LOCUS       NZ_JAHFZZ010000002     20657 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Nonomuraea sp. NEAU-A123 Scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZZ010000002
VERSION     NZ_JAHFZZ010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nonomuraea sp. NEAU-A123
  ORGANISM  Nonomuraea sp. NEAU-A123
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 876732)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Nonomuraea triticisoli sp. nov., a novel actinobacterium isolated
            from rhizospheric soil of wheat in Langfang, Hebei Province, China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 876732)
  AUTHORS   Zhang,L. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, Changjiang Road No. 600, Xiangfang
            District, Harbin, Heilongjiang Province 150036, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603905.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 04:26:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,983
            CDSs (total)                      :: 11,901
            Genes (coding)                    :: 11,761
            CDSs (with protein)               :: 11,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 5, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 2, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 28 of 140
            Pseudo Genes (incomplete)         :: 121 of 140
            Pseudo Genes (internal stop)      :: 3 of 140
            Pseudo Genes (multiple problems)  :: 12 of 140
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:52:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 856075
            Orig. end                         :: 876732
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZZ010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20657
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:11029](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(313..933)
                     /locus_tag="KLK06_RS08060"
                     /old_locus_tag="KLK06_08060"
     CDS             complement(313..933)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017556399.1"
                     /locus_tag="KLK06_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08060"
                     /product="VOC family protein"
                     /protein_id="WP_214634651.1"
                     /transl_table=11
                     /translation="MTEPQLDHLVYAVPDLAAGVAEFAERTGVRPVAGGSHPGGTANHL
                     VRFGPGSYLEIIGPDPEASVRPRAFGLETLTEPRLAAWAVRPHDLDKAVRQAREQDYDP
                     GDVHPLSRRTPAGELLEWRLTRRADPAAVRPVPFLIDWGATPHPADSDLPLVGLTSFSA
                     VHPAPDALRRDLAALGVRLDISQGPEAVLRAVIDTPLGPVTLR"
     gene            complement(930..1091)
                     /locus_tag="KLK06_RS08065"
                     /old_locus_tag="KLK06_08065"
     CDS             complement(930..1091)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_08065"
                     /product="hypothetical protein"
                     /protein_id="WP_214634652.1"
                     /transl_table=11
                     /translation="MKGQCPHNQITDKLTWQNPQMLEIEPWIATRWDHPRRRVLHALGL
                     RTTVKADQ"
     misc_feature    complement(1141..1155)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.89"
                     /tool="antismash"
     misc_feature    1142..1155
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.37"
                     /tool="antismash"
     gene            complement(1145..2311)
                     /locus_tag="KLK06_RS08070"
                     /old_locus_tag="KLK06_08070"
     CDS             complement(1145..2311)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020539720.1"
                     /locus_tag="KLK06_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08070"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_214634653.1"
                     /transl_table=11
                     /translation="MTLHLAVALDGAGWHPAAWRESPADVFSARHWAGLVAEAEQGLLD
                     FVTIEDALGLQSTLPDAPDDRNDQVRGRFDAVLLAARLAPLTSRIGLVPTATTTHTEPF
                     HVAIGIATLDHVSQGRAGWRPQISPRASEARHFGRREFPPLDLVLNRPGGVDLSGDPHV
                     RDLFAEAADAVEVARRLWDSWEDDAEIRDLATGRFIDRDKLHYADFAGRFFSVKGPSIT
                     PRPPQGQPVVTALAHARLPYEFAASSADIVYVTPHSAEQARDIVEEIRGLSAELKIFAD
                     LVVFLGEDAARRKARLDELDGAELVSDAAIFTGTVRELADLLLEWRRAGIQGFRLRPGA
                     LPYDLAQIARGLTVELRERGVFRHEYEAATLRGLLGLPRPASRYADLS"
     gene            complement(2308..3627)
                     /locus_tag="KLK06_RS08075"
                     /old_locus_tag="KLK06_08075"
     CDS             complement(2308..3627)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658221.1"
                     /locus_tag="KLK06_RS08075"
                     /note="This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN; Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08075"
                     /product="NtaA/DmoA family FMN-dependent monooxygenase"
                     /protein_id="WP_214634654.1"
                     /transl_table=11
                     /translation="MTRKQVHLAAHFPGVNNTTVWTDPRSGSQIDFASFVHLARTAERG
                     KLDFFFLAEGLRLRELKGRIHDLDVAGRPEALTVLGALAAVTDRLGLAGTVNATFNEPY
                     ELARRLSTLDHLSEGRAGWNVVTTSDAFTGENFRRGGFLNRADRYKRAGEFLRLARELW
                     DSWHPDAIAADPETGTFVRPGAIGTVEHSGEHFTVQGRFTLPRSPQGRPVIIQAGDSDE
                     GREFAAANADVIFTPHGKLEDGKRFYADVKRRLAKYGREPHQLKIMPGVTFALGDTEED
                     AAENAAYIRCQQVGPQTATAFLEQVWGRDMSAYDPEGPLPDVEPDLSEGVSQGRVPIKD
                     RGDVAAKWRALAEEKGLSIRELVIEVTGRQTFIGTPETVARLIDEHVQADAADGFILVP
                     HLTPGGLDEFVDRVVPLLQERGAFRTDYTGTTLRDHLELS"
     gene            complement(3624..4535)
                     /locus_tag="KLK06_RS08080"
                     /old_locus_tag="KLK06_08080"
     CDS             complement(3624..4535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889105.1"
                     /locus_tag="KLK06_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08080"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_308168145.1"
                     /transl_table=11
