LOCUS       NZ_JAHHZH010000003     23223 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Pseudomonas sp. MG-9 NODE_3_length_651067_cov_67.7801, whole genome
            shotgun sequence.
ACCESSION   NZ_JAHHZH010000003
VERSION     NZ_JAHHZH010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas sp. MG-9
  ORGANISM  Pseudomonas sp. MG-9
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 651067)
  AUTHORS   Lutfullin,M.T., Pudova,D.S., Lutfullina,G.F., Vologin,S.G.,
            Gogoleva,N.E., Shagimardanova,E.I., Sharipova,M.R. and
            Mardanova,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2021) Microbiology, Kazan Federal University, 18
            Kremlyovskaya, Kazan, Tatarstan Republic 420008, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2021
            Assembly Method                   :: SPAdes v. v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018729515.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 03:27:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,693
            CDSs (total)                      :: 5,604
            Genes (coding)                    :: 5,536
            CDSs (with protein)               :: 5,536
            Genes (RNA)                       :: 89
            rRNAs                             :: 8, 9, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 6, 8 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 25 of 68
            Pseudo Genes (incomplete)         :: 48 of 68
            Pseudo Genes (internal stop)      :: 11 of 68
            Pseudo Genes (multiple problems)  :: 11 of 68
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:31:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 318919
            Orig. end                         :: 342142
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHHZH010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23223
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..23223
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23223
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13223]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13223
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    82..97
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.5"
                     /tool="antismash"
     misc_feature    840..855
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.49"
                     /tool="antismash"
     gene            complement(1786..3513)
                     /locus_tag="KKQ10_RS09725"
                     /old_locus_tag="KKQ10_09725"
     CDS             complement(1786..3513)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007904105.1"
                     /locus_tag="KKQ10_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09725"
                     /product="autotransporter assembly complex family protein"
                     /protein_id="WP_215500951.1"
                     /transl_table=11
                     /translation="MKFPGRFTSGVLMLLTSCAALAQSELDVRIKPSNDELKANIEGYI
                     GSLGDRDEEALLRFSRGAEEQARKAAQALGYYQPQIDSDVKGGEKPRLVLNIDPGEPIR
                     LRNVTIRVGGPAAALKSFRVPSSDMLKSGAVLNHGRYEDAKRLIQNQASRFGFFSGHFT
                     SQKLMVDPRAGVADVELIYESGPRYALGSVSFEGDTPFDEDLLQRMVPFKAGDPYDSEL
                     IAELNRDLQSSGYFEGVRVDAAPTAAKNDVIPVDVKLDTRKPRTMGLGLGYSTDVGPRI
                     KANWTRHWVNPQGDSYGWEAELSAPRQNVGLFYDIPLDPPLTDKLRWAGGYQYEDIDGS
                     DTLSKLLTFGPEWHSKLPSGWQRVISLKWQREEYQLGDDSGLSTLLMPGISYSYLKSDN
                     RIDPHHGYRLTFESKVAKEGLGSDNNLLYGTALIKGLTTVFDNHRFLGRVQVGGSATNG
                     YNSVPPSLRFFAGGDQSVRGYDYQSLSPENSKGDRIGGRYMVAGSVEYQYSIAEKWRIA
                     TFVDQGNSFNKLELPNLKTGVGIGVRWVSPVGPIRLDLAHALDDDGGIRLHFSMGPEL"
     misc_feature    complement(3557..3571)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.78"
                     /tool="antismash"
     gene            complement(3580..4230)
                     /locus_tag="KKQ10_RS09730"
                     /old_locus_tag="KKQ10_09730"
     CDS             complement(3580..4230)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018925466.1"
                     /locus_tag="KKQ10_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09730"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_215500952.1"
                     /transl_table=11
                     /translation="MPETQTAIADIHMLDRGYSREARSLLYQAYRHEPTFGYLFEAERP
                     GYEQRVRATVRELVKQHFLQDLPAIGLLVNDRLIGIALIAPPQRRLGITESWAWRLRMV
                     LSTGFRCTRRYLEYHDAVAACVPSDSVHMLPLLGVHPQFQGKHFGEQLLTAVHNWCAVD
                     ESSQGVVLDTGNPRYLEFYKRQGYEEIGEVAVGPVREHVFFHANPQVLQTATA"
     misc_feature    4310..4325
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.22"
                     /tool="antismash"
     gene            4533..5345
                     /gene="xthA"
                     /locus_tag="KKQ10_RS09735"
                     /old_locus_tag="KKQ10_09735"
     CDS             4533..5345
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008311 - double-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="xthA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_251235.1"
                     /locus_tag="KKQ10_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09735"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_127652070.1"
                     /transl_table=11
                     /translation="MKIVSFNINGLRARPHQLAALIEKHQPDVIGLQETKVHDDQFPLE
                     EVRALGYHVYFHGQKGHYGVALLSRNEPIAVHKGFATDEEDAQRRFIWGTFADANGVPV
                     TIMNGYFPQGESRDHPTKFPAKQRFYSDLQTLLESQFHNEQPLVVMGDVNISPEDRDIG
                     IGPDNMKRWLKTGKCSFLPEEREWMARLKNWGLTDSFRHLNPDVSDMFSWFDYRSRGFE
                     DEPKRGLRIDVILASHGLLPRVKDAGVDYELRGMEKPSDHAPIWLELA"
     misc_feature    4534..4548
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            5508..6842
                     /locus_tag="KKQ10_RS09740"
                     /old_locus_tag="KKQ10_09740"
     CDS             5508..6842
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019648445.1"
                     /locus_tag="KKQ10_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09740"
                     /product="phosphate ABC transporter substrate-binding/OmpA
                     family protein"
                     /protein_id="WP_215500953.1"
                     /transl_table=11
                     /translation="MTLRVLFVFVLSAWLTVSAAILPIPENGPALRIQGSNTIGADLGP
                     ALVEGFLQEQGLLKIHRENPDTANEQHIVGQTAQGKRVVIEVAAHGSSTGFTALKSAAA
                     DLAAASRPIKDSELLSLQALGDMKSPEAEQVIAIDGLAIILHPDNPLQQLDTGQLARIF
                     AGEVKTWEDLGGRGGAIHLYARDDQSGTYDTFKELVLSRRGKSLSATAKRFESSEQLSD
                     AVSSDAQGIGFIGLPYVRQAKAVAIADGASQSMLPLNSLIATEDYPLSRRLFFYLPPTS
                     QNPWASALVAFAQSPQGQKIVAANGFISQTIHAMTVTPNALMPEGYQSLSRHAQRLTVN
                     FRFEEGSASLDNKARQDLARVLDYIKRHDKTERAVTLVGFGDEKDDPARADLLSKLRAM
                     AVRRELVKNGVVLREVRGFGALMPVAANSADEGRIKNRRVEVWVY"
     gene            complement(6969..8198)
                     /locus_tag="KKQ10_RS09745"
                     /old_locus_tag="KKQ10_09745"
     CDS             complement(6969..8198)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009044614.1"
                     /locus_tag="KKQ10_RS09745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09745"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_003223710.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-19, bitscore:
                     65.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.5e-20, bitscore:
                     68.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.5e-34, bitscore:
                     113.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFAYSPKVQELRERVTAFMDTYVYPAEAVFERQVAEGDRWQPTA
                     IMEELKAKAKAEGLWNLFLPESELGAGLTNLEYAPLAEIMGRSLLGPEPFNCSAPDTGN
                     MEVLVRYANEEQKQRWLEPLLRGEIRSAFAMTEPDVASSDATNMAARAVRDGDEWVING
                     KKWWTSGACDPRCKILIFMGLSNPDAPRHAQHSMILVPVDTPGVKIVRPLPVFGYDDAP
                     HGHAEVLFDNVRVPYENVLLGEGRGFEIAQGRLGPGRIHHCMRSIGMAERALELMCKRS
                     VSRTAFGKPLARLGGNVDKIADSRMEIDMARLLTLKAAYMMDTVGNKVAKSEIAQIKVV
                     APNVALRVIDRAIQIHGGAGVSNDFPLAYMYAMQRTLRLADGPDEVHRAAIGKFEIGKY
                     VPKEMLRSGH"
     misc_feature    8288..8301
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            8370..9305
                     /locus_tag="KKQ10_RS09750"
                     /old_locus_tag="KKQ10_09750"
     CDS             8370..9305
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1125: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007917233.1"
                     /locus_tag="KKQ10_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09750"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_127652072.1"
                     /transl_table=11
                     /translation="MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLR
                     ETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLLRVSVQESRIFNPAQAVKTYRISMT
                     DLTEAVILPPLFQRLRRLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRH
                     VKLMEDRYVCAMRKGHPLAGKEKLSLDDYLSLTHIHISSRRSGLGYVDLALGKMGIQRK
                     IALRSQHYLMASQVMQQTDMVMTVPERFARRNDLHAFNLPVNDVPPLETHLYWHESTDQ
                     DPANRWMREQIIELCQQVAAQEKKLDKQVV"
     misc_feature    9347..9361
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    complement(9347..9361)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.12"
                     /tool="antismash"
     gene            9456..9857
                     /locus_tag="KKQ10_RS09755"
                     /old_locus_tag="KKQ10_09755"
     CDS             9456..9857
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007980992.1"
                     /locus_tag="KKQ10_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09755"
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_127652073.1"
                     /transl_table=11
                     /translation="MSSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPR
                     DKVSLKLILRGKRIGFSLAECRELIELYDPSSGNTKQLNSMLAKISERREQLEQQLLDI
                     EQMKLELDTAEERCVQALEQTLKSQQPVQ"
     gene            10001..10900
                     /locus_tag="KKQ10_RS09760"
                     /old_locus_tag="KKQ10_09760"
     CDS             10001..10900
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015094354.1"
                     /locus_tag="KKQ10_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09760"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_215500954.1"
                     /sec_met_domain="HMGL-like (E-value: 3.7e-55, bitscore:
                     182.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPSHVRLIEVGPRDGLQNEAQPISVADKVQLVDALSAAGLSYI
                     EVGSFVSPKWVPQMAGSAEVFAQIQRKPGVTYGALAPNLRGFEDALAAGVKEVAVFAAA
                     SEAFSQRNINCSISESLARFAPIMEAAKQHGVTVRGYVSCVLGCPYEGTVAPEQVAMVA
                     RELYAMGCYEVSLGDTIGTGTAGATRRLFEVVSAQVPREKLAGHFHDTYGQAMANIYAS
                     LLEGIAVFDSSIAGLGGCPYAKGASGNVATEDVVYLLNGLGIETGIDLDALIAAGQQIS
                     AVLGRPSGSRVAKARNAQ"
     gene            complement(11529..13223)
                     /locus_tag="KKQ10_RS09765"
                     /old_locus_tag="KKQ10_09765"
     CDS             complement(11529..13223)
                     /NRPS_PKS="Domain: AMP-binding (29-462). E-value: 7.2e-99.
