LOCUS       NZ_JAHFZZ010000007     21068 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Nonomuraea sp. NEAU-A123 Scaffold7, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZZ010000007
VERSION     NZ_JAHFZZ010000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea sp. NEAU-A123
  ORGANISM  Nonomuraea sp. NEAU-A123
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 655160)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Nonomuraea triticisoli sp. nov., a novel actinobacterium isolated
            from rhizospheric soil of wheat in Langfang, Hebei Province, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 655160)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, Changjiang Road No. 600, Xiangfang
            District, Harbin, Heilongjiang Province 150036, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603905.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 04:26:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,983
            CDSs (total)                      :: 11,901
            Genes (coding)                    :: 11,761
            CDSs (with protein)               :: 11,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 28 of 140
            Pseudo Genes (incomplete)         :: 121 of 140
            Pseudo Genes (internal stop)      :: 3 of 140
            Pseudo Genes (multiple problems)  :: 12 of 140
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:52:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 318953
            Orig. end                         :: 340021
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZZ010000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            39..359
                     /locus_tag="KLK06_RS60060"
     CDS             39..359
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS60060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_250905884.1"
                     /transl_table=11
                     /translation="MSSLAFTLGTQGSAREVSLRYKDVVPTGWEPVGFGRCGVPLRTDA
                     RAAEAGLGEAGRVEVDDGVREGPSDRAGSAADAAAQEVAATKASRAATAVTPRRAVFRA
                     IT"
     gene            609..1952
                     /locus_tag="KLK06_RS62410"
                     /old_locus_tag="KLK06_23595"
     CDS             609..1952
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.5"
                     /locus_tag="KLK06_RS62410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23595"
                     /product="histidine kinase"
                     /protein_id="WP_308168407.1"
                     /transl_table=11
                     /translation="MSERRGWWQLGLDVLRPEQAPARPSRRSLLADLLLAIVLTAVAVA
                     ATASTTDGGLHRLDVRQHSLMEPLQLRPTPQPRSGEVRPDTLVRPVNPPAGDSAGSGPL
                     PLLVVLTALPLAVRRLYPLITFWVVLVAAVATSDDATWITVLTFAIAAYGAVAYSRHRA
                     LAMGGLVLATVVAGAAFQDSVPPLPSWLGPFVVLLSAGVAASFGRFWRQRLDTGRRRFA
                     ALQQAQEEAMRRAVEVERSRIAGELHDVVTHNVNVMVIQAGAARKVMDAAPAQSKQAML
                     AVEASGRAAMAELRHVMGLLAGPESARAASSADGLEPQPGLDQLDSLIKRVREAGVPVS
                     VEVSPPPGPLPPGVDLAAYRVVQEALTNTIKHAAGAAASVTIGHSGDWLEIEVTDTGGR
                     QAMRAGDGQGRGLIGLRERLALYGGTLQAGPMSGGGYQIKARVPWTST"
     gene            1937..2653
                     /locus_tag="KLK06_RS23610"
                     /old_locus_tag="KLK06_23600"
     CDS             1937..2653
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584949.1"
                     /locus_tag="KLK06_RS23610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23600"
                     /product="response regulator transcription factor"
                     /protein_id="WP_214637740.1"
                     /transl_table=11
                     /translation="MDQHVNRPLRVVIADDQALVRSGFGMILAADGIEVAAEAANGAEA
                     VAAVRRTRPDVVLMDIRMPEMDGLEATRQITANAADETRVLILTTYDLDHYVYAALTMG
                     ASAFLLKDVTPEHLVAAVRLVRAGDALLAPSITRRLVERFARRDEARAAVHRDLSELTP
                     RELEVLRLLATGLSNAELAERLSLSPTTVKTHVARILSKLGLRDRVQAVVLAYETGLIT
                     PGSPTDPPPGSARGPL"
     gene            complement(2657..2923)
                     /locus_tag="KLK06_RS23615"
                     /old_locus_tag="KLK06_23605"
     CDS             complement(2657..2923)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894160.1"
                     /locus_tag="KLK06_RS23615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23605"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_214637741.1"
                     /transl_table=11
                     /translation="MDLTAAIWRKSTRSGNNGGDCVEVAVMRGCDAGVANKAGEEFVVL
                     VRDTKNRDREPQVFTISEWDAFLDGVRGGQFDSSIMVEELHGV"
     gene            complement(2951..3895)
                     /locus_tag="KLK06_RS23620"
                     /old_locus_tag="KLK06_23610"
     CDS             complement(2951..3895)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="KLK06_RS23620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23610"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_284735094.1"
                     /transl_table=11
                     /translation="MQGPFCGFRAISLWRAGRFRLIATKDVWVARGKHIPTVASTRLAR
                     ELRTQRDNAGMSQEAVAEEMGWAESKLYRIENDKSRVLQRDVKRLLKLYGTEEKQAEVI
                     AELGRLAGEPDWWHQYSGAIPEWFQVYVVLEASASHVFGYQSELVPGILQTEGYVRSIM
                     STAPEPDSDVEIDSQVQVRVNRQARLTEKSPLNVWLVLNEAVIRRTVGGPAVMREQVEH
                     LIKIAQLRNVTLQVLPFKSGEHSAMHGSFNLLKFPAPDDPDKVYLEQQIGGIYLQKTHE
                     VERYRLMLDDLRARALGPGETIAELRAVRAELT"
     gene            3894..4352
                     /locus_tag="KLK06_RS23625"
                     /old_locus_tag="KLK06_23615"
     CDS             3894..4352
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="KLK06_RS23625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23615"
                     /product="ATP-binding protein"
                     /protein_id="WP_214637743.1"
                     /transl_table=11
                     /translation="MPYYEHEQQRSGQFLGEIVLPGVERSVSLARRCIAEILTAAGHVD
