LOCUS       NZ_JAHFZZ010000037     27764 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Nonomuraea sp. NEAU-A123 Scaffold37, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZZ010000037
VERSION     NZ_JAHFZZ010000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea sp. NEAU-A123
  ORGANISM  Nonomuraea sp. NEAU-A123
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 90485)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Nonomuraea triticisoli sp. nov., a novel actinobacterium isolated
            from rhizospheric soil of wheat in Langfang, Hebei Province, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 90485)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, Changjiang Road No. 600, Xiangfang
            District, Harbin, Heilongjiang Province 150036, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603905.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 04:26:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,983
            CDSs (total)                      :: 11,901
            Genes (coding)                    :: 11,761
            CDSs (with protein)               :: 11,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 28 of 140
            Pseudo Genes (incomplete)         :: 121 of 140
            Pseudo Genes (internal stop)      :: 3 of 140
            Pseudo Genes (multiple problems)  :: 12 of 140
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:52:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 27764
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZZ010000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27764
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..27764
                     /SMILES="C(C)C(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27764
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2097:7764](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2098..7764
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(419..643)
                     /locus_tag="KLK06_RS55145"
                     /old_locus_tag="KLK06_55150"
     CDS             complement(419..643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629771.1"
                     /locus_tag="KLK06_RS55145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55150"
                     /product="hypothetical protein"
                     /protein_id="WP_214643907.1"
                     /transl_table=11
                     /translation="MKPPSAATRRHLPTSPFKPPPPAPPVEVFTLNDQVSHDRYGLGRV
                     IGVEDEAVLVDFGARQERITTPYAKLIKL"
     misc_feature    complement(664..680)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    734..747
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.56"
                     /tool="antismash"
     gene            complement(783..1871)
                     /locus_tag="KLK06_RS55150"
                     /old_locus_tag="KLK06_55155"
     CDS             complement(783..1871)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895177.1"
                     /locus_tag="KLK06_RS55150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55155"
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_214643908.1"
                     /transl_table=11
                     /translation="MRSHGLLALATTVLLIGSSATPALADPDWSIVPDGQTTTQPPAVR
                     PTTDSRPANYLPGQKALPGNARVVRERWLGPRMLDVLISSPSIGQLTPVRLLLPKGWSK
                     NASRTWPVLYLLHGGADNYTSWTRMTDIAGFTENLDAIVVMPEAGRAGNYSDWYNNGKG
                     GPPAWATFHTYEVRRLLEIGYRAGTRRAVAGLSMGAYGAMKYAARYPGMFRFVGAYSGV
                     MATQLPGIPEIIMNAQASEKQDPKALWGDPLRDRRVWAANDPVALAPGLKGVSIYISSG
                     TNSFLGPLDPPGSPWHPAHLGEPISAYTAKALSKRLNSLGIQHTLNLYGNGTHTWPYWI
                     REFKNSYPMILAALGLPGAVQP"
     misc_feature    1940..1955
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(1990..2007)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            2098..7764
                     /locus_tag="KLK06_RS55155"
                     /old_locus_tag="KLK06_55160"
     CDS             2098..7764
                     /NRPS_PKS="Domain: ACP (22-75). E-value: 4.5e-16. Score:
                     50.9. Matches aSDomain: nrpspksdomains_KLK06_RS55155_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (92-502). E-value:
                     8.3e-163. Score: 534.1. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55155_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (595-875). E-value: 1.5e-79.
                     Score: 259.4. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55155_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1218-1386). E-value: 3e-51.
                     Score: 165.9. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55155_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1453-1538). E-value: 1.6e-12.
                     Score: 39.6. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55155_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543618.1"
                     /locus_tag="KLK06_RS55155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55160"
                     /product="type I polyketide synthase"
                     /protein_id="WP_214643909.1"
                     /sec_met_domain="PP-binding (E-value: 2.6e-10, bitscore:
                     33.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7.7e-164, bitscore:
                     537.9, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.9e-88, bitscore:
                     287.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.1e-79, bitscore: 259.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.9e-46, bitscore:
                     150.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 7.1e-18, bitscore:
                     58.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVLGEAGIRRFLTERIASRGIERVDPERPLEEYGLSSRDAVAIA
                     GELAELLGRELSPTLAWEHPTINRLARALAAPPREREPETPGVLGEPVAVVGVGCRLPG
                     AHGPGAYWDLLLEGRDAVGEVPVGRWEAFDDGSARTEEVLARTTRQGGFLEDVAGFDAE
                     FFGIAPGEAALMDPQQRLLLETAWEALEHGGIAPRSLGGSRTGAFVGISSTEYAYLTST
                     DLAGVGAWTATGAALSIAANRLSYLLDLRGPSMAVDTACSSSLVAAHLAVGALRSGECD
                     LALAAGVNLLLSPLVTVAFDQGGGTAADGRCKAFDASADGMVRAEGCGVVVLKRLADAE
                     RDGDRVLAVITETGVNQDGRSNGLVAPNPEAQEALLREVYAGLDRGPDYVEAHGTGTFL
                     GDPIEARAIAAVFPGQVLLGSAKTNLGHLEAAAGIAGLIKTVLALWHGVIPPSLHFRQP
                     NPHIPWETLRVVTTPTPWPRPDARAGVSSFGFGGTNAHVALAAYRAQEAAAVARAVPAK
                     HIFVLTGTTPDRVGQHAETLAAWQPSADLRDVAHTLARRAGHGRSATAVLAADAPELRE
                     RLAAVTPRPVPPAPVGPVWVFSGYGSQWQGMGHHLYETEPPYRQAIDELAPLLQAEAAI
                     DLHTPAAAPGVATVQPMIFAVQIALARLWQAYGIEPAAVIGHSMGEAAAAVVAGGLDLP
                     DAVRVICRRARLLGTVGSGTGAMAVVGVGAEEVPGDLYVAVHSAPSQTVVTGAPERIAR
                     FVAEVEASGLFARTLTTEGAGHSPQVAPLLPKIRAELVAITPAKPRLPYYSTVFDDPRE
                     TPTFEAAYWAAGVRRPVRLLQAVRAAAEDGFTVFTEVSPHPLLSPALQDTLPATTMITH
                     SLERRHDHAFHTQLATVATAITPRTRGQVVDVPGAPWQHTRHWVTPYCRPPGHRLLGAY
                     VESPAGHSWTTTLDDLADAPWRLEPSGWHRHGHPVLPLTAVARLAHAAATEVYGSAELY
                     EVALHALLPLPARVTVTLTGTGVELAAKNAAGSWTVYGSAGLTRTVRPADALERVRRVA
                     ADGTLHGVESREVPASSIPVPLDDKLLERVWVPAPLPAAPAAGGSGAIVRVPRLLDPRA
                     ARRLILDLARRADQGTELTIVTERAQAVRDGEAADPGPASVSGLVRVLAFERPEARVRL
                     VDVDDLNVLAQELAADSGDDEVAWRDGARYAARLRRATLGTVFHPSVVGPGGYVITGGY
                     GRLGLVVARWLASRGATRIVLNGRSAAPVPSDLEGVAEVVVGDLAAHGTAERLVAAATD
                     GGVRLRGVVHAAGVLDDRLIADLDPGSLQRVWAAKVDGALHLHQATEHLDLDWWVAFSS
                     AAALLGSPGQAAYATANAWLDALCRLRRARGLPAVAIGWGTWAGAVAMPGIEPLTAEEG
                     VEALEALIQRDRCAGVVRFAPAAALSVFPGIGRLPYFSEVAGHLASEGPRDLAELGPEE
                     ALAAVVGQVRERVAAVLGVEPVWLDEGAVLTGRGLDSLAATRLRGTIEYDFGVTIPTAP
                     LLNGGTLGDLARTVATELGLTQPEPARAVVGPRDAAERQVVRVLTGLLGRVPSVTETIA
                     PDVLATTLDLLSHELGRTVETGGGVRVAEVADAVRQGEVAEAGLAVVRPLTARTGDRPL
                     FLAHPAGGTTGGYALLAARLDLPVIGLERLDGAGELGIPERAARYAEAVKQTCPGPYRL
                     GGWSFGGTLAFEIARRLDDDVELVAMIDAGLPARVSEERRREIQAQRYADFATYLHHTY
                     GVQVRLDQRELRLLDERGQLALAEERIAESGVPALLSPAILRHQITSHEDTRALDRYEA
                     GPYQGEVVLYRSTEPTPWTVEDVRYAHEDDPARGFRPYSPRLEIVEIPGSHHLNLLDPP
                     HVEGIADDLKRRLA"
     aSDomain        2164..2322
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55155_ACP.1"
                     /evalue="4.50E-16"
                     /label="KLK06_RS55155_ACP.1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="75"
                     /protein_start="22"
                     /score="50.9"
                     /tool="antismash"
                     /translation="ERVDPERPLEEYGLSSRDAVAIAGELAELLGRELSPTLAWEHPTI
                     NRLARALA"
     aSDomain        2374..3603
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55155_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="8.30E-163"
                     /label="KLK06_RS55155_PKS_KS.1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="502"
                     /protein_start="92"
                     /score="534.1"
                     /tool="antismash"
                     /translation="VAVVGVGCRLPGAHGPGAYWDLLLEGRDAVGEVPVGRWEAFDDGS
                     ARTEEVLARTTRQGGFLEDVAGFDAEFFGIAPGEAALMDPQQRLLLETAWEALEHGGIA
                     PRSLGGSRTGAFVGISSTEYAYLTSTDLAGVGAWTATGAALSIAANRLSYLLDLRGPSM
                     AVDTACSSSLVAAHLAVGALRSGECDLALAAGVNLLLSPLVTVAFDQGGGTAADGRCKA
                     FDASADGMVRAEGCGVVVLKRLADAERDGDRVLAVITETGVNQDGRSNGLVAPNPEAQE
                     ALLREVYAGLDRGPDYVEAHGTGTFLGDPIEARAIAAVFPGQVLLGSAKTNLGHLEAAA
                     GIAGLIKTVLALWHGVIPPSLHFRQPNPHIPWETLRVVTTPTPWPRPDARAGVSSFGFG
                     GTNAHVALAAY"
     aSModule        2374..6711
                     /complete
                     /domains="nrpspksdomains_KLK06_RS55155_PKS_KS.1"
                     /domains="nrpspksdomains_KLK06_RS55155_PKS_AT.1"
                     /domains="nrpspksdomains_KLK06_RS55155_PKS_KR.1"
                     /domains="nrpspksdomains_KLK06_RS55155_PKS_PP.1"
                     /locus_tags="KLK06_RS55155"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2851..2898
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0001"
                     /evalue="4.70E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="267"
                     /protein_start="251"
                     /score="21.6"
                     /tool="antismash"
                     /translation="GPSMAVDTACSSSLVA"
     CDS_motif       3040..3078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0002"
                     /evalue="9.50E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="327"
                     /protein_start="314"
                     /score="12.4"
                     /tool="antismash"
                     /translation="FDASADGMVRAEG"
     CDS_motif       3262..3309
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0003"
                     /evalue="4.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="404"
                     /protein_start="388"
                     /score="12.4"
                     /tool="antismash"
                     /translation="YVEAHGTGTFLGDPIE"
     CDS_motif       3352..3396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0004"
                     /evalue="3.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="433"
                     /protein_start="418"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GSAKTNLGHLEAAAG"
     CDS_motif       3877..3933
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0005"
                     /evalue="1.00E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="612"
                     /protein_start="593"
                     /score="17.9"
                     /tool="antismash"
                     /translation="VWVFSGYGSQWQGMGHHLY"
     aSDomain        3883..4722
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55155_PKS_AT.1"
                     /evalue="1.50E-79"
                     /label="KLK06_RS55155_PKS_AT.1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="875"
                     /protein_start="595"
                     /score="259.4"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFSGYGSQWQGMGHHLYETEPPYRQAIDELAPLLQAEAAIDLHTP
                     AAAPGVATVQPMIFAVQIALARLWQAYGIEPAAVIGHSMGEAAAAVVAGGLDLPDAVRV
                     ICRRARLLGTVGSGTGAMAVVGVGAEEVPGDLYVAVHSAPSQTVVTGAPERIARFVAEV
                     EASGLFARTLTTEGAGHSPQVAPLLPKIRAELVAITPAKPRLPYYSTVFDDPRETPTFE
                     AAYWAAGVRRPVRLLQAVRAAAEDGFTVFTEVSPHPLLSPALQDTLPATTMITHSLER"
     CDS_motif       4033..4095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0006"
                     /evalue="1.40E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="666"
                     /protein_start="645"
                     /score="21.1"
                     /tool="antismash"
                     /translation="VATVQPMIFAVQIALARLWQA"
     CDS_motif       4099..4209
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0007"
                     /evalue="1.50E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="704"
                     /protein_start="667"
                     /score="52.3"
                     /tool="antismash"
                     /translation="GIEPAAVIGHSMGEAAAAVVAGGLDLPDAVRVICRRA"
     CDS_motif       5752..5847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0008"
                     /evalue="5.10E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="1250"
                     /protein_start="1218"
                     /score="41.6"
                     /tool="antismash"
                     /translation="YVITGGYGRLGLVVARWLASRGATRIVLNGRS"
     aSDomain        5752..6255
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55155_PKS_KR.1"
                     /evalue="3.00E-51"
                     /label="KLK06_RS55155_PKS_KR.1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="1386"
                     /protein_start="1218"
                     /score="165.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="YVITGGYGRLGLVVARWLASRGATRIVLNGRSAAPVPSDLEGVAE
                     VVVGDLAAHGTAERLVAAATDGGVRLRGVVHAAGVLDDRLIADLDPGSLQRVWAAKVDG
                     ALHLHQATEHLDLDWWVAFSSAAALLGSPGQAAYATANAWLDALCRLRRARGLPAVAIG
                     WGTWA"
     CDS_motif       6100..6210
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0009"
                     /evalue="1.30E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="1371"
                     /protein_start="1334"
                     /score="62.7"
                     /tool="antismash"
                     /translation="LDWWVAFSSAAALLGSPGQAAYATANAWLDALCRLRR"
     aSDomain        6457..6711
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55155_PKS_PP.1"
                     /evalue="1.60E-12"
                     /label="KLK06_RS55155_PKS_PP.1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="1538"
                     /protein_start="1453"
                     /score="39.6"
                     /tool="antismash"
                     /translation="LAELGPEEALAAVVGQVRERVAAVLGVEPVWLDEGAVLTGRGLDS
                     LAATRLRGTIEYDFGVTIPTAPLLNGGTLGDLARTVATEL"
     CDS_motif       7174..7239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55155_0010"
                     /evalue="1.70E-13"
                     /label="NRPS-te1"
                     /locus_tag="KLK06_RS55155"
                     /protein_end="1714"
                     /protein_start="1692"
                     /score="42.8"
                     /tool="antismash"
                     /translation="GPYRLGGWSFGGTLAFEIARRL"
     gene            7761..9053
                     /gene="ccrA"
                     /locus_tag="KLK06_RS55160"
                     /old_locus_tag="KLK06_55165"
     CDS             7761..9053
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (48-398). E-value: 2.4e-27.