                     Score: 323.1. Matches aSDomain:
                     nrpspksdomains_KKQ10_RS09765_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008020899.1"
                     /locus_tag="KKQ10_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09765"
                     /product="AMP-binding protein"
                     /protein_id="WP_215500955.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-107, bitscore:
                     353.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQPSANPPRSYTRGAQDKALLAMTIGQKFDQTVAQYPDGEALVV
                     RHQQLRYSWRQLADAVDLHARALLALGLQAGDRLGIWAPNCAQWCITQIATAKIGVILV
                     NINPAYRSSELEYVLKQSGCQWLVCAGAFKSSNYHAMLQGLVPELAEQSIGQLRCERLP
                     ELRGVISLDAQPPSGFLPWSQLADLAAGVSPQQLHERSDSLHFDQPVNIQYTSGTTGFP
                     KGATLSHYNILNNGYMVGESIGLTPSDRLVIPVPLYHCFGMVMGNLGCITHASTMIYPS
                     DAFDPLLTLQTVAEEQATGLYGVPTMFIAMLDQPLRADFDLSSLRTGIMAGATCPIEVM
                     RRVISEMHMSEVQIAYGMTETSPVSLQTGPNDELELRVTTVGRTQPQLESKIIDEAGDL
                     VPRGTIGELCTRGYSVMLGYWNNPQATAEAIDEAGWMHTGDLASMNDEGYVNIAGRNKD
                     MIIRGGENVYPRELEEFFFTHPAVADVQVIGIPCSRYGEEIVAWIKFHPGHNASELELQ
                     TWCKERIAHFKTPRYFKFVEEFPMTVTGKIQKFRMREISIEELKALH"
     aSDomain        complement(11838..13136)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KKQ10_RS09765_AMP-binding.1"
                     /evalue="7.20E-99"
                     /label="KKQ10_RS09765_AMP-binding.1"
                     /locus_tag="KKQ10_RS09765"
                     /protein_end="462"
                     /protein_start="29"
                     /score="323.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FDQTVAQYPDGEALVVRHQQLRYSWRQLADAVDLHARALLALGLQ
                     AGDRLGIWAPNCAQWCITQIATAKIGVILVNINPAYRSSELEYVLKQSGCQWLVCAGAF
                     KSSNYHAMLQGLVPELAEQSIGQLRCERLPELRGVISLDAQPPSGFLPWSQLADLAAGV
                     SPQQLHERSDSLHFDQPVNIQYTSGTTGFPKGATLSHYNILNNGYMVGESIGLTPSDRL
                     VIPVPLYHCFGMVMGNLGCITHASTMIYPSDAFDPLLTLQTVAEEQATGLYGVPTMFIA
                     MLDQPLRADFDLSSLRTGIMAGATCPIEVMRRVISEMHMSEVQIAYGMTETSPVSLQTG
                     PNDELELRVTTVGRTQPQLESKIIDEAGDLVPRGTIGELCTRGYSVMLGYWNNPQATAE
                     AIDEAGWMHTGDLASMNDEGYVNIAGRNKDMIIR"
     CDS_motif       complement(11937..12023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KKQ10_RS09765_0002"
                     /evalue="3.30E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="KKQ10_RS09765"
                     /protein_end="429"
                     /protein_start="400"
                     /score="32.2"
                     /tool="antismash"
                     /translation="PRGTIGELCTRGYSVMLGYWNNPQATAEA"
     CDS_motif       complement(12537..12590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KKQ10_RS09765_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="KKQ10_RS09765"
                     /protein_end="229"
                     /protein_start="211"
                     /score="17.9"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
     gene            13554..14717
                     /locus_tag="KKQ10_RS09770"
                     /old_locus_tag="KKQ10_09770"
     CDS             13554..14717
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_250705.1"
                     /locus_tag="KKQ10_RS09770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09770"
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="WP_127652077.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-39, bitscore:
                     130.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.5e-28, bitscore:
                     94.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.4e-43, bitscore:
                     141.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPSLNFALGETIDMLRDQVQSFVADQIAPRAAQIDHDNLFPAD
                     MWRKFGDMGLLGITVPEEYGGAGLGYLAHVVAMEEISRGSASVALSYGAHSNLCVNQIN
                     RNGNHEQKSQYLPKLISGEHVGALAMSEPNAGSDVVSMKLRADKRGDRFVLNGSKTWIT
                     NGPDANTYVIYAKTDLEKGPHGITAFIVERDWKGFSRSNKFDKLGMRGSNTCELFFDDV
                     EVPEENILGVLNGGVKVLMSGLDYERVVLSGGPTGIMQSCMDLIVPYIHDRKQFGQSIG
                     EFQLIQGKVADMYTQLNASRAYLYAVAQACERGETTRKDAAGVILYTAERATQMALDAI
                     QILGGNGYINEFPAGRLLRDAKLYEIGAGTSEIRRMLIGRELFNETK"
     gene            14822..16426
                     /locus_tag="KKQ10_RS09775"
                     /old_locus_tag="KKQ10_09775"
     CDS             14822..16426
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010458780.1"
                     /locus_tag="KKQ10_RS09775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09775"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_127652078.1"
                     /transl_table=11
                     /translation="MILHTQLNPRSAEFAANSAAMLEQVDALHTLLAQVAQGGGAKAQE
                     RHTSRGKLLPRERINRLLDPGSPFLEISQLAAHAVYGEDVPAAGVIAGIGRVEGVECMI
                     VANDATVKGGSYYPLTVKKHLRAQTIAQQNRLPCIYLVDSGGANLPRQDEVFPDREHFG
                     RIFFNQANMSAMGIPQIAVVMGSCTAGGAYVPAMADEAIMVRNQATIFLAGPPLVKAAT
                     GEVVSAEDLGGADVHCKISGVADHYAESDEHALALARRSVANLNWRKLGEVQQRAPIAP
                     LYASDELYGVVSADAKQPFDVREVIARLVDGSVFDEFKALFGTTLVCGFAHLHGYPIAI
                     LANNGILFAEAAQKGAHFIELACQRGIPLLFLQNITGFMVGQKYEAGGIAKHGAKLVTA
                     VACAKVPKFTVIIGGSFGAGNYGMCGRAYDPRFLWMWPNARIGVMGAEQAAGVLVQVKR
                     EQAERSGQGFTAEQETEIKQPILDQYEEQGHPYYSSARLWDDGVIDPAQTRDVLALALS
                     ASLNAPIEPSRFGVFRM"
     gene            16440..17255
                     /locus_tag="KKQ10_RS09780"
                     /old_locus_tag="KKQ10_09780"
     CDS             16440..17255
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (15-255). E-value: 1.7e-44. Score:
                     143.9. Matches aSDomain:
                     nrpspksdomains_KKQ10_RS09780_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010458779.1"
                     /locus_tag="KKQ10_RS09780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09780"
