LOCUS       NZ_JAHFZZ010000004     22577 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Nonomuraea sp. NEAU-A123 Scaffold4, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZZ010000004
VERSION     NZ_JAHFZZ010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea sp. NEAU-A123
  ORGANISM  Nonomuraea sp. NEAU-A123
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 745880)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Nonomuraea triticisoli sp. nov., a novel actinobacterium isolated
            from rhizospheric soil of wheat in Langfang, Hebei Province, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 745880)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, Changjiang Road No. 600, Xiangfang
            District, Harbin, Heilongjiang Province 150036, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603905.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 04:26:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,983
            CDSs (total)                      :: 11,901
            Genes (coding)                    :: 11,761
            CDSs (with protein)               :: 11,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 28 of 140
            Pseudo Genes (incomplete)         :: 121 of 140
            Pseudo Genes (internal stop)      :: 3 of 140
            Pseudo Genes (multiple problems)  :: 12 of 140
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:52:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 28157
            Orig. end                         :: 50734
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZZ010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22577
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22577
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22577
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12577](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12577)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(266..1018)
                     /locus_tag="KLK06_RS12405"
                     /old_locus_tag="KLK06_12390"
     CDS             complement(266..1018)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024852.5"
                     /locus_tag="KLK06_RS12405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12390"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_214635565.1"
                     /transl_table=11
                     /translation="MRVAVAGGTGLVGRYVVEELAAAGQEPVVLARSRGVDLVTGAGLD
                     AAMTGVAAVVDVSNVTTMSGRKARSFFDSVGRNLLNAGERAGVKHHVTLSIVGIDRVES
                     GYYQGKLRQEETVKAGRTPWTVLRATQFHEFAQQVLDRVAKPLAVVPRMRTQPIAAREV
                     AQHLVGLVLSPAQGMAPELAGPRVEQLVGMVHRLLRARNQRRLLLPVKYPGATGAAMTG
                     DGQLPTGRGPRGSQTFDEWLARSLAQEG"
     gene            complement(1053..1481)
                     /locus_tag="KLK06_RS12410"
                     /old_locus_tag="KLK06_12395"
     CDS             complement(1053..1481)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_12395"
                     /product="hypothetical protein"
                     /protein_id="WP_214635566.1"
                     /transl_table=11
                     /translation="MNTTKLRYASLGLLAVSALYTGIWAYFSPEGWHANFPGFGRSWLP
                     QLGPYNEHLAKDAGAMFLAMAVLTIITLRYVRNDRVVRTTGAVWLVFNLLHLIYHMQHL
                     HMYEPSDQILNVVALSSLAVLSAVLLVPSLPGRRHDTR"
     misc_feature    1649..1660
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.53"
                     /tool="antismash"
     gene            complement(1706..2851)
                     /locus_tag="KLK06_RS12415"
                     /old_locus_tag="KLK06_12400"
     CDS             complement(1706..2851)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (95-235). E-value:
                     4.4e-13. Score: 41.3. Matches aSDomain:
                     nrpspksdomains_KLK06_RS12415_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590898.1"
                     /locus_tag="KLK06_RS12415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12400"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_214635567.1"
                     /sec_met_domain="PF00561 (E-value: 9.5e-10, bitscore: 33.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEITAFLIKIPQDRLDDLRHRLAQTRWPDELPGAGWEAGVPLG
                     YLKDLADYWRTGYDWRAHEARLNEFPQFTTDIDGQIVHFLHVRSPEPGALPLVITHGWP
                     GSVVEFMKIIGPLTDPASHGGDPADAFHVVAPSLPGFGFSSPLAAAGWNTSRVARAWAE
                     LMQRLGYHRYGAQGGDTGAIVSPELGRIDPDHVIGVHVNNLGTFPSGDPAELAGLTEAD
                     QARLGLMTTWGRDMSGYAIVQSTRPQTISYALTDSPVGQLAWIVEKFKEWTDPSAGLPE
                     DAIDRDQILTDVSVYWLTGTAGSAARIYYEGARTWGQAQARSPVPTAVAVFPNDLTLRP
                     LAERDHNVVRWTEFSRGGHFAAMEAPDLLVNDVREFFRQYR"
     aSDomain        complement(2147..2566)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS12415_Abhydrolase_1.1"
                     /evalue="4.40E-13"
                     /label="KLK06_RS12415_Abhydrolase_1.1"
                     /locus_tag="KLK06_RS12415"
                     /protein_end="235"
                     /protein_start="95"
                     /score="41.3"
                     /tool="antismash"
                     /translation="PLVITHGWPGSVVEFMKIIGPLTDPASHGGDPADAFHVVAPSLPG
                     FGFSSPLAAAGWNTSRVARAWAELMQRLGYHRYGAQGGDTGAIVSPELGRIDPDHVIGV
                     HVNNLGTFPSGDPAELAGLTEADQARLGLMTTWGRD"
     gene            2913..3863
                     /locus_tag="KLK06_RS12420"
                     /old_locus_tag="KLK06_12405"
     CDS             2913..3863
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540044.1"
                     /locus_tag="KLK06_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12405"
                     /product="YafY family protein"
                     /protein_id="WP_214635568.1"
                     /transl_table=11
                     /translation="MLETSARLLQLLSLLQTPRDWTGADLAQRLEVDVRTVRRDIQKLR
                     DLGYPVHATPGAAGYRLGAGTKLPPLLLDDEEAVAVAIGLRTAASGTVSGIEETSLRAL
                     AKLEQVLPSRVRHRVNLLHSVTVTVPTGGPTVDPDVLTVLAAACREHERLRFDYRNHDG
                     TDSVRDTEPHRLVHTGRRWYLVGWDTDRRDWRTYRADRIRPRIPTGPRFTPRQAPDVDL
                     AGYLAHGVSTAAYRYQARITLYAPAETAAERIPPTIGVIEAVDPHSCLLHTGSNSLDEI
                     AVYVALFGFRFRIHQPPELIAHIRDLAARLTDAID"
     gene            complement(3988..4878)
                     /locus_tag="KLK06_RS12425"
                     /old_locus_tag="KLK06_12410"
     CDS             complement(3988..4878)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013530.5"
                     /locus_tag="KLK06_RS12425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12410"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_214635569.1"
                     /transl_table=11
                     /translation="MTFHVIVGRGATASKTALLLAEDGERVRMISRTGGGPEHPLIDKV
                     AADATDADRLTELTEGADTLFTTAAPPYHTWPEQFPILSASLLTAVKRTGVAYVMLGNL
                     YAYGPVDGPIRPDFPLAATGPKGRTRALVWEEAAASGVKVTEVRAAQFYGAGAFSVFSL
                     MVQRQVLEGRLAVVPQELDIPHSYSAIGDTARTLVAASRNEQAYGRAWHAPTSTLSVRE
                     LAGRLAGLAGAPAPRVEEMTERDLTLLAFTEPFWAELHEVLTKPGHPFVIDYSETEKIL
                     GVGATPVDDVLQEVI"
     gene            4950..5918
                     /locus_tag="KLK06_RS12430"
                     /old_locus_tag="KLK06_12415"
     CDS             4950..5918
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622893.1"
                     /locus_tag="KLK06_RS12430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12415"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_214635570.1"
                     /transl_table=11
                     /translation="MHRVAAVIVPPVLSFDVSIPLMVFNSVPDYDVRVCTARPGPVPTV
                     GGPDIVVTDGLDTVQDADTVIAVGSGGEPAPPEVLDTLRKAADSGARIASLCTGAFVLA
                     QAGLLDGRRATTHWGLAGDLATRFPSIDVQPNLLFVEDGGIFTSAGAAAAIDLCLHLVR
                     IDYGAAVANTAARLAVVPPVRPGGQAQFIETPLPPERGTSLAPTRAWALAHLDRPLTLA
                     ELAGQAKTSVRTLTRRFHAETGLSPLQWLLHRRIDRARELLETTELPMDQVADKSGLGS
                     ADSLRKHMVGRVGLTPRAYRASFTRVPTGTSPEPGNMTSLR"
     gene            complement(6119..6331)
                     /locus_tag="KLK06_RS12435"
                     /old_locus_tag="KLK06_12420"
     CDS             complement(6119..6331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542825.1"
                     /locus_tag="KLK06_RS12435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12420"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_214635571.1"
                     /transl_table=11
                     /translation="MNVHDELAAAIWRKAAKSGANGGDCIEVASLSGGRVAFRDTERPD
                     LAPYVVSGSVWAAFMDGAKNGEFDF"
     gene            complement(6318..7016)
                     /locus_tag="KLK06_RS12440"
                     /old_locus_tag="KLK06_12425"
     CDS             complement(6318..7016)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="KLK06_RS12440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12425"
                     /product="DUF5753 domain-containing protein"
                     /protein_id="WP_214635572.1"
                     /transl_table=11
                     /translation="MTYVPQRPSDSTPSLEFTEGVERFLGLKGELIRLWPLVTKTASPA
                     WFREWPKIEGEACTLRTWQPLVIPGLLQTRGYARAVLQGQPGITEDQVNEALEARLARQ
