LOCUS       NZ_JAHHZH010000002     22157 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Pseudomonas sp. MG-9 NODE_2_length_790042_cov_67.6076, whole genome
            shotgun sequence.
ACCESSION   NZ_JAHHZH010000002
VERSION     NZ_JAHHZH010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas sp. MG-9
  ORGANISM  Pseudomonas sp. MG-9
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 790042)
  AUTHORS   Lutfullin,M.T., Pudova,D.S., Lutfullina,G.F., Vologin,S.G.,
            Gogoleva,N.E., Shagimardanova,E.I., Sharipova,M.R. and
            Mardanova,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2021) Microbiology, Kazan Federal University, 18
            Kremlyovskaya, Kazan, Tatarstan Republic 420008, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2021
            Assembly Method                   :: SPAdes v. v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018729515.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 03:27:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,693
            CDSs (total)                      :: 5,604
            Genes (coding)                    :: 5,536
            CDSs (with protein)               :: 5,536
            Genes (RNA)                       :: 89
            rRNAs                             :: 8, 9, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 6, 8 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 25 of 68
            Pseudo Genes (incomplete)         :: 48 of 68
            Pseudo Genes (internal stop)      :: 11 of 68
            Pseudo Genes (multiple problems)  :: 11 of 68
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:31:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 710292
            Orig. end                         :: 732449
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHHZH010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22157
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="2"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22157
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22157
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12157](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12157)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    complement(352..366)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    592..606
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(1528..1541)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    complement(1649..1664)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(1650..1663)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            1737..3026
                     /locus_tag="KKQ10_RS07915"
                     /old_locus_tag="KKQ10_07915"
     CDS             1737..3026
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007904190.1"
                     /locus_tag="KKQ10_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07915"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_215500724.1"
                     /transl_table=11
                     /translation="MPRSSAVRFSHFLPSLLLLLAGLAAAYVKDLNVFFTSLFNVLPTL
                     VLLLGGAYCAVYRRQRELFLMLTVYIAYFLLDTQTDYYRDNGKVREDAAVVFHLVCLLL
                     PLLFGLFAAWQERTHLFQDMVARFAVLLAFGSVALGLEQSYPQALLMWLSEIRWPALHG
                     AWMSLIQMSYPVFLSAFLLLAWQYWRSPRPLHAAQLVGLLGLFWMLPKTFILPFTLNIM
                     CSQVMLMIAAAVAHEAYQMAFRDELTGLPGRRALNERMQRLGRNYVLAMSDVDHFKKFN
                     DTHGHDVGDQVLRLVASKLSKISGGGRAYRYGGEEFALVFAGKTLEECMPHLEVIRESI
                     ASYNIQLRNQENRPQDDQQGRQRRGGSGASSVSVTVSIGVAERVEQRTPEEVLKSADQA
                     LYSAKGAGRNCVMAFGQSRRGAVRMDSVAG"
     misc_feature    complement(3073..3086)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    complement(3074..3087)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.93"
                     /tool="antismash"
     gene            3217..4995
                     /locus_tag="KKQ10_RS07920"
                     /old_locus_tag="KKQ10_07920"
     CDS             3217..4995
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249199.1"
                     /locus_tag="KKQ10_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07920"
                     /product="acyl-CoA dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_127647801.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.4e-13, bitscore:
                     46.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.6e-17, bitscore:
                     57.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.8e-23, bitscore:
                     76.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYKAPLRDMRFVLNEVFEVAKLWAELPALAETVDAETVEAILE
                     EAGKVTSKSIAPLSRAADEEGCHWKDGAVTTPAGFPQAYQTYAEGGWVGVGGDPAYGGM
                     GMPKAVSAQVEEMVNSASLSFGLYPMLTAGACLSINAHASEELKAAYLPNMYAGIWAGS
                     MCLTEPHAGTDLGIIRTKAEPQADGSYKVSGTKIFITGGEHDLTENIIHLVLAKLPDAP
                     AGPKGISLFLVPKFMVNADGSLGARNPANCGSIEHKMGIQASATCVMNFDEAVGYLVGE
                     PNKGLAAMFTMMNYERLGVGIQGLASGERSYQNAVEYARDRLQSRSPTGAQNKDKVADP
                     IIVHPDVRRMLLTMKASNEGGRAFSTYVAMQLDTAKFSEDATTRKRAEDLVALLTPVAK
                     AFLTDLGLETTVHGQQIFGGHGYIREWGQEQLVRDVRITQIYEGTNGIQALDLVGRKIV
                     GSGGAFYQLFADEIRHFTATASADLGEFTKPLNDAVGTLDELTAWLLDRAKTNPNEIGA
                     ASVEYLQAFGYTAYAYMWALMAKAALGKEAQDDFYASKLGTARFYFARLLPRIHSLSAS
                     VRAGSESLFLLNAEQF"
     gene            complement(5222..6151)
                     /locus_tag="KKQ10_RS07925"
                     /old_locus_tag="KKQ10_07925"
     CDS             complement(5222..6151)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008085162.1"
                     /locus_tag="KKQ10_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07925"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_215500725.1"
                     /transl_table=11
                     /translation="MDFKQLRYFVAVYEEGHVGRAAERLSISQPALSQQIRHLEQNLDV
                     TLFERSSKRLLPTLAAHTLYNHALPLLDGLQRAREALGNFKGQALRTLAIGVLQTVHTS
                     LVPQMLERVRKAQPHLVVQIYELSGLEIERRLLNGSLDIGISYLPPRQPGLHGVILYED
                     ELTLVIPADHPLREFKKVSISQAAELPMLLLGEEFQIRQIWQAQLTSLGRRPQVQAELN
                     NMLGILDSLPHTKLATVLPGRSKKEYDDQDLLWKPLSEPRVPLTVGLVCRDVQRQQASL
                     ALLRTLLEEVMQREEQPLKGAPTLDPLS"
     misc_feature    complement(6163..6177)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     misc_feature    complement(6199..6217)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.57"
                     /tool="antismash"
     misc_feature    complement(6292..6301)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     gene            6321..7604
                     /locus_tag="KKQ10_RS07930"
                     /old_locus_tag="KKQ10_07930"
     CDS             6321..7604
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (45-361). E-value: 1.3e-82.