                     /translation="MSISTQTAVYATPVDHVTYGHYGPGRLHLSPDWNRPVYPFQGRVT
                     ADGSSGFRAEPGRYHLYVAWVCPYAHRAAIVRKLKGLEDVVTLSYVDDERDGRGWAFRK
                     RRGHDPVNGFTLLEQGYEATEKGYGGHISVPVLWDRRTGAIVSNNFPDITIDLATQFEQ
                     WADTSVDLYPDELRPEINKLNGWIYFDVNAGVSRVARAASEDEREQERHRVVSALERLD
                     ERLAERRFLTGDTITEADVRLWVTLARFDSGDNRGHLISERELSDFEHLWPYARDLYQR
                     PAFRETTEGLPATWDASHGRGI"
     gene            complement(4550..5062)
                     /locus_tag="KLK06_RS08085"
                     /old_locus_tag="KLK06_08085"
     CDS             complement(4550..5062)
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850851.1"
                     /locus_tag="KLK06_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08085"
                     /product="flavin reductase family protein"
                     /protein_id="WP_214634655.1"
                     /transl_table=11
                     /translation="MTDTLPDRAVAADQFKRALAVHASGVVIITAQSDGIPVGLTATSF
                     SSVSLEPPLVSFYVDRSSTTWPQLSGADHFAVNILTSDQADLAARFARKSIDRFAAPTR
                     WRPGPLGAPLLQDVSAHLVCLPYERAVVGDHILVVGLVAEADVQRPGRPLLYHQGRFGR
                     FLAHPDS"
     misc_feature    5068..5084
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.15"
                     /tool="antismash"
     gene            complement(5462..6040)
                     /locus_tag="KLK06_RS62245"
                     /old_locus_tag="KLK06_08090"
     CDS             complement(5462..6040)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="KLK06_RS62245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08090"
                     /product="response regulator transcription factor"
                     /protein_id="WP_214634656.1"
                     /transl_table=11
                     /translation="MEVGEGGEGSLPSESGGHRFQELMLKGGRKERPGKAADDDVGAVD
                     AAFAEQARQPARASMEQALALAEPDRLIFPFAMTGAWQLLKALRGTSHTALVADILGAV
                     HDGAPAKAEHPPGLKLSPSELRVLRYLPTNLTRLEIASELPVSLHTINTHIRRIYAKLG
                     ATDRSSAVQRGRDLRLLSPTQSHRQGAHG"
     gene            6499..6684
                     /locus_tag="KLK06_RS08095"
                     /old_locus_tag="KLK06_08095"
     CDS             6499..6684
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLK06_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLK06_08095"
                     /product="hypothetical protein"
                     /protein_id="WP_214634657.1"
                     /transl_table=11
                     /translation="MLERLLVAAAVVASAIIGPMALTTPSASAAHTPSTAIAAQAAATM
                     AQDPVPGDEDDEDRAR"
     gene            <6964..7272
                     /locus_tag="KLK06_RS08100"
                     /old_locus_tag="KLK06_08100"
                     /pseudo=""
     CDS             <6964..7272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580967.1"
                     /locus_tag="KLK06_RS08100"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08100"
                     /product="TetR/AcrR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="AFLTASTDPDVQQIMLIDAPAVLGWSEWRAMDEGASAHHLAEALT
                     TLIEQGTIAPQPVEPLTHLLSGAMNEAALWLATSTNPNDLADTWAALSRMLEALRHK"
     gene            complement(7396..8283)
                     /locus_tag="KLK06_RS08105"
                     /old_locus_tag="KLK06_08105"
     CDS             complement(7396..8283)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="KLK06_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08105"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_214634658.1"
                     /transl_table=11
                     /translation="MDVDLRKLRYFVAVAERLHFGRAAEALHIAQPVLSRQIRALEDEF
                     KVQLFVRTRRATELTSAGEQLLADAGPLLASAEALRRRVSRAARGADIFTVGFMPGLIV
                     TPAVRALRERHPGLTVEVVRTTWEDQTETIHDGRVDIGYVRLPIDQRGLRVRPLMSEPR
                     VAVLPAGHHLAGKDMIGIADLTDEHLLQDPDAVPEWRDIATELRRPGRRRPAPVFHAVE
                     EKLEHVAAGHGVVVLPLSVVAFYTRPDVTYVPVTDIPPNQVCLAWDSARRNPLIGEFAA
                     IATDLGADGPSPAL"
     misc_feature    8354..8367
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            8407..9126
                     /locus_tag="KLK06_RS08110"
                     /old_locus_tag="KLK06_08110"
     CDS             8407..9126
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="KLK06_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08110"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_214634659.1"
                     /transl_table=11
                     /translation="MDLQGQRVVVLGGTSGIGLATAEAAARQGAVVTVASSRRASVDHA
                     LTRLPDRCDGRVVNLTDARAVGRLFDDLGEFAHLVYTAGEPLTLMPLDTLDLDAAGHLF
                     ALRYFGALGAVRAALPYLRKDGSITLTTGIAKDRPGPGWAVAASICGAMEALTKALAVE
                     LAPIRVNVVSPGFIRSPLWSGMGDEERERMYTELAAAIPVGRVGEVEDIARAYVFLMTE
                     PFATGTVLTVDGGHVLV"
     misc_feature    complement(9384..9402)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.08"
                     /tool="antismash"
     gene            9450..10004
                     /locus_tag="KLK06_RS08115"
                     /old_locus_tag="KLK06_08115"
     CDS             9450..10004
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024600.5"
                     /locus_tag="KLK06_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08115"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_214634660.1"
                     /transl_table=11
                     /translation="MATDLQVLKIDRSFTYIDVDGNGVITRDDLQGLGARLLAGFGASP
                     AGTQGRRVADSFDSLWDTIADAADLNHDSRITPDEYRSSLIASFIDGDRFEPIFRPAID
                     AVLAVADTDGDGLIQPEEFQLIHEAFGRSEQDSEQAFAALDLDGDGALSRGELLHAARD
                     YYTSADPSAIGNLLFGSLPTP"
     gene            10001..11029
                     /locus_tag="KLK06_RS08120"
                     /old_locus_tag="KLK06_08120"
     CDS             10001..11029
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="KLK06_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08120"
                     /product="terpene synthase family protein"
                     /protein_id="WP_214634661.1"
