LOCUS       NZ_CP076103            22218 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Lysobacter capsici strain NF87_2 chromosome, complete genome.
ACCESSION   NZ_CP076103
VERSION     NZ_CP076103.1
KEYWORDS    RefSeq.
SOURCE      Lysobacter capsici
  ORGANISM  Lysobacter capsici
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J., Liu,Y., Liang,X., Zhou,Y. and Liu,J.
  TITLE     Characterization of Lysobacter capsici strain NF87-2 and its
            biocontrol activities against phytopathogens. European Journal of
            Plant Pathology
  JOURNAL   Eur J Plant Pathol 155 (3), 859-869 (2019)
REFERENCE   2  (bases 1 to 6315468)
  AUTHORS   Liu,Y., Qiao,J. and Liu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2021) Institute of Plant Protection, Jiangsu
            Academy of Agricultural Sciences, No. 50 Zhongling Street, Nanjing
            210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: nextDenovo v. 2.0-beta.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018732085.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 13:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,303
            CDSs (total)                      :: 5,240
            Genes (coding)                    :: 5,174
            CDSs (with protein)               :: 5,174
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 16 of 66
            Pseudo Genes (incomplete)         :: 52 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:02:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4428800
            Orig. end                         :: 4451018
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076103.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22218
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="9"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22218
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22218
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12218](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12218
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    2..11
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            complement(93..749)
                     /locus_tag="KME82_RS18390"
                     /old_locus_tag="KME82_18390"
     CDS             complement(93..749)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005419171.1"
                     /locus_tag="KME82_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18390"
                     /product="response regulator transcription factor"
                     /protein_id="WP_215495338.1"
                     /transl_table=11
                     /translation="MSDTLRILIADDHPMFRAALRFALGEIAPGAAMVEVSSQSALEAA
                     IASGEEFDLAMLDLMMPGAMGFSSLVYARGERPELPVVIISSNEHPRTIRRAQQFGASG
                     FVPKSAPSTVLAEAVNAVLAGNIWFPPQQVERDEGDAQLADRLAQLTPQQMRVLLRLAD
                     GLLNKQIAYELSLAENTVKIHVTAILRKLGCHSRTQAAVLVKGLSLEDDAAGLHD"
     gene            complement(1084..2070)
                     /locus_tag="KME82_RS18395"
                     /old_locus_tag="KME82_18395"
     CDS             complement(1084..2070)
                     /EC_number="1.1.1.37"
                     /GO_function="GO:0016615 - malate dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006108 - malate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012439107.1"
                     /locus_tag="KME82_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18395"
                     /product="malate dehydrogenase"
                     /protein_id="WP_215495339.1"
                     /transl_table=11
                     /translation="MKTPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLELPL
                     EKAQAALKGVIMELEDCAFPLLAGVVGTDDAEVAFKDADIALLVGARPRGPGMERKDLL
                     LENAKIFTAQGAALNKVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHN
                     RALSQLAAKAGVAVGDIESLVVWGNHSPTMYPDYRFATVNGQSLKDKINDAEWNANTFI
                     PQVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGVPSDGSYGIPETVM
                     YGVPVITENGEYKRVEGLEVDAFSRAAMDKTLAELEEERAGVAHLLG"
     misc_feature    2127..2143
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            complement(2158..2544)
                     /locus_tag="KME82_RS18400"
                     /old_locus_tag="KME82_18400"
     CDS             complement(2158..2544)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003806614.1"
                     /locus_tag="KME82_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18400"
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_215495340.1"
                     /transl_table=11
                     /translation="MRVTTVLWIALAAAVGIGGVKLIKANGLDLFASRPAELKPDDPRH
                     TTGDKRIVMLAADWCGYCEKLRKDFELANVRYSLIDIDTEAGQRAMEAVGARGVPVTII
                     GQDIVYGYNLDQIKDRMEPLGYRL"
     gene            complement(2606..3811)
                     /locus_tag="KME82_RS18405"
                     /old_locus_tag="KME82_18405"
     CDS             complement(2606..3811)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-386). E-value:
                     1.3e-63. Score: 207.3. Matches aSDomain:
                     nrpspksdomains_KME82_RS18405_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007509893.1"
                     /locus_tag="KME82_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18405"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_215495341.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-61, bitscore:
                     207.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQLARRIGRAKPSAIMQVAEKAKRLKAEGRDIISFSIGVPNFLP
                     GDHVYAAVREALAKDSGQYGSNRGADALLDAFIEHMGKIGLSGYGRVNVATGIGAKHVI
                     YNIAEALLDEGDTIVFPTPYWTSYLDIAEIVNAKIDLLPCPASQDYKLTPEQLDAALAK
                     KPRVFLFNNPSNPTGMVYGKEEIDALADVVAKYPDTWVITDDIYNRMVFDGLGYHNFVH
                     SRPELRDRVIFIDSLSKTYGMPGWRVGFMAGPEVIAQAVTTMNSNHITNIPEIVTAAAV
                     AALSGPQDVPTARCAEFQAKRDQVMDVMNSIPGVICPRPQGAFYVFPDISVAFGKTHGP
                     SGLKIENDMDLCNALLETKGVACVPGSAFGEPRALRISYTCPTPQLAPGLQRFQEFFAE
                     LA"
     aSDomain        complement(2654..3718)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KME82_RS18405_Aminotran_1_2.1"
                     /evalue="1.30E-63"
                     /label="KME82_RS18405_Aminotran_1_2.1"
                     /locus_tag="KME82_RS18405"
                     /protein_end="386"
                     /protein_start="31"
                     /score="207.3"
                     /tool="antismash"
                     /translation="DIISFSIGVPNFLPGDHVYAAVREALAKDSGQYGSNRGADALLDA
                     FIEHMGKIGLSGYGRVNVATGIGAKHVIYNIAEALLDEGDTIVFPTPYWTSYLDIAEIV