                     Score: 269.4. Matches aSDomain:
                     nrpspksdomains_KKQ10_RS07930_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020796022.1"
                     /locus_tag="KKQ10_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07930"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_215500726.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.2e-88, bitscore:
                     291.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFSLLRQAPSLDDLAFEANPADAGASLNAERLMPSVERPQQVF
                     VRGQGSWLWDSNDRAYLDFAQAGGANSLGHSPSALVKAIAGQAQALINPGFNLHNRGML
                     SLAERLCASTSSDQAYLLNSGSEACEAAIKLARKWGQRHRGGASRIIVARHGCHGRSLA
                     TISASDSCNLHNRFAPLLPGFDRVPFNDLSALHAAIDAQTVAIMLEPIQSDAGVIPATE
                     HYLKGVERLCRELGILLILDEVQTGIGRCGTLLAEQSYGVRADIVVLGKGLGGGVPLAA
                     LLARGKACCFDAGELGGTHHGNALMTAAGLVVLDSVQDRAFLQQVNDHGQYLREGLARL
                     AHRYGHGELRGQGLFWGLTLSEDSADAVVNAALHEGLLLNAPQAGCLRFTPALTVSKAN
                     IDEMLLRLTRAFSRVRTAQLQCRKGIAV"
     aSDomain        6456..7403
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KKQ10_RS07930_Aminotran_3.1"
                     /evalue="1.30E-82"
                     /label="KKQ10_RS07930_Aminotran_3.1"
                     /locus_tag="KKQ10_RS07930"
                     /protein_end="361"
                     /protein_start="45"
                     /score="269.4"
                     /tool="antismash"
                     /translation="VRGQGSWLWDSNDRAYLDFAQAGGANSLGHSPSALVKAIAGQAQA
                     LINPGFNLHNRGMLSLAERLCASTSSDQAYLLNSGSEACEAAIKLARKWGQRHRGGASR
                     IIVARHGCHGRSLATISASDSCNLHNRFAPLLPGFDRVPFNDLSALHAAIDAQTVAIML
                     EPIQSDAGVIPATEHYLKGVERLCRELGILLILDEVQTGIGRCGTLLAEQSYGVRADIV
                     VLGKGLGGGVPLAALLARGKACCFDAGELGGTHHGNALMTAAGLVVLDSVQDRAFLQQV
                     NDHGQYLREGLARLAHRYGHGELRGQGLFWGLTLS"
     gene            <7766..7840
                     /locus_tag="KKQ10_RS28370"
                     /pseudo=""
     CDS             <7766..7840
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007980317.1"
                     /locus_tag="KKQ10_RS28370"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="NKHPSGMALKLLSIVQKHGLQILA"
     gene            7950..8108
                     /locus_tag="KKQ10_RS07935"
                     /old_locus_tag="KKQ10_07935"
     CDS             7950..8108
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249258.1"
                     /locus_tag="KKQ10_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07935"
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="WP_003228885.1"
                     /transl_table=11
                     /translation="MDFIRIIIAILLPPLGVFLQVGFGGAFWLNILLTLCGYIPGIVHA
                     VYIIAKR"
     gene            complement(8224..10035)
                     /locus_tag="KKQ10_RS07940"
                     /old_locus_tag="KKQ10_07940"
     CDS             complement(8224..10035)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007999152.1"
                     /locus_tag="KKQ10_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07940"
                     /product="S9 family peptidase"
                     /protein_id="WP_215500727.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.3e-49, bitscore:
                     164.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNETHASSPRAEPFSATQAVAAGMDFAELQLGANGLFWNEYRPED
                     AACRIWQWRDGVAKCLTPNGFSVRSRVYEYGGGAFCLTPDGVVFVNEADQQLYRQTLDG
                     APEALTSGECRYGDLHFAFGQVLAVEEQQDQHRLVAFDLADSTRHLLAEGADFYAAPIL
                     SPDGRRLAWIEWSRPHQPWTSTRLMVAERLTDGAFSSPRCVAGAECEESIKQPRFNAEN
                     RLYCLTDRAGFWQPWAETSDGLRPLPAAQADHAPAPWQLGGCTWCPVEDWFLASWSEGG
                     FGRLALGNEDFTGDYSRFRHLALDQQFIYCIAASPISPSAVIAIDRASHEVNVLAGGVA
                     PLPAERISRPQTLRYPSGSGEAHGFFYPAMNDEARPPLVVFIHGGPTSACYPMLDPRIQ
                     YWTQRGFAVADLNYRGSSGYGRAYRQALHLSWGEVDVEDACAVVAYLADQGLIDGERAF
                     IRGGSAGGYTTLCALAFQQVFRAGASLYGVSDPVALARATHKFEGDYLDWLIGDPEQNA
                     ERYAARTPLLHASNIRVPVIFFQGELDAVVVPQQTRDMVTALERKGIAVEAHYYADERH
                     GFRRAVNQAHALEQEWTFYRRVMGLAD"
     gene            complement(10001..11161)
                     /gene="pqqE"
                     /locus_tag="KKQ10_RS07945"
                     /old_locus_tag="KKQ10_07945"
     CDS             complement(10001..11161)
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009051182.1"
                     /locus_tag="KKQ10_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07945"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_064380312.1"
                     /sec_met_domain="PTHR43273 (E-value: 2e-30, bitscore:
                     101.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-25, bitscore: 86.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.1e-09, bitscore: 33.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.2e-06, bitscore: 22.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 33.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.9e-08, bitscore:
                     30.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSTGSPLTDLPPKPEVGLPLWLLAELTYRCPLQCPYCSNPLDFA
                     EQGKELSTEQWIKVFREAREMGAAQLGFSGGEPLVRQDLAELIREARQLGFYTNLITSG
                     IGLTEQKISDFKKAGLDHIQISFQASDEQVNNLLAGSKKAFAQKLEMARAVKAHGYPMV
                     LNFVTHRHNIDKIDRIIELCIALEADFVELATCQFYGWAQLNRVGLLPTKEQLVRAERI
                     TNEYRAKLEAEGHPCKLIFVTPDYYEERPKACMNGWGSLFLTVTPDGTALPCHGARQLP
                     VQFPNVRDHSMQHIWYDSFGFNRFRGYDWMPEPCRSCDEKEQDFGGCRCQAFMLTGDAS
                     NADPVCSKSEHHGVILKAREEAEHATQTIEQLAFRNERNSRLIAKG"
     gene            complement(11133..11408)
                     /gene="pqqD"
                     /locus_tag="KKQ10_RS07950"
                     /old_locus_tag="KKQ10_07950"
     CDS             complement(11133..11408)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011336229.1"
                     /locus_tag="KKQ10_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07950"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_025108597.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.5e-35, bitscore:
                     115.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-15, bitscore: 52.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNDSAALIG
                     GLIDGERDVAAIIAKLDEQFPGVPELGDDIEQFMEVARAQHWITLD"
     aSDomain        complement(11139..11405)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KKQ10_RS07950_PqqD_RRE.1"
                     /evalue="1.30E-36"
                     /identifier="RREFam006.1"
                     /label="KKQ10_RS07950"
                     /locus_tag="KKQ10_RS07950"
                     /protein_end="90"
                     /protein_start="1"
                     /score="115.2"
                     /tool="antismash"
                     /translation="SFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNDSAALIGG
                     LIDGERDVAAIIAKLDEQFPGVPELGDDIEQFMEVARAQHWITL"
     gene            complement(11405..12157)
                     /gene="pqqC"
                     /locus_tag="KKQ10_RS07955"
                     /old_locus_tag="KKQ10_07955"
     CDS             complement(11405..12157)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007926092.1"
                     /locus_tag="KKQ10_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07955"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_215500728.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.1e-127, bitscore:
                     419.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTPMSPTEFEAALRAKGAYYHIYHPYHVAMYEGRATREQIQGW
                     VANRFYYQVNIPLKDAAILANCPDREIRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVG
                     LDPDQLRSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPQH
                     YPWIDPAGYEYFRTRLGQARRDVEHGLAITLEHYRTREGQERMLEILQFKLDILWSMLD
                     AMSMAYELNRPPYHSVTEQRVWHKGITL"
     gene            complement(12298..13209)
                     /gene="pqqB"
                     /locus_tag="KKQ10_RS07960"
                     /old_locus_tag="KKQ10_07960"
     CDS             complement(12298..13209)
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701795.1"
                     /locus_tag="KKQ10_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07960"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_215500729.1"
                     /transl_table=11
                     /translation="MFVQILGSAAGGGFPQWNCNCVNCAGFRDGSLNAKARTQSSIAIS
                     DDGVNWVLCNASPDIRAQLQSFAPMQPGRALRDTGISAIILMDSQIDHTTGLLSLREGC
                     PHQVWCTDMVHEDLSTGFPLFKMLTHWNGGLNWNRIELDQSFTVAACPSLRFTPLPLRS
                     AAPPYSPHRFDPHPGDNIGLIVEDLNTGGKLFYAPGLGKVDAPLLEIMAGSDYLLVDGT
                     LWDDDEMQRRGVGTRTGREMGHLAQNGPGGMLEVLEQLPEQRKVLIHINNTNPILDEDS
                     AERAELARRNVEVAYDGMSIVL"
     misc_feature    13204..13215
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            complement(13291..13365)
                     /gene="pqqA"
                     /locus_tag="KKQ10_RS07965"
                     /old_locus_tag="KKQ10_07965"
     CDS             complement(13291..13365)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444522.1"
                     /locus_tag="KKQ10_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07965"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_003422658.1"
                     /transl_table=11
                     /translation="MSWTKPAYTDLRIGFEVTMYFASR"
     misc_feature    13514..13529
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            complement(13522..15939)
                     /gene="pqqF"
                     /locus_tag="KKQ10_RS07970"
                     /old_locus_tag="KKQ10_07970"
     CDS             complement(13522..15939)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007993184.1"
                     /locus_tag="KKQ10_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07970"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqF"
                     /protein_id="WP_215500730.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.8e-34, bitscore:
                     112.5, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.9e-10,
                     bitscore: 35.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPTHPRPHTETLANGLRVTLRHVPGLKRSAAALRVAAGSHDVP
                     LEWPGLAHFLEHLLFLGTKRFPADQALMAYVQGHGGQVNASTRERTTDFFFELPTSAFG
                     AGLERLSDMLAHPRMNPDDQLREREVLDAEFVAWSQDPTAQQALSLYEGLPAAHPLRGF
                     HAGNRDSLKVEQPTFQQALKDFHQRFYRSGQMTLSLVGPQNLEALRAMAQQFAAALPIG
                     NNVAQAATRPLQVKSYQQVGGQHRNLLFAFEALPDASIEALAFLCHWLNNAKPGGLLAH
                     LQQQNLADSLKATPLYHFAGQALLHLQFTAPTESMNVVGEQVLDWLSFFAAQQDWAALR
                     EEYAKLLERQQQVSGALQLARFDSEQLGHGLSENGVVALKQILRDIGVVDNFSAHWHLP
                     AANPFLGSSEPLANAGLIRGQTSAHRGLRTFAQDRSRSRRERSPMQFSQALADSGDEGA
                     IYLRWQLEAAATADLHGKLQRSLRETREDARQAGVELSFSASGTQWLLKLTGLQEPMPS
                     VLEHALKCLTQVDADSANAEPEAPLIPIRQLLKALPESCLPTAASSDDAKQLWTTSRWD
                     GLALGLSAQTQSGMGLALSRIPGIPDNLIPAPSASNTQKIWSHIDTASSEHALLLFCPT
                     ASREIADEAAWRLLAQLCQTPFYQHLRVELQLGYAVFSALRQMHGQTGLLFGVQSPSAA
                     PVALLGHIQQFLASVPGIIERLDDPSFNQQRQSLAEQFDESNLSAKDAAELLWQAKLAG
                     HSSDYLTQLLAAIAQLERPALLAAAQRLISTEGGWRCLASSASPGAPWQAGK"
     gene            complement(15988..16782)
                     /locus_tag="KKQ10_RS07975"
                     /old_locus_tag="KKQ10_07975"
     CDS             complement(15988..16782)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007947815.1"
                     /locus_tag="KKQ10_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07975"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_215500731.1"
                     /transl_table=11
                     /translation="MRVALYQCPPLPLDPAANLHRLHQVAMEAKGADLLVLPEMFLTGY
                     NIGAEAVSTLAEVYNGEWAQQIGRIAKAAGLAIVYGYPERTADGQIYNAVQLIDSHGER
                     LCNYRKTHLFGDLDRSMFSPGEDDFPLVELNGWKLGFLICYDLEFPENARRLALAGAEL
                     ILVPTANMIPFDFVADVTVRSRAFENQCYVAYANYCGQEGEIHYCGQSSIAAPDGSRIA
                     QAGLDEALIVGELDRQLMVDSRAANRYLSDRRPELYDALNKR"