                     /product="gamma-carboxygeranoyl-CoA hydratase"
                     /protein_id="WP_215500956.1"
                     /transl_table=11
                     /translation="MSDFNTLELQSDPRGFATLWLNRAEKNNAFNAEMIRELILALDKV
                     ASDASLRFLLVRGRGKHFSAGADLAWMQQSAELDYHTNLDDARELAELMYNLAKLKIPT
                     LAVVQGAAFGGALGLISCCDMAIGTDDAQFCLSEVRIGLAPAVISPFVVQAIGERAARR
                     YALTAERFGGQRAREIGLLSESYPAVELDQAVEQWIDNLLLNSPAAMRASKDLLREVGN
                     GALTPALRRYTENAIARIRVSPEGQEGLRAFLQKRAPSWQAATTPKEPR"
     aSDomain        16485..17204
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KKQ10_RS09780_ECH.1"
                     /evalue="1.70E-44"
                     /label="KKQ10_RS09780_ECH.1"
                     /locus_tag="KKQ10_RS09780"
                     /protein_end="255"
                     /protein_start="15"
                     /score="143.9"
                     /tool="antismash"
                     /translation="FATLWLNRAEKNNAFNAEMIRELILALDKVASDASLRFLLVRGRG
                     KHFSAGADLAWMQQSAELDYHTNLDDARELAELMYNLAKLKIPTLAVVQGAAFGGALGL
                     ISCCDMAIGTDDAQFCLSEVRIGLAPAVISPFVVQAIGERAARRYALTAERFGGQRARE
                     IGLLSESYPAVELDQAVEQWIDNLLLNSPAAMRASKDLLREVGNGALTPALRRYTENAI
                     ARIRVSPEGQEGLRAFLQ"
     gene            17255..19204
                     /locus_tag="KKQ10_RS09785"
                     /old_locus_tag="KKQ10_09785"
     CDS             17255..19204
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007961120.1"
                     /locus_tag="KKQ10_RS09785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09785"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_215500957.1"
                     /sec_met_domain="ATP-grasp (E-value: 5.9e-11, bitscore:
                     37.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.2e-14,
                     bitscore: 47.0, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVLTTLLVANRGEIACRVMRTAKALGLTTVAVHSATDREARH
                     SREADIRVDLGGSKAADSYLQIDKLIAAAKASGAQAIHPGYGFLSENAGFARAIEQAGL
                     IFLGPPASAIDAMGSKSAAKALMETAGVPLVPGYHGEAQDLDTFRDACERIGYPVLLKA
                     TAGGGGKGMKVVEDVSQLAEALASAQREAQSSFGDSRMLVEKYLLKPRHVEIQVFADQH
                     GNCLYLNERDCSIQRRHQKVVEEAPAPGLPPELRRAMGEAAVRSAQAIGYVGAGTVEFL
                     LDARGEFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALPITQDQVPLNGHAIE
                     VRLYAEDPSNDFLPATGRLQLYRESAAGPGRRVDSGVEEGDEISPFYDPMLGKLIAWGE
                     DREQARLRLLSMLDEFAIGGLKTNINFLRRIIAHPAFAAAELDTGFIPRYQEQLLPAPG
                     ELGDGFWHAAAQAFAQSLPGAVRADDLSSPWALNSGLRAGLPAEITLHLSCEGQDRALT
                     LSAASNTRLSGEALWVEHDGVRRTLRAIRQGDSLYLQWDGELRRIETYDPINAVEASHS
                     HQGGLTAPMNGSIVRVLVEAGQSVEAGAQLVVLEAMKMEHSIRAPHAGVIKALYCQEGE
                     MVGEGSALVELEAV"
     gene            complement(19245..19904)
                     /locus_tag="KKQ10_RS09790"
                     /old_locus_tag="KKQ10_09790"
     CDS             complement(19245..19904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007917250.1"
                     /locus_tag="KKQ10_RS09790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09790"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_215500958.1"
                     /transl_table=11
                     /translation="MDKWIELVKAKMSELKITQTELGERVGMSQGGIGHWLNKRREPGI
                     TQMNRVLHALGMDFLEVVLVIREPQEAADDEMPLAQKYNPYFRYPVSDWRTSCEIRESA
                     TTAYAPAHGKQRFELTDYHARGAAFWLTVTGDSMTAPTGQSIAEGMLILVDPEVEAVPG
                     KLVIAQWQDSEEAIFRKLDEEGGQRYLVPLNPTWPKALFTDECRIIGVVVQATARF"
     gene            20035..20373
                     /locus_tag="KKQ10_RS09795"
                     /old_locus_tag="KKQ10_09795"
     CDS             20035..20373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223691.1"
                     /locus_tag="KKQ10_RS09795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09795"
                     /product="DUF3077 domain-containing protein"
                     /protein_id="WP_127652082.1"
                     /transl_table=11
                     /translation="MNISSEDLPDLQMDTTFTSPQGNAAAQRALDYYLKPAVSEPEVEE
                     RFFDVKRHLSGEEALVHASDLLRCAAATAFKAAENLQGASRDLAFSVVHMVDMARAMVD
                     HSIDGEQL"
     misc_feature    20406..20423
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    complement(20437..20451)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    complement(20438..20453)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    20441..20456
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.0"
                     /tool="antismash"
     misc_feature    complement(20443..20456)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.52"
                     /tool="antismash"
     misc_feature    complement(20443..20457)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    20444..20457
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.06"
                     /tool="antismash"
     misc_feature    complement(20444..20459)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 26.61"
                     /tool="antismash"
     misc_feature    complement(20446..20459)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.32"
                     /tool="antismash"
     misc_feature    20450..20463
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.24"
                     /tool="antismash"
     misc_feature    complement(20577..20593)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.12"
                     /tool="antismash"
     misc_feature    20715..20730
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    complement(20715..20733)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.71"
                     /tool="antismash"
     misc_feature    complement(20827..20840)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.76"
                     /tool="antismash"
     misc_feature    complement(20830..20844)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.95"
                     /tool="antismash"