                     NAKIDLLPCPASQDYKLTPEQLDAALAKKPRVFLFNNPSNPTGMVYGKEEIDALADVVA
                     KYPDTWVITDDIYNRMVFDGLGYHNFVHSRPELRDRVIFIDSLSKTYGMPGWRVGFMAG
                     PEVIAQAVTTMNSNHITNIPEIVTAAAVAALSGPQDVPTARCAEFQAKRDQVMDVMNSI
                     PGVICPRPQGAFYVFPDISVAFGKTHGPSGLKIENDMDLCNALLETKGVACVPGSAFGE
                     PRALRISYTCPTPQL"
     misc_feature    4093..4106
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    4376..4390
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
     gene            complement(4437..4943)
                     /locus_tag="KME82_RS18410"
                     /old_locus_tag="KME82_18410"
     CDS             complement(4437..4943)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009607495.1"
                     /locus_tag="KME82_RS18410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18410"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_046657632.1"
                     /transl_table=11
                     /translation="MSLIATFDTSRGPIRVELAADKAPLTVANFVNLAQRGFYDGLAFH
                     RVIPNFMVQGGCPQGTGTGGPGYRFEDETRNGLSHQRGVLSMANAGPGTNGSQFFITHV
                     VCDWLDGKHTVFGKVLDGQEIVDTIKQGDAINSIKIEGDTAAVLAAKADRVADWNKILD
                     ENKRP"
     gene            5467..7296
                     /gene="typA"
                     /locus_tag="KME82_RS18415"
                     /old_locus_tag="KME82_18415"
     CDS             5467..7296
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="typA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014161352.1"
                     /locus_tag="KME82_RS18415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18415"
                     /product="translational GTPase TypA"
                     /protein_id="WP_056110783.1"
                     /transl_table=11
                     /translation="MSIERLRNIAIVAHVDHGKTTLVDCLLKQSGTLSERTVLAERAMD
                     SNDQEKERGITILAKNTAITWQGNRINIVDTPGHADFGGEVERVLSMVDSVLILVDAMD
                     GPMPQTRFVTQKAFAMGFKPIVVVNKIDRPGARPDWVIDQVFDLFDKLGATNEQLDFPI
                     VYASALHGYASLDDAARSGDMTPLYEAIMKHVPPPEVDLDGPFQMRISQLDYSNFVGLI
                     GIGRIQRGKVRRNMPVSVVDREGKKRQGKVLQVLGFMGLERLETEEAEAGDIVAISGVA
                     DLSISDTVCALDTPEALPALTVDEPTISMTFQVNNSPFAGQKEHSGGKFLTSRQLRERL
                     QRETLHNVALKVEEGSDPDKFLVSGRGELHLSVLIENMRREGFELAVSRPEVIIKEIDG
                     KLMEPVEQLVVDIEEQHQGGVMEKLGTRKAQLKDMVSDGKGRVRLDYMIPARGLIGFQN
                     EFRTLTQGSGLLFHVFDHYGPKEQGAIAKRINGVMIANAPGTTPAYSLGPLQERGKLFA
                     AEGDNVYEGQLIGIHSKDNDLTVNAIKTKPLTNMRASGKDDAIQLSPAIKYTLEQALDF
                     IEDDELVEVTPKEIRLRKKFLTESDRKRASRAA"
     misc_feature    5474..5489
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.56"
                     /tool="antismash"
     gene            7376..7903
                     /locus_tag="KME82_RS18420"
                     /old_locus_tag="KME82_18420"
     CDS             7376..7903
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KME82_RS18420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KME82_18420"
                     /product="hypothetical protein"
                     /protein_id="WP_215495342.1"
                     /transl_table=11
                     /translation="MELRDLIWWFAGLAPGLLLGWWLGARKRPATTQVEATATPSPPQP
                     QRPPAPAQAAPAATPVAPATPAPEAAPAAHAAEPPAPAVPVWSPDVQALFDKGETIEAI
                     KKIRNTLGGPVARKVAREHLSEGEFRLPADIRKLADANKKLEAIRLLCDQTHMDMPLAQ
                     RLVEHYVAHPTR"
     misc_feature    7382..7384
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7900..8373
                     /locus_tag="KME82_RS18425"
                     /old_locus_tag="KME82_18425"
     CDS             7900..8373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659569.1"
                     /locus_tag="KME82_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18425"
                     /product="DUF2127 domain-containing protein"
                     /protein_id="WP_215495343.1"
                     /transl_table=11
                     /translation="MTETETHYDANPKAHPGLHVIAAVEAVKGALALSAASGLELLGPA
                     PLQRWIGELIKRFHLDPEHGSLAWLAHTISPHSVHLAAAVVLAYGLLHLVEAWGLWKAK
                     AWASWLGCLGAALYLPFDIYAMFRHPGWLATAVLIINLIVVWVLARDILKRRQ"
     misc_feature    8650..8667
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.77"
                     /tool="antismash"
     misc_feature    complement(9007..9022)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.32"
                     /tool="antismash"
     gene            9036..9965
                     /gene="pqqB"
                     /locus_tag="KME82_RS18435"
                     /old_locus_tag="KME82_18435"
     CDS             9036..9965
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011038060.1"
                     /locus_tag="KME82_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18435"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_215495345.1"
                     /transl_table=11
                     /translation="MRILVLGAAAGGGYPQWNCNTPGSQRAWRQEPGHQRRTQASIAVS
                     ADNERWLLINASPDFRQQILAQPALWPKRDLRHSPIEAVLLTSGEIDHIAGLLSMRERQ
                     RFDLWASARVLDVLSQNPIFDSLHPDYVARKALSLDTPIEVAGHDAPLGLRVTAFSVPG
                     KVPLFMESRANGNLQGGDEETVGLEISDGRERFLYIPGCAAMTDDLRRRLHGASLVLFD
                     GTLWRDDEMVRAGVGSKTGARMGHMNIAGDGGEDGGTLAAFAPLEVRRKLFIHLNTTNP
                     LLDDHSPERAQARAHGWEVAEDGMELQL"
     gene            10001..10762
                     /gene="pqqC"
                     /locus_tag="KME82_RS18440"
                     /old_locus_tag="KME82_18440"
     CDS             10001..10762
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017155549.1"
                     /locus_tag="KME82_RS18440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18440"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_252255835.1"
                     /sec_met_domain="TIGR02111 (E-value: 6.6e-119, bitscore:
                     393.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDDALLTPAQLEARLRAIGAERYHDKHPFHHLLHSGRLNRGQVQ
                     AWALNRFEYQRCIPLKDAALLARIEDPQLRRVWRQRIVDHDGERDGDGGIARWLHLTDA
                     LGLDRATVESGRALLPATRFAVQAYIHFVRERSLLEAIASSLTELFAPTIIGQRVSGML
                     ANYDFVSRQSLAYFDSRLHQAPQDANFALDYVKRHALTRAQQDAVCAALRFKCEVLWSM
                     LDALHLAYVEPRLIPPGAFRPDEAGPDEAGA"
     gene            10759..11055
                     /gene="pqqD"
                     /locus_tag="KME82_RS18445"
                     /old_locus_tag="KME82_18445"
     CDS             10759..11055
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003472335.1"
