIGATINIKTARPLDNPGLHANAGIKGIWDGSDDDLPGDYKGSSVTPDASG
                     IFSNTSADGRFGIALSANYLKRESGSASAFVASGNGWRPFIDTPQPNGEGAGSALPLPG
                     QPGSGNITNRPGPNDVYSMPQSLGYSINSVKRERLNSQLTFQWAPTDNLTATLDYTYSQ
                     NKIEQLRNDMSVWLNFTPGTSSWTKGSGSSPTYYDERYNGNSDFANGASKTAVKRENKS
                     VGLNVDWRVADNFKLNLDYHRSTADSSPDSPYGSSNTLGAAGFFRAGNTIDFSRDFPVL
                     TLHLPAGMTAIDPAQMLVAGSVFRNDMHRAEIEQFQANGEFEFQNYSKLNFGVASTDYE
                     NRSAFTNVQLDTWGGATSVNDYPDSVWQLQHMGDFFNGASGSRDPKFTDSFFLFDFDQV
                     RQLAEDAWVAAGKGSREDYRASFDYSGAAVPGSTANRTVGDSQVREKSSSFYLQWSNTF
                     EWKLPVNLAAGVRYERTKVKASALQPAPSGIDWLSENEFIIRYSGSQFRNLDGDYKYWL
                     PSLDVSVDLTDSMKLRASYGESIGRPNWGSLNPALSVGGQARYDGGGGGAGNPGLKPLE
                     SRNFDLSYEWYYGESSYFSVGYFRKKIDNFIADQVSRQTPYPDLHTPAGGAYWNQAIAQ
                     GCAATDRPCIRNYILNTYNGQPGVVKTGVDANGIATGTITGQPGDPVLAFNITAPVNNR
                     ADTLDGWEFNLQHVFGDSGFGLAANYTIVNSGLTYDDGRLGTQFAMTGLSDSANLVAFY
                     EKGPWQARAAYNWRDKFLTSLGDGKGANPIYVEAYGQLDMNVSYAVTDNLVLSLEGINI
                     TDETMRTHGRNTRQLYSYDQSGPRYMFGVRYKF"
     misc_feature    19211..19224
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.52"
                     /tool="antismash"
ORIGIN
        1 acggaaccct ggcgccgggc aagccgaacc atcatcacct cagcggtctc gacggcgcct
       61 ggacgcaagg acacttcgtc accggccgcc tggagcagtc gggatggggc gccgacatgg
      121 gctatccggc cttgcgttgg tccgaatcgg gcgaggcgat cgaagtccag ttgttcgcat
      181 ccgacgacct gcccttgcac tggccgcgac tggatgcgtt cgaaggcgac gagtacctgc
      241 gcatcctggt accggtgcat gcgccggacg gctcggtcac ggtggccaat gtgtatgccg
      301 caaggcccga ccggcaagcg tgatcgccac cgtgaaggcc gaggtatttt cgtaaccgtc
      361 cgcattgcga agcagcggcg acttgcaccg cggggattgc gttgccccgc tcttgatcgg
      421 gtccgagaat gcccgcggtg ccccggaata gagcgctacc gacggcatcg cacgcctggg
      481 ccgtcattgt cgaaggccca atgggttcca tcgaagcacg atcaagacca caaggagcaa
      541 ggaatgctga aacaaaagga tgcactcgga aagtttctcg ccgtggcgat ctgcctgagc
      601 ggattttcgg cggtcgcgca cgacgccgtc gcgggcggct gggtcgaaag cggccgcacc
      661 gcctactaca agaacagttt cttcggcagc ttcgacagcc acacctgcag cgtcggcggc
      721 ccggatttcg ccggtttccc gggatcgtgc ccgaacgacg gcgcgagcgg ctggaacagc
      781 aacttcaccg cctcgttcga cctgtcgagc agcgatctca acatctgcaa cttcgacccg
      841 cactcccccg gctcctcgtg cgacacccag gcgtatgcgg tcaacggcca ggccgtccgc
      901 ggcggccttc cggccaactg cacggtcggc acgcgcgcgg tggcctcatg gggacgcaag
      961 gagacgatcg tcatccagta cgaagaactg gatgtcgaaa cgaccgagca agcgcgagag
     1021 tatgtctgcc aataaggcga cgatattttc gtaacgcgca cacatctccc gggccgcgtt
     1081 cgcgtggtcc gggagaaccg gagcagtcgg acagggcgcc ttgttgggac cgatcgccgc
     1141 gtataagctc gccacgccac gccacgacgc ctggcatcga cgaacgtcgc cgcatccctc
     1201 tcccccttga gagcacctca tgactcgcac tcctgtgtcc gccttggccg ccgcgctcgt
     1261 cgccggcgcg ttgctgtccg catgttcgca acccaagtcc gccgcgaccg acacgcccgc
     1321 ggcgactacg cccgctgcgt ccgcgcctgc gccccctgcg ccgcagccgg cgaacgccga
     1381 tgtgttccga ttcaaaatcg gcgcgctcga tgcgatggca ctgaaagacg gcgacatcga
     1441 cgccgccaac gacggcaaga ccttcgccgt cggccagccg gtcgatgcgg tgaacgcgct
     1501 gctgaccgcc gcgggccaac cgaccgatac cttgcacctg agcattcaac cgctgctggt
     1561 ccgcagcggc gcacaggtcc tgctgttcga taccggcgcc ggcgatgcct cgttcgcgcg
     1621 cgccggacgc ctgccggcgt cgctgcgcgc ggccggcgtc gagccctcgc aggtcaccga
     1681 catcttcctc tcgcatcacc atcccgatca cgtcggcggc ctgctggaca aggacggcac
     1741 gctcgccttc gccaacgcca agatccatct gtcggcgccc gagtgggagg tgatgaagaa
     1801 cgacaaggcc gccgccgcgc tggtcgccgc gatcgcgccg aaggtcgaaa ccttccagcc
     1861 cggcgcggcg atcgttcccg gcgtggtgac cgcggtcgcg gtcgacggac acaccccggg
     1921 ccacagcgcc tacgaaatcg cctcgggcga tcagcgcctg ctctacatcg gcgacagcgc