                     TDDVRLVVSELTTNAVAHTASGHPGGVVTLNIATVDAATLCIEVIDEGATTVPEVREAE
                     VGECGGRGLWLVEAFATRWGVRDGGSGQQVVWVEMSAKDGASMGTVSE"
     gene            complement(4342..5490)
                     /locus_tag="KLK06_RS23630"
                     /old_locus_tag="KLK06_23620"
     CDS             complement(4342..5490)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546588.1"
                     /locus_tag="KLK06_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23620"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_214637744.1"
                     /sec_met_domain="PCMT (E-value: 3.5e-17, bitscore: 58.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWHEHAARLAASVTSRGSRWREPVTTTPRHLFVPRWWDTPTGAS
                     FGTWQLRDGLADEQEWLATGYRDESLITQVAGVHADHATPGQVLAGRPTSSSTLPGLVV
                     RMLRHGEIYDGADVLDLATGSGYSAALLSRSLGDAHVTSIDVDLYLTEAAAERLDRVGL
                     HPKVVTCDGNGPLPGRYDRIVSMVAVRPIPASWLEALRPGGRLVTCIANTSLIVTANKT
                     DDGWARGQIERDWAMFMPTRSGSGAYGSGLADMYEAIRDQSGEDVGQGRYPVVDVGAGW
                     ELRSMLEVMAPGVEDRYEQGEDGRRTAWLLHEDGSWARASAQGMDCPTVHQAGPRRLWD
                     IFDDIRFHWLASGSLPLYGARVSITPSGVIRVWRGTWKGVIR"
     misc_feature    5480..5490
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    5900..5913
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            complement(6027..6818)
                     /locus_tag="KLK06_RS23635"
                     /old_locus_tag="KLK06_23625"
     CDS             complement(6027..6818)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853346.1"
                     /locus_tag="KLK06_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23625"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_250905886.1"
                     /transl_table=11
                     /translation="MTVGAVLLTGCGTSATQVRLAAAPAITSITTTPTAASPSATPPAG
                     AAAGPSAVAAPKKQLKLGAKGEAVMWLQNRLRELGYRPGKADGRYGGSTLTAVWAFQKV
                     NGIRPTSTIAKRTWTALENPRTPKVLVKNGRPTRAEVNLTKQIMVLYVGGQVKLITHIS
                     SGSGVPYCETATWQGKTQRFCGSASTPTGDFKTTWRAKGWHRSYLGQLYNPIFFNGGIA
                     FHGALSVPLYPASHGCVRMPMNVAVELPGLLGKGVPVHVRR"
     misc_feature    6933..6951
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            6953..7429
                     /locus_tag="KLK06_RS23640"
                     /old_locus_tag="KLK06_23630"
     CDS             6953..7429
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="KLK06_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23630"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_214637746.1"
                     /transl_table=11
                     /translation="MSEKLPANAVLVETALRALGAKGEIIVLPEKAPTAATAAAQVGCE
                     VGAIANSLIFDADGAPLLVLTSGAHRVDVELIARTAGVHKVRRATPEFVRAATGQPIGG
                     VAPVGHPAPVRTLVDNWLDKHEVVWAAGGHPLTVFPTTFDELVRITGGTAVDVE"
     gene            7440..8159
                     /locus_tag="KLK06_RS23645"
                     /old_locus_tag="KLK06_23635"
     CDS             7440..8159
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630830.1"
                     /locus_tag="KLK06_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23635"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_308168408.1"
                     /transl_table=11
                     /translation="MIEFRGAGQAEFTERLDTVIDIYIAAMRPPTDQITGRKAIMRNHG
                     TYPYFQCYFAELRGGPETPDAPSAFAEVPGEVPTLSERRRWFTASTPDTPPNSGMDAAR
                     GAAGTRHPGGATGPKIVGFAYGFRGAPGQWWHDVVFRALESRAGREAAEAWLGNAFELA
                     EIHMHPDYQGKGIGRAMITTLCAGRPERSAVLSTHDRPTMARHLYASMGFTDLLSPFLF
                     PGGYEQYAILGSRLPLT"
     misc_feature    complement(8223..8236)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    complement(8250..8263)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.08"
                     /tool="antismash"
     gene            8382..8825
                     /locus_tag="KLK06_RS23650"
                     /old_locus_tag="KLK06_23640"
     CDS             8382..8825
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891964.1"
                     /locus_tag="KLK06_RS23650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23640"
                     /product="hypothetical protein"
                     /protein_id="WP_214637747.1"
                     /transl_table=11
                     /translation="MNRTIRSLLGVTATAGLLALGVPALGAAANASTTSTAGITSATFD
                     GLRQAQPFLFTYTFNGHLKVAGGNFTVNRRVYLAVKFTTGRVAFAKWEIARPHPITPGG
                     AIYVETTIAAPCSGFKNGYARAYDEATKTWSPQLPVEICQRID"
     gene            complement(9004..9927)
                     /gene="metF"
                     /locus_tag="KLK06_RS23655"
                     /old_locus_tag="KLK06_23645"
     CDS             complement(9004..9927)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889491.1"
                     /locus_tag="KLK06_RS23655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23645"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_214637748.1"
                     /transl_table=11
                     /translation="MALGRSSILPDRVPTVRELLASGARSFSFEFFPPKTDEGERQLWR
                     AIRELESLRPTFVSVTYGAGGSSRDRTVDIVERLAHDTTLTPVAHFTAVNHSIRELRHL
                     IGRFADAGVRNILAVRGDPPGDPTGEWVQHPEGVLYAEELVRLIRQVGDFCVGVAAFPY
                     KHPRSPSIESDTDFFVRKCRAGADYAITQMFFQADDYLRLRDRVAAQGCDTPIIPCIMP
                     VTQMSTIARSEQLSGAPFPAELAARFEEVADDPAAVRRLGIDHGVELCQRLLNEGAPGI
                     HFITFNRSSATREVFERLSVVEALSA"
     gene            10001..11068
                     /locus_tag="KLK06_RS23660"
                     /old_locus_tag="KLK06_23650"
     CDS             10001..11068
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889490.1"
                     /locus_tag="KLK06_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23650"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_214637749.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-46, bitscore:
                     153.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDAASLDALRTEVDAALRKFVERQLPAPGDTELEPLRSAADDL
                     LSGGKRLRPAFCYWGWRGAGGTDVPEIFTAAASLELLQASALVHDDVMDKSDLRRGMPS
                     AHRRFEAIHEKSGWHGSAEQFGEGAAILLGNLLLIWSGEMWRSSGLPPESLAAAQPVHD
                     HMRTELMCGQYLDLLEQAHGENTFESALRVALYKSGKYSVEQPLRLGLVLAAGGLAPWM
                     DELCMEYGRRVGIAFQLRDDILGVFGDPAQTGKPAGDDLREGKRTMLVARTLAAASPGD
                     AETVRALLGDPGLDEHGVRVLRGIIEGTGALRACEDMIGDYLGEALTFLGKAPITPEAR
                     AALSSLAVAATSRTT"
     gene            complement(11104..12342)
                     /locus_tag="KLK06_RS23665"
                     /old_locus_tag="KLK06_23655"
     CDS             complement(11104..12342)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569856.1"
                     /locus_tag="KLK06_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23655"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_214637750.1"
                     /transl_table=11
                     /translation="MTTDNTGVLVCGGGPAGVMLGLLLARAGIEVTVLEKHGDFLRDFR
                     GDTVHPATVRLMDELGLGEGFRALPQSRLGNLSLPAPDGSLVTLGDFEALPAPYNYIAM
                     VPQWDLLSFLAKAAGQEPGFSLRMNTEATELVRDGEKIVGVRYRTSDGHEGEIHAELTV
                     GCDGRHSTLRREAGLVPKEFRVPFDVWWFRLPRSIRDTEAPAGVTPVAQGAEAMISLAR
                     DDYYQVAYFTAKGSDARLRAEGIQRFRERIARLRPDFAGPVEHLADMDEVFVLDVRLNR
                     LKRWYLDGLLLIGDAAHAMSPAGGVGINLAIQDAVATATILAGPLRRHAVTLADLAAVQ
                     RRRYRPTVIVQTGQRILQRVMFEKQFAGKRSGPPPFLLFLTRAFPKLRMIPARFVGFGP
                     RPEHAPDFARRTA"
     gene            complement(12339..12716)
                     /locus_tag="KLK06_RS23670"
                     /old_locus_tag="KLK06_23660"
     CDS             complement(12339..12716)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_23660"
                     /product="hypothetical protein"
                     /protein_id="WP_214637751.1"
                     /transl_table=11
                     /translation="MNLRILLTLHGLVTLAAGVVLIAAPGLVPGAVGIRIPEDAYLVCY
                     LLGAAELAVAFLSFAGRTFRQPDGVRLVAWTVIVFHGCTAAVEAYAFTGGVHAAIWANV
                     ALRLAVIALFTHYGLRQKRLT"
     gene            complement(12713..13192)
                     /locus_tag="KLK06_RS23675"
                     /old_locus_tag="KLK06_23665"
     CDS             complement(12713..13192)
                     /EC_number="2.8.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_4: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017537899.1"
                     /locus_tag="KLK06_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23665"
                     /product="sulfotransferase family protein"
                     /protein_id="WP_214637752.1"
                     /transl_table=11
                     /translation="MINVIGAGLPRTGTTSLKAALERLGFGPCHHMTVRDPHAWYASLR
                     DTVFALLHNPGAVPPEFHPVVTGMRPLLEHIWRDTFGTTLDDAMPEERHAVEVFQRHTA
                     EVTDALPADRVLIYQSGQDWQPLCDFLGVPVPDQPYPRLNDRQSAQTRLRGVADR"
     misc_feature    complement(13130..13132)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13283..14056
                     /locus_tag="KLK06_RS23680"
                     /old_locus_tag="KLK06_23670"
     CDS             13283..14056
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017624657.1"
                     /locus_tag="KLK06_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23670"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_308168409.1"
                     /transl_table=11
                     /translation="MDQDLVAAALAAAEQHGKDVADVPLSAIATAAGISRSTLIRRLRG
                     SRARLDEAVRQAGIDPGGRPPVRERAIEAAATLIARDGLGAVTMEAVAAAAHCSPTSLH
                     AVFGSRDGLLATMFDRYVPVPDLEALAADPPERIEDMVHAVYAALAEAFAREPRVLPAI
                     FGDLLTRPDGTAARMLKANLPRMFASLGTLLTTQIQAGRLRPLPLPLLIQLMIGPMAGH
                     MLLRPVLQDGLGNVLPPVEAVARTFAEAFIRATAP"
     gene            complement(14356..14991)
                     /gene="thiE"
                     /locus_tag="KLK06_RS23685"
                     /old_locus_tag="KLK06_23675"
     CDS             complement(14356..14991)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541674.1"
                     /locus_tag="KLK06_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23675"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_214637753.1"
                     /transl_table=11
                     /translation="MPKPSLSDARLYLCTDGRRERGDLADFLDAVLAAGVDIVQLREKG
                     LEAREELALLEVFRDACDRHGRLLAVNDRADIAYAARPDVLHLGQDDLPVKVAREILGD
                     DIFIGRSTHSTAEASAAAVEEGVDYFCCGPVWPTPTKPGRHAPGPSLLRHAASLGGGRP
                     WFGIGGIDLANLDQVRSYGVERVVVVRAITDADDPGAAAAEFAKRLAN"
     gene            complement(14969..15343)
                     /locus_tag="KLK06_RS23690"
                     /old_locus_tag="KLK06_23680"
     CDS             complement(14969..15343)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541673.1"
                     /locus_tag="KLK06_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23680"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_214637754.1"
                     /transl_table=11
                     /translation="MTLSVAQIDRETDQLVAEWLTLPEVAARLDLSLGRAKQLLKDRKL
                     LGVRRGGGGPQVPAVFLDGKDVMKGLPGTLSVLRDSGYDDVESLRWLFTPDDSLPGSPV
                     DAIRAGRHTEVKRRAQALAF"
     gene            complement(15374..16537)
                     /locus_tag="KLK06_RS23695"
                     /old_locus_tag="KLK06_23685"
     CDS             complement(15374..16537)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658557.1"
                     /locus_tag="KLK06_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23685"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_308168410.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.7e-48, bitscore:
                     159.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHVVVAGAGLAGVRSVEALRARGFDGRITLIGQERHRPYDRPPL
                     SKAVLTGSSDSSFVDADLAVLEVDFWPGVSAKSLRPGVVDTSEGELGFDGLVIATGAEP