                     /locus_tag="KME82_RS18445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18445"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_215495346.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.1e-31, bitscore:
                     105.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.2e-15, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.7e-09,
                     bitscore: 33.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAIEATAVPRFPAGVRLQHDRARDQWVLLAPERVVELDEIAHA
                     VLARVDAASDVEAIVQALAAEYGAEPAQVHDDVIELFATLLEKRMLALSTPMP"
     aSDomain        10768..11034
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KME82_RS18445_PqqD_RRE.1"
                     /evalue="1.70E-33"
                     /identifier="RREFam006.1"
                     /label="KME82_RS18445"
                     /locus_tag="KME82_RS18445"
                     /protein_end="92"
                     /protein_start="3"
                     /score="105.2"
                     /tool="antismash"
                     /translation="AIEATAVPRFPAGVRLQHDRARDQWVLLAPERVVELDEIAHAVLA
                     RVDAASDVEAIVQALAAEYGAEPAQVHDDVIELFATLLEKRMLA"
     aSDomain        10867..11034
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KME82_RS18445_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.60E-11"
                     /identifier="RREFam002.1"
                     /label="KME82_RS18445"
                     /locus_tag="KME82_RS18445"
                     /protein_end="92"
                     /protein_start="36"
                     /score="33.9"
                     /tool="antismash"
                     /translation="VELDEIAHAVLARVDAASDVEAIVQALAAEYGAEPAQVHDDVIEL
                     FATLLEKRMLA"
     gene            11052..12218
                     /gene="pqqE"
                     /locus_tag="KME82_RS18450"
                     /old_locus_tag="KME82_18450"
     CDS             11052..12218
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344292.1"
                     /locus_tag="KME82_RS18450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18450"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_215495347.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-21, bitscore: 75.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.9e-05, bitscore: 23.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.3e-10, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.8e-10, bitscore: 37.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVEAASVVATTGLAPSKAPAPAPPLAVLLELTHRCPLSCPYCSN
                     PLQLVGMREELATADWLRVLDQAAELGVLQVHYSGGEPTLRKDLPELLRHARALGLYCN
                     LITSGVGVTRERLQELQQAGLDHLQLSIQDSQAAGADRIAGYAGSHERKLALARWCGEL
                     DLPLTLNAVVHRHNAERVAQMIDLALDLGAGRLEVAHTQYYGWGLSNRAALMPTRAQLD
                     AVTAVVEDARQRLRGRLTIDYVTPDYYARRPKACMGGWAQRFVNITPDGKVLPCHAAET
                     LTELRFDSVRDRSLGDIWRDSDAFVRYRGTDWMPEPCRGCERREIDWGGCRCQALALSG
                     RADTLDPVCEKSPDHARVRALAQAESAAPAPEFIYRRLRATGAKAATD"
     gene            complement(12249..12614)
                     /locus_tag="KME82_RS18455"
                     /old_locus_tag="KME82_18455"
     CDS             complement(12249..12614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KME82_RS18455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KME82_18455"
                     /product="hypothetical protein"
                     /protein_id="WP_215495348.1"
                     /transl_table=11
                     /translation="MNSTTPTQAAPRDPRIDAAVARLLGNRDDEIEGTFCHGLFERGVF
                     DAALFESLVGDMRLVASDASAYPAHRATIVWIALGVCRCVFSHFDADDGYRIVNLDDAL
                     YSKWSGDYFERLRELLD"
     gene            12838..14478
                     /locus_tag="KME82_RS18460"
                     /old_locus_tag="KME82_18460"
     CDS             12838..14478
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019237915.1"
                     /locus_tag="KME82_RS18460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18460"
                     /product="amidase"
                     /protein_id="WP_215495349.1"
                     /transl_table=11
                     /translation="MPAFHCTARLGLAALTLALAGCAGPQAVRAPRPVVASDEAAKGFL
                     PTDPLRLAEADTAALSARMSNGELSSVRLTQGYLDRIAALDDAGPQLNAVIELNPDALA
                     EARKLDEERKAGQLRGPLHGIPVLIKDNIDATPMVNSAGSLALAEHRPKTDAPIVAALR
                     RAGAVILGKTNLSEWANFRSTHSISGWSGRGGLTRNPYVLDRTACGSSSGTGAAIAASL
                     AAVGVGTETDGSILCPAAMNGLVGFKPTVGLVSRQGIIPISHSQDTAGSMARSVADAAQ
                     LLSVLVSAEAGGDSAAQASADKRLADYVGGLDGDALHGARLGLLRESGVGQLPAIDAAL
                     ERALKTLRDAGATVVEVKIATAGQWDRAEGEVLRYEFKDGLERYLRESGAPVKTLGELI
                     AFNRTHAAREQPYFGQELFEQADKKGSLKDPAYRKFAAQARQLAGPQGIDATLKRHKLD
                     ALIAPATTPAFMVDPVNGDPFGGASWGAAAVAGYPSLTVPMGEASGLPIGLVFMGKRWS
                     DAQLLSLGYAFEQLTLARTPPGYRVTLSP"
     gene            complement(14760..15203)
                     /locus_tag="KME82_RS18465"
                     /old_locus_tag="KME82_18465"
     CDS             complement(14760..15203)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011035594.1"
                     /locus_tag="KME82_RS18465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18465"
                     /product="hypothetical protein"
                     /protein_id="WP_215495350.1"
                     /transl_table=11
                     /translation="MSGERNRALLAAGTLSALAALLHLGCIVFGAPWYRAFGAGEWMAQ
                     ASIAGHWHPVVATLAIASVLTVWSLYAFSAAGALHRLPLLRTVLCLVTAVYLLRGVAAV
                     PMMSVFPGRSLNFWLWSSGICLGIGVVHLIGLLQVWKRLGRLS"
     gene            complement(15236..16630)
                     /locus_tag="KME82_RS18470"
                     /old_locus_tag="KME82_18470"
     CDS             complement(15236..16630)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036136.1"
                     /locus_tag="KME82_RS18470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18470"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_036111723.1"
                     /transl_table=11
                     /translation="MSASDRNSNLRAVNLPADWSPTSWRERTALQLPSYPDAADLESAL
                     QELRQLPPLVTSWEILSLKQQLAEAQEGKRFLLQGGDCAESFDQCSSDVISNRLKVLLQ
                     MSLVLVHGMRKPVVRVGRFAGQYAKPRSADTETIDGVTLPSYRGDMVNAPAFNEAARRP
                     DPRRMIKGHARSAMTMNFVRALIDGGFADLHHPEYWNLSWVGHSPLADEYRRMVNAIGD
                     AVRFMETLSGSEVHNLNRVDFYTSHEALLLPYEESMTRQVPRHWGHFNLSTHYPWIGMR
                     TAAVDGAHAEYFRGIRNPIALKVGPSVTPDQLLRTIDLLNPEDEPGRLTFIHRMGATAV
                     AEKLPPLLDAMRRDGRRVLWVCDPMHGNTESTSNGYKTRRFRNIRAEIETSFELHAAAG