                     /sec_met_domain="T1TS (E-value: 2.1e-46, bitscore: 154.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALADARPHLRPLLQRVPALRGRCRMHPRVDAAGQQVLCWARQA
                     GLADDPKASRRLHAIDGHRMAGRVFTDSSDDKLVQFSQWLTWVVLLDDHWDERSCPTPQ
                     EIDHTYTRLLHVVDHDREPAHADPMERAFTQLWQVTSADMSPAWRGRFRAHLELNRQST
                     HWEIRTRRTGQFSPLADYPRHRRVASASFIFDAGEAVLGTELPASLACLPAWSDLADAA
                     NDVAVWCNDVLTLDKDEHEADLSNYVLAAQHHLGLSPAAAISWVIDRIAARTTDLRRAA
                     RALPAVYRRLDLSHGSARAASKVACAYLALPHATLEWTCEAARYRPLSSSTSQAGAWPA
                     RE"
     gene            complement(11311..12303)
                     /locus_tag="KLK06_RS08125"
                     /old_locus_tag="KLK06_08125"
     CDS             complement(11311..12303)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019474.5"
                     /locus_tag="KLK06_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08125"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_214634662.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.5e-15, bitscore:
                     52.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTMRLIMALAALSGRPIRLSSVAAPDDDPDSIRLHVESADQIKP
                     GRSARAYRGIVYAAPARKLRMDILTPQAPGPYPLVLYLPGGGFVTARRAMAARQRHCVA
                     QAGFAVASIDYRTVRDGATYLDGLADVAAALSFLRLHADHYGINPARTALWGESAGGYL
                     AAMAATDPGSGVAAVTGSGVDAVIDVFGASHLATIADGFDPATVTAYTTTGAALPTYLL
                     GPGRAFADHPAEVINADPASHITSETPPFLLLHGSDDRIVTPAQTARLHQALRRADVDS
                     TRYVLQGAGHGALSSAPRIWTSTQVMAIIVNFLRSRLGVTPESDNKAST"
     gene            complement(12300..13502)
                     /locus_tag="KLK06_RS08130"
                     /old_locus_tag="KLK06_08130"
     CDS             complement(12300..13502)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00710.1"
                     /locus_tag="KLK06_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08130"
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_214634663.1"
                     /transl_table=11
                     /translation="MIETTALRRPILLLGILGLLTAVAPLAIDMYVPGFPELGRELAAG
                     EPTVQMSMSAFLIGLVAGQLVIGPLSDGLGRRRLLVTGTAAFALLSACCALMPTAPLLV
                     AGRFLQGCAGAAGLVLARAVLTDRFAGPRLPVYFSILAMILGVAPVLGPLLGGMIVTAY
                     GWRAVFWALTALGLVMLAATLLGVPESLPPARRSPGGLRPAFASMAALLRQRAFTGYTL
                     TLGLAAGAMFVYIGGSSYVFQNGFGLSAVQYGLVFSVNAAAMLVASAGFGLTARRVALP
                     ALLSGYLAIGTLGALALVIQATLAPTLAGTWLCLAVMLFGIGGIFPAVTTITQTIGHAR
                     AGAASALSGAAAYLFGALAAPLSGATLRAMALVMLAAMALAVLALLAARPWRPLPERSF
                     A"
     gene            13558..14043
                     /locus_tag="KLK06_RS08135"
                     /old_locus_tag="KLK06_08135"
     CDS             13558..14043
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013231.5"
                     /locus_tag="KLK06_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08135"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_214634664.1"
                     /transl_table=11
                     /translation="MSRSTDRVRELWAAARPDLDTSPMEVIGPLKRVIALLGEALDPLY
                     VDAALTGTELDVCLRLRHDPSPTIARRLADQMRHSRAAISKTLTRLESRGLVVREPSPA
                     DRRASLVRLTPAGEAAVDAIFPRQLAREAELLEGLGADRERVIEALNLLADVLGKRM"
     gene            complement(14245..14622)
                     /locus_tag="KLK06_RS08140"
                     /old_locus_tag="KLK06_08140"
     CDS             complement(14245..14622)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017567760.1"
                     /locus_tag="KLK06_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08140"
                     /product="DUF427 domain-containing protein"
                     /protein_id="WP_214634665.1"
                     /transl_table=11
                     /translation="MTTREPKIPGADHPITIEKTGQRVVARVGERVVADTTRALTLREA
                     NYPPVQYIPLGDVDQTLLAATDTRTYCPYKGDASYYSIALAEGGLADAVWSYREPYDAV
                     VDIADHVAFYTDRVEVVVGAS"
     misc_feature    14650..14664
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    14942..14960
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.94"
                     /tool="antismash"
     gene            14996..15715
                     /locus_tag="KLK06_RS08145"
                     /old_locus_tag="KLK06_08145"
     CDS             14996..15715
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (5-170). E-value: 4.1e-16. Score:
                     51.4. Matches aSDomain:
                     nrpspksdomains_KLK06_RS08145_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="KLK06_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08145"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_214634666.1"
                     /sec_met_domain="adh_short (E-value: 5.9e-36, bitscore:
                     119.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.5e-31, bitscore:
                     105.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEMRTALVTGATSGIGRAAALKLAQDGFRVLVHGRDAERGAAVV
                     KEIESAGGSAEFLAADLTDVRAIRQLAAVAGDVDVLVNNAGFAWFGPTADLDPDRYDEL
                     FDANVRSAYYLTAAIAPKMAERGRGTVINLGSMAGQIGLAGGAAYSATKAALTSLTRSW
                     AAEYSPQGVRVNTIAPGPAYTGGSSRESLTALGKTTLLSRTAEAEEIGDVIAFLASPAA
                     GYITGAVIPVDGGRTAV"
     aSDomain        15011..15505
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLK06_RS08145_PKS_KR.1"
                     /evalue="4.10E-16"
                     /label="KLK06_RS08145_PKS_KR.1"
                     /locus_tag="KLK06_RS08145"
                     /protein_end="170"
                     /protein_start="5"
                     /score="51.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGATSGIGRAAALKLAQDGFRVLVHGRDAERGAAVVKEIES
                     AGGSAEFLAADLTDVRAIRQLAAVAGDVDVLVNNAGFAWFGPTADLDPDRYDELFDANV
                     RSAYYLTAAIAPKMAERGRGTVINLGSMAGQIGLAGGAAYSATKAALTSLTRSWAAEYS
                     PQ"
     CDS_motif       15017..15091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KLK06_RS08145_0001"
                     /evalue="4.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="KLK06_RS08145"