                     VIFTRSAPPIYSAIIDEVVLSRPIGGPEVMKEQLEHLVKLLSHPCITLQVVPMAAVPTI
                     GLLGGFVIASPLKGGDTIYLDSAADGEVTDREDKVRTVSVRYDAIRSWARPVNETEDAI
                     REKMVTYERP"
     gene            complement(7152..8825)
                     /locus_tag="KLK06_RS12445"
                     /old_locus_tag="KLK06_12430"
     CDS             complement(7152..8825)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="KLK06_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12430"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_214635573.1"
                     /transl_table=11
                     /translation="MSDGAHQRRLGELLTELKDRSGYSYAAIGRKANVSKSAVHRYCVG
                     LSVPQTFGAIESIARACGADWATMNRLYAEWAVASEAAEPAPPKEEEEPAPPKEVEETP
                     PPEAPAERPGPIRRHARALAATAVVFSIVLTATVIVLRSPAQPAPAQSGGPGIEQQISG
                     PAWALPPEPVPRTLFGATLNSSSGAMPDFDLGAVRFWDSETRWSQVEPQRGVFDWRTLD
                     SLVAGAQRAGLPALYVAGGTPAWAAPDGAHSVYPEGARSAPPDDLAEWDRFIRALAHRY
                     RGRINAYELWVLASDKRMYTGTPETLVVMTRRASAIIRSIDPKATIVCPGMGNLWTAEG
                     RQILQRFAELGGYDHCDVAGIKLYQQAATDPPETMLDLLGAVDRLFHEAGVHPRLWNTG
                     TTYTIALQQPLDQAMARNYAVRFFLVGMYARNYHLERMYFYNWGGTKIPIVLQAEGGKP
                     TAAARAVETLQSWLASAQSRSCGHGLSAGLPSNAWQCEFTIGSGAAAHPAAVQWTQSGA
                     AAIRANAAVISVRHLDGRVDHPSPGETLHITGEPILIEYA"
     misc_feature    complement(7362..7364)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8817..8830
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            9230..9862
                     /locus_tag="KLK06_RS12450"
                     /old_locus_tag="KLK06_12435"
     CDS             9230..9862
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_12435"
                     /product="hypothetical protein"
                     /protein_id="WP_214635574.1"
                     /transl_table=11
                     /translation="MASGKSRGLRHIAILFAVAVAAVGLPAPTAASADDAPSAQVQVQV
                     QVQPTIGDDGKPTNLAPKPTGLTPLQPTPNATPSVEGSTAATVLVECCGLVVRYDSIQN
                     LVVAANINATNVGKGSNCNIWNWGGGNVWNPVNPGGNCDTRSMNGHTYSWAIWSDTDAF
                     TVQYEAYWLNFHGSWRRLGANVYTKINGAETAKCYRESDGVNCYVVY"
     misc_feature    9302..9304
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12577)
                     /gene="lanL"
                     /locus_tag="KLK06_RS12455"
                     /old_locus_tag="KLK06_12440"
     CDS             complement(10001..12577)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="KLK06_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12440"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_214635575.1"
                     /sec_met_domain="Pkinase (E-value: 3e-15, bitscore: 51.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.9e-21, bitscore:
                     69.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVTLTHFAESNSREIYEGDTWVSVHDPRATTPNQGWKLHVSARP
                     GTLAATLDRVLPVLAGVSCDFKVARSPDKLAELNSGDLDPGAVGKAITVYPQPDEVVPL
                     GHRLAEALAGLAAPRIVSDRRVRPDAPVYYRYAPFAPQYRVDENGDFELIIVGPDGEHL
                     PGAAGPEFDCPPWATDPFRPQGSVPGPSRESTDGQGTGETPAKLIGNRYRLTSGVARGP
                     RGNVYRAEDADGRPVVVKESRAYVGENAEGWDLRMYLRNELRILKALDGVAGVPTPIDH
                     FRHGDDEFLVMTDAGSLDLNRFVGERGRFTEDSDFTETSGGRDLAALAGRLLEVLDAVH
                     ARGVVVRDFSPKNVVLGEDGACTLIDFGNSRYEGLQLPGWSRGYSVPGQQEDRPSEPAD
                     DYFSLGATLFFAATGMNPIMIDSDQARNVERTVMCLARMFPGVTTGVIGLVPRLLSLDA
                     EERVAAAADMRAGAGRPGRAVSRPDGVRFSGDLLSRVLDHTTRACVRFAEGLMDGPADR
                     TASPPVTNVYGGSAGIGMELLHHPEAKAVAADLARWTARVMPPTALPPALYFGRTGTAL
                     FLTAARLTAVPELPDPGPIVLAGEQRADQAHGVAGIGAGHLSLAALEQDPRHLEVAAEC
                     ARLLISGEVTDSKDAVAPAQAGSGVNVEMAFAHGAAGCAEFLLSYHEATGDPDAGQAAR
                     ERFESLATATEAMLGELTGPDAKAMGASWCQGVSGILGPLAHAATAYGEDRYLDLAERG
                     ARASLAIAPQAWVVSQCCGLSGIGEALIDLAMATGDDAYWRGAEEVVELMLMRAGGEFS
                     APVFTGNDLDKPGYTWATGASGVLSFLRRLDRRTGPRLWTANWRLP"
     misc_feature    12568..12582
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            complement(12721..12891)
                     /locus_tag="KLK06_RS12460"
                     /old_locus_tag="KLK06_12445"
     CDS             complement(12721..12891)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038148.1"
                     /locus_tag="KLK06_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12445"
                     /product="SflA family class IV lanthipeptide"
                     /protein_id="WP_214635576.1"
                     /transl_table=11
                     /translation="MSVLTLEPRDAGALEYEDLAIDFEGELTALLHGPQACVNTCKRTV
                     CSTFPCCPSIV"
     misc_feature    complement(13019..13033)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.55"
                     /tool="antismash"
     gene            13162..15051
                     /locus_tag="KLK06_RS12465"
                     /old_locus_tag="KLK06_12450"
     CDS             13162..15051
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620956.1"
                     /locus_tag="KLK06_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12450"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_214635577.1"
                     /transl_table=11
                     /translation="MKSFWKKRPPDVPADRSGLAVAYWESHDDELLTASLSKIARRLPY
                     LVMSALRMAWEAHRRDTIIALAGNLAAGVFTVYGLVATSDVLASLFAGGPTPERIRAAL
                     PSLALVAAAAGLRGTLLTAATWAQARLKVQVERLAETRLFELTTQVELTAFDDDEFHNA
                     MRRARDSGVPDAAGVVEATVAVIGGAVGVLASAVALGLMHPLLTPLLLVTVVPAGWAAI
                     RAARLQYQAYYRLSAARRRKFMLSDLMAERLPAAEVRAFALRDFLLGEYGNVADLEQDV
                     QLDVARRRAVTKAAGDLLTGAATVAVYAALAGLLAVGVIPLAVAGAAVLAIRAGQLSLA
                     GLVQMMNRLYEAGLYFGDYLSFRALAASRVRQPSGTAAPEPSGRLTADRVTFSYPGASR
                     PALTGISVSVGFGEVIALVGENGSGKTTLAKLLAGLYRPDSGTIRWDGADLADLDTRGL
                     ISVIAQDHTRWPLTLRENILMGRPLDEERLAAAAAAAGADEVVAGLSQGYDSLLDQRFR
                     GGHDLSGGQWQRIAVARGFYRDAALVIFDEPTSALDARAEHALFERIRKHADGRSIVLI
                     THRLASVRYADRIYVLDHGRVAQQGTHAELMESGGPYADMYTLQAQAYREAVT"
     gene            15095..15958
                     /locus_tag="KLK06_RS12470"
                     /old_locus_tag="KLK06_12455"
     CDS             15095..15958
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.5"
                     /locus_tag="KLK06_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12455"
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_214635578.1"
                     /transl_table=11
                     /translation="MIILASAYAALIAVLLYAAVSKARDLPGFAADIAGYRLIPQRLTT
                     AAAVTVVGAELVAAGLLTAPATRRWGALLAAALFAAFLAAMASVLRRGLSVGCGCFGDH
                     DLVGPATVTRTGLLAVLAVMAAVAGASPFTFVHLLVGAAYLALTFLPVRLIGAVERGRI
                     GPRPGTRWDVTPQAAALTPEKLGVLYALIGPACGVCSAMLPAFVAVERVDVVLVSAAEE
                     GQVRDYLAAHEVELPLVIDPGVFDRHGIPWPPYAVLTDRRGVVLAAGGVAEPGALDALL
                     GNGLSG"
     gene            complement(15960..16604)
                     /locus_tag="KLK06_RS12475"
                     /old_locus_tag="KLK06_12460"
     CDS             complement(15960..16604)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653826.1"
                     /locus_tag="KLK06_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12460"
                     /product="HAD family hydrolase"
                     /protein_id="WP_214635579.1"
                     /sec_met_domain="HAD_2 (E-value: 1.5e-20, bitscore: 69.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLALFDLDNTLIDRLDAFRRWAAEFAADRGLGSADVAWMIELDAD
                     GSLPMSTFFTHVRERFALAESADSLWRGYRDRLPHLVTCRPAVLESLDRLRLSGWRVGI
                     VTNGMTDNQSGKIHHSGLVDRVDGWAISDAEGFSKPAAELFEIAAQRCGTTLADGGWMV
                     GDDVEKDVAGGRGAGLRTIWIDRGQSAGRSPGADHEVTDVLDAITMLDADL"
     misc_feature    complement(16614..16629)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            16711..17802
                     /locus_tag="KLK06_RS12480"
                     /old_locus_tag="KLK06_12465"
     CDS             16711..17802
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850566.1"
                     /locus_tag="KLK06_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12465"
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="WP_214635580.1"
                     /transl_table=11
                     /translation="MLTRRLFASALAVLTGGTVAVVLLQPHAATAERRGQAPVVIGHRG
                     ASAHRPEHTLLSYEAAIAMGADYIEPDLVSTKDHILVARHENDITGTTDVAAHPEFADR
                     RTTKTVDGRPITGWFTEDFTLAELKTLRAKERVPDLRPDNTAFDGVAEIPTFEEVVRLA
                     QRHGVGVYPETKHPTYFDSIGLSLEEPLLDILNANHVRKAYIQSFETANLRELRKKTRL
                     PLIQLITFGGAPYDWVAAGDQRTYDDMVKPEGLREVASYASGIGVDTRRVVPVGADGKL
                     VEPTTLVEDAHRRRLDVHVWTIRNENSQLPLDYRLGNPASPAFPRATGDVMGWLTRLLD
                     LGVDGAFCDDPAMGRAVVAQRSR"
     misc_feature    16726..16728
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17828..19363)
                     /locus_tag="KLK06_RS12485"
                     /old_locus_tag="KLK06_12470"
     CDS             complement(17828..19363)
                     /NRPS_PKS="Domain: AMP-binding (8-420). E-value: 1.5e-105.