     gene            complement(16795..18477)
                     /locus_tag="KKQ10_RS07980"
                     /old_locus_tag="KKQ10_07980"
     CDS             complement(16795..18477)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147187.1"
                     /locus_tag="KKQ10_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07980"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_215500732.1"
                     /transl_table=11
                     /translation="MNKNNRHPADGKKPVTIFGPDFPFAFDDWIEHPAGLGSIPEHHHG
                     AEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKLGGRLRSQTFNGTDGIVAELGGMRFP
                     VSSTAFYHYVDKLGLETKPFPNPLTPASGSTVIDLEGKTHYAQKLADLPALFQEVADAW
                     ADALEAGSQFSDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFHHR
                     EVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCV
                     HWPEGTSLKSLHRGAPRSGVKKIAHAPDGRFAVTDNNGDTREYAAVLTTCQSWLLTTQI
                     ECDETLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGT
                     YLFDNGDDKPGVICLSYSWMSDALKMLPHPVEKRVELALNALKKIYPKVDIAARIIGDP
                     ITVSWEADPYFLGAFKGALPGHYRYNQRMYAHFMQDDMPAEQRGIFIAGDDVSWTPAWV
                     EGAVQTSLNAVWGIMRHFGGSTHKENPGPGDVFKDIGPIALPE"
     gene            complement(18701..19162)
                     /locus_tag="KKQ10_RS07985"
                     /old_locus_tag="KKQ10_07985"
     CDS             complement(18701..19162)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020798842.1"
                     /locus_tag="KKQ10_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKQ10_07985"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_007910086.1"
                     /transl_table=11
                     /translation="MPDIRPPVLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSR
                     LARLEKAKVITGYGVRLGQRVVDGGLQAYVGIKVQPRSGKEVLRRLSAMAQVQQLCAVS
                     GEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGQPV"
     tRNA            complement(19296..19372)
                     /anticodon=(pos:complement(729628..729630),aa:Ile,seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="KKQ10_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="KKQ10_07990"
                     /product="tRNA-Ile"
     gene            complement(19296..19372)
                     /locus_tag="KKQ10_RS07990"
                     /old_locus_tag="KKQ10_07990"
     misc_feature    complement(19414..19431)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    20014..20028
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
     misc_feature    21288..21301
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    complement(21663..21677)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.75"
                     /tool="antismash"
     misc_feature    complement(21690..21704)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 aaggcggctg gccaagcctg gcgcacgatg tcgagcacgg cggtcaaggc ctgccggagt
       61 cgctgggtct ggcggtcagc gaaatggttg gcgaagccaa ctggtcgtgg ggcatgtacc
      121 caggcctgtc gcacggcgca atgaacacca tctccgagca cggcacccct gagcagcaag
      181 aagcctatct gaccaagctg gtttccggcg aatggaccgg caccatgtgc ctgaccgaac
      241 cgcactgcgg caccgacctg ggcatgctgc gtaccaaggc cgaacctcag gctgatggct
      301 cctacaaagt ttctggcacc aagatcttca tctcggccgg cgaacacgac atggccgaca
      361 acatcgtcca catcgtactg gcccgcctgc cggatgctcc ggctggcacc aaaggcattt
      421 ccttgttcat cgttccaaag ttcctgccga acgccgatgg caccatcggt gcgcgcaacg
      481 cagtgagctg cggttcgctg gaacacaaga tgggcatcca cggcaacgcc acttgcgtga
      541 tgaacttcga cggcgccacc ggttttctga tcggcccggc gaacaaaggc ctgaactgca
      601 tgttcacctt catgaacacc gcacgtctgg gtaccgccct gcagggtctg gcgcacgccg
      661 aaatcggctt ccagggtggc ctgaaatacg ctcgcgaccg tctgcaaatg cgctccctga
      721 ctggcccgaa ggcgccggac aaagccgctg acccgatcat cgtgcaccct gacgtacgcc
      781 gcatgctgtt gaccatgaag gcattcgccg aaggcaaccg tgcgatggtg tacttcaccg
      841 ccaaacaggt cgacatcgtc aaatacggcg tcgatgaaga agagaagaag aaagccgatg
      901 cactgctggc gttcatgacg ccgatcgcca aagcgttcat gaccgaagtc ggtttcgaat
      961 ccgccaacca cggcgtgcag atctacggcg gccacggctt catcgccgag tggggcatgg
     1021 agcagaacgt tcgcgacagc cgcatttcga tgctgtacga aggcaccacc ggcatccagg
     1081 ctcttgacct gctgggccgt aaagtgctga tgactcaagg cgaggctctg aaaggcttca
     1141 ccaaaatcgt ccacaagttc tgccagaaca acgaaggtaa cgaagccgtc aaagagttcg
     1201 ttgcaccgct ggctgcgttg aacaaagagt ggggcgagct gaccatgaag gtcggtatgg
     1261 cagccatgaa agatcgcgaa gaagtcggcg cggcctccgt ggactacctg atgtactccg
     1321 gttacgcctg cctggcctac ttctgggctg acatggcacg tctggccgcc gagaagctgg
     1381 ccgagggcac cggcgatgca gcgttctaca ccgccaagct gcaaaccgcg cgcttctact
     1441 tccagcgcat cctgccacgt acccgtaccc acgtggccac catgctgtcg ggcgccaaca
     1501 acctgatgga catgaaagaa gaagacttcg cgctgggtta ctaagcctta acgcggtctg
     1561 acgaaaccgc tgctccttcg ggggcagcgg ttttttttgt ttgtgaatcg ctcagaaacc
     1621 cggcttttct gccgttaaag agactgcatg tgatctggat cacattgtgt gtgcttaact
     1681 ggccacattg caggcacaat gccatctctt tgatatgacg ggtcggagtt ttacccttgc
     1741 cgcgttcttc cgctgtacgt ttcagtcatt tcctaccatc actgctgttg ttgcttgcgg
     1801 ggttggcggc tgcgtacgtc aaagacctca acgtgttctt cacttcgctg ttcaacgtgt
     1861 tgccgaccct ggtgctgctg ttgggcggtg cttactgtgc ggtttaccga cgtcagcgcg
     1921 aactgtttct gatgctcacg gtgtacatcg cctacttttt gctcgacacc cagaccgact
     1981 attaccgcga caacggcaaa gtgcgcgaag acgctgctgt ggtgttccat ctggtctgcc
     2041 tgctgctgcc gttgttgttc ggcttgtttg ccgcgtggca ggagcgtacc catctgtttc
     2101 aggacatggt cgcgcggttc gccgtactgc tcgctttcgg cagcgtcgcc ctcggtcttg
     2161 agcaaagtta tcctcaagcg ctgttgatgt ggctctcgga gatccgctgg ccagcgctgc
     2221 acggtgcctg gatgagcctg atccagatgt cttacccggt gttcctctcg gccttcctgt
     2281 tgctggcctg gcaatactgg cgcagcccgc gaccgctgca tgcggcgcaa ctggtcggcc
     2341 tgctcggctt attctggatg ctgccgaaaa ccttcatttt gccgttcacc ctgaacatca
     2401 tgtgcagcca agtgatgctg atgattgctg cggcagtagc gcacgaggcc taccaaatgg
     2461 ccttccgtga tgagctcaca gggctgccgg ggcgtcgcgc gctcaatgag cgcatgcagc
     2521 gcctgggccg caactatgtg ctggcgatga gcgacgtcga tcacttcaag aaattcaacg