                     /protein_end="32"
                     /protein_start="7"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LVTGATSGIGRAAALKLAQDGFRVL"
     gene            15981..16592
                     /locus_tag="KLK06_RS61350"
                     /old_locus_tag="KLK06_08150"
     CDS             15981..16592
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634312.1"
                     /locus_tag="KLK06_RS61350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08150"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_214634667.1"
                     /transl_table=11
                     /translation="MPSKVNASKPSARERLLAAADDLFYREGVQTVGIDRIVQKAGVAK
                     ASLYNLFGSKDELVQAYLDARHADTREQVERTLTRFRTPRERLLGVFDAQGQLFTEPDF
                     NGCAHMTASAEARPGSPIECAAERYRLWVRTLFTDLAREAGVADFEGLARQLHLLYDGA
                     GVSARMDQDPSAATTARAAAAALFDAAVRDGDASARIPRG"
     gene            complement(16688..17326)
                     /locus_tag="KLK06_RS08155"
                     /old_locus_tag="KLK06_08155"
     CDS             complement(16688..17326)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889918.1"
                     /locus_tag="KLK06_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08155"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_214634668.1"
                     /transl_table=11
                     /translation="MKLTIFGATGGTGTELLRQALAAGHEVTAVVRDPRRLPADLPSGL
                     DIFQADLMDPDAIAPAVKDRDAVLSAMGSRDRAPTTVCADSISAIATAMERGRTRRLLM
                     TSASGLVADAGDGVLVRYVVKPLIVQRLFKHSYADLREAERRLRATNLDWTIVRPSRLT
                     DGAPTGRYRTAWDTNLRGGLSTTRADVAHCLLALAADPASVRHAVSVAS"
     gene            complement(17464..18078)
                     /locus_tag="KLK06_RS08160"
                     /old_locus_tag="KLK06_08160"
     CDS             complement(17464..18078)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895134.1"
                     /locus_tag="KLK06_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08160"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_250904980.1"
                     /transl_table=11
                     /translation="MMADRKQSRPPTGTAVRSADWDGRDLTQETYHQVLFVDVDMTELT
                     NSGSVFEECTFSDVRFNVSVHEDAMFLNCTFSRCSFFDATFKACKMTGSMFDGCSYGLL
                     KVEGGDWSFTGLPGADLRGSAFHGVRLREADLTGARLEKAEVLRCDLSGAWLNGADLTG
                     CDLRGSDLSDLDPSTVTLKKAIIDSFQATVVATALGFDVRA"
     misc_feature    complement(17638..17640)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18075..18317)
                     /locus_tag="KLK06_RS08165"
                     /old_locus_tag="KLK06_08165"
     CDS             complement(18075..18317)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016001.5"
                     /locus_tag="KLK06_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08165"
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_214634669.1"
                     /transl_table=11
                     /translation="MEAREITDSLARNLNLATDPAVHLQVSADHFSRRAHTADGAERER
                     LSESMLRIFPTYSGMQRKTQRELPVVVIERTEVAG"
     gene            complement(18771..19928)
                     /locus_tag="KLK06_RS08170"
                     /old_locus_tag="KLK06_08170"
     CDS             complement(18771..19928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851709.1"
                     /locus_tag="KLK06_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLK06_08170"
                     /product="phosphatidylinositol-specific phospholipase
                     C1-like protein"
                     /protein_id="WP_214634670.1"
                     /transl_table=11
                     /translation="MRRAPALIAAGLLAATTAATVVHAVPAAATAAAAGRGPLRINHIQ
                     TMATHNSYHRELTDAEKDVQRKTDANWWNLQFSHPALPRQFQDQHVRGIELDVFPDPKG
                     GLYTAPLVRRDAGLPPLTDPALREPGFKVLHWADHDYGTNCSTLVTCLRQVREWSDAHP
                     GHVPLTILTELKSTDPAKEALGGAKSPKWDTTLLDALDAEIHSVFPADRLITPDNVRRP
                     GKTLEQSVLQYGWPELSSSRGKVMFFMDNQATEIQTPYLTGRPSLEGRVLFTNSRPGHA
                     DAAFVGWNEPQGDNTAQIQDLVRRGYYVRTRSDVPFVEARSGDTSRLRAALDSGAQMVS
                     TDFPVVGLSARHGSDYTAELPGGGVARCNPVNAPTGCRDQSLEKH"
     misc_feature    complement(20332..20344)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    20513..20528
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    complement(20515..20528)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.44"
                     /tool="antismash"
     misc_feature    complement(20516..20531)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 tcgagcgcgt cgatcggcac cgccagttcg gccgccttga tgaggaagat gtgggtgacg
       61 caactgccga gcacaccggc ctggagttcg ggggaggtgg ggccgaggtc gtagccggcg
      121 aagtcggggc cgctgtcgct gatgatctgg aagtcccgga tcctgacgcg ccggattccg
      181 ctgcggccct cggcggtgac gtgggcgtgc agcgggaccg gcccggcggc gggcgcctcc
      241 cggcgggcca gcagggccgt gcgcttgtgc gacaggtact cgcgtagggt gctcatggtc
      301 ttctcttcct ggtcagcgca gggtcacggg gccgagtgga gtgtcgatca cggcgcgcag
      361 caccgcttcg ggtccttgtg agatgtcgag ccggacgccg agagcggcca ggtcgcgccg
      421 cagcgcgtcc ggggccgggt gtacggcgga gaaggaggtc aggcccacca ggggcaggtc
      481 cgagtccgcg gggtgggggg tggcgcccca gtcgatgagg aacggcaccg gcctgaccgc
      541 cgccgggtcc gcacgccggg tgagccgcca ctccagcagc tcgcctgccg gggtgcgtct
      601 ggacaggggg tgtacgtcgc cggggtcgta gtcctgctcg cgggcctgcc gcaccgcctt
      661 gtccaagtcg tgcgggcgta cggcccaggc ggcgagccgc ggctcggtga gagtttccag
      721 gccgaaggcc cgcggccgta cggacgcctc ggggtcgggc ccgatgatct ccaggtagga
      781 gccggggccg aaccggacga ggtgattggc ggtgcctcca ggatggctgc ctccggccac
      841 cgggcggact ccggttcgct cggcgaactc ggcgactccc gcggcgaggt cgggcaccgc
      901 gtaaacgagg tggtcgagct gtggttctgt cactggtccg ccttcacggt ggttcgcagg
      961 ccgagagcat gaagaacgcg gcggcgtgga tggtcccacc tcgtggcgat ccacggctcg
     1021 atctccagca tctgcgggtt ctgccaggtc agcttgtcgg tgatctggtt atgagggcac
     1081 tgccctttca tcaacgcttg cgactcaaag ccactataac ctacctaaat agtagagaat
     1141 aatttcacga caaatccgcg tagcggctgg ccgggcgtgg caggccgagc agcccgcgca