                     Score: 345.0. Matches aSDomain:
                     nrpspksdomains_KLK06_RS12485_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017539288.1"
                     /locus_tag="KLK06_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12470"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_214635581.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-111, bitscore:
                     367.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNLSIVLEDSARNTPDGTALVFGDMRLPYSMIDTVANQVANLLV
                     SRGIAKGDKVALACPNLPYFPFVYYGILKAGATVVPLNVLLQSREIAYHLDDSDAKALF
                     CFEGTPELPLGERGKAGFEGSEGCEHFFVLPATPLATESEYGESIWAALGGMPGEFETV
                     QTAPDDTAVILYTSGTTGQPKGAELSHQNMLLNAMAGDKMFPRSDGGDTYLAVLPLFHS
                     FGQTVVMNTGFLRGATVVLMPRFEPGEAVALMRKEGVTFFAGVPTMYWGMLTKIHAEGA
                     EVPTTLRVAVAGGASSPVEVLKDFQQTFGLDILEGYGLSETSPVASFNQLGRPTKPGTV
                     GTPIWGVEMKLIDGDWKTIEGEGPGEIAIRGHNIMKGYYGRPEATADVLRDGWFRTGDI
                     ATRDADGYYSIIDRSKDMIIRGGFNVYPRELEEVLMTHEAVSLAAVVGVPHDSHGEEIK
                     AYVIRTAGSTTTEEELIAWAKENMAAYKYPRVVEFRDALPMTATGKILKRELR"
     CDS_motif       complement(17954..17989)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS12485_0005"
                     /evalue="4.60E-01"
                     /label="NRPS-A_a3"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="470"
                     /protein_start="458"
                     /score="4.1"
                     /tool="antismash"
                     /translation="AYVIRTAGSTTT"
     aSDomain        complement(18104..19339)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS12485_AMP-binding.1"
                     /evalue="1.50E-105"
                     /label="KLK06_RS12485_AMP-binding.1"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="420"
                     /protein_start="8"
                     /score="345.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EDSARNTPDGTALVFGDMRLPYSMIDTVANQVANLLVSRGIAKGD
                     KVALACPNLPYFPFVYYGILKAGATVVPLNVLLQSREIAYHLDDSDAKALFCFEGTPEL
                     PLGERGKAGFEGSEGCEHFFVLPATPLATESEYGESIWAALGGMPGEFETVQTAPDDTA
                     VILYTSGTTGQPKGAELSHQNMLLNAMAGDKMFPRSDGGDTYLAVLPLFHSFGQTVVMN
                     TGFLRGATVVLMPRFEPGEAVALMRKEGVTFFAGVPTMYWGMLTKIHAEGAEVPTTLRV
                     AVAGGASSPVEVLKDFQQTFGLDILEGYGLSETSPVASFNQLGRPTKPGTVGTPIWGVE
                     MKLIDGDWKTIEGEGPGEIAIRGHNIMKGYYGRPEATADVLRDGWFRTGDIATRDADGY
                     YSIIDRSKDMIIR"
     CDS_motif       complement(18203..18274)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS12485_0004"
                     /evalue="3.30E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="387"
                     /protein_start="363"
                     /score="22.7"
                     /tool="antismash"
                     /translation="PGEIAIRGHNIMKGYYGRPEATAD"
     CDS_motif       complement(18470..18499)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS12485_0003"
                     /evalue="9.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="298"
                     /protein_start="288"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="VAVAGGASSP"
     CDS_motif       complement(18794..18853)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS12485_0002"
                     /evalue="2.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="190"
                     /protein_start="170"
                     /score="23.1"
                     /tool="antismash"
                     /translation="AVILYTSGTTGQPKGAELSH"
     CDS_motif       complement(19115..19153)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS12485_0001"
                     /evalue="1.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="KLK06_RS12485"
                     /protein_end="83"
                     /protein_start="70"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GILKAGATVVPLN"
     gene            19546..21090
                     /locus_tag="KLK06_RS12490"
                     /old_locus_tag="KLK06_12475"
     CDS             19546..21090
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893571.1"
                     /locus_tag="KLK06_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12475"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_214635582.1"
                     /transl_table=11
                     /translation="MEYDYVIVGAGSAGCVLANRLSADPGVSVALVESGGQDDKLEIRM
                     PAGFAKLFKTDYDWNYTTAKQSEMSGRELYWPRGRVIGGSSSINAQMWVRGCQQDYDQW
                     GIPGWTYDDVLPYFTKAEHRVGSNGGGVYGSTGPLFISELRSPNVTTAAFLKACEELGL
                     ARLDELNGRSNEGFSATPVTQNRGRRWSSADAYLRPALKRPNLTVITGATVDRVVFDGA
                     RAVGIEHDGGAQVKAKREVILSAGAIGSPYLLMRSGVGAADELRDAGVTIVRDLPEVGK
                     NLQDHLSTGVYVQSKQPVTLTKAESIGNLLRYIVLRSGMLTTNVGEAVAFIRTSPEEPA
                     PDIELIFAPGPFIDHGLTPPTGHGLTVGVVLLQPESRGRIGLNGREVVIDPGYLSKEAD
                     VKRLIAGLKTAKQVFATAAMKEYAGGPMAPYTGPESDADLAQWIRERGETLYHPVGTCR
                     MGTDAESVVDPSLKVRGLDGLRVVDVSIMPTLNRGHTHAPAIMIGEKGAELIAKRS"
     misc_feature    20032..20034
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    21092..21103
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            21122..22375
                     /locus_tag="KLK06_RS12495"
                     /old_locus_tag="KLK06_12480"
     CDS             21122..22375
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544568.1"
                     /locus_tag="KLK06_RS12495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_12480"
                     /product="cytochrome P450"
                     /protein_id="WP_214635583.1"
                     /sec_met_domain="p450 (E-value: 3e-16, bitscore: 54.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISSDLDISQLMFWGLPQAERMAVFRRLRQLDQPVFLAEQAVPF