     2581 acacccacgg tcacgacgtg ggtgaccagg tgctgcgact ggtcgccagc aaactgtcga
     2641 aaatcagcgg tggcggtagg gcgtatcgct atggtggtga ggaattcgct ctggtgtttg
     2701 caggcaaaac ccttgaggag tgcatgccgc acctggaagt cattcgtgag tcgattgcct
     2761 cttacaacat ccagttgcgc aatcaggaga accgtccgca ggacgaccag caaggtcgcc
     2821 agcgccgagg cggctccggt gcctccagtg tgtcggtcac ggtcagtatc ggcgttgccg
     2881 agcgcgtgga gcagcgcacc ccggaagaag tcctgaagtc tgccgaccag gcgttgtaca
     2941 gcgccaaagg ggcgggtcgt aactgcgtca tggcgttcgg gcagagccgg cgcggggcgg
     3001 tgcgcatgga tagcgtcgcc ggctgaatcg agtcccgccc gttttgataa agagcccgct
     3061 gatgcgggct tctttttgtt caaaaatgct gatgactaaa aataacaaat cagtcactgc
     3121 ctgaccctat gtgtcgcaaa agttgttggg gtacactcgg cctcaaagaa aaccatcctt
     3181 ccacgaatta cctgtttaga tcttgcgagg tttgccatgg ctgactacaa agcgccgctg
     3241 cgcgatatgc gcttcgtcct caatgaagta ttcgaggtcg ccaaactctg ggccgaactg
     3301 ccggccttgg ccgagaccgt cgacgccgaa accgtagaag ccattctcga agaggccggc
     3361 aaggtcacca gcaaaagcat cgcaccgctg agccgggctg ccgacgaaga aggctgccac
     3421 tggaaggacg gtgctgtcac cacgccggcc ggtttcccac aggcttatca gacttacgct
     3481 gaaggcggct gggtcggtgt cggtggcgat ccggcttatg gcggcatggg catgcccaaa
     3541 gccgtttcgg ctcaggtcga agagatggtc aactccgcca gcctgtcgtt cggtctgtat
     3601 ccgatgctga ctgccggcgc ttgcctgtcg atcaatgccc acgccagcga agagctgaaa
     3661 gcggcgtacc tgccgaacat gtacgccggc atctgggccg gttccatgtg cctgaccgag
     3721 ccgcacgccg gcaccgacct gggcatcatc cgtaccaagg ccgagcctca ggccgacggc
     3781 tcctacaagg tcagcgggac caagatcttc atcaccggcg gtgaacacga cctgaccgaa
     3841 aacatcattc acctggtgct ggcgaaactg ccggacgccc cggctggccc gaaaggcatt
     3901 tcgctgttcc tggtgccaaa gttcatggtc aatgccgatg gcagcctggg cgcgcgcaac
     3961 ccggcgaact gcggttcgat cgagcacaag atgggcattc aggcgtccgc gacctgcgtg
     4021 atgaacttcg acgaagccgt gggttatctg gtcggcgagc cgaacaaggg cctggcggcg
     4081 atgttcacca tgatgaacta cgagcgtctg ggtgtcggca ttcaaggcct ggccagtggc
     4141 gagcgttcct accagaacgc tgtcgaatac gcccgcgatc gtctgcagag ccgttcgccg
     4201 accggcgcgc aaaacaagga caaagtcgca gacccgatca tcgtccaccc ggacgtgcgt
     4261 cgcatgctgc tgaccatgaa agcctccaac gaaggtggcc gcgcattctc cacctacgtg
     4321 gcgatgcagc tcgacaccgc caagttcagc gaagacgcca ccacccgcaa gcgtgcggaa
     4381 gacctggtgg cgctgttgac gccagtggcc aaggcatttc taaccgacct ggggctggaa
     4441 accaccgtcc acggccagca gatcttcggc ggccacggct acatccgcga gtggggccag
     4501 gagcaactgg tgcgtgacgt gcgcatcacc cagatctacg aaggcaccaa cggcattcag
     4561 gcactggacc tggtcgggcg caagatcgtt ggcagcggtg gcgcgttcta ccagctgttc
     4621 gctgacgaga tccgtcactt caccgcgact gccagcgctg acctgggcga gttcaccaag
     4681 ccactgaacg atgccgttgg caccctcgac gagctgactg cctggctgct ggatcgggcg
     4741 aaaaccaatc cgaacgaaat cggcgcggct tcggtcgagt atttgcaagc gtttggttac
     4801 accgcctacg cctacatgtg ggcattgatg gcgaaagccg cgctgggcaa agaagcgcag
     4861 gacgatttct acgccagcaa gctgggcacc gcgcgtttct atttcgcccg tctgttgccg
     4921 cgcatccact cgctgagcgc gtcggtgagg gctggcagtg agtcgctgtt cctgctgaac
     4981 gccgaacagt tctgatgaag taacgtcatg taagcattct cttacatgac gtgctgctgt
     5041 tctcccatag gcgtagattg gatccacagc taatctacaa ctcatggacg tcgcgcagga
     5101 agcgcaaagc aacaacacgg acacgtagga ttctgccagg gtggcggagt gaaatggatg
     5161 tcagggaaac agtctgcaaa gccccgcttc ggcggggttt tcttttgcct gaagaaaagt
     5221 ttcagctcaa gggatccagc gtcggcgcac ctttgagcgg ttgttcctca cgctgcatca
     5281 cctcttccag caaggtgcgc agcaacgcca aggacgcctg ctggcgctgc acgtcgcggc
     5341 acaccaggcc gactgtcagc ggcacccgcg gttcgctcag cggtttccac aacagatcct
     5401 gatcgtcgta ttccttcttt gatcgcccgg gcagcaccgt cgccagcttg gtgtgcggca
     5461 ggctgtcgag aatccccagc atattgttca gttcggcctg cacttgcggg cgtcgtccca
     5521 ggcttgtcag ctgagcctgc cagatctggc gaatctgaaa ttcttcgccc agcagtaaca
     5581 tcggcagctc ggccgcctga ctgatggaga ccttcttgaa ttcccgcaac ggatgatccg
     5641 ccgggatcac cagcgtcaac tcatcttcgt acagtatcac gccatgcagc ccgggctgtc
     5701 gcggtggcag gtagctgatg ccgatgtcga gcgaaccatt gagcagacgg cgctcgatct
     5761 ccagtccgct gagctcatag atctgcacca ccaggtgtgg ctgtgccttg cgcacccgct
     5821 ccagcatttg cggcacgaga ctggtgtgta cggtttgcag cacgccaatc gccagggtac
     5881 gcaacgcctg gcccttgaag ttgcccagcg cctcacgcgc ccgttgcaga ccatcgagca
     5941 gcggcagggc gtggttgtac aaggtgtgag cggcgagggt cggcagcagg cgtttgctgc
     6001 tgcgttcgaa cagggtgacg tcgaggttct gttcaagatg gcgaatctgt tgcgacagcg
     6061 ccggttgcga gatcgacagg cgctcggcag cccggccgac atgcccttct tcgtagaccg
     6121 cgacgaaata acgcagttgt ttgaaatcca taagtaattc ttatcgaaaa tgctgataaa
     6181 tcgaaatggc ccgaagtcct cggtgagcct agtctaaccg caatcacaag gcttacaggg
     6241 ccagaaagcg cgatgaatag cgtttgcttc gacagtgttt gcataggcag ttcaaaaaac
     6301 ctcagacgag gtttttgtca atgaatctgt tcagtttgct gcgccaggcg ccgagtcttg
     6361 atgacctcgc gttcgaggcc aacccagccg atgcaggcgc aagcctgaat gccgagcggc
     6421 tgatgcccag cgtcgaacgc ccgcaacagg tgttcgttcg cggccagggc tcctggctgt
     6481 gggacagtaa cgatcgcgct tatctcgact tcgcccaggc cggcggcgcc aacagcctcg
     6541 gtcacagccc ttcggcgctg gtcaaagcga ttgccggtca ggctcaggcg ctgatcaatc
     6601 ccggtttcaa tctgcacaat cgcggcatgc tcagcctcgc cgagcgactg tgtgccagca
     6661 cctcaagcga tcaggcctat ttgctcaaca gcggcagcga agcctgtgaa gcggcgatca
     6721 aactggcgcg taaatggggc cagcggcatc gtggcggcgc gtcgcggatc atcgttgcca
     6781 gacacggctg ccacggccgt agtctggcga cgatttcggc gtcggacagt tgcaacctgc
     6841 acaaccgttt cgcaccgttg ttgccgggtt tcgatcgggt gccgttcaat gacttgtcgg
     6901 cgctgcatgc ggctattgat gcgcaaaccg tggcgatcat gctcgaaccg atccagagtg
     6961 atgccggggt gattccggcc accgaacatt acctcaaagg cgtcgagcgg ctgtgccgcg
     7021 agctgggcat tctgctgatc ctcgatgagg ttcagaccgg catcggtcgc tgtggcactt
     7081 tgctcgccga acagtcctac ggcgtacgcg ccgatatcgt cgtgctcggc aagggccttg
     7141 gtggcggcgt gccgctggcg gcattgctgg cccggggcaa ggcctgctgc ttcgatgcgg
     7201 gtgaactggg cggcactcat cacggcaacg cactgatgac cgcggccggt ctggtggtgc
     7261 tcgacagcgt gcaggaccgg gcgtttctgc agcaagtcaa cgaccacggc cagtacctgc
     7321 gcgagggcct cgcgagactg gcgcaccgtt acggtcatgg cgagttgcgc gggcaagggc
     7381 tgttctgggg gctgacgctg tcagaggatt ctgccgatgc cgtggtcaat gccgccttgc
     7441 atgagggctt gttgctcaac gcaccgcaag ccggctgcct gcgtttcacc ccggcactca
