LOCUS       NZ_JAHFZY010000005     26066 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Actinomadura sp. NEAU-AAG7 Scaffold5, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZY010000005
VERSION     NZ_JAHFZY010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura sp. NEAU-AAG7
  ORGANISM  Actinomadura sp. NEAU-AAG7
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 803282)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Actinomadura oryzae sp. nov., a novel actinobacterium with the
            activity of releasig potassium isolated from rhizosphere soil of
            rice in Sanya
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 803282)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, 600 Changjiang Road, Xiangfang District,
            Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603865.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:10:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,952
            CDSs (total)                      :: 7,871
            Genes (coding)                    :: 7,813
            CDSs (with protein)               :: 7,813
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 6 of 58
            Pseudo Genes (incomplete)         :: 53 of 58
            Pseudo Genes (internal stop)      :: 1 of 58
            Pseudo Genes (multiple problems)  :: 2 of 58
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:01:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 412901
            Orig. end                         :: 438967
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZY010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26066
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26066
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26066
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16066](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16066)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(382..543)
                     /locus_tag="KLI87_RS24630"
                     /old_locus_tag="KLI87_24630"
     CDS             complement(382..543)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLI87_RS24630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLI87_24630"
                     /product="hypothetical protein"
                     /protein_id="WP_214618867.1"
                     /transl_table=11
                     /translation="MNQRNSTLSRHLTSEGTVIWSRCACGRLRMDLVPHGSAPRLTAGP
                     CAHGHPPK"
     misc_feature    569..584
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     misc_feature    complement(601..617)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    601..617
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.18"
                     /tool="antismash"
     gene            616..1569
                     /locus_tag="KLI87_RS24635"
                     /old_locus_tag="KLI87_24635"
     CDS             616..1569
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077754.1"
                     /locus_tag="KLI87_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24635"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_214618868.1"
                     /transl_table=11
                     /translation="MIDLRRLHLLRLVHQYGTVTAAAEAMHLTPSAVSHHLRELARELG
                     VVLLEPQGRRVRLTPAAHLLIGHADALHARWEEALSDLESHRAGAAGPLRMCGFTTAVS
                     GLIAPAAGRLTAADPDLAIEIRECDTDVAMGLLAAGETDLAVIEPTPEAPPPGDPRFDR
                     EPLLEEALDLIVPVGHPLARRGTAVLEDAASEAWISVEPDGCAHHQQVMTYCAAAGFTP
                     RIAHNATTWSVIWALVANGLGVSLVPRLADGQSGQTVVRVPLTGDSVPKRRVLTCVRRG
                     SRTHPLIARGLAALHEAVPAQCDLLPAATRAVPVAS"
     gene            complement(1573..4116)
                     /locus_tag="KLI87_RS24640"
                     /old_locus_tag="KLI87_24640"