     1981 gcatcactcg gtgatctcgg tgcagcgccc ggagtggacc gtgcagttcg acgagaacgc
     2041 accgctggcc cagaccagcc ggcgcgcgct gatgcaacgc gccgccgacg gcaagctgcg
     2101 cgtgtacgcc gtgcatttcc cgttccccgg cctgggccag ttcaaggccc agggcgacag
     2161 cttcgtgtgg gagcccgaac gctgagccat tgatctggca acgaagcgat agtcgtatca
     2221 accgcagcga gcggatttcg atggcgaaat ccgctcgctg cctgcgtctg gggccaacgc
     2281 ggtttatcgc cctggcgcga gccgcgcttg gacttgcacc gccgcggcgt taagttaaag
     2341 caggcctgcc ccaaggagcc atcgatgcag actgcgacgc cgcaaccggt ggtttcccgg
     2401 ctgacccggg ccgccatctt cctggtcgtg accctgaaac cgggcgccga gcacgaaacg
     2461 caggtgcgcg ccctgtgcgc cgatctggcc tcgctgctgc gcgcggtcgg ctttcgcgat
     2521 ctcgaaggcg gcctgtcgtg cgtcatggcc ttcggatcgg atgcctggga tcgcctgttc
     2581 ggcccgatcc ggcccaggga actgcatccg tttcgcgaaa tcgtcggtcg ccatcgcgcg
     2641 gtgtccacgc cgggcgacgt gctgctgcat atccgggcgg cgcgcatgga cctgtgcttc
     2701 gaactcgcga ccgaaatcat gtcgagaatc ggcggcgccg tggcgagcgc ggacgaggtg
     2761 catggcttca agtacttcga cgatcgcgac ctgatcggtt tcgtcgacgg caccgaaaat
     2821 ccggtcgata cagccgccgc cgacgcggcg atcgtcgccg gcgaagaccc gcagttcgtc
     2881 ggcggcagct atgtgatcgt gcagaagtac ctgcacgatc tcgcggcctg gaacacgctg
     2941 ccggtcgaac ggcaggaagc catcgtcggc cggcgcaagc tgtcgaacat cgaactcgac
     3001 gacgcggcca aggctccgta cgcgcacaac gtgctgacca gcatcagcga gaacggcgag
     3061 gagctgaaga tcgtccgcga caacatgccg ttcggcagcg tcggccaggg cgaattcggg
     3121 acttacttca tcggctacgc gcgttcgccg acccggatcg aacgcatgct cgagaacatg
     3181 ttcatcggcg atcctcccgg caattacgat cgcctgctgg acttcagcac ggcggtgacc
     3241 ggcagcctgt tcttcgcgcc gtcggcgacg ttcctggacg gtgtcgaggc cgaggccgct
     3301 gcgccaaaag gcgcggcgga ccacggccac gaccggagca tcggaccatg aacagcccct
     3361 acgaaacgct gggcgtggcg ccgaccgcgt cgctcgacga gatcaagagc gcctaccgcc
     3421 gcctggccag gaaactgcat ccggacctca atccgggcga caagtccggc gaggaacgct
     3481 tcaaggacgt cggcaacgcc taccgcctgc tcagcgatcc tgacaagcgc gcgcgcttcg
     3541 atgcaggaga aatcgacgcc gacggcgccg agcgtccgca gccgcgttac taccgcgatt
     3601 acgccgacgc cgaaccggcc ggcagctacg cgaacgacgc cggcttcgcc gatttcgccg
     3661 acggcgacga cccgttcgcc gaactcctgc gccggcaggc gcgcgcgcgg gccaaccggc
     3721 gcggccagga cctgcactat cggttgcaga tcgcgttagc cgaatcgatc gacgccggca
     3781 ccaggcgatt gacgatgccc gacggcagca ccatcgacgt gaccattccg gccggcgtcg
     3841 tcgacggaca gatcctgcgg ctcaagggca agggcgcggc gagcgcgggg caaggcggtc
     3901 ccggcgatgc gctggtcgag atcgaagtcc tcgccgatcc gcgcttcagc cgcgatggcg
     3961 acgatctcac cctggaattg ccggtctcgc tgaccgaggc ggtgctcggc gatcgcgtcc
     4021 gggtgcccac gccgaccggc gaggtgacga tgacgatccc acccggatcc aacagcggca
     4081 ccaccctgcg cctgaaaggc atgggcgcgc cgcgtcgcgg cggcggacgc ggcgaccagt
     4141 acgtgcggct gacgatcgtg ttgcccaagg gcggcgatcc ggagctgacc gaattcgttt
     4201 cgcagtggag cgccggcaag gcgttcgacc ctcgcgggga ggccaaggca tgaacaccat
     4261 cgacatgacg cagttcctca acgaatcgac catcgagctg cacacgctgg agcgttggat
     4321 cgaacagcgc tggatcatcc cgtcgcaggg caccgcgcgc gtggaaattt cggaaaccga
     4381 tgcggcgcgg gcgattttca tccgcgatct caccggcgat ctcggcgtca acgaagaagg
     4441 cgtggcggtg gtgctgcatc tggtcgatca gttgcacggc ctgcgtcgcg cgctgaccga
     4501 attgcggatc gagatgaatg catcgcgagg cgacccgggc cacgagtccg actgagcggt
     4561 atccggcacg tcggtgggcc ggcgttgccc atgaacctgg cgccaacacg cgcgatcggc
     4621 cccggctcca gccatcctcc cagtcatgtc tccggcctgg ccgctgaacg gctacggcgc
     4681 ggtcccgttg acgacggtct ttgaggctaa gctctggcca cgacgcgcgg gcggctgccg
     4741 tgcagtcgcc gttcctgccc cgatgcacta cgacgaggtg cctgcgatga aatccctgaa
     4801 acgttccgcc cagtgcctga tgctcggcct gaccttgtcc atggccttgt cggcgcaggc
     4861 ccagaccgtc ggctacaaca tccgcaccgg cgatgtctgg gtcgatacgc ggctgggcga
     4921 gatcaacgat tacgggcggc gttaccctga gcccttcgtc gatgaagtca gcggctatta