                     IKGGPGYYALVRHADVSEASRNAAVFSSEPCSNSVPDMPRWLAVYFGSMINMDDPRHAR
                     LRRIVSRAFTPRILSKMEEDLATAAAEIVDQAIEEGPGDFVAQIAARLPVRVICDMMGI
                     PATFHDMVLRRTNVILGNADPEYTGIDPEFSRVNVARGLAKLLHAGFSLNRLAARLGDE
                     RRRHPTGDLVSLLVNGEERLTSQELGSFFILLVVAGSETTRNAIAYGLKLFTDHPDQRE
                     LLLDDFDGRVTKACDEIVRYSTPVIQFRRTLTRDHEMNGMSYKKGDKVLLFYNSANRDE
                     TVFRDPDAFDITRDPNPHVGFGGPGPHYCLGAHLARREMTVMFRELFTRLPGIRSEGEP
                     DFLLSNFINGIKHLKYTF"
ORIGIN
        1 ctcgcggcgg acccgcgctg aggcgaggtg gtcgaggcag atccgcgagg cgacccgggt
       61 cagccatgcc agcggcacgt cgatctcccg ctgcccttcc tcggacaggg cgtaccagcg
      121 ggcgtaggtc tcctggacga cgtcctcggc gtcctgcacg gacccgagca tgcggtagcc
      181 gagattgagc agtctgcggc gttcgaccat gagggagccg aggctggggt cctgggcggg
      241 cccgggtggc gtggacacgg cttgctcatc cttcctgggc gaggctgcgg gcgagccatt
      301 cgtcgaaggt ctggctgccg cggggtcccc gtccggtcgg caactggccg tcgcccgtca
      361 tggcggcgcc cgtggcgccg ggatacttca ccggcagcag gagccgacgc tggtttcggg
      421 ctcggagcag ccggtgcacc atgccgacga gctgctcgac gcgcggtccg gcgagctccg
      481 gtgccatgcc ctgcgccggg gacaggacga gtcccacgag gtgctgggcc acctcgcggg
      541 ccgcgatcgg ctgggtacgc atccggggca ccaccgcgag aggcttcgcc acccggtcga
      601 ggacctgctg cgcgaactcg tggaactggg tggcccgcag caccgtccac ggcgtccgcc
      661 cggccttgac cgtttcctcc tggcggagtt tgccctggta gtagccggat tcgactcgat
      721 cgatgccgac gatcgacagc gtgacgtggt gcttcacccc ggcccgctcg ccggcgttca
      781 ggaggttgcg gccgacgctg tcgaagaacg accgcgcctt cctgccgctc atggtcgtca
      841 cgttgctcac gtcgacgacc gccgccacgc ccgtcatggc cgcatccagc cccgcgcctg
      901 tcacgaggtc cacgccccgt gatctggcca gcaccaccgg ctcctgcccg gccgcggcca
      961 gctcctcgac cacgtaccgg ccgaccagcc cggtcccgcc tgccaccgct acccgcatgc
     1021 cgcgcctccc ctcgccccta tgttcctgtc cgtcatcgtg tgtcgtgtcg ccgtccgggg
     1081 agtgacggca ccagaagcac ggccgacagc accgccagcg aggacagggc gacgacgttg
     1141 agtatctggt cgctcggctc gtacatgtgg agatgctgca tgtggtagat caggtgcagc
     1201 aggttgaaga ccagccacac cgcacccgtc gtccgcacga cccggtcgtt gcgtacgtag
     1261 cgcagggtga tgatcgtcaa gacggccatc gccaggaaca tcgccccggc gtccttggcg
     1321 aggtgctcgt tgtaggggcc cagttggggc agccagctcc gtccgaagcc ggggaagttc
     1381 gcatgccatc cctccggcga gaaataggcc cagatacctg tgtacagcgc ggacacggcc
     1441 aagaggccga gactggcgta ccggagtttc gtcgtgttca taccccagtg acgagacagc
     1501 acccgccgat gtgaggtggc gggtgagctg acctctgtgt atgtacaggc tcagaagctt
     1561 ggcggctggg ctgcgaccat cgacgaaccc gccgacaccg ccgcgcccgc gctgagagag
     1621 gcgcgctccg gctggttcgg cgctccctga aaacgcgttc gccggtccga tcgagccgcg
     1681 cgtgtccggg agggcccgat tgctgtcagc ggtactggcg gaagaactcc cgcacatcgt
     1741 tgaccaggag gtcgggtgcc tccatggcgg cgaagtggcc gccgcggctg aactcggtcc
     1801 agcgcacgac gttgtggtcg cgttcggcga ggggccgaag ggtgaggtca ttggggaaca
     1861 ccgccaccgc ggtcggcacc ggagaccgcg cctgggcctg accccaggtg cgggcgcctt
     1921 cgtagtagat gcgggccgcg gatccggctg tgccggtcag ccagtacacc gaaacgtcgg
     1981 tgaggatctg gtcgcggtcg atggcgtctt cgggcaggcc ggcgctcgga tcggtccatt
     2041 ccttgaactt ctcgacgatc cacgcgagct ggcccacggg tgagtcggtg agggcgtagg
     2101 agatcgtctg cggccgggtc gactggacga tggcataacc ggacatgtcg cggccccagg
     2161 tcgtcatgag cccgaggcgg gcctggtcgg cctcggtgag gccggccagc tcggccggat
     2221 caccggaggg gaaggtgccc aggttgttga cgtgcacgcc gatcacgtga tcggggtcga
     2281 tgcggccgag ttcgggggag acgatcgccc cggtgtcccc gccctgcgcg ccgtagcggt
     2341 ggtagccgag gcgttgcatc agctcggccc aggcgcgggc cacccggctg gtgttccagc
     2401 ccgcggcggc gagtgggctg gagaagccga agcccggcag cgacggggct accacgtgga
     2461 aggcgtcggc ggggtccccg ccatggctcg cagggtcggt caacgggccg atgatcttca
     2521 tgaactccac gaccgagccc ggccagccat gggtgatgac gagcggcagc gctcccggct
     2581 ccggcgaacg gacgtgcagg aagtgcacga tctgtccgtc gatgtcggtg gtgaactgcg
     2641 gaaactcgtt cagccgcgcc tcgtgggcgc gccagtcgta accggtgcgc cagtagtcgg
     2701 ccaaatcctt caggtagccc agcggcaccc cggcctccca gccggcgccg ggcagttcgt
     2761 ccggccaacg ggtttgggcg agccggtgac gcaggtcgtc gaggcgatcc tgagggatct
     2821 tgatcagaaa tgcggtgatc tcttcgctca tgacagccac gctatgagca ggctaggaca
     2881 gcttctgccc taggacgagt aatctgcgga acatgttgga aacgtccgcc cggttgctgc
     2941 agttgctctc gctgctgcag accccgcgcg attggaccgg cgccgacctg gcgcagcgcc
     3001 tcgaggtcga tgtgcggacc gtgcgccgcg acatccagaa actccgtgac ctcggctacc
     3061 cggtgcacgc cacccctggc gcggccggct atcggctcgg cgccggaacg aagctcccgc
     3121 cgctgctgct cgacgacgag gaggccgtgg ccgtcgccat cgggctgcgc accgccgcca
     3181 gcggtacggt cagtggcatc gaggaaacct cgctacgcgc actggccaag ctcgaacagg
     3241 tactgccgtc acgcgtacgg caccgggtca acctgctgca ctcggtcacc gtcacggtcc
     3301 ccaccggcgg tcccaccgtg gacccggacg tgctgaccgt gctcgcggcc gcctgccgcg
     3361 agcacgaacg gctccgcttc gactatcgga accacgacgg caccgactcg gtacgcgaca
     3421 ccgaacctca ccggctggtc cacacgggcc ggcgctggta cctggtgggc tgggacaccg
     3481 accggcgcga ctggcgcacc taccgggccg accggatccg tccccgcatc cccaccggcc
     3541 ctcgcttcac cccccggcag gcccccgacg tcgacctcgc cggctacctc gcgcacggcg
     3601 tctccaccgc cgcctaccgc taccaggccc ggatcaccct gtacgcgccg gccgagaccg
     3661 ccgccgaacg gatcccgccc accatcggtg tcatcgaggc cgtcgacccg cacagctgcc
     3721 tgctccatac gggatccaac tcactcgacg agatcgccgt ttacgtcgcg ctgttcggct
     3781 tccgcttccg gatacaccag ccacccgaac tgatcgcgca catccgagac ctcgccgccc
     3841 gactcaccga cgccatcgac tgagttcccg tttgcgtcac ccgatcaggc tggtgtccac
     3901 cgtgggctca gaggtggctc gccgcgaacc tgcccggggt ggcacgttcg ggagctgggc
     3961 gcacggcgaa cgtccctcgt cacagcatca gatcacttcc tggagcacgt cgtcgaccgg
     4021 tgtggcgccc acgccgagaa tcttctcggt ctcggagtag tcgatgacga acgggtggcc
     4081 gggcttggtg agcacttcgt gcagttctgc ccagaacggc tcagtgaacg cgagcagggt
