LOCUS       NZ_JAHFZZ010000008     21266 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Nonomuraea sp. NEAU-A123 Scaffold8, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZZ010000008
VERSION     NZ_JAHFZZ010000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea sp. NEAU-A123
  ORGANISM  Nonomuraea sp. NEAU-A123
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 558580)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Nonomuraea triticisoli sp. nov., a novel actinobacterium isolated
            from rhizospheric soil of wheat in Langfang, Hebei Province, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 558580)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, Changjiang Road No. 600, Xiangfang
            District, Harbin, Heilongjiang Province 150036, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603905.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 04:26:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,983
            CDSs (total)                      :: 11,901
            Genes (coding)                    :: 11,761
            CDSs (with protein)               :: 11,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 28 of 140
            Pseudo Genes (incomplete)         :: 121 of 140
            Pseudo Genes (internal stop)      :: 3 of 140
            Pseudo Genes (multiple problems)  :: 12 of 140
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:52:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 151186
            Orig. end                         :: 172452
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZZ010000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21266
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21266
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21266
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11266](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11266
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(355..1308)
                     /locus_tag="KLK06_RS25845"
                     /old_locus_tag="KLK06_25840"
     CDS             complement(355..1308)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS25845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_25840"
                     /product="hypothetical protein"
                     /protein_id="WP_214638203.1"
                     /transl_table=11
                     /translation="MRIPTRAIVAAMAALLALSTVNAAGTPVIADTDPALAALTQVVPE
                     IVEEAKTTPPTEIPEGDVQRPFAIATDPDRTLVATVSETDIGIGMPEAAGNGNQPLPGL
                     VTYAAKQPSVAYAHQRTGQIARALTIIKDSSAPTEYRFPISAPEGSMLEVEDDDGTVLI
                     YNNDFYLGEIDLPWAKDANGNAVPTSYRVEGMTLIQTVNHTGAAYPVVADPALKLQCEW
                     WKAMCRLIFSKKLTKKIYNAWFVAGVAGAIEAMKYACDKLKGKAKLICKIAYTAGGASA
                     VYKVREAANKNQCFAVRFQAPGIVWYEVRKKSCQSK"
     misc_feature    complement(1357..1370)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.03"
                     /tool="antismash"
     misc_feature    1358..1373
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     misc_feature    complement(1402..1413)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     gene            1487..1801
                     /locus_tag="KLK06_RS25850"
                     /old_locus_tag="KLK06_25845"
     CDS             1487..1801
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039716.4"
                     /locus_tag="KLK06_RS25850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25845"
                     /product="DUF6289 family protein"
                     /protein_id="WP_214638204.1"
                     /transl_table=11
                     /translation="MTNPRRFRGVFFAVTCALATLLAAVLAAALVLLPAGTASATAPVA
                     EPTVNISVPPSGGDVLLVFDYFDENDKLIGQFWRGCNQPSGGWGVRQGRLVIFTPPCGP
                     "
     gene            complement(1886..2752)
                     /locus_tag="KLK06_RS25855"
                     /old_locus_tag="KLK06_25850"
     CDS             complement(1886..2752)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545912.1"
                     /locus_tag="KLK06_RS25855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25850"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_214638205.1"
                     /transl_table=11
                     /translation="MHIVRFVSPLTSADAVGVDDGDQVTQLDGVTTVGELLRLSVAELR
                     ERCAAAAGPRHPSASVRRLAPVDGLMEVWAAGVTYRRSREARVTESERAADVYELVYDA
                     ERPELFFKSVAWKVSGDGGRIAVRADSEVDVPEPELGLVLNSAGEIAGYTVVDDVSSRT
                     IEGVNPLYLPQAKIYLGACAVGPAIRPVWEVADPYALDITLTIARAGETVWDGKASTSE
                     LHRRLDDLAGYLFRADAFPDGAVLSTGTSLVPDLPFTLHDGDTVTIGIAEIGTLTSGVV
                     KGLAAMR"
     misc_feature    complement(2799..2813)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.33"
                     /tool="antismash"
     gene            2860..3561
                     /locus_tag="KLK06_RS62440"
                     /old_locus_tag="KLK06_25855"
     CDS             2860..3561
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.5"
                     /locus_tag="KLK06_RS62440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25855"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_214638206.1"
                     /transl_table=11
                     /translation="MATDPYPDTARHAHVVHALGARIVDGSLVPGTPIPIEEQLVNELG
                     VGRSAVREGVKVLAGKGLLETRRSAGTRVRPRESWNLLDADVLSWRFVPDAAPADIRVL
                     ADLRVALEPGAARVAAERADAAAIQRIDEALAALHATADDPDPFIGADLAFHRAVFGAA
                     DNDLLLYIYDMISIALRSVRQVHTRSVAHNKETLPNHERVAVAIRRRHHRKAEEAMREV
                     VEVARADALHC"
     gene            3570..4334
                     /locus_tag="KLK06_RS25865"
                     /old_locus_tag="KLK06_25860"
     CDS             3570..4334
                     /NRPS_PKS="Domain: ECH (6-244). E-value: 6e-61. Score:
                     197.8. Matches aSDomain:
                     nrpspksdomains_KLK06_RS25865_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012596.5"
                     /locus_tag="KLK06_RS25865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25860"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_214638207.1"
                     /transl_table=11
                     /translation="MDVLLDVDGPVAVITLNRPAKLNAITPEMAGALRACLDRVDTDPG
                     IRVAVLTGAGERSFCVGSDIRELDAYATPWEFRNRGDYGDAVRALRKPIIAAVNGYAYG
                     GGLELAMACDIRLAASTATFAAPEIKLGWIGGSGQSALLAHAVGPGNAAVMLLTGDPID
                     AARARDWGLVTEVLPPDKLLPAVRELAGKIAARPPIAAQTAKANLKAAYTMPLDQAIQY