     4981 cggtgcgccg cggccgtatg tcgaagagct gctgcaacgc cggcgctggg cgccgggcga
     5041 tgtctactac gcctgcgcgc tcgcgcattc gctcggcgtg ccgtgccaga acgtcgtgcg
     5101 cgagtacgac cgcaaccccg gacaaggttg gggcgcggtc gccaaacgca tgggcatcaa
     5161 gcccgggtcg cccgcgttcc atgcgctcaa gcgcggcgcg gtgacgactt acgaccgttg
     5221 gggctatccg atccgcgtcg atcaatccgt gcatgtgaac tgggccgatc atgggcccgg
     5281 caaggggcac ggcaagtcga aaggtcccga tcaccggtcg tacgactccg gccattcgta
     5341 tccgcaaggc cacggcaagg gaaaaggccc caagggcggc gattcgcacg ggaacggcaa
     5401 gggccacggc aaagacaagg acaagggcca tggcaacggc aacggcaagg gtaacggcaa
     5461 gggccatgaa cactgagcca tcgggggccg ggtagacgac ggtccgtccg tcttgaccca
     5521 gccgaaccgc agcgcggctt cggttgggtc gagtggccgg cgttcaatgg cgctttcgga
     5581 tcggcgccac ttctcggtcc agggcgcgac gacttgcctg tcgtgcgcgg ccgaaatcag
     5641 cggcgctcat cgcaccgcgc cgacgctctc cgtgtgcatc catgtcccgc tgtggttcga
     5701 tgctgcaagc gtcaaccgat ccgagcgaca accaccacga agcgcgcgac cttgcatcgc
     5761 ctcacttgcg gccgtgtccg tccgaaaccc ggccgcgctt cggaaaggac ttgtcggtca
     5821 gacaggcatt gagccacccc tgatcggcgc gcaggccggg aagcgccagc cagtcgtcgt
     5881 catcgctcaa tacggcgata tccggatcga gcttgttcaa cgggccgaag ctttcgacga
     5941 tgtcggcctg ctccggagtg ggatcgaagt tccagcccgc ggcctgtccg gtgacggaca
     6001 caccggggca ttggctgtcg acgcaggcgg cgatcacacg cggctttccg cccacgacat
     6061 cggcgacggc ccgctgcatc accacgtaat ggctggcgaa atcctcgctg acgctgcaga
     6121 tgcgatcgcc gttctgcacg ttcatcacgc cgaagcagtt gtacgaatag acagcgcggt
     6181 cctgccgatc cgggatgaac gcgcagttgg cgcggtagcc cgcgaacgaa ccgccgctgt
     6241 aggccgcgac gcgcgcgcgt tgcttcatcg catcggcgat gagcttcggc gttccgccga
     6301 cacgctcgct caggtacttc gtgcgctgtg ccgtggcatc gagcaggatc gcgcgttgct
     6361 cgtcggcgtt cggcgcgtcc tcgccctcac cgagcccgcc gagatccttc tcgcgcgcgg
     6421 cgatccagcg gcgctggctg ttgatcaagg ccgcgcgcac ctccggatcc gtggcgagac
     6481 ccagcagatc gaaataagcc ttgcccatcg cggcatcggc cttgcgcaaa cccgggtccg
     6541 cgcacagcct gtgttcaagt ccagtcgacg ctttgcggca gtccaaagca tgggccggcc
     6601 cgccgagcaa ggccgcggac atcaggcaaa tggtcgaaag ccaaatcttc acgggttgct
     6661 tgtccttggt ctatgactca gcatacccaa tgaacgcgtg gccgagcagc ccgcggaccc
     6721 gagttcggca aacgcatcgt gtcgtcgccg gcccggaacc ggcgaacgcc ggctagttca
     6781 cccttcgcag gcgccgatag aaaccgccat cgggcgtgct gccttcgatg atcaattcat
     6841 cgccgaccag cttgatcggc cgtggctgat cggtgccggt gtagctcggc atcaggctgc
     6901 cttgcacctg atggatcacc cggccctgcg cttcatcgac tcggtaggta ccgaagtacg
     6961 cgacataacc gtcgtaggcg gcccggactt cgcgctcgct gcccttctgg tcgcccgcgg
     7021 caaacggcgg cgtcgcgggc gtgcgcatga cctgcacatg catatgcccg gtcgcgtcgt
     7081 acacgatgta tccggtcggg tgctcgccat acggatgtcg ggtcgtaccg gcggcatcgg
     7141 tgtcgaccat ctccacgacc tgccacgtgc ctaccagacg ggagctcagc gagcccgcgc
     7201 cgtccttcgc cgcgttcgca gccgcggtgg cgcagccgat cgacaggctc gccgctatcg
     7261 aaacgaagat gccggctttc acggagtcct ccattgatcg taaagaaaca tttcgagcga
     7321 accgcctgca tcggggttcg acacctgcgg cagcagtgtc ggcgtcgcaa gacggacaag
     7381 cacctgtatc gcttgtccga gccggatgtc gacgaagccg acaagatcgc cacccgccag
     7441 gcgtaacgca agccgcatat gtcatatctg gcgcatgacg gatcggtggc ggcttcgcct
     7501 atgcgccctt gcctgcatcg gccggcaaga acgtcgggca ttcaaacttg aatgaacaat
     7561 cccacgcctg gtccagcgag cgacaggatc ggcgcgcccc gcctcaatcg ttcggtgccg
     7621 ccgccggatg cagatgaatc gccagccaga cggcgccctg cgaaacccgc cgcacggtgt
     7681 ggggcgtgcc tgcgggcaag aagacataac cgccgcaaac cagttccatc gattcacccg
     7741 caacctccaa ggttgcctcg ccttgcagca acgcgaccca ctcgtcctgg gtctgcacgt
     7801 actccaccgg aatcgtcgca gccgaactga cgatccgctc gacgacgagg ttgttgtgcg
     7861 tgagcaaagt ctcgaagcgt tcgccctggg cgggcgcatc ggcatcgacg aacaggtttc