     gene            20855..22006
                     /locus_tag="KKQ10_RS09800"
                     /old_locus_tag="KKQ10_09800"
     CDS             20855..22006
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223690.1"
                     /locus_tag="KKQ10_RS09800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_09800"
                     /product="M14-type cytosolic carboxypeptidase"
                     /protein_id="WP_215500959.1"
                     /transl_table=11
                     /translation="MTVAKSSFDISANFDSGNIQVIDLSNPLNPVLAIRPDTRSAHFQW
                     FHFKASGLHVHQEHWFRLVNASQSSYNKAWTGYQAVASYDHVNWFRIPTSFEGDSLRFC
                     LEAEQTHAWFAYFEPYSRGRHDWLIEQALTKAGTELLATGKSVEGRDIQLLRKGSGAEG
                     RRKVWIIAQQHPGEHMAEWFMEGVIERLERHEDPVLNKLLASADLYLVPNMNPDGAFHG
                     HLRTNAMGQDLNRAWQNASQEVSPEVLFVQQQMEKYGVDLFLDVHGDEEIPHVFTAGCE
                     GNPGYTPRIEKLEEHFRTHLKHTTKDFQTQYGYTRDEPGQANMTLACNAVGEKYDCLSL
                     TLEMPFKDHDDHPDKETGWSGKRSKQLGKDVLTTIADMVNTLR"
     misc_feature    complement(22694..22710)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
ORIGIN
        1 tgcccttcag atcgatcttc gcccgctgcg cactgtcgag gctggcatcg aggttgaggc
       61 tttgcaggcg attgtcctgg aacgccagtt gcgaaccttg caaatcgagc ttgccttgcg
      121 gcgccttcag cgtaccggcg acgttgacct gcccagtgac ctgtccgcgc agttgcggcc
      181 agagttgagc cagccgcgcc agcttgatgt cgatctgccc ggtgagtttc tgttgcaggc
      241 tgcccttgcc gttgatgctg ttgtcgccta agcggatttg cagggcgttg aggttccact
      301 gttcgccgga accatcagcc ttggcttgca ggatcgccgg ttgaccacgc aacttgccct
      361 tgaggtcgag gtcggcgctg aggctcaggc gctcgttctt catctcgccc tggcttttca
      421 gcagcccggc caaggtgccc ggcaactccg cgacccagta cgccgggttc agcgccgaca
      481 gctccagcgc ggtgtcccag gcgatgccgt cggcgaactg cacgttcaca tgaccttcgg
      541 ccttgccctg cccggcttcc attttcagtt gcggcaaggc gatctgtttc aggctgccgc
      601 tgaacggact gctcaggctg aacgcccccg ccggaccgtc cagtgcggcg gcaaagttac
      661 cgatgtactg accgtcggtg taggaaactt cgccggtgaa ggtgcgcaac gcgacttgcg
      721 gctcgtcgat ttcgttatag agccgatgcc acgggaaatc ctgccagttg atgttggctt
      781 gcgcggtaag gcctttgctc cagtcgacac tgccagtaag tttgagactc tgcttgtcgt
      841 tggccgtcag gtcgaggccg gcgatctgcg cgccgctggc gtccaccttg ccgttgagca
      901 gcagcgccac cgggcctttg tcggcgggca gcgtggcatt gccgcttaac tgataaccgt
      961 ttttcagatc gccttcgccg gtcaacacca attgattgag ttgcaacgtg tccggcagat
     1021 cggcgctcgg tttgaaggcc tccgaggtga tgcgcacctt ggccggcagg ttttccgcca
     1081 gcggttgtag ctcgccgctc aactggccgt cgaggtaacc gtggctgtcg gcgtgcaggt
     1141 tgagggtttt cagcagatcg ccgtcaacct tcagcgccag tgtccagggg ccggtgcccg
     1201 gcgacggcag ggtcaggtcg ccggcaatgt tcagcggcca gttgccggtc ggttgcagca
     1261 ggccggagag gttcaggctc agatcgtcgc gttgcagttt gacgctgtcg atctgcaggc
     1321 cctgggcagt ccagtgcgcc gccaattgca ggcccttgag ctgctcgctg ccattgaaca
     1381 acaggctgcc gacctgcacg tcacccagtt cgatggccac cggcaattgc agatccggca
     1441 gtttgatcgg gccgctgtcg gtggtttctt cactcggcgg gaattgcaga atgacctgat
     1501 ccgccttgag ctgttcgatg cacagggtca tgcgggtcag gcacagcggc gaccaggcga
     1561 agatcggctt gttcagctcg acccggctgc tgtcctgctg ccacagcaga tgatcggcgc
     1621 tccactgccc gccgaggcga ccctggaaat tctccacgct caggccgggc accaggccca
     1681 gcgcccaacg actgcccgcc tgcgttccga gtaccgcgct gatgctcaat acaatcaaca
     1741 acagcaacgc cagcagcgtc agtgccgcta ttttcaaacc acgcttcaca gctcaggccc
     1801 catggaaaag tgcagccgga tgccgccatc gtcgtccagc gcgtgggcca ggtcgaggcg
     1861 gatcggcccc accggcgaga cccagcgcac accgataccg accccggtct tgaggttcgg
     1921 cagttcgagt ttgttgaaag agttgccctg gtcgacgaag gtcgcgatac gccacttctc
     1981 ggcaatcgaa tattgatact cgacgctgcc ggccaccatg tagcgcccgc cgatgcggtc
     2041 gcccttggag ttctccgggg acaagctctg gtagtcgtaa ccacgcacgc tctgatcacc
     2101 accggcaaag aagcgcagcg atggcggtac cgagttgtag ccgttggtgg cgctgccgcc
     2161 gacctgcacc cgcccgagga agcggtggtt gtcgaatacg gtggtcaggc ctttgatcaa
     2221 cgccgtgcca tagagcaggt tgttgtccga gccgaggcct tccttcgcca ctttgctttc
     2281 aaaggtcagg cgatagccgt ggtgcgggtc gatgcgattg tcgcttttga ggtacgaata
     2341 gctgatgccg ggcatcaaca aggtactgag gcccgagtcg tcgccgagct ggtattcctc
     2401 gcgctgccat ttcaacgaga tgacccgctg ccagccgctg ggcagcttgc tgtgccattc
     2461 cgggccgaac gtcagcagct tgctcagggt gtcggagccg tcgatgtctt catattgata
     2521 gccgccggcc caacgcagtt tgtcggtcag aggcgggtcg agcgggatgt catagaacag
     2581 cccgacgttc tgccgcggcg ccgacaattc ggcctcccag ccatagctgt cgccctgcgg
     2641 attgacccag tggcgggtcc agttggcctt gatccgtggg ccgacgtcgg tggaataacc
     2701 gaggcccagg cccatggtgc gcggcttgcg cgtgtcgagt ttgacgtcca ccggaatcac
     2761 gtcgttcttg gctgccgtcg gtgcggcatc gacgcgcacg ccttcaaaat agccactcga
     2821 ttgcaggtcg cggttgagtt cggcgatcag ctcggagtcg tacggatcgc ccgccttgaa
     2881 cggcaccatg cgctgcaaca ggtcttcgtc gaacggtgtg tcgccctcga aactgacgct
     2941 gcccagcgca taacgcgggc cgctttcgta gatcagttcg acatcggcca ccccggcgcg
     3001 aggatcgacc atgagtttct ggctggtgaa gtggccgctg aaaaaaccga agcgcgaggc
     3061 ctggttctgg atcaggcgtt tggcgtcttc ataacgccca tgattgagca cggcgccgga
     3121 cttgagcatg tcgctgctcg gcacacgaaa ggatttgagg gcggcggcag gcccgccgac
     3181 gcggatggtg acattgcgca gacgaatcgg ttcgccggga tcgatgttca gcaccaggcg
     3241 cggcttttcg ccgcccttca catcactgtc gatctgcggc tggtaataac ccaaggcctg
     3301 cgcggctttg cgcgcctgct cctcggcccc gcgactgaag cgcagcaagg cttcttcatc
     3361 acgatcgccg aggctgccga tatagccttc tatattggcc ttcagttcat cgttggacgg
     3421 tttgatccgc acgtccaatt cactttgcgc cagcgccgca cagctggtta acagcatgag
     3481 cacgccactg gtaaatcttc ctggaaactt cataggcgcg gatgctatca cgggcttggg
     3541 agcgtgatag aacaggaaat gtccgaaaaa gttcgacgac taagccgttg cagtttgtaa
     3601 cacctgcgga ttggcgtgga aaaacacgtg ctcgcgcacc gggccgacgg ccacttcacc
     3661 gatctcttcg tagccttggc gtttatagaa ttccaggtag cgcggattac cggtgtcgag
     3721 caccacgcct tgcgaacttt cgtccaccgc gcaccagttg tgcaccgccg tcagcaactg
     3781 ctcgccgaag tgtttgccct gaaactgcgg atgaacgccc aacagcggca acatgtgcac
     3841 cgaatcgctg ggcacgcacg cggccaccgc atcgtgatat tccagatagc gccgggtgca