                     ERDLQTVCFATADAAEGRAAFAARREPVFKGR"
     aSDomain        3588..4301
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS25865_ECH.1"
                     /evalue="6.00E-61"
                     /label="KLK06_RS25865_ECH.1"
                     /locus_tag="KLK06_RS25865"
                     /protein_end="244"
                     /protein_start="6"
                     /score="197.8"
                     /tool="antismash"
                     /translation="VDGPVAVITLNRPAKLNAITPEMAGALRACLDRVDTDPGIRVAVL
                     TGAGERSFCVGSDIRELDAYATPWEFRNRGDYGDAVRALRKPIIAAVNGYAYGGGLELA
                     MACDIRLAASTATFAAPEIKLGWIGGSGQSALLAHAVGPGNAAVMLLTGDPIDAARARD
                     WGLVTEVLPPDKLLPAVRELAGKIAARPPIAAQTAKANLKAAYTMPLDQAIQYERDLQT
                     VCFATADAAEGRAAFA"
     gene            4334..5512
                     /locus_tag="KLK06_RS25870"
                     /old_locus_tag="KLK06_25865"
     CDS             4334..5512
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014564.5"
                     /locus_tag="KLK06_RS25870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25865"
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_214638208.1"
                     /transl_table=11
                     /translation="MGVLDGYRVVDLSIAMAGPLAAMRLGDLGADVIKVEPVTGEWQRH
                     APAGGATGNRVNASFLSLNRNKRSLAVNLKSDEGRDIVHRLAATADVFLQNYRPGVAER
                     LGMDHDTISGLNPRVVYVSMSGYGETGPYVSRPGQDLLLQAMSGAMLSTGRDGDPPAPA
                     GTYAIDAITAYSAFEGTLAALLHRERTGEAQRVSVNMLDAAIAVQMQELSVFTVGGVPQ
                     RRGREPHGHTYIRAPYGVFATKDGYLALGMPRLDGLALALDLPELAGMDGHTQRDEITS
                     TVARRLPERTTAEWLEICARHDLWAGPVYGYAELVADPQVRHNGSFVTYDHRTEGTVTT
                     PGFPYGFSATPPKVRRGAPLVGEHTAEILGELGYPAERTAELVEKGVLACED"
     gene            5500..6537
                     /locus_tag="KLK06_RS25875"
                     /old_locus_tag="KLK06_25870"
     CDS             5500..6537
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_25870"
                     /product="hypothetical protein"
                     /protein_id="WP_214638209.1"
                     /transl_table=11
                     /translation="MRGLTWDHPRGHAPLDELTRLDLAGPNPYGDVPEPIEWDRQPLEG
                     FESEPIAALCESYDVLVIDHPGLGAALDSLVPMDELFSAAELARFRSGTVGRSYDSYHL
                     DGRQWALPLDAAAQVAAAWPGVHVPETWPETVEFARSGGRLALCLGGPHAFLMFCAVCS
                     GDFLDRQEGLRALELMAELLALADPEVSLRNPIGVLDAMAAGGPDLCPLVYGYATYPLA
                     FADAPAWPGRTPGSVLGGTGLAVSKSRVGGLKNAIQTHLRRLLSEPVQAGLFPAAGGQP
                     AARSVWDTAGFYRDTRDTVEAAWIRPRFPGYIAKQQRTSALIRDGLTAGRPSRDILDDL
                     HKEWT"
     gene            6534..7238
                     /locus_tag="KLK06_RS25880"
                     /old_locus_tag="KLK06_25875"
     CDS             6534..7238
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="KLK06_RS25880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25875"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_214638210.1"
                     /transl_table=11
                     /translation="MTTALVTGAAGALGRAIVGRLTADGHQVAALDLDAGSLDGTLNLA
                     ADLRDPAAIEDAFARTADRLGPVGVLVNNAAIYPSRPFLEVPLAEYDDVHAVNQRAYWL
                     AAQHAARQMTSLGGGAIINIASITMHGGWPDLAAYVATKGAATALTRALARELGPREIR
                     VNCVSPGAFPTAAEEIHPDPEAYNRFVLERQALQRRGRPEELAAVVSFLAGPDASFVTG
                     QTIEVNGGWVMA"
     gene            7235..8281
                     /locus_tag="KLK06_RS25885"
                     /old_locus_tag="KLK06_25880"
     CDS             7235..8281
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025839.5"
                     /locus_tag="KLK06_RS25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25880"
                     /product="aldose 1-epimerase family protein"
                     /protein_id="WP_214638211.1"
                     /transl_table=11
                     /translation="MTPTRRQLAELTGDPAAAGGVRLVTLGDGAERGIRTLEFRTGSGL
                     AFDVLVDRCMDIGAAEHAGRSFGWRSPTGFRHPGLHENADEDGLSWLRSFSGLIVTAGL
                     DHTLFGGEVPADTYRYPPRTSVRHGLHGRAGNLPARLTGYGERWDGDRCVLWAEGEVRQ
                     TAIFAENLRLTRRIEADLGGDEIRLTDTVTNAGFEPTPHMFLYHINLGWPLLDEGARFE
                     ADIRETLWQTDSVAEQGADHLTFPGPVPGFVEQVYEHALNPDAQGLHRVAVVNDRLGMK
                     VSVEWRDSQFPCFFEWLNLRSGNYAVGLEPSTHHVGGDAAAREDGSMIWLGPQESRTYQ
                     TTFRVETL"
     misc_feature    8487..8501
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     misc_feature    complement(8513..8524)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            8578..9972
                     /locus_tag="KLK06_RS25890"
                     /old_locus_tag="KLK06_25885"
     CDS             8578..9972
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017595267.1"
                     /locus_tag="KLK06_RS25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25885"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_214638212.1"
                     /transl_table=11
                     /translation="MSTEQGEKPLSLGTRAARNLATTTKTRPQMQAITSRWLLRMLPWV
                     DVAGGTYRVNRRLTHAVGRGRVGVVQDGADDVWIIPETLAELPALRGFDDLDVLSAIAS
                     TFTTRHFQAGEVIVAAGAPVVETFVIAHGRLNRLSTGQYGGTVTLGVIADGDQFGDEVF
                     AQDDPRWPYSVRADTAGTVMVSPRQELQRLIDGSPALREHLQRYLEGTRKPVNKRGEAA
                     VEVAAGHVGEPHLGGTFVDYELHPREYELSVSQTILRVHTRVADLYNEPMNQFEEQLRL
                     TIHEIRERQEWEMLNNREFGLLHNADYGQRINTWSGPPTPDDLDDLISMRRKTRLLLAH
                     PKAIAAFFRECNKRGLTVGSANVNGHEIPAWRGIPIFPCGKIPITDGHTSSIVAMRTGE
                     EDQGVVGLHQVGIPEEYEPGLNVRFMETSSQAVMSYLVSAYYSTAILVSDAIGILENVN
                     IAAPRS"
     gene            10001..11266
                     /locus_tag="KLK06_RS25895"
                     /old_locus_tag="KLK06_25890"
     CDS             10001..11266
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077431.1"
                     /locus_tag="KLK06_RS25895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25890"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_214638213.1"
                     /sec_met_domain="T1TS (E-value: 5e-52, bitscore: 172.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADDTPAPPAAITLPTGPSVRRAATTQVQAVPEEPDALARMPAG
                     PTGLGTSALRVPLSDLRPAARPCEHDGHEPPLPHPTLPGAVRKHSLAPLAYQEREWGDG
                     SYPPLYCPDTVRIDEDLADEVNRRLVAWAERVGIHEGRMKEFGDTGYGRLAMLTHPDTD
                     DPDMLLVAAQMNAAWWAADDYYADETALGATPTELPPRLALVTSAMDPPPPAGDYTCQL