     CDS             complement(1573..4116)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024116.5"
                     /locus_tag="KLI87_RS24640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24640"
                     /product="ABC transporter permease"
                     /protein_id="WP_214618869.1"
                     /transl_table=11
                     /translation="MMVKLVFRGLAAHRARLLLSVVAVVAGVAFVSGTLIFSATLSRSF
                     DRAFDDLGRGTDTVVRARQSFRTGPGERAAPRPVPASALAAVRRAPGVAKAEGVITGFA
                     AAVDRQGRIAGAEPQTGVAWSGDRDLSLTRLTAGAPPRAPDEVAMDATTARDARYRVGD
                     RVTVALRSGTRTFRLTGLFRVGDSALGSSISMTAFAPDAAPRLLGQRPGTYERIVVHAD
                     GGVTQERLRDAVAAVLPPGVEAVTGAEAAAEQAGPLKDIIKIMRTFLLVFALIAVFVGS
                     FIIFNTFAMLVGGRVRELALLRAVGASRGQVTRSILGEAAVVGLAGSTLGLAAGAVVAL
                     GLARLMTLVTGGEELPFGPLALPASAVLAAYLVGTPVALAAAFVPARRAARIPPVAALR
                     EDAAPPRPLRRRVLGGCAVLAVGGILAAAGLAGDGTSGLTLAGTGAALLFAGVVVVSPA
                     LSRPVARVLARPFARFGGGAGRMGARNAVRDPRQTSATASALTIGLALIATVSIIVQSL
                     AASVDRQLEAALTADYQVTGRSQVTPVEAGAAAAVGRVPGVRAAIPVRTARFRLEGAVQ
                     AATAGSPGELLAHFRLPLQEGSAAVRGEDLLVGRSVARDRGWRIGGTLPGEYQDGTRRT
                     FRIAGIYADRPALTPSAPTVIIDWAGYRAHDPDAPIERIEVTVAGARRAALESALAPWP
                     NLELKDRAQVKDDAAGEIDLFLTLVLGLLVLSVLVAALGIVNTLALAVTERTREIGLLR
                     AVGTQRRQLRRMIRYEAVVVSLFGAVLGVGTGSVLGVVLQKAIAGGEDGMEVLAVPYGR
                     LALCVAAAAAIGVVAAVWPAARAARLDILQAIATD"
     misc_feature    complement(4095..4109)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            4258..5544
                     /locus_tag="KLI87_RS41615"
                     /old_locus_tag="KLI87_24645"
     CDS             4258..5544
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="KLI87_RS41615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24645"
                     /product="sensor histidine kinase"
                     /protein_id="WP_214618870.1"
                     /transl_table=11
                     /translation="MRLTPPPAPPGRDLAADAVAVVCALALSLQTAAGPDSVLRGHHGA
                     TAAVVALPALALAVRRRFPMTVAWLTAAVAALLDAVERLAPGTLLRDGPPGAFDPIVWW
                     PPALPFAVYAAMAFPRDGDRPVWARALPVVALVPLVGLTQDVIPDESIRRVSGQETSSV
                     ETMVFRSMAMLVAAALLGMYAAARRRVLQGLTERAERAERERHLLAERARAEERARLAA
                     EMHDVVAHRVTLMVLRAGALRVRAPDEETRVAAEELRDDGCHALEELRDVIGLLRRGAG
                     AAGAAPAPASGPLPDLSALVAESAAVGVRVELVERGEPAPASPAVGRTAYRVVQEALTN
                     ARKHAPGAAVRVEVGYRSDGVRLSVLCAAPERDPDAALAASGSGTGLAGLRERVETVGG
                     TFSAGPAGDGFRVEASLPAYVPLPTPPAP"
     gene            complement(5511..6014)
                     /locus_tag="KLI87_RS24650"
                     /old_locus_tag="KLI87_24650"
     CDS             complement(5511..6014)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019656.5"
                     /locus_tag="KLI87_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24650"
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_214618871.1"
                     /transl_table=11
                     /translation="MTTPEGIRSGDVRVGDAERDAVMVALHDHFAAGRLDREELDERLG
                     TTLAARTRGDLRAVVLDLPDPQGLAVPEAAPARHHHRGRPHHLGHHHLGHHHGRHRHGP
                     PFPLLLGLFLVLAFTMGPGPGFLVVLQVALAVWAVRALLMAFGHRHLRHHAHRQGAGGV
                     GRGT"
     gene            complement(6011..6811)
                     /locus_tag="KLI87_RS24655"
                     /old_locus_tag="KLI87_24655"
     CDS             complement(6011..6811)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893187.1"
                     /locus_tag="KLI87_RS24655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24655"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_214618872.1"