     3901 gcgaaaaccg gtgctgagca ccatgcgcag gcgccacgcc caactctcgg tgatgcccaa
     3961 ccggcgctgc ggcggcgcga tcagggcgat gccgatcaac cgatcgttga ccaacaggcc
     4021 gatggccggc agatcctgca gaaaatgctg tttgaccagt tcgcgcacgg tggcccgcac
     4081 acgctgctca tagcccggcc gctcggcctc gaacaggtaa ccgaaggtcg gctcgtgccg
     4141 gtaggcctga tacagcagtg atcgggcttc acgcgagtaa ccgcggtcga gcatgtggat
     4201 gtcggcaatg gcagtctggg tttcaggcat gacgatgatg ctccccgggg cgcgtgcaaa
     4261 gggcggcgct cttgttggta cgaacctttt gatggtggcg cagttcccca caggtataga
     4321 ccaacccggg atcttcatcg attttgccgg cctcttcgcg agcaagctcg ctcccacatt
     4381 tggaatgcgc tcaccctgtg ggagcgagct tgctcgcgaa ggcgccaggc ctgacaacat
     4441 aaatctcaca gagtcaggtg aatctgccta ccccacactg gcccatctcc cccatgtcag
     4501 ctagcatcgc ccttttgcca ggactgccga ccatgaagat cgtttccttc aacatcaacg
     4561 gactgcgcgc ccgtccgcat cagttggcag cgctgatcga aaagcatcag ccggacgtga
     4621 tcggcctgca ggaaaccaag gtccacgacg accagttccc gctggaagaa gtgcgggcgc
     4681 tgggctatca cgtttatttc cacggccaga aaggccatta cggcgtcgcc ctgctctcgc
     4741 gcaacgagcc gatcgccgtt cacaaaggct tcgccaccga tgaagaagac gcccagcgcc
     4801 gcttcatctg gggcaccttc gccgacgcca atggcgtgcc ggtgaccatc atgaacggct
     4861 acttcccaca gggagaaagc cgcgaccatc cgaccaagtt cccggccaag caacgctttt
     4921 acagcgacct gcaaaccctg ctggaaagcc agttccacaa cgaacagccg ctggtagtga
     4981 tgggcgatgt gaacatttcc ccggaagacc gcgacatcgg catcggcccc gacaacatga
     5041 agcgctggct gaaaaccggt aaatgcagct tcctgccaga ggagcgcgag tggatggccc
     5101 gcctgaagaa ctggggcctg accgacagct tccgccacct gaacccggac gtgagcgaca
     5161 tgttcagctg gttcgactac cgcagccgtg gctttgaaga tgagccgaaa cgtgggctgc
     5221 ggatcgacgt gatcctcgcc tcccatggcc tgttgccgcg agtgaaggat gcgggcgtgg
     5281 actatgaact gcgcgggatg gaaaagccgt cggatcacgc gccgatctgg ctggaactgg
     5341 cctgatatcc accaagatca aaagatcgca gccttcggca gctcctacag gggatcgcat
     5401 tccaatgtag gagctgccga aggctgcgat cttttgatct gtcatgtttt ggtcatgcgt
     5461 ctgacttaat ctccccggca atccccttgg cttgattcgg tgccggcatg accctgcgtg
     5521 ttctgttcgt ctttgtgttg agtgcatggc tgacggtcag cgccgcaatc ctgccaatcc
     5581 ccgaaaacgg cccggcactg cgtattcagg gttccaatac cattggcgcc gatctcggcc
     5641 ccgcgctggt cgaaggtttt ttgcaggaac agggcctgct gaagatccac cgcgaaaacc
     5701 ccgacaccgc caacgaacaa cacattgttg gccagaccgc acaaggcaaa cgggtcgtga
     5761 ttgaagtcgc cgcccacggc tccagcactg gtttcaccgc actgaaaagc gccgctgccg
     5821 acctcgccgc cgcctcccgt ccgatcaagg acagcgaact gctcagcctg caagcgctgg
     5881 gcgacatgaa gagccctgag gccgagcaag tcatcgccat cgacggcctg gcgatcatcc
     5941 tgcatcccga caatccgctg cagcaactgg acaccgggca actggcgcgg atcttcgccg
     6001 gtgaggtgaa aacctgggaa gacctcggcg ggcgcggcgg tgcgatccat ctatatgcgc
     6061 gggatgatca gtccggcacc tacgacacgt tcaaggaact ggtgctgagt cgtcgcggga
     6121 aaagtctgag tgccacggcg aaacgcttcg agtccagcga gcaattgtcc gacgcggtga
     6181 gcagcgatgc gcaaggcatc ggtttcatcg gcctgcctta tgtgcgtcag gccaaagccg
     6241 tggcaatcgc cgacggtgca tcgcaatcga tgttgccgct caacagcctg atcgcgacgg
     6301 aagactatcc actgtcccga cggctgttct tttatctgcc acccaccagc cagaatccgt
     6361 gggcatcagc gctggtggcg tttgcgcaaa gcccacaggg gcagaagatt gtcgcggcca
     6421 acggtttcat cagccagacc atccatgcga tgaccgtcac gccgaatgcg ctgatgcccg
     6481 aggggtatca atccctcagc cggcatgccc aacgtctgac agtgaatttc cgctttgaag
     6541 aaggcagcgc cagcctcgac aacaaggcgc ggcaggatct ggcgcgggtg ctcgactata
     6601 taaagcgcca cgacaagacc gagcgtgcgg tgacgctggt gggctttggt gacgagaaag
     6661 acgacccggc ccgggccgac ctgctgtcga aactgcgggc catggcggtg cgccgcgagt
     6721 tggtgaagaa cggcgtggtg ttgcgcgagg tgcgcgggtt tggcgcgttg atgccggtgg
     6781 cggcgaacag tgcggatgag gggcggatca agaatcggcg ggttgaggtt tgggtgtatt
     6841 gagcctgatg ttgatggact gaatgggcag gccctttcgc gagcaagctc gctcccacag
     6901 ggatcgcatt cttccatttg gaatgcggtt taatgtggga gcttgctcgc gaagcaggcg
     6961 acgcggtctt aatgaccgct gcgcagcatc tctttcggca catacttgcc gatctcgaac
     7021 ttgccgatcg ccgcgcggtg cacttcgtcc gggccgtcgg ccaggcgcag ggtgcgttgc
     7081 atggcgtaca tgtaggccag cgggaaatcg ttcgacaccc cggccccgcc atggatctgg
     7141 atcgcccggt caatcacccg cagcgcgacg ttcggcgcga cgaccttgat ctgtgcgatc
     7201 tcgctcttcg ccactttgtt gcccacggtg tccatcatgt acgccgcctt cagagtcagc
     7261 aggcgcgcca tgtcgatttc catccgcgag tcggcgatct tgtcgacgtt accgcccaga
     7321 cgcgccagcg gtttgccgaa tgcggtgcgg ctcaccgagc gtttgcacat caattccagt
     7381 gcacgctcgg ccatgccgat cgaacgcatg cagtggtgaa tccgccccgg gccaaggcga
     7441 ccttgggcga tttcgaagcc gcggccttca ccgagcagga cgttttcgta cggcacccgc
     7501 acgttatcga acagcacttc ggcgtggccg tgcggtgcgt cgtcgtaacc gaacaccggc
     7561 agcggacgga cgattttcac cccgggggtg tcgaccggca ccaggatcat cgagtgctgg
     7621 gcgtggcgcg gtgcgtcggg gttgcttaga cccatgaaga tcaggatctt gcagcgcgga
     7681 tcgcaagcgc cggaggtcca ccattttttg ccgttgatca cccactcgtc gccgtcacgc
     7741 acggcgcggg cggccatgtt ggtcgcgtcg gacgaagcca cgtccggttc ggtcatggcg
     7801 aacgccgagc ggatttcgcc gcgcaacagt ggttcgagcc agcgctgttt ctgttcttcg
     7861 ttggcgtagc gcaccagcac ttccatgttg ccggtgtccg gcgccgagca gttgaacggc
     7921 tccggcccga gcaacgagcg acccatgatt tccgccagcg gtgcgtattc gaggttggtc
     7981 agcccggcgc cgagctccga ttccggcagg aacagattcc acaggccttc ggctttggcc
     8041 ttggctttga gttcttccat gatcgcggtc ggctgccagc gatcaccctc ggcaacctgg
     8101 cgttcgaaca cggcttcggc cgggtaaacg taagtgtcca tgaacgcggt cacgcgctca
     8161 cgcagttctt gcaccttggg cgaataagcg aaatccatga gcaattacct tctttaggca
     8221 gaggttgttc agatcatgca atcgatgcta gaacagcgct gataatttac ctagcctatt
     8281 ctcggcgtgt ataaacattc atcaccgata tatgatccgc tgatcgtcag gccttaaaac
     8341 atcagcccta aaacaagaga agccgcgtta tgaacctgag caaggtcgac ctcaaccttt
     8401 tcattgtctt cgacgcgatc tacaccgaag ccaacctgac ccgcgccggg cagattgtcg
     8461 gcatcaccca gccggcggtg tccaacgcgt tggcgcggtt gcgtgagacc ttcaacgatc
     8521 cgctgttcgt gcgcaccgcc cagggcatgg tgccgacgcc gatggcgcag aacatcatcg
     8581 gcccggtgcg caatgcgttg tcgctgctgc gggtgtcggt gcaggaaagc cggattttca
     8641 acccggccca ggcggtcaag acctaccgca tcagcatgac cgacctcact gaagcggtga
     8701 ttctgccgcc gctgttccag cgtttgcgac gtctggcgcc gacggtgatc atcgagagct