     1201 gggtggcggc ctcgtactcg tgccggaaca ccccgcgttc ccgcagctcg accgtaaggc
     1261 cgcgggcgat ctgcgccagg tcgtacggca gtgcgcccgg ccgcagccgg aatccctgga
     1321 tgcccgcccg ccgccattcc agcagcaggt cggcgagttc ccggacggtg ccggtgaaga
     1381 tcgcggcgtc ggagacgagt tcggccccgt ccagttcgtc caggcgcgcc ttgcgccggg
     1441 ccgcgtcctc ccccaggaag acgaccaggt cggcgaagat cttcagctcc gcggacagcc
     1501 ctcggatctc ctcgacgatg tcgcgcgcct gctcggccga gtgcggcgtg acgtacacga
     1561 tgtcggcact gctcgcggcg aactcgtacg gcagccgcgc gtgcgccagc gcggtcacga
     1621 ccggctgccc ctgcggcggg cgcggcgtga tcgacgggcc cttcaccgag aagaaccgcc
     1681 cagcgaagtc ggcgtagtgg agcttgtccc gatcgatgaa ccggccggtg gccaggtcgc
     1741 ggatctcggc gtcgtcctcc cagctgtccc agagccgccg cgccacctca accgcgtcgg
     1801 cggcctcggc gaacaggtcg cgcacgtgcg gatctccgga caggtccacg ccgcccggcc
     1861 ggttcaggac caggtccagg ggtgggaact ccctacggcc gaagtgccgc gcctcggagg
     1921 cgcgcgggga gatctgcggc cgccaaccgg cccggccctg gctgacgtgg tcaagggtgg
     1981 cgatgccgat ggccacgtgg aagggctcgg tgtgcgtggt ggtggccgtc ggcaccagac
     2041 cgatccggct ggtgagcggg gccagccggg ccgcgagcag cacggcgtcg aagcggcccc
     2101 gcacctggtc gttccggtcg tcgggcgcgt cgggcagagt ggactgcagg ccgagcgcgt
     2161 cctcgatggt gacgaagtcg agcagccctt gctcggcctc ggccacgagt cccgcccagt
     2221 ggcgggcgga aaagacgtcc gccggggact cgcgccaggc ggcggggtgc cagcccgcgc
     2281 cgtccagggc cacggccagg tgcaacgtca tgagagctcc agatggtcac ggagggtggt
     2341 gccggtgtag tcggtacgga aggcgccgcg ctcctgcagc agcggcacca cccggtccac
     2401 gaactcgtcc agcccgccgg gcgtcaggtg agggacgagg atgaacccgt cggcggcgtc
     2461 agcctgcacg tgctcgtcga tgagccgggc cacggtctcg ggggtgccga tgaacgtctg
     2521 ccgccccgtc acctcgatga ccagctcgcg gatcgacagc cccttctcct cggccagtgc
     2581 ccgccacttg gcggccacgt ccccgcggtc cttgatcggc acccgtccct gggagacgcc
     2641 ttccgacagg tccggctcga cgtccggcag tgggccttcc gggtcgtagg ccgacatgtc
     2701 acgaccccac acctgctcca ggaacgcggt cgcggtctgc ggcccgacct gctggcagcg
     2761 gatgtaggcg gcgttctcgg ccgcgtcctc ctcggtgtca cccagcgcga acgtcacgcc
     2821 gggcatgatc ttgagctggt ggggctcgcg gccgtacttg gccaggcggc gtttgacgtc
     2881 ggcgtagaag cgcttgccgt cctccagctt gccgtgcggg gtgaagatca cgtcggcgtt
     2941 ggcggcggcg aactcgcggc cctcgtcgga gtcgcccgcc tggatgatca cggggcgtcc
     3001 ctgcgggcta cgcggcaggg tgaaccggcc ctggaccgtg aagtgctcgc cggagtgctc
     3061 gaccgttcca atagcgcccg gccggacgaa ggtgccggtc tcggggtcgg cggcgatcgc
     3121 gtccgggtgc caagagtccc acagctcgcg cgccaggcgg aggaactcgc ccgccctctt
     3181 gtaccggtcg gcgcggttga ggaaaccgcc gcggcggaag ttctcgccgg tgaaggcgtc
     3241 ggaggtggtc accacgttcc acccggcccg gccctcgctc agatggtcca gcgtggacag
     3301 gcgcctggcc agctcgtacg gctcgttgaa ggtggcgttg acggtcccgg cgagcccgag
     3361 ccggtcggtc accgcggcca gggcgccgag cacggtgagc gcctccggcc ggccggccac
     3421 atcgaggtcg tggatgcggc ccttgagctc gcgcagccgc agcccctcgg ccaggaagaa
     3481 gaagtcgagc ttgccccgct cggccgtcct ggccagatgg acgaacgagg cgaagtcgat
     3541 ctggctgccg gagcggggat cggtccagac cgtggtgttg ttcacgccgg ggaagtgggc
     3601 ggccaagtgg acctgcttgc gcgtcatatc ccccgcccgt gcgatgcgtc ccacgtcgcc
     3661 ggcaggccct cggtcgtctc ccggaaggcg gggcgctggt agagatcgcg ggcgtacggc
     3721 caaaggtgtt cgaagtcgga aagctcccgc tcgctgatga gatggccgcg gttgtcaccg
     3781 gagtcgaacc tggccagcgt cacccacagc cgcacgtccg cctcggtgat cgtgtcgccg
     3841 gtcaggaacc gccgctcggc cagacgttcg tccagccgct ccagcgcgga gacgacccgg
     3901 tggcgctcct gctcgcgctc gtcctcggaa gcggcgcggg ccacacggga gactccggcg
     3961 ttgacgtcga agtagatcca cccgttcagc ttgttgatct ccgggcgcag ctcgtcgggg
     4021 tagaggtcga cggaggtgtc ggcccactgt tcgaactggg tggccaggtc gatcgtgatg
     4081 tcggggaagt tgttgctgac gatcgcgccg gtccgccggt cccagaggac ggggaccgag
     4141 atgtggccgc cgtacccctt ctcggtcgcc tcgtagccct gctccagcag ggtgaagccg
     4201 ttgacggggt cgtggccccg gcgtttcctg aacgcccagc ctcggccgtc gcgctcgtcg
     4261 tccacgtagg acagcgtgac cacgtcttcc agtcctttga gcttgcggac gatggcggcg
     4321 cggtgagcgt acgggcagac ccaggcgacg tagaggtggt agcggccggg ttcggcgcgg
     4381 aagccgctgg agccgtcggc cgtgacccgg ccctggaacg ggtagaccgg gcggttccag
     4441 tccggcgaca ggtgcaggcg gcccgggccg tagtggccgt acgtgacatg gtcgacaggg
     4501 gtcgcgtaga ccgccgtctg cgtggagatg gacacgggtc ctccggggtt caggagtcgg
     4561 ggtgggccag gaagcggccg aagcggccct ggtggtagag cagcggtcgg ccgggccgct
     4621 gcacgtccgc ctcggcgacc aggccgacca ccaggatgtg gtcgccgacc acggcccgct
     4681 cgtagggcag gcagacaagg tgcgccgaga cgtcctgcag caacggagcg cccagcggtc
     4741 cggggcgcca gcgggtgggc gcggcgaacc ggtcgatgct cttgcgggcg aagcgggccg
     4801 ccaggtcggc ctggtcgctg gtcaggatgt tgaccgcgaa gtggtcggcg ccgctcagct
     4861 ggggccaggt ggtcgaggaa cggtccacgt agaaggagac caagggcggc tcgaggctga
     4921 ccgaggagaa ggacgtggcg gtgaggccca cgggaatgcc gtcgctctgc gcggtgataa
     4981 tcacgacccc gctggcgtgc acggcgagcg cccgcttgaa ctggtcggcc gcgacggccc
     5041 gatcgggcag tgtgtcagtc atgcgggtgc cccgttccgg tgcgggcggt cagcggggtg
     5101 gccggatgtg ggtgatggca tgatcacgag aaagttcctc acggagaagg catgctcacg
     5161 cggcgctccg gcggctgccg gggcgcggcg gaaaggagaa gtcggcggtg agggcgtggg
     5221 cggcgccggc cacgccggga gcgcgcgggt gggattcggc ggctacgggt ccgtgatcaa
     5281 cgacactgtg cgctggctac gtggcagaaa tccacgtgag agcgcctggt cagaagaatg
     5341 ccctggctca taccaacgaa gctaagccgc gatctccgaa aagtcaatat ttcctactgg
     5401 tttagggggt aataacagcc tcgggctgga accgcggcca gctcgtccgc aacagcaagg
     5461 tctagccgtg ggctccctgg cgatggcttt gggtaggtga caggagccgc aggtcgcggc
     5521 cgcgttgcac cgccgacgag cggtcggtgg cgccgagctt ggcgtagata cggcggatgt
     5581 gggtgttgat ggtgtggagg gaaaccggga gctcgctggc gatctcgagc cgggtgaggt
     5641 tcgtcggcag gtaacgcagc acccgtagct cgctggggct gagcttcagg ccgggtggat
     5701 gctccgcttt cgcgggagcg ccgtcgtgga cggcgccgag gatgtcggcg accagtgcgg
     5761 tgtgcgaggt tccccgcagg gctttcagca gctgccacgc gccggtcatc gcgaacggga
     5821 agatcagccg gtccggctcg gcgagagcca gtgcctgctc catgctggcc cgcgccggct
     5881 gccgcgcctg ctcggcgaac gcggcatcga ccgcgccgac gtcatcgtca gcggccttcc
     5941 ctgggcgctc ctttctgcct cccttcagca tcagctcctg gaagcggtgg ccgccggact
     6001 cggacggcag ggagccttca ccgccttcac ctacctccac gccgtacccc tcccctccgc