                     /transl_table=11
                     /translation="MGATHRSGPDWRWAFAAAAIGAKAAHAASRHGHGHEHGFGPGHGH
                     GHGHEHAHGGPWQWGPPGGFGPGGGRPPWARGGGRGPWGRGRKAPKGNVRAAILALLAE
                     EPRNGYQIIQEINERSGEAWKPSPGAVYPALQQLADEGLITAEEGGGRRTYRLTAEGGA
                     YVAEHADELEEPWAQMAPDFGEGAPELFRQVAQTGAAVMQIVHSGTPDQVRRATEILSE
                     TRRALYRVLAGEEPRAGEEPRAGGADAGPTAGGPTAQGPGEEPA"
     misc_feature    complement(6950..6970)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            7000..8985
                     /locus_tag="KLI87_RS24660"
                     /old_locus_tag="KLI87_24660"
     CDS             7000..8985
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.5"
                     /locus_tag="KLI87_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24660"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_156215242.1"
                     /transl_table=11
                     /translation="MGTDEAMTAPDAVVTGGGAVARGRLRGELLLGMAVFGLYALVVML
                     PQDARERAARGHGRALYDLERALRLDVERTLNGWLAGQPVWRVLANYEYAITYIASAVA
                     LLAWLYLRHPERYRTARNAFLLINLVGIACFALYPVMPPRLMPELGFVDTVRLGRTWGS
                     WGSPMVEHADRFAAVPSLHMAWTLWVGVELARVSARRWVQSVNAVHILLTLYVIMATAN
                     HYLLDALAAVPLVGFAVYAAERATPRGAGERVRGPDAFFLAVETPEAPQHAGGLIVLDT
                     ARAPVTRDDLAALVAARLEDHPRFRQRLADGGRWRRPLWRDDPAIDWAWHVQERRVDGM
                     AGLRAVVAAIQSEPLPRDRPLWRMILVTGVAPGRDAVVFLMHHVVADGVGVVAHAMALM
                     EPYPLDYGGTGRRRRPVQEALATATGLGQLAADAARPARLPAAGTSERRFGTLLVPLDQ
                     ARDVARRHGARVTDVVLCAVAGGLHRVLRETPGAGDSCRVAVPLMMRSPGDGAEGNHTS
                     AVMIDLPIGKMPEADRLAETARRARVLRSGTRPLAAWFVMRQAGRVMPAPLHARFARYA
                     YSARFLQGIVSSLPGPDRLLRLAGAPLLEVYPVIPLAPGAPLAAGALGVDRDLCFGVCA
                     DPGLVDDADRMTAAVAEVVRELREAD"
     gene            complement(8996..9994)
                     /gene="hpnH"
                     /locus_tag="KLI87_RS24665"
                     /old_locus_tag="KLI87_24665"
     CDS             complement(8996..9994)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540959.1"
                     /locus_tag="KLI87_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24665"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_250904190.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-18, bitscore: 63.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.8e-09, bitscore: 30.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRQSLRVGGYILRNRLARRAKFPLLVELEPLYACNLACAGCGK
                     IQHPASLLKQRMPVEQAVAAVRESGAPMVSIAGGEPLMHPGIGEMVAELVAMKRYVFLC
                     TNAALIPKKIDLFEPSRYFAWAVHVDGLRERHDASVCKDGVFDQVVEAIAMCRERGFRV
                     TTNTTVFNTDTPQTVIDVLDYLNDDLGVDQMMISPAYAYEKAPDQEHFLGVQETRELFR
                     KVFADGRRRRWRFNHSPLFLDFLEGRADFPCTAWAIPSYSLKGWQRPCYLMDDGYADTY
                     EELVRTTNWGAYGRGRDDRCSNCMAHCGYEPTAVFATIGSLTESLRAIRSG"
     misc_feature    9994..10010
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     gene            complement(10001..11884)
                     /gene="shc"
                     /locus_tag="KLI87_RS24670"
                     /old_locus_tag="KLI87_24670"
     CDS             complement(10001..11884)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01507.1"
                     /locus_tag="KLI87_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24670"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_214618874.1"
                     /sec_met_domain="T2TS (E-value: 8.5e-144, bitscore: 475.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAEPAAPSTREAARRTLDAAREHLLGLQSPEGWWKGELQTNV
                     TMDAEDLLLREFLGVRDEEETREAARWIRSQQREDGTWANFFGGPPDLSTTVEAYVALR