     4141 cagatcgcgt tcggtcatct cttccacccg tggcgccggt gcccccgcga gtccggcgag
     4201 tcgcccggcc agttcccgca ccgacagggt cgaggtgggt gcgtgccagg cccggccgta
     4261 cgcctgctcg ttgcggctcg cggcgaccag cgtgcgtgcg gtgtcgccga tcgccgagta
     4321 gctgtgcggt atgtcgagtt cctgcggcac cacggcaagc ctgccttcaa ggacttgccg
     4381 ctgcaccatg agactgaaca ccgagaaggc gccggcgccg tagaactgag cggcccgcac
     4441 ctcggtgacc ttcacccctg aagcggcggc ttcctcccag acaagcgccc tggtccgccc
     4501 cttgggcccg gtcgcggcca gcgggaagtc cggcctgatc ggcccgtcca ccggcccgta
     4561 ggcgtagagg ttgccgagca tgacgtaggc gaccccggtc cgcttcactg cggtgagcag
     4621 tgacgccgac aagatcggaa actgctcggg ccaggtgtgg tacggcggcg cggcggtggt
     4681 gaacagcgtg tccgccccct ccgtcaactc ggtgagccga tcggcgtcgg tcgcgtccgc
     4741 ggcgaccttg tcgatgagcg gatgctcggg ccctccacca gtacggctga tcattcgcac
     4801 ccgctcgccg tcctcggcca gcagcagagc ggtcttcgac gcggtggccc cgcgacccac
     4861 gatcacatga aatgtcatga ggacaacggt gccgactggc ggcctcgtag catagtggcc
     4921 ggaatgccga ctatccggag gatctggcca tgcaccgtgt cgccgccgtc atcgtgcccc
     4981 ccgtgctgag cttcgacgtc tcgatccccc tcatggtgtt caacagcgtt cccgactatg
     5041 acgtgcgcgt ctgtacggcg cggcccggcc cggtgccgac cgtcgggggc cccgacatcg
     5101 tggtgacgga tggcctggac acggtgcagg atgccgacac ggtgatcgcc gtcggcagcg
     5161 gcggcgaacc ggctcccccg gaggtcctcg acaccttgag gaaagccgcg gacagcggcg
     5221 cacgaatcgc ctccctgtgt acgggcgcgt tcgtactggc ccaggccggc ctgctcgacg
     5281 ggcgccgcgc caccacccac tgggggctgg ccggtgacct cgccacccgc ttcccatcga
     5341 tcgatgtcca gcccaacctc cttttcgtcg aggacggcgg catcttcacc tcggcgggcg
     5401 ccgcagccgc catcgacctg tgcctgcatc tggtcaggat cgactacggc gcggcggtcg
     5461 ccaacacggc cgcgcggctc gcagtcgtcc ctcccgtgcg gccgggcgga caggcccagt
     5521 tcatcgagac ccccctgcct cctgagcgcg gcacctcact cgcccccacc cgggcctggg
     5581 cgctcgcgca cctcgatcgc ccactcaccc tggccgagct ggccggtcaa gccaagacga
     5641 gcgtgcggac cctgaccaga cgcttccacg cggagaccgg gctgagcccg ctccagtggc
     5701 tgctgcatcg gcgcatcgac cgggccagag agctgctgga gaccaccgag ctgcccatgg
     5761 atcaggtggc agataagagc ggtctgggca gtgcggattc ccttcgcaag cacatggtcg
     5821 gccgggtcgg gctcactccc cgggcgtatc gtgcgagctt cacccgggtg ccgactggca
     5881 cctcccctga gcccggcaac atgaccagct tgcggtagcg ctccacgtcg gtgatgccac
     5941 gaggatcacg agtagccgca ccttccgcca tgggcgccac cgctggacgc tgagtcggcc
     6001 cacgcgaaga agcggcgggt tcttggcgag gttcgattcc gctgtgagca agcgggcggc
     6061 gagggtggcg gtgccgaagc ttcggggtgc ccagggtgaa tgacgcggtc ggcttcggtt
     6121 agaagtcgaa ttcgccgttt ttggcgccgt ccataaaggc tgcccagacc gacccgctca
     6181 ctacgtatgg cgccaagtcg ggccgctcgg tgtctctgaa ggcgacacgg ccgccgctca
     6241 gagaggccac ctcgatgcag tctccaccat tggcgccgga tttggcggct ttgcgccaga
     6301 tggcggcggc caactcgtca tggacgttca taggtcacca tcttctcgcg tatcgcgtct
     6361 tccgtctcgt tcaccggtcg ggcccatgac cggatcgcgt cgtatctgac actaaccgtc
     6421 cgcaccttgt cttcgcgatc ggtcacctca ccatccgcgg ctgagtccag gtagatggtg
     6481 tctccgcctt tgagcggtga cgcgatgacg aacccgccca gcaggccgat cgtcggtact
     6541 gcggccatcg gaaccacctg caacgtgatg catggatggc tcaacagctt caccagatgc
     6601 tcgagctgtt ccttcatcac ctctggcccg ccgatgggtc tcgagagaac gacctcgtcg
     6661 atgatggctg agtagatggg gggagcggag cgtgtgaaga tcacctgtcg tgccaatcga
     6721 gcctcaagtg cctcgttgac ctgatcctca gtaatgcctg gttgcccctg cagaacagcc
     6781 cgggcatatc ccctggtctg gagaagccca gggatgacca ggggctgcca ggtccgcagg
     6841 gtgcacgcct cgccctcgat cttcggccac tcgcggaacc acgcggggct cgccgtcttg
     6901 gtcaccaagg gccagagccg gatgagctcg cctttgaggc cgagaaacct ctccaccccc
     6961 tccgtgaact cgaggcttgg cgtgctatcc gagggccgct ggggaacgta cgtcaccgcg
     7021 gccggccacc gagtcgtatg ggcggatctg aagacgccac ccgcgttcgt gcatattgcc
     7081 tcgcccacag gctaatggct tatcgccaaa ccagctcatt tcagtgaacg tttacccgcg
     7141 atccgctgcc gtcaggcgta ctcgatgagg atcggctccc cagtgatgtg cagggtttcg
     7201 cccggactcg ggtggtcgac ccggccgtcc aaatggcgta cggagatgac ggcggcgttc
     7261 gcacggatcg ccgcggcgcc ggactgggtc cactggacag ccgcaggatg agcggctgcg
     7321 ccggagccga tggtgaactc gcactgccag gcgttgctgg gtaacccggc tgagagcccg
     7381 tgcccgcagg aacggctctg cgccgaggcg agccagctct gcagcgtctc caccgcgcgg
     7441 gcggctgccg tcggcttccc gccctccgcc tgcagcacga tggggatctt cgtaccgccc
     7501 cagttgtaga agtacatccg ttccaagtga tagttgcggg cgtacatgcc gacgaggaag
     7561 aagcggaccg cgtagttccg tgccatggcc tgatccaacg gctgctgcag cgcgatcgtg
     7621 tacgtcgtcc cggtgttcca caacctgggg tggaccccag cctcatggaa gaggcggtcg
     7681 acggcaccca gtaggtcgag catcgtctcg ggcgggtcgg tcgcggcctg ctggtacagc
     7741 ttgatgcccg cgacgtcaca gtggtcgtat ccgcccagtt cggcgaagcg ttgcagtatt
     7801 tgccggccct cggccgtcca gaggttgccc atcccggggc acacgattgt ggccttcggg
     7861 tcgatcgaac ggatgatcgc gctggcccgc cgggtcatca ctaccagcgt ctccggcgtt
     7921 ccggtgtaca tccgcttgtc gctggccagg acccacaact cgtaggcatt gatccggccg
     7981 cgataccggt gcgccagcgc ccggatgaag cggtcccatt cggcgaggtc gtccggtggg
     8041 gccgagcggg cgccctcggg atagaccgag tgagcgccat cgggcgccgc ccacgccggg
     8101 gtgccgccgg cgacgtacag cgcgggcagg ccggcccgct gcgcgcccgc caccaggctg
     8161 tcgagcgttc gccaatcgaa gacgccgcgt tgcggttcga cttgggacca gcgcgtctcg
     8221 ctgtcccaga accggaccgc cccgaggtcg aagtcgggca tggcgccgct cgaactgttc
     8281 aacgtggccc cgaacagcgt gcgtggcact ggctccggcg gcagcgccca ggccgggccg
     8341 ctgatctgct gctcgatgcc ggggccgccg ctttgcgccg gtgcgggctg cgccggcgag
     8401 cgcagcacga tgacggtcgc ggtcagcacg atggagaaga cgacagccgt cgcggcgagg
     8461 gcacgggcgt gtcggcggat cggtccgggt cgctcggccg gcgcttcggg cgggggcgtc
     8521 tcttctacct ccttgggcgg cgcgggctcc tcttcctcct tgggcggcgc gggctccgcc
     8581 gcctcggatg cgacggccca ctcggcgtac agccggttca tggtggccca gtcggcgccg
     8641 cacgcccgcg cgatgctctc gatcgcgccg aaggtctgtg gtaccgacag gcccacgcag
     8701 tagcggtgca ccgccgactt gctgacgttc gccttacggc cgattgccgc gtagctgtaa