     8761 tcctgtccaa acgccgcgaa accaccaagg aactcgccgc cggacgcctg gatttcgccg
     8821 ttgatgcgcc gctcaacacc gacccgcagg tgcgccacgt caagctgatg gaagaccgtt
     8881 acgtctgcgc gatgcgcaag ggccatccgc tggcgggcaa ggaaaaactc agcctcgacg
     8941 attacctgtc gctgacccac attcatatct ccagccgccg cagcggcctg ggttatgtcg
     9001 atctggccct cggcaaaatg ggcattcagc gcaagatcgc cctgcgctca cagcattacc
     9061 tgatggcgtc tcaggtcatg cagcagaccg acatggtgat gacggtgccc gagcgctttg
     9121 cccggcgtaa cgacttgcat gcgttcaacc tgccggtcaa cgacgtgccg ccgctggaga
     9181 ctcatctgta ctggcacgaa agcaccgatc aggacccggc caaccgctgg atgcgcgagc
     9241 agatcatcga gttgtgccag caggtggcgg cgcaggagaa gaaactcgat aagcaggtgg
     9301 tttgaggaaa gatcaaaaga tcgcagcctt cggcagctcc tacaattgga atgcattttc
     9361 ctgtaggagc tgccgaaggc tgcgatcttt ttcttgcttg acgtaaacgt caactcgcca
     9421 ttagcttagc gccaagacct ttttcgagcg ctttcatgag cagccagacc tacagcattt
     9481 ccgacctcgc ccgcgagctg gacatcacca cccgggcgat ccgtttttat gaagaacaag
     9541 gcctgctcag ccctgagcgc cgtggccagg aacgcatcta ctcaccgcgc gacaaggtca
     9601 gcctgaagct gatcctgcgc ggcaagcgca tcggtttctc gctggccgaa tgccgcgagt
     9661 tgatcgaact ctacgacccg tccagcggta acaccaaaca gctcaacagc atgctggcga
     9721 aaatcagcga gcgccgcgaa cagctggagc aacagttgct cgacatcgaa cagatgaaac
     9781 tggaactcga taccgctgaa gaacgctgcg tgcaggcact ggagcagacg ctcaagagcc
     9841 agcagccggt tcagtaacca acacaaatcc ccttgtagga gtgagcctgc tcgcgatagc
     9901 ggtgggtcag tcaacatcac tgttgaatgt gaaatggcta tcgcgagcag gctcgctcct
     9961 caagggttct caacgatttc aaaagagcag gtcaaccgcc atgtccctcc cctcccatgt
    10021 tcgcctgatc gaagtcggcc cgcgcgatgg cctgcagaac gaagcccagc cgatcagcgt
    10081 ggctgacaag gtgcaactgg tcgacgcgct gagcgccgct ggtttgagtt acatcgaagt
    10141 cggcagtttc gtctcaccta aatgggtgcc gcagatggcc ggttcggccg aggtgttcgc
    10201 gcagatccag cgcaagcccg gcgtgaccta cggcgccctg gcgccgaacc tgcgcgggtt
    10261 tgaagatgcg ctggccgccg gcgtgaaaga agtcgccgtg ttcgccgccg cgtccgaggc
    10321 gttctcgcag cgcaacatca attgctcgat cagcgaaagc ctggcgcgct tcgcaccgat
    10381 catggaagcc gcgaaacagc acggcgttac cgtgcgcggt tacgtgtcct gcgtgctcgg
    10441 ctgcccgtac gaaggcacgg tcgccccgga gcaagtggcg atggtcgccc gtgagctgta
    10501 tgcgatgggc tgctatgaag tgtccctcgg tgacaccatc ggcaccggca ccgctggcgc
    10561 gacccggcgg ctgttcgaag tggtgtcggc gcaggtgcct cgggaaaaac tcgccgggca
    10621 cttccacgac acctacggcc aggccatggc caacatctat gccagcttgc tggaaggcat
    10681 cgcggtgttc gacagctcta tcgccggcct cggcggctgc ccgtacgcca agggcgcgag
    10741 cggtaacgtt gcgaccgagg acgtggtgta cctgctcaac ggcctgggca tcgagaccgg
    10801 tatcgacctg gacgccttga ttgccgcggg tcagcagatc agcgcggtgc tcggtcgccc
    10861 gagcggttcg cgtgtggcca aggcccgtaa cgcacagtga ggtcgaaggt gttaccgctg
    10921 tgtccgaaac gtgggcatag acgagtaaca cggaaacaaa ttgtctggtt tgccctgaag
    10981 gaaaaatcct tcaaaaaact caagccattg atttacaagg cttttaaaaa gttggcacgg
    11041 cttctgctat ctctatggca taacaagaat aaaaagctgc aaaccaataa aaataagacg
    11101 taccgactct gacataacaa aaacaacacg gcagagacgc agctaacaga tttttttgga
    11161 gaaggtgtgc ttttcagggt gctctcagga gtgacccgca accgggcaga gaacaataaa
    11221 actaccttca ggtagctccc gaatcggttg gatcgcttgg cgagaaagca gatcagcgct
    11281 caaaaaaata cgtttgctct tgaccccgga tgggggtcgc caaaaacagc ggtaaagggc
    11341 cacggttgcc aaaaacaaca acagaccgcc cctcaataat aagaaagagc acgcgacgac
    11401 aaaattaaag gggagcttcg gctccccttt gtgctttctg tgatttgtgt ttttaaaaga
    11461 tcgcagcctt cggcagctcc tacaccgatc ccctgtagga gctgccgaag gctgcgatct
    11521 tttgatcttc aatgtagcgc cttaagctct tcgatactga tctcgcgcat ccggaacttc
    11581 tgaatcttgc ccgtcaccgt catcggaaac tcttcgacga acttgaagta acgcggcgtc
    11641 ttgaagtgcg cgatgcgctc cttgcaccag gtttgcagtt ccagctcgga ggcattgtgg
    11701 ccggggtgga atttgatcca ggcgacaatc tcctcgccgt aacgcgagca cggaatgccg
    11761 atcacctgca cgtccgccac ggccgggtga gtgaagaaga actcttccag ctcacgcggg
    11821 taaacattct cgccgccgcg aatgatcatg tccttgttgc gcccggcgat gttcacgtaa
    11881 ccctcatcgt tcatgctcgc caggtcgccg gtgtgcatcc agcccgcctc atcgatggct
    11941 tcggcggtgg cctgcgggtt gttccagtaa ccgagcatca cgctgtaacc gcgggtgcac
    12001 aactcgccga tggtgccacg cggcaccaga tcgccggcct cgtcgatgat cttgctttcc
    12061 agttgcggct gagtgcggcc gacggtggtc acgcgcagtt ccagttcgtc gtttggcccg
    12121 gtctgtagcg acaccgggct ggtttcggtc atgccgtagg cgatctgtac ttcactcatg
    12181 tgcatctcgc tgatgacccg gcgcatcacc tcgatcgggc acgtggcgcc ggccatgatc
    12241 ccggtacgca ggctcgacag atcgaagtcc gcacgtagcg gttgatcgag catggcgatg
    12301 aacatggtcg gtacgccata gaggccggtg gcctgttctt cggcgacggt ttgcagggtc
    12361 agcagcgggt cgaaggcgtc gctggggtag atcatggtgc tggcgtgggt gatgcagccg
    12421 aggttgccca tgaccatgcc gaagcagtgg tacagcggca ccgggatcac cagccggtcg
    12481 ctcggggtca ggccgatgct ttcaccgacc atataaccgt tgttgagaat gttgtagtga
    12541 ctgagggtcg cgcccttggg gaaaccggtg gtgccggagg tgtattgaat gttcaccggt
    12601 tgatcgaaat gcaggctgtc gctgcgttcg tgcaactgtt ggggtgagac acccgcagcc
    12661 agatcggcca gttgcgacca cggcaggaag ccggacggtg gctgtgcatc gaggctgatt
    12721 accccgcgca actccggcag acgctcacag cgcaactggc cgatggattg ctcggccagt
    12781 tccggtacca gcccctgcag catggcgtgg tagttggagg acttgaatgc cccggcgcac
    12841 accagccact gacagccgga ctgtttgagc acgtattcca gttcagagct gcggtaggcc
    12901 gggttgatgt tgaccagaat cacgccgatt ttcgccgtgg cgatttgcgt gatgcaccac
    12961 tgcgcacagt tcggcgccca gataccgagc cgatcccccg cctgcaaacc cagcgccaac
    13021 agggctctgg catgcagatc caccgcgtcg gccagttgcc gccaggaata gcgcaactgc
    13081 tgatgacgca ccaccagcgc ctcaccgtcc gggtactgcg caactgtctg gtcgaacttc
    13141 tgcccgatgg tcatcgccag taaggctttg tcctgggcgc cacgggtgta gctgcgtggc
    13201 gggtttgcac tgggttgatc catgacgacc cctattgtct ttattgtagg agcgaggctt
    13261 ttgtggcgag ggagcttgct cccgctcggc tgcgcagcag tcgtgaaatc agcgatccgg
    13321 tgcagactga cacaccgcga acacccattt tgcgaccgct tcgcgctcga gctggagcaa
    13381 gctccctcgc cacagagagc gccgctggtc tttcagaact gcccttactc tcgctcaagt
    13441 tgacgttaac gtaaagggtg attgacagcc ttccgtctca ggcttacgtt aacgtaaagg
    13501 tgagagctgt tcgaccgccc tccccaccct acaaaaaagc taaaaggtgc cccatgagct