                     TRLGGVHLELTGEDVTECLGGARELTESDLERAYRSTVDPRLNYEQALEVAMLIVRKQA
                     QIAAPA"
     misc_feature    16595..16608
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    complement(16623..16634)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(16728..17228)
                     /locus_tag="KME82_RS18475"
                     /old_locus_tag="KME82_18475"
     CDS             complement(16728..17228)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005993394.1"
                     /locus_tag="KME82_RS18475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18475"
                     /product="disulfide bond formation protein B"
                     /protein_id="WP_215495351.1"
                     /transl_table=11
                     /translation="MNPFKASFRIQFLLGFLACAGLLAYAVYLQVYQHLEPCPLCIFQR
                     VAFAALGVVFLLGALHGPKKPGGRRSYGVLALLASLGGIAVAGNHVRLQHLPPDQVPAC
                     GPGLNYMLDAMPITGVIKKVMTGSGECANVDWTFLGLAMPAWSLICFIVLALWAAYAAF
                     RGR"
     misc_feature    complement(17523..17539)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            complement(17567..17941)
                     /gene="rplQ"
                     /locus_tag="KME82_RS18480"
                     /old_locus_tag="KME82_18480"
     CDS             complement(17567..17941)
                     /GO_component="GO:0005762 - mitochondrial large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004145464.1"
                     /locus_tag="KME82_RS18480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18480"
                     /product="50S ribosomal protein L17"
                     /protein_id="WP_031373811.1"
                     /transl_table=11
                     /translation="MRHQKSGRKFSRTSAHRDAMFTNMAASLIKHGLIRTTLPKAKELR
                     RVAEPLITLAKKDGVANRRLAFSRLRDKEAVGTLFVELGPRYASRPGGYLRILKCGFRA
                     GDNAPMAYVELVDRPQAAAE"
     gene            complement(18236..19234)
                     /gene="rpoA"
                     /locus_tag="KME82_RS18485"
                     /old_locus_tag="KME82_18485"
     CDS             complement(18236..19234)
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020852431.1"
                     /locus_tag="KME82_RS18485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18485"
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="WP_036111743.1"
                     /transl_table=11
                     /translation="MTVTANQVLRPRGPQIERLTGNRAKVVIEPLERGYGHTLGNALRR
                     VLLSSIPGFAITEVEIDGVLHEYTTVEGLEEDVLEVLLNLKDVAIRMHTGDASTLSLAK
                     QGPGIVTAGDIKTDHNVEILNTDHVICHLTKDTAINMRLKIERGFGYQPAASRRRPDEE
                     TRAIGRLMLDASFSPVRRVAYAVEAARVEQRTDLDKLVLDIETNGTIDAEEAVRTAADI
                     LTDQLSVFGDFTHRDRGAAKPATSGIDPILLRPIDDLELTVRSANCLKAESIYYVGDLI
                     QKTEVELLKTPNLGKKSLTEIKEVLAQRGLSLGMKLENWPPAGIASHGMMG"
     gene            complement(19393..20022)
                     /gene="rpsD"
                     /locus_tag="KME82_RS18490"
                     /old_locus_tag="KME82_18490"
     CDS             complement(19393..20022)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004145446.1"
                     /locus_tag="KME82_RS18490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18490"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_036111747.1"
                     /transl_table=11
                     /translation="MARYIGPTCKLARREGADLGLKSSARALDSKCKLEQKPGQHGPTA
                     RKGKLSDYATQLREKQKVKRIYGLLERQFRNYYKKASTKKGNTGENLLQLLETRLDNVV
                     YRMGFAVTRPAARQLVSHRGVTVNGKSVNLPSYQVKAGDAIALSERAQKQLRVQESLTV
                     SSQMDLSPSWVEVDSKKFSGVFKAVPDRADLPADINEALIVELYSK"
     gene            complement(20037..20429)
                     /gene="rpsK"
                     /locus_tag="KME82_RS18495"
                     /old_locus_tag="KME82_18495"
     CDS             complement(20037..20429)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017939146.1"
                     /locus_tag="KME82_RS18495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18495"
                     /product="30S ribosomal protein S11"
                     /protein_id="WP_036111750.1"
                     /transl_table=11
                     /translation="MAKPAAVKTKKKIKRIVTDGIAHVHASFNNTIITITDRQGNALSW
                     ATSGGAGFRGSRKSTPFAAQVAAEKAGRAALDYGVKSLEVRIKGPGPGRESAVRSLNNV
                     GYKIINIIDVTPIPHNGCRPPKKRRV"
     gene            complement(20443..20799)
                     /gene="rpsM"
                     /locus_tag="KME82_RS18500"
                     /old_locus_tag="KME82_18500"
     CDS             complement(20443..20799)
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215453.1"
                     /locus_tag="KME82_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KME82_18500"
                     /product="30S ribosomal protein S13"
                     /protein_id="WP_036111754.1"
                     /transl_table=11
                     /translation="MARIAGVNLPAQKHVWVGLQSIFGIGRTRSKQICQTAGVTSTTKI
                     RDLSEPEVERLRAEVGKFVVEGDLRREVGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRT
                     NARTRKGPRKAIKK"
     misc_feature    complement(20961..20975)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.98"
                     /tool="antismash"
     misc_feature    21133..21148
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    21135..21149
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 tcgttttttg ccagcgccgc acatggactg tctacagcga aagcggcgat tgagaacttg
       61 ccgacaacga tcccgaccgc cgcgcagcaa acctagtcgt gcaagcccgc cgcgtcgtct
      121 tccagcgaca gccccttcac caacaccgcc gcctgcgtgc gcgaatggca gccgagtttg
      181 cgcaggatcg cggtgacatg gatcttgacc gtgttctcgg ccagcgacag ctcgtaggcg
      241 atctgcttgt tgagcaggcc gtcggccagt cgcaacagca cccgcatctg ctgcggggtg
      301 agctgggcga ggcgatcggc gagttgcgcg tcgccttcgt cgcgttcgac ctgctgcggc
      361 ggaaaccaga tgttgccggc gagcaccgcg ttgaccgctt cggccagcac cgtcgacggc
      421 gccgacttgg gcacgaaacc cgacgcgccg aactgctgcg cgcggcggat cgtgcgcggg
      481 tgttcgttcg aggaaatgat caccaccggc agttcggggc gttcgccgcg cgcgtacacc
      541 agcgaggaga aacccatcgc gccgggcatc atcaggtcga gcatggccag gtcgaactcc
      601 tcgccgctgg cgatcgccgc ttccagcgcg ctctggctgg acacctcgac catcgccgcg
      661 ccgggcgcga tctcgcccag cgcgaagcgc aacgccgccc ggaacatcgg gtggtcgtcg
      721 gcgatcagga tgcgcagggt gtcgctcatc ggatggggtc cctcggacgt ggagcgggac
      781 cgatcctaca cggtcgggga cggtgcggga cttcggcttg ctttgcctgg atcggcttgc
      841 aggcccggtc ctgtttgcgg cgtgcgacgg ggggctatat gcgggagagc cgggggaagg
      901 cacacgaggc cgctgatcgc atcgctcgcc atgattcgcg cgccctcatc cggcccttcg