                     LAGDPTGADHMRRAAAYVREAGGLPATRVFTRYWLALFGRWPWDALPVVPPEMIYLPSW
                     FPLNVYDFGCWARQTIVPLTVAAALRPVRPLPFDIAELHGQHVRRRRQGPPGWAEAFHA
                     LDRALRVYQRRPVKAVRRAALRRAAEWIIARQEPDGSWGGIQPPWVYSLIALNLLGHDV
                     DHPVMRRGLQGLERFTIRDGQGRRLEACQSPVWDTALAMTALADAGMPAGHPALEKAAA
                     WVVGEEVKGPGDWQVRRPGLPPGGWSFEFDNDYYPDVDDTAEVVLALGRVAHPDAPPAV
                     ERGLRWMAGMVSRDDGFGAFDADNTRELCRRLPFCDFGEVIDPPSADVTAHVVEALCAQ
                     GMGDSQLCKRAVVWLLKAQEQDGSWYGRWGANHVYGTGAVVPALIAAGVRPGKPAIRRA
                     VAWLERHQRDDGGWGEDLRSYRDPAWIGRGASTPSQTAWALLALLAAGERGPAVERGVG
                     WLTERQRPDGTWDEDHFTGTGFPGYFYINYHLYRLVFPVSALGRYLREDAS"
     gene            complement(11884..12876)
                     /locus_tag="KLI87_RS24675"
                     /old_locus_tag="KLI87_24675"
     CDS             complement(11884..12876)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634145.1"
                     /locus_tag="KLI87_RS24675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24675"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_250904243.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6e-62, bitscore:
                     204.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVRELVDGALRAAVGRLDPHTYRVAAYHLGWADAEGRPRKEPA
                     GKALRPALALLSARAAGAPPESALPGAVAVELTHAFSLLHDDIMDGDRTRRHRPAAWAV
                     YGEPAAILAGDALLALAGEVLLEAPGQGSARAARALAVATRHLIAGQSLDLSFETRHKI
                     TLEECQSMAAGKTAALLACSCSIGAVLDGAPEGLAAALEGFGADLGVAFQLTDDLLGIW
                     GDPAATGKPALSDLRSRKMSLPVVAALNSGTPASPALAELYARPEPPGEDELAEAARLV
                     DLAGGRAWARAEAARRVESAGEHLAGAGVPTPVRTEFLRVADFVTHRDH"
     misc_feature    12893..12908
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            complement(12894..14216)
                     /gene="hpnE"
                     /locus_tag="KLI87_RS24680"
                     /old_locus_tag="KLI87_24680"
     CDS             complement(12894..14216)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634146.1"
                     /locus_tag="KLI87_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24680"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_214618876.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-08, bitscore:
                     29.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 4.8e-11, bitscore: 38.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVVVVGGGLAGISAALALQEAGADVTLVEARPWLGGATHSFGRG
                     DLTVDNGQHVALRCCTAYQGLLQRLGTDHLLDVQRRFDVTVLRPGGAPARLRRAPLPSP
                     LHLLPALARYAPLSAAERLRAVWAAATIRSLDPADPVLDGVAAGTWLAERGQRPWAREA
                     LWGLFVTAALNAEVDDAALGLSAMVCRRALFGRADAADIGVPSVPLADLHGGPALARIE
                     EAGGTVLLKAKVEAVTADPKVIVDGAPIAADAVVMAVPHEAAARLLPAEALPDPLRWPE
                     LGASPIVNVHVVYDRPVLGLPFVAAVGSPVQWAFDRTVVGGLRGDGQYLAVSLSAADRW
                     IDVPTARLRERFTRELRRLLPAARHASVTDFFVTRERRATFRQRPGSGAARPGAATRAP
                     GLFLAGAWTDTGWPDTMEGAVRSGLTAARLVRRHLEGVRGR"
     gene            complement(14230..15147)
                     /gene="hpnD"
                     /locus_tag="KLI87_RS24685"
                     /old_locus_tag="KLI87_24685"
     CDS             complement(14230..15147)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540950.1"
                     /locus_tag="KLI87_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24685"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_156215248.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.3e-59, bitscore:
                     195.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3e-65,
                     bitscore: 215.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSETCERPEWVVEAYRHCERVVREEARNFGYGIRLMPAPKRRA