                     EDAIQADPVLVSLRSSITHISRHATPSQVGRVCNITSQMYVSWAAYAAWRYLETPPPVW
                     RYLAARQHDSFYTSMTLIDIVGGYHLPADLFFERRFHTALMQAGTASVLVNDLYSVEKE
                     AADELPDSNVILLIAAEEKCSIREATERAVALHNDLVRGFESSRRELTAVPSAELHRFL
                     RGAQGWMAGCLEWHGSTSRYQS"
     gene            11307..12161
                     /locus_tag="KLK06_RS25900"
                     /old_locus_tag="KLK06_25895"
     CDS             11307..12161
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (86-190). E-value: 4.2e-12. Score:
                     36.7. Matches aSDomain: nrpspksdomains_KLK06_RS25900_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017570447.1"
                     /locus_tag="KLK06_RS25900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25895"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_214638214.1"
                     /transl_table=11
                     /translation="MTATQDSTVLNSLYQRSVADYWNTEKNPVNLRLGEVDGIYHHHYG
                     IGAVDWTVLDGAAETRDERVIRELHRLESAQTDLLMSWLGPLEPHHRVMDAGSGRGGSS
                     IVANLRFGCQVDGVSISESQVAFANEQARQRGVDGKVSFHFRNMLDTRFETGSFQAIWN
                     NESTMYVELSLLFAEHARLLNRGGRYVCITGCYNDAYGLPSRAISQINAHYICDIHPRS
                     TYFKEMAANRLVPIGVVDLTPATIPYWELRAKSSLATGIEQPFLDAYKNGSFQYLLIAA
                     DRA"
     aSDomain        11565..11876
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS25900_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.20E-12"
                     /label="KLK06_RS25900_oMT.1"
                     /locus_tag="KLK06_RS25900"
                     /protein_end="190"
                     /protein_start="86"
                     /score="36.7"
                     /tool="antismash"
                     /translation="LEPHHRVMDAGSGRGGSSIVANLRFGCQVDGVSISESQVAFANEQ
                     ARQRGVDGKVSFHFRNMLDTRFETGSFQAIWNNESTMYVELSLLFAEHARLLNRGGRYV
                     "
     gene            12274..13281
                     /locus_tag="KLK06_RS25905"
                     /old_locus_tag="KLK06_25900"
     CDS             12274..13281
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.5"
                     /locus_tag="KLK06_RS25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25900"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_214638215.1"
                     /transl_table=11
                     /translation="MVTRNDVARLAGTSPAVVSYVMNNGPKPVSAATKSRVLAAVEELG
                     YRPNAVARSLRARRTWTIGVIASDSAGGKSPFFGEFTRSCEDVAWERGYSVLLGNSAEQ
                     PVRAEGYVRSFLERQVDGLVLMRVRPSAQQVKELEGRVPVVTIDHEAPPFFSRLAVDDE
                     EGGYLAAAHLAGHGHTRLAFVGGPLNITAVELRLAGWRKGLAEKGLDSSLVAHAGISLE
                     GGYSAATELLAERPTALFATTDHQAIGAMRAAADLGLRVPADLAIIGFDGARESAFTVP
                     GLTTIRQPIDEMARFAAETLIAAIEQGETEPVTRIFPAELVRRGSCGCQDPRTP"
     gene            complement(13278..14147)
                     /locus_tag="KLK06_RS25910"
                     /old_locus_tag="KLK06_25905"
     CDS             complement(13278..14147)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013335.5"
                     /locus_tag="KLK06_RS25910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25905"
                     /product="nucleoside hydrolase"
                     /protein_id="WP_214638216.1"
                     /transl_table=11
                     /translation="MADRQIILDTDLGSDVDDALALAVLLGSPEVDLLGCVTVYGDTAL
                     RARLAKRLVRLAGRTLTVVPGAEKTLTDREVWWAGHEGKLFADLDTEQVSHEPDATTYL
                     TERVRRAPGEIDVVAIGPLTNIANAIQADPSFAANVRHLWIMGGRFDSPEPEHNLKCDP
                     EAAKIVFDSGAPITVTGLEITTTVRLGAGDVARIAEAGEFGKALKAEIEQWWRFWNEEW
                     NSPHDPITVLTLLAPDLFGFTGEGHVAIDAEGGSVFTEGAGRTRITVAARADEVAAQIV
                     ARTVAGPR"
     gene            complement(14169..14954)
                     /locus_tag="KLK06_RS25915"
                     /old_locus_tag="KLK06_25910"
     CDS             complement(14169..14954)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.5"
                     /locus_tag="KLK06_RS25915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25910"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_214638217.1"
                     /transl_table=11
                     /translation="MLRRTLAALVGLAFALPLLWALSSSLRGTGNLGNSLIPADPTLAN
                     YLALLTGGFGRAIANSLLVALATVLIGLAISAAAAFGLSAIRFKGQAVVFGLVVLSFLI
                     PFDAIAIPLATLFRDWNLQNTYAGLILPGLGHGLAIFLLRQFFLAIPAELVEAARIDGL
                     GWFGVFARLYLPLSRPALVSAGLTLFIFQWQAYVWPLLIGTDTAHQLGPIALANMRGQF
                     TIDYGQLFAGSVVLTVIPLAIILRFQRQFTQSIATTGLK"
     gene            complement(14957..15802)
                     /locus_tag="KLK06_RS25920"
                     /old_locus_tag="KLK06_25915"
     CDS             complement(14957..15802)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590000.1"
                     /locus_tag="KLK06_RS25920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25915"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_214638218.1"
                     /transl_table=11
                     /translation="MKVALAFLAPALVALLALRLIPAAIAVGSSLRHTSLVTGETSFVG
                     LGNYVTLFDDPTFLQSVKVTLVFSLIVNPLQIAVALALAVLYTQKFAGVRSLRSLVILP
                     IAVPPAVSAAIWSVAYRPDGMLNAVLHVLGIPQQPFLTSPQQALWCLIVLLSWIGVGYW
                     MMFLIAGMQDIPRELYEAAGIDGASAWAKFWHVTLPLLRRPLAFVLVADTVSNFLVFAP
                     VQMLTNGGPQGSTNVTMFDIFTRAYSVGDLNLAQAEVMLLVLVVLAVVIVQFRLLRAKD
                     "
     gene            complement(15799..17106)
                     /locus_tag="KLK06_RS25925"
                     /old_locus_tag="KLK06_25920"
     CDS             complement(15799..17106)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013697.5"
                     /locus_tag="KLK06_RS25925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25920"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_214638219.1"
                     /transl_table=11
                     /translation="MKFYRVIVAATLAGALAACGSGASGGSDGSSGSSGASRAADAAGP
                     IQFVGPEDPKTFAPVIAGFEAKNPGLKVTYTQVPFDQLNTVLQQRLAAKDDSIDVYTVD
                     QPRVAALATRGFLTDLTALTDKVKSAALPGQYEVNVFRDKLWALPIWTSDQFLFYNTEL
                     LEKAGVQPPSSDPAKRWTWEQTVEAGKKAQEKAGAQWAVIPEQIEQFYQLQSLAESLGG
                     GSGITGPEMLTPAITTDGWLKAMTWYHGLFANKLAPRGVGSFQTSPLFSEGKVAFFAGG
                     PWDVGTFAAAKGLKWGVAPYPYFQGGKPVTPTGSWSWGVNPASKKQTAAQKFIEYAALD
                     PEGNLQTTQNTTIIPSSKAAFEKYVPLLDAKAKGVGEIMTYDAEHTAVARPRSVGYIQF