                     ITLPGDGQQHVLRTLDDALELRARLVKGARVVIIGAGWIGAEVATAARRAGCEVTVIEA
                     GPTPLAQAVGPEIGARTQGWYEGIDLRLDTLVGSVDEGGITLADGAFIEAHVVVTGVGV
                     RPTVGWLAGSGIDLDNGVVADEHMRTSLPNVVAVGDCAAWWSRRFQTRLRVEHWDAALN
                     SPEVAAATLLGGDSVYDPVPYFWSEQFGHMVQYAGHHPAGDRLLYRGELEGKWSACWLN
                     SDDTLAAVLAVDRPRDLVQGRRIIEGGHRVDAECLVDPDVSLRDCVV"
     regulatory      16596..16713
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            16682..>16930
                     /locus_tag="KLK06_RS61565"
                     /old_locus_tag="KLK06_23690"
                     /pseudo=""
     CDS             16682..>16930
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.5"
                     /locus_tag="KLK06_RS61565"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23690"
                     /product="FAD-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="DAO (E-value: 3.9e-18, bitscore: 61.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAKGADVDIVVGGGIVGLSIAWRLARSGRPVTVVDPAPASGASH
                     AAAGMLAPVSEVTYTEQPLLRLGLAGLRRWPSFASELA"
     gene            17198..18256
                     /locus_tag="KLK06_RS60070"
     CDS             17198..18256
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291491.1"
                     /locus_tag="KLK06_RS60070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_308168432.1"
                     /sec_met_domain="DAO (E-value: 5.3e-32, bitscore: 106.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGVSDAARAGLDFRDDGTLAVAFGADDLAALGELAAFMEKLGLP
                     VERLTGRECRRLEPMLAPSVRGGLLARGDAWVDPRRVTTALLAALERLGVPLVRARVSE
                     LLRDGDQVVGVRLAPPDRTPTPDQDLARRTPRAHRPSGEDPVRPAPPVGEPAVAAGGLI
                     QTHVPEETRGDQITQADLPDEIRGERVILAAGAWSAGLVDVPVRPVKGQIMRLRSPQPL
                     LGRCVRGTVHGASVYLVPRGDGELVVGATQEELGFDTRVTAGGLYELLRDARELVPGVT
                     ELEVADVVAGLRPGTPDNVPLIGPSGTPGLVLATGHHRGGVLLAPLTAAILLGEEGEMA
                     ELCSPLRYRDIS"
     gene            18253..18453
                     /gene="thiS"
                     /locus_tag="KLK06_RS23715"
                     /old_locus_tag="KLK06_23705"
     CDS             18253..18453
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541670.1"
                     /locus_tag="KLK06_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23705"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_214637756.1"
                     /transl_table=11
                     /translation="MNVTINGAAHEVPDGTTVAQAILTLTAATTGVAVAVNDEVVTRSA
                     WETTALGDSDRMEVLTAVQGG"
     gene            18446..19201
                     /locus_tag="KLK06_RS23720"
                     /old_locus_tag="KLK06_23710"
     CDS             18446..19201
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541669.1"
                     /locus_tag="KLK06_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_23710"
                     /product="thiazole synthase"
                     /protein_id="WP_214637757.1"
                     /transl_table=11
                     /translation="MDDLLIAGEKFSSRLIMGTGGAPSLEVLDQALVASGTELTTVAMR
                     RLDPGAPGSVLDVLRERGIKVLPNTAGCFTAGEAVLTARLAREALGTNWVKLEVIADER
                     TLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLELAGCAAVMPLGAPIGSGLGIR
                     NPHNIELIVEAASVPVILDAGIGTASDAALAMELGCDAVLLATAVTRAQRPDLMATAMR
                     AAVQAGRLARQAGRIPRRRYAEASSPTGP"
ORIGIN
        1 tcccgccgcg ggatttcgcc gggtaccaca gggagaccat gagctccctc gccttcacgc
       61 tgggaaccca ggggtcggcg cgggaggtgt ccttgaggta caaggacgtg gtgccgaccg
      121 gctgggagcc ggtcggtttc gggaggtgcg gcgtgccgct ccggacggac gccagagcgg
      181 cggaggcggg cctgggggag gccggccggg tggaggtgga cgacggcgtc cgcgagggac
      241 cgtcggaccg ggccggctcg gctgcggacg cggcggcgca ggaggtggcg gccacgaagg
      301 cgagcagagc cgcgacggcg gtgacgcctc ggcgcgctgt cttccgagca atcacatgac
      361 ccatgaactg ttgtccttcc tgatcggatc ggccgcctcg atggaatctc cacgggcggc
      421 cgatggcagc aagcaagcta tgcgcggagg agatgggccc gcgtcggctg tcatgccgat
      481 atcgggcccc tcattgagga cgacccccag cggtgtcatc cctgcgatgt actcctgggg
      541 gacgtcaggc ccggtcaccg aggctgacgc gggacgtacc gtgcagtcgg gacaatgcat
      601 aagtgacagt gagcgaacga cgtggatggt ggcagctcgg gctggatgtg ctgcgccctg
      661 agcaggcacc cgcccggccc tcgcgccgat cccttctcgc cgacctgctg ctcgcgatcg
      721 tcctgaccgc tgtcgcggtg gccgcgacgg cgagcacgac agacggtggt ctccaccgcc
      781 tcgacgtgcg acaacactcc ctgatggagc ccttgcaact gcggccgact ccgcagccac
      841 gaagcggcga ggtccggccc gacactctgg tgcggccggt caatcccccc gccggcgact
      901 cggccggttc gggcccgctt ccgctcctgg tggtcctgac cgcgttgccg ttggcggtgc
      961 ggcggctgta tccgctgatc accttctggg tggtgctggt cgcggcggtg gccacctccg
     1021 acgacgcgac ctggatcacc gtgctgacgt tcgccatcgc cgcctatggc gccgtggcct
     1081 acagccgtca ccgggcgctg gcgatgggcg gcctcgtcct cgcgaccgtc gtggccggcg
     1141 cggccttcca ggactccgta ccgccgttgc cgagctggct gggcccgttc gtggtgctgc
     1201 tgagcgctgg ggtcgccgcg agtttcggcc ggttctggag gcagcggctc gacaccggcc
     1261 gacgccgctt cgccgcactg cagcaggctc aggaggaggc catgcgccgg gccgtcgagg
     1321 tggagcgctc ccggatcgcc ggcgaactcc acgacgtcgt cacccacaat gtgaacgtga
     1381 tggtgatcca ggccggagcg gcgcgcaagg tcatggacgc ggccccggcc cagtcgaagc
     1441 aggccatgct ggcggtcgaa gccagcggcc gggccgccat ggccgaactc cgccacgtca
     1501 tgggcctgct cgccggtccg gaaagcgcgc gggcggcgag cagcgccgac gggctcgaac
     1561 cacaaccggg actcgaccag ctcgactcct tgatcaaacg ggttcgcgaa gccggagtac
     1621 cggtcagcgt cgaggtctct ccaccgcccg gcccgctgcc gccgggggtg gacctggccg
     1681 cgtaccgcgt cgtacaggag gccttgacca acacgatcaa gcacgcggcc ggcgccgcgg
     1741 cgtccgtcac gatcggccac agcggcgact ggctggagat cgaggtcacc gacaccggcg
     1801 gccggcaggc gatgcgcgcc ggagacggcc agggcagggg cctgatcggg ctacgcgagc
     1861 ggctcgcgct ctacggcggc accctccagg cgggacccat gagcggcggc ggctaccaga
     1921 tcaaggcgag ggttccatgg accagcacgt gaaccggcca ctgcgcgtgg tcatcgccga