                     Score: 87.8. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55160_PKS_ER.1"
                     /codon_start=1
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895175.1"
                     /locus_tag="KLK06_RS55160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55165"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_214643910.1"
                     /sec_met_domain="ADH_N (E-value: 1.8e-09, bitscore: 29.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.3e-26, bitscore:
                     82.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAEAVVAGAGPAELASLEVPTRYRAVHLRKDEVGMFGDMSDKD
                     VRKSLHVGEVPMPELAPDEVLVAVMASAINFNTIWSAMFEPIPTFAFLERFGRTDPRHD
                     LPTHVLGSDAAGVVVRTGQAVRHWRAGDRVVTSPAYLDSQDPIVQHDGMLAADLRAWGF
                     ETNFGGLAEFAVVKATQLLPKPRHLSWEEAACNMLCASTAYRMLVGERGARMKQGDVVL
                     LWGASGGLGAYGVQLVRNGGGIPVGVVSSPEKAALLRRMGCAHVVDRSRFDDLTDEKGW
                     RGLGAEIRRQVGEDPAIVFEHTGRDTFGASVYVAKKGGKVVTCGSSSGYDHAYDNRHLW
                     MRLKQIIGSHGANYQECHEVNRLISLGMIHPTLSRAYPLAEAADAARAVQLNQHVGKVG
                     VLALAPGPDLGIEDAAHRERIGEDRLRLFRS"
     aSDomain        7905..8954
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55160_PKS_ER.1"
                     /evalue="2.40E-27"
                     /label="KLK06_RS55160_PKS_ER.1"
                     /locus_tag="KLK06_RS55160"
                     /protein_end="398"
                     /protein_start="48"
                     /score="87.8"
                     /tool="antismash"
                     /translation="SLHVGEVPMPELAPDEVLVAVMASAINFNTIWSAMFEPIPTFAFL
                     ERFGRTDPRHDLPTHVLGSDAAGVVVRTGQAVRHWRAGDRVVTSPAYLDSQDPIVQHDG
                     MLAADLRAWGFETNFGGLAEFAVVKATQLLPKPRHLSWEEAACNMLCASTAYRMLVGER
                     GARMKQGDVVLLWGASGGLGAYGVQLVRNGGGIPVGVVSSPEKAALLRRMGCAHVVDRS
                     RFDDLTDEKGWRGLGAEIRRQVGEDPAIVFEHTGRDTFGASVYVAKKGGKVVTCGSSSG
                     YDHAYDNRHLWMRLKQIIGSHGANYQECHEVNRLISLGMIHPTLSRAYPLAEAADAARA
                     VQLNQHVGKV"
     CDS_motif       8088..8126
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55160_0001"
                     /evalue="3.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="KLK06_RS55160"
                     /protein_end="122"
                     /protein_start="109"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LGSDAAGVVVRTG"
     gene            complement(9061..10251)
                     /locus_tag="KLK06_RS55165"
                     /old_locus_tag="KLK06_55170"
     CDS             complement(9061..10251)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895174.1"
                     /locus_tag="KLK06_RS55165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55170"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_250907540.1"
                     /transl_table=11
                     /translation="MASKSDTSDTRISADIVKTLKAGIGRISAEVIGEIQARIPEYARP
                     SDEVYIKVVRTTVEQAIDGFLDHIQDPAAPWDPEPFRMIGKGEAAEGRNLEPLQAAMRL
                     GARVGWRRLTEIADPLGLSPQSLYDLGEAIFVYLDQLADAAAEGFDEARAHAAGEIERR
                     RNRLLDLLLSRPPAGSEAISDLARAAGWRLPKTVACVALDDQHGTCRSPAVPPDVLTGL
                     ERTTPCLLVPDPNGPGQARMLETALRGYLGAIGPAVPLPAAASSLRWAAEALELSGRGV
                     LPRGLLRCTDHMATLVVFKDEELVNALAEIRLAPLAHLRPTQQDRLAETLLAWLRHGRG
                     AGEVAARLHVHPQTVRYRLRQLEELYGDQLADPDIRFELEIVLRARRAAALAARPL"
     misc_feature    10303..10319
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     gene            complement(10311..10511)
                     /locus_tag="KLK06_RS55170"
                     /old_locus_tag="KLK06_55175"
     CDS             complement(10311..10511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016188830.1"
                     /locus_tag="KLK06_RS55170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55175"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_214643911.1"
                     /transl_table=11
                     /translation="MSTDYTITFDLIDVDKDGRISAEELVGLMEVLGQPITLEAAQAGV
                     QRLDKDGDGLIDVEEFGAFLK"
     gene            complement(10541..11419)
                     /locus_tag="KLK06_RS55175"
                     /old_locus_tag="KLK06_55180"
     CDS             complement(10541..11419)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="KLK06_RS55175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55180"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_214643912.1"
                     /transl_table=11
                     /translation="MDVHLRDLRYFVATAEELNVTRAAERLFVSQPALSKQLRALERQL
                     GFGLFERVPSGMVLTRQGETLLPVARELLDRWNAGLETARAAAPTGTLVIGMQTAVGRG
                     IQQEALRLFRKAMPGWEVSLRLVGWDDPSGGLADGGSDVAFIWLPVPEGLNTHVLATEG
                     RGVAMPDDHPLAELAEIPFEALRDEPFIALPTSAGPLRDYWLARDLRDDEPVIGVTANT
                     PEEVFEAVTSGLGVVLVAEGNAALYKRPGLVYRPVTGLPPGELAIAWRSGDKRPEVRAF
                     IDALRESATKV"
     gene            11482..12465
                     /locus_tag="KLK06_RS55180"
                     /old_locus_tag="KLK06_55185"
     CDS             11482..12465
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019608469.1"
                     /locus_tag="KLK06_RS55180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55185"
                     /product="aldo/keto reductase"
                     /protein_id="WP_214643913.1"
                     /transl_table=11
                     /translation="MKTRELGNNLRVPAIGFGAMVLSPGVYGDIDDTRAETALKAALDA
                     GAVHVDTSDAYGANGHNERLVGRAIKGRRDEVVVATKFGLAIPEGEASRSQPVGYAFGE
                     LRVNAEPRMVRRYAERSLRNLDTDVIDLYYSHYVDPGVPIEETAGAMAELVEAGLVRHL
                     GLSNVTADELRRAHAVHPVAAVQNEWSMWRPVDPDLLKAARELNVGIVAWSPLGNGFLT
                     GTVQQLGEGDFRHNAPRFSAGNLASNNDRYAPIRDLATRLGITPAQLALAWLLHQYEHV
                     VAIPGSRTPVHIEENLAAADLVLHRDTLAQVDEALAGFEVTGGTLL"
     gene            12466..14160
                     /locus_tag="KLK06_RS55185"
                     /old_locus_tag="KLK06_55190"
     CDS             12466..14160
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543612.1"
                     /locus_tag="KLK06_RS55185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55190"
                     /product="alpha-amylase family protein"
                     /protein_id="WP_250907541.1"
                     /sec_met_domain="Alpha-amylase (E-value: 7.4e-69, bitscore:
                     225.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDPLLGSGGGMRLTYTSDLWWKNAVVYCLDVETFKDGNDDGIGD
                     FRGLTQQIDYLAGMGVTTLWLMPFFPTPNRDDGYDITDFYSIDPRLGTLGDFVEFMRTA
                     KDRGLRVIADLVVNHTSDQHPWFIESRSSKKSPLRDWYVWSDKPEPDDPKQVVFPDEED
                     SIWQLDTSTGQYYLHSFYRHQPDLNVSNPEVRDEIVRILGFWMELGLSGFRVDAVPFLI
                     ENVQPKLADPHEFLADLRAFMTRREGTSVLLGEVNLPYKDLMSYFGEGLGDQLSMCFDF
                     IGMQRAWLALARGEAEPLADALKSRPRPPKDCQWAMFLRNHDELTLDKLTDKERQEVFR
                     AFGPDEDMQIYGRGLRRRLPTMMGGDPRRIKMAYSLLFSLPGTPVMFYGEEIGMGENLK
                     TEGRMAVRTPMQWSVDGGFTRGAPEREMPDGAYSPARINVADQKRDRDSLLRWFQLLIE
                     RYRECPELAWGDCTVLEAADPAILAHRCDADGATVVVIHNLGETAQDVELKLAGLESHT
                     LTDLLVDGTVEVSEQGVAQLTLEPHGCRWLRASPKEIPAEDASVKSL"
     gene            14216..15958
                     /locus_tag="KLK06_RS55190"
                     /old_locus_tag="KLK06_55195"
     CDS             14216..15958
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894011.1"
                     /locus_tag="KLK06_RS55190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55195"
                     /product="bifunctional UDP-sugar hydrolase/5'-nucleotidase"
                     /protein_id="WP_214643914.1"
                     /transl_table=11
                     /translation="MHIIKFGAVTLTALALIGLPAHATGGKTITVTVMGTSDIHGNGLN
                     WDYYKDTAYADSAGNNVGLAKVSTLVNKVRTERGADRTLLFDSGDTIQGTPLAYYYAKV