                     EDIMTKAFADIRNGADPKARLGQATQEITTAWKQLR"
     misc_feature    complement(17125..17140)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.39"
                     /tool="antismash"
     misc_feature    17129..17144
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.95"
                     /tool="antismash"
     gene            complement(17237..17701)
                     /locus_tag="KLK06_RS25930"
                     /old_locus_tag="KLK06_25925"
     CDS             complement(17237..17701)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544898.1"
                     /locus_tag="KLK06_RS25930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25925"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_214638220.1"
                     /transl_table=11
                     /translation="MAPSVATARRVELPELLDFLRPRHHGLLSTTRADGRPQLSPVSCG
                     VDEGGRIVVSTYPDRAKTRNARRDERASICVLSDDWNGPYVQVDGRAEVLDMPEALDSL
                     VEYYRCISGEHPDWEEYRAAMRRQGKSLIRLRIDRWSPIATGGFPARLAQ"
     gene            17818..18159
                     /locus_tag="KLK06_RS25935"
                     /old_locus_tag="KLK06_25930"
     CDS             17818..18159
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017588704.1"
                     /locus_tag="KLK06_RS25935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25930"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_214638221.1"
                     /transl_table=11
                     /translation="MTTHTKSSPDASAQLLDVFKALANPVRLQVLQWLRDPDLHFPPDQ
                     AIADQHEVGVCVSHIQAKTGLAQSTVSAYMASLQRAGLVRSTRVGKWTHYRRDEERIAQ
                     LVDVLGRSL"
     misc_feature    complement(18189..18205)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(18200..18217)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            18252..19145
                     /locus_tag="KLK06_RS25940"
                     /old_locus_tag="KLK06_25935"
     CDS             18252..19145
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03620.1"
                     /locus_tag="KLK06_RS25940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25935"
                     /product="TIGR03620 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_214638222.1"
                     /transl_table=11
                     /translation="MGAIEGMDVGRFGVWTFDFEDQPASMMRESIQELEELGWPAFWIP
                     ERDGREAMTHAGFLLASTERINVINGIARIWSREPRWTQGAALLLADAYPNRHLLGLGF
                     GGGQPGAKPLQAMSDYLDEMDAATSANPLPKAPMRRLLAAYGPKMLELARDRSEGAHTY
                     HVTVGHTAQAREVLGDGPFLGVEHAVLFETDPGKAREIAREHLHVYFTTKYNIAKFLRL
                     GYTEADIDGGRGSDRLVDDLVFWGDLDTIVRKLHDHLEAGADHVGIQVLGIQPGQSAMP
                     RWRQLAEALLPQRAAE"
     gene            19178..19651
                     /locus_tag="KLK06_RS25945"
                     /old_locus_tag="KLK06_25940"
     CDS             19178..19651
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889188.1"
                     /locus_tag="KLK06_RS25945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25940"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_308168446.1"
                     /transl_table=11
                     /translation="MDIIEAPRLVLLPLAVEHADEMAVVLSDPALHTFIGGTPATVYEL
                     RNRYERLVAGPPGWRNWVIRLREDDCLVGYVQATIDGRSAEIAWVIGTPWQGRGLASEA
                     AKALVGWIVDQEIDTIVAHIHPDHAASAAVAASAGLHPTDQWQAGEMRWETRI"
     gene            19648..20130
                     /locus_tag="KLK06_RS25950"
                     /old_locus_tag="KLK06_25945"
     CDS             19648..20130
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541014.1"
                     /locus_tag="KLK06_RS25950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25945"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_214638224.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.6e-31, bitscore:
                     104.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVLSDTHAPRHWKSCPDRVAAQLRGADVILHAGDVCIGEVLA
                     ELAAYAPVHAVKGNNDGPDVDAPETLELELAGLRVAMIHDSGPAKGRWDRMRRRFPDAD
                     LVVFGHSHIPLDHHEDGLRIFNPGSPTDRRRQPHGTIGLLVIEEGHLLSSEIVPVT"
     gene            20163..20699
                     /locus_tag="KLK06_RS25955"
                     /old_locus_tag="KLK06_25950"
     CDS             20163..20699
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853301.1"
                     /locus_tag="KLK06_RS25955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25950"
                     /product="XdhC family protein"
                     /protein_id="WP_214638225.1"
                     /transl_table=11
                     /translation="MAHSHDAHSHGADALCDVAHGGAAAGGGDRTLVAVFASPVADYLL
                     RYGADLGFRVILFEPEPNRSTAPMGFEVVTAPPADLDGTADIVLTDHHRPELAAVLHEL
                     LAHKCRWIGVMGSPRHPAPYLQALAELGAREEDIARVHRPIGLNIGSRTPPEIAIATLA
                     GLLADRNGRPGGFTF"
     gene            complement(20724..20966)
                     /locus_tag="KLK06_RS25960"
                     /old_locus_tag="KLK06_25955"
     CDS             complement(20724..20966)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039716.4"
                     /locus_tag="KLK06_RS25960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_25955"
                     /product="DUF6289 family protein"
                     /protein_id="WP_214638226.1"
                     /transl_table=11
                     /translation="MIRRALLAVLLALGYLVAITTLTSAPAFARVCQLGYSCVSTYYSD
                     ETRTTVVGVRYVSCEGAGSGWGSKTIYLDFQETPC"
     misc_feature    21078..21097
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.08"
                     /tool="antismash"
     misc_feature    21118..21136
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.8"
                     /tool="antismash"
ORIGIN
        1 ggcggccgga gatggcgacc cggcggcggt gggggcggcg gccggggacc cggcggtggc
       61 gacggtggac ggggacggcg acccggcggc gagcggttcg gcagcggcgg gcgaggggag
      121 cgcggccagc gggagaagca gcagggcgag accaccggca agggcccgtg gcgtgatggc
      181 aggcatgggt gctccgggag atgtgcgcgt ggggcgaggc gagaggtgtg cgtagggcga
      241 cgcagaaggt gtgcgcgtga ggcgacgcga gaggtgtgcg ttgggcgacg cagaaggtgt
      301 gcgcgtaggg cgacgccccc gccggaccgg cgggggcgtc gggatggtgc ggcgttactt
      361 gctctggcag ctcttcttgc ggacctcgta ccagacgatg cctggcgcct ggaaccggac
      421 cgcgaagcac tggttcttgt tggcggcttc ccggaccttg tagacggccg aggcgccgcc
      481 cgccgtgtag gcgatcttgc agatcagctt ggccttgccc ttgagcttgt cgcaggcgta
      541 cttcatcgcc tcgatggcac cggcgacgcc ggccacgaac caggcgttgt agatcttctt