     7501 ctgtcagcaa ggccaacatc gacgaaatgc tcctgcgcct gacccgagcc ttctcgcggg
     7561 tacgcaccgc gcaactgcaa tgccgcaaag ggattgccgt ctgagctgaa ctttcctacc
     7621 cgatttcaag aaccgtctcg cggtataacg cacgcctcac gcctgattct tttggcgtga
     7681 ggcgtttttt tgtgcccgag ttttaccgag tgccttttgg cgcttgaggt attgccgggc
     7741 gggtggtctt ttagaaagcg ccgacaacaa gcaccccagt ggaatggcgc tgaaactgct
     7801 gagtattgtg cagaaacacg ggctgcaaat tctcgcttga gccatcaatt tgataccgac
     7861 ctggtgattg gcactgaacc ctgacgaacc gcacgggtcg attagcgtgt atggctcaag
     7921 tgagccaacc cccaatcagg agctgatcca tggatttcat tcgtatcatc atcgccattc
     7981 tgttgccgcc actgggtgtg tttcttcagg tcgggtttgg cggggcgttc tggctgaaca
     8041 ttctgctcac gctgtgtggc tacattcctg ggatcgtgca tgcggtgtac atcatcgcca
     8101 agcgctgagt gctgcgacgc cagctagata gccttcgcga gcaagctcgc ccacatttga
     8161 tcgtgctatc aacacaaaaa actgtggggg cgagcttgct cgcgaagggg gcgactcggt
     8221 ttttcagtcc gccaatccca ttacccgccg ataaaacgtc cactcctgct ccagcgcatg
     8281 cgcctgattc accgcccggc gaaagccatg gcgctcgtca gcgtagtaat gcgcctcgac
     8341 cgctatgccc ttgcgctcca gcgcggtgac catgtcgcgg gtctgttgcg gcacgacgac
     8401 ggcgtccagt tcgccctgaa agaaaattac cggcacacga atgttgctcg cgtgcagcaa
     8461 gggcgtgcgg gcggcgtagc gctcggcgtt ctgctcggga tcgccgatca gccagtcgag
     8521 gtaatcgccc tcgaacttgt gcgtcgcccg ggccagtgcc accgggtcgc tgacgccgta
     8581 caaactggca cccgcgcgga acacctgttg aaacgccaac gcgcataacg tggtgtaacc
     8641 cccggcgctg ccgccgcgga tgaaggcgcg ctcgccgtcg atcaggcctt ggtcggccag
     8701 gtacgccacc accgcgcagg cgtcctcgac atccacctcg ccccagctca ggtgcaacgc
     8761 ctggcgatac gcgcggccat aaccgctgct gccccggtag ttgagatcgg cgacggcgaa
     8821 accgcgttgc gtccagtact ggatgcgcgg gtcgagcatc gggtagcagg ccgacgtcgg
     8881 gccaccatga atgaacacca ccagcggtgg tctggcttcg tcattcattg ccgggtagaa
     8941 gaaaccgtgg gcttcacccg agccgctcgg ataacgcagg gtttgcggac ggctgatgcg
     9001 ttcggcgggc agtggcgcca cgccaccggc cagcacgttg acttcatgac tggcgcgatc
     9061 aatggcgatt accgccgaag ggctgatcgg cgaggcggcg atgcagtaga tgaattgctg
     9121 atccagcgcc agatgccgga agcggctgta gtcgccagtg aagtcttcgt tgccgagcgc
     9181 caggcggcca aaaccgcctt cgctccagct cgccaaaaac caatcctcga cagggcacca
     9241 ggtgcagccg cccagttgcc acggcgccgg cgcatgatct gcctgggccg ctggcaatgg
     9301 ccgcaagccg tcggaggttt cagcccaagg ctgccagaac ccagcgcgat cggtcaggca
     9361 gtacaggcga ttttctgcat tgaatcgcgg ttgcttgatg gactcttcac actcggcgcc
     9421 agccacgcat cgcggggagc tgaatgcacc gtcggtcagg cgttcagcca ccatcaaccg
     9481 cgttgaggtc cacggttgat gcggccggct ccactcgatc cacgccaaac gtcggccatc
     9541 cgggctgagg attggcgcgg cataaaaatc cgcaccttca gccagcaaat gccgggtgct
     9601 gtcagccaga tcaaacgcta caagccgatg ttgatcttgc tgctcctcaa ccgccagcac
     9661 ctggccgaaa gcaaaatgca gatcgccata acgacactcg cctgacgtca gcgcctcagg
     9721 cgcgccatcc agcgtctgcc gatacagctg ctggtctgcc tcattgacga aaaccacgcc
     9781 gtccggcgtc agacaaaacg caccaccgcc atattcgtac acccgactgc ggacactgaa
     9841 gccattgggc gtcagacatt tcgccacgcc gtcgcgccac tgccagatcc ggcacgcggc
     9901 atcttccggg cgatattcat tccagaacaa accgttggca ccgagctgca gctcggcgaa
     9961 atccataccg gcggcgacgg cctgggtggc gctgaaaggc tcagcccttg gcgatgaggc
    10021 gtgagtttcg ttcattacgg aaggccagtt gttcgatggt ctgggtggcg tgctcggctt
    10081 cttcgcgggc cttgaggatc acgccgtgat gttcggattt gctgcacacc gggtcggcgt
    10141 tgcttgcgtc acccgtgagc atgaacgcct gacagcggca gccgccgaaa tcctgttcct
    10201 tttcgtcgca ggagcggcac ggctcgggca tccagtcgta accgcgaaaa cggttgaagc
    10261 cgaacgagtc gtaccagatg tgctgcatgc tgtgatcgcg cacgttggga aattgtaccg
    10321 gcagctgtcg ggcaccatgg cagggcaggg cggtgccgtc cggcgtcact gtcagaaaca
    10381 ggctgcccca gccgttcatg caggctttcg ggcgttcttc gtagtagtcc ggggtcacga
    10441 atatcagctt gcacggatgc ccttcggcct ccagtttggc gcggtattcg ttagtgatgc
    10501 gctcggcgcg caccagttgt tccttggtcg gcaacaggcc gacgcggttg agctgcgccc
    10561 agccatagaa ctggcaagtg gcaagttcga cgaagtcggc ctccagcgcg atgcacagct
    10621 cgatgatgcg gtcgatcttg tcgatgttgt gccgatgggt gacgaagttc agcaccatcg
    10681 gataaccgtg agccttcacc gcccgggcca tttccagctt ctgcgcgaag gcctttttcg
    10741 agccggcgag caggttgttc acttgctcgt cgctggcctg gaaactgatc tggatgtgat
    10801 cgaggccagc cttcttgaag tcgctgatct tctgctcggt caggccgatg ccggaggtga
    10861 tcaggttggt gtagaaaccc agctgccgcg cttcacgaat cagttcggca aggtcctggc
    10921 gcaccaatgg ctcgccaccg gaaaagccca gttgcgcggc gcccatctcc cgcgcctcgc
    10981 gaaatacctt gatccactgc tcggtgctca gctctttgcc ttgctcggcg aaatccagcg
    11041 gattggagca gtacgggcat tgcagcgggc agcggtaggt cagttcggcg agcagccaca
    11101 gcggcagacc gacttcaggc ttgggcggca gatcagtcaa gggtgatcca gtgctgcgca
    11161 cgggcaacct ccatgaattg ctcgatgtcg tcaccgagtt caggcacgcc ggggaactgc
    11221 tcatcgagtt tggcaatgat cgctgcgaca tcgcgttcac cgtcgatcaa accaccgatc
    11281 agcgcggcgc tgtcgttgag tttgatcatg ccttcggggt agagcagcac gtggcctttt
    11341 tgcgccggtt cgtactggaa acggtatccg ggacgccagg tcggggtctt gctgcgatcg
    11401 aaactcatag ggtgattcct ttgtgccaga cccgttgctc ggtgacgctg tgatacggcg
    11461 ggcggttcag ttcgtaagcc atgctcatgg catcgagcat gctccaaaga atgtccagtt
    11521 tgaactggag aatttccagc atgcgctcct gaccctcacg ggtcctgtag tgctcgagcg
    11581 tgatcgccag accatgctcg acatcccgcc gcgcctggcc gaggcgggtg cggaaatatt
    11641 cgtagccggc cgggtcgatc cacgggtaat gctgcggcca gctgtcgagg cgtgactggt
    11701 ggatctgcgg cgcgaacagt tcggtcagcg aactgctggc ggcttcctgc caactggcac
    11761 ggcgggcgaa gttgacgtag gcgtcgacag cgaaacgcac gccgggcagc accagttcct
    11821 gagagcgcag ttgatccggg tcgaggccga ccgcttgacc gaggcgcagc caggcttcga
    11881 taccgccgtc ttcaccgggg gcgccgtcgt gatcgagcag gcgttgaatc cactcgcggc
    11941 gaatctcgcg atccgggcaa ttggcgagga tggccgcgtc tttcaggggg atgttcacct
    12001 gataatagaa gcggttggcg acccagccct gaatctgttc gcgggtggcg cggccttcat
    12061 acatcgccac gtgatacggg tggtagatgt ggtagtaggc gcccttggcg cgcagagccg
    12121 cttcgaattc ggtgggggac attggcgtgt cagtcatgtc tgttctccgg ggaacaaccc
    12181 tagaaatatc tggtgtctgt gccggcctta tcgcgagcag gctcactcct acaggtgatc
    12241 gcattccaat gtaggagtga gcctgctcgc gatagaccgc gcagcggtct caaatgctta
    12301 caacacaata ctcatgccgt catacgccac ttcaacattg cgccgcgcca gctccgcacg