                     MSAIYAFARGVDDIGDGPEPACVRMDLLDRARGRLETVQEVLWRRADSRALEGHPVLTA
                     LADAAGRYPIPLDAFAELIDGCESDVRGAAYETFDDLLRYCQQVAGTVGRLSLGVFGYD
                     GRQRAEGLADSLGVAFQLTNILRDVREDRLAGRVYLPAEDLDRFGCTLELDETGEFVDP
                     ASRLHDLVAFQAERARAWYAEGLRLLPLLDRRSAACTAAMAGIYRRLLERIAESPALAL
                     TSRVSLPTWQKAVVAARALTGVER"
     misc_feature    15137..15148
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 14.92"
                     /tool="antismash"
     gene            complement(15203..16066)
                     /gene="hpnC"
                     /locus_tag="KLI87_RS24690"
                     /old_locus_tag="KLI87_24690"
     CDS             complement(15203..16066)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634148.1"
                     /locus_tag="KLI87_RS24690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24690"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_308166152.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-42,
                     bitscore: 141.5, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1e-40, bitscore:
                     135.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEPPWSAREHERGLDALARRENFPVAARLLPGRHRAHLRAVYG
                     FARLVDDIGDEAPGAHRVALLDSVDADLDLLYKGRAPVLPQLRRLAETVHARGIPQEPF
                     RRLVQANRQDQEVTRYASFDELLGYCVLSANPVGRIVLHVFGAEGRGLEEASDRVCTAL
                     QVIEHCQDVAEDFRAGRIYLPGEDLRRFGCAEDDLSRAVTPTRLRGVLALESNRARDLL
                     DRGAAPLMAGLRGWARIAVAGYVAGGRAALAALVRGRYDVLARTPRPRGPVLLANWASA
                     LGGGRR"
     misc_feature    complement(15806..15808)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16172..16186
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.84"
                     /tool="antismash"
     gene            complement(16210..17142)
                     /locus_tag="KLI87_RS24695"
                     /old_locus_tag="KLI87_24695"
     CDS             complement(16210..17142)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016533.5"
                     /locus_tag="KLI87_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24695"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_214618878.1"
                     /sec_met_domain="APH (E-value: 3.4e-08, bitscore: 29.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPILPGPLPSVLVENAVEVWGDDGRRWLKRLPGLLAEIAREWRL
                     EIEAARYGLSYHWVAPVRREDGTKAVLKLGPPEPGHLGIEAAALEIYGGEGAVRLLEHD
                     PGRGALLLERAEPGRVLSELVPDRDEEATAVFLDVARRLRHVPPLGCALPGLEKESASF
                     SGHLRRFPGDGPLPRHLVERAGRLFDELCASAPERLVLHGDLHHDNILSAEREPWLAID
                     PHGVVGDPGYEAGVLFYNPGPDDRDGRLVDLVPARIEQVADGLAMPVERVVAWGFVMAV
                     LSEVWTAQGDGTPGSRALDVALSLVGRLP"
     gene            17200..20760
                     /locus_tag="KLI87_RS24700"
                     /old_locus_tag="KLI87_24700"
     CDS             17200..20760
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019334.5"
                     /locus_tag="KLI87_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24700"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_214618879.1"
                     /sec_met_domain="Pkinase (E-value: 2.4e-40, bitscore:
                     134.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPLVPGDPRELGDYWLARRLGAGGQGVVYEAYGADGARVAVKA
                     LHGVFAGERAGGPRDVLAREIDAVTRVSPFCTARVLAFDLDAEPPYVVSEYVPGPDLER
                     AVASGGPFGSGELGRLAIGVATALVAIHRGGVVHRDLKPGNVLLGPDGPRVIDFGLARA
                     EDMTRSATGAKGTPRYMSPEVFAGEPASAASDVWAWGAVVLFGALGRPPFAGENLMQLS
                     HTVQHVEPELHVLDEPLRSVVAAALAKRPRDRPSAREVLLDLLGGSFDEGAMLSEGSRV
                     AAAAVAGAAPPSLADVAEAAYRRLDPLAREAVPAILLRMVLPGEGAADTLRRAAVDEFG