                     EPITRNGPVHPMAKAMNAIGYDAVTLGNHEFNYGLPLLATWIHQMKAPVLGANAVSAKT
                     GRPAYLPFVIKTMNVKGDKPVKVGVLGLTNPGVAIWDKANVEGKLRFTDLVESAKKWVP
                     IIRKLGADVVVVTAHAGDSGISSYGGDLPVENASAMVAEQVPGIDAVLFGHAHNDVAQR
                     FVTNQATGKQVLLTEPSKWGQRLSVIDFQLAKQGGKWTVTGKSSTTLNTNTAAEDPKIT
                     ALLKPQHDATVGYVNKVVAKSSEQLSAAESPYKDTPILDYIQQVQVETVKQALPDNQLP
                     ILSIAAPFSRTAVFPAGDIRVRDVAGLYVYDNTLLAVKLTGAQIKDYLEYSAKYFNQLA
                     SGDPVDVAKLTNAGNTPDYNYDQLSGVSYDIDIAKPVGQRIANLTYEGTPVPADKEFVV
                     AINNYRQSGGGGFPHVVGAPVLYNAQVEIRQALIDYATAKGTINPADFAAANWRLTRDG
                     APVF"
     gene            complement(16041..16781)
                     /locus_tag="KLK06_RS55195"
                     /old_locus_tag="KLK06_55200"
     CDS             complement(16041..16781)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543608.1"
                     /locus_tag="KLK06_RS55195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55200"
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="WP_214643915.1"
                     /transl_table=11
                     /translation="MEILILAFFALGYLVLAGADIGVGMVLPYLGRTAGERREAIAAIA
                     PFFLGNEVWLVATAGVLAGLFPALEGSLLSGNYSLVVALVLSWVLRDMGLWLRGRLPGV
                     RWQGFWDGAVVTGSWGLALSWGWLLSDVLLGIHGPIAVLPALLVAALFATHGLAFATLR
                     LRGVLRARAAVLSGGAGEGRTYALTATALVAIGVLAGFRLPLAPGTSGALLVPVILTMI
                     PFLVASQAWVWWTFRHRVSEPSYL"
     misc_feature    complement(16491..16493)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16791..18041)
                     /locus_tag="KLK06_RS55200"
                     /old_locus_tag="KLK06_55205"
     CDS             complement(16791..18041)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543607.1"
                     /locus_tag="KLK06_RS55200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55205"
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="WP_214643916.1"
                     /transl_table=11
                     /translation="METVDLARLQFALTAGAHFLFVALTLGLATLVAVIQTRATLTRSP
                     VHLRMTRFWGQLYIINYAMGIVTGLVMEFQLGLSWSGLTEFAGNVFGSALAIETIVAFF
                     IESTFLGLWIFGWNKLNRWAHLALIWVVTLTAHASAFWILISNGFLQNPVGYQLKDGVL
                     RLTDFGALVANPAALIAFFHVGGGALIVGGFLMAGVSAYHLAKRTAEQDFFRKSLRLGI
                     GVALPATLFTATFGGIGFQTLQPTKLAAWSGSANRLAEAQAEMAAKYGPGDYLPPLGWV
                     HAGGITMLTLFAVLFFVAGVSFLLMLFRPVVRGFRPWHRLLTALIPVPFVTMIAGWIFR
                     EMGRQPWTVYGLLKTADAMSPVSSGQIRFSLTAFGTVFAVLILVNYWLLARTARKGPNA
                     VTLGDRPLALGAPTLTF"
     gene            complement(18138..18806)
                     /locus_tag="KLK06_RS55205"
                     /old_locus_tag="KLK06_55210"
     CDS             complement(18138..18806)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017539452.1"
                     /locus_tag="KLK06_RS55205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55210"
                     /product="response regulator transcription factor"
                     /protein_id="WP_214643917.1"
                     /transl_table=11
                     /translation="MIRTVLADDQNLVRAGFRSILSDEDGIEVVGEAANGAEAVARTRE
                     LRPDVVLMDIRMPELDGLEATRVIVTDPRLDGVKVIILTTFDLDDYVYGALRAGASGFL
                     VKDTEPAELIHAVRVVARGDALIAPSVTRRLIAEFAGRVKRPEPGPRLNALTEREREVM
                     ALVAAGLSNDEIAARLVLSPATAKTHVSRIMTKLGSRDRAQLVVLAYEAGMITPGWLTP
                     "
     gene            complement(18803..19927)
                     /locus_tag="KLK06_RS55210"
                     /old_locus_tag="KLK06_55215"
     CDS             complement(18803..19927)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895154.1"
                     /locus_tag="KLK06_RS55210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55215"
                     /product="sensor histidine kinase"
                     /protein_id="WP_250907542.1"
                     /transl_table=11
                     /translation="MRTLSAGTIVSLAVVVAVLAGTVVTSFLQPGHVPNALDVLLPLAA
                     GAGVLARQRYPVAALIVVLVAVALYYPFARLDGPVIILAFVVLYTAAELGHLIAAIAAG
                     AAALLAMGLGETGGIRHMDDSVFLMIAGWVVAAVAGGGVTRNRRAYLREAERRVLDALH
                     SKEEEARLRASEERLRIARELHDVLGHNISMINVQAAAALHGLKKRPQDAEAALRTIKE
                     TSKETLRELRTTLGVLRQVDEGAPTAPADSLARMEALVAGTGVDVRTELSGRLDGVPTE
                     VDLAATRIIREALTNVSRHSGAAEARLSVTNQSGHIVIRVEDDGPGATFTDGSGFGLQG
                     MRERAGALGGTLEAGPRPDGGFLVVADLPLNGVR"
     gene            19993..20205
                     /locus_tag="KLK06_RS55215"
                     /old_locus_tag="KLK06_55220"
     CDS             19993..20205
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS55215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_55220"
                     /product="hypothetical protein"
                     /protein_id="WP_214643918.1"
                     /transl_table=11
                     /translation="MSVEDELRQVEEDLTRLRAQTKDLRDQIGDMGATDQVEVGAMISM
                     ADEQEELIADLERRRDDLLRRRDGG"
     gene            complement(20219..21232)
                     /locus_tag="KLK06_RS55220"
                     /old_locus_tag="KLK06_55225"
     CDS             complement(20219..21232)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017579038.1"
                     /locus_tag="KLK06_RS55220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55225"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_308168952.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 8.6e-21,
                     bitscore: 66.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADTGTLETRGSDFAKLARQIQDAGLLDRRPIYYAVRLTLVLAAY
                     VGLWALFWWVGDSWWQLLVAVALGVASAQIGFVAHDLGHRQVFRTRRASDILGLLIGDF
                     GIGLGWGWWNTKHNRHHANPNHEDEDPDVSPAVIVWSTDQVRRSRGLPRFIAKWQAFWF
                     FPLLTLEAWHLHIASVKAVFQPTTKHRKWEGALLLAHFVCYFGVIFTVLPIGMALVFLV
                     VHQGLFGVYLGSTFAPNHKGMPILTKDDKLDYLRKQVLTSRNVKGGVFVDVALGQLNYQ
                     IEHHLFPNMPSPNLRKAQPIVRQYCADLGVSYLETGLIASYGQALRHLHEVGAPLR"
     gene            21439..22761
                     /locus_tag="KLK06_RS55225"
                     /old_locus_tag="KLK06_55230"
     CDS             21439..22761
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547335.1"
                     /locus_tag="KLK06_RS55225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55230"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_214643919.1"
                     /transl_table=11
                     /translation="MTHVLIVGSGPTGLTLAIELARRGVDRRIVERSAEPPTGVRGKGL
                     QPRTLEVFDDLGVIDEILATGSGYPGIRSYKGDQIVWEGRMDEPKEPSPGIPYPNLIMQ
                     PQWRTERILRDRLAELGHRVEFGSEVTGFEQDEQGVTATLSGGETVRCAYLVGADGGRS
                     TIRKQLGVGFAGETYESERMLLADVKTGDLDRDFWHIWGSMEEQVMYFGLCPLPHTDVF
                     QLVAPYTGEDDLRALVARHAPHVHLDEILWRSDYRANVRMAERFRVGRVFLAGDAAHVH
                     SPAGGQGLNTGVQDAYNLGWKLAIGSAALIDTYEDERMAVAAHVLGLSTRLHRERDIER
                     GDNTNQLDLAYLGSALSMGERGGERLGTLFAEQRGTHFLLLGATGREYGDAIRVLPPLD
                     GQEGVILVRPDGYIGYHGDESGLSAYLSGFGIDAPLTRASS"
     gene            complement(22683..25565)
                     /locus_tag="KLK06_RS55230"
                     /old_locus_tag="KLK06_55235"
     CDS             complement(22683..25565)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="KLK06_RS55230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55235"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_214643920.1"
                     /transl_table=11
                     /translation="MRIGILGPLQVAGAAVGGARVRGLLVRLALDPGRVVTTDRLIDDL
                     WPGEPPEHPMAALQSLVSRARREAPGLISSHPNGYLLDVPADEVDAWAFERLARAGDAH
                     AALALWRGPALAGVDLPFAEAPAARLEELRLAALATRIAADLAAGGNVIGGGIAGGEVV
                     GGDVVAELEELVAEHRLREPFHALLMRAMVANGRRGEALEVFERIRAELADELGVDPGA