     7921 cggtcgacat gcgggcgatc ctctttcaaa tatagccgac ccggaaattg aatcgtcccg
     7981 ccgatacaag tcggccattc aacgcgcgcg gcaaacactc cgcctcaatg ataccggctc
     8041 gattcgcatc gctcatcaaa aaaaggacac tctgatcaaa cgcgaagatg accagcaaac
     8101 ctgtcgcaaa cttcggcgca ggtgatccaa gtcgcctggg caatgggctc ttggcttgag
     8161 tcagccccag cacggtgcgc actcacatcg agagcgtatt tcgaaagctc gagtgctcca
     8221 ctcgcgcggc cgctaccttg aaggcggctc agttgggctt gctttagcgt ccacatggat
     8281 attgcgcacg gctgagccgt cggatgccgc ttctagaatg ggttgtacgc aacccaaccc
     8341 ttgaaggtga acgcggcata gaacagttcg acatgctcga acccggcttc gcgcagcagc
     8401 gcctcgtcgt gttcgggcga gagcatgggc agtcggctgt cgagcgcggc gaccgatttg
     8461 ctcgcgttct ccgcaggaat gccgccggac gccaccgcga acgcggcata gcgctggagc
     8521 cagcgcaatt tcccatcgtc gggaacgctg tggtgagcca cgatcaaggg cgctccgggc
     8581 ttcagtcgtc gcctgagttc gatcagcgtc cgcaggcgct cgtcggcggg caagaagtgc
     8641 aaggtcaaca gacaggtcgc gccgtcgaac gggccgtccg gtgcggtgtc gatgtagccc
     8701 tcgcacagct ccacacgcga cgcgagcggg cccaaggtgt cattcgccag tttcaacatc
     8761 tcggccgacg ggtccacgcc gacaaaacgc cattcgggct gcgcctcggc gaaaaccttc
     8821 aattccaggc cgccgccagc gccgagcacg agcacccgac cgtcgtgcgc aacggcctcg
     8881 gccagcaaca gcatcgtcat ctgctgcagg gcatggaaac ccggaacctg ccggaccggg
     8941 ccttgcgcgt agcgggcaac cgcctgggga tctgagaacg acaaagcacg gctccacttg
     9001 gggactcgac accgctgatg ctaacgcaga gcgtttgcgc ccgatcgatc gcggatgctt
     9061 cgatgcgttc catggatgcg tcgccttggg cgatcacgcg gccaacggcc cataatgccg
     9121 cgggcgatgc gctgcaagcg gacacactgt ttcgtcactg atcgccacca ccccagaaag
     9181 atccacatgc ccacaaaagc aagaccccgg cggatgacga ttggagcggc tacgtacgtg
     9241 tggatcgttc gctccatcga tcccaaccat atcgtcctga gagcctggtc cagggaacga
     9301 gggcgcaagg atttcccgct cgaagtgcgc atgcgcttcg acgatccgtg gctgaactat
     9361 ggcccgatca tcaccgcgcc cagcgaacgg cgccacgaat ttttcgaact ggcccccgtc
     9421 acgccaaaaa cggtgcgctg ggcgatcgat gccgcgatcg cggcaggctg gaatccgcac
     9481 aaaccccgcg agcatcgcct gttcgaacga ggatcgaacg gcgatctggt gagcgtgcga
     9541 agctcctgaa gcgctttgac gtttctgggc cgatgctcgg ctctcacgct ggtgaacagg
     9601 accgaaagtt cacggccatc tagcatccgc taccgagcga gaacggacgc ctacgaaaac
     9661 gccggcgcat ccatgcccgt catcggcgcg ctcccataga gagatcatgg ggctctaggc
     9721 tgaagtcagg tttcatttcc agcgctgcga ggcttgcaac tcgcgttagc aacatcacac
     9781 ccggagggca gcgctcatgg atgtgcgccg tgcgccaccg ggacaggatg tcccgtgtgg
     9841 cgcatgcccg cgtaagcgcc gcacgcgcgg gcactcgatc cacaaaaaaa cgtttttctt
     9901 tggttacctt ttgaccgaag ggaatccaga cagaattttt tcgctttaga caaaagaaag
     9961 taactcggcc gcttgcggac gaaagccgtt gatcttgccc tcagcctaat aggctcgaga
    10021 gctccaaagc ttccgcacct acgcgagaag agctccgccg acattcaagc aacaacggcg
    10081 aggcgaggtc gcaatcagga tgcatccgat tcaaggcgtg aatcgcacca gccagtccgg
    10141 tcatcaggcc aggcgtaaac gcctgacggg tgatcccccc gacgataccg tgctcctcga
    10201 tcgccgaaac cacttcggca gtcgcctcat caaagtcgac agccgaaccc tccggatcga
    10261 gcgccgacgc acgcaccagc agttcccaca gcgagaaatc gccgtgacag agcgtatggg
    10321 tgaaccccca ctgcccgcgc gacgccgcca ccgcgcgacg caggtcgcgc agatcgcgcg
    10381 gatcgccgcc gcgtgcatac agatcggccg cggccagacc gatgccgacc ccaccgttgc
    10441 accaggtcgg gaagttcacc gtgtccttca tgcgcacatc gcgccagttg ccgaccgccg
    10501 cgtcgaacag cgagtcctgg aaggcgaagg cgccatcggc caacgcgttc cagcgttgcc
    10561 ggtcgctctc gctgccggca tcggattgcg ccagacgctc caaggcccag ccgatgccgt
    10621 agccgccgtg ggcgaaaccg ccgatcggat cggcgatccc cgccgtcagc cagtaggtgc
    10681 cttgttcgtc gacccgcacc tgcgattcca gatgcgacgc cgcgcgcgcg gcgagcgaca
    10741 gccaacgcgg atcgccggtc gcctcggcga gccccagcaa cggcgcgatg gcgccgccgc
    10801 tgccatcggt gatgtcgaga ctcggatcgt cctcgaaacc tttttgctcc agcgccgccg
    10861 cgcacgcgca agcgttggcg agcaattgcg gccgccccag cagatcgtgc agcaccagcc