     6061 caagcgcttc cgccgcctgc tgtccgaact gttcgaggag gtcgtgccca gccggaccat
     6121 ctggcgcaac gcacccccgg ccttcgtcct ccacgcccgc cgacctcgtc agtgtgatgc
     6181 gcaggcgtcc gggagctagg cattccagcg gtgcgtggcg ggagagtctc ttgtgtactg
     6241 ggcccagggg gtgtcggtgg tgggggtgcc ggtacggata aagccgagcc aggcggagca
     6301 cagccgtcgt ggagtcacgc tcgcatgcgg cctgcgcctt tctacagctt tgcctcttgc
     6361 cgggagactc cgcggaccac cctcgctaga gtgagaaatg cttcatgcgc cgtactggcg
     6421 cttcccgggg gagcccaagt cgacgctccg tcagcccggc atcatctggg cgctcatcac
     6481 gtcacggagt gatctctgat gctcgaacgc cttctagttg ccgccgccgt ggtggcatcc
     6541 gcaatcatcg gtccgatggc gctcaccacg ccatccgcaa gcgcggccca cacgccgagc
     6601 acggccatcg ccgcccaggc tgccgccaca atggcgcagg atcccgtccc tggggacgag
     6661 gacgacgagg accgcgcacg ttgacctaga tgaccgctgc gatggacgcc ctgtcggcgg
     6721 gcagcgggat cgcgttgaaa cggaatcgcg gccaccccgt ggtgcaggtc atcgcggggt
     6781 gagtccgtga cgcccggtct ccacagcaat ctccggggtc actgcggcgg cggagatgct
     6841 tgcctgcggc tgaggtcaac ggtttcggtg gtgaccccgg gctcgccggc gtaggcggcg
     6901 gcgagcgcgt tgtggtcacg ccctgcggcg atgactcgcg ctccggcgtc ccgggcggcg
     6961 acagcgttcc tcaccgcgag caccgacccg gacgtccaac agatcatgct catcgacgcc
     7021 cctgccgtgc tcggctggag cgaatggcgc gcgatggacg agggcgcgtc ggcacaccat
     7081 ctagccgaag cgctcaccac tctcatcgaa caaggaacca tcgcccctca accggtcgaa
     7141 ccactcaccc acctgctgtc cggcgccatg aacgaggctg ccctgtggct ggccacatca
     7201 accaacccca acgacctggc cgacacctgg gccgcactct cacggatgct cgaggcactg
     7261 cgccacaagt agacccggcc cgcaacagcc cagctcccac ggcccctcga aacgagcggg
     7321 agtgtcgaaa acctggcggc tgcccgcacg ttaccggcca actgcatcgg cgtgatctgg
     7381 aggcaggagc aggcgtcaca gggcaggtga cgggccgtcg gccccgaggt ccgtcgcgat
     7441 ggcggcgaac tcgccgatca gggggttccg gcgggcgctg tcccaggcca ggcacacctg
     7501 gttcggcgga atgtcggtga ccgggacgta ggtgacgtcc ggccgggtgt agaaggccac
     7561 caccgacagc ggcaggacaa cgacgccgtg gcccgcggcg acgtgttcca gtttctcctc
     7621 cacagcgtga aagaccggcg cagggcgacg ccttcccggc cgccgcagct cggtggcgat
     7681 gtcgcgccat tcgggaacgg catcggggtc ttggaggagg tgttcgtcgg tgaggtcggc
     7741 gatgccgatc atgtccttgc ccgccagatg gtggccggca ggcagcacgg cgacacgcgg
     7801 ctcgctcatc agcggccgga ctcgcagccc ccgctggtcg atcggcaagc gcacgtagcc
     7861 gatgtccacc cgcccgtcgt ggatggtctc ggtctgatcc tcccaggtcg tgcgcaccac
     7921 ctccacggtc agcccggggt gacgttcgcg cagtgcccgg accgccggag tgacgatcag
     7981 cccaggcatg aatccgacgg tgaagatgtc ggcgccgcgt gcggcgcgac tgacgcggcg
     8041 gcgcagcgcc tcggccgagg ccagcagcgg gccggcgtcg gcgagcagtt gctcgcccgc
     8101 agaggtgagt tcggtggccc gcctggtgcg tacgaagagc tgaaccttga actcgtcctc
     8161 aagtgcccgg atctggcggg acagcacggg ttgcgcgatg tgcagtgcct cggccgcccg
     8221 cccgaaatgc agccgctcgg ccaccgcaac aaaatatcgc agcttccgca gatcgacgtc
     8281 caccagcgcc tcctcccgcc tttgatgccc acagggtatt acagtcgtgg cagagggtct
     8341 tggacggcgg cgatggaccg ggtccatcgt agaggtgtcg aatcgcccta tctgaaggac
     8401 cgaatcatgg atctgcaggg tcaacgcgtc gtcgtgctcg gcggcacctc gggtatcggg
     8461 ctggccaccg cggaggcggc cgcgcgacag ggtgccgtgg tcacggtcgc ctctagccgg
     8521 cgggccagtg tcgaccacgc actcacccgg ctgcccgacc gctgcgacgg ccgcgtcgtc
     8581 aacctcaccg acgcccgggc ggtgggccgg ctcttcgacg accttggcga gttcgcccac
     8641 ctggtctaca ccgccggtga gccgctgacg ctgatgccgc tggacacgct cgacctggac
     8701 gcggcggggc accttttcgc gctgcgctac ttcggcgcgc tgggtgcggt ccgcgccgcg
     8761 ctgccgtacc tgcgcaagga tggttcgatc accctcacca ccggcatcgc caaggaccgg
     8821 ccgggcccgg gctgggcggt cgcggcaagc atctgcggcg ccatggaggc gctgaccaag
     8881 gcgctggccg tcgaactcgc gcccatcagg gtgaacgtcg tgtcgcccgg cttcatacgg
     8941 tccccgctgt ggtccgggat gggggacgag gagcgcgagc ggatgtacac cgaactcgcc
     9001 gccgcgatcc cggtggggcg ggtcggcgag gtcgaggaca tcgcccgagc ctacgtgttc
     9061 ctgatgacag agccgttcgc taccggaacc gtcctcaccg tcgacggtgg gcacgtcctc
     9121 gtctgatcca gaccgcgccc acccctatgg gcgacagacc gtccggcacc ggatgacaac
     9181 caggctggcg ccgtacgccg cgcgggcggc cgggaccgac tcatgcgatg gctatgagac
     9241 tgcttgacct ggtgacgcgc gaactgtcga gcccgcccga gtcgtgccga ccggggacag
     9301 caccagatcg tcacgacgtg ccgagcaacg atcttgtcac gcatcggcta catatagcga
     9361 tcaaagagat gcatagagtg actgtcggga gtcgttctca agtccctcat acctgcggga
     9421 catcctgcat cagcgacgaa gggcagcgca tggccacgga tctccaggtc ctcaagatag
     9481 accggtcgtt cacctacatc gacgtcgacg gcaatggcgt catcacccgt gacgacctgc
     9541 agggcctcgg cgcccggctg ctcgccggct tcggagcctc gccggccggg acacaaggcc
     9601 ggcgcgtggc cgactccttc gacagcctct gggacacgat cgccgacgcg gccgacctca
     9661 accacgacag ccgcatcact ccggacgagt accgttcctc gctgatcgcc tcgttcatcg
     9721 acggcgaccg cttcgagccg atcttccgcc cggcgatcga cgcggtgctc gccgtggccg
     9781 acaccgacgg cgacggcctc atccagccgg aggagttcca gttgatccac gaggcgttcg
     9841 gccggtccga gcaggacagc gagcaggcct tcgccgcgct cgacctcgac ggcgacggcg
     9901 cgctgagccg tggcgaactc ctccacgcgg cgcgtgacta ctacacctcc gccgacccca
     9961 gcgcgatcgg caacctgctc ttcggcagcc ttccgacccc atgacggcac tggccgatgc
    10021 ccggccgcac ctgcgccccc tcctccagcg agtccccgcc ctgcgcggcc ggtgccgcat
    10081 gcacccgcgc gtcgatgccg ccgggcagca ggtgctgtgc tgggctcggc aggccggact
    10141 ggccgacgac cctaaggctt cgcggcggct gcacgccatc gacggccacc gcatggccgg
    10201 acgggtcttc accgactcca gcgacgacaa actcgtgcag ttctctcaat ggctcacctg
    10261 ggtcgtgctg ctcgatgacc actgggacga gcgctcctgc cccaccccgc aagagatcga
    10321 ccacacctac acccggctgc tccacgtggt cgaccacgat cgcgaaccag cgcacgccga
    10381 ccccatggaa cgcgccttca cccagctctg gcaggtcacg tcggcagaca tgagccctgc
    10441 ctggcgcggc cggttccgtg cccacctgga gctcaaccgc cagagcaccc actgggagat
    10501 ccgcaccaga cgcaccgggc agttcagccc actggccgac tacccacgcc accgccgcgt
    10561 cgcctccgcc tcgttcatct tcgacgcggg cgaggccgtc ctcggcaccg aactgcccgc
    10621 gtccctggcg tgcctgccgg cctggagcga ccttgccgac gccgccaacg acgtggccgt
    10681 ctggtgcaac gacgtcctca ctttggacaa ggacgagcac gaggccgatc tgtccaacta
    10741 cgtcctggcc gcccagcacc atctcggcct gtcccctgcc gcggccatct cctgggtgat
    10801 cgaccgcatc gccgcccgca ccaccgacct gcgccgagcc gcacgcgcgc tacccgccgt
    10861 ctaccggcgc ctcgacctgt cccacggcag cgcccgggca gccagcaagg tcgcctgcgc