     8761 ccgctgcggt ctttgagctc ggtgaggagc tcaccgagcc gtctctgatg cgcgccgtca
     8821 ctcaccgtgc cagcccttca gaccgcgcca ggaccgtccc agacggccga accgttgcat
     8881 gtcagagccc agatgacatc ccatggtccc ggacgcccgg gacattgtgg cctactcctg
     8941 gccagcgtgc caagcggcaa tgacggcacg tgacaaccca ccgccggaga ggaaccacct
     9001 ggcgtcggtc gtggtcggcg acggtgtgag tcaccgggga catccgtccc atggtcgtac
     9061 gtcggcgcag ctcagaggcc ggttttgctc ccagcgtccc agggacgcgt cggcatgtag
     9121 cgctgggacg agggatctgt gagtctgcac gcatcgggga tggagtggcc ggtacgcgcc
     9181 ggcgctcaaa cgtcatcgcc atacgccaga ccacgagtta ggacatctca tggcatcagg
     9241 caagtcccgg gggctccgcc acatcgcgat cctattcgcg gtggccgtag cggcggtcgg
     9301 cttaccggct cccaccgcgg cgagcgcgga cgacgcgccc agcgcccaag tccaggtcca
     9361 ggtccaggtc cagccgacga tcggagacga cggcaagccg acgaatctcg caccgaagcc
     9421 caccggcctc actccactac agcccacccc caacgcgaca cccagcgtcg aaggttccac
     9481 cgcggcgacg gtccttgtcg agtgttgcgg tctggtcgtc cgctacgaca gcatccagaa
     9541 cctcgtcgtc gcggcgaaca tcaacgccac caacgtcggc aaggggtcga actgcaacat
     9601 ctggaactgg ggcggcggca acgtctggaa tccagtgaac cccggcggga actgtgacac
     9661 cagaagcatg aacggccaca cctacagctg ggcgatctgg tcggacaccg atgcgttcac
     9721 cgtccagtac gaggcgtact ggctgaactt ccatggatcg tggcgcagac tgggcgccaa
     9781 cgtctacacc aagatcaatg gcgcggagac ggcgaagtgc tacagagagt cggatggcgt
     9841 caactgctac gtcgtctact agctggccgg ctgatcagcc cggccacgta gttcagcgtt
     9901 gaacgcgaca aagagcttct ggtgttgacg gtgatggttg tggtgatcaa cccgtccgcc
     9961 aggagctctg ccatgtcatg aggcaaacgc tggtcatcca ttaggggagg cgccagttcg
    10021 ccgtccacag gcgggggccg gtgcggcggt cgaggcggcg gaggaatgac aggacgccgg
    10081 acgcgccggt cgcccaggtg tagccgggct tgtcgaggtc gttgccggtg aagaccggtg
    10141 cggagaactc gccgcccgcg cgcatcagca tcagctcgac gacctcctcg gcgccccgcc
    10201 agtatgcgtc gtcgccggtg gccatcgcca ggtcgatcag tgcttcgccg atgcccgaca
    10261 gaccgcagca ctgggacacg acccacgcct gcggcgcgat ggccaggctc gcgcgggcgc
    10321 cgcgctccgc gagatcgagg tagcggtcct cgccgtacgc ggtggccgcg tgtgccagcg
    10381 ggccgaggat gccggagacg ccctggcacc aggacgcgcc catggccttg gcgtccggtc
    10441 cggtgagctc gccgagcatg gcctcggtgg cggtggccag cgactcgaag cgttccctgg
    10501 ccgcctggcc ggcgtcgggg tcgccggtgg cctcgtggta ggagagcagg aactccgcgc
    10561 agccggcggc gccgtgggcg aaagccatct ccacgttcac ccccgaaccg gcctgggccg
    10621 gtgccaccgc gtccttggag tccgtcacct cgccggagat gagcagtctg gcgcattcgg
    10681 cggctacttc caggtgacgg ggatcctgtt ccagcgcggc cagcgagagg tgccccgcgc
    10741 cgatcccggc gacgccgtgc gcctggtccg cgcgctgttc gcccgccagg acgatcggcc
    10801 cggggtctgg cagctcgggg acggcggtca gtcgcgcggc ggtgaggaac agcgccgttc
    10861 cggtccggcc gaagtagagc gccgggggga gcgcggtggg cggcatgacg cgggccgtcc
    10921 agcgggccag gtcggcggcg acggccttgg cctcggggtg gtgcagcagt tccatgccga
    10981 tcccggccga cccgccgtag acgttcgtga ccggcgggct cgccgtgcgg tccgccgggc
    11041 cgtccatcag gccctcggcg aaacgtacgc acgcgcgggt ggtgtggtcg aggacccgcg
    11101 acagcagatc accgctgaac cgcaccccgt caggccgcga caccgcacgg cccggccgtc
    11161 cggctccggc cctcatgtcg gccgcggccg ccacgcgctc ctcggcgtcg aggctgagca
    11221 ggcggggaac cagcccgatg acgcccgtcg tgacgccggg gaacatccgg gccaggcaca
    11281 tcaccgtccg ttcgacgttc cgggcctggt cggagtcgat catgatgggg ttcatcccgg
    11341 tcgccgcgaa gaacagcgtc gccccgagcg agaagtagtc gtcggcgggc tcggagggac
    11401 gatcctcctg ctggccgggc acgctgtagc cgcggctcca tccgggaagc tgcagcccct
    11461 cgtacctgct gttgccgaag tcgatcagcg tgcaggcgcc gtcctcgccg agcaccacgt
    11521 tcttggggga gaagtccctg acgacgacgc cgcgcgcgtg cacggcgtcc agcacctcca
    11581 gcaaccggcc cgccagcgcg gcgaggtccc tgccgccgct ggtctcggtg aagtcgctgt
    11641 cctcggtgaa gcggccacgc tcgccgacga accggttgag gtccaggctg ccggcgtcgg
    11701 tcatgacgag gaactcgtcg tcgccgtgcc ggaagtggtc gatcggcgtg gggacgcccg
    11761 cgacgccgtc cagggccttg aggatgcgca gctcgttgcg caggtacatg cgcaggtccc
    11821 agccttcggc gttctcgccc acgtaggcgc gggactcctt gaccacgacc ggcctgccgt
    11881 cggcgtcctc ggcccggtag acgttgccgc gcgggccgcg cgcgacgccg gacgtgaggc
    11941 ggtaccggtt gccgatcagc ttggcgggcg tctcgccggt gccctgccca tcggtgctct
    12001 cccgggacgg gccggggacg ctgccctgcg ggcggaacgg gtcggtcgcc cacggcgggc
    12061 agtcgaactc gggtcctgcc gcgcccggca ggtgctcgcc gtcggggccg acaatgatca
    12121 gttcgaagtc gccgttctcg tctacgcggt actggggggc gaagggggcg taccggtaat
    12181 agaccggcgc gtcggggcgc acccggcgat cgctgacgat gcgcggcgcg gccagccccg
    12241 ccagtgcctc ggccagccgg tgaccgaggg ggacgacctc gtccggctgc gggtagacgg
    12301 tgatggcctt gccgaccgcg cccgggtcga ggtctccgga gttgagttcc gcgagcttgt
    12361 cgggcgagcg ggcgaccttg aagtcgcagg acacaccggc caggacgggc aggacccggt
    12421 cgagcgtggc ggccagggtg ccgggacggg cggagacgtg cagcttccag ccctggttgg
    12481 gcgtcgtcgc acgcgggtcg tgaacactga cccaggtgtc gccttcgtag atttccctac
    12541 tattcgactc ggcaaaatgg gtaagagtga caatcacatt tactgtcaac gggaaaaccc
    12601 ttctgcgccg gggcggccgg atgctccaag aaaggccacc ggaagtgcgc cgatggcctt
    12661 tccaccgcgt tacggaacaa gtcgtgcgtc gccgcagacg ccgaacgcgt taccgcgcga
    12721 ttacacgatc gaagggcagc aggggaatgt cgagcacacg gtgcgcttgc aggtgttgac
    12781 gcaggcctgc gggccgtgga gcagcgcggt gagctcgcct tcgaagtcga tggcgaggtc
    12841 ctcgtactcc agagcgcctg cgtcgcgggg ctcaagtgta agaacggaca tgagggctcc
    12901 ttccttggcc accggttggg tggccgatgg tggattcgag cctcgggacg gcaccgggta
    12961 ggtgccgtta cccgcgccct gaccgcgata ggaatcgcct gtcgcggcca aacggacgca
    13021 ttatgtgcat attttcgcaa ccatgtccag gcgcctctca agaagggcca ggccgcatca
    13081 cctccgggac aagtcattta caccagggct ttacgctgac acattggtca cctagattgg
    13141 ctaggtgatc tggtcacccg catgaagtcg ttctggaaga agcgaccccc ggacgttccg
    13201 gcggacaggt cggggctggc ggtcgcctac tgggaaagtc atgacgacga actcttgacg
    13261 gcgagcctgt cgaagatcgc gcgccgcctg ccgtacctgg tgatgtccgc gttgcggatg
    13321 gcatgggagg cccaccgccg cgacacgatc atcgcgctgg ccggaaacct ggcggccggc