                     ELREAHLAALRDEEPAPRTNLPARLTSFVGRNDDVSRIRTLTGARLITLVGPGGAGKTR
                     LAVEAAATLRVPDGVWLVELAPAAGVRAALEAVLKTSDLVKALRGTSPVIVLDNCEHLI
                     DEAARVAQWLLGEVAGLRIIATSREPLNIPGESLHPVLPLPEEPAVELLRDRAAAARPD
                     LVLAPAEAARICRELDGIPLAIELAAARLRTMSVSMLVEQLGDRLAFRGSRTSEPRHRT
                     LRAVIDWSWNLLSEEERELLRGLSVFSGGATAEAIARICGGDLELLSSLVDKSLIAVSG
                     DRYTMLETIRQYVTGDFPEVRQAHARYYAELAEAAEPHLRTGEQVKWLAVLDAEQGNLD
                     AALRHSDDPLRVILPRLWPWMMRGRRHEIAAHATAVLRRVGDVAPEGRELAHGLCMMAA
                     MGAEPTRAVLESDHPAALHSWAMVVALGPPRDVVAITEAGAARLRDHPDTWTRSTALLV
                     AGIVRFEYGAVAGAESLLEPALDGLRRTGDRWGQWTAYFWLSLAAENRGDFARALVLAK
                     EPEPIAAELAALGAPLGPMMFLLRLGQLMMRSGDHAGAATALERAWQAALRSEDPLTIA
                     RVTHARAELARRSGDRGEAARLLRSALAMNIDAPPQFRAFMNVELARVAEPAEPLRRAL
                     ELMVTCEDRTARATVLEGVAEHREPLTAAELLGAARLLRGITESADPFVVALAGRCRAA
                     LGEERYEEALVRGASMPNPERYALSPLSSP"
     misc_feature    complement(24426..24428)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25652..26629
                     /locus_tag="KLK06_RS55235"
                     /old_locus_tag="KLK06_55240"
     CDS             25652..26629
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (42-240). E-value:
                     1.3e-11. Score: 36.0. Matches aSDomain:
                     nrpspksdomains_KLK06_RS55235_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009083560.1"
                     /locus_tag="KLK06_RS55235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55240"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_214643984.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.3e-08, bitscore:
                     26.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLLTGSAGFIGSHIAEAVDRLGHEVVPADVRTGVDVRDEVALN
                     RLLPGTDAVVHQAAKVGLGVNVADLPGYASVNVYGTAVLLAAMARHGVGRLVLASSMVV
                     YGEGAYDCLAHGRVRPGPRRSSDLAGGLFDPRCPTCDAVLAPAVIAEDAPLDPRNAYAT
                     TKLAQEHLSANWARETGGTAVALRYHNVYGPRMPRDTPYAGVASIFLSALVAGRAPRVF
                     EDGGQRRDFVHVRDVARANVLALDAGTAGALTPYNIASGIPRTVGDLATALAEQTGGPE
                     PVTTGEYRLGDVRHIVASPARAAAELGFAAEIGFGDGIKEFATL"
     CDS_motif       25661..25705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS55235_0001"
                     /evalue="1.70E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="KLK06_RS55235"
                     /protein_end="18"
                     /protein_start="3"
                     /score="1.5"
                     /tool="antismash"
                     /translation="LLTGSAGFIGSHIAE"
     aSDomain        25778..26371
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS55235_NAD_binding_4.1"
                     /evalue="1.30E-11"
                     /label="KLK06_RS55235_NAD_binding_4.1"
                     /locus_tag="KLK06_RS55235"
                     /protein_end="240"
                     /protein_start="42"
                     /score="36.0"
                     /tool="antismash"
                     /translation="ALNRLLPGTDAVVHQAAKVGLGVNVADLPGYASVNVYGTAVLLAA
                     MARHGVGRLVLASSMVVYGEGAYDCLAHGRVRPGPRRSSDLAGGLFDPRCPTCDAVLAP
                     AVIAEDAPLDPRNAYATTKLAQEHLSANWARETGGTAVALRYHNVYGPRMPRDTPYAGV
                     ASIFLSALVAGRAPRVFEDGGQRRDFVHVRDVARA"
     gene            complement(26654..27043)
                     /locus_tag="KLK06_RS55240"
                     /old_locus_tag="KLK06_55245"
     CDS             complement(26654..27043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017575693.1"
                     /locus_tag="KLK06_RS55240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55245"
                     /product="VOC family protein"
                     /protein_id="WP_214643921.1"
                     /transl_table=11
                     /translation="MRINLASVLVDDQEKALRFYTEVLGFVKKHDVPLGEDRWLTVVSP
                     QDPDGTELVLEPSSHPAVQPFKEALVADGIPYTSFAVDDVKSEYERLRGLGVRFTQEPA
                     DMGPVTTAVLDDTCGNLIQIAHQAG"
     gene            complement(27040..27342)
                     /locus_tag="KLK06_RS55245"
                     /old_locus_tag="KLK06_55250"
     CDS             complement(27040..27342)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152876.1"
                     /locus_tag="KLK06_RS55245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_55250"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_214643922.1"
                     /transl_table=11
                     /translation="MVRRVGDVFKALADSTRRTILDELTDRDGQTLFEICARLATKHGL
                     GSSRQAVSQHLDVLEAAGLVETRREGRYKFHYINTSPLEPIIERWLTKPEKREPA"
ORIGIN
        1 ctctgctccg ccgggccatg accaacttcg ctgtcaccga cctggccggt ctcgtccgga
       61 tcgtcaaacg caagctgaag aagatccaat accggcccca cctgctcacc ggctgcctgg
      121 cccagaccgg actcaccctc gataccccga caaagccatg accgactcta cgaattcaac
      181 ctgtgtagca cgaactggcc agacggcttg ggcccgggga gcgcgagggg ccaaacggcc
      241 acctcgccgg aagtgtgggg acttgtcccc actatcaccg cctgagctcc atcggcgctg
      301 agcgcctgaa ggcgatgacc atgctttcat gggccgggcc cgtatgacac gcgtcaagac
      361 atgctgacag cgccctctgg cgaacgctgc ctgcgggttc ctgtactgcc aggctgtctt
      421 agagcttgat cagcttggcg tacggggtcg tgatccgttc ctggcgggca ccgaagtcga
      481 caagcacggc ttcgtcctcg acgccgatga cccgaccgag accgtaccgg tcatgggaca
      541 cctggtcgtt caaggtgaac acctcgaccg gcggggccgg gggcgggggt ttgaaggggc
      601 tggtgggcag gtggcgccgg gtcgcggcgc tgggcggctt catctactcc agtatgcgcc
      661 accctgagat cttagaacgc cacattcgcc gcagtggtta ggttttcggg cgtgaaaacc
      721 ggggaaaacc agccaaatgt ccgttttaag ggcgtccgga aagccgtcgc gccgcgtgct
      781 gttcagggct ggacggcgcc tggcaggccc agtgcggcca agatcatggg gtaggagttc
      841 ttgaactccc tgatccagta cggccaggtg tgggtgccgt tgccgtacag gttcagggtg
      901 tgctggatgc ccaggctgtt cagccgcttg ctcagggcct tggccgtgta ggcggagatg
      961 ggttcgccga ggtgggccgg gtgccagggg gagccgggcg ggtccagggg gccgaggaag
     1021 ctgttcgtgc cgctcgagat gtagatcgag acgcccttca ggcccggggc cagggccacg
     1081 gggtcgttgg ccgcccagac cctcctgtcg cgcagggggt cgccccagag ggccttgggg
     1141 tcctgcttct cgctggcctg ggcgttcatg atgatctcgg ggatgccggg gagctgggtg
     1201 gccatgacgc cgctgtacgc accgacgaag cggaacatcc ccggatagcg tgccgcgtac
     1261 ttcatcgccc cgtacgcacc catcgacagc ccggcgacgg ctcgacgggt gcccgcgcgg
     1321 tagccgatct ccagcagccg ccgcacctcg tacgtgtgga acgtggccca cgccggtgga
     1381 ccgcccttgc cgttgttgta ccagtctgag tagttaccgg ctcggcctgc ttccggcatg
     1441 acgactatgg cgtccaggtt ctcggtgaag ccggctatgt ccgtcatgcg ggtccaggac
     1501 gtgtagttgt cggcgccgcc gtgcaggagg tacaggacgg gccaggttcg gctcgcgttc
     1561 ttggaccagc ccttggggag cagcaggcgg accggcgtca actggccgat cgacggtgag
     1621 gagatgagaa cgtcgagcat gcgggggccc agccaccgct cccgcacgac gcgggcgttg
     1681 ccggggagag ccttctggcc gggcaggtag ttcgcgggcc gggagtccgt tgtgggccgt
     1741 acggccggtg gctgggtggt cgtctggccg tcgggcacga tcgaccagtc tggatcggcg
     1801 agcgcgggag tggcgctcga cccgatgagg agcaccgtcg tcgccagtgc cagcaggccg
     1861 tgggatcgca tgagggctcc ccttcgcaag tgagaccgtg gcgaggctag gggccacggc
     1921 accgccccag ctatgaccca atgcaacgaa atatcgtcgt tggttgcgct ctgccggaca
     1981 aaaccggggt tatcaccggc gtgacaaatc gcacccgagg aatgttcggt acggggctgc
     2041 cccagcgccg gagggcgcgg gtatgttggc cgaccacccg gcagcatggg agccctcgtg
     2101 aacgtactgg gtgaagccgg catccgccgc ttcctcaccg aacggatcgc ctcacgcgga
     2161 atcgagcggg tcgatccgga acggccgctg gaggagtacg gcctgtcgtc gcgtgacgcg
     2221 gtggcgatcg cgggcgagct ggccgaactg ctcggcaggg agctcagccc gaccctcgcc
     2281 tgggaacacc cgacgatcaa ccgcctggcc cgcgcactcg ccgcgccgcc gcgggaacgc
     2341 gagccggaaa cccccggcgt gctcggggag ccggtggcgg tggtcggggt ggggtgccgg
     2401 ttgccgggcg cgcacggccc gggggcgtac tgggacctgc tgctcgaagg gcgagacgcg
     2461 gtcggcgagg tgcccgtggg ccggtgggag gcgttcgacg acgggtcggc gcgcacggag
     2521 gaggtgctgg ccaggacgac caggcagggc gggttcctgg aggacgtggc ggggttcgac