    10921 ctacctcgcg cttccccacg ccaccctgga gtggacctgc gaagcggccc gttaccggcc
    10981 gttgtccagc agtacgtcgc aggccggggc atggccggcc cgcgagtgag ccagcgtgcc
    11041 cgcagagcca gttctccaca accgccggcc cacatcctca cctactggaa ccgtttcggc
    11101 ttatccgcga ccacgcaggc cgtcctcagc cgcgcggcac gcgaggccct ccttgcccgt
    11161 caccgtctga ggcatgtggg gtgtcgagat gcggccagac caccgcgacc ctctgcgcgt
    11221 ggagctcgca cctcccccac cggagcctgg tcgggcatag cgggctgcca cctgcgggac
    11281 ctgctcacgg agggggccgg ggctgagtga tcaggtgctg gccttgttgt cggattctgg
    11341 agtgactccc agccgggagc ggagaaagtt cacgatgatc gccatgactt gcgtgctggt
    11401 ccagattcgg ggagcgctcg acagcgcgcc gtggccggcg ccctgaagta cataccgggt
    11461 gctgtccacg tcggcacggc gcagggcttg gtgcaggcgg gcggtttgcg caggtgtcac
    11521 gatgcggtcg tcgctgccgt gtagcaagag aaacggcgga gtctcggatg tgatgtggct
    11581 ggccgggtcg gcgttgatca cttcggcggg gtggtcggca aaggcccggc cgggtccgag
    11641 caggtaggtg ggcagtgctg cgcccgtcgt ggtgtaggcg gtcaccgtgg ccgggtcgaa
    11701 gccatcggcg atggtagcca ggtgggaagc gccgaacacg tcgatcaccg cgtcgactcc
    11761 cgagccggtt accgccgcga cgccactgcc ggggtcggtt gcggccatgg cagccaggta
    11821 gccgcccgcg gattcgcccc acagcgcggt ccgggcgggg ttgatcccgt aatggtcggc
    11881 gtggaggcgc agaaagctca gcgccgcggc gacgtcggcc agtccatcca ggtaggtggc
    11941 gccgtcacgg acagtgcgat agtcgatgct ggccaccgcg aaccctgcct gggcgacgca
    12001 gtggcgctgg cgggcggcca tcgcgcgccg ggcggtgacg aaaccgcctc cgggcagata
    12061 cagcaccagc gggtacgggc cgggcgcctg cggggtcagg atgtccatgc gcagcttgcg
    12121 tgccggagcg gcgtacacga tccctcgata cgcgcgggcg ctgcggccgg gcttgatctg
    12181 gtcggcggac tctacgtgca gccggatgct gtcggggtcg tcatcggggg cggccacgct
    12241 ggacaggcgg atcgggcggc cgctcagtgc ggccagtgcc atgatcaggc gcatggtgtt
    12301 catgcgaagc tcctttcggg caggggacgc catgggcgcg ctgccagtag tgccaagacg
    12361 gccagcgcca tggcggccag catgaccaac gccatcgcgc gcagcgtggc gccgctcagc
    12421 ggggcggcca gggcgccgaa caggtaggcg gcggcgccgg acagcgcgga tgcggcaccg
    12481 gcgcgggcgt ggccgatggt ctgggtgatg gtggtgacgg cggggaagat accgccgatg
    12541 ccgaacagca tgacggccag gcacagccag gtgccggcca aggtgggcgc cagcgtggcc
    12601 tggatgacca gcgcgagcgc gccgagtgtg ccgatggcga ggtagcccga cagcagcgcg
    12661 ggcagcgcca cccgccgggc ggtgaggccg aaacctgcgc tggcgacgag catggcggcg
    12721 gcgttgacgg agaacaccag cccgtactgc acggcgctca gcccgaagcc gttctggaag
    12781 acgtagctgg agcccccgat gtagacgaac atcgcgccgg cggccaggcc gagcgtcagg
    12841 gtgtacccgg tgaaggcgcg ctggcgcagc agcgccgcca tggaggcgaa tgccggccgg
    12901 aggccgccgg gtgatcgccg ggcgggcggc agggactccg gcacgcccag caaggttgcc
    12961 gccagcatca ccagaccgag ggcggtcagc gcccagaaca ccgcacgcca gccgtaggcg
    13021 gtcacgatca tgccgcccag cagcggaccg aggaccggcg ccactcccag gatcatcgcc
    13081 aggatcgaga agtagaccgg cagccgcggc ccggcgaagc ggtcggtcag caccgcgcgg
    13141 gccagcacca gcccggccgc ccccgcgcag ccctgcagga aacggccggc caccagcagc
    13201 ggcgctgtcg gcatcagcgc gcaacaggcc gacagcagcg cgaaggcagc ggtgcccgtc
    13261 accagcagcc ggcgtcggcc cagtccgtcg ctgagtggcc cgatcaccaa ctggccggcg
    13321 accagcccga tcaggaaggc gctcatcgac atctgcaccg tcggctcgcc cgcggccagc
    13381 tctcggccga gctcgggaaa gccgggcacg tacatgtcga tggccagggg cgccactgcg
    13441 gtgagcaggc ccaagatgcc cagcaacagg atggggcgcc ggagcgctgt ggtctctatc
    13501 atggcaacaa aggtaaccta gtagtcaacc agttaacaat gttgtggtga ggatggcatg
    13561 agccggagta ccgatcgcgt ccgtgagctg tgggccgcgg cccgtcccga cctcgacact
    13621 tccccgatgg aggtgatcgg cccgctcaaa cgtgtcatcg ccctgctggg cgaggcgctg
    13681 gacccgctgt acgtcgacgc cgcgctcacc ggcacggagc tcgacgtgtg tctacggttg
    13741 cggcatgacc ccagcccgac catcgcgcgc cggctggccg atcagatgcg ccactcgcgt
    13801 gcggcgatca gcaagacgct gacccggctg gagagtcgtg gtctggtcgt gcgagaaccc
    13861 agcccggccg atcggcgtgc ctcgttggta cggctgacgc ccgcgggcga agcggccgtc
    13921 gatgcgatct tcccccggca actggctcgg gaggccgagt tgctggaggg gctgggcgcg
    13981 gatcgcgaac gcgtgatcga ggcgctgaac ctgttggccg atgtcctggg caagcgcatg
    14041 tgagctggtg agcgcgttgc ggatgtcgtg aggtggtgcc gatctcagcc atcggcagcg
    14101 tggtctaggc caggacgacg agccggccgg gcgcgacaca cacgtcgccg ggcgaggagg
    14161 gccaggcgtc ggccatgccg gcactctggc ccccatgatc accgggtcac cgtccagcca
    14221 gaacggacag cggcttcgtc gcgctcagga ggcgccgact acgacttcca cccggtcggt
    14281 gtagaaggcg acgtggtcgg cgatgtctac gacggcgtcg tatggctcgc ggtaggacca
    14341 caccgcgtcg gccaggccgc cttcggcgag ggcgatgctg tagtaggacg cgtcgccctt
    14401 gtacgggcag tacgtccggg tgtcggtggc tgcgagcagc gtctggtcga cgtcgccgag
    14461 cgggatgtac tggaccggcg ggtagttcgc ttcccgcagt gtcagggccc tggttgtgtc
    14521 ggcgacgacg cgctcgccga cgcgcgctac gacgcgctga cccgtcttct cgatggtgat
    14581 cggatggtcg gctccgggga tcttgggttc ccgtgtcgtc atggtcttct cctcgttctg
    14641 gtggcgggtg gctcaatcgg cgaacgtggt ccaccgggcg ccaccgctct cggcctcttt
    14701 gagtttcgtc ggtcccggcg gtgactttac ggtccagggc ggcggcccag aactgtgcgg
    14761 cgtcggcgcc gtcaaacgac gctccgaatc aaggtggtac tgcttcccac catgagcgca
    14821 tgagtagact agtctgtcta gttgatgctt caatcgcaca agccgccctt tctaggcata
    14881 agacagcagt gtagatgcca tgttgatcac tcagatttga caagacgaga tcagatcact
    14941 ctactggaca gtaagccaag acagacaggt ctaactaatc gaagaaggcg caactatgac
    15001 cgagatgcgc acagcactgg tgacaggcgc gacgtccggg atcggccggg ccgcagcgtt
    15061 gaagctcgcc caggacggat tcagagtcct ggttcacggc cgcgacgccg agcgcggggc
    15121 cgcggtggtc aaggagatcg agagcgccgg cggcagcgcc gagttcctcg ccgccgacct
    15181 caccgacgtc cgcgccatca ggcagctagc ggctgtggcc ggggacgtcg acgtcctcgt
    15241 caacaacgcc gggttcgcct ggttcggtcc caccgccgac ctggaccccg acaggtacga
    15301 cgagttgttc gacgccaacg tacgcagtgc gtactacctc acggccgcta tcgcgccgaa
    15361 gatggccgag cgcggccggg gcaccgtcat caacctgggc agcatggccg ggcagatcgg
    15421 cctcgcaggc ggcgccgcct acagcgccac caaggccgcg ctcacctcgc tgacccgctc
    15481 ctgggccgcc gaatacagcc cgcagggtgt gcgagtcaac accatcgccc ccggaccggc
    15541 ttacaccggc ggctcgtcga gggaaagtct cacagccctc gggaaaacca cgcttctgtc
    15601 tcgcaccgcg gaggcagagg agatcgggga cgtcatcgcc ttcctggcct cgccggctgc
    15661 cggctacatc accggcgccg tcatccctgt cgacggcgga cgtaccgccg tctgatccgt
    15721 accgcatcta tgaggagccg agaaatgggc aagcctgcca ttttgatcac cggcatcggc