      961 ggccaccttc tcccgtgaac gggagaagga ttcgtccccc gcacgcgtaa gcgaccaagc
     1021 ccgactcaaa aaaatggggc ggccgaagcc gccccattca tgcctcgcga tcgcgtccgc
     1081 cgatcaaccc agcagatgcg ccacgccggc gcgctcttcc tcgagctcgg ccagggtctt
     1141 gtccatcgcg gcgcggctga acgcgtccac ttccaggcct tccacgcgct tgtactcgcc
     1201 gttttcggtg atcaccggca cgccgtacat caccgtctcc gggatgccgt agctgccgtc
     1261 ggacggcacg cccatggtca cccacttgcc gttgctgccg agcacccaat cgcgcacgtg
     1321 gtcgatcgcg gcattggccg ccgacgccgc cgacgacagg ccgcgcgctt cgatgatcgc
     1381 cgcgccgcgc ttgccgacct gcgggatgaa ggtgttcgcg ttccactcgg cgtcgttgat
     1441 cttgtccttc agcgactgcc cgttgacggt ggcgaagcgg tagtccgggt acatggtcgg
     1501 gctgtggttg ccccacacca ccaggctttc gatgtcgccc acggcgacgc cggccttcgc
     1561 ggcgagctgg ctcagcgcgc ggttgtggtc caggcgcagc atcgcggtga agttcttggc
     1621 cggcaggtcc ggcgccgact tcatcgcgat gtaggcgttg gtgttggccg gattgccgac
     1681 caccagcacc ttgacgttgc gcgaagccac cttgttcaac gccgcgccct gggcggtgaa
     1741 gatcttcgcg ttttccagca gcaggtcctt gcgctccatg cccgggccgc gcggacgcgc
     1801 gccgaccagc agggcgatgt cggcgtcctt gaacgcgact tcggcgtcgt cggtgccgac
     1861 cacgccggcc agcagcggga acgcgcagtc ttccaactcc atgatcacgc ccttgagcgc
     1921 ggcctgggcc ttctccagcg gcagttcgag caactgcagg atgacgggct gatccttgcc
     1981 gagcatttcg ccggaagcga tgcggaacag cagcgagtag ccgatctggc cggcagcacc
     2041 ggtgacggca acgcggacgg gggtcttcat cggggtcttt ccttcacgag tgaacggtat
     2101 ggcgggcacg cggcccgcgg ggttgattgc aaaccgcgcg cagcctgcgc cgcgcgctta
     2161 caggcggtag ccgagcggct ccatccggtc cttgatctgg tccaggttgt aaccgtagac
     2221 gatgtcctgg ccgatgatgg tgaccggcac gccgcgcgcg ccgacggcct ccatcgcgcg
     2281 ctggccggct tcggtgtcga tgtcgatcag gctgtagcgc acgttggcca gttcgaaatc
     2341 cttgcgcagt ttttcgcagt agccgcacca gtccgcggcc agcatcacga tgcgcttgtc
     2401 gccggtcgtg tggcgcggat cgtccggctt gagttcggcc ggacgcgagg cgaacaggtc
     2461 caagccgttc gccttgatca gcttgacccc gccgatgccg acggcggcgg ccagggcgat
     2521 ccagagcacg gtggtgacgc gcatgtcgaa gtccttgtct ctacgatcgc cgtgacgggc
     2581 cggttgccac gattccgcgc cgggctcagg cgagctcggc gaagaattcc tggaaccgct
     2641 gcaggcccgg cgccagctgc ggcgtcggac aggtgtagct gatgcgcagc gcgcgtggtt
     2701 cgccgaacgc cgagcccggc acgcaggcca cgcccttggt ttccagcaat gcgttgcaca
     2761 agtccatgtc gttttcgatc ttcagcccgc tcggtccgtg ggtcttgccg aacgcgacgc
     2821 tgatgtccgg gaacacgtag aacgcgccct gcggacgcgg gcagatcacg cccgggatcg
     2881 agttcatcac gtccatgacc tgatcgcgct tggcctggaa ctcggcgcag cgggcggtcg
     2941 gcacgtcctg cggacccgac agcgcggcca cggcggcggc ggtgacgatt tccgggatgt
     3001 tggtgatgtg gttggaattc atcgtggtca cggcctgcgc gatcacttcc ggaccggcca
     3061 tgaagcccac ccgccagccc ggcatgccgt aggtcttgga cagcgagtcg atgaagatca
     3121 cccggtcgcg cagctcggga cgcgagtgca cgaagttgtg atagcccagg ccgtcgaaca
     3181 ccatgcggtt gtagatgtcg tcggtgatga cccaggtgtc cgggtacttg gcgacgacgt
     3241 cggccagcgc atcgatctct tccttcccgt agaccatgcc ggtcgggttg gagggattgt
     3301 tgaacaggaa tacgcgcggc ttcttggcca gcgcggcgtc gagctgttcg ggcgtgagct
     3361 tgtagtcctg cgaggccggg cacggcagca ggtcgatctt ggcgttgacg atctcggcga
     3421 tgtcgagata gctggtccag tacggggtcg ggaagacgat ggtgtcgcct tcgtccaaca
     3481 gcgcctcggc gatgttgtag atcacgtgct tggcgccgat gccggtggcg acgttgaccc
     3541 ggccgtagcc gctcaggccg atcttgccca tgtgctcgat gaacgcgtcc agcagcgcgt
     3601 cggcgccgcg gttgctgccg tactggccgc tgtccttggc cagggcttcg cgcacggcgg
     3661 cgtagacgtg atcgccgggc aggaagttgg gaacgccgat cgagaagctg atgatgtcgc
     3721 ggccttcggc cttgagccgc ttggcctttt cggcaacctg catgatcgcg ctgggcttgg
     3781 cgcgaccgat gcgccgggcg agctggggca tcgtgtaaac ctcgtggggt ggtgtacgac
     3841 ggagcgtgct gggaggagac gtgctgggga ggacgctggt ggcagcggcg gcacgagggc
     3901 ggcgcgcggg tacgggcgct gtcgcctgac gcactggaac cgctggttct agccgcaaaa
     3961 tggtagcaca gggccggcgg cgggccggtt tcgaatgtgg cggttcgcgt aggtgtgatt
     4021 ggcgcttgcg taggggattg gtgagacacg gagccctaag tctccgtgcg acggccttcg
     4081 ggccagacgc tcttgactca gatcacggcg aagccgcgat ctgagcggag atcgtcgcat
     4141 cggatctgag ggcgtcgggg cagatagccc ctcccacaaa agacctcgag agcttcgaag
     4201 tcttttgtgg gagggccttc aggcccgatg ctcttggtcc agatcgctac aaagccggac
     4261 tcggactcgg actcggactc gggctcggac tcggactcgg gctcaggctc aggctcgggg
     4321 cagaaatcac cgcaccggca gacagttccc agccgaaaaa gaaaaagacg gccgctggcc
     4381 gtctttttca tcatgcccgc cgcacccgcc aaaccgggca cggcggcctg caacccttac
     4441 gggcgcttgt tctcgtcgag gatcttgttc cagtcggcca cgcgatcggc cttggcggcc
     4501 agcaccgcgg cggtgtcgcc ttcgatcttg atcgagttga tcgcgtcgcc ctgcttgatc
     4561 gtgtcgacga tctcctggcc gtcgagcacc ttgccgaaca cggtgtgctt gccgtcgagc
     4621 cagtcgcaca cgacgtgggt gatgaagaac tggctgccgt tggtgcccgg gccggcattg
     4681 gccatcgaca gcacgccgcg ctggtggctc aggccgttgc gggtttcgtc ctcgaaacgg
     4741 tagcccgggc cgccggtgcc ggtgccctgc gggcagccgc cctggaccat gaagttcggg
     4801 atcacgcggt ggaaggccag gccgtcgtag aagccgcgct gggccaggtt gacgaagttg
     4861 gcgacggtca gcggcgcctt gtcggcggcg agttcgacgc ggatcgggcc gcgcgaggtg
     4921 tcgaaggtgg cgatcaggct catgcaacgc actccaggtg tagcgatggg aagtaggaaa
     4981 acggttcgcc cgccgacatg gcgacgatgc agacaaacca caagggtaaa ggattcgccg
     5041 ccgacctccc gggggaggag cggcgtgagc cgcgacaggc cgcagcgccg aaaccccagc
     5101 cggcgcgaac atccaggatg cccggcccca ggcgtacgcc aaggacctgc gcgaggccgg
     5161 tgaagccccc tgggcacgac ttcgctgctg gcggcctcgg cgccttcaac gcagactcca
     5221 atcgcacacc gcagggagat tcagcacctt gagagcgctc ggaggctgtt tttaccgggc
     5281 cccggggatc gcgactcacg ccgctcccac cctcgtggcg ggcgcagtcc gggccaaatc
     5341 ggccgcccct gttcagccaa accgccgctc gtgaacaaat ccccgccccg gcaagcactt
     5401 gccacgtttg cccggtataa tggccggcta tctcctcagc tatagcgcct cccggcgtcc
     5461 aatcgcatgt ccatcgaacg cctgcgcaat atcgccatcg tcgcccacgt cgaccacggc
     5521 aagaccaccc tcgtcgactg cctgttgaag cagtccggca ccctgtccga acgcacggtg
     5581 ctcgccgagc gcgcgatgga cagcaacgac caggaaaagg aacgtggcat cacgatcctg
     5641 gccaagaaca ccgccatcac ctggcagggc aaccgcatca acatcgtcga caccccgggc
     5701 cacgccgact tcggcggcga ggtcgagcgc gtgctgtcga tggtcgactc ggtgctgatc
     5761 ctggtcgacg cgatggacgg cccgatgccg cagacccgct tcgtcaccca gaaggccttc
     5821 gcgatgggct tcaagccgat cgtggtggtc aacaagatcg accgcccggg cgcccgtccg
     5881 gactgggtca tcgaccaggt gttcgacctg ttcgacaagc tcggcgccac caacgagcag
     5941 ctcgacttcc cgatcgtcta cgcctcggcg ctgcacggct acgccagcct ggacgacgcc
     6001 gcgcgctcgg gcgacatgac cccgctgtac gaagcgatca tgaagcacgt cccgccgccg
     6061 gaagtcgatc tcgacggccc gttccagatg cgcatcagcc agctggacta cagcaacttc
     6121 gtcggcctga tcggcatcgg ccgcatccag cgcggcaagg tccgccgcaa catgccggtc
     6181 agcgtggtcg accgcgaagg caagaagcgc cagggcaagg tcctgcaggt gctcggcttc
     6241 atgggccttg agcgcctgga gaccgaggaa gccgaggccg gcgacatcgt cgccatctcc