     2581 gcggagttct tcgggatcgc gccgggcgag gcggccctca tggatccgca gcagcggctg
     2641 ctcctggaga cggcctggga ggcgctggag cacggcggca tcgccccgag gtcgctgggc
     2701 ggcagccgta ccggggcgtt cgtcggcatc tccagcaccg agtacgccta cctgaccagc
     2761 acggacctgg ccggcgtcgg cgcgtggacg gccaccggcg cggcgctcag catcgccgcg
     2821 aaccgcctgt cctacctcct cgacctgcgc ggcccctcga tggcggtgga cacggcctgc
     2881 tcgtcctcgc tcgtcgccgc ccacctcgcg gtaggcgcgc tgaggtcggg ggagtgcgac
     2941 ctggccctgg ccgccggagt gaacctgctg ctgtctcccc tggtcacggt ggcgttcgac
     3001 cagggcggcg gcacggcggc ggacgggcgg tgcaaggcgt tcgacgcgtc ggccgacggc
     3061 atggtgcgcg ccgagggctg cggcgtcgtc gtactcaaac gcctggcgga cgccgaacgg
     3121 gacggcgacc gggtgctcgc ggtgatcacg gagaccggcg tcaaccagga cggccgctcg
     3181 aacggcctcg tcgccccgaa ccccgaggcg caggaagcgc tgttgcgtga ggtgtacgcg
     3241 gggctggacc gggggcccga ctacgtggag gcgcacggaa ccggcacgtt cctcggcgac
     3301 cccatcgagg cgcgggccat cgccgcggtg ttccccggac aggtgctgct cggctcggcc
     3361 aagacgaacc tcggccacct ggaggcggcg gccgggatcg cggggctcat caagacggtc
     3421 ctggcgctgt ggcacggcgt gatcccgccc agcctgcact tccggcagcc gaacccgcac
     3481 attccctggg agacgctgcg ggtcgtcacc acgcccacac cttggccgcg accggacgcg
     3541 cgagcggggg tgtcgtcgtt cggcttcggc ggcaccaacg cgcacgtcgc tctggcggcg
     3601 taccgggcgc aggaggccgc ggcggtcgcc cgagccgtcc ccgccaagca catcttcgtc
     3661 ctcaccggca ccactcccga tcgcgtcggg cagcacgcgg agaccctggc cgcctggcag
     3721 ccctcggccg acctccgcga cgtggcccac accctcgcca ggcgagccgg tcacggtcgc
     3781 agcgccaccg ccgtgctggc cgccgacgcg cccgagctgc gcgaacgact cgccgccgtc
     3841 acccctcgcc ccgtcccccc ggctccggtc gggccggtgt gggtcttcag cgggtacggc
     3901 tcgcagtggc aggggatggg ccaccacctg tacgaaacgg aaccgcccta cagacaggcg
     3961 atcgacgaac tcgcccccct cctccaggcc gaagccgcca tcgacctcca caccccggcg
     4021 gcggccccgg gcgtcgccac ggtccagccc atgatcttcg ccgtccagat cgccttggcc
     4081 cgcctgtggc aggcgtacgg catcgaaccc gccgcggtga tcggccactc gatgggcgag
     4141 gcagcggccg cggtcgtggc aggcggcctc gacctgcccg acgcggtacg ggtgatctgc
     4201 cgccgcgccc gcctcctcgg caccgtcggc agcgggactg gggccatggc cgtggtcggg
     4261 gtgggtgccg aggaggtgcc cggtgacctg tacgtggcgg ttcattccgc gccgagccag
     4321 accgtcgtca ccggtgcccc cgagcggatc gcccggttcg tggcggaggt cgaggccagc
     4381 ggtctgttcg ccagaacgct caccaccgaa ggcgccggcc attcacccca ggtcgccccc
     4441 ttgctgccga agatcagggc cgagctcgtc gccatcaccc cggccaagcc gcgcctgccg
     4501 tactactcca cggtcttcga cgacccccgc gagaccccca cgttcgaggc cgcgtactgg
     4561 gccgcgggcg tgcgccgccc ggtacgcctg ctccaggctg tacgggccgc cgcggaggac
     4621 ggtttcaccg tcttcaccga ggtgagcccg caccccttgc tgagcccggc gctccaggac
     4681 acgctcccgg ccaccacgat gatcacccac tccctcgaac gccgtcacga ccacgccttc
     4741 cacacccagc tcgccaccgt ggccaccgcc atcacgccca ggacgcgggg ccaggtggtg
     4801 gacgtaccgg gagcgccgtg gcagcacacg cgccactggg tcaccccgta ctgccgccca
     4861 ccgggacacc gcctgctcgg cgcgtacgtc gagtcccccg ctggacactc gtggaccacc
     4921 acgctcgacg acctcgccga cgcgccctgg cggctggagc cgtccggctg gcatcgccac
     4981 ggccaccccg tgctcccgct caccgccgtg gcccggctcg cgcacgccgc cgccacggag
     5041 gtgtacggat cggcggagtt gtacgaggta gccctgcacg cgttgctgcc cctgcccgcg
     5101 cgggtgacgg tcacgttgac ggggaccggg gtcgagctgg cggccaagaa cgccgcaggc
     5161 tcctggacgg tctacggctc ggccggcctc acgcggacgg ttcggccggc tgatgccctg
     5221 gagagggtac ggcgggtggc ggcggacggc acgctccacg gggtcgagag ccgggaggtc
     5281 ccggcgtcca gcatcccggt gcccctcgac gacaagctcc tcgaacgcgt ctgggtcccc
     5341 gcccccttgc cggcggctcc ggcggccggt gggtcgggtg ccatcgtgcg ggtgccgcgg
     5401 ctgctcgatc ctcgggcggc tcgacggctg atcctggatc tggcccgccg cgccgaccag
     5461 gggacagagc tcacgatcgt caccgaacgc gctcaggccg tacgagacgg agaggcggcc
     5521 gatcccggtc ccgcctcggt gagcgggctg gtcagggtgc tggcgttcga gcgccccgaa
     5581 gcgcgcgtca ggctggtgga cgtcgacgac ctcaacgtcc tggcccagga actcgccgcc
     5641 gacagcgggg atgacgaggt ggcctggcgt gacggcgcgc gctacgcggc ccggctgcgc
     5701 cgcgcgacac tcggcacggt gttccatccg tcggttgtgg ggcctggcgg gtatgtgatc
     5761 accggtgggt acggcaggct cgggctggtc gtcgcgcgct ggctggccag tcgtggtgcc
     5821 acgcgcatcg tgctgaacgg ccgctccgcc gctcccgtgc cgagtgacct cgagggcgtc
     5881 gccgaggtgg tggtgggtga tctggctgct cacggtacgg ccgagcggct cgtggcggct
     5941 gcgaccgacg gaggggtacg gctacgcgga gtcgtacacg ccgccggagt cctggatgac
     6001 cggctgatag ccgatctcga cccgggcagc ctccaacggg tctgggccgc caaggtggat
     6061 ggcgcgctcc accttcacca agccaccgaa cacctggacc tcgactggtg ggtggccttc
     6121 tcctcggccg ccgcgctgct cggctcccct ggccaggccg cttacgccac cgccaacgcc
     6181 tggctggacg ccctctgccg gttgcgtcgt gcgcgggggc tgcccgccgt cgccattggc
     6241 tggggtacgt gggccggggc ggtcgcgatg ccggggatcg agccgctgac cgctgaggag
     6301 ggtgtcgagg cgttggaggc gttgatccag cgtgaccggt gtgcgggggt ggtcaggttc
     6361 gctccggccg cggctttgtc ggtgtttccg gggatcggtc gccttccgta cttctcggag
     6421 gtcgccggcc acctcgcctc ggaggggccg cgtgatctcg ccgagctggg gcccgaggag
     6481 gcgctggccg ccgtcgtggg gcaggtcagg gagcgggtcg cggccgtgct cggggtggag
     6541 ccggtgtggc tggacgaggg cgccgtgctc accgggcggg ggctcgactc gctggccgcc
     6601 acccggttgc gtggcacgat cgagtacgac ttcggcgtca cgatcccgac ggcaccgctg
     6661 ctcaacggcg gaacgctggg cgacctggca cggaccgtcg ccaccgaact gggcctcaca
     6721 cagcccgaac cggcacgcgc tgtggtcggg ccgagggacg cggcggagcg gcaggtggtc
     6781 agggtgctga ccggcctgct cggacgcgtg ccctcagtca ccgagacgat cgcgccggac
     6841 gtgctggcga caaccctcga cctcctcagc cacgaactcg gcagaacggt cgagacaggc
     6901 ggcggggtcc gggtggccga ggtcgccgat gccgtgcgcc agggcgaggt cgccgaggcc
     6961 gggctcgccg tcgtcagacc cctcaccgca cgcaccggcg accggccgct gttcctggcg
     7021 caccccgccg gtggcaccac aggcgggtac gccctgctgg ccgcccgcct ggacctcccg
     7081 gtcatcggcc tggagcggct ggacggcgcg ggcgagctgg gcatccccga gcgggccgcc
     7141 cgctatgccg aggccgtcaa gcagacctgt cccgggccct accggctggg cggctggtcg
     7201 ttcggaggga ctctggcgtt cgagatcgcc aggcggctgg acgacgacgt cgagctggtc
     7261 gcgatgatcg acgccgggct gccggccagg gtgtccgagg agaggcggcg ggagatccag
     7321 gcccagcggt acgccgattt cgcgacatat ctgcatcaca cctacggcgt ccaggtccgc
     7381 ctcgaccagc gcgaactccg gctgctcgac gagcgcggac agctcgcgct ggccgaggag
     7441 cggatcgcgg agtccggcgt gccggccctg ctcagcccgg ccatcctgcg ccaccagatc
     7501 acctcgcacg aggacaccag ggccctcgac cggtacgagg ccgggccgta ccagggcgaa
     7561 gtggtcctct accgttccac ggagccgacc ccctggacgg tcgaggacgt gcggtacgcg
     7621 cacgaggacg atccggcgcg cggcttccgc ccttacagcc cgcgcctgga gatcgtcgag
     7681 attcccggct cgcaccacct caacctgctc gacccacccc acgtcgaagg catcgccgac
     7741 gacctgaaga ggaggctcgc atgacgctgg cagaggccgt ggtggcgggc gcggggcccg
     7801 cggagctggc gagcctggag gtgccgacac gctaccgggc tgtacacctc cgcaaggacg
     7861 aggtcggcat gttcggcgac atgagcgaca aggacgtacg gaagtccctg catgtggggg
     7921 aggtgccgat gccggagctg gcgcctgatg aggttcttgt cgcggtcatg gccagtgcga
     7981 ttaatttcaa cacgatctgg tcggccatgt tcgagccgat cccgacgttc gcgttcctgg
     8041 aacgcttcgg gcgtaccgac ccgcggcacg atctgcccac ccacgtgctc ggctccgacg
     8101 cggccggggt ggtcgtcagg acggggcagg cggtacggca ctggcgggcc ggggaccggg
     8161 tggtcaccag ccccgcctac ctcgacagtc aggacccgat cgtgcagcac gacgggatgc
     8221 tggccgcgga cctgcgcgcg tgggggttcg agacgaactt cggcgggctg gcggagttcg
     8281 cggtggtcaa ggcgacgcag ttgctgccca agccgcggca tctgagctgg gaggaggcgg
     8341 cgtgcaacat gctgtgcgcg tcgaccgcgt accggatgct ggtcggcgag cgcggcgccc
     8401 ggatgaagca gggcgacgtg gtgctgctgt ggggagcgtc gggcgggctc ggcgcgtacg
     8461 gcgtgcagct cgtcaggaac ggcggcggca tccccgtcgg cgtggtgagc tccccggaga
     8521 aggccgcgct gctgcgccgg atgggctgcg cgcacgtcgt cgaccgctca cgcttcgacg
     8581 acctgaccga cgagaagggg tggcgcgggc tgggggcgga gatcaggcgc caggtgggtg
     8641 aggacccggc catcgtgttc gagcacaccg gaagggacac tttcggcgcg tcggtatatg
     8701 tcgcgaaaaa gggcgggaag gtggtcacct gtgggtcgtc cagcgggtac gaccacgcct
     8761 acgacaaccg gcacctgtgg atgcggctca agcagatcat cggctcccac ggcgcgaact
     8821 accaggaatg ccacgaggtt aaccgcctca tctcgctcgg catgatccat cccacgctct