    15781 cgggccggtc gacggcggcc tgacaaccaa ctgatcatct acccggacga caaccacggg
    15841 gcccaccagt agcgcggcga ccacctcggt gcgctaactg ggaagacagg tctgtctagt
    15901 cgtattatcc ccggtagaag tcgaatatgc ctccgaatgg agcagtagac tgtacctcca
    15961 gtctgaagaa ggaagccccc atgcccagca aggtcaacgc ctcaaagccg tccgcgcgtg
    16021 aacgtcttct ggccgccgcc gacgacctgt tctaccgcga aggcgtgcag accgtcggca
    16081 tcgaccgcat cgtgcagaag gccggcgttg ccaaggcgtc gctctacaac ctgttcggga
    16141 gcaaagacga gctggtgcag gcctacttgg acgcccgcca cgccgatacg cgtgagcagg
    16201 ttgagcgcac cctgacccgg tttcggaccc ctcgtgagcg tctgctgggg gttttcgacg
    16261 cacagggtca gctgttcacc gagcccgatt tcaacggctg tgcgcatatg acggccagcg
    16321 cggaggcgcg gcccggtagt ccgatcgagt gcgcggcgga gcgataccgg ctgtgggtga
    16381 ggacgctgtt cacggatctg gcacgggagg ccggcgtcgc cgactttgaa ggcctcgcga
    16441 ggcagctgca ccttctgtac gacggcgcgg gggtttcggc gcggatggac caggatccgt
    16501 cggcggcgac cactgctcgt gcggcggctg ccgcgctgtt cgatgcggca gtcagagacg
    16561 gggatgcctc cgctcggatc ccacgaggat gatgaggacg agccggaacg tgacagcgcg
    16621 gcgacgcagc atcggccggc attcccgtca ccgcgacggc tcaccaagag catgaggcgt
    16681 caaaggatca ggaggccacc gaaacggcgt ggcgcaccga cgcgggatca gcggccagcg
    16741 cgagcaggca gtgggccacg tcggcgcggg tcgtgctgag gccgcccctg aggttggtgt
    16801 cccacgccgt gcggtaacgg cccgtcggtg cgccgtcggt caggcggctc ggccgcacga
    16861 tggtccagtc gaggttcgtg gcacgcagcc gacgttcggc ttcgcgcagg tcggcgtagg
    16921 agtgcttgaa gagtcgctgc acgatgagcg gcttgaccac gtaccggacg agcactccgt
    16981 cgcccgcgtc ggccacgagg ccgctggcgc tggtcatgag caggcgccgc gtgcggccac
    17041 gctccatggc cgtggcgatg gcgctgatgc tgtcggcgca caccgtggtg ggcgcccgat
    17101 cgcgggagcc catcgcggac agtacggcgt cgcggtcctt cacggcgggc gcgatggcgt
    17161 cggggtccat caggtcggcc tggaagatgt cgaggccgga cggcaggtct gcgggcagcc
    17221 gccgggggtc gcggaccacg gcggtcacct cgtgcccggc ggcgagcgcc tgacgaagca
    17281 gttcggtgcc ggtgcctccg gtcgctccga agatcgtcag cttcatggtg cctcctttgc
    17341 ccatgcctat agtgagtgag gactcactaa ccagtcaagt cagaggaaat tgtcatgcct
    17401 tgagaacggg caggggtgcg ggaaaccgcg acgcggcaag gcgtcgagag ggggcacagc
    17461 ctcctacgcg cggacgtcga agcccagtgc ggtggccacc acggtcgcct ggaaggagtc
    17521 gatgatcgcc ttcttcagcg tgaccgtcga cgggtccagg tcggacaggt cgctgccccg
    17581 cagatcgcag cccgtgaggt cggcgccgtt gagccacgcc cccgaaaggt cgcaacgtaa
    17641 cacctcggcc ttctccagcc gggcgcccgt caggtcggcc tcgcgtaggc gtaccccgtg
    17701 aaaagcgctg ccccgcaggt cggcgccggg caggccggtg aacgaccagt cgccgccctc
    17761 gaccttcagc agcccgtagg agcagccgtc gaacatgctg cccgtcatct tgcacgcctt
    17821 gaacgtcgcg tcgaagaacg agcagcgcga gaacgtgcag ttgaggaaca tcgcgtcctc
    17881 gtgcacggac acgttgaaac gcacgtcgct gaacgtgcac tcctcgaaga cggagccgct
    17941 gttggtcagc tccgtcatgt ccacgtcgac gaacaggacc tgatggtagg tctcctgcgt
    18001 caggtcgcgg ccgtcccagt cggccgatcg gaccgccgtg ccggtcgggg gacggctttg
    18061 tttgcggtcg gccatcatcc ggcgacctcc gttcgctcga tgacgaccac gggcagctcc
    18121 ctctgtgtct tgcgctgcat gccggagtag gtggggaaga tccgcagcat cgactccgac
    18181 agccgttccc gctccgcgcc gtcggcggtg tgggcgcggc gcgagaagtg gtcggcgctg
    18241 acctgcaggt gcacggccgg gtcggtggcg aggttgaggt tcctggccag gctgtccgtg
    18301 atctcacgcg cttccatgga gccctcctcc cgcgtccccg cgagcctccc acgcgccacc
    18361 gacagaatcc gttccggccg cgtacgggtg tggccggtca cggcaggccg gaacgtgcgg
    18421 gccggaacct ggaggccgga acctggggcg tcgtgccgat ggccggcgcc catccgaccc
    18481 gcgccgactc gcccccgcca ccacgccgac ggaccgctga aaacccgccg gggcagcccg
    18541 tcccagtgcg cgtgacgggg gccaggcccg gaccggggag gaacgggggt gacgatggtg
    18601 gctggtcgac tcggacgggc ggacgggcag ccgggcagcc gggcagccta gttggcaggg
    18661 cgggcgggca agcctagttg gcagggcggg cggggcggtc gtccttcagc tagtcggctc
    18721 tcaggagatc agccaggcag tcagccctca ggagatcagc cctcaggtgg tcagtgcttc
    18781 tccaaggact ggtcccggca gccggtcggt gcgttcaccg ggttacagcg ggcgaccccg
    18841 ccgccgggca gttcggccgt gtagtcgctg ccgtgcctcg ccgacaggcc gaccacgggg
    18901 aagtccgtgc tgaccatctg cgcgccgctg tcgagggcgg ctcgcagccg gctcgtgtcg
    18961 cccgagcggg cctcgacgaa cggtacgtcg gagcgggtgc gcacgtaata gccgcgccgg
    19021 acgaggtcct ggatctgggc ggtgttgtcg ccctgcggct cgttccagcc gacgaacgcg
    19081 gcgtcggcat ggccggggcg ggagttggtg aacagcaccc tgccctccaa gctgggccgg
    19141 ccggtcaggt acggggtctg gatctccgtc gcctggttgt ccatgaagaa catcaccttg
    19201 ccgcgcgacg acgacagctc gggccagccg tactggagca ccgactgttc cagggtcttg
    19261 ccggggcggc gtacgttgtc cggggtgatg aggcggtcgg ccgggaacac ggagtggatc
    19321 tcggcgtcga gcgcgtccag cagggtggtg tcccacttcg ggctcttggc gccgccgagg
    19381 gcctccttgg ccgggtccgt gctcttcagt tcggtcagga tcgtcagcgg cacgtgtccg
    19441 gggtgcgcgt cggaccactc ccgtacctgg cgcaggcagg tgaccagggt ggagcagttg
    19501 gtgccgtagt cgtggtcggc ccagtggagc accttgaagc cgggttcccg cagcgcgggg
    19561 tcggtcagcg gcggcaggcc cgcgtcgcgg cggacgagcg gggcggtgta gaggccgcct
    19621 ttcgggtcgg ggaacacgtc gagttcgatg ccgcgcacgt gctggtcctg gaactggcgc
    19681 gggagcgcgg ggtgggagaa ttgcaggttc caccagttgg cgtcggtttt gcgctgaacg
    19741 tccttctcgg cgtcggtcaa ttcccggtgg tagctgttgt gcgtggccat ggtctggatg
    19801 tggttgatcc gcagcggccc gcgacccgca gcagcagcgg ttgcggcggc aggcacagca
    19861 tgaaccacag tagcggcggt ggtggcggcc agcagaccgg cggcgatcag ggcgggggcg
    19921 cggcgcatgg agctcctagc gttcgtgatg tgatgggaga gaccgtctga ggccccggtt
    19981 aactcacgat cacgaaatat ccaaacaagc caagaaaaat gcgcaaacgt ccagattcac
    20041 cgctgatacc gcgcagattt acacttcgaa gtcacggggg tgcgaccaca gattcgcata
    20101 gcgtacagat cgccaactga ggccagagat ctcgttcagc tggagcttct ttgttgatct
    20161 tgtcgaaagt cggtcgttgg tgtcgctctc tacgcatggc cgccctgcgc tgcccctgcc
    20221 cggctggcgc tggtgtccat cccgcaattc ggtgagggcc tgttcgatgg ccttccgtcg
    20281 cgcacctgcg ccggcggccc catggcaatt gacggcaacc gcccgcggac cttgaaaatt
    20341 acatcgccgg agcggccgga cgcgcagctc gcggggccgg cgccgcgaca ggtgacggat
    20401 cagatcattg ttgaggcgtc gaaaacggca tattctacga gtttcccgtc attgacgatg
    20461 atctcgacag atcggtcaag gagcccgcca tgcgcgtgcg aacgaccccg tccctgatca
    20521 tgattctctt agagcctgct gacaaaggct taagtgctgg tgggcagggg gccgtagagg
    20581 gctggtccga tcttgttgag gtagccctgg tgagaccatt gggacagctg gacgcggaag
    20641 ctgttgatgt tctcgat
//