      601 ggtgagcttc ttcgagaaga tgagccggca catggccttc caccactcgc actgcagctt
      661 gagcgcgggg tcggcgacca cggggtaagc ggcacccgtg tggttcaccg tctggatgag
      721 cgtcatgccc tccacccggt aggaggtcgg caccgcgttg ccgttggcgt ccttggccca
      781 gggcaggtcg atctcgccga ggtagaagtc gttgttgtag atcagaacgg tgccgtcgtc
      841 gtcctcgacc tccagcatgc tgccctcggg ggcggagatc gggaatcggt actcggtcgg
      901 cgccgaggag tccttgatga tggtcagcgc ccgggcgatc tggccggtgc gctggtgggc
      961 gtaggcgacg ctgggctgct tggccgcgta ggtgaccagg ccggggagcg gctggttgcc
     1021 gttgcccgcg gcctccggca tgccgatgcc gatgtcggtc tcgctgacgg tcgcgaccag
     1081 ggtgcggtcg gggtccgtcg cgatggcgaa gggccgctgg acgtcgcctt cggggatctc
     1141 ggtgggaggc gtggtcttgg cctcttcgac gatctcgggg acgacctgag tgagtgccgc
     1201 cagagcggga tccgtgtccg cgatgaccgg ggttccggcg gcgttcacgg tgctcagagc
     1261 caggagcgcc gccatggcgg cgacgatggc ccgggtgggg atgcgcacga atgtccttcc
     1321 actatcggtg ggggcaatgc acaaacgccg caaacgtaaa gatcattatt ggccggttag
     1381 gtgatcttgg atggacgggc ggtaaacgtt tgctgtcttc cggtgtcccg tcacggaacg
     1441 cgatggaacg ccctacttat ggagaaccga cagaaaggac gcttcgatga ccaaccctcg
     1501 ccgtttccgc ggtgtcttct tcgccgtaac gtgcgcactg gccaccctcc tggccgcggt
     1561 cctcgccgcg gcactcgtgc tgctgccggc cggcaccgcg tcggccacgg cgcccgtcgc
     1621 cgagccgacg gtcaacatct cggttccccc gtccgggggc gacgtcctgc tcgtcttcga
     1681 ctacttcgac gagaacgaca agctcatcgg ccagttctgg aggggctgca accagccttc
     1741 cggaggctgg ggcgtccgtc agggaaggct cgtcatcttc acgccgccct gcggtccgtg
     1801 accacaccgg gcggcatgcg atcgggccgg gcaccagtag tggtgcccgg cccggtcctt
     1861 ttcgtgcgtt gaatccactg cccgatcagc gcatggcggc caggcccttc accacgccgc
     1921 tggtcagcgt gccgatctcg gcgatgccga tggtcacggt gtcgccgtcg tgcagcgtga
     1981 acggcaggtc ggggaccagg ctggtgccgg tggagagcac cgccccgtcg gggaaggcgt
     2041 cggcgcggaa cagatacccg gccaggtcgt ccaggcgccg gtgcagctcc gaggtggacg
     2101 ccttgccgtc ccagaccgtc tcccccgccc tggcgatggt cagcgtgatg tccagcgcgt
     2161 acgggtcggc cacctcccag acgggcctga tcgccgggcc gaccgcgcac gcccccaggt
     2221 agatcttggc ctgcggcagg tacagcgggt tgaccccctc gatggtgcgc gagctgacgt
     2281 cgtcgaccac cgtgtagccc gcgatctcgc ccgcggagtt cagcaccagg cccagctccg
     2341 gctccggcac gtcgacctcc gagtcggcgc gtacggcgat ccggccgccg tcccccgaca
     2401 ccttccaggc cacggacttg aagaacagct cgggccgctc ggcatcgtag acgagctcgt
     2461 acacgtcggc cgcccgctcg ctctcggtca cccgcgcctc gcgcgaacgc cggtaggtga
     2521 cacccgcggc ccacacctcc atcagcccgt ccacgggcgc gagcctgcgg acggacgcgg
     2581 acgggtgccg cgggccggcc gcggcggcgc accgctcgcg cagctccgcg acggacaggc
     2641 ggagcagctc gccgacggtg gtgacaccgt ccaactgcgt cacctggtcg ccgtcgtcga
     2701 cgcctacggc atccgcgctg gtcagcgggc tgacaaaacg tacgatgtgc atgaacactc
     2761 ctagcttcat cagatgaagt ccgcgcttca tctgatgaaa gtctatgaaa aagccgaccg
     2821 tcccgatact gtgccaaaca tccgaatacg gaggaaaccg tggcaaccga tccttacccg
     2881 gacacggccc ggcatgccca cgtcgtgcac gccctgggtg cccggatcgt cgacggctcg
     2941 ctggttcccg gcacgcccat cccgatcgag gagcagttgg tcaacgagct cggcgtgggc
     3001 cgttccgccg tacgggaagg cgtgaaggtg ctggccggca agggcctgct ggagaccagg
     3061 aggagcgcgg gcacccgcgt ccgtccgcgc gagtcctgga acctgctcga cgccgacgtg
     3121 ctgagctggc ggttcgtgcc cgacgcggca cccgcggaca tccgggtgct ggccgacctg
     3181 cgggtcgcgc tggagcccgg ggcggccagg gtggcggccg agcgggcgga cgcggcggcc
     3241 atccagcgca tcgacgaggc cctggccgcg ctgcacgcca cggccgacga ccccgacccc
     3301 ttcatcggcg ccgacctggc ctttcaccgg gcggtgttcg gcgccgccga caacgacctg
     3361 ctgctctaca tctacgacat gatcagcatc gccctgcgct cggtacggca ggtgcacacc
     3421 cgatcggtcg cccacaacaa ggaaacgctg cccaatcacg agcgcgtggc cgtggccatc
     3481 aggcgtcgcc atcaccgcaa ggccgaagag gccatgcgcg aggtggtcga ggtcgcccgc
     3541 gccgacgcgc tccactgctg agggaatcca tggacgtcct tctcgacgtg gacggcccgg
     3601 tggccgtcat caccctgaac agacccgcca aactcaacgc catcaccccc gagatggccg
     3661 gcgcgctgcg cgcctgcctc gaccgcgtgg acaccgaccc cggcatccgg gtggccgtgc
     3721 tcaccggcgc cggggagcgc tcgttctgcg tgggcagtga cattcgcgag ctcgacgcgt
     3781 acgccacgcc gtgggagttc cgcaatcgcg gcgactacgg cgacgcggtc cgtgccctgc
     3841 gcaagccgat catcgccgcc gtcaacggct acgcctacgg cggcggcctg gagctggcca
     3901 tggcctgcga catccggctg gccgcgagca ccgccacgtt cgccgctccc gagatcaagc
     3961 tcggctggat cggcggcagc ggccagtcgg ccctgctcgc ccacgccgtc ggccccggca
     4021 acgcggccgt catgctgctc accggcgacc cgatcgacgc cgcgcgggcc agggactggg
     4081 ggctcgtcac cgaggtgctg cccccggaca agctgttgcc ggccgtacgg gaactggccg
     4141 ggaagatcgc cgcccggccg ccgatcgcgg cccagacggc caaggccaac ctcaaggcgg
     4201 cgtacacgat gcccctcgac caggccatcc agtacgaacg cgacctgcag accgtctgct
     4261 tcgccaccgc cgacgcggcc gagggccggg ccgcgttcgc cgcgcgccgc gagcccgtct
     4321 tcaagggacg ctgatgggcg tcctcgacgg ttaccgcgtg gtcgacctgt ccatcgccat
     4381 ggcggggcca ctggccgcca tgcgtctggg cgacctgggc gcggacgtga tcaaggtgga
     4441 gccggtgacc ggcgagtggc agcgccacgc tccggccgga ggcgccacgg gcaatcgagt
     4501 caacgcctcg ttcctgtcgc tcaaccgcaa caagcgcagc ctggccgtga acctcaagtc
     4561 ggacgaaggc cgcgacatcg tccaccggct ggccgcgacg gcggacgtgt tcctgcagaa
     4621 ctaccggccc ggcgtggccg agcggctcgg catggaccac gacaccatca gcgggctcaa
     4681 tccgcgcgtc gtctacgtct ccatgtccgg gtacggcgag accggcccgt acgtgtcgag
     4741 gccgggacag gacctgctgc tccaggccat gagcggcgcc atgctcagca ccggccgcga
     4801 cggcgatccc ccggcgcccg ccggcaccta cgcgatcgac gcgatcaccg cctacagcgc
     4861 cttcgagggc acgctggccg cgctgctgca ccgcgagcgc accggcgagg cccagcgggt
     4921 gagcgtcaac atgcttgacg cggccatcgc cgtacagatg caggagctgt cggtcttcac
     4981 cgtcggcggg gtcccgcagc ggcgcgggcg cgagccacac ggccacacct acatccgcgc
     5041 gccgtacggg gtgttcgcca ccaaggacgg ttacctcgcg ctcggcatgc cccggctcga
     5101 cggactggcc ctcgcgctcg acctgcccga actggccggc atggacggcc acacccagcg
     5161 cgacgagatc acctcgacgg tcgcccggcg gctgcccgaa cgcaccaccg ccgagtggct
     5221 ggagatctgc gcccgccacg acctgtgggc cggcccggtg tacggctacg cggagctggt
     5281 cgccgacccg caggtgcggc acaacggttc gttcgtcacc tacgaccacc gcaccgaggg
     5341 cacggtcacc acgcccggct tcccgtacgg cttcagcgcc accccgccca aggtacgcag
     5401 gggcgccccg ctggtgggcg agcacaccgc ggagatactc ggcgagctcg gctacccggc
     5461 ggaacgcacg gccgagctgg tggagaaggg cgtgctggcg tgcgaggact gacctgggac
     5521 cacccccgcg gccacgcccc gctcgacgag ctcacccgcc tcgacctggc cgggccgaac
     5581 ccgtacgggg acgtgcccga gccgatcgag tgggaccgcc agccgctcga agggttcgag
     5641 tccgagccga tcgccgcgct ctgcgagtcg tacgacgtgc tggtgatcga ccaccccggg
     5701 ctgggcgcgg cgctggactc gctggtgccg atggacgagc tgttctcggc ggccgagctg