     1981 cgaccaggcg ctggtacgca gcgggttcgg catgatcctc gccgccgacg gcatcgaggt
     2041 ggcggccgag gcggccaacg gtgccgaagc cgtcgccgcc gtccggcgca cccgacccga
     2101 cgtcgtgctc atggacatcc ggatgccgga gatggacggc ctcgaagcca cccggcagat
     2161 cacggcgaac gccgcggacg agacccgcgt cctcatcctg accacctacg acctcgatca
     2221 ctatgtctat gccgcgctca ccatgggggc cagcgcgttc ctgctcaagg acgtcacgcc
     2281 cgagcacctg gtagccgcgg tgcgcctggt ccgcgcgggc gacgccctgc tcgccccgtc
     2341 gatcacccgc cgcctggtcg aacggttcgc ccgccgcgac gaggcccggg cggccgttca
     2401 ccgcgacctg tcggagctga caccccggga gctggaggtg ttgcgcctgc tcgccaccgg
     2461 actgagcaac gccgaactcg ccgaacgcct gagcctcagc ccgacgacgg tgaagaccca
     2521 cgtcgcgcgc atcctgtcca aactcggcct cagggaccgg gttcaggcgg tcgtgctcgc
     2581 gtacgaaacc gggttgatca ctccgggctc acccaccgac ccgccgccag ggagtgcgcg
     2641 ggggccgttg tagccatcaa acgccgtgca attcctcaac catgatcgac gaatcgaact
     2701 gcccgccccg cactccgtcc aggaaagcgt cccattccga gatcgtgaac acctgcggct
     2761 cacgatcccg attcttggtg tcacgaacga gaacgacgaa ctcctcgccg gccttgttgg
     2821 cgacccctgc gtcacagcca cgcatgacag cgacctcgac gcagtcgccg ccgttgttgc
     2881 cgctccgagt gctcttgcgc cagattgcgg cggttaggtc cacgatgggc ccttccctca
     2941 ctgccggtca tcacgtcaac tctgcccgca ctgcgcggag ctcggcgatc gtctctccag
     3001 gaccgagcgc tcgagcgcgt agatcatcga gcatcagcct gtaccgctcc acttcgtgcg
     3061 tcttctgcag gtagataccc ccgatttgtt gctctagata caccttgtcg ggatcatcgg
     3121 gcgccggaaa cttcaagagg ttgaacgagc cgtgcatggc gctgtgctca ccgctcttga
     3181 agggaaggac ttgaagggtc acgttacgga gttgggcaat cttgatcaga tgctcgacct
     3241 gttcacgcat gacagcgggc ccacctacgg tgcgccggat aacggcctcg ttcagcacaa
     3301 gccagacatt gagcgggctc ttctctgtga gtcgggcttg gcggttcact cgaacctgga
     3361 cctggctatc gatctcgacg tcggagtcag gctcgggcgc ggtggacatg atcgatcgca
     3421 cgtagccctc ggtctgcagg atcccgggaa cgagttccga ctggtagccg aagacatgtg
     3481 aggcagaagc ctccagcacc acatagacct ggaaccactc cggaatcgcc cccgagtact
     3541 gatgccacca gtcaggctcg cccgcgaggc gaccaagctc ggcgatcacc tccgcttgct
     3601 tctcctcagt cccataaagc ttgaggaggc gcttaacatc gcgctgcagg acgcggcttt
     3661 tgtcgttctc gatccgatat agcttgcttt ccgcccagcc catctcttcg gctacggcct
     3721 cttgactcat tcccgcattg tcacgctgag tccgaagctc cctggccaga cgcgtactgg
     3781 caacggtggg gatgtgcttg cctcgcgcca cccatacgtc ctttgtcgca attaggcgga
     3841 atcgtcctgc ccgccaaagg gagatagccc gaaatccgca gaaagggcct tgcatgccgt
     3901 attacgaaca cgaacagcaa cgaagcgggc agttcctggg cgagatcgtg ttgccgggag
     3961 tggagcgttc ggtgtcgctt gctcgtcggt gtatcgcgga gatcctgacg gccgcagggc
     4021 acgtggacac cgacgatgtg cggctggtgg tcagcgagct gaccacgaac gccgtggcgc
     4081 acaccgcgtc cggccaccct ggtggcgtgg tcaccttgaa catcgccacc gtcgatgccg
     4141 cgacgctctg catcgaggtg atcgacgagg gcgcgacgac ggtcccggag gtgcgagagg
     4201 ccgaggtcgg tgagtgcggc gggcgcgggt tgtggctggt cgaggcgttc gcgactcggt
     4261 ggggcgtacg agatgggggc tcggggcagc aggtggtgtg ggtggagatg tcggccaaag
     4321 acggagcttc gatggggacg gtcagcgaat aacgcccttc caggtgcccc gccatacgcg
     4381 aatgaccccg ctgggcgtga tggagacgcg agcgccgtac aacggcagtg acccgctggc
     4441 cagccaatgg aaccgaatat cgtcgaagat gtcccacaac ctgcgaggcc ccgcctgatg
     4501 cacggtcgga cagtccatcc cctgcgcact ggcccgagcc cacgacccgt cctcgtgcag
     4561 aagccaggcc gtccgacgac catcctcccc ctgttcgtac cggtcctcga cccccggggc
     4621 catgacctcc agcattgacc gcaactccca cccggctccg acgtcgacga cgggataccg
     4681 cccctgcccg acgtcctcgc cggactgatc ccggatcgcc tcgtacatgt cggcaagccc
     4741 cgacccgtac gctccgctcc cggaacgggt gggcatgaac atcgcccaat cacgctcgat
     4801 ctgcccgcgc gcccaaccgt cgtcggtctt gttcgccgta acgatcagcg aggtgttggc
     4861 gatgcaggtg accagccgcc ctccggggcg cagggcttcc agccaactcg cgggtatcgg
     4921 ccgtaccgcg accatcgaca cgatccggtc gtaccggccg ggcagcgggc cgttcccatc
     4981 gcaggtgacg accttggggt gcagaccgac gcgatcgagc cgctcggcgg cggcctcggt
     5041 cagatagagg tctacgtcga tgctggtgac gtgcgcatcg cccagcgacc gagacagcag
     5101 cgcggcactg tagcccgagc ccgtagccag gtcgagcacg tccgcgccgt cgtagatctc
     5161 cccgtgccgc agcatacgaa caaccagacc aggcagtgtg gagctggagg tcggccgccc
     5221 ggcgaggacc tgtccggggg tggcatgatc ggcgtgcacg cccgccacct gcgtgatcag
     5281 actctcgtca cggtagcccg tcgccagcca ctcctgctcg tcagcaagcc cgtcgcgtag
     5341 ttgccacgtg ccgaacgagg cgccagttgg ggtatcccac caccggggaa cgaacaggtg
     5401 gcggggagtg gtcgtgacgg gctcgcgcca ccgtgaccca cgcgaagtca cgctggcggc
     5461 gagccgagcg gcgtgttcgt gccaggtcac tgatggagtc ctcaggagtc gggatcgcag
     5521 tacgaaggat cacatacctc ggtctccgcg ggtgcgcagt ctgatccgtc tcctgtgccc
     5581 ggtttgcact cgggattgca catgttagtg aggctacggg ctgccgggat cgttgaactg
     5641 aatctgggga atgccaagcg cgacaccctg atcaatgacc gaaatccaat cgtcgttgat
     5701 catcgtgcca ggtgtccccg cgggacccga atcggcgtag cagtggacgc attgaagggc
     5761 gcacctgccg gtcagctcaa gttctagggt gcttatgatc atcccgctat gggacgtccc
     5821 cacgggatct gggtgggggt tgctcatcag cgatcgactc ctctcgaagc ggcccgtcga
     5881 tacgcacacg gtaagtgaga ccacgctccg tgacggcgct tttcgagagt tgtcgaacga
     5941 tcatctgcag cgcccaggat gccgaaaggc ccgcgaactc cgggacgaga acttcccgaa
     6001 gctcgcgggc ctgttgccgg cgaaagctag cgtcgcacgt gcaccggtac gcccttgccg
     6061 agcagtccgg gcagctcgac cgccacgttc atcggcatcc gtacgcaccc gtgagacgcc
     6121 gggtacagcg gcaccgacag cgcaccgtgg aacgcgatgc cgccgttgaa gaagatcggg
     6181 ttgtacagct ggcccaggta cgaccggtgc cagcccttcg cgcgccacgt cgtcttgaag
     6241 tcgcccgtgg gcgtgctggc cgagccgcag aagcgctggg tcttgccctg ccacgtcgcc
     6301 gtctcgcagt aggggacgcc gctgccggac gagatgtggg tgatcagctt cacctggccg
     6361 ccgacgtaca ggaccatgat ctgcttggtc aggttgacct cggcgcgggt cggccggccg
     6421 ttcttgacca ggaccttggg ggtcctgggg ttctccagcg cggtccatgt gcgcttggcg
     6481 atcgtgctgg tcggcctgat gccgttgacc ttctggaacg cccatacggc cgtcagcgtc
     6541 gatccgccgt accggccgtc tgccttgccc ggacggtaac cgagctctct gagccggttc
     6601 tgcagccaca tgaccgcttc gcccttggca cccagcttga gctgtttctt cggcgcggcg
     6661 accgcgctcg gtcccgctgc ggcgcccgcg ggaggcgtcg cactgggcga ggccgcggtc
     6721 ggtgttgtcg tgatggaagt gatggcgggc gcggcggcca gccgcacctg ggtcgcggac