     8881 cccgcgcgta cccgctggcc gaggcggcgg acgccgcgcg ggccgtccag ctcaaccagc
     8941 acgtggggaa ggtcggcgtg ctggccctgg cccccggccc ggacctcggc atcgaggacg
     9001 ccgcccaccg cgagcgcatc ggcgaggacc gtctccggct gttccgttcc tagaaaagac
     9061 tcacaaaggg cgtgcggcca gggcggccgc ccggcgggca cgcagcacga tctccagctc
     9121 gaagcggatg tccggatcgg cgagctggtc cccgtaaagc tcctccaact gccgcaaccg
     9181 ataccgaacc gtctgcggat gcacatgcag ccgagccgcc acctcccccg ccccccggcc
     9241 gtgccgcagc caggccagca gcgtctccgc cagccggtcc tgctgcgtgg gccgcagatg
     9301 ggccagcggc gccagccgta tctccgccag tgcgttgacc agctcctcgt ccttgaacac
     9361 gaccagcgtc gccatatggt ccgtgcagcg cagcaggccg cgcggcagca cgccgcgccc
     9421 ggacagctcc agtgcctcgg ccgcccaccg cagcgacgac gcggcggcgg gcaggggcac
     9481 ggcgggcccg atcgcgccca ggtagccgcg gagcgcggtc tccagcatcc gggcctggcc
     9541 ggggccgttc gggtcgggta cgagcaggca tggcgtggtt cgttccaggc cggtcagcac
     9601 gtcgggcggc accgcggggg accggcaggt gccgtgctgg tcgtcgagcg cgacgcaggc
     9661 cacggtcttc ggcagccgcc acccggcggc cctggccagg tcggagatgg cctccgaacc
     9721 ggcgggcggc cggctcagca gcaggtcgag cagccggttg cggcgccgct cgatctcgcc
     9781 cgccgcgtgt gcccgagctt cgtcgaagcc ctcggccgcg gcgtcggcga gctggtcgag
     9841 gtagacgaag atggcctcgc ccaggtcgta cagggactgc ggggagagtc cgagcgggtc
     9901 ggcgatctca gtcagccgcc gccagccgac ccgggcgccc agccgcatcg cggcctgcag
     9961 cggctccaga ttgcgaccct ccgccgcctc gcccttgccg atcatgcgga acggctcggg
    10021 gtcccagggg gcggcggggt cctggatgtg gtcgaggaag ccgtcgatgg cctgctcgac
    10081 ggtggtcctg acgaccttga tgtagacctc gtcggatggc cgggcgtact cggggatgcg
    10141 ggcctggatc tccccgatca cctcggcgga gatccggccg attccggcct tgagcgtctt
    10201 cacgatgtcc gcggagatcc gggtgtcgct ggtgtcactc ttgctggcca tcgtccctcc
    10261 tgtcgccatt gttacccgcg cggcagaggt ttgtgtagca agtgcttgtt ttacttcagg
    10321 aaggcgccga actcttccac gtcgatcaag ccgtccccgt ccttgtcgag ccgctgcact
    10381 ccggcctgcg ccgcctccag cgtgatcggc tgacccagca cctccatcag tcccaccagc
    10441 tcttcggcgg agatcctgcc gtccttgtca acgtcgatca ggtcgaaagt gatcgtgtaa
    10501 tcggtgctca tgggtcgccc tttcgcgaga tccgtgtcgg tcagacctta gtagcgcttt
    10561 ctcggagtgc gtcgatgaat gccctgactt ctggcctttt atcgccggac cgccaggcga
    10621 tggccagctc gcccggcggg aggccggtca ccgggcgata gaccaggccg ggccgtttgt
    10681 agagcgcggc gttgccctcg gccaccagga cgacgcccaa accgctggtc acggcctcga
    10741 acacctcttc aggcgtgttg gccgtgaccc cgatgaccgg ctcgtcgtcc cggaggtcgc
    10801 gggcgagcca gtagtcgcgc agcggccccg ccgaggtggg cagcgcgatg aacggctcgt
    10861 cgcgcagggc ctcgaacggg atctccgcca gctcggcgag ggggtggtcg tccggcatgg
    10921 cgacgcctct gccctcagtg gcgagaacat gcgtgttcag tccctcgggc acgggcagcc
    10981 agatgaaggc cacgtcggag ccgccgtcgg ccaggccgcc gctgggatcg tcccagccga
    11041 ccagccgcag tgacacctcc cagccgggca tcgccttccg gaacaggcgc agcgcctcct
    11101 gctggatccc tcgcccgacc gccgtctgca tgccgatgac cagggtgccc gtgggtgcgg
    11161 cggcccgtgc ggtctcaagc ccggcgttcc accggtcgag cagttcgcgc gcgaccggca
    11221 gcagcgtctc gccctgcctg gtcaggacca tcccggaggg cacgcgctcg aacaggccga
    11281 agccgagctg ccgttccagc gccctgagct gcttggacag cgcgggctgg gagacgaaca
    11341 gccgctcggc ggccctagtc acgttcagct cctcggccgt cgcgacgaaa taacgcaggt
    11401 cccgcaggtg cacgtccata accatcggtt atagcagtag gtcttggacg tgccgcccgt
    11461 accgccagca ggatgaaccg catgaagaca cgtgaactcg gaaacaacct gcgggtcccc
    11521 gcgatcggct tcggcgcgat ggtgctgtcg cccggcgtgt acggcgacat cgacgacacc
    11581 cgcgccgaga cggcgctcaa ggcggcactc gacgccggag cggtccacgt cgacaccagc
    11641 gacgcctacg gtgcgaacgg ccacaacgag cgcctggtcg gccgggcgat caagggccgg
    11701 cgcgacgagg tggtggtcgc caccaagttc ggcctggcca tcccggaggg ggaggcgagc
    11761 agatcgcagc ccgtgggcta cgcgttcggc gagctgcggg tgaacgccga gccgcggatg
    11821 gtccgccgct acgccgagcg gagcctgcgc aacctggaca ccgacgtgat cgacctctac
    11881 tactcgcact acgtggaccc gggcgtgccg atcgaggaga cggccggggc gatggccgag
    11941 ctcgtcgagg ccgggctggt caggcacctc ggcctgtcga acgtgaccgc agacgagctg
    12001 cgccgggcgc atgccgtgca cccggtggcg gccgtgcaga acgaatggtc gatgtggcgg
    12061 ccggtcgatc ccgacctcct caaggcggcc cgcgagctga acgtgggcat cgtggcctgg
    12121 agcccgctcg gcaacggctt cctcaccggc accgtccagc agttgggcga gggcgacttc
    12181 cggcacaacg cgccccgctt ctccgccggc aacctggcga gcaacaacga tcgttacgcc
    12241 ccgatcaggg acctggccac ccgcctgggc atcacccccg cccaactggc cctggcctgg
    12301 ctgctgcacc agtacgagca cgtggtggcg atcccgggca gccgcacccc cgtgcacatc
    12361 gaggagaacc tggccgccgc cgacctcgtc ctgcaccgcg acacactggc ccaggtcgac
    12421 gaggcgctcg ccggattcga ggtgaccggc ggcaccctgc tctgaatggg tgacccgctc
    12481 ctgggtagcg gtggcggcat gcgactgacg tacacctcgg atttgtggtg gaagaacgcc
    12541 gttgtctact gcctggacgt cgagacgttc aaggacggca acgacgacgg gatcggcgac
    12601 ttccgcgggc tcacgcagca gatcgactac ctggcgggga tgggggtcac caccctgtgg
    12661 ctgatgccgt tcttcccgac ccccaaccgg gacgacggct acgacatcac cgacttctac
    12721 tccatcgacc cccggctcgg cacgctgggc gacttcgtag agttcatgcg gaccgccaag
    12781 gaccgcggcc tgcgggtgat cgcggacctg gtcgtgaacc acacctccga ccagcacccc
    12841 tggttcatcg aatcgcggtc gagcaagaag tcgccgctgc gcgactggta cgtctggtcg
    12901 gacaagccgg agccggacga tcccaagcag gtggtcttcc ccgacgagga ggacagcatc
    12961 tggcagctcg acacctcgac cggccagtac tacctgcaca gcttctaccg ccaccagccc
    13021 gacctgaacg tcagcaaccc cgaggtgcgc gacgagatcg tccggatcct gggcttctgg
    13081 atggagctgg ggctgtcggg gttccgggtg gacgccgtgc cgttcctcat cgagaacgtc
    13141 cagcccaagc tggccgaccc gcacgagttc ctggcggacc tgcgggcctt catgacccgg
    13201 cgtgagggca cctcggtgct gctcggcgag gtcaacctgc cctacaagga cctgatgagc
    13261 tacttcgggg aggggctggg cgaccagctc tccatgtgct tcgacttcat cggcatgcag
    13321 cgcgcgtggc tggcgctggc gcgcggcgag gccgagccgc tcgccgacgc gctcaaatcc
    13381 cggcccaggc cgcccaagga ctgccagtgg gcgatgttcc tgcgcaacca cgacgagctg
    13441 acgctggaca agctcacgga caaggaacgc caggaggtct tccgggcatt cggcccagac
    13501 gaggacatgc agatctacgg ccgcggcctg cgccggcgct tgccgaccat gatgggcggg
    13561 gacccgcgcc gcatcaagat ggcctacagc ctgctcttct ccctgccggg cacgcccgtc
    13621 atgttctacg gcgaagagat cggcatgggc gagaacctca agacggaggg ccgcatggcc
    13681 gtacggacgc cgatgcagtg gtcggtggac ggcggcttca cccggggcgc ccccgaacgc
    13741 gagatgccgg acggcgccta ctcgcccgcg cggatcaacg tggccgacca gaagcgggac
    13801 cgggattcgt tgctgcgctg gttccagctg ctcatcgagc gctaccgcga gtgcccggag
    13861 ctggcctggg gcgactgcac agtgctggag gcggccgatc cggcgatcct ggcgcaccgc
    13921 tgcgacgccg acggcgccac ggtggtggtg atccacaacc ttggcgaaac cgcccaggac
    13981 gtggagctga aactggccgg gctggagtcg cacacgctca cggacctcct ggtggacggg
    14041 acggtggagg tctccgagca gggcgtggcg cagctgacgc tggagccgca cggctgccgc
    14101 tggctacgcg cctccccgaa ggagatcccc gcggaggacg cctcggtcaa gtccctctga
    14161 cccggccagg tttcccgtaa cccgtgggtt atttgccgga gttagcctcc tcgccatgca
    14221 catcatcaag tttggggccg tcacgctgac cgcgctggcc ctgatcggcc tgcccgcgca
    14281 cgcgaccggt ggcaagacca tcaccgtcac cgtgatgggc acctccgaca tccatggcaa
    14341 cggcctcaac tgggactact acaaggacac ggcctacgcg gacagcgccg gcaacaacgt
    14401 cggcctggcc aaggtgtcga cgctggtcaa caaggtgcgg acggagcgcg gcgccgaccg
    14461 gacgctgctg ttcgactcgg gtgacaccat ccagggcacc ccgctggcgt actactacgc
    14521 caaggtcgag ccgatcacca ggaacggccc ggtccacccg atggccaagg ccatgaacgc
    14581 catcggctac gacgccgtca ccctgggcaa ccacgagttc aactacggcc tgcccctcct
    14641 ggccacctgg atccaccaga tgaaggcccc ggtactcggc gcgaacgcgg tcagcgcgaa
    14701 gaccggccgg cccgcctacc tgccgttcgt gatcaagacc atgaacgtca agggcgacaa
    14761 gccggtcaag gtgggcgtgc tcggcctgac caacccgggt gtcgcgatct gggacaaggc
    14821 gaacgtcgag ggcaagctcc gcttcaccga cctggtggag tcggccaaga agtgggtgcc
    14881 gatcatccgc aagctgggcg cggacgtggt cgtggtgacc gcgcacgcgg gcgacagcgg
    14941 catctcgtcc tacggcggtg acctgcccgt ggagaacgcc tcagcgatgg tcgccgagca
    15001 ggtgccgggc atcgacgcgg tgctgttcgg gcacgcgcac aacgacgtgg cccagcgatt
    15061 cgtcacgaac caggccaccg gcaagcaggt cctgctcacc gagccgagca agtggggcca
    15121 gcgcctcagc gtgatcgact tccagctggc caagcagggc ggcaaatgga ccgtcaccgg