     5761 gcgcgcttcc gttcgggaac ggtcggccgc tcgtatgaca gctaccacct ggacgggcgc
     5821 cagtgggcgc tgccgctcga cgcggccgcc caggtggccg ccgcctggcc gggcgtgcat
     5881 gtcccggaga cgtggcccga gacggtggag ttcgcgcgga gcggtgggcg gctggcgctg
     5941 tgcctgggcg ggccgcacgc gttcctcatg ttctgcgcgg tgtgctcggg cgacttcctc
     6001 gaccgccaag aggggctgcg ggcgctggag ctcatggccg aactgctcgc gctggccgac
     6061 cccgaggtct cgctccgcaa cccgatcggc gtcctcgacg cgatggcggc gggcgggccg
     6121 gacctgtgcc cgctggtgta cggctacgcc acctatccgc tggccttcgc cgacgccccc
     6181 gcctggcccg gccggacacc aggaagcgtg ctcggcggca ccggcctggc ggtctccaag
     6241 agccgggtcg gtggactcaa gaacgctatc caaacccacc tgcgccggct gctgtcggag
     6301 ccggtgcagg ccgggttgtt ccccgccgcc ggaggccagc ccgccgcccg ctcggtctgg
     6361 gacaccgcgg gcttctaccg cgacacccgc gacaccgtgg aggcggcctg gatccggccg
     6421 cgcttccccg ggtacatcgc caagcagcag cggacctccg ccctgatccg cgacggactg
     6481 accgccggca ggccgtcccg cgacatcctc gacgacctgc acaaggagtg gacatgacca
     6541 cggcgctggt aaccggcgcg gccggcgcac tcggccgggc catcgtcggc cgcctgaccg
     6601 ccgacggcca ccaggtggcg gcgctcgacc tcgacgccgg ctcactcgac ggcaccctca
     6661 acctggccgc cgacctgcgc gacccggccg ccatcgagga cgccttcgcc cgtacggccg
     6721 accggctcgg cccggtcggc gtcctggtca acaacgcggc catctatccc agcaggccct
     6781 tcctggaggt gccgctggcc gagtacgacg acgtgcacgc ggtcaaccag cgcgcctact
     6841 ggctggcggc ccagcacgcg gccaggcaga tgacctcgct gggcggaggc gcgatcatca
     6901 acatcgcgtc gatcaccatg cacggcggct ggcccgacct ggccgcctac gtcgccacca
     6961 agggcgccgc caccgccctg accagggccc tggcccgcga gctcggcccg cgcgagatcc
     7021 gcgtcaactg cgtctcgccc ggcgccttcc ccacggccgc cgaggagatc caccccgatc
     7081 ccgaggcgta caaccggttc gtcctggaac ggcaggcgct ccagcggcgc ggccgcccgg
     7141 aggaactggc cgccgtggtg tcctttctcg ccggaccgga cgcgtcgttc gtcaccggcc
     7201 agaccatcga agtcaacgga gggtgggtga tggcatgacg ccgacccgca ggcaactggc
     7261 ggaactcacc ggcgacccgg ccgcggcggg cggggtccgc ctggtgacgc tcggcgacgg
     7321 cgccgagcgc ggcatccgga cgctggagtt ccgcaccggt tcaggactgg ccttcgacgt
     7381 gctggtcgac cggtgcatgg acatcggggc ggccgagcac gccgggcggt ccttcggctg
     7441 gcgctccccc accgggttcc gccatccggg gctgcacgag aacgccgacg aggacggcct
     7501 gtcctggctg cgttccttct ccgggctcat cgtcacggcc ggactcgacc acaccctgtt
     7561 cggcggcgag gtgcccgccg acacctaccg ctacccgccc cgcacgtccg tccggcacgg
     7621 cctgcacggc cgggccggca acctgcccgc ccggctgacc ggctacggcg agcgctggga
     7681 cggcgaccgc tgcgtcctgt gggccgaggg agaggtacgg cagacggcga tcttcgccga
     7741 gaacctccgc ctgacccggc gcatcgaggc cgacctgggc ggcgacgaga tccggctgac
     7801 cgacaccgtg accaacgcgg ggttcgagcc gacgccgcac atgttcctgt accacatcaa
     7861 cctcggctgg cccctgctcg acgagggcgc ccggttcgag gcggacatcc gcgagaccct
     7921 ctggcagacc gacagcgtcg ccgagcaggg ggccgaccac ctgaccttcc ccggcccggt
     7981 gccgggcttc gtggagcagg tgtacgaaca cgcgctgaac cccgacgccc aaggcctgca
     8041 ccgggtcgcg gtggtcaacg accggctggg catgaaggtc agtgtggagt ggcgggattc
     8101 gcagttcccc tgcttcttcg aatggctgaa cctgcgctcc ggcaactacg cggtcggcct
     8161 ggagccgtcc acccaccacg tgggcggcga cgcggcggcc cgggaggacg gcagcatgat
     8221 ctggctcggt ccccaggagt cgcgcacgta ccagaccact ttcagggtcg agacgctctg
     8281 atttcccaat agattggcac gtactcggat tgttgaatat agggaaataa agccggattt
     8341 gtcggtggcg caaggcggcc aacgggccat tgcctggtcg cggaacggcc tttagcatcg
     8401 aagacgtcgc gaccgaaccc caagcgtgag gcgaccgata attcgatgac gacgccgctc
     8461 acattccgcg ccaccaggac tgaggaatta tcctcgtcga tctgatttct ccggaagcga
     8521 tttcccaccc gtacgagctg acgggtttca ttccacgatc agagagtgcg aggaaacatg
     8581 tccaccgagc aaggggaaaa gccgctgagc ctgggcaccc gggccgcgcg caatctggcc
     8641 accaccacca agacccgccc gcagatgcaa gccatcacct cccgctggct gctgcgcatg
     8701 cttccctggg tggacgtggc cgggggcacc tatcgggtca accgcaggct gacccacgcg
     8761 gtgggacgcg gccgggtcgg cgtggtgcag gacggagccg acgatgtgtg gatcatcccg
     8821 gagacgctcg cggagctgcc cgcgctgcgc gggttcgacg acctggacgt gctgagcgcg
     8881 atcgcctcca cgttcacgac ccggcacttc caggccgggg aggtcatcgt cgcggccggg
     8941 gcgccggtcg tcgagacctt cgtcatcgcc cacggccggc tcaaccggct gtccaccggc
     9001 caatacggcg gcacggtgac cctcggggtc atcgcggacg gtgaccagtt cggcgacgag
     9061 gtcttcgcgc aggacgatcc ccggtggccc tactcggtca gggccgacac cgccgggacg
     9121 gtcatggtgt cgccgcggca ggagcttcag cggctgatcg acggatcgcc cgccctgcgg
     9181 gagcacctcc agcgttatct ggagggcacc cgcaagcccg tcaacaaacg cggcgaggcg
     9241 gcggtcgagg tggccgccgg gcacgtcggc gagccacacc tcggcggcac cttcgtggac
     9301 tacgagctcc atcctcgcga gtacgaactg agcgtctcgc agaccatcct gcgggtccac
     9361 acccgcgtgg cggacctcta caacgaaccg atgaaccagt tcgaggagca gctccgcctg
     9421 acgatccacg agatccgcga gcgccaggaa tgggagatgc tcaacaaccg cgagttcggg
     9481 ctgctgcaca acgcggatta cggacagcgg atcaacacct ggtcaggccc cccgaccccg
     9541 gacgacctcg atgacctgat cagcatgcgc cgcaagaccc gcctgctgct cgcacatccc
     9601 aaggcgatcg cggcgttctt ccgcgaatgc aacaagcgcg gcctgaccgt gggcagcgcc
     9661 aacgtcaacg gccacgagat cccggcctgg cgcggcatcc cgatcttccc ctgcggcaag
     9721 atcccgatca ccgacgggca caccagctcg atcgtggcca tgcgcacggg cgaggaggac
     9781 cagggggtgg tcggcctcca ccaggtcggc atccccgagg agtacgagcc cggcctgaac
     9841 gtccgcttca tggagaccag cagccaggcc gtgatgtcct acttggtcag cgcctactac
     9901 tcgacggcga tcctggtctc cgacgcgatc gggatcctgg agaacgtcaa catcgccgcc
     9961 cctcgatcct gaccgatcat catcgtagga agagggcgtc atgtccgcag acgacacccc
    10021 agcacctccc gccgccatta cgctgccgac cggcccctcc gtccgccgag ccgccaccac
    10081 ccaggtccag gccgtaccag aggagccgga cgccctggcc cggatgccgg caggtcccac
    10141 cggcctgggc acctcggcgc tgcgcgtccc gctctccgac ctacggcccg cggccaggcc
    10201 ctgtgagcat gacgggcacg aacctccgct gccgcacccg acccttccgg gcgccgtacg
    10261 caagcacagc ctcgcacccc tcgcctacca ggagcgggag tggggcgacg ggtcgtatcc
    10321 gccgctgtac tgccccgaca ccgtacgcat cgacgaggac ctggccgacg aggtcaaccg
    10381 gcggctggtg gcgtgggcgg agcgggtcgg gatccacgag ggccggatga aggagttcgg
    10441 cgacacgggc tacggccggc tggccatgct cacgcacccc gacaccgacg accccgacat
    10501 gctgctggtc gcggcgcaga tgaacgccgc ctggtgggcg gccgacgact actacgccga
    10561 cgagaccgcg ctgggcgcga caccgaccga actgccgccg cggctggccc tggtgacctc
    10621 cgccatggac ccgcccccgc ccgcgggcga ctacacctgc cagctcgagg acgcgatcca
    10681 ggccgacccc gtcctggtct cgctgaggtc gagcatcacc cacatctccc ggcacgccac
    10741 cccgtcacag gtcgggcgcg tctgcaacat cacctcccag atgtacgtga gctgggccgc
    10801 ctacgcggct tggcgctacc tggagacgcc accgccggtc tggcgctacc tcgcagcgcg
    10861 tcagcacgac agcttctaca cctccatgac gctgatcgac atcgtgggcg gttaccacct