     6781 gtgccgcacc ccgtcaggag tactgcacca accgtcaaga gagcagccac gccgggtagc
     6841 cgtcggtccc ccaccccgta ccacctctca taccatgaac attcgaatca aaggacccta
     6901 caccaccacc atgtccaggt aatgcaatgg tcaatctgtt tagagtgtgc ccatgtctga
     6961 gaagttgccg gctaacgccg ttctggtgga aaccgccctc cgcgcgctgg gcgccaaggg
     7021 agagatcatc gtcttgccgg aaaaagcgcc cactgcggcc accgccgccg cgcaggtcgg
     7081 ctgcgaggtc ggcgccatcg ccaacagcct catcttcgac gcggacggcg cgccgctcct
     7141 cgtgctgacc agcggtgcgc accgcgtcga cgtcgagttg atcgcccgca cggcgggggt
     7201 tcataaagta cggcgggcga cgccggagtt cgtcagggcg gcgacgggcc agccgatcgg
     7261 cggcgtcgcg cccgtggggc atccggcccc ggtgcggacc ctggtggaca actggctgga
     7321 caagcacgag gtcgtatggg cggcgggcgg gcacccgctc actgtctttc ccaccacatt
     7381 cgatgagctg gtgcggatca ccggtggtac cgccgtcgac gtcgagtagt gtgcgacgcg
     7441 tgatcgagtt tcgcggggcg ggtcaggcgg agttcaccga acgcctggac acggtgatcg
     7501 acatctatat cgccgccatg cgcccgccca cggaccagat caccggccgc aaggccatca
     7561 tgcgaaatca cggcacatat ccctatttcc agtgctactt cgctgagttg cgtgggggcc
     7621 cggagactcc ggacgcgcct tcggccttcg ccgaggttcc gggcgaggtt ccgacgctga
     7681 gcgaacgcag gcggtggttc accgcctcga cgccggacac cccaccgaac agcgggatgg
     7741 acgcagcgcg gggcgccgct ggaacgcgac accccggcgg cgcgaccggc ccgaagatcg
     7801 tcggcttcgc ctacggcttc cggggcgccc cgggccagtg gtggcacgac gtcgtgttcc
     7861 gcgcgctgga gagccgcgcg ggcagggagg ccgccgaagc ctggctgggc aacgcgttcg
     7921 aactggccga gatccacatg caccccgact accagggcaa gggcatcggc cgggccatga
     7981 tcaccacgct gtgcgcgggc cgccccgagc gttcggcggt cctgtccacg cacgaccgtc
     8041 ccaccatggc ccgccacctg tacgccagca tgggcttcac cgatctgctg agcccgttcc
     8101 tgtttcctgg cggttacgag cagtacgcga tcttgggcag ccgtctccct ctgacctgat
     8161 ccatgatcag gccgaccggc caagaacagt cgtggctgtt gccgggtcga tcgccaggcc
     8221 cggcaaccgt catgcctgcg tggccgaatt tagacaaact ccagcggtct gcatgcggac
     8281 gtcagccggc tgaaagcgca ttacaggcgg cccgcctatc aatggtgatg caagcccctc
     8341 aacgggcccg cacggttcac gccatcacct aggagatccc gatgaaccgc accatccgca
     8401 gcctgctcgg agtcaccgcc accgccggcc ttctcgccct gggcgtccca gccctcggcg
     8461 ccgccgcgaa cgcgtcgacc acatccaccg cgggcatcac cagcgcgacc ttcgacggtc
     8521 tccggcaggc ccagcccttc ctgttcactt acaccttcaa cggccatctc aaggtcgccg
     8581 gcggcaattt caccgtcaac cgccgtgtct acctggccgt caagttcacc accggccggg
     8641 tggcgttcgc caagtgggag atcgctcggc cgcaccccat cacccccggc ggggccatct
     8701 atgtggagac gacgatcgcc gctccctgct ccgggttcaa gaacggctac gctcgcgcgt
     8761 acgacgaggc caccaagacg tggtctcctc agctgccggt ggaaatctgc cagcggatcg
     8821 actgatcccc tggaacgacc ggggcagcgc gcagaccact tagacggtca acaaggcgca
     8881 cgtcacggcg gccggccggg gaacctcgta accgttcccc tggacaggcc ccagccccgg
     8941 tcggcggttg gggcccaccg ggcttagccg tacagaaaac tgcttttcat gggaaagccg
     9001 gcgtcacgcg gacagcgcct ccaccacgga cagccgctcg aacacctctc gcgtcgcgct
     9061 cgaccggttg aaggtgatga agtggatgcc cggcgcgccc tcattgagca gccgctggca
     9121 gagctccacc ccgtgatcga tccccagccg ccgcacggcc gccgggtcgt cggccacctc
     9181 ctcgaagcgg gccgccagct ccgccgggaa cggcgccccc gacaactgct ccgacctggc
     9241 gatcgtgctc atctgggtga ctggcatgat gcacgggatg atcggcgtgt cgcagccctg
     9301 cgccgccacc cggtcgcgca gccgcaggta gtcgtccgcc tggaagaaca tctgggtgat
     9361 cgcgtagtcg gccccggccc ggcacttgcg gacgaagaag tcggtgtcgg actcgatcga
     9421 cggcgagcgc gggtgtttgt acgggaacgc cgccacgccc acgcagaagt cgcccacctg
     9481 ccggatcagc cgcacgagct cctcggcgta gaggacgcct tcgggatgct ggacccactc
     9541 ccccgtcggg tcgcccggag ggtcgccccg cacggcgagg atgttgcgca cgcccgcgtc
     9601 cgcgaagcgg ccgatcaggt ggcgcagctc gcggatcgag tggttgacgg cggtgaaatg
     9661 cgccacagga gtgagcgtgg tgtcgtgggc cagccgttcg acgatgtcca ccgtgcggtc
     9721 acggctggag ccccccgcgc cgtacgtcac ggacacgaac gtcggccgca gcgactccag
     9781 ctccctgatc gcccgccaca gctgccgctc cccctcgtcg gtcttcggcg ggaagaactc
     9841 gaaggagaac gaccgtgcac cggaggcgag aagctcgcgg acggtgggga cacgatcggg
     9901 caggatggag gatcgaccaa gcgccatgtg aaccaggcta ccgccacatg ccccgtccct
     9961 ggagatccgc cttggctgcc cggccactag tctcagtgct atgaccactg acgccgcgag
    10021 cctggacgca ctgcgtaccg aggtggacgc cgcgctgcgg aagttcgtcg aacggcagct
    10081 gcccgccccc ggcgacaccg aactcgaacc gctccgctcg gccgccgacg acctgctgtc
    10141 cggcggcaag cggctgcgcc cggccttctg ctactggggc tggcgtggcg cgggcggcac
    10201 cgacgtgccc gagatcttca ccgccgccgc gtcgctggag ctcctccagg ccagcgccct
    10261 ggtgcacgac gacgtgatgg acaagagcga cctgcgcaga ggcatgccgt ccgcgcaccg
    10321 ccgcttcgag gcgatccatg agaagtcggg ctggcacggc tcggcggagc agttcggcga
    10381 gggcgcggcg atcctgctgg gcaacctgct gctgatctgg tccggcgaga tgtggcgcag
    10441 cagcggcctg ccgcccgagt cgctcgcggc ggcgcagccg gtgcacgacc acatgcgtac
    10501 cgagctgatg tgcggccaat acctcgacct gctggagcag gcgcacggcg agaacacctt
    10561 cgagtccgcc ctgcgcgtcg ccctctacaa gagcggcaaa tactccgtcg aacaaccgct
    10621 ccgcctcggc ctggtgctcg ccgccggcgg gctggcgccg tggatggacg agctctgtat
    10681 ggagtacggc cggcgcgtcg gcatcgcgtt ccagttgcgc gacgacatcc tgggcgtgtt
    10741 cggcgacccg gcgcagaccg gtaaaccggc gggcgacgac ctgcgcgagg gcaagcggac
    10801 gatgctggtc gccaggacgc tggccgcggc ctcgcccggc gacgccgaga ccgtgcgcgc
    10861 cctgctcggc gacccggggc tcgacgagca cggggtgagg gtgctgcggg gcatcatcga
    10921 gggcaccggg gcgctgcggg cgtgtgagga catgatcggc gactacctcg gcgaggcact
    10981 gacgttcctc ggcaaggcgc ccatcacgcc ggaggcccgc gcggccctgt caagcctggc
    11041 ggtggccgcc acctcacgca ccacctgagc cccggcgacc acacctcgac acgcggcttc
    11101 ctcctaggcg gtcctgcggg cgaagtcggg ggcgtgttcc gggcgggggc cgaagcccac
    11161 gaaccgggcg ggaatcatcc ggagcttggg gaaagcgcgg gtgaggaaga gcaggaacgg
    11221 gggcggcccg gaacgcttgc ccgcgaactg cttctcgaac atgacgcgct ggagtatccg
    11281 ctggccggtc tggacgatca cggtggggcg atacctgcgc cgttgcacgg ccgccaggtc
    11341 ggcaagggtg acggcgtgcc gccgcagagg gccggccagg atggtggcgg tggccacggc
    11401 atcctggatg gcgaggttga tgcccacccc gccggcgggg gacatggcgt gcgcggcgtc
    11461 gccgatgagc agcagcccgt cgagatacca gcgcttgagc cggttgagcc gcacatcgag