    10921 aagcccagat gcggctgccg tcgccggtga agccgcccac cgtcgccggc gcctgcgccg
    10981 cgacgaaggt ctgcaaggcg agcaaggcgc cctcgagcgc ttcgtcgacg cccgcgaccg
    11041 gatcggcgcg tccgtgcgcg acttcatgcc gataaccggc caaggtcacg gccacgccgc
    11101 cgaggccgaa atacgcgtcg gcgcccaacg gctgcacatg ccagccctgg ctgccgaagc
    11161 tttccggcgt gatccaggtg accgagccgt cttcgccgcg cacggcgagc tgcaacagac
    11221 gctgcatcgt ttcggcggcc agccggcgcc tgcgcccgtc gagctcgtcc cgatgcggac
    11281 ggcgagcgta gtgcgagcgg ctgtcacgct ggttcggccc atcgacgccg ctgttgagct
    11341 gggtgacgac cagcgaactg cggatcgtca tttcttcgag ttcgatccgc atcgcgcgcc
    11401 agttggcgag cgttgcggcg atgcgctcgg gcgacagcca cagcacgaag atcggaatgt
    11461 cgccgtagcg cagcgcgtgg atttcgccgg cgatgtcctc cggcgacggc tgcgcgccgc
    11521 caccggcgct ggagaacaag acgcgggcgc gctcgatcgc cttggcttct tcgtgcagcg
    11581 acgccggatg ccagagcatg cggccgattt ccacgtagac ctgggtggtg cggcgcacgt
    11641 cgcgcgcgcg gcaaccttcg aacgcggcca gcaacggcgc gagccgaccg tctgcgtcga
    11701 gtcgccgcag tcgctgcgag gcatcgagaa aggcctcggt gatttcgtcc caatagcgcg
    11761 acacatccgg attcgggctg ggatggttct gcgagcggtc catgtccgct tcgaccagtt
    11821 ccacccgcgc ggcggtggtg ccgtcgtcgg cgatgaccgg gacttgcagt tgcggctgtt
    11881 cgcccggcaa cgaaccggcc gcggacaagt ccgcgcggcc gaaacccacg ctgcgcgaac
    11941 ggaacggcac gatgccggta cgcagcaccg agtcttggat tagcgtctgg gcaagatcgt
    12001 aggcttgtcc gtaattcgat gacgcgaccg gccgagccgc cgcgaacagg ctctcgacat
    12061 cgaccacgac cggcaccgga ccggcggcca ccagattctc cagatggatg tcggtaccgc
    12121 cgagcagacg cagcatcgcc agccaatggc cgaggccgcg atagaagcga cgcagttcgt
    12181 cgtcgccgtc gcaatagcga tggtcgatga aggcggccca gccgtaatcg ccgcgatcga
    12241 gcaccgcggg cacgcggatg cgctgttctt cttcgaacaa ctgggcgaga aacgaatcga
    12301 acaccgcatc gatgcgcagc gagcgcggct tgtacatcac ctgcccggct tcgaaggtga
    12361 gccgggccac ggtctgtccg ccttcgtgca ggtcgccctg gccgaggctg agcttgatca
    12421 ggcgaccggg cgctttgccg aggaactcgg ccagcgccgc gcgatcggcg atcaggcgcg
    12481 ccaccagggt ttcgatcgcc gcgcattgct ggtcgagcgc acgctgcaag cgctcgcgca
    12541 gcggcggata gcgatgccgc aactgctcgg cgaattccgg gctgagcgcc ttggcgacga
    12601 actgggcgaa gcggccgggt tcgtcttcgg cggtgagttc gccgccgagc ttcgccgcgt
    12661 gcagttcgag cagcagcacg cggttgagct tgagccgcgc gttttcgtac aaggcctgcg
    12721 cgagcgccgc gcggatcagt tccgattcgg cggcatcgag gccggcgggc aaggccgcaa
    12781 ggcgggtgtc gaacgtgtcg cgcgcggcgg cggtgaaatg atcgatgatc ggaccgaagc
    12841 cctcgtggat acggctttcg gtcattgcgc caccgggctg agatttggga gagcgggccg
    12901 tcggcccatg agcagtacgc aatcagtgcc gagacgacgc gcaacccggc tgggctgcgc
    12961 gccgacgacc tcgggaacgg cttacatgca gcagtagcag cgaccgctcg ggcaggtcga
    13021 gatcgaagtg gagtgggtca acggggtctt catcgcctcg tccatcgcga tctcgccttc
    13081 gatgtagagc ggtcccgccg gattcttgta accgccgacg ttgttggcgc cggtgagcca
    13141 ggcggagacg atatcgttgc tttgcattgc agatcctcct tgagtactga atgtcgtcca
    13201 gcagacggcg gctgcgtgtg gcgaaactcc gtcgcaccgg acatcgattt cgagccttgc
    13261 ggcctctcat cgcgaaccga attgactcgg tgacgtacat caagagatac cgcctcggca
    13321 ctctaaacag ccatgtcgat aactgtcaaa tgagtgctgc gaacgacttt tggtcacgct
    13381 gtattcgctt cgagcgatcg atcggcggcg gccccacggc ttcgatgaag gcatcgaaaa
    13441 acacttcgtc ggcgataccc gcatcgcccg caagcgccgc acaaagccgc cgatagtgac
    13501 ccaaagtttg ccggctcagg ccgaaccgcc gtcacggata caacgccacg acaaagccgc
    13561 cgaaaacaac agcccgacca tgcaaacaag gcatacggtc cgcaggccga catcgatgcg
    13621 tccggcatcg gcaagcaaca ggccgcacaa ggccacgccc agggccgcgc cggtctggcg
    13681 caccgcattg agcaccgccg cggccgtccc cgaccaggac cgctccacac tggccaggat
    13741 catcgtcgtg gtggcgggca tggccagccc catgccggcg ggaatcgcca ggaacgcggg
    13801 caatatccag acgtagcttt cgccgtgtcc gagccggccc agccacgcga aacccgaggc
    13861 gcacagcacc aggcccgcca cgatcgcgac gcgaacgcca tggcgcgcca gccatcggcc