     6301 ggcgtcgccg acctgtcgat ctccgacacc gtgtgcgcgc tggacacccc ggaagccctg
     6361 cccgcgctga ccgtggacga gccgaccatc agcatgacct tccaggtgaa caactcgccg
     6421 ttcgccggcc agaaggaaca cagcggcggc aagttcctca ccagccgcca gctgcgcgag
     6481 cgcctgcagc gcgaaacgct gcacaacgtg gcgctgaagg tcgaagaagg ctccgatccg
     6541 gacaagttcc tggtctcggg ccgcggcgaa ctgcacctgt cggtgctgat cgagaacatg
     6601 cgccgcgaag ggttcgagct ggccgtgtcg cgcccggaag tcatcatcaa ggaaatcgac
     6661 ggcaagctga tggagccggt cgagcaactg gtggtcgaca tcgaagagca gcaccagggc
     6721 ggcgtcatgg agaagctcgg cacccgcaag gcccagttga aggacatggt gtccgacggc
     6781 aagggtcgcg tgcgcctgga ctacatgatc ccggcccgcg gcctgatcgg tttccagaac
     6841 gagttccgca ccctgaccca gggttcgggc ctgctgttcc atgtgttcga ccactacggt
     6901 ccgaaggaac agggcgcgat cgccaagcgc atcaacggcg tgatgatcgc caatgcgccg
     6961 ggcaccaccc cggcctattc gcttgggccg ctgcaggaac gcggcaagct gtttgccgcc
     7021 gaaggcgaca acgtgtacga gggccagctg atcggcatcc actccaagga caacgacctc
     7081 accgtcaacg cgatcaagac caagccgctg accaacatgc gcgcttcggg caaggacgat
     7141 gcgatccagc tgagcccggc gatcaagtac acgctggagc aggcgctgga cttcatcgag
     7201 gacgacgagc tggtcgaagt cacgccgaag gaaatccgcc tgcgcaagaa gttcctcacc
     7261 gaaagcgatc gcaagcgcgc ctcgcgcgcg gcctgatcgc ccggctggaa gccggcaatt
     7321 gcagtaagag ccgcgcgttt ggggaaccag cgcgcgttgc aaggatcgaa gtgaaatgga
     7381 attacgcgat ctgatctggt ggttcgcggg cctcgcgccc ggactgctgc tgggctggtg
     7441 gctgggcgcg cgcaagcgcc cggccacgac ccaggtcgag gcgacggcga caccgtcccc
     7501 gccgcaaccg caacggccgc ccgcacccgc gcaagccgcg cccgcagcaa cgcccgttgc
     7561 gcccgcaacg cccgcgcctg aagccgcgcc ggcggcgcac gccgccgaac cgcccgctcc
     7621 cgccgttcct gtatggtcgc cggacgtgca ggcgctgttc gacaagggcg agacgatcga
     7681 agcgatcaag aaaatccgca acaccctcgg cggcccggtc gcccgcaagg tcgcgcgcga
     7741 acacctgagc gaaggcgagt tccgcctgcc cgccgacatc cgcaagctcg ccgacgcgaa
     7801 caagaaactc gaagcgatcc gcctgctgtg cgatcagact catatggaca tgccgctggc
     7861 tcaacgtctg gttgagcact acgtcgccca tccaacccga tgaccgaaac cgaaacgcac
     7921 tacgacgcca accccaaggc ccacccgggc ctgcatgtga tcgccgcggt cgaagcggtc
     7981 aagggcgcgc tggcgctgag cgcggcgagc ggcctggaat tgctcggccc ggcgccgctg
     8041 cagcgctgga tcggcgagtt gatcaaacgc ttccatctgg accccgagca cggctcgctg
     8101 gcctggctcg cccacaccat cagcccgcat tcggtgcatc tggccgcggc ggtggtgctc
     8161 gcctacggat tgctgcacct ggtcgaagcc tggggcctgt ggaaggcgaa ggcctgggcc
     8221 tcgtggctcg gctgcctcgg cgccgcgctg tacctgccgt tcgacatcta cgcgatgttc
     8281 cgccaccccg gctggctggc caccgcggtg ctgatcatca acctgatcgt ggtgtgggtg
     8341 ctggcgcgcg acattctcaa gcggcggcag tgatctcgcg tcgaatccga cgaagtctgt
     8401 tgtgggaggg gcttcagccc cgatgctttt cgatcagatc gcgagaactc tcggcgcgat
     8461 ccaagctaaa tccctcgcaa tccccgtctt gatacgcccg ccgtatctgg cgaggtctgt
     8521 tgcgggaggg gcttgtgccc cgacgctttt cgatcagatc gcttcgaagc ttcatatgac
     8581 ctgatcgaaa agcatcgggg cacaagcccc tcccactaaa aacctcgaac ccgcccctga
     8641 tcggccgatt tgttagcgtc tgattaaacc gcaccgtgcc tgggtaccac cgcgatcggg
     8701 ctgcagtcac aggcatcgcg cgccgcgccg gtgtatggtt tccgggtcgc ggcgatcggc
     8761 cgcgatgcac gccgcgcgcc gcatcgcgcg acctgcgcat cacaacgatt cgatgcggac
     8821 gcgcgcaggc cgttgcgcgc gctgtcgatg tgctggcacg gctcattccc caccacgagg
     8881 aacgctcatg aagacctggt ccaagcctca gatccgcgaa atctcggtcg gctgcgaaat
     8941 caattcgtac tcctccggcg acctgttctg agcatgcccg cctctgccgt cgcaacgcgc
     9001 ccggggccgc gcagccattc gatggatcat cggtgatgcg catcctcgta ctcggtgcgg
     9061 cggccggagg cggctacccg cagtggaact gcaacacccc cggcagccag cgcgcctggc
     9121 gccaggaacc cggccatcaa cgccgcaccc aggccagcat cgcggtcagc gccgacaacg
     9181 agcgctggtt gctgatcaac gcctcgcccg acttccgcca gcagatcctc gcccagcccg
     9241 cgctgtggcc caaacgcgat ctgcgccact cgccgatcga agcggtgctg ctgaccagcg
     9301 gcgagatcga tcacatcgca ggattgctgt cgatgcgcga acgccagcgc ttcgacctgt
     9361 gggcgagcgc gcgcgtgctg gatgtgctga gccagaatcc gatcttcgat tcgctgcatc
     9421 ccgactacgt cgcgcgtaaa gcgctgagcc tggatacgcc gatcgaggtc gcaggccacg
     9481 acgcgccgct gggcctgcgg gtcaccgcct tcagcgtgcc cggcaaggtg ccgttgttca
     9541 tggagtcacg cgcgaacggc aatttgcaag gcggcgacga agaaacggtt ggcctggaaa
     9601 tcagcgacgg ccgcgaacgt ttcctctaca tccccggctg cgcggcgatg accgacgacc
     9661 tgcgccggcg cctgcacggc gcctcgctgg tgttgttcga cggcaccttg tggcgcgacg
     9721 acgaaatggt ccgcgccggc gtcggcagca agaccggcgc gcgcatgggc catatgaaca
     9781 tcgccggcga cggcggcgag gacggcggca cgctcgctgc attcgcgccg ctcgaagtac
     9841 ggcgcaaact gttcatccat ctcaacacca ccaacccgct gctcgacgat cactcgcccg
     9901 aacgcgctca agcgcgcgcg cacggctggg aagtcgccga ggacggcatg gagctgcagc
     9961 tgtgaacgca agcgcgaccc aggcgatcga caccgacttc atcggcgacg atgcgttgtt
    10021 gaccccggcg caactggaag cgcggctgcg cgcgatcggc gcggagcgct atcacgacaa
    10081 acaccccttc catcacctgc tgcacagcgg ccggttgaac cgcggccagg tccaggcctg
    10141 ggcgctcaac cgtttcgaat accagcgttg catcccgctc aaggacgccg ccctgctcgc
    10201 ccgcatcgag gacccgcaac tgcgccgggt ctggcgccag cgcatcgtcg atcacgacgg
    10261 cgagcgcgac ggcgacggcg gcatcgcgcg ctggctgcac ctgaccgatg cgctcggcct
    10321 ggaccgggcg acggtcgaat ccggccgcgc gctgctgccg gcgacgcggt tcgcggtgca
    10381 ggcgtatatc cacttcgtgc gcgaacgcag cctgctcgaa gcgatcgcct cctcgctgac
    10441 cgaactgttc gcgccgacca tcatcggcca gcgggtcagc ggcatgctgg ccaattacga
    10501 tttcgtctcg cgccagtcgc tggcctactt cgattcgcgc ctgcaccagg cgccgcagga
    10561 cgccaacttc gccctcgact acgtcaagcg ccacgccctc acccgcgcgc agcaggacgc
    10621 ggtgtgcgcg gcgctgcgat tcaaatgcga ggtgctgtgg tcgatgctcg atgccttgca
    10681 tctggcctat gtcgaaccgc gcttgatccc gccgggcgcg ttccgcccgg atgaagccgg
    10741 cccggacgag gccggcgcat gagcgcggcg atcgaagcca ccgcggtgcc gcgtttcccg
    10801 gccggggttc gcctgcagca cgaccgcgcg cgcgatcaat gggtgctgct cgcgcccgaa
    10861 cgcgtggtcg aactcgacga gatcgcccac gccgtgctcg cccgcgtcga cgccgccagc
    10921 gatgtcgagg ccatcgtgca ggcgctcgcg gccgagtacg gcgcggaacc tgcgcaagtg
    10981 catgacgacg tgatcgaact gttcgcgacc ttgctggaaa aacgcatgct cgccctgagt
    11041 acgccgatgc catgagcgtc gaagccgcca gcgtcgtcgc caccaccgga cttgcgccct
    11101 ccaaggcgcc ggcgcccgcg ccgccgctcg cggtgctgct ggaactgacc caccgctgcc
    11161 cgctgtcgtg cccgtactgc tccaacccgc tgcaactggt cggcatgcgc gaggaactgg
    11221 ccaccgccga ctggctgcgc gtactcgatc aggccgccga actcggcgtg ctgcaagtgc
    11281 attactccgg cggtgagccg accctgcgca aggacctgcc cgaactgctg cgccacgcgc
    11341 gcgcgctcgg cctgtactgc aacctgatca cctccggcgt cggcgtgacg cgcgaacggc
    11401 tgcaggagtt gcagcaggcc ggcctcgacc atctgcaact gagcatccag gacagccagg
    11461 ccgcgggcgc cgaccgcatc gccggttacg ccggcagcca cgaacgcaag ctcgcgctgg
    11521 cgcgctggtg cggcgaactc gatctgccgc tgaccctcaa cgccgtcgtg catcggcaca