    11521 gacgaacacc tcgtccatgt cggccaggtg ctccaccggg ccggcgaagt cgggacgcag
    11581 gcgggcgatg cgctcgcgga accgttggat cccctcggcc cgcagccgcg cgtcggagcc
    11641 cttggcggtg aagtaggcca cctggtagta gtcgtcacgg gcgagggaga tcatggcctc
    11701 ggcaccttgc gcgaccggcg tcacgccggc gggcgcttcc gtgtcgcgaa tcgatcgagg
    11761 caggcggaac caccagacgt cgaacggcac ccggaactcc ttgggcacca gccccgcctc
    11821 ccggcgcagc gtggagtgcc tgccgtcgca ccccaccgtc agctcggcgt gaatctcccc
    11881 ttcatggccg tccgacgtgc gatatctgac cccgacgatc ttttcgccgt ctctgaccag
    11941 ctcggtcgct tcggtgttca tgcgaaggga gaacccgggc tcctgacccg ccgccttggc
    12001 gaggaaggag agcaggtccc attggggcac catcgcgatg tagttgtagg gcgcgggcag
    12061 cgcttcgaag tcgcccaggg tcaccaggct cccgtcgggg gcgggcagcg acaggttgcc
    12121 caggcggctc tgcggcagag cgcggaagcc ctcgccgagt ccgagctcgt ccatgaggcg
    12181 gacggtggcg ggatgcacgg tgtctcccct gaagtcgcgc aggaagtcgc cgtgcttctc
    12241 cagtacggtg acctcgatcc ccgcgcgggc cagcagcagg cccagcatca cgccggccgg
    12301 gcctccgccg cataccagga ctccggtgtt gtcggtggtc atgtcagcct cttctggcgc
    12361 aggccgtagt gggtgaacag agcgatgacc gccagccgca gcgccacgtt cgcccagatc
    12421 gcggcgtgga cgccgccggt gaaggcgtag gcctcgacgg cggcggtgca accgtggaac
    12481 acgatcacgg tccaggcgac caggcgcacc ccgtccggtt ggcggaaggt tctgcccgcg
    12541 aacgacagga acgccacggc cagctcggcg gctcccagca ggtagcacac cagataggcg
    12601 tcctcgggga tgcgtatgcc gacggcgccg ggaaccaggc cgggcgcggc gatgagcacc
    12661 acgcccgctg ccaaggtgac caggccgtgg agggtcagca ggatgcggag attcaccggt
    12721 ccgccacccc tcgcaggcgg gtctgggcgg actgccggtc gttgaggcgc gggtacggct
    12781 ggtccggcac gggcacgccc aggaagtcgc agagcggctg ccagtcctgc ccgctctggt
    12841 agatcaggac ccggtcggcg ggcagtgcgt cggtgacctc ggccgtgtgg cgctggaaca
    12901 cctccacggc gtggcgctcc tcgggcatcg cgtcgtccaa tgtcgtgccg aacgtgtcgc
    12961 gccagatgtg ctccagcagc ggccgcatgc cggtgaccac ggggtggaac tcgggcggca
    13021 ccgcgccggg gttgtgcagc agcgcgaaga cggtgtcgcg gaggctggcg taccaggcgt
    13081 gcgggtcacg aacggtcatg tggtgacagg ggccgaagcc gagccgctct aacgccgcct
    13141 tcagcgacgt ggtcccggta cgcggcagtc ccgcgccgat cacgttgatc atccgtgcac
    13201 ctcctaattc atcagaggat gagtctctga tggagacgat acacagataa ggttcacacc
    13261 ggaagcggta ccatgacacg tcgtggacca agacctcgtg gcggccgcgc tggcggccgc
    13321 cgagcagcac ggcaaagacg tggccgacgt gccgctgagc gccatcgcca ccgccgcggg
    13381 catctcccgc agcactctga tcagaagact ccgcggatca cgggcccggc tggacgaggc
    13441 ggtccggcag gccgggatcg atcccggcgg gcgcccgccg gtccgggaac gggccatcga
    13501 ggccgcggcc acactgatcg cccgcgacgg gctcggcgcg gtcaccatgg aggccgtcgc
    13561 ggccgccgcg cactgctcgc cgaccagcct gcacgcggtc ttcggcagcc gcgacggcct
    13621 gctcgccacc atgttcgacc ggtacgtccc cgtgcccgac ctggaggcgc tggccgccga
    13681 tccccccgaa cgcatcgagg acatggtcca cgccgtctac gccgcgctgg cggaggcgtt
    13741 cgcccgcgag ccacgggtgc tgccggccat cttcggcgac ctgctcaccc gccccgacgg
    13801 caccgccgcc cggatgctca aggccaacct gcccagaatg ttcgccagcc tcggcaccct
    13861 gctgaccaca cagatccaag ccggccggct acgacccctc ccccttccgc tcctcatcca
    13921 gctcatgatc ggccccatgg cagggcacat gctgctgcgt cctgtactac aagacgggtt
    13981 ggggaacgtc ctgcccccgg ttgaagcggt cgcgcggaca ttcgccgagg cgttcatacg
    14041 cgccaccgcc ccctgagcct ggcgccgctc caccggccac cgacgactcg gatcgtcgtg
    14101 cgcgccgcca gcccggacgg cggcgtcttc atgcgagggt gtcaggagca ggtggtggtg
    14161 gcgggctcgc tgtggaagcg gtcggcggtc caggcgacag gcggatcacg cgttgctacc
    14221 gccggcagga tgacctgaag cgccgaccta tcgcgaagct cgcgccgaaa gcgaccgcgc
    14281 tcaaggaaca gccctacatg cccgacgggc aacggacgcg cgggagcacc acacggtcaa
    14341 agcaccgcac gcccgtcagt tggccaggcg tttggcgaac tccgctgccg cggcgcccgg
    14401 gtcgtcggcg tccgtgatgg cgcgtaccac cacgacccgt tcaaccccgt acgaccggac
    14461 ctggtcgagg ttggccaggt cgatcccgcc gatcccgaac cacggccgcc cgccaccgag
    14521 cgacgccgcg tgccggagca gcgacggccc cggcgcgtgg cggcccggct tggtcggcgt
    14581 gggccacacg gggccgcagc agaagtagtc gacgccctcc tccacggccg cggcggacgc
    14641 ctcggcggtg gagtgggtgg accgtccgat gaagatgtcg tcgccgagta tctctcgcgc
    14701 gaccttcacc ggaagatcgt cctgccccag gtggagcacg tcgggccggg cggcgtacgc
    14761 gatgtcggcc cggtcgttga ccgccagcag cctgccgtgc cgatcgcagg cgtcgcggaa
    14821 gacctcgagg agcgcgagct cttcgcgtgc ctcgagtccc ttctcccgca gctggacgat
    14881 gtccacgccg gcggccagca ccgcgtcgag gaagtccgcc agatcaccgc gttcgcggcg
    14941 gccgtctgtg cagaggtaga ggcgggcgtc agaaagcgag ggcttgggca cgccgcttga
    15001 cctcggtatg gcgaccggcc ctgatggcgt cgacgggcga gccaggcagg gagtcgtcgg
    15061 gggtgaagag ccaccggagc gactcgacat cgtcgtaacc ggagtcccgc agcaccgaga
    15121 gggtgccagg caggcccttc atcacgtcct ttccatcaag gaacaccgcg ggcacttgtg
    15181 gcccgccacc accccggcgt acacccagca gcttgcggtc cttgaggagt tgcttggccc
    15241 gccccagcga gaggtcgagg cgcgcggcca cttcggggag agtgagccac tcggcaacga
    15301 gttggtcggt ctcccggtcg atctgcgcaa cagaaagcgt cacgaaacca caactaccac
    15361 atgccgtgct tgctcaaaca acacaatccc gtagggagac gtcgggatct accaggcatt
    15421 cggcgtcgac gcggtggccg ccttcgatga ttctgcggcc ctgtacgaga tctcgtggcc
    15481 gatccacggc gagtaccgcg gccagggtgt cgtccgaatt gagccagcag gccgaccatt
    15541 tgccttcgag ctcgcctcgg tagaggaggc ggtctccggc cgggtggtgg cccgcgtact
    15601 ggaccatgtg gccgaactgc tcggaccaga aatagggcac cgggtcgtaa accgagtccc
    15661 cgcccagcag cgtggcggcg gccacctcgg gtgagttgag cgcggcgtcc cagtgctcga
    15721 ccctgagccg ggtctggaag cggcgcgacc accaggcggc gcagtcgccc accgccacga
    15781 cgttcggcag ggaggtgcgc atgtgctcgt cggcgacgac gccgttgtcc aggtcgatgc
    15841 cggagccggc cagccagccg acggtcgggc gcaccccgac gccggtgacg acgacgtgcg
    15901 cctcgatgaa agcgccgtcg gccagcgtga tgccgccctc gtccacggag ccgaccaggg
    15961 tgtcgagccg caggtcgatg ccctcgtacc agccctgggt gcgggcgccg atctcgggcc
    16021 cgaccgcctg ggcgagcggg gtcgggccgg cctcgatcac ggtcacctcg cagccggccc
    16081 ggcgggcggc ggtggccacc tcggcgccga tccagccggc gccgatgatc accacgcggg
    16141 cgcccttgac gagccgggcg cgcagctcca gcgcgtcgtc cagggtgcgt agcacgtgct
    16201 gctggccgtc gccgggcagc gtgatcggct cggctccggt ggcgatgacc agaccgtcaa
    16261 aaccgagctc gccctcggag gtatcgacga cgccagggcg cagcgacttg gccgagacac