                     DGAERAVEEFTRAGLLVREGDRVAICGAALLRAWPRLRGWVDDERAGLAVHRSLADAAR
                     VWDRHGRRAGDLLQGSVLARAVQWAATGRRHLTLNAVERAFLDASAALGRRRARSRGAL
                     TAVLAVLLVVAVGGAVVAVNQRAVLSRQRDRAIADRLAALAASLQRDDPRTSRRLALAA
                     ARVGDDDQTRKALINAMYQWEGDTFNPASNAQVVLTPDGRTATFDDRVQVTRWDLKTHQ
                     RVPMPPGAEPKSAAVFSPDGRHMAQLLSTGGDLSRRGVVQVYDAATGKPQGRPMGDPRQ
                     SFWNLRYSVSGNLLMMDNGPGGSGDPRTTAPEMALWNARSGRLAMSWKERPYAWAVSAD
                     DALVAMVLPSGFQLWDVAARKRIPTPWLGAALASESASQRIRQVGFGPAGARLALVVGS
                     RVTVLDLNNLARTEPVASRSRVPWHERSARGVDEPVFSPDGRLLAVGFTLWNLDGSAEA
                     PLMARGLDDETPTDCRFSAAGDLLRCATTLNRVVTTNISGYADRISVGRDAGHGVLSPS
                     GDLLASMGADSVSITGNPAGWTSPISVPSLRSVWRGMVFSPDGGLVAIPDRNPDDGFGV
                     WDARTLQKVAELDWPDGALGKGVAFSPDGRSLVGGLNAEVIDPRHPYKSWLQEWDARSG
                     RRTRVIPLESSGSGELFYRSDGRTVTLKSAVVDMDSGQVHKRFDFFSVVDVLAVSPDGS
                     VALVIINPDDLYLWDLRGDKRRGTPLAAVPDVEDLPAAFSPDGRLVATSDARGGVHLYE
                     VATGRPYGPTLPGHAGGVDTFAFSRDGTVLYTYGGDRTIQATTLDPARLTDRLCAQVGG
                     LSEAEWNQYVPDLSYRPVCG"
     misc_feature    19006..19008
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19207..19209
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21148..23013
                     /locus_tag="KLI87_RS24705"
                     /old_locus_tag="KLI87_24705"
     CDS             21148..23013
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00976.1"
                     /locus_tag="KLI87_RS24705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24705"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_214618880.1"
                     /transl_table=11
                     /translation="MRARRRTTWANRRSRSWRLSLVAAAVVLLAGVAAPGAPADAAPKA
                     EVCEFSVQKDVPATMRDGTVLRSNVFTPKGDGKFPVILMRLPYNKEGALSFVYGAPDRY
                     AKACYLVVVQDVRGEYKSDGAFYPYRTEAEDGYDTIEWSAALPHSNGKVGMYGFSYPGL
                     TQWLPATLTPPHLVTIAPAFTSSDIYDGWTYEGGALYQAFIQDWLLSFLNGGVISKLPD
                     AAKLRAEMTQASRDLHTKWYRHQPLNNFPPLYPGDNRIAPYYFDWIDHPSDDDYWKRWS
                     IRTKYPRVNVPSLNFGGWSDIFLNGTVENFAGMRAQGGSEVARQGSQLLVGPWTHGGSG
                     RTVGAVDFGPEAVVAVGDLHLRWFDHWLKGIANGVDADPPVKVFVMGANKWRTADSWPI
                     PGTANTTYYLHSKGDANTANGGGTLDSTAPATGEKADQYQYDPANPVPSVGGRFQSSVP
                     GGPQDQRSVEQRRDVLVYSTPRLTKDTEVTGPISVTLYARSSAKDTDWTAKLTDVQPDG
                     TSMLVRDGIQRARYRVSLEKPELITPGEVYKYTIKLWPTSNVFKAGHRIRLEISSSNFP
                     MYDRNPNTGGKFGADTTTQPASQTVLHDPEHPSSITLPIIPVPVR"
     misc_feature    21166..21181
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     gene            complement(23120..23767)
                     /locus_tag="KLI87_RS24710"
                     /old_locus_tag="KLI87_24710"
     CDS             complement(23120..23767)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601542.1"
                     /locus_tag="KLI87_RS24710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24710"
                     /product="response regulator transcription factor"
                     /protein_id="WP_156215255.1"
                     /transl_table=11
                     /translation="MSVRVLVADDQPIVRTGLTMLLDAQPGIEVVGAAADGREAVRLAL
                     RLRPDVGLFDIRMPLMDGIEATRRLAGPDVTDPLPIVVITTFDLDEYVYGALKAGARGF
                     LLKDAGPALLTQAIHAAADGDALIAPSVTVRLLAAFAHAQTPPRRQPIEPLTAREEEVL
                     VPVAQGRTNNEIAGELHITPSTVKAHVASLMRKLGARNRVEVAMWAHETGRI"
     gene            complement(23767..24915)
                     /locus_tag="KLI87_RS24715"
                     /old_locus_tag="KLI87_24715"
     CDS             complement(23767..24915)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017578697.1"