    13921 gctgagcaga ttggcggcga tgaaggccac ggtcagcggc acataggcca ggccggcctg
    13981 cagcggcgtg tagccggcaa cctgttgcag gtacaggctc atgacgaaga tcaggccgta
    14041 gtaggccagg ctgatcgcga tcgcggacag caacgcgata ctgaagttgg gcaatcggaa
    14101 cagcgtcagc ggcagcatcg gctgggcggc ccgcgactgc acgccagcga aagcgaccgc
    14161 gcacaccacc gccaggccga atccgccgag caccaggcca tgagcgaatc ccagccgggg
    14221 catctcgatg atcgcgccga tcaacccacc caggcccgcg atcgtcagcg cctgcccggc
    14281 aacatcaagg cgcctgtccg cgttgcgcgg cgtttccgcg atgcgccacg ccagcacgat
    14341 accgagcgcg cacaacggca ggttgacgaa gaaaacgctg cgccatccga gcgtctgcag
    14401 cagcacgccg cccagcagca aacccatcgc cgccgccgcg gcgcccgaag cggtccacaa
    14461 cgccatcgcg cgcgcgcgcc gtttcggatc gtgcgcgaac gcatgattga gcaaggccaa
    14521 cgaggacggc accatcaacg cggcgaacag cccttgaacc gcgcgcgccg ccaccagctg
    14581 ggtcaggttc tgggcgaggc cgcaggccgc cgaggccaac aggaatccgc tcagtccgat
    14641 caggaaactg cgttttgcgc cgaaccgatc gctcaccgcg ccggccgaca gcagcagcga
    14701 ggcgaacagc agggtgtagg cgtccaccac ccattgcagc ccggggatat cggtggccag
    14761 ctcgttcgcc agcgtcggca gcgccaggtt gacgatggtg atgtcgagct ggaccaccat
    14821 gaacccgaag caggccgcca gcagcgtgac gcgcaggagg cggtcggagg atcgaggcgg
    14881 cgctggcgat gggtctggca tctggttttt atcggcaggt tggcaaggga ttggttgttg
    14941 aagcttcgat cgcacggctc atgtttgcgc caacggctac gaaacatcgt gcgcgcgcat
    15001 cggcgaacgc cacaccacat ccacgtgccc gcggatcggc accttgccgc ttgcatcgac
    15061 cacctgcatc gcgacgcgca actggccgtc gcacgcaccc gatacggcgc cgacctgcgc
    15121 cggatcaagg gacgcatgcg cctggatgtc gccgcacagc ggtttgcgga aatccgcctg
    15181 cacccgcctg accaccaact tcgcgctgca ggccagatgc tgcgcgacca ccagcgcggc
    15241 ggcgtattcg ccggccaggc tggccgccat cgaatgaatg ccaccggcgc gattgcgcaa
    15301 accacgacga ttgccggccg caatcgacac cttgcccgct tcgatatgga cgatgcgaaa
    15361 gccatgcgtg cggaaatagc ggctttgcct acccagcgcg gccgatacga tccggtagcg
    15421 ccagctgggc ggaagaaacg ccaggcgatc cagcgaaccg gacagatcgc tcatgatccg
    15481 ctcgtgccag atcaggctag gcatgtcgca tcaatccgcg gcatttccag ttgaggtaat
    15541 gcatcagcac ccagatacca ctgaagaacg ctttctcctc gccgccttgc accacgtggc
    15601 ggacgtacag ttcctgcaag gtcagcaggt agcggaacaa tccgaagatc cggtagaacg
    15661 cccagtcccg ggtatcgcgc gcggacgcgc tcaggtagcg atccagaagc tcatcgcgac
    15721 tgagcatgcc gggcaggtgc gacggctgcc attgatagcg ccgcacgacg aagttgtcgc
    15781 ccggatcgat ccagtacgac agcaggatgc ccaggtccat cagcggatcg cccacgccgg
    15841 cgaactccca gtccagtacg gcgcgtatcc gcgccggctg cgccgcatcg aagacgatgt
    15901 tgtcgagccg ccaatcgttg tgcagcaagg cggcgtgccg ttgctcgggc acgcgatcga
    15961 tcaaccattg gccgatcggc cgcagatcgc agatggtcca cgccttgagc cgggcgtggc
    16021 gactcaacca gtgaagcagc cgcttgcgca gatggctcgc gctggagggc gcgagcacca
    16081 gttccttcga tgccagcgaa cgcgggtcga tccgatgcag tgcgagcatc ttgtccagca
    16141 ggttgatgca gacctgacgc gcatcattgg ccgacaaggc gacgcccgcg aacgatcgcc
    16201 ggcgaggcac gaggccagga acgtagcgca tgacatagaa cggcgttccg acgatgcctt
    16261 gatccacgca caggcggacc atgtcggcga ccggataatg cggccgcagc gcggcctgca
    16321 aggcgaactc ccgccgcatc cgctgcagtc cgccctgccc cggcaacggc cggcgcagca
    16381 ccagatcgtg gctgtcgtaa cgcaggcgat aggtcaggtg cgacatgccg ccgtcgcagc
    16441 ggcggatgtc gggccggccg ccgacatcga cgccttgcga acgcagccag tccgtaacgg
    16501 ccacggccgc cgccgacgat tccgacaaca agggatcgtc ggaccgctgc accggcatgt
    16561 cggtgcatgt tcgcggttcc gccatcgttc ggcgacggat cgaaattccg gcggtgctga
    16621 tctgccgtcg aatcccatgg tccgaatcgg caaacgggtg ccgcgcgcgc gcctgcgaat
    16681 cgatcgatgc cacctgagca aaacgctgac gtgcgttcga tagtccaccg gcatcggacg
    16741 acgccgcaat cctcgacgat gcgtcatacg cggatgctcc gtccgtctcg ccatcgtcct
    16801 ggtcgttcgc catggcgcgc ccctgtgcga cctcctccgc cgtcgagtgc tccgcgcaga
    16861 attcgccgcc gagcacggtc ctttcgatcc aggcgccgct gcaacatcgg ccaccgtcgc