    13561 atccatcctt gaacttcgcc ctcggtgaaa ccatcgacat gctgcgcgat caggttcagt
    13621 cctttgtcgc cgatcagatc gccccacgcg ccgcgcagat cgaccacgac aacctgttcc
    13681 ctgccgacat gtggcgcaaa ttcggcgaca tgggcctgct cggcatcacc gtgccggaag
    13741 agtacggcgg cgccggcctg ggttacctgg cgcacgtggt ggcgatggaa gaaatcagcc
    13801 gcggttcggc ctcggtggcg ctgtcctacg gcgcgcattc caacctctgc gtcaatcaga
    13861 tcaaccgcaa tggcaaccac gagcagaaaa gccaatacct gccgaagctg atcagcggcg
    13921 aacacgtcgg cgccctcgcg atgagcgagc cgaacgccgg ttccgacgtg gtctcgatga
    13981 agctgcgcgc cgacaaacgc ggcgaccgtt tcgtgctcaa cggcagcaaa acctggatca
    14041 ccaacggccc cgacgccaac acctacgtga tctacgccaa gaccgatctg gaaaagggcc
    14101 cgcacggcat caccgccttc attgtcgagc gcgactggaa aggcttcagc cgcagcaaca
    14161 agttcgacaa gctcggcatg cgcggttcca acacctgcga gctgtttttc gatgacgtcg
    14221 aagtgccgga agaaaacatc ctcggcgtgc tcaacggcgg cgtcaaagtg ctgatgagcg
    14281 gcctcgatta cgaacgtgtc gtgctgtccg gcggcccgac cgggatcatg cagtcgtgca
    14341 tggacctgat cgtgccgtac atccacgacc gcaagcagtt cggccagagc atcggcgagt
    14401 tccagctgat ccagggcaaa gtcgccgaca tgtacaccca gctcaacgcc agccgcgcct
    14461 acctgtacgc ggtggcccag gcgtgcgagc gcggcgaaac cacgcgcaag gacgctgccg
    14521 gggtgatcct ctacaccgcc gaacgcgcca cacaaatggc cctcgacgcg atccagattc
    14581 tcggcggcaa cggttacatc aacgaattcc cggccgggcg tctgctgcgt gacgccaagc
    14641 tgtacgaaat cggcgctggc accagtgaga tccgacgcat gctgatcggc cgcgaactgt
    14701 tcaacgaaac gaaatgaatt tcgtcagcgg caagctgcga gcctcaagcg gcaagagaca
    14761 tgcgctcttg cctcaacttg cagcttgtag cttgaaactt caagctgcta cggagtagcc
    14821 catgatcctg catacccagc tcaatccccg ttcagcggag ttcgccgcca acagcgcggc
    14881 gatgctcgaa caagtcgacg ccctgcacac tctgctcgcc caagtggcgc agggtggcgg
    14941 cgcgaaagcc caggaacggc acacctcacg gggcaaactg ctaccgcgtg agcggatcaa
    15001 tcgtctgcta gaccccggct cgccctttct ggaaatcagc cagctcgctg cgcacgccgt
    15061 gtatggcgaa gacgtaccgg cggcgggcgt gatcgccggg atcggccggg tcgaaggcgt
    15121 cgagtgcatg atcgtcgcca acgacgcgac ggtgaagggc ggctcgtact acccgctgac
    15181 cgtgaaaaag cacctgcgcg cgcagaccat cgcccagcag aaccgcctgc cgtgcatcta
    15241 tctggtggac tcgggcggcg ccaacctgcc gcgtcaggac gaggtgttcc cggatcgcga
    15301 acacttcggc cggatctttt tcaaccaggc caacatgagc gccatgggca ttccgcagat
    15361 cgccgtggtc atgggttcct gcactgccgg tggtgcttat gtaccagcga tggccgacga
    15421 agcgatcatg gtgcgcaatc aggcgacgat cttcctcgcc ggcccgccgc tggtgaaagc
    15481 cgcaaccggt gaagtggtca gcgctgaaga cctcggcggt gccgatgtgc actgcaagat
    15541 ttccggcgtg gccgaccatt acgccgagag cgacgaacac gccctcgccc tcgcccgccg
    15601 cagcgttgcc aacctcaact ggcgcaagct cggcgaggtg caacaacgcg cgccgattgc
    15661 accgctgtac gccagcgatg agctgtatgg cgtggtctcg gccgacgcca agcagccgtt
    15721 cgacgtgcgc gaggtgattg cgcggctggt cgacggttcg gtgttcgatg agttcaaggc
    15781 gctgttcggc accacgctgg tgtgtggttt tgcgcacctg cacggctacc cgatcgcgat
    15841 cctcgccaac aacggcatcc tcttcgccga agccgcgcag aaaggcgcgc acttcatcga
    15901 actggcctgc cagcgcggta tcccgctgct gttcctgcag aacatcaccg gcttcatggt
    15961 cgggcagaaa tacgaggccg gcggcatcgc caagcacggt gcgaaactgg tgacggcggt
    16021 ggcctgcgcc aaggtgccga aattcaccgt gatcatcggc ggcagctttg gcgccggtaa
    16081 ctacggcatg tgcggacggg cttacgatcc gcgcttcctg tggatgtggc cgaatgcgcg
    16141 catcggtgtg atgggcgccg agcaggctgc cggcgtgctg gtgcaggtca agcgcgaaca
    16201 ggccgagcgc agcggccagg gcttcacggc cgagcaggaa accgagatca agcaaccgat
    16261 cctcgaccag tacgaagagc agggtcaccc ctactactcc agcgcacgcc tgtgggacga
    16321 cggcgtcatc gacccggcgc agacccgcga tgtgctggcc ctggccttgt ccgcgtcgtt
    16381 gaacgcgcct atcgaaccga gccgcttcgg cgtgttccgg atgtgatcgg gagaatctca
    16441 tgagcgactt caacaccctc gaactgcaga gcgacccacg gggtttcgcc acgctgtggc
    16501 tcaaccgtgc agaaaagaac aacgcgttca acgccgagat gatccgcgag ctgattctgg
    16561 cgctggacaa ggttgccagc gacgccagcc tgcgttttct gttggtgcgc ggacgtggca
    16621 aacacttcag cgccggcgcc gatctggcgt ggatgcagca atcggccgaa ctcgattacc
    16681 acaccaatct ggacgacgcc cgcgaactgg cggagctgat gtacaacctc gccaagctga
    16741 aaatcccgac cctggccgtg gtgcaaggtg cggcgttcgg cggcgcgctt gggctgatca
    16801 gttgctgcga catggcgatt ggcaccgatg atgcgcagtt ctgcttgtcg gaggtacgca
    16861 tcggcctggc gccagcggtg atcagtccgt tcgtggtgca ggccatcggc gaacgcgccg
    16921 cccgtcgtta cgcgctgacc gccgaacgtt tcggtggcca gcgggcgcgg gaaatcggct
    16981 tgttgtccga gagctatccg gccgtcgagc ttgatcaagc cgtcgagcaa tggatcgaca
    17041 acctgctgct caacagcccc gccgcgatgc gcgccagtaa agatctgctg cgcgaagtcg
    17101 gcaacggcgc gctgaccccg gccttgcgcc gctacaccga aaacgccatc gcgcgcatcc
    17161 gcgtcagccc tgaaggccag gaaggcttgc gcgcgttcct gcaaaaacgt gcgccgagct
    17221 ggcaagccgc aaccaccccc aaggagccgc gttgatgagc gcacctgttc tcaccaccct
    17281 gctggtggcc aaccgtggcg aaatcgcttg ccgggtcatg cgcaccgcca aggcgctggg
    17341 cctgaccacc gtcgccgtac acagcgccac cgaccgcgaa gcgcgccaca gccgcgaagc
    17401 cgacatccgc gtcgacctgg gtggcagcaa agccgccgac agctatctgc agatcgacaa
    17461 actgatcgcg gcggccaagg ccagcggcgc acaggcaatt cacccgggtt atggctttct
    17521 gtcggagaac gccggattcg ctcgcgccat tgaacaagcc gggttgatct tcctcggccc
    17581 acccgcttcg gccatcgacg ccatgggcag caagtctgcg gccaaggcct tgatggaaac
    17641 cgctggcgtg ccgctggtgc cgggctatca cggcgaggcg caggatctgg acaccttccg
    17701 cgatgcctgt gaacgcattg gctacccggt gctgctcaag gccacggcgg gtggcggcgg
    17761 caaaggcatg aaagtggtcg aggacgtcag ccaactggcc gaagccctgg cctcggccca
    17821 gcgcgaagcg cagtcgtcgt tcggcgattc gcggatgctg gtggagaaat acctgctcaa
    17881 gccgcgtcac gtggaaatcc aggtgttcgc cgaccagcac ggcaactgcc tgtacctgaa
    17941 cgaacgggat tgctcgatcc agcgtcgcca ccagaaagtc gtcgaagaag ccccggcgcc
    18001 aggcctgccc ccggaactgc gccgcgccat gggtgaagcg gcggtgcgtt cggcgcaggc
    18061 gatcggttac gtcggcgccg gcaccgtgga gtttctgctg gatgcgcgcg gcgaattctt
    18121 cttcatggaa atgaacaccc gtttgcaggt cgagcacccg gtcaccgaag caatcaccgg
    18181 cctcgatctg gtcgcgtggc agattcgtgt ggcgcgcggt gaagcgttgc ccatcacaca
    18241 ggatcaggtg ccgctcaacg ggcacgcgat cgaagttcgg ctgtatgccg aagacccgtc
    18301 gaatgacttc ctgcccgcga ccgggcgtct gcagctgtat cgtgaatcgg ctgccggtcc
    18361 ggggcgccgg gtggatagcg gggttgagga aggcgacgag atttcgccgt tctacgaccc