    12361 ctcagccgaa tcctcatcga gaatcgggtt ggtgttgttg atgtggataa gcaccttgcg
    12421 ctgctcaggc aactgctcca gcacttcgag catgccgccg gggccgttct gcgccaggtg
    12481 gcccatctcg cgaccagtgc gggtgccgac gccacggcgc tgcatttcat cgtcgtccca
    12541 cagcgtgccg tccaccaaca ggtaatcgct gccggccatg atctccagca ggggcgcgtc
    12601 gaccttgccc aggcccgggg cgtagaacag tttgccgccg gtgttgaggt cttcgacgat
    12661 caggccgatg ttgtcgcccg ggtgcgggtc gaagcgatgc ggcgagtagg gcggtgcggc
    12721 gctgcgcaac ggcagcgggg tgaaacgcag gctcgggcag gctgccacgg tgaagctctg
    12781 gtcgagttcg atgcggttcc agttcaagcc gccgttccag tgggtgagca tcttgaacag
    12841 cgggaaaccg gtgctcaggt cttcgtgaac catgtccgta caccagacct gatgcgggca
    12901 gccttcgcgc aggctgagca ggccggtggt gtggtcgatc tggctgtcca tcaggatgat
    12961 cgcgctgatg ccggtgtcac gcagggcgcg gcccggttgc atcggggcga agctctgcag
    13021 ttgcgcgcgg atgtccggcg aagcgttgca cagcacccag ttcacgccgt catcggaaat
    13081 tgcgatggac gattgggtgc gggccttggc attcaggctg ccgtcgcgaa agcctgcgca
    13141 attgacgcag ttgcagttcc actgcggaaa accgccaccg gcggccgaac ccagaatctg
    13201 gacgaacatg aacgctccca tctttcaacg ctgaaaataa aacgccccgg cgagccgagg
    13261 cgttgcactg caagtctgcg taggcagaac tcagcggctg gcgaagtaca tggtgacttc
    13321 aaagccgata cgcaggtcgg tgtaagccgg ttttgtccag gacatgggtg tctccttcag
    13381 ggtgggtggg atagcgctgt ccatagttat agtccacggc agcgcaggga tgttccaaat
    13441 agttaggcgg ctatgttact caaaatttcc aggtgaatgc ccgtgaatct ttgagaaagc
    13501 tccttgcagc ctgagtaatg atcattttcc tgcttgccac ggcgcacccg gtgacgcgct
    13561 gctggccaga cagcgccagc cgccctcggt gctgatcaag cgttgagctg ccgccagcag
    13621 tgccgggcgc tccagttgcg cgatggccgc gagcagttgc gtcagataat ccgacgagtg
    13681 accggcgagc ttggcctgcc acagcaactc ggcggcgtcc ttggcggaca gattgctctc
    13741 gtcgaattgc tccgcgagtg actggcgctg ctggttgaag ctggggtcat ccaggcgttc
    13801 gataatcccg ggaacgctgg cgaggaactg ctggatatgc ccgagcaacg ccactggagc
    13861 agcgctgggt gactgcacgc caaacagcaa tccggtctgg ccgtgcatct ggcgcaaggc
    13921 gctgaacacc gcgtaaccca attgcaattc gacccgcagg tgctgataga acggtgtctg
    13981 gcacaactgt gcgagcagac gccaggcggc ttcgtcggcg atctcgcggc tcgcggtcgg
    14041 gcagaacagc agcagcgcat gttcgctgga ggccgtgtcg atgtggctcc atatcttttg
    14101 agtgttgctc gctgacggtg cggggatcag gttgtccggg atgccgggga tgcgactcag
    14161 ggccaggccc atgccggatt gggtttgcgc gctgaggcca agggccagtc cgtcccagcg
    14221 ggaagttgtc cacagctgtt tggcgtcgtc cgaacttgcc gccgttggca ggcagctttc
    14281 cggcaatgcc ttgagcaact ggcggatcgg gatcagcggc gcttctggct ccgcgttcgc
    14341 agaatcggcg tcaacttgcg tcagacattt cagcgcatgt tccaggacac tgggcatcgg
    14401 ctcctgcagg ccggtcagtt tcagcagcca ttgagtcccg ctggcactga acgacaattc
    14461 gacccctgcc tgacgtgcgt cctcccgggt ttcgcgcaga ctgcgttgca gcttcccgtg
    14521 cagatcggcc gttgccgctg cttccaactg ccagcgcagg taaatcgccc cttcgtcacc
    14581 gctgtccgcc aaggcctggc tgaattgcat cggcgagcgt tcgcggcggc tgcgtgagcg
    14641 atcctgagcg aacgtgcgca ggcctcggtg ggcgctggtt tgaccgcgaa tcagcccggc
    14701 gttggccagc ggctcgctgg aaccgaggaa agggttggcg gcaggcaggt gccaatgcgc
    14761 gctgaagtta tccacaacac cgatgtcgcg caggatctgt ttgagggcga cgacgccgtt
    14821 ttccgacaag ccgtgtccga gctgttcact gtcgaaccgc gccagttgca gtgcgccgct
    14881 gacctgctgc tgacgttcaa gcagcttggc gtactcctcg cgcaacgctg cccagtcctg
    14941 ctgtgcagcg aagaaactca gccaatccag cacctgttcg ccaacgacgt tcatggattc
    15001 cgtcggggca gtgaattgca gatgcagcaa agcttgtccg gcaaagtggt acagcggcgt
    15061 ggctttcagg ctgtccgcga ggttctgttg ctgcagatgt gcgagcaggc cgccgggctt
    15121 ggcgttgttc agccagtggc agaggaacgc cagcgcctcg atggaggcgt cgggcagcgc
    15181 ttcgaacgca aacagcagat tgcggtgctg cccgccgacc tgttgataac ttttcacctg
    15241 cagtggccgg gttgctgcct gcgcaacgtt attcccaatc ggcagcgctg cggcgaactg
    15301 ctgcgccatt gcgcgcaatg cttcgaggtt ttgcggcccg accaggctca aagtcatttg
    15361 gccgctgcga taaaaacgct gatggaaatc cttcaacgcc tgttgaaacg tcggttgctc
    15421 gaccttcagg ctgtcgcgat tgcctgcatg aaatccgcgc aacggatgcg ccgccggcaa
    15481 accctcgtac aaggagagtg cctgctgcgc cgtgggatcc tgcgaccacg cgacaaattc
    15541 cgcgtccagt acttcgcgtt cccgcaactg atcgtccgga ttcatacgcg ggtgggcgag
    15601 catgtctgac agacgctcaa gcccggcgcc gaaggccgag gtcggtaatt caaagaagaa
    15661 atcggtggtg cgctcgcggg tgctggcatt cacctgtccg ccatgacctt gcacgtaggc
    15721 catcagcgcc tgatcggcag gaaaacgctt ggtgccgaga aacagcaaat gctcaaggaa
    15781 atgcgccagc cccggccact cgagcggcac atcatgacta ccggcagcca cccgcaacgc
    15841 ggcggcgctg cgcttcaagc caggcacatg acgcagggtc acgcgcaggc cgttggccag
    15901 ggtttcagtg tgagggcggg ggtgagtcgg cgcaggcatg ggcacttcca gaacagtgaa
    15961 gtgccaatgc tagcggattg cgtggggtca gcgcttgttc agtgcgtcgt aaagctcggg
    16021 gcggcgatca ctgaggtagc gattggcggc gcgtgaatcg accatcaact gtcgatccag
    16081 ctccccgacg atcagcgctt catccaggcc ggcctgggcg atacggctgc cgtccggtgc
    16141 ggcgatgctg ctttgcccgc agtagtgaat ctcgccttcc tggccgcagt aattggcgta
    16201 ggccacgtag cactggtttt cgaaggcgcg ggaacgcacg gtcacgtcgg cgacgaaatc
    16261 gaacggaatc atgttcgccg tcggcaccag aatcagctcg gcgccggcca aggccagacg
    16321 ccgcgcgttt tccggaaact ccaggtcgta gcagatcagg aaaccgagct tccagccatt
    16381 gagctcgacc aacggaaagt catcctcacc ggggctgaac atcgaccggt ccagatcacc
    16441 gaacaggtgg gtcttgcggt aattgcacaa gcgttcgccg tgcgaatcga tcaactgcac
    16501 ggcgttgtag atctgcccgt cggcggtgcg ctccggataa ccgtacacaa tcgccagccc
    16561 ggcggctttg gcgattcgac cgatctgttg cgcccattcg ccgttgtaga cctcggccaa
    16621 cgtactgact gcctcggcgc cgatgttgta gccggtcaga aacatctccg gcaacaccag
    16681 caggtcagcg cccttggcct ccatcgccac ttggtgcaag cggtgcaggt tggcggcggg
    16741 gtccaggggc agcggtggac attggtaaag ggctacacgc atctcggatt cctcttactc
    16801 gggcagggcg atagggccga tgtctttgaa cacatcaccc gggcctgggt tctctttatg
    16861 tgtcgacccg ccgaaatgcc tcatgatgcc ccacaccgcg ttgagcgaag tctgcactgc
    16921 gccttcaacc cacgccggcg tccacgatac gtcgtctccg gcgatgaaaa tcccgcgctg
    16981 ttcggctggc atgtcgtcct gcatgaaatg cgcgtacatg cgctggttgt agcgatagtg
    17041 gccgggcagg gcacctttga acgcaccgag gaagtacggg tcggcttccc acgacacggt
    17101 gatcgggtcg ccgatgatcc gcgcagcgat gtcgacttta gggtagatct tcttcagcgc
    17161 gttcaacgcc agttccacac gtttttccac cgggtgcggc agcatcttca gcgcgtcgct
    17221 catccacgag tacgacaggc agatcacgcc gggcttgtcg tcgccgttgt cgaacagata