    16921 gcgaaccgat agcacgcggc cgagcccatt actggtactc gcggccgctt tcctcgcagc
    16981 aagcaggttc ccggcggtac gcgatcgtcc agatcggccg gcggtctcag ttgcaatgcg
    17041 tgatcggctc tacaagtcgg gccgctatcg agcggatgcc gtccggttcc catgccgccg
    17101 cgctgcaacc tgcaagctgc gagatcgctc cggcaaccgc acggcgctct atgcaaaagt
    17161 ccgccgcccg ctgctcgcaa cgcagtttcc acaggcgcaa gacgcgcggc accgcgaccg
    17221 tctgacgtgc cgcttccgcc tggaacccgc cactccgccg acctccaccc caggcacagc
    17281 cggcaaaacc gccaactgtc ttgaccctgt cacggcactg gcatgcaatc cacgcaacgg
    17341 ctcacgcgcc gggaggcgag ccatgacttc gttccgtaac cgggtcgcac accaggcacg
    17401 atccgcttcg cgcgacatgc ggcgatacct ggcgtgtctc gccctgttgc cggcggcatg
    17461 gtccatggct gccaacgccc aggacccgca atggcgaacc gtcagcgatg aagacggcat
    17521 ccgcctggaa acccggcgca tcgccggcga acgcttcgac gaactgcgca tcactacgtc
    17581 gctgaaagcc tcgccggagg cggtcgcgga ttacctgttc ggaaagtatc tcgacgaaaa
    17641 gaacaagaac atccgccgca ccttcatcga gcgcggccgc gagctgaccg tctggtccga
    17701 cgtcctcagc acgccggtca ccagcgagcg ctgttactcg atgcgctttg agcggcatgc
    17761 gctcgccaac caggcgatac gggtgaagtt cacctccctc gactatgtcg gcaggaaacc
    17821 gaccgccgac tgcatcgcgc tgcgctcgcg cggcgagtgg gtcctgacgc cggcgggcac
    17881 cgggacgcga ttgacgtatg cctcgctgac ggacatcggc ggcaacgtac cggcgatgct
    17941 cgtgcgtcgc tcgctgtcgt cggcggcgat ttccagcgtg cgcaaggtcg cggcgggctc
    18001 gtccgggctg gcgctgcccc ggggcctagg cgactgagag tcgagcctcc gcggccgccg
    18061 cgatctttcg atcttcgcca gcccccgctg cccgacttcg atcttcaggg catccaccac
    18121 gaagtcgatg aacgcacgca ccttcgccgc gcggtgatga cgcgagggac agatcgcata
    18181 cggcgcaagg cgctcgtccg accgctcagg gcacagttcg atcaagcggc cgctgcgcag
    18241 caagtgctcg cagccgatct ccagtacctc atcgatactg gcaccggcct cgcaagcccc
    18301 gggcatggcg cccctatccg aagtgagcag gcgtcctttg acccgcagcg gcagcacttt
    18361 gttcttgcgc cgcatctccc actcatgggc ccgtccgagc actgcgtcgt agaagtcgat
    18421 gcaatcggcc tgctcgatgt ccttgagatg cttcggtcgg ccgcgggtct tgaggtaagc
    18481 gggcgaagcg accgtgatga cccgggttgg cgtcaagatg agatcgatga tcaactcggt
    18541 cttgcgcgga ctggtggcgc ggaccgcctg atcgcgccgt gcgttgttgc gccgccgcat
    18601 gccgacacgg cgcgatggag gcatcgcgcc gttcgctcat cggcaggatc ttcgatgcgc
    18661 ccgggcccag cactaaaaac atgtgacgag gttccattga aacattgttg tccgtcggtc
    18721 tttgagaggc cgcaacacca gcatcgacat cgccgatcgg actcaacggc aaatgcgcga
    18781 agtgtccgcg tcgcccattc ataagcgttt gtccgcgcat caaacgggcc gcttgaacac
    18841 gccggcaacg accgaggcga tgcctcgaaa accactgcgc tgaaaggcct tcagccattc
    18901 gcaaagtacc ggcgaacgac aagcgcgcga acggatctac gtcgacgcaa acgcggttcc
    18961 accccaacgc tgacgcgcat gcggctcgtc tgccgatgcc gaagcgacgg catcccgcgc
    19021 cattcccatg ctgcgccgcg acaaagaaac cggccgagaa aacgctttct gtcgagttcg
    19081 ctgcatggct tgtccgattt tattgacagc gctgtcagtc cgcgtgtcaa atcgccccgc
    19141 ggcactttcg gggcatgcag gatgtacctg catatccatc gcaagatcct ggggaggagt
    19201 ttcgatgaag caaacgcgtg ttgccccacg gcacacccta ttggcgtccg cactgttgtt
    19261 ggtgctcggc cagccggtgt acgcacagac gaccacaccg acgccgggca ccgctgccga
    19321 cgcgcagcca aaacccgacg ccgaacgaga cgcgaggacg ctcgacacgg tcgtcgtcac
    19381 cggcatcaag ggaagcctga cctcgtcgat gaacctcaag cgcgacgcgc agggcgtcgt
    19441 cgacggcatc gccgccgagg acatcggcaa gttccccgac accaacctgg ccgaggcgct
    19501 gcagcgcatc agcggcgtgt cgatcgaccg cagcaacggc gaaggctcgc gcgtgaccgt
    19561 gcgcggcgtc ggtcccgatt tcaacctcgt gctgctcaac ggccggcaga tgccgaccgc
    19621 caccggcggc cgcgcttttg aattcagcga cctggcggcc gagtcgatct cggcggtcga
    19681 ggtctacaag accagccgcg ccgccacgcc caccggcggc atcggcgcga cgatcaacat
    19741 caagaccgcg cgtccgctgg acaatcccgg cctgcacgcc aatgccggca tcaagggcat
    19801 ctgggacggt tccgacgacg atctgccggg cgactacaaa ggcagctcgg tcactccgga