    11581 acgccgaacg cgtcgcgcag atgatcgatc tcgcgctcga tctgggcgcg ggccggctcg
    11641 aagtcgcgca cacccagtac tacggctggg gcctgagcaa tcgcgccgcg ttgatgccca
    11701 cgcgcgcgca gctcgatgcg gtcaccgccg tggtcgagga cgcgcgccag cggctgcgcg
    11761 ggcggctgac catcgactac gtcaccccgg actattacgc gcgccggccc aaggcctgca
    11821 tgggcggctg ggcgcagcgc ttcgtcaaca tcaccccgga cggcaaggtg ctgccgtgtc
    11881 acgccgccga gaccctgacc gaattgcgct tcgactcggt gcgcgaccgc agcctgggcg
    11941 acatatggcg cgactccgac gcgttcgtgc gctaccgcgg caccgactgg atgcccgagc
    12001 cctgccgcgg ctgcgagcgc cgcgaaatcg actggggcgg ttgccgctgc caggcgctgg
    12061 cgctcagcgg ccgcgccgat acgctcgacc cggtgtgcga gaaatcgccc gatcacgcgc
    12121 gggttcgcgc cttggcgcaa gccgagtcgg ccgcgccggc gccggaattc atctaccgcc
    12181 gcctgcgcgc gacgggcgcc aaggccgcga cggactgacg tcgcttcggc aatccgcacc
    12241 ggcaaccgtc agtccagcag ctcgcgcagc cgttcgaaat aatcgccgct ccatttcgaa
    12301 tacagcgcgt cgtcgagatt gacgatgcga tagccatcgt cggcatcgaa atgggaaaac
    12361 acgcatcggc acacgcccag ggcgatccac acgatcgtcg cgcgatgcgc cgggtacgcg
    12421 gatgcatcgg acgccaccaa ccgcatgtcg ccgacgagcg attcgaacaa ggccgcgtcg
    12481 aacacgccgc gctcgaacag cccatggcag aacgtgcctt cgatctcgtc gtcgcggttg
    12541 ccgagcaaac gggcgacggc cgcgtcgatc cgcgggtcgc gcggcgcggc ttgcgtcggg
    12601 gtggttgaat tcatcgcggc ttcctttcga acacagaacg cgcggccgcg gccggccagt
    12661 tcaggccgca acgacgccat caggcatcgt aaccgtgcca cccgccccgc acgatgcaac
    12721 cgcgcagaca ccccgttgtt ccgcccggga cactgggccg ttcgaacagg cttgccgcgt
    12781 cgccgactgc gggcatactc gagcgaatcc ctcgcgcgcc acgatcagga accggccatg
    12841 cccgcctttc actgcaccgc ccgcctcggc ctcgccgcgc tgacgctcgc gctggccgga
    12901 tgcgccggcc cccaggccgt gcgcgcgccg cggccggtgg tggcttccga cgaagccgcc
    12961 aagggcttcc tgccgaccga cccgttgcgc ctggccgaag ccgacaccgc cgcgctgagc
    13021 gcgcgcatga gcaacggcga gctcagcagc gttcgcctga cccagggcta cctcgaccgc
    13081 atcgccgcgc tcgacgatgc cggcccgcag ctcaacgcgg tgatcgaact caaccccgac
    13141 gcgctcgccg aagcgcgcaa gctcgacgaa gaacgcaagg ccggccaact gcgcggcccg
    13201 ctgcacggca tcccggtgct gatcaaggac aacatcgacg ccacgccgat ggtcaattcg
    13261 gccggctcgc tggcgctggc cgagcaccgg cccaagaccg atgcgccgat cgtcgccgcg
    13321 ctgcgccgcg ccggcgcggt gatcctgggc aagaccaacc tcagcgaatg ggcgaatttc
    13381 cgctcgaccc attcgatctc cggctggagc ggccgcggcg gcctgacccg caatccctac
    13441 gtgctcgacc gcaccgcctg cggttccagc agcggcaccg gcgcggcgat cgccgcgagc
    13501 ctggccgcgg tcggcgtggg gaccgaaacc gacggcagca tcctgtgtcc ggcggcgatg
    13561 aacggactgg tcgggttcaa gccgacggtc gggctggtca gccgccaggg catcatcccg
    13621 atctcgcaca gccaggacac cgccggatcg atggcgcgca gcgtcgccga cgccgcgcag
    13681 ttgctcagcg tgctcgtatc ggccgaagcc ggcggcgaca gcgccgcgca ggccagcgcc
    13741 gacaagcgcc tggccgatta cgtcggcggc ctcgacggcg acgcgctgca cggcgcgcgc
    13801 ctgggcctgc tgcgcgaatc gggcgtcggc cagttgccgg cgatcgacgc cgcgctcgaa
    13861 cgcgcgctca agaccctgcg cgacgccggc gccaccgtgg tcgaggtcaa gatcgccacc
    13921 gccggccagt gggaccgcgc cgagggcgag gtgcttcgtt acgaattcaa ggacggcctg
    13981 gagcgctatc tgcgcgaaag cggcgcgccg gtgaagacgc tcggcgagct gatcgcgttc
    14041 aaccggacgc atgccgcgcg cgagcagcct tacttcggcc aggaattgtt cgaacaggcc
    14101 gacaagaagg gcagcctcaa ggacccggcc taccgcaagt tcgccgcgca ggcacgtcag
    14161 ctcgccggcc cgcagggcat cgacgcgaca ctcaagcggc acaagctcga cgcgctgatc
    14221 gcgccggcga cgaccccggc cttcatggtc gatccggtca acggcgatcc cttcggcggc
    14281 gccagttggg gcgcggccgc ggtcgccggg tatccgagcc tgaccgtgcc gatgggcgag
    14341 gcctccggcc tgccgatcgg cctggtgttc atgggcaagc gctggagcga cgcgcaactg
    14401 ctgtcgctgg gctacgcctt cgaacagctg accctggcac gcacgccgcc ggggtatcgg
    14461 gtgacgctga gtccctgagt tcgtcgccgt cgtcgacgcc gatcgcgcgg cctcgtccgt
    14521 agggatcgaa accagacgcg atcacccatg acgcgaagac aaaccttcgc gtgaaaccgc
    14581 acgcggcgtt ttcgcgcaac gatcacccgc gaccgttgtc atgtcagccc cctgtaggag
    14641 cggcgcaagc cgcgaccgcg acatcacgat tacgacgcaa gccggttccc gcgaccacga
    14701 cccgaaaacc aaaaacccgc ctcatcggcg ggttttcgct gcctgcatcc aaactcgcgt
    14761 tacgacaacc gcccaagccg cttccacacc tgcagcaaac cgatcaaatg caccacgccg
    14821 atgcccaggc agatcccgga actccacagc cagaaattca ggctgcgccc cggaaacacg
    14881 ctcatcatcg gcaccgcggc caccccgcgc agcagataca ccgcggtgac caggcacagc
    14941 accgtgcgca acaacggcaa gcggtgcagc gcacccgccg cggaaaacgc gtacaacgac
    15001 cagaccgtca gcaccgaggc gatcgccagc gtggcgacca ccggatgcca atgaccggcg
    15061 atcgaagcct gcgccatcca ttcgccggcc ccgaacgcgc gataccacgg cgcgccaaac
    15121 acgatgcagc ccagatgcaa caaggcggcg agcgcgctga gcgtgcccgc cgccaacaac
    15181 gcccgattac gttcgccgct catcgtcctt gcgaaccgat gaccgaccgc ccgtctcagg
    15241 ccggcgccgc gatctgcgcc tgcttgcgca cgatcagcat cgccacttcc agcgcctgtt
    15301 cgtagttcag gcgcggatcg accgtggaac ggtacgcgcg ctcgagatcg ctctcggtca
    15361 actcgcgcgc gccgcccagg cattcggtca cgtcttcgcc agtcagttcc agatgcacgc
    15421 cgcccaggcg cgtgccggcc gcggcatgca actcgaacga agtttcgatc tcggcgcgga
    15481 tgttgcggaa gcggcgggtc ttgtaaccgt tgctggtgct ctcggtgttg ccgtgcatcg
    15541 gatcgcacac ccacagcacg cggcggccgt cgcggcgcat cgcgtcgagc agcggcggca
    15601 gcttctcggc caccgcggtc gcgcccatgc gatggatgaa ggtcaaccgg cccggctcgt
    15661 cctcggggtt gagcaggtcg atcgtgcgca acagttggtc cggcgtgacc gacggaccga
    15721 ccttgagcgc gatcgggttg cgaatgccgc ggaagtattc ggcatgggcg ccgtcgaccg
    15781 cggcggtgcg catgccgatc cacgggtagt gggtgctgag gttgaagtgg ccccagtggc
    15841 gcggcacctg ccgggtcatc gactcttcgt acggcagcag cagcgcttcg tgcgaggtgt
    15901 agaaatccac gcggttgagg ttgtgcactt ccgaacccga caaggtctcc atgaagcgca
    15961 ccgcgtcgcc gatcgcgttg accatgcgcc ggtattcgtc ggccagcggc gaatgaccga
    16021 cccagctcag gttccagtac tcgggatggt gcaggtcggc gaaaccgccg tcgatcagcg
    16081 cgcgcacgaa gttcatcgtc atcgccgaac gcgcgtggcc cttgatcatg cgacgcgggt
    16141 cgggccggcg cgcggcctcg ttgaaggccg gcgcgttgac catgtcgccg cggtagctcg
    16201 gcaaggtcac cccgtcgatg gtctcggtgt cggccgaacg cggcttggcg tactggccgg
    16261 cgaaacgccc gacccgcacg accggcttgc gcatgccgtg gaccagcacc aggctcatct
    16321 gcagcaacac tttcagacgg ttggagatca cgtccgagga gcattggtcg aagctctcgg
    16381 cgcagtcgcc gccctgcagc aaaaatcgct tgccttcctg cgcctcggcc agttgctgct
    16441 tgagcgagag gatctcccac gaggtcacca acggcggcag ctgacgcagt tcctgcaacg
    16501 cggattcaag atcggccgcg tccggatagc tgggcaactg cagtgcggtg cgctcgcgcc
    16561 aggaggtcgg gctccagtcg gcgggcaggt tgacggcacg gaggttgctg ttgcgatcgg
    16621 aagcgctcat ttccttgatt ccagttggtg tcgcggtgtg tggatggttg cggtggatgg
    16681 gagggtgaag acgaagacgg cggaaaaacg acgaaggctt actgggttca acggccgcgg
    16741 aatgcggcat aggccgccca cagcgccagc acgatgaaac agatcaggct ccaggccggc
    16801 atggccagac cgaggaaggt ccagtccacg ttggcgcatt cgcccgaacc ggtcatgacc
    16861 ttcttgatca cgccggtgat cggcatcgca tcgagcatgt agttcaggcc cgggccacag