    16321 ccggccagaa gtccacctcc agcaccgcga gatcggcgtc gacgaagctg gagtcactgc
    16381 tgccggtcag gaccgccttc gacaggggcg ggcggtcgta cggccggtgc cgttcctgcc
    16441 caatgagggt gatcctgccg tcgaaccctc tcgcgcggag cgcctcgaca ctacgtacgc
    16501 cggccagacc ggcgcctgcc accacgacat gattcacgtc caagaccata acgggggccg
    16561 tgccggatcg tcgcgccgag gccgtaggct ggggtcgtaa gacgcgcggg agtccggccg
    16621 tttaccgggc tgagaggaag gctgcaccgg gccttcgacc gcaagacacc tgatccggat
    16681 catgccggcg aagggagcgg atgtggacat cgtcgtaggc ggcgggatcg tcgggctgtc
    16741 catcgcctgg cgcctggccc gctccggacg gccggtcacg gtggtcgacc ccgctccggc
    16801 ctcgggggcc tcgcacgcgg cggcaggcat gctggcaccg gtgagcgagg tcacgtacac
    16861 ggagcagcca ctgctccggc tgggcctcgc cggactgcgc cgctggccgt ccttcgcctc
    16921 cgaactcgcc gctgacgccg gccttggggc tgatacggga ctcgccgccg acattggccg
    16981 tggagtcggt acgggacttc gggctggtac gggacttggg gccggtacag gagtcgccgc
    17041 cgacaccggc cgcggggcct acacggaact cgccaccgtc acccgcgtcg acagacccgg
    17101 cgcggatggc aacgggcccg gtgggtcgaa ggctgacggc agcgggcccg gcgggtcgga
    17161 ggccgagggc agcgggccag gggcatctga ggaggccgtg agtggggtca gcgacgcggc
    17221 gcgggccggg ctggacttcc gggacgatgg gacgctcgct gtggcgttcg gggccgacga
    17281 tctggcggcg ctcggggagc tggccgcgtt catggagaag ttggggctac cggtcgaacg
    17341 gctgactggg cgcgaatgcc gccgcctgga gcccatgctg gcgccctccg tccgtggcgg
    17401 cctgctggcc cggggtgacg cgtgggtgga cccccgccgc gtcaccaccg cactcctggc
    17461 tgccctcgag cgcctcggcg tcccgctcgt acgggctcgc gtgagcgaac tgctccgcga
    17521 cggcgaccag gtcgtaggcg tacgcctcgc acccccggac cggacaccca ccccggacca
    17581 ggacctggca cgacgcacgc cccgcgccca ccggccctcg ggcgaggacc ccgtgcgacc
    17641 tgcacctccg gtcggtgagc ccgccgtagc ggcgggcggc ctcatccaga cgcacgtgcc
    17701 cgaggaaacc cggggcgacc agatcaccca ggcggaccta cccgacgaga tccggggtga
    17761 gcgggtcatc ctggcggccg gggcgtggag tgctgggctg gtcgatgtgc cggtgcggcc
    17821 ggtcaagggg cagatcatgc ggctgcgttc gccccagccg ctgcttggca ggtgcgtgcg
    17881 cgggacggtg cacggggcgt ccgtctacct ggtgcctagg ggtgatggcg agctggtggt
    17941 cggggcgacg caggaggagc tggggttcga cacgagggtg acggcgggcg ggctgtacga
    18001 gctgttgcgg gacgcccgcg agctggtgcc gggcgtcacc gagttggagg tggccgacgt
    18061 ggtggcgggg ttgcgaccgg gcacgccgga caacgtgccg ctcatcgggc ccagcggtac
    18121 gccgggactg gtgctggcca ccgggcatca ccggggcggg gtgctgctgg cgcctctcac
    18181 ggcggccatt ctgctgggcg aggaaggcga gatggcagag ctgtgctcgc cgctgaggta
    18241 tcgggatatt tcatgaatgt gaccatcaac ggggccgcgc atgaggtgcc cgacggcacc
    18301 accgtggcgc aggccatact cactctgacg gcggccacga ccggcgtggc cgtggccgtc
    18361 aacgacgagg tggtgacgcg gagtgcctgg gagacgacgg cgctcggcga cagcgaccgc
    18421 atggaggttc tgacggcggt gcaaggtgga tgatctgctg atcgccgggg agaagttctc
    18481 ctcccggctc atcatgggca ccggcggcgc gccatcgctg gaggtgctcg accaggcgct
    18541 ggtcgcgtcc ggcaccgagc tgacgaccgt cgccatgcgg cggctcgacc ccggtgcgcc
    18601 cggctcggtg ctcgacgtac tgcgcgagcg cggcatcaag gtcctcccca acaccgccgg
    18661 ctgcttcacc gccggcgagg ccgtgctgac cgcccggctg gccagggagg cgctcggcac
    18721 gaactgggtc aagctcgagg tcatcgccga cgagcggacg ctgctgccgg atccgatcga
    18781 gacgttcgac gcggcggagc ggctggtggc cgacgggttc gtggtgctgc cgtacatcgg
    18841 ggacgatccg gcgctggcgc gccgcctgga gctggccggg tgtgcggcgg tgatgccgct
    18901 cggcgcgccg atcggctcgg gcctcggcat ccgcaacccg cacaacatcg agctcatcgt
    18961 ggaggcggcc tcggtgccgg tgatcctcga cgcgggcatc ggtacggcca gcgacgccgc
    19021 cctggccatg gagctgggct gcgacgccgt actcctggcc acggccgtca ccagagcaca
    19081 gcggccggac ctgatggcga cggccatgag agcggcggtc caggcaggcc ggctcgcccg
    19141 ccaggcgggc cgcatccccc gccgccgcta cgcggaggcc tcctccccga caggcccgta
    19201 gcccggggcc acagaccgca ggcccccaga ccgagtgggg gtagcgggac gtcggtggct
    19261 tatgtccagt tgcgtactaa atgggcgcgt tcaaacgagc acggctcggc atcggtttcg
    19321 gatggtcagg ccttgccagt ggcaaaacgc ccgtaaactc agcggggtgg acacgacgac
    19381 tgcggacccc ctggtcggcc ggctgctcga tgggcgctat cgcatcgagt cccggatcgc
    19441 gcggggtggt atggcgaccg tctacctggc gctcgacgtc cggcttgacc gcacggtcgc
    19501 gctgaaggtc atgcatcgct cgctcgccga ggacccggcg ttcgtgcggc gattcatcgg
    19561 cgaggccaag tctgtggcca gcctctctca ccccaacgtg gtgcacgtct tcgaccaagg
    19621 caccgacacc gacgtggtct atctgtcgat ggagtacgtc cccggcaaga cgctccgcga
    19681 caccctgcgc gaccggggca ggctccccgc ccgcgaggcg ctggagatca tgataccggt
    19741 gctcgcggca ttgggcgcgg cccatcaggc cgggatggtg caccgcgacg tcaagcccga
    19801 gaacgtgctg ctcaccgacg acggccgagt caaggtggtg gacttcggcc tggcgcgggc
    19861 gatcgaggcg accaaccaga cccgtaccgg cgtgatgatc ggcacaatcg gctacatgtc
    19921 gcccgagcag gtcatgacgg gcggtgccga cgtgcggagc gacgtctacg cggcgggcat
    19981 catgctgttc gagctggtga ccggccagca gccctacgac ggcgagacgc cgatgtcggt
    20041 ggcctaccgc cacgtccatg acaccgtgcc gccgccgtcg tcggtggtgc cggaggtgcc
    20101 gccgctgatc gacacgctgg tgaggcacgc cacggcgcgc gcccccgacg accgtcccgc
    20161 cgacgcgacc gcgatgctgg tggcggccgt ggacgcgcac cgcatgctgc cccgtacgac
    20221 gacgccgccg acgcacacga ggacgtccca ggcgcactcc atgccctact cggcaccggg
    20281 ctcccgaacc ggcaccgcgc cgcactcgat gccgcaggcg gcgccgaacc acacgttgat
    20341 ccagccgcgc gaggaggtcc ccgcgcggcg cgccggtttc cggcccaact ggttcctggt
    20401 cgcgctcgcc gtcgtcatgg tggtggcggt ggcgctgacg ggctggtact tctcgcaggc
    20461 cacatacgta ccggtgccca acctggtcgg caaggacctg gcggtcgccg agaagctcgc
    20521 cgccggcagt ggcttcaagg tgaagacggc cgccggccag tacgacgaga agatcggcga
    20581 gggcctcgtg ctgcgcaccg acccggcatg gaacgtcgag ctcaagcgcg gcgacttcct
    20641 cacgctggtg ccctcgctgg ggccgaagcg ggtgctggtg cccaacgtcg agggcatgtc
    20701 cgagcccgag gcccgcaccg cggtcgccaa ggtcgggctc gacgtcaatc gcgtcagccg
    20761 gctggccaac caggaggtcg agcgcggcaa ggtgatccgc acctcccccg aggtgggcga
    20821 gaaggtcaag gaaggctcga aggtcaacat ctacatcagc gcggggctgg tgatgcccga
    20881 cgtcggtggc atgcccaagg acgaggcggc caactacctc cagacccagg gcttcaatgt
    20941 gcaggtcaac gaggtcgacg acgacgccga gccgtgcacg gtgatcgcgc aggcgccgaa
    21001 ggccaagtcc gaggtcgaca agggcgcaca ggccatgatc acggtggccc ggtgccagac
    21061 cgacttct
//