    15181 caagtcctcg accacgctca acacgaacac ggccgccgag gacccgaaga tcaccgctct
    15241 gctcaagccg cagcacgacg ccacggtcgg ctacgtcaac aaggtcgtgg ccaagtcgtc
    15301 ggagcagctc tcggccgccg agtccccgta caaggacacg ccgatcctcg actacatcca
    15361 gcaggtccag gtcgagaccg tcaagcaggc gctgccggac aaccagctgc cgatcctgtc
    15421 gatcgccgcg ccgttcagcc ggaccgccgt cttccccgcc ggtgacatcc gggtccgcga
    15481 cgtggccggc ttgtacgtgt acgacaacac gctgctggcc gtgaagctga cgggcgccca
    15541 gatcaaggac tacctggagt actccgccaa gtacttcaac cagctcgcct ccggcgatcc
    15601 cgtggacgtc gccaagctga ccaacgccgg gaacacgccg gactacaact acgaccagct
    15661 gtcgggcgtc tcgtacgaca tcgacatcgc caagccggtc gggcagcgga tcgcgaacct
    15721 cacctacgag ggaacgccgg ttccggcgga caaggagttc gtggtcgcga tcaacaacta
    15781 ccgccagtcg ggtggcggcg ggttcccgca cgtcgtgggc gcgccggtgc tgtacaacgc
    15841 ccaggtggag atccgccagg cgctgatcga ctacgcgacc gcgaagggca cgatcaaccc
    15901 ggccgacttc gccgccgcca actggcgcct gacgcgtgac ggcgcgccgg tcttctgacg
    15961 tacggcaagc agcggatccg caaatggcct ggccgctcct tgacaggcgt ggcggcgtca
    16021 tccctccaga tttccgccgc tcaaaggtaa gacggctcgc tcacccggtg ccggaaggtc
    16081 caccagaccc acgcctgtga ggccaccagg aacgggatca tcgtgaggat gaccggtacc
    16141 agcagtgcgc ccgaggtccc cggcgccagt ggcagccgga agcccgccag gaccccgatc
    16201 gccacgaggg ccgtcgcggt cagggcgtag gtgcggccct ccccggcgcc gccggacaac
    16261 accgccgccc gcgcacgcag cacgccccgc agccgcagcg tcgcgaaggc cagcccgtgc
    16321 gtggcgaaca acgcggccac cagcagggcg ggcagcaccg cgatgggccc gtggatgccg
    16381 agcagcacgt cactgagcag ccaaccccag ctcaacgcca gcccccagct accagtgacg
    16441 accgcgccgt cccagaaccc ctgccaccgg acgcccggca gccgcccgcg taaccacaga
    16501 cccatgtccc gcaggaccca ggagagcacc agcgccacga cgagcgagta gttgccgctc
    16561 agcaacgagc cctccaaagc ggggaagagc ccggcgagga cccccgcggt ggccaccagc
    16621 cacacctcgt tgccgaggaa gaagggcgcg atcgcggcga tggcctcgcg ccgctcgccg
    16681 gcggtgcgcc cgaggtacgg cagcaccatg ccgacgccga tgtcggcccc ggccagcacg
    16741 aggtagccga gcgcgaagaa ggccaggatc aggatctcca tgacggctcc tcagaaggtc
    16801 agggtggggg cgccgagcgc aagtggccgg tcgcccagcg tgacggcgtt cggtcccttg
    16861 cgggcggtcc tggccagcag ccagtagttg accaggatga gcacggcgaa cacggtgccg
    16921 aacgcggtca gcgaaaacct gatctggccg ctggacaccg gtgacatggc gtcggccgtc
    16981 ttcagcaggc cgtacacggt ccagggctgg cggcccatct cgcggaagat ccacccggcg
    17041 atcatggtca cgaacgggac ggggatcagc gcggtcagca gccggtgcca gggccggaag
    17101 ccccgtacga ccggccggaa cagcatcagc aggaaactca ccccggcgac gaagaagagc
    17161 accgcgaaga gcgtcagcat ggtgatcccg ccggcgtgca cccagcccag cggcggcagg
    17221 tagtcacccg ggccgtactt ggccgccatc tccgcctgcg cctcggccag ccggttcgcg
    17281 ctgcccgacc aggcggccag cttggtgggc tgcagcgtct ggaagccgat gccgccgaac
    17341 gtcgcggtga acagcgtcgc gggcagcgcc acgccgatcc cgaggcgcag cgacttgcgg
    17401 aagaagtcct gctcggcggt gcgcttggcc aggtggtagg cgctcactcc ggccatcagg
    17461 aagccgccga cgatcagcgc gccgccgccg acgtggaaga aggcgatcag cgccgccggg
    17521 ttggccacca gcgcgccgaa gtcggtgagc cgcaggacgc cgtccttgag ctggtagccc
    17581 accgggttct gcaggaagcc gttggagatc aggatccaga acgccgaggc gtgggccgtc
    17641 agcgtgacga cccagatcag cgccaggtgc gcccaccggt tcagcttgtt ccagccgaag
    17701 atccacaggc ccaggaaggt ggactcgatg aagaacgcca cgatcgtctc gatcgccagc
    17761 gccgagccga acacgttccc ggcgaactcg gtgagcccgc tccacgacag cccgagctgg
    17821 aactccatga ccagtccggt gacgatgccc atcgcgtagt tgatgatgta cagctgcccc
    17881 cagaaccggg tcatccgcag gtgcaccggg ctgcgggtca aggtggcccg ggtctggatg
    17941 acggccacca gcgtcgccag cccgagggtc agcgcgacga acaggaagtg cgcccccgcg
    18001 gtgagggcga actgcaggcg ggcgaggtcg acggtctcca tggtcagagg ttcccgtcaa
    18061 gaccacctcc accgcgtcat gccagggcat acacctgctg tacacctgtg gtgtcaacgg
    18121 accgcccggc gtacacctca gggagtaagc cagcccgggg tgatcatgcc ggcctcgtag
    18181 gcgagcacca cgagctgcgc ccggtcgcgc gagccgagct tggtcatgat gcggctgacg
    18241 tgcgtcttgg ccgtggccgg gctgagcacc agccgggccg cgatctcgtc gttggacagc
    18301 ccggccgcga ccagcgccat gacctcccgc tcgcgctcgg tgagcgcgtt gagcctggga
    18361 cccggctccg ggcgcttgac ccggccggcg aactcggcga tcagccgccg ggtgaccgag
    18421 ggcgcgatca gcgcgtcccc cctggccacc actctgaccg cgtggatcag ctcggccggc
    18481 tcggtgtcct tgaccaggaa cccgctcgcg cccgcccgca gcgcgccgta gacgtagtcg
    18541 tcgaggtcga acgtggtcag gatgatcacc ttgacgccgt cgagccgcgg gtcggtgacg
    18601 atcacgcggg tcgcctccag gccgtccagc tcgggcatcc ggatgtccat cagcaccacg
    18661 tcgggccgca actcgcgggt cctggccacg gcctcggcgc cgttggccgc ctcgccgacc
    18721 acctcgatgc cgtcctcgtc gctcaggatg gaccggaacc cggcccgtac gaggttctgg
    18781 tcgtcggcga gcactgtgcg gatcatcgca ctccgttcag tggaaggtcg gcgacgacca
    18841 ggaagccgcc gtcagggcgg ggacccgcct ccagggtgcc gcccagcgcg ccggcgcgct
    18901 cgcgcatgcc ctgcagcccg aacccgctcc cgtcggtgaa cgtcgctccc ggcccatcat
    18961 cctccacgcg gatcacgata tgtccggact ggttggtgac gctcagccga gcctcggcgg
    19021 ctcccgagtg ccgggagacg ttcgtcaggg cctccctgat gatgcgggtc gcggccaggt
    19081 ccacctcggt cggcactccg tccagccgcc cggacagctc ggtccgcacg tccacccccg
    19141 tgcccgcgac cagcgcctcc atccgggcca ggctgtcggc gggcgcggtc ggcgcgccct
    19201 cgtccacctg ccgcagcacc ccgagcgtgg tacgcagctc gcgcagcgtc tccttgctgg
    19261 tctccttgat cgtccgcagc gcggcctccg cgtcctgcgg ccgcttcttc agcccgtgca
    19321 gcgccgccgc ggcctgcacg ttgatcatcg agatgttgtg cccgagtacg tcgtgcagct
    19381 ccctggcgat gcgcagccgt tcctcgctcg cccgcagcct ggcctcctcc tccttgctgt
    19441 gcagggcgtc gagcacgcgc cgctcggcct cccgcaggta ggcgcggcgg ttgcgggtga
    19501 cgcccccacc ggcgacggcg gccaccaccc aaccggcgat catcaagaac acgctgtcgt
    19561 ccatgtgcct gatcccgccg gtctcgccca gccccatggc cagcagcgcg gccgcgcccg
    19621 cggcgatggc ggcaatcagg tggcccagct cggcggcggt gtacaggacc acgaacgcca
    19681 ggatgatgac cggcccgtcg agccgggcga aggggtagta gagcgcgacg gccaccagca
    19741 cgacgatcag tgccgcgacc gggtagcgct gccgcgccag caccccggca ccggccgcga
    19801 gcggcagcag cacgtccagc gcgttcggta cgtgacccgg ctggaggaag gacgtgacga
    19861 ccgtgcccgc cagcacggcg acgaccaccg cgagcgacac gatggtgccg gccgacaacg
    19921 tgcgcatgcc gcccattctg tacggcccgc cgtccgggtg gccaaccgcc ccgcaatggg
    19981 tagagccgga gcatgagcgt agaagacgag ttgcgtcagg tcgaagagga tctgaccagg
    20041 ttgcgagccc agaccaagga tctgcgcgac cagatcggtg acatgggcgc caccgaccag
    20101 gtggaggtag gcgcgatgat cagcatggcc gacgagcagg aagagctgat cgcggacctg
    20161 gaacgtcgcc gcgacgacct cctccggcgt cgcgacggcg gctgatccgc ggggctgctc
    20221 agcgcagggg cgcgcctacc tcgtgcaggt gccgcagcgc ctggccgtag gaggcgatca
    20281 gcccggtctc caggtagctg acacccagat cggcgcagta ctgacggacg atcggctggg
    20341 ccttgcgcag gttcggggac ggcatgttgg ggaacaggtg gtgctcgatc tggtagttga
    20401 gctggccgag cgccacgtcc acgaacacgc cgcccttgac gttgcgcgag gtcagcacct
    20461 gcttgcggag gtagtcgagc ttgtcgtcct tggtgaggat cggcatgccc ttgtggttcg
    20521 gcgcgaacgt gctgcccaga tagacgccga acagcccctg gtgcaccacc aggaagacca
    20581 gggccatgcc gatcggcagc acggtgaaga tcacgccgaa gtagcagacg aagtgcgcca
    20641 gcagcagcgc cccctcccac ttccggtgct tcgtcgtcgg ctggaacacc gccttgacac
    20701 tggcgatgtg caggtgccac gcctccagcg tgagcagggg gaagaaccag aacgcctgcc
    20761 acttggcgat gaacctcggc aggccccggc tccggcgcac ctgatcggtc gaccagacga
    20821 tcacggcggg cgagacgtcc gggtcctcgt cctcgtggtt ggggttggcg tggtggcggt
    20881 tgtgcttggt gttccaccag ccccagccca gcccgatgcc gaagtcgccg atgagcagcc
    20941 cgaggatgtc acttgcccgc cgggtcctga agacctgccg gtgccccagg tcgtgggcga
    21001 cgaatccgat ctgcgcggag gccacgccga gcgcgacggc caccagcagt tgccaccatg
    21061 agtcgccgac ccaccagaac agcgcccata gaccgacata agcggccaac accagggtca
    21121 gccgcacggc gtagtagatc ggacgccggt cgagcaggcc ggcgtcctgg atttgtcggg
    21181 ctagcttcgc gaagtcacta cctcgggttt cgagcgtgcc tgtatcggcc acaggtctcc
    21241 tcacttagag gtggaagttg cccccaccct gcgcattctc cgtgatgacg ggagatcacg
    21301 gctagtctcc gccgccgcgc ctgctcttag gctgcccagt atcgtctatg tcaagacatg
    21361 ctgcggcccc atggcctctt tgacctggtg gcagcggctg acagagatct ggcagcggcc
    21421 gcgcgcatcg tggtcggcat gacacacgta ctcatcgtcg gctccgggcc gacaggactg