    13381 gtcttcaccg tctacggcct ggtcgcgacc tccgacgtgc tcgcctcgct gttcgccggc
    13441 gggccgacgc ccgagcgcat ccgggcggcg ctgccctcgc tggcgctggt cgcggccgcc
    13501 gccgggctgc gcgggacgct gctgaccgcc gccacctggg cccaggcgcg gctcaaggta
    13561 caggtcgaac ggctggccga gacgcggctc ttcgagctga ccacccaggt ggagctgacc
    13621 gcgttcgacg acgacgagtt ccacaacgcg atgcgcagag cccgcgacag cggcgtgccc
    13681 gacgccgcgg gcgtggtcga ggcgacggtc gccgtgatcg gcggagccgt cggcgtgctg
    13741 gcctcggccg tggcgctcgg cctcatgcac ccgctcctga cgccgctgtt gctggtcacg
    13801 gtcgtgcccg cgggctgggc cgcgatacgg gcggcacgcc tgcagtatca ggcgtactac
    13861 cggctgtcgg ccgcgcggcg gcgcaagttc atgctctcgg acctgatggc cgagcggttg
    13921 cccgccgccg aggtgcgcgc gttcgcgctg cgcgacttcc tgctcggcga gtacgggaac
    13981 gtcgccgacc tcgaacagga cgtgcaactc gacgtcgcgc gccgccgtgc agtcaccaag
    14041 gccgccggcg acctgctgac cggcgccgcg accgtcgccg tctacgccgc gctcgccggg
    14101 ctgctggccg tcggcgtcat cccgctcgcg gtggcgggcg cggccgtgct ggccatccgc
    14161 gccggccagc tgtcgcttgc cgggctggtg cagatgatga accggttgta cgaggcgggc
    14221 ctctacttcg gcgactacct gtcgttccgc gcgctggccg cctcgcgcgt acgacagcca
    14281 tccggtacgg cggcgccgga accgtccggg cggctgaccg ccgaccgggt gacgttcagc
    14341 tacccggggg cgagccgccc cgcgctcacc gggatcagcg tctcggtggg gttcggcgag
    14401 gtcatcgccc tggtcggcga gaacggctcc ggcaagacca cgctggccaa gctgctcgcc
    14461 gggctgtacc ggccggactc ggggacgatc cgctgggacg gcgccgacct ggccgacctc
    14521 gacacgcgcg ggctcatctc ggtgatcgcc caggaccaca cccggtggcc gctgaccctg
    14581 cgcgagaaca tcctcatggg ccgcccgctg gacgaagagc gcctggccgc cgccgcggcc
    14641 gccgccgggg cagacgaggt ggtggccggg ctgtcgcaag ggtacgactc gctgctcgac
    14701 cagcgcttcc gcggcggcca cgacctgtcg ggcgggcagt ggcagcggat cgccgtggcc
    14761 cgtggcttct atcgcgacgc cgccctggtg atcttcgacg agccgacctc cgcgctggac
    14821 gcacgcgccg aacacgccct gttcgagcgc atccgcaagc acgccgacgg ccgctccatc
    14881 gtcctcatca cgcaccggct cgccagcgtc cggtacgccg accgcatcta cgtcctcgac
    14941 catgggcggg tggcccagca gggcacgcat gccgagctga tggaaagcgg cggcccctac
    15001 gccgacatgt acaccctcca ggcccaggcc taccgggaag cggtcacatg acctcctggc
    15061 gcgatgttcc cgagagcctc tccgaggtga tccggtgatc attctggcgt cggcctatgc
    15121 ggctctgatc gcggtcctgc tgtacgcggc cgtgagcaag gcgcgtgacc tgccaggatt
    15181 cgccgccgat atcgcgggtt accggctgat cccgcagcgg ctcacgaccg ccgccgccgt
    15241 cacggtggtg ggtgcggagc tggtggcggc cgggctgctc accgcgccgg ccacccggcg
    15301 ctggggcgca ctcctcgcgg cggcgctgtt cgccgccttc ctcgccgcga tggcgtccgt
    15361 gctgcggcgc gggctgagcg tcggctgcgg ctgcttcggc gaccacgacc tcgtcggccc
    15421 cgccaccgtg acccgtaccg gcctgctcgc ggtgctggcg gtcatggccg ccgtcgcggg
    15481 agcttccccg ttcaccttcg tccacctgct ggtgggagcg gcgtacctcg cgctgacctt
    15541 cttgccggtc cggctgatcg gagccgtgga gcgcggtcgc atcggccccc gccccggcac
    15601 ccgctgggac gtgaccccac aggccgcggc cctcaccccg gaaaagctcg gcgtcctgta
    15661 cgcgctgata gggccggcgt gcggcgtctg cagcgccatg ctgcccgcct tcgtcgcggt
    15721 agagcgggtg gacgtcgtcc tggtgagcgc cgcggaggag gggcaggtcc gcgactacct
    15781 cgccgcgcac gaggtcgagt tgcccctggt catcgatccc ggggtgttcg accgtcacgg
    15841 catcccctgg ccgccgtacg ccgtgctgac cgaccggcgg ggcgtcgtcc tggcggcagg
    15901 cggcgtagcc gagcccggcg ctctcgacgc cctgctcggc aacggccttt cagggtgatc
    15961 taaaggtcgg catccagcat agtgatcgcg tccaggacgt cggtcacctc atggtcggcc
    16021 cccggggatc gccccgccga ctggccgcgg tcgatccaga tcgtgcggag acccgcgccc
    16081 cgcccgcccg ccacgtcctt ctccacgtcg tcgcccacca tccagccgcc gtccgccagc
    16141 gtggtgccgc agcgttgggc cgcgatctcg aacagttcgg cagccggttt gctgaagccc
    16201 tcggcgtccg agatggccca gccgtccacc cggtccacca agccgctgtg gtggatcttg
    16261 ccggattggt tgtcggtcat gccgttcgtc acgatgccca ccctccagcc ggacaggcgc
    16321 agccgatcga gggactcgag tacggcgggg cggcaggtga cgaggtgcgg caggcgatcc
    16381 cggtagccgc gccacagcga gtcggccgac tcggcgagcg cgaaccgctc gcggacgtgg
    16441 gtgaagaagg tgctcatcgg cagggagccg tcggcgtcca gctcgatcat ccaggccacg
    16501 tccgccgagc ccagccctct gtcggcggcg aactcggcgg cccagcgccg gaaggcgtcc
    16561 aggcggtcga tcagggtgtt gtcgaggtcg aagagtgcca gcacgcctcg ggatcataca
    16621 gatgttcgat ggcgtgcggc cgtcttctcc agaacaggtg atcacccggt cgtcactcac
    16681 cggccacctt gccggtttat cgtacgcggc atgctgacgc gcagattatt cgcgagtgcc
    16741 ctggccgttc tgaccggtgg tacggtcgcc gtcgtgctgc tccagcccca cgccgccacg
    16801 gccgagcgcc gcggccaggc ccccgtcgtc atcggtcacc gcggtgccag cgcccatcgt
    16861 cccgagcaca cgctgctctc gtacgaggcg gccatagcga tgggcgccga ctacatcgag
    16921 cccgacctgg tctccaccaa ggaccacatc ctggtggcca ggcacgagaa cgacatcacc
    16981 ggcaccaccg acgtggcggc gcatccggag ttcgccgacc ggcgcaccac caagacggtc
    17041 gacgggcggc cgatcaccgg ctggttcacc gaggacttca cgctcgccga gctgaagacg
    17101 ctgcgggcca aagaacgcgt gcccgacctg cggcccgaca acacggcctt cgacggggtg
    17161 gcggagatcc cgacgttcga ggaggtcgtg cggctcgcgc agcgccacgg cgtgggcgtc
    17221 tatcccgaga ccaagcatcc gacgtacttc gactccatcg gcctgtcgct ggaggagccg
    17281 ctgctcgaca tcctgaacgc caaccacgtg cgcaaggcgt acatccagtc gttcgagacc
    17341 gcgaacctgc gggagctgcg taagaagacc aggctgccgc tgatccagct catcacgttc
    17401 ggcggggcgc cgtacgactg ggtcgcggcc ggcgatcagc gtacttatga cgacatggtg
    17461 aagcccgagg ggctgcgcga ggtggcctcg tacgcgagcg ggatcggcgt ggacacccgt
    17521 cgcgtcgtgc cggtgggcgc ggacggcaag ctggtggagc ccaccacgct cgtcgaggac
    17581 gcccaccgca ggcggctgga tgtgcacgtc tggaccatcc gcaacgagaa ctcccagctc
    17641 cccctcgact accggctggg caacccggcc agccccgcct tcccgcgcgc caccggcgac
    17701 gtgatgggct ggctgaccag gctgctcgac ctgggcgtgg acggcgcgtt ctgcgacgac
    17761 ccggcgatgg gccgggccgt cgtcgcgcag cggtcccgat aggcgggagc caggctggag
    17821 aacagggcta cctgagctcg cgcttcagga tcttgcccgt ggcggtcatc ggcagcgcgt
    17881 cgcggaactc cacgacgcgc gggtacttgt aggccgccat gttctccttg gcccaggcga
    17941 tcagctcctc ctcggtcgtg gtcgacccgg cggtgcggat cacgtacgcc ttgatctcct