    18421 gatgctcggc aagctgattg cctggggcga ggaccgcgag caggcacgtc tgcgactgtt
    18481 gagcatgctc gatgagttcg ccattggcgg tttgaagacc aacatcaact tcctgcggcg
    18541 gatcattgcg catcccgcct ttgccgctgc ggaactggat accgggttta ttccgcgcta
    18601 tcaggaacaa ctgctgccgg ctccgggtga gctgggcgat gggttctggc atgcagcagc
    18661 gcaggctttc gcgcagagtt tgccgggcgc ggtgcgggcg gatgatttga gctcgccgtg
    18721 ggcgttgaac agtggtttgc gcgcaggttt gccggcggaa atcaccttgc atctgagctg
    18781 cgaaggccag gatcgcgcgt tgaccttgag tgccgccagc aacaccaggc tgtcgggcga
    18841 agcactgtgg gtcgagcacg acggcgtgcg tcgtaccttg cgcgccattc gccagggcga
    18901 ttcgttgtac ctgcaatggg acggcgagtt gcgccgcatc gagacctacg acccaatcaa
    18961 cgccgtcgaa gccagccaca gtcatcaggg cggtctgacg gcacccatga acggcagtat
    19021 cgtgcgggtg ttggtggagg ccgggcaatc ggtcgaggcc ggcgcgcaac tggtggtgct
    19081 ggaggcgatg aagatggaac acagcatccg tgcgccccat gcgggagtga tcaaagcgct
    19141 gtattgccag gaaggcgaaa tggttggcga aggcagcgct ttggttgaac tggaagccgt
    19201 gtaaatgagg agatcgatcc tacgcctgac gaggatcgat ctgactagaa acgcgccgtt
    19261 gcctgaacca cgacgccgat gattcgacac tcgtcggtga acagggcttt cggccaggtc
    19321 ggattgagcg gtaccaggta acgctggccg ccctcttcgt ccagtttgcg gaagatcgct
    19381 tcttcgctgt cctgccactg ggcgatcacc agtttgccgg gcaccgcttc cacctccgga
    19441 tccaccagga tcagcatgcc ttcggcaatg ctctgaccgg tgggtgcggt catcgaatcc
    19501 cccgtcaccg tcagccagaa cgccgcacca cgggcgtgat aatccgtcag ttcgaagcgc
    19561 tgcttgccat gcgccggggc ataggctgtg gttgcacttt cgcgaatttc acacgaggtg
    19621 cgccagtcgc tgaccgggta gcggaagtac gggttgtact tctgtgccag tggcatctcg
    19681 tcatccgccg cttcctgcgg ctcgcggatc accagtacca cttcgaggaa gtccatgccc
    19741 agcgcgtgca acacgcggtt catttgggtg atgcccggtt cgcgacgttt gttcagccaa
    19801 tggccgatgc cgccctggga catgccgacg cgctctccga gctctgtttg agtgattttg
    19861 agttcactca tcttggcctt gaccaactca atccatttat ccatgtgggg caccttacgt
    19921 cgacgccttc ggccggcaaa acacatattg tagtatttaa attctggtca caactacgca
    19981 tcgtactatc ctgaaagcac ggactttcaa tcgaacaagg agtgaccttt caccatgaat
    20041 atcagcagcg aagacttgcc cgatctgcaa atggacacca cgttcacctc ccctcaaggc
    20101 aacgcggcag cgcagcgggc gctggattat tacttgaaac cagctgtgtc agaacccgag
    20161 gtcgaagagc gttttttcga tgtgaaacgc catctcagcg gcgaagaagc cctggtgcat
    20221 gcctcggatc tgttgcgttg tgcagcggcc accgccttca aggcagcaga aaacctgcaa
    20281 ggcgcgagcc gcgacctggc cttttcggtg gtgcatatgg tggatatggc gcgggcgatg
    20341 gtcgaccatt cgatcgatgg cgaacagctc tgacgaacac ggcaaacgga cggacaggaa
    20401 agaattttcc catcgcgcag ataaaaacat ttgacttgca aatgataatg attattattg
    20461 caagcagctg gtcgcgagat cagtcgatgg accagagacc ttaggtcggt cttctggact
    20521 atctcctcat caggctaatc acggtttttg acccggcttt ttgccgggtc tttttttgcc
    20581 cgtttttcgg gcttatggct tcaggctaat gaagtctttg ggtgctgcaa attcgatggc
    20641 gcggataata tcaaaagaat atcgcttggc aagcgaagcc cggccacatt ggggcaaact
    20701 tacggcaatt agcacttgag aatcaatcgc acagtctcta agctgcttgc gcgtcatgga
    20761 ggacgccccc gccgcaaccc cgcaatttcc ctcggtttca cccctgtctt gcgtgtaaag
    20821 tagccgctat aaaaatcata ttcaggaacc gattatgacc gtggccaaat cttcgttcga
    20881 catcagcgcc aacttcgaca gcggcaacat tcaagtcatc gacctctcca atccgctcaa
    20941 cccggttctg gccattcgcc cggatacccg cagtgctcac tttcagtggt tccacttcaa
    21001 agccagcggc ctgcatgtgc atcaggagca ctggtttcgc ctggtcaacg ccagccaatc
    21061 ctcctataac aaggcctgga ccggctatca ggccgtcgct tcctacgacc acgtcaactg
    21121 gttccgcatt cctaccagtt tcgaaggcga cagcctgcgc ttttgcctcg aagccgagca
    21181 gacccacgcc tggttcgcct acttcgaacc ctatagccgc ggccgtcatg actggctgat
    21241 cgagcaggcg ctgaccaagg ccggcaccga gctgctggcc accggcaaga gcgtcgaggg
    21301 tcgagatatc caactgctgc gcaagggcag cggcgccgaa ggccggcgca aagtctggat
    21361 catcgctcag cagcacccgg gtgagcacat ggccgaatgg ttcatggaag gcgtgatcga
    21421 gcgcctggaa cgccacgaag acccggtgtt gaacaaactg ctggccagcg ccgatctgta
    21481 tctggtgccg aacatgaacc cggacggtgc cttccacggc cacctgcgca ccaacgccat
    21541 gggtcaggac ttgaaccgtg cctggcagaa cgccagtcag gaagtcagcc ctgaagtact
    21601 tttcgtacag cagcagatgg aaaagtacgg cgtcgatctg ttcctcgacg tacacggtga
    21661 cgaagaaatc ccccacgtgt tcactgccgg ttgcgaaggc aacccgggct acacgccgcg
    21721 tatcgagaag ctcgaagagc atttccgcac gcacctcaag cacaccacca aagacttcca
    21781 gacccagtac ggctacaccc gcgacgaacc gggccaggcc aacatgaccc tggcctgcaa
    21841 tgccgtcggc gagaaatatg actgtctgtc actgaccctg gaaatgccgt tcaaggacca
    21901 cgacgaccat cccgacaaag aaacgggctg gtccggcaag cgctccaaac agttgggcaa
    21961 ggacgtgctg accaccatcg ccgacatggt caacaccctg cgctgatccc tcccccgtca
    22021 cacccaaaga tcgcagcgtt gtctgcgatc tttttttttg cgcaatccac cgcctcgccc
    22081 gatcaggttg caaattaaaa ccagaatgct taccgtaact ctggttttaa tttgaaaccc
    22141 aaaaaggaat cagggcatgc aatctcaacc actcaaaagc agcgtggtgc tgctgttcgc
    22201 catcgcctgt ggtctggccg tgggcaacgt gtattacgcg cagccgctgc tggacgccat
    22261 agccgaggcg tttgccatgt cgccggcaac catcggcgtc gtcatcaccc tgacgcagat
    22321 cggctacggc atcggtctgg tgttgctggt gccactcggc gatctgctca accggcgccg
    22381 gctgatcgtc acccagaccc tgctctcggc agccgccctg ctgatgatcg cgctggcccc
    22441 cagcagtgtg tggttgctgc tcggcatgac cctgaccggg ttgctcgcgg tggtgacgca
    22501 agtgctggtg gcctacgccg cgacactggc tatcccggcg caacgcggtc gggtggtcgg
    22561 ggtcgtcacc agcggcatcg tcgtcggtat tttgctcgcg cgcaccattg ccggggccat
    22621 ggctgatctg gccggttggc gggcgatcta tctgctgtcg gcggggctga cgctgctgat
    22681 ggcgttgtta ctgttgcgtg tcctgcccaa ggatgaggcc gcgcagccgg ccagcagcta
    22741 tgtcgcgctg atcgcttcgg tgttcagcct gttcaggcaa gagccggtgc tgcgacaacg
    22801 ggcgatactc gccctgctga ccttcgccag cgccatggtc ctgtggacgc cgatggtgct
    22861 gccgctggcc gccccgcccc tgtcgttgtc acacagcgaa atcggcctgt tcggattggc
    22921 cggcgccgcc ggagcaatgg ctgcagcacg cgccggacat ctggcggatc gtggcctggg
    22981 ccaatgggtc agtggtctgt cgctgctgct gatgctcgcc tcgtggctgc cgatcgccct
    23041 cacccagtcg tcactctggg cactgttgct cggcgtgatc actctggatc tgggcttgca
    23101 ggccgtgcac gtcaccagtc agagcctgat ctacagcgtg cgccccgaag cgcaaagccg
    23161 tctcaccgcc ggctacatgc tgttttattc gatcggcagt gcagtgggct cgatcctttc
    23221 gac
//