    10921 ccccgccgac ctcttcttcg agcggcgctt ccacaccgcg ctcatgcagg caggcaccgc
    10981 cagcgtcctg gtcaacgacc tgtattccgt cgagaaggag gccgccgacg aactcccgga
    11041 ctccaacgtg atcctgctca tcgcggccga ggagaagtgt tcgatccgcg aggcgaccga
    11101 acgcgcggtc gccctccaca acgatctcgt caggggcttc gaatccagcc ggcgcgagct
    11161 caccgccgtc ccgtcagcgg aactccaccg gttcctgcgc ggagcccagg ggtggatggc
    11221 cggatgcctc gaatggcacg gctccaccag ccgctaccag tcttgacccc gctccccgcc
    11281 agttcgcgaa gaagggaatc cctcaggtga ccgctacgca ggactccacc gtcctcaaca
    11341 gcctctacca gcgatccgtc gccgactact ggaacaccga gaagaacccg gtcaacctcc
    11401 gcctgggcga agtggacggc atctaccacc atcactacgg catcggcgcc gtcgactgga
    11461 ccgtgctgga cggcgccgcg gagacccggg acgaacgcgt gatcagggag ctccatcggc
    11521 tcgaatccgc gcagaccgac ctcctcatga gctggctcgg tccgctcgaa ccccaccaca
    11581 gggtcatgga cgcgggctcg ggcagaggcg gctccagcat cgtcgccaac ctgcgcttcg
    11641 gctgtcaggt ggacggcgtg tccatttccg agtcccaggt cgccttcgcc aacgagcagg
    11701 ccaggcagcg cggcgtggac ggcaaggtca gcttccactt ccgcaacatg ctcgacaccc
    11761 gcttcgaaac tggatcgttc caggcgatct ggaacaacga gagcacgatg tacgtcgagc
    11821 tctcgctgct gttcgccgag cacgcccggc tgctgaaccg cggtggccga tacgtgtgca
    11881 tcaccggctg ctacaacgac gcctacggcc tgccgtcccg ggccatcagc cagatcaacg
    11941 cgcactacat ctgcgacatc catccgcgca gcacgtactt caaggagatg gcggccaacc
    12001 gcctcgtccc catcggcgtc gtggacctca cgcccgcgac gatcccctac tgggagctgc
    12061 gtgccaagag ctcccttgcc accggcatcg agcaaccctt cctcgacgcc tacaagaacg
    12121 gcagcttcca gtacctcctc atcgccgccg accgcgcctg acggacgtgc ccccggccgc
    12181 cgcgacgcga tcgtcgcagg cggcacccct cctgggggcg caccggtatc cgcccgtcca
    12241 acggtgctga ttcgcaggta aagtggtgag atcgtggtaa cccgtaatga cgtggcgcgc
    12301 ttggccggga cctcgcccgc cgtggtcagt tatgtgatga acaacggtcc caagccggtg
    12361 tccgcggcga ccaagagccg ggtgctggcc gccgtcgagg agctgggcta ccgtcccaac
    12421 gccgtggcca ggtctttgcg tgcgcggcgg acgtggacga tcggtgtcat cgcctctgac
    12481 agcgcgggtg gcaagagccc gttcttcggc gagttcacca ggtcgtgcga ggacgtggcc
    12541 tgggagcgcg gctactccgt cctgctcggc aactcggccg agcagcccgt acgcgccgag
    12601 ggctacgtgc ggtcgttcct ggagcggcag gtcgacgggc tggtgctgat gcgtgtacgc
    12661 ccgtcggccc agcaggtcaa ggagctggag gggcgcgtcc cggtcgtgac gatcgaccac
    12721 gaggcgccgc cgttcttctc caggctggcc gtcgacgacg aggaaggcgg ttatctcgcc
    12781 gccgcgcacc tggccgggca cgggcacacc cggctcgcgt tcgtcggcgg gccgctgaac
    12841 atcacggcgg tcgagctgcg gctggcgggc tggcgcaagg ggctggccga gaaggggctc
    12901 gacagctcac tggtcgcgca cgccgggatc agcctggagg gcggctactc ggccgccacc
    12961 gagctgctgg ccgagcgccc gacggcgctg ttcgccacca ctgaccacca ggcgatcggc
    13021 gccatgcgcg ccgccgccga cctgggcctg cgggtgcccg ccgacctggc gatcatcggg
    13081 ttcgacgggg cgcgcgagtc cgcgttcacc gtgccgggcc tgacgacgat caggcagccg
    13141 atcgacgaga tggcccgctt cgccgccgag accctgatcg ccgccatcga gcagggcgag
    13201 accgagccgg tcacccggat cttccccgcc gagctcgtcc gccgcggctc atgcggctgc
    13261 caggacccgc gcactcccta gcggggtccc gcgacggttc tggcgacgat ctgcgcggcc
    13321 acctcgtccg cacgggccgc caccgtgatc ctggtacggc ccgcgccctc ggtgaacacg
    13381 ctgccgcctt cggcgtcgat cgccacgtgg ccttccccgg tgaacccgaa caggtcgggc
    13441 gccagcagcg tcagcactgt gatcgggtcg tgcgggctgt tccactcctc gttccagaac
    13501 cgccaccact gctcgatctc cgccttcagc gccttcccga actcgcccgc ctcggcgatc
    13561 ctggccacgt cgccggcccc cagccgcacg gtcgtggtga tctccagccc ggtcacggtg
    13621 atgggggcgc cggagtcgaa cacgatcttc gcggcctcgg ggtcgcactt gaggttgtgc
    13681 tcgggctccg gggagtcgaa gcggccgccc atgatccaca ggtgccggac gttcgccgcg
    13741 aacgacgggt cggcctggat ggcgttcgcg atgttggtca gcgggccgat cgcgacgacg
    13801 tcgatctcgc ccggcgcccg gcgcacccgc tcggtgaggt aggtggtggc gtccggctca
    13861 tgggagacct gctcggtgtc gaggtcggcg aagagcttgc cctcgtggcc cgcccaccag
    13921 acctcgcggt cggtgagtgt cttctccgcg ccgggcacca cggtcagggt acggcccgcc
    13981 agccgtacca gccgcttggc cagccgcgcc cgcagcgccg tgtcaccgta gacggtgacg
    14041 cagcccagca ggtccacctc cggcgacccg agcaggacgg ccagcgcgag cgcgtcgtcc
    14101 acgtcggagc cgaggtcggt gtcgagaatg atctgacggt cagccatggt ggcctttctc
    14161 tgatgcggct acttgagccc ggtcgtcgcg atggactggg tgaactggcg ctggaagcgc
    14221 aggatgatgg ccagcgggat cacggtcagc acgaccgagc cggcgaacaa ctgcccatag
    14281 tcgatggtga actgcccgcg catgttggcc aaggcgatcg ggccgagttg atgggcggtg
    14341 tcggtgccga tgagcagcgg ccagacgtac gcctgccact ggaagatgaa cagcgtcagg
    14401 cccgcgctga cgagggcggg acgcgacagc ggcaggtaga gccgggcgaa cacgccgaac
    14461 cagcccagcc cgtcgatccg cgccgcctcc accagctcgg ccgggatggc caggaagaac
    14521 tggcgcagca ggaagatggc caggccgtgg ccgaggccgg gcaggatgag gccggcgtag
    14581 gtgttctgca ggttccagtc gcgaaacagc gtggccagcg ggatcgcgat cgcgtcgaac
    14641 gggatgagga agctcagcac gacgaggccg aagaccacgg cctggccctt gaacctgatg
    14701 gccgacaggc cgaacgccgc cgccgcggag atggccagcc cgatcaggac cgtggccagc
    14761 gcgacgagca gcgagttggc gatggcccgg ccgaagccgc ccgtgagcag cgccaggtag
    14821 ttggcgagcg tcgggtcggc ggggatcagc gagttgccga ggttgcccgt accgcgcagc
    14881 gagctgctga gcgcccagag caggggcagc gcgaaagcga ggccgacgag tgcggcgagt
    14941 gtccttctga gcatgctcag tccttggcgc gcagcaggcg gaactggacg atgaccaccg
    15001 cgagcacgac cagcaccagc agcatgacct cggcctgggc caggttgagg tcgccgacgc
    15061 tgtaggcgcg ggtgaagatg tcgaacatgg tgacgttcgt ggatccctgc gggccgccgt
    15121 tggtcagcat ctggaccggg gcgaagacca ggaagttcga caccgtgtcg gccaccagca
    15181 cgaacgccag cggcctgcgc agcagcggca gcgtcacatg ccagaatttg gcccaggcgg
    15241 aggcgccgtc gatgcccgcc gcctcataga gctcgcgcgg gatgtcctgc atgccggcga
    15301 tcaggaacat catccagtag ccgaccccga tccacgacag cagcacgatc aggcaccaca
    15361 gcgcctgctg cggcgaggtc aggaacggct gctgcgggat gccgagcacg tgcagcacgg
    15421 cgttgagcat cccgtcgggc cggtaggcca cgctccagat ggccgccgac accgcgggcg
    15481 gcaccgcgat cggcaggatc accagggagc gcagggagcg caccccggcg aacttctgcg
    15541 tgtacaggac cgccagcgcc agcgccaccg cgatctgcag cgggttcacg atcaggctga
    15601 acaccagcgt gaccttgacg ctctgcagga acgtcggatc gtcgaacagc gtcacgtagt
    15661 tgccgagccc gacgaaggac gtctcgccgg tgaccaggct ggtgtgccgc aggctgctgc
    15721 cgacggcgat ggccgcgggg atcagccgga gcgccagcag ggccaccagc gcgggcgcca
    15781 ggaaggccag cgccaccttc atcgaagctg cttccaggcg gtggtgatct cctgcgtcgc
    15841 ctggccgagc cgggccttgg ggtcggcgcc gttgcggatg tcggcgaacg ccttggtcat
    15901 gatgtcctcg aactggatgt agccgaccga cctgggccgc gccaccgccg tgtgctcggc
    15961 gtcgtacgtc atgatctcgc cgacgccctt cgccttggcg tccagcaggg gtacgtactt
    16021 ctcgaacgcc gccttgctcg acgggatgat cgtggtgttc tgcgtggtct ggaggttgcc