    18001 cgccgtgcga gtcgtgcggc acgcccacga cggccgccag cgagaccgcc tcgtgcgtca
    18061 tgaggacctc ttcgagctcg cgcgggtaca cgttgaaccc gccgcggatg atcatgtcct
    18121 tggagcggtc gatgatcgag tagtagccgt cggcgtcgcg ggtggcgatg tcgcccgtac
    18181 ggaaccagcc gtcccgcagc acgtcggccg tcgcctcagg gcgcccgtag tagcccttca
    18241 tgatgttgtg gccgcggatc gcgatctcgc cgggcccctc gccctcgatg gtcttccagt
    18301 cgccgtcgat cagcttcatc tcgacgcccc agatcggggt gccgaccgtg cccggcttgg
    18361 tgggccggcc gagctggttg aagctggcca ccggggaggt ctccgacagg ccgtacccct
    18421 ccaggatgtc gaggccgaac gtctgctgga agtccttcag cacctcgacg ggcgaggacg
    18481 ccccgcccgc cacggcgacc cgcagcgtgg tcggtacctc ggcgccctcg gcgtggatct
    18541 tggtgagcat gccccagtac atcgtcggca ccccggcgaa gaacgtgacg ccctccttgc
    18601 gcatgagggc gaccgcctcg cccggctcga agcggggcat cagcacgacg gtggcgccgc
    18661 gcaggaagcc ggtgttcatg acgacggtct ggccgaagga gtggaacagc ggcagcaccg
    18721 ccagataggt gtcgcccccg tcgctgcgcg ggaacatctt gtcgccggcc atggcgttca
    18781 gcagcatgtt ctggtggctg agctcagcgc ccttgggctg gccggtggtg ccggaggtgt
    18841 agaggatcac ggcggtgtcg tcgggggccg tctgcacggt ctcgaactcg ccgggcatgc
    18901 caccgagtgc cgcccagatc gactcgccgt actccgactc ggtcgccagc ggcgtggcgg
    18961 gcagcacgaa gaagtgctcg cagccctcgg acccctcgaa cccggccttg ccccgctcgc
    19021 ccagcggcag ctcgggcgtg ccctcgaagc agaacagcgc cttggcgtcg ctgtcgtcga
    19081 ggtggtaggc gatctcccgc gactgcagca gcacgttgag cggcaccacc gtagccccgg
    19141 ccttgaggat gccgtagtag acgaagggga agtacggcag gttcgggcag gcgagagcga
    19201 ccttgtcgcc cttggcgatg ccacgcgaga cgagcaggtt cgccacctgg ttcgccactg
    19261 tgtcgatcat cgagtacggc agccgcatgt cgccgaagac gagggcggtg ccgtcggggg
    19321 tgttcctggc gctgtcctcc aggacgatcg acaggttgag catgagcgcc ttcctccctg
    19381 tatgcggctt gcggcgccat catcgcagga aggacatacc gaccggtagg tgcaaactac
    19441 ataacctgcg gaactccgct ggacgccgcc caccatgctt gtatggacgc cgtagtccgc
    19501 ctggagtaag caagtaccag attacttacc cctgggaggg gcgcgatgga gtacgactat
    19561 gtgatcgtcg gggccgggtc ggcggggtgc gtcctggcca accggctgtc ggccgatccc
    19621 ggggtgtccg tggcgctggt cgagtcgggc gggcaggacg acaagctgga gatccgcatg
    19681 cccgcgggct tcgccaagct gttcaagacc gactacgact ggaactacac gaccgccaag
    19741 cagagcgaga tgtccggccg ggagctctac tggcccaggg gcagggtgat cggcggctcc
    19801 tcctcgatca acgcgcagat gtgggtgcgc ggctgccagc aggactacga ccagtggggg
    19861 atccccggct ggacgtacga cgacgtcctg ccgtacttca ccaaggccga gcaccgcgtc
    19921 ggcagcaacg gcggcggcgt ctacggctcg acgggcccgc tgttcatctc cgagctgcgc
    19981 agccccaacg tcaccaccgc ggccttcctc aaagcctgcg aagagctcgg attagcacgg
    20041 ctcgacgagc tcaacggccg ctccaacgaa ggcttcagcg ccacgcccgt cacgcagaac
    20101 cgcggccgga ggtggagctc cgccgacgcc tacctgcgcc cggcgctgaa gcggcccaac
    20161 ctgaccgtga tcaccggcgc gaccgtggac cgggtggtgt tcgacggcgc gcgggccgtc
    20221 ggcatcgagc acgacggcgg cgcgcaggtc aaggccaagc gggaggtcat cctgtcggcg
    20281 ggcgcgatcg gctcgccgta cctgctcatg cgctcagggg tcggcgcggc cgacgagttg
    20341 cgcgacgcgg gcgtcacgat cgtgcgagac ctgccggaag tcggcaagaa cctgcaggac
    20401 cacctgtcga ccggcgtgta cgtgcagtcc aagcagccgg tcacgctgac caaggcggag
    20461 tcgatcggca acctgctccg ctacatcgtg ctgcgctccg gcatgctcac cacgaacgtg
    20521 ggtgaggcgg tggcgttcat caggacctcg ccggaggagc ccgcccccga catcgagctg
    20581 atcttcgcgc ccggcccgtt catcgaccac ggcctcacgc cgccgaccgg ccacggactg
    20641 accgtcggcg tggtactgct gcagccggag agccgcggcc ggatcgggct gaacggccgc
    20701 gaggtggtga tcgaccccgg ctacctgagc aaggaggccg acgtcaagcg gctcatcgcc
    20761 gggctgaaga cggccaagca ggtcttcgcc accgccgcga tgaaggagta cgcgggcggg
    20821 ccgatggccc cctacacggg cccggagagc gacgccgacc tcgcccagtg gatccgcgag
    20881 cgcggcgaga ccctctacca cccggtcggc acctgccgca tgggcaccga cgcggagtcg
    20941 gtcgtcgacc cgtcgctcaa ggtacgcggc ctcgacgggc tcagggtcgt ggacgtgtcg
    21001 atcatgccga ccctcaaccg cgggcacacg cacgccccgg ccatcatgat cggcgagaag
    21061 ggggccgagc tcatcgccaa gcgctcttga cgtaagtgag cgcttgcaga aggcttggtt
    21121 catgacgatc tccagtgacc tggacatctc gcagctcatg ttctgggggc tgccccaggc
    21181 cgagcgcatg gccgtcttcc gccggttgcg gcagctcgac cagccggtgt tcctggcgga
    21241 gcaggctgtg ccgttcatca agggcggccc cggctactac gccctcgtgc gccacgcgga
    21301 cgtgtccgag gccagcagga acgcggcggt gttcagcagc gagccgtgct cgaacagcgt
    21361 gccggacatg ccccgctggc tggccgtgta cttcgggtcg atgatcaaca tggacgaccc
    21421 gcggcacgcg cggctgcgca ggatcgtgtc ccgggcgttc accccgcgca tcctgtccaa
    21481 gatggaagag gacctggcca cggccgccgc cgagatcgtg gaccaggcga tcgaggaggg
    21541 tccgggcgac ttcgtggcgc agatcgccgc ccggctcccc gtccgcgtca tctgcgacat
    21601 gatggggatc ccggcgacat ttcatgacat ggtgcttcgc cggaccaacg tgatcctcgg
    21661 caacgccgac cccgagtaca ccggcatcga ccccgagttc agccgcgtca acgtggcccg
    21721 cggcctggcc aagctgctgc acgcgggctt ctccctgaac cggctcgccg cccgcctggg
    21781 cgacgagcgg cgcaggcatc ccacgggcga cctggtcagc ctgctggtca acggcgagga
    21841 gcggctcacc tcgcaggagc tgggctcgtt cttcatcctg ctcgtggtgg ccggcagtga
    21901 gacgacccgg aacgcgatcg cctacgggct caagctcttc accgaccacc cggaccagcg
    21961 ggagctgctc ctggacgact tcgacggccg cgtcaccaag gcgtgcgacg agatcgtgcg
    22021 ctactccacg ccggtgatcc agttccgccg cacgctcacc cgggaccacg agatgaacgg
    22081 catgagctac aagaagggcg acaaggtgct gctcttctac aactcggcca accgcgacga
    22141 gacggtgttc cgggaccctg acgcgttcga catcactcgc gatccgaacc cgcacgtcgg
    22201 cttcggcggc ccgggcccgc actactgcct gggcgcccac ctggcgcgca gggagatgac
    22261 cgtgatgttc cgcgagctgt tcacccgcct gccgggcatc aggtcggagg gggagcccga
    22321 cttcctgctg tccaacttca tcaacgggat caagcacctg aagtacacct tctgagcgcc
    22381 tcggcgagcc cttcctcgcc gcgccaggcc acgaacccgt ccggtcgtac gagcagtgtc
    22441 ccgtacggcc agccgtcgac cacgtgcacc ggcacgtcga gcccggtcac cggctccgcg
    22501 gcgaacacgc agaacgtcga gccgaccagg tcgagcgtgg agcgctcgcc gacccagacg
    22561 tgcggcagcc gcgagcc
//