    21481 accctggcca tcgagctcgc ccgccgcggc gtggaccggc gcatcgtcga gaggtcggcc
    21541 gagcccccca cgggagtgcg cggcaaaggg ctgcagcccc gcacgctgga ggtcttcgac
    21601 gacctcggcg tcatcgacga gatcctcgcc accgggagcg gctacccggg catcaggagc
    21661 tacaagggcg accagatcgt ctgggaaggc cggatggacg agcccaagga gccgtcgccg
    21721 ggcatcccgt acccgaacct gatcatgcag ccgcagtggc gcaccgagcg gatcctgcgc
    21781 gaccggctcg cggagctggg ccatcgggtc gagttcggca gcgaggtgac cggcttcgag
    21841 caggacgagc aaggcgtgac cgccacgctc agtggcggcg agaccgtccg ctgcgcttac
    21901 ctcgtcggcg ccgacggtgg ccgcagcacc attcgcaagc agcttggcgt cggcttcgcg
    21961 ggggagacgt acgagagtga gcgcatgctg ctggccgacg tcaagaccgg cgacctggac
    22021 cgcgacttct ggcacatctg gggctccatg gaggagcagg tcatgtactt cggcctctgc
    22081 ccgctgccgc acaccgacgt cttccagctc gtcgcgccgt acacgggcga ggacgacctg
    22141 cgcgcgctcg tcgccaggca cgccccgcac gtccacctcg acgagatcct gtggcgctcg
    22201 gactaccggg ccaacgtccg gatggccgag cggttccgcg tgggccgggt gttcctggcc
    22261 ggggacgccg cgcacgtgca ctcgcccgcc ggtggccagg ggctcaacac cggggtccag
    22321 gacgcctaca acctgggctg gaagctcgcc atcggctcgg cggcgctgat cgacacctac
    22381 gaggacgagc ggatggcggt ggccgcgcac gtgctgggtc tcagcacccg gctgcaccgg
    22441 gagcgcgaca tcgagcgcgg cgacaacacc aaccagctcg acctggccta cctcggcagc
    22501 gccctctcca tgggcgagcg gggcggcgag cgtctgggga cgctcttcgc cgagcagcgc
    22561 ggcacgcact tcctgctgct cggcgccacg ggccgggagt acggcgacgc gatcagggtc
    22621 ctgccgccgc tggacgggca ggaaggcgtc atcctggtcc gccccgacgg ctacatcggc
    22681 tatcacgggg acgagagcgg gctcagcgcg tacctctccg ggttcggcat cgacgcgccc
    22741 ctgaccaggg cctcctcata gcgctcctcg cccagtgccg cccggcaccg cccggccagc
    22801 gcgaccacga acggatcggc cgactcggtg atcccgcgga gcagcctggc cgcccccagc
    22861 agctcggcgg ccgtcagagg ctcgcggtgc tcggccacgc cttcgagcac ggtcgcgcgg
    22921 gcggtcctgt cctcgcaggt gaccatgagc tccaacgccc tgcgcaacgg ctcggccggc
    22981 tcggccacgc gggccagctc gacgttcatg aacgccctga actggggagg agcgtcgatg
    23041 ttcatcgcca gggcgctgcg cagcagccgg gccgcctcgc cccgatcgcc ggagcgcctg
    23101 gccagctcgg ctctggcgtg cgtcacccgg gcgatggtca gcgggtcttc ggagcgcaac
    23161 gccgcctgcc aggcccgctc cagggcggtg gcggcgccgg cgtggtcgcc cgagcgcatc
    23221 atgagctggc cgagccgcag caggaacatc atcggcccga gcggcgcccc cagcgcggcg
    23281 agctccgccg cgatcggctc cggctccttg gccaggacca gcgcgcgggc gaagtcaccg
    23341 cggttctcgg cggccagcga cagccagaag taggcggtcc actgtcccca gcggtcgccg
    23401 gtccggcgca ggccgtcgag cgccggctcc agcagggact cggcgcccgc gaccgccccg
    23461 tactcgaacc gcacgatgcc cgccaccagc agcgccgtcg acctggtcca ggtgtcggga
    23521 tgatcgcgca gccgcgcggc gcccgcctcc gtgatggcca ccacgtcgcg gggcgggccc
    23581 agcgcgacga ccatcgccca cgagtgcagc gccgccggat ggtccgactc caggaccgcc
    23641 cgggtcggct cggcacccat ggcggccatc atgcagagcc cgtgggccag ctcccgcccc
    23701 tcgggcgcca cgtcaccgac ccggcgcagc acggcggtcg cgtgcgcggc gatctcgtgc
    23761 cgtcgcccgc gcatcatcca cggccacagc ctgggcagga tgacccggag cgggtcgtcg
    23821 gagtgccgga gcgccgcgtc cagattgccc tgctcggcgt cgagcaccgc cagccacttg
    23881 acctgctcgc ccgtccgcag gtgcggctcg gcggcctcgg ccagttcggc gtagtagcgg
    23941 gcgtgggcct gcctgacctc cgggaagtcg cccgtgacgt actgcctgat cgtctccagc
    24001 atcgtgtagc ggtcgccgga gaccgcgatc agcgacttgt cgaccagcga ggagagcagc
    24061 tccaggtcac cgccgcagat ccgggcgatc gcctcggccg tcgcgccgcc ggagaacacc
    24121 gacagcccgc gcagcagctc ccgctcctcc tccgacagca ggttccagct ccagtcgatg
    24181 accgcgcgga gcgtgcggtg cctgggctcg gaggtacggc tgccgcggaa ggccagccga
    24241 tcgccgagct gctcgaccag catggacacc gacatcgtgc gcagccgcgc ggcggccagc
    24301 tcgatggcca gcgggatgcc gtcgagctcg cggcagatcc gcgccgcctc ggccggcgcc
    24361 agcaccaggt cggggcgggc cgcggcggcc cggtcgcgga gcagctccac ggcgggctcc
    24421 tccggtaacg ggagcacggg gtgcagggac tcgccgggga tgttcagcgg ctccctgctg
    24481 gtggcgatga tccgcagccc ggccacctcg cccagcagcc actgcgccac ccgcgcggcc
    24541 tcgtcgatca ggtgctcgca gttgtccagc acgatcacgg gtgacgtgcc gcgcagcgct
    24601 ttgaccagat cggacgtctt gagcacggct tccagcgcgg cccgcacccc ggcggccggg
    24661 gccagctcga ccagccacac cccgtcgggc acgcgcagcg tcgcggcggc ctcgacggcc
    24721 agccgggtct tccccgcccc gccgggcccc acgagggtga tcagccgggc gcccgtcagc
    24781 gtccggatgc gggagacgtc gtcgttccgc ccgacgaagc tggtcagccg ggcgggcaga
    24841 ttggtccgcg gcgccggctc ctcgtcacgc agcgccgcga ggtgcgcctc gcgcagctcg
    24901 gctcccggat cgacgcccag ctcgtccgcc agctccgccc tgatccgctc gaagacctcc
    24961 agcgcctctc cccgccgccc gttcgccacc atggcccgca tcagcagcgc gtggaacggc
    25021 tcgcgcagcc ggtgctcggc gaccagctcc tccaactcgg ccacaacgtc gccgcccacg
    25081 acctcgccgc ctgcgattcc gcccccgatg acgttgccgc ccgcggcgag gtccgccgcg
    25141 atcctggtcg ccagcgccgc cagccgcagc tcctccagcc gcgcggccgg ggcctcggcg
    25201 aagggcagat cgacgccggc cagcgccggg ccgcgccaga gcgccagcgc cgcgtgcgcg
    25261 tcgcccgcgc gggccagccg ctcgaaagcc cacgcgtcca cctcatcggc cgggacgtcg
    25321 agcaggtagc cgttcggatg ggaggagatc aggccagggg cctcccggcg cgccctggac
    25381 accagcgact gcaacgcggc catcggatgc tcgggcggct cgcccggcca caggtcgtcg
    25441 atcaaccggt cggtcgtcac cacccgcccg ggatcgagcg ccagccgtac cagcagcccc
    25501 cgcacccgcg caccgccgac cgcggccccc gcaacctgga gcggccccag gatcccgatc
    25561 cgcatccacc ctccaagcct cgccccctac ggtacggcgc tgttcctgct ccgtaagatc
    25621 cgcaggagga atccgggtgt tggatcgcct catgcgcgtg ctgctcaccg gctcggccgg
    25681 gttcatcggg agtcacatcg ccgaggcggt cgaccgcctc ggccacgagg tcgtccccgc
    25741 cgacgtgcgc accggcgtgg acgtccgcga cgaggtcgcg ctcaaccggc tgctgcccgg
    25801 caccgacgcc gtcgtccacc aggccgccaa ggtcgggctc ggcgtgaacg tggccgacct
    25861 gcccggctac gcctccgtca acgtgtacgg caccgcggtg ctcctggcgg cgatggcccg
    25921 gcacggcgtc ggccggctgg tgctggcctc gtcgatggtc gtgtacggcg agggcgccta
    25981 cgactgcctg gcccacggcc gggtacgccc cggcccccgg cgctcatcgg acctggcggg
    26041 cggcctgttc gacccccgct gccccacgtg cgacgccgta ctggcccccg cggtcatcgc
    26101 cgaggacgcc ccgctcgacc cgcgcaacgc ctacgccacg accaagctgg cccaggaaca
    26161 cctgtcggcc aactgggccc gcgagaccgg cggcaccgcc gtcgcgctcc gttaccacaa
    26221 cgtctacggc ccccggatgc ccagggacac gccctacgcg ggggtcgcct cgatcttcct
    26281 gtcggccctg gtggccggcc gggcgccgcg ggtcttcgag gacggagggc agcggcggga
    26341 cttcgtacac gtccgcgacg tggcccgggc caacgtcctc gccctggacg cgggcaccgc
    26401 cggggcgctc acgccgtaca acatcgccag cggcatcccc cgcacggtcg gcgacctggc
    26461 cacggcgctg gccgaacaga ccggcggtcc ggagccggtc accaccggcg agtaccggct
    26521 gggcgacgtc cgccacatcg tcgcctctcc cgcgagggcg gcggcggagc tggggttcgc
    26581 ggcggagatc gggttcggcg acggcatcaa ggagttcgcg actctgtaag caccccgtga
    26641 acagaccgaa ggcttagccg gcctggtggg cgatctggat caggttgccg caggtgtcgt
    26701 cgagcacggc ggtggtcacc ggtcccatgt cggcgggctc ctgggtgaag cgcacgccga
    26761 ggccgcggag ccgctcgtac tcggacttca cgtcgtcgac ggcgaacgag gtgtagggga
    26821 tgccgtcggc gaccagcgcc tccttgaacg gctgcaccgc cgggtggctg ctgggttcga
    26881 gcaccagctc ggtgccgtcc gggtcctgcg gggacaccac ggtcagccac cggtcctcgc
    26941 cgagcgggac gtcgtgcttc ttcacgaacc ccagcacctc ggtgtagaag cgcagcgcct
    27001 tctcctggtc gtcaacgagc acgctcgcca ggttgatcct catgccggtt ccctcttctc
    27061 gggcttggtg agccaccgct cgatgatcgg ttcgagcggg ctggtgttga tgtagtggaa
    27121 cttgtaccgg ccctcgcgcc tggtctcgac caggccggcc gcctcgagaa cgtcgagatg
    27181 ctgcgagacc gcctgccgcg acgaaccgag cccatgcttg gtagccagcc gggcgcagat
    27241 ctcaaagagc gtctgtccgt cgcggtcggt cagctcgtcg aggatcgtcc ggcgcgtgga
    27301 atcagccaag gccttgaaga cgtcacccac acgccgcacc ataggcaagc cgatacttgc
    27361 atgtcaacta gaagatggtt gttcacgact ctgtaagagc cggccggagg cttcggctct
    27421 agcctcggag gcatgatcga tgtcgtgctg ccctgcctga acgaggccgc cgccctgcca
    27481 tgggtgctgg aacgcatgcc cgacggctac cgcccgatcg tcgtggacaa cggctccacg
    27541 gacggctcgg agcgggtggc cgccgcgtac ggggcgctgg tcgtatggga gccgctgcgc
    27601 gggttcggcg cggcctgcca caccgggctg ctggcggcca cggccgagct ggtctgcttc
    27661 atggacgccg acgcctccct ggacccgcgc caactcccgc gcgtcgtcga accggtcgcg
    27721 tcgggcgcaa gcgacctggc gctgggccgc cgcctcgctg tggg
//