    16081 ttcggggtcg agcgccgcgt actcgatgaa cttctgcgcc gccgtctgct tcttggaggc
    16141 cgggttgacg ccccacgacc acgagccggt cggggtcacc ggcttaccgc cctggaagta
    16201 cgggtacggc gcgacgcccc acttcagccc cttggccgcg gcgaacgtgc ccacgtccca
    16261 cgggccgccg gcgaagaagg ccaccttgcc ctcgctgaac agcggcgagg tctggaagga
    16321 gccgacgccg cgcggggcca gcttgttcgc gaacaggccg tggtaccagg tcatcgcctt
    16381 gagccagccg tcggtcgtga tggcgggcgt cagcatctcg gggccggtga tcccggatcc
    16441 gccgccgagc gactcggcga ggctctgcaa ctggtagaac tgctcgatct gctcggggat
    16501 gaccgcccac tgggcgccgg ccttctcctg cgccttcttg ccggcctcga ccgtctgctc
    16561 ccacgtccac cgcttggccg ggtcactcga cggcggctgg acgcccgcct tctccagcag
    16621 ctcggtgttg tagaagagga actggtcgga ggtccagatg ggcagcgccc acagcttgtc
    16681 cctgaagacg ttgacctcgt actggccggg gagcgcggcg ctcttcacct tgtccgtcaa
    16741 ggcggtcagg tcggtgagga agccgcgggt ggcgagcgcg gcgacgcgcg gctggtccac
    16801 cgtgtagacg tcgatcgagt cgtccttggc cgcgaggcgc tgctggagca cggtgttgag
    16861 ctggtcgaag gggacctggg tgtacgtcac cttgagcccc gggttcttgg cctcgaaccc
    16921 ggcgatgacc ggggcgaagg tcttgggatc ctccgggccg acgaactgga tcgggcccgc
    16981 cgcgtcggcg gcccggctcg cgccgcttga tccgctcgac ccgtctgacc cgcctgacgc
    17041 gcctgacccg caggcggcca gggcgccggc cagggttgcc gcgacgatca ccctgtagaa
    17101 cttcatcccc tagctccttc tgactgaggt ctacacgtgt caccttcagt cgggccagaa
    17161 tgccatcaag cgccgcgaag aacaagcccc aggtcagacg ggccttacgt catttacccg
    17221 cgaaccggtc gtgccgctac tgcgccagcc gggcggggaa cccgccggtc gcgatcgggc
    17281 tccagcggtc gatgcgcagg cggatgaggg acttcccctg ccgccgcatg gccgcgcgat
    17341 attcctccca atcgggatgc tcgcccgaga tgcaccggta gtactccacg agcgagtcga
    17401 gcgcctcggg catgtccagc acttcggcac gtccgtcgac ctggacgtac gggccgttcc
    17461 agtcgtcgga cagcacgcag atcgacgccc gctcgtcgcg gcgggcgttg cgcgtcttgg
    17521 cccgatcggg ataggtggac accacgatcc ggccgccctc gtcgaccccg caggagaccg
    17581 gcgagagctg gggccgcccg tcggcacggg tggtcgacag cagaccgtga tgcctgggac
    17641 ggaggaaatc caggagttcg ggcagttcga cacggcgggc ggtcgcgaca ctcggagcca
    17701 tctcacgtac ctttccgcgc cgggccagcg gcggcatccg gcgtcaaggc tccgatcctt
    17761 tcacctgcca cagccccggc agacgtcggg atgaacctat actcgtctcg acggcccatg
    17821 acaacacaca ccaaatcctc accggacgcc tccgcgcagc tacttgacgt gttcaaggcg
    17881 ctggccaatc ccgtgcggct tcaggtgctc cagtggctgc gcgatcccga cctccatttc
    17941 ccgccggacc aggcgatcgc ggaccagcat gaggtcggcg tgtgcgtgag ccacattcag
    18001 gccaagaccg ggctcgcgca gtcgaccgtc tccgcctaca tggcctcgct gcagcgtgcc
    18061 gggctggtcc gctccactcg cgtggggaag tggacgcact accggcgcga cgaggaacgc
    18121 atcgcccagc tcgtcgacgt gctcggccgc tcgctctagc gttcgctacg cggtacttcg
    18181 agcctcgcat ttgttctcat atcgactttc tgcgatactt cgattcgtac cgatcgaggc
    18241 gaggaggagc catgggcgcg atcgagggca tggatgtggg gcgcttcggg gtctggacgt
    18301 tcgacttcga agaccagccg gcgagcatga tgcgagagtc catccaggag ctcgaggagc
    18361 tcggctggcc ggcgttctgg atcccggagc gggacgggcg cgaggcgatg acgcacgccg
    18421 ggttcctgct ggccagcacc gagcgcatca acgtcatcaa cggcatcgcg cggatctggt
    18481 cccgcgagcc acgatggacc cagggcgcgg cgctgctcct ggccgacgcc tatccgaatc
    18541 gccacctgct cggactcggc ttcgggggcg ggcagcccgg ggccaagccg cttcaggcga
    18601 tgagcgacta cctggacgag atggacgcgg cgacgagcgc caaccctctg ccgaaggcgc
    18661 cgatgcgacg cctgctggcc gcgtacggac cgaagatgct cgagctggcc cgcgatcggt
    18721 ccgaaggcgc tcatacctac cacgtgacgg tggggcacac cgcgcaggcg cgggaggtgc
    18781 tgggcgacgg cccgttcctc ggcgtcgagc acgcggtgct cttcgagacc gacccgggca
    18841 aggcgcgtga gatcgcccgc gagcatctgc acgtgtactt cacgacgaag tacaacatcg
    18901 ccaagttcct tcgcctgggc tacaccgaag cggacatcga cggcggccgg ggcagcgacc
    18961 ggctcgtcga cgacctggtg ttctggggcg acctcgacac gatcgtccgc aagctgcacg
    19021 accacctcga ggccggcgcc gaccacgtcg gcatccaggt gctcggcatc cagcccggcc
    19081 agtcggccat gccgcgatgg cggcagctcg ccgaggcgct gctcccccag cgagccgccg
    19141 agtaggcccg gcgaacagtc ccgatatcgt gggccacgtg gacatcatcg aggcccctcg
    19201 gctcgtcctg ctcccccttg cggtcgagca cgcggacgag atggccgtcg tgctctccga
    19261 tcccgccctg cacactttca tcggtggtac gcccgcgacc gtgtacgagc tgcgcaatcg
    19321 ctacgagcgc ctggtcgccg ggccgcccgg ctggcgcaac tgggtgatcc ggctgcgcga
    19381 ggacgactgt ctggtggggt acgtccaggc cacgatcgac ggccgcagcg ccgagatcgc
    19441 ctgggtgatc ggcaccccct ggcagggccg cggcctggcc agtgaggccg ccaaggcgct
    19501 ggtcggatgg atcgtggacc aggagatcga cacgatcgtc gcgcacatcc accccgatca
    19561 cgccgcctcg gccgccgtcg ccgcctccgc cggactgcac cccaccgacc agtggcaggc
    19621 cggcgagatg cggtgggaga cacggatatg agggcggcgg tgctgtccga cacccatgcc
    19681 ccgcggcact ggaagtcgtg cccggaccgg gtggccgccc agctgcgggg agccgatgtc
    19741 atcctgcacg cgggcgatgt ctgcatcggc gaggtgctcg ccgagctggc ggcgtacgca
    19801 ccggttcacg cggtgaaagg gaacaacgac ggaccggacg tggacgcgcc cgagacgctg
    19861 gagctggagc tcgcggggct ccgggtggcg atgatccacg acagcgggcc ggccaagggg
    19921 cgctgggacc ggatgcggcg gcgcttcccg gacgccgacc tcgtggtgtt cggtcactcg
    19981 cacatcccgc tcgaccatca cgaggacggg ctgcggatct tcaaccccgg ctcccccacc
    20041 gaccgccgcc gccaacctca cggaacgatc gggctgctcg tgatcgagga gggccacctg
    20101 ctctcgtcgg agatcgtccc cgtcacctga cggcgccgcc cgatcggggt aagactgctg
    20161 gtatggccca ttcgcatgac gcccattcgc atggcgcgga cgcgctctgt gacgtcgccc
    20221 atggcggggc ggcggccgga ggcggtgatc gcacgctcgt cgccgtgttc gcctcacctg
    20281 tcgccgacta tctgctgcgc tacggcgccg acctgggatt ccgggtgatc ctcttcgagc
    20341 cagagccgaa ccggagcacg gcgccgatgg ggttcgaggt cgtcaccgcg cccccggctg
    20401 acctggacgg caccgcggac atcgtgctca ccgaccacca ccgcccggag ctcgccgccg
    20461 tgctgcacga gctgctcgcg cacaagtgcc ggtggatagg ggtgatgggc agcccgcgcc
    20521 atccggcgcc gtatctccag gcgctggccg agctcggcgc gcgggaggag gacatcgccc
    20581 gggtgcaccg gccgatcggg ctcaacatcg gctcgcgcac gccaccggag atcgccatcg
    20641 ccaccctggc cggcctgctc gccgaccgca acggacgacc gggcggcttc accttctgaa
    20701 gccgccccgc cgcagtgcct caatcagcag ggggtctctt ggaagtcgag gtatatcgtc
    20761 ttgctgcccc agccggaacc ggcgccttca caggacacgt acctgacgcc caccaccgtg
    20821 gtgcgggttt cgtcggagta gtacgtgctg acgcagctgt atccgagctg gcagacccgg
    20881 gcgaaagcgg gagcacttgt gagggttgtg atggcgacga ggtagccgag ggcgaggagt
    20941 acggccagca gtgcgcggcg aatcatgaag atccttcccg atcgagggag cgatactgct
    21001 cccgatgatc gatcaccggc atcggaagct caatacgcgt ttgggatctt ggccgcatcc
    21061 ggccgctcac cgacaatgat gggactttcg cccctaatca tgagtagatc cgataagaga
    21121 ccctaaacag catgcaattg gactcgtccg gcctggtggt gctctcccgt gaggagtgtc
    21181 tccatctgct ggcctcgacc gcgatcgggc ggatcgtctt caccgaccgc gctctgcccg
    21241 ccgtgcaacc ggtcaacttc tgtctc
//