    16921 gccggaacct ggtccggcgg caggtgctgc aggcgcacgt gattgccggc gaccgcgatg
    16981 ccgcccagcg acgctagcag ggccaacacg ccgtagctgc gacgcccgcc gggcttcttg
    17041 ggcccgtgca acgcgccgag caggaacacc acgccgagcg cggcgaaggc cacgcgctgg
    17101 aagatgcaca gcgggcacgg ctcgaggtgc tggtagacct gcagatagac ggcatacgcg
    17161 agcaggcccg cgcaggccag gaaaccaagc agaaattgaa tccggaagga ggctttgaag
    17221 gggttcatgc tcacaccata cgggtctggg tcgggtcgtg ccaatgtcga atcggcatgt
    17281 attatcgcaa cgcggcattt cgtcgcagca acatcgactg cgcccgggga cgaaaagttg
    17341 ccgccccgtt cacgaccctg aaaaccccgc cagtgcatgg aatgaccgca ccctacaacg
    17401 gcgcgtcgct ttcgaccgca accgttgccg aagtaaccgt tgcgaaaacg caaaaacccc
    17461 ggccgaggcc ggggctttgc tggctgccgc cacgaccgcg aacggccatg gacggtagag
    17521 gcttgcgggt gattcgccac tgcgccggtc gcccggcgcg gcggatttac tcggccgcgg
    17581 cttgcggacg atcgaccagt tcgacgtagg ccatcggcgc attgtcgcca gcgcggaaac
    17641 cgcacttgag gatgcgcagg taaccgcccg gacgcgacgc gtagcgcggg ccgagttcga
    17701 cgaacaaggt gccgacggct tccttgtcgc gcaggcgcga gaacgccagg cggcgattgg
    17761 ccacgccgtc cttcttcgcc agggtgatga gcggctcggc gacgcgacgc agctccttgg
    17821 ccttcggcag ggtggtgcgg atgagaccgt gcttgatcag cgaggcggcc atgttggtga
    17881 acatggcgtc gcggtgggca ctggtgcggc tgaacttacg gccggatttc tgatggcgca
    17941 tgactgtgat tcctgatgaa tgttgaaacg gttggacttc gctgtcgcca tccaggcgtt
    18001 ggtgctttgg actgcgggtg gtccggaccg atcgttcctt gatcggctgg tcgcggagtt
    18061 ctgaatccgt cgacggggtg gtgcgtgctg cttgttacga attgcggtgt tgctgatgga
    18121 gcaagagccc acgcttcggg aaacctcggc gtggactctt gtcgttcccc ggccctgcgc
    18181 agtgcgcagg gcgttcgccc ggccgcgcgg cagtgccgcg cgagctaagc cgggctcacc
    18241 ccatcatgcc gtgcgaagcg atgccggccg gcggccagtt ttccagcttc atgccgagcg
    18301 acaggccgcg ctgagccagc acttccttga tctcggtaag cgacttcttg cccaggttcg
    18361 gggtcttgag cagctcgact tcggtcttct ggatcagatc gccgacgtag tagatgctct
    18421 cggccttgag gcagttggcc gaacgcacgg tgagctcgag atcgtcgatc gggcgcagca
    18481 ggatcggatc gatgccgctg gtggccggct tcgccgcacc gcggtcgcgg tgggtgaagt
    18541 cgccgaacac cgacagctga tcggtgagga tgtcggcggc ggtgcgcacg gcttcctcgg
    18601 cgtcgatcgt gccgttggtt tcgatgtcca gcaccagctt gtcgaggtcg gtgcgctgtt
    18661 cgacgcgcgc ggcttccacc gcgtaggcga cgcgacggac cggcgagaag ctcgcgtcca
    18721 gcatcagacg accgatcgcg cgggtttctt cgtccggacg acggcgcgaa gccgccggct
    18781 ggtagccgaa accgcgttcg atcttcagac gcatgttgat cgccgtgtcc ttggtcaggt
    18841 ggcagatcac gtggtcggtg ttgaggattt cgacgttgtg gtcggtcttg atgtcgccgg
    18901 cggtgacgat gccgggaccc tgcttggcca gcgacagcgt cgacgcgtcg ccggtgtgca
    18961 tgcggatggc gacgtccttg aggttcagca gaacctcaag cacgtcctct tccagacctt
    19021 cgaccgtggt gtactcatgc agcacgccat cgatttcgac ctcggtgatg gcgaaacccg
    19081 ggatcgacga cagcagcacg cgccgcagcg cgttgcccag cgtatggccg taaccgcgct
    19141 ccagcggctc gatcacgacc ttcgcgcgat tgccggtgag gcgttcgatc tgcggaccac
    19201 gcgggcgcag tacctgattg gcggtaaccg tcatgtttcg gtgtctccaa tgacctccac
    19261 cggggggcgg cgggaggctt tagctcttgg agccctctct taacgagaga gcggccggtg
    19321 cgcatggcgc accgacctgg gttgcgggtt ctccgccgga tcctgaggga cgccggcgga
    19381 tgccctgcac tattacttgc tgtacaactc gacgatcagc gcttcgttga tgtcggccgg
    19441 caggtccgca cgatccggaa ccgccttgaa cacgccgctg aacttcttgc tgtccacttc
    19501 gacccacgac ggcgacaggt ccatctgcga cgacacggtc agggattcct gcacgcgaag
    19561 ctgcttctgg gcgcgctcgg acaacgcgat cgcgtcgccg gccttgacct ggtacgacgg
    19621 aaggttgacc gacttgccgt tgacggtgac gccgcggtgc gagaccagct gacgggcagc
    19681 cggacgagtc acggcgaagc ccatgcggta gacgacgttg tccagacggg tttccagcaa
    19741 ctgcagcagg ttctcgccgg tgttgccctt cttggtcgag gccttcttgt agtagttgcg
    19801 gaactgacgc tccagcagac cgtagatacg cttgaccttc tgcttctcac gaagctgggt
    19861 ggcgtagtcg gacagcttgc ccttgcgggc ggtggggccg tgctgaccgg gcttctgctc
    19921 cagtttgcac ttcgagtcga gcgcgcgagc ggacgacttc agaccgagat cggcgccttc
    19981 gcgacgggcg agcttacagg tggggccaat ataacgagcc atttttcttc agctcctcag
    20041 acgcgacgct tcttcggcgg acggcacccg ttgtgcggga taggcgtcac gtcgatgatg
    20101 ttgatgatct tgtaaccgac gttgttcaag gaacgaacgg cggactcacg acccggaccc
    20161 gggcccttga tgcgcacttc cagcgacttg acgccgtagt cgagcgcagc acggccagcc
    20221 ttttcggctg ccacctgggc ggcgaacggg gtcgacttgc gggagccgcg gaaacccgcg
    20281 ccgcccgagg tcgcccacga gagcgcgttg ccctggcggt cggtgatcgt gatgatggtg
    20341 ttgttgaaag aagcgtggac gtgggcgata ccgtcggtga cgatgcgctt gatcttcttc
    20401 ttggtcttga ctgctgccgg cttggccatg gtctaggttc ccttacttct tgatggcctt
    20461 gcgcggaccc ttgcgggtac gtgcgttggt acgcgtgcgc tgaccacgca gcggcaagcc
    20521 gcggcggtga cgcaggccgc ggtagcagcc caggtccatc aaacgcttga tcgcaatacc
    20581 gacctcgcga cgcaagtcgc cttcgaccac gaacttgccg acttcggcgc gcaagcgctc
    20641 gacttcgggt tcggacaggt cacggatctt cgtggtcgaa gtcacacccg ccgtctggca
    20701 gatctgcttc gaacgggtac ggccgatgcc gaaaatgctt tgcaggccaa cccagacatg
    20761 cttctgggca ggcaaattaa cgcccgcaat acgcgccata aggcgatctc caactgattt
    20821 ggcggccgag acggattaat cccggcggag tgaactggaa attatatcta ggtctcgggt
    20881 taataggaag ccccgcggca cccaagggcg ccacggaacc acggcatggg gagtgtgccc
    20941 atgctccggc gacgagtctg aactggctga acaatgcgat gacccgccgt gcccagcccc
    21001 gcgcgctact ctggcgcgca gaacggtcct gactcacccg cgcgcgagac cgccgcgcga
    21061 gccgcccttc aagttcgctt tcttcaacag gctctcgtac tgatgcgaca tcagatgagc
    21121 ctggatttga gcgatgaaat ccatgatcac gaccaccacg atcaacagcg aggtaccgcc
    21181 gaagtagaac gaggtgccga gctgggtccg catgacctcc gggaggagac acacgatcac
    21241 caggtaaatt gcgccggccg cggtcaagcg ggtcagcacg ccgtcgacat agtccgcggt
    21301 ggccttgcca gggcgaatgc ccgggatcag cgcgcccgac ttcttgagat tgtcggcggt
    21361 ttcctgcgaa ttgaacacca gcgcggtgta gaagaacgcg aaaccgatga tcaggccggc
    21421 atacagaatc atgtggaccg gctcgcccgg gctgagccac tggctcaggc gctggaggaa
    21481 accggacacg ccgctgccgc tgttgccctg ggcgaaccag gtcgcggcgg tggcggggaa
    21541 catcacgatg ctggaggcga agatcgccgg gatcacgccc gacatgttga gcttcaacgg
    21601 caggaacgac gcctgattca tgtaggcgtt gcgaccgccc tggcgacgcg cgtagttgac
    21661 cgtgatccga cgctggccgc gttcgacgaa caccaccagg taggtgaagg ccaccaccag
    21721 accgacgacc aggatcgcca cgatcgggct catgtcgccg ttgcggatct gctcgaacat
    21781 gtggatcacc gcggccggaa ggccggcgac gatgcccgcg aagatgatca gcgaaacgcc
    21841 gttgccgacg ccgcgctcgg tgatctgctc gcccagccac atcaggaaca tggtgcccgc
    21901 cgtcaaggcg atcaccgcgg tcaggatgaa gcccatgccc ggtgcgtaca ccaccggcgt
    21961 gccatcgggc gccaggctcg actgcaggcc gttggcgatg ccccaggcct ggaagatcgc
    22021 cagcggaatc gcacccatgc gcgaccattg gttgatcttg cgacggcccg attcgccttc
    22081 cttctggatg gctttcaggc tcggcacgat ctgcaccagc aactgcacga tgatggacgc
    22141 cgagatgtac ggcatcacgt tcagcgcgaa caggctgaag cggtgcagag cgccaccgga
    22201 gaacatgttg aacatgtc
//