    19861 cgcgtccggc atcttcagca acacctcggc cgacggccgc ttcggcatcg cgctgagcgc
    19921 gaattacctg aagcgcgaat cgggctcggc ttcggcgttc gtggcctcgg gcaacggctg
    19981 gcgtccgttc atcgataccc cgcagcccaa cggcgaaggc gcgggttcgg cgctgccgct
    20041 gcccggccag cccggttcgg ggaacatcac caaccgcccc ggtccgaacg acgtctattc
    20101 gatgccgcaa agcctgggtt acagcatcaa ctcggtcaaa cgcgaacgcc tcaacagcca
    20161 gctcaccttc cagtgggcgc cgaccgacaa cctcaccgcg acgctcgact acacctactc
    20221 gcagaacaag atcgagcagc tgcgcaacga catgtcggtg tggctcaact tcacccccgg
    20281 cacgagttcg tggaccaagg gttcgggctc ttcgccgacg tattacgacg agcgctacaa
    20341 cggcaattcc gacttcgcca acggcgcgag caagaccgcg gtcaagcgcg agaacaagtc
    20401 ggtcggcctc aatgtcgact ggcgcgtggc cgacaatttc aagttgaatc ttgactacca
    20461 ccgctccacc gccgattcct cgcccgacag tccgtacggt tcgagcaata cgctgggcgc
    20521 cgccggcttc ttccgcgccg gcaacaccat cgacttcagc cgcgatttcc cggtgctgac
    20581 cctgcatctg ccggccggca tgaccgcgat cgatccggcg cagatgctgg tggccggctc
    20641 ggtgttccgc aacgatatgc atcgcgcgga aatcgagcag ttccaggcca acggcgagtt
    20701 cgagttccag aactactcca agctcaattt cggcgtcgcc tcgaccgact acgaaaaccg
    20761 ctcggccttc accaacgtcc agctcgatac ctggggcggc gccaccagcg tcaatgacta
    20821 tcccgattcg gtctggcagt tgcagcacat gggcgacttc ttcaacggcg ccagcggcag
    20881 ccgcgatccg aagttcaccg attcgttctt cctgttcgat ttcgaccagg tgcgccaact
    20941 ggccgaggac gcgtgggtcg ccgccggcaa gggcagccgc gaggactacc gcgcttcgtt
    21001 cgactacagc ggcgccgcgg ttcccggcag caccgccaac cgcaccgtgg gcgacagcca
    21061 ggtgcgcgag aagtcgagca gcttctacct gcagtggagc aataccttcg agtggaagct
    21121 gccggtcaac ctcgccgccg gcgtgcgcta cgagcgcacc aaggtcaagg cctcagcgct
    21181 gcagcccgcg ccgtcgggca tcgactggct gtcggagaac gagttcatca tccgctactc
    21241 cggttcgcag ttccgcaatc tcgacggcga ctacaagtac tggctgccga gcctggacgt
    21301 gtcggtggac ttgaccgaca gcatgaagct gcgcgccagc tacggcgaat cgatcggccg
    21361 gccgaactgg ggcagcctga atccggcgct gagcgtcggc ggtcaggcgc gctacgacgg
    21421 cggcggcggc ggcgcgggca atcccgggct caagccgctg gaatcacgca acttcgacct
    21481 gtcctacgag tggtactacg gcgagtcgag ctatttctcg gtcggctatt tccgcaagaa
    21541 gatcgacaac ttcatcgccg atcaggtcag ccgccagact ccttatccgg atctgcacac
    21601 gcccgcgggc ggcgcgtact ggaaccaggc catcgcccag ggctgcgccg ccaccgaccg
    21661 gccgtgcatc cgcaactaca tcctcaacac ctacaacggc cagcccggcg tggtcaaaac
    21721 cggcgtcgac gctaacggca tcgccaccgg caccatcacc ggccagcccg gcgatccggt
    21781 gctggcattc aacatcaccg caccggtcaa caaccgcgcc gatacgctcg acggttggga
    21841 attcaacctc cagcacgtgt tcggcgactc gggtttcggc ctggcggcca actacaccat
    21901 cgtcaattcc ggcctgacct acgacgacgg gcgcctgggc acccagttcg cgatgaccgg
    21961 gctgagcgat tcggcgaacc tcgtcgcgtt ctacgaaaaa ggcccgtggc aggcgcgcgc
    22021 cgcctacaac tggcgcgaca agttcctgac ctcgctgggc gacggcaagg gcgccaatcc
    22081 gatctacgtg gaagcctacg gacagttgga catgaacgtc agctacgcgg tcaccgacaa
    22141 tctggtgctg tcgctggaag gcatcaacat caccgacgag accatgcgga cccacgggcg
    22201 caacacgcgt cagttgtact cctacgacca gtccgggccg cgctacatgt tcggggtgcg
    22261 ctacaagttc tgatcgctgc gaccgcgacg cctcgccgtt ggcgcaccgg gtcctgcttc
    22321 ggcaggcccg tgcggcgcca gcggccggcg cggcgaacac cgtcctcggc catcgcccgt
    22381 cgcctgccgc catgacgaca cgacaggcct tcccctcggc gcgtcgcggg tacatcctcg
    22441 tcggtgcagc ctcctcggac gccgccacgc ggacacgcgc ggcggctggt tccgcggaca
    22501 ttcgggccag ggcgccacgc cacccatggc ccgcaccgag cacgcaccga tcttggaaac
    22561 cgcgatgccc caggccgtac tgctcaacaa tatcgaccat cacgacctgc gcgtaatcac
    22621 cgcccgcggc gctcgctacg gcgacgacac gatgctggcg ccgacgttct ttcgcgagtt
    22681 ccgcgacttg caggcgtact acccgatcgt cttccagaag accgcgcaag gcggtttcca
    22741 gccgatggcg ctgctcggcc tgcgggcgga cgaaaacctg tttctcgaca agcgattcct
    22801 cgatgggcgc aaccaaatcc agcgctggga cgcgcattac ctgccgatcg cggtcgagcg
    22861 cctgc
//