    17281 ggtgccacgg gtcaggcgat cggtgagggt catgctcatc aggtcgcggc cggtttccgg
    17341 atccttgtcc ttccagaacg ggcgatcgac catcacgaag gtcttcgacg attgcatgta
    17401 gcgcgtgcgg tccagcgcca tccacatctt ctgcgagaac agggtttcgt cgcattcgat
    17461 ctgggtggtc agcagccagc tctggcaggt ggtcagcacg gcggcgtatt cgcgggtgtc
    17521 gccgttgttg tcggtgacgg cgaaacggcc atccggggcg tgggcgattt tcttcacgcc
    17581 ggaacgcggc gcaccacggt gcagggattt caggctggtg ccttcaggcc agtgcacgca
    17641 acgctccggc acatgccgcc agatgccttg tggcacttgt tccacaccgc cgaccaccag
    17701 gtgctggtga tcgtcgcagt tggtcatcac cacgcggaag atttccagca tcgagttggg
    17761 gaagtccgag tcccagccgc cagtgccgaa accgacctga ccgaacactt cgcggtgatg
    17821 gaacgacaac ttggcgaagg ccttggaggt ggcaacgaaa tcgtagaacg tacggtcgtc
    17881 ccacagcggc acgagcgtgt tccacagctc cttgaggcgc ggcacatcgc ggtcgcgaat
    17941 ggcttgctgg atatcggaaa actgcgaacc ggcctccagt gcatctgccc aggcgtcagc
    18001 cacttcctgg aacaatgcag gaagatccgc cagtttctgt gcgtaatggg ttttgccttc
    18061 cagatcgatc accgtgctgc cggaggccgg tgtcagcggg ttagggaaag gcttggtctc
    18121 gaggccgagc ttgtcgacgt agtggtagaa cgcggtagaa gacaccggga aacgcatacc
    18181 gcccagttcc gcgacgatgc cgtcggtgcc attgaacgtt tgcgaacgca gacgcccacc
    18241 gagcttcgac gcctcataaa ccaccggttt caagccgagc ttcatcagtt cgtacgcggc
    18301 caccaggccg gcaataccgg cgccgacaat cgccacttca gcgccgtgat ggtgctcagg
    18361 aatgctgccg agaccggccg gatgttcgat ccagtcgtcg aaagcgaatg gaaagtccgg
    18421 accgaaaatg gtgacgggtt tcttaccgtc tgcaggatgg cgattgttct tgttcatggc
    18481 tgaccttgct ggcgacccga cgccgaatgc gcgtctgagt ataggaaaag atgccagcca
    18541 ttctagggag cgtagaacac gttaataaga cgcaaagtgt cgtcgttttg ataattaatc
    18601 gatcaatatg acgattgttg actacacacc gaccaaaatg taggagcgag cctgctcgcg
    18661 aagaggccct gtaatccacc caagaagacc ggacacaact ttaaaccggc tgcccccgat
    18721 caatcttgct actcaaaatg atcgacgtcg tcgtcttctc caccccgtcc acgctgccaa
    18781 tctgatccag caactggtcc agctgctccg gcgaatcggt gcgcaaccac gccacataat
    18841 caaattcgcc actcaccgca cacaactgct gcacctgcgc cattgcactc aagcggcgca
    18901 gcacttcttt gccggaacgc ggctgcacct tgatcccgac atacgcctgc aacccgccat
    18961 caaccacccg ctgccccaga cgcacgccat aaccggtgat gactttggcc ttttccagcc
    19021 gcgccagccg cgacgtgacg gtggtgcgcg caatgcccaa ctgccgggca agcatggcca
    19081 cgctctcgcg ggcgttgatc tgcagagcgg cgatcaactg gcggtcgatt tcatcaagca
    19141 cgggtgggcg gatgtctggc aaggggcggc tccatggggg gcgggtcttt gggcgagcat
    19201 gttacagcct caaccgactg gatatggaag ccccttatcg tagttggggt taaacgcaga
    19261 aacgaaaaag ccgcgcaatt gcgcggcttt cgaattggtg ggcccacacg gacttgaacc
    19321 gtggaccaaa ggattatgag tcctctgctc taaccaactg agctataggc cctcagtagg
    19381 tcgcggatta tagcgatggt ttctcggctg tgctatccga ataatccgat acggtaatac
    19441 gcagaaacgt tgcggcgaat tcttccgcgg gcagcggcag gctgacgatg tagccctgga
    19501 tctgttcaca gccctcggca gcgaggaatt gttgttgcgc ctgggtttcc acgccttcgg
    19561 caatcacggt gaattgcata ctccggccga gggcgatgat cgcccgtaca atcgccgcgt
    19621 cgtgggggtc gtcgggcagg ccgcggacga acgactggtc gatcttgagg atgtccagcg
    19681 gcaggcgttt gaggtagctg agcgaggaat agccggtgcc gaagtcgtcg atcgccagtt
    19741 gcacacccag gtgtttgagc tgatgcagca ccgccagtgc ttcttcggcc tggctcatga
    19801 tgaagttttc ggtaatttcc agttgcagta aatccggctg cagacgattt tccctgagca
    19861 gttgttcgat gcgcccgagc agattcggct ggcgcagttg tgcgccggcg aggttgaccg
    19921 acagcgggcc gaggctgtcg tagatctggt tccattcgaa catctgccgg caggcggtct
    19981 cgagcaccca gtcgccgatc tgcaggatca tgccgttctc ttcggccagc gggatgaagt
    20041 gctccggcgg cacctcgcca aaggccgggt ggcgccagcg aatcagcgct tcggcaccga
    20101 ccagacgatg gtcgtcgagg ctgatcttgg gttggtagta gagggacaat tcatcgcgtt
    20161 cgatggcccg gcgcagttcg tgttccagcg ctacgcgctc gctggcctgg gcggtgaggt
    20221 cgcgggtgta gctttcgacg cggttgcggc ccttggcctt ggagcggtac atcgccgcgt
    20281 cagcgttttt caccagcgtg gcaacgtcgc agccgtcgcg ggggtacagg ctggtgccga
    20341 tgctggcgct gatgaaaaac tcgtgttcgc cggcctggaa cggcgcgccg aagcagttga
    20401 gcagtttggt ggcaatgtga tcggcgtcgc tggcctgttg caggccgggc agcaggataa
    20461 tgaactcatc gccgcccagg cgcgcgacgg tatcgatgtc gcgcaattgt tccctcaggc
    20521 gaacggcaat gcctttgagc agcaagtcac cgaccgggtg cccgaggctg tcgttgatgt
    20581 gcttgaaacg gtcgagatcg aggaacagca cggcgccctg accgccgttt tcctgctggc
    20641 tgttcagtgc ggtgagcagg cgactttcaa acagcgtgcg attcggcagg ccggtgagcg
    20701 ggtcgtggtg cgcctgataa tcgagcttgg cttgcgcgtg tttaaggctg gagatatcgg
    20761 caaacaccgc gacgaagtgg gtgatgaact tgtcgcgatt gcgcacggcg ctgatggtca
    20821 gccagctcgg gtacagctcg ccgttcttgc gccggttgga aatctcgccc tgccagtgac
    20881 cctcgtcggt caactggtgc cacatcgccg cataaaacgc gctgtcgtgc agccccgagg
    20941 cgagcaggcg cggggtgtgg ccgagggctt cgctttcgct gtagccagtg atttcggtga
    21001 aggcgcgatt gaccgcgctg atgtgctgct gggtgtcggt gatcagcacg ccctcggcgg
    21061 tgctctcgaa tacggtggcc gcttgctgca gtttttcctg catcagatgg cgctcggtga
    21121 tgtcccgggc gatggtcagc atgcagtctt cttcgccgat cggtagcggt cgactggaca
    21181 cttcgcacag gcgaatctgc ccgtcgctgc ggcggatatg gcaggtgaag tcgcgtacga
    21241 agccgtcgcg gtgcagcagg tcgagcatct gtttgcgttc gttgaggttg acccagatcc
    21301 ccaggtccag cgccgaacga tccaccgaca tcgcgctgtt gaaaccggtg atgcggctga
    21361 atccctcgtt gacctccagc agcaggccat cgctttgccg tgacagcagc aagccgtccg
    21421 gcgaggcgtg gaaggccttg gcgaactttt cctcggacgt ttgcagttgc tgctgggttt
    21481 ccttgagctg ggtgatgtcg cgcaccacca ccaccagcgc cggggtggtg tcgaggtcga
    21541 acggctcggc ggagatcagg ccggtgaaca cctgaccgtt gctgcggcga aagggcatct
    21601 ccaggttgcg gatactgccg gcctgcaagc gctgtaacag gcccggcccg actcccggaa
    21661 tgccccagat gttgagctcg gtggcggtct ggccgacgac ttcctcggcc ttgaggccaa
    21721 tctgttcttc aaaggcttcg ttgacctcca gcaggcagcc gtcggacagc cgcgcgatca
    21781 ccagaatgtc cgggcattgc tggaacaccg acgcgaactt ctgctcagac aggcgcagcg
    21841 cttcttcggt gcgcttggtc tcgctgatgt cgatcatcag gccgcgcatc accggttcat
    21901 gcccgtgttc aatcaggctg acgatgtcgc gcacccacag gcagcgtccg tcagcggtga
    21961 tcacccgata gtcgagcgtg tgatcgcgcc cttcgcgcac cgcgtcatca caaatggtct
    22021 gggcacgggt caggtcggcg gggtggatga tgttgcgcca gaaacccgga atcagccaat
    22081 gcgcctgtgg ataaccgagc aggtcttcgg cgtggggcga cacatagctg taggtgaagt
    22141 cactcatgcg cgcttcc
//