                     /locus_tag="KLI87_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24715"
                     /product="sensor histidine kinase"
                     /protein_id="WP_214618881.1"
                     /transl_table=11
                     /translation="MATNALRSLWAEPRPANAPALGPRDWALVAVLICWSAAEAVLRQD
                     LAPRPLLLLAVLAVLGPLLWRRTHPLVAVVVSFGTLTIIDVVRVLTGTQGALLNSGIAV
                     LILAYALFRWGSGREAASGLGVILLWPALITALGADPTTLAEVVAGYAFFLFAAALGTA
                     IRYRTKIRIRDIDHAKAREREQLARDLHDTVAHRVTGIAIQAQAGRAVAASHPERAVEA
                     LAVIEDAASRTLTELRAIVGVLRATQDTGFAPQPGVAEVEQLATDGRTRPCVKVTLSGE
                     FDDLSPAVGTAIYRLAQESVTNARRHARHASKVTVAVTGDADQVRLTVDDDGSAAGGRA
                     PAGYGLVGMRERASLLGGTFHAGPAAERGWRVEAVLPRTGTP"
     gene            25073..25585
                     /locus_tag="KLI87_RS24720"
                     /old_locus_tag="KLI87_24720"
     CDS             25073..25585
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039408.4"
                     /locus_tag="KLI87_RS24720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_24720"
                     /product="DUF6326 family protein"
                     /protein_id="WP_214618882.1"
                     /transl_table=11
                     /translation="MRTPQSQTAPENPSSQSTLEDLRLPVQAKLAAAWTSFMFLYIYVD
                     YLALYKPGFLDDLLGGTVHEFDTGPTFVAVALSLMAVPILMILLSATLPARVNRTINVV
                     VAALYIPVSVFNAAGEPWSYSYFYGLSIGLELLLLAFILRSAWSWPRRITSPATLATTL
                     DSEPQQA"
     misc_feature    complement(25781..25794)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
ORIGIN
        1 ccggctgcac gccccggctc caggcggcga tggtcgcgac gggcctgccg ttcctgcccg
       61 gcgtcgccac cgcgtccgag gccgtcgcgc tgctggaggg cgggatcacg gcgatgaagt
      121 tcttccccgc cgaggcggcg ggcggccgcg cctacctgaa ggcgctcggc ggcccgctgc
      181 cggacgcccg gttctgcccg accggcggcg tcacccccgg caacgccgcc gactacctcg
      241 cgctgccgaa cgtcggctgc gtgggtgggt cgtggctgac gccgggcgac gccgtccgcg
      301 cgggcgactg ggaccggatc cgcgcgctcg ccgccgacgc cgccgccctc gggaagggct
      361 gacccctctg ccggcgggcc cctacttcgg cgggtggccg tgggcgcagg gtccggcggt
      421 gagtcgcggg gccgagccgt gcgggacgag gtccatccgc agccgcccgc aggcgcagcg
      481 gctccagatg acggttcctt cgctggtcag atggcgggag agggtgctgt tccgctggtt
      541 catgcgacca gtctcccgcc gccgaacgtg cgcgtctatt tcacgttttc ggatctgatc
      601 atgcaatatg gtgacatgat tgatctgcgg cggctgcacc tgctccggct cgtccaccag
      661 tacgggacgg tcacggcggc ggcggaggcg atgcacctca cgccgtcggc ggtctcccac
      721 cacctgcgcg agctggcgcg ggagctgggg gtggtgctgc tggagccgca gggccgccgg
      781 gtgcggctca ccccggcggc gcacctgctg atcgggcacg cggacgcgct gcacgcccgc
      841 tgggaggagg ccctctccga cctggagtcg caccgcgccg gggccgccgg gccgctgcgc
      901 atgtgcgggt tcacgacggc ggtcagcggg ctgatcgccc cggccgccgg gaggctgacg
      961 gccgccgacc ccgatctggc gatcgagatc cgcgagtgcg acaccgacgt cgcgatgggc
     1021 ctgctcgccg ccggggagac cgacctcgcc gtgatcgagc ccaccccgga ggcaccgccg
     1081 cccggcgacc cgcgcttcga ccgggagccg ctgctggagg aggccctcga cctgatcgtc
     1141 ccggtcgggc atccgctcgc gcggcgcggc acggccgtgc tggaggacgc ggcgtccgag
     1201 gcgtggatca gcgtcgagcc cgacggctgc gcccaccacc agcaggtgat gacctactgc
     1261 gccgccgccg ggttcacgcc ccggatcgcc cacaacgcca cgacctggtc ggtgatctgg
     1321 gcgctggtcg ccaacggcct cggcgtgtcg ctggtgccga ggctggccga cgggcagtcc
     1381 ggccagaccg tcgtccgggt gccgctgacg ggcgactccg tcccgaagcg gcgggtgctg
     1441 acgtgcgtcc gccgggggag ccgcacccac ccgctgatcg cccgcggcct ggccgcgctg
     1501 cacgaggccg tccccgccca atgcgatctc ctccccgccg cgacccgggc cgttcccgtc
     1561 gcgagctgag cctcagtcgg tcgcgatcgc ctggaggatg tccaggcgcg cggcgcgggc
     1621 ggcgggccac acggcggcga ccacgccgat ggccgcggcg gccgcgacgc acagcgcgag
     1681 gcgcccgtag gggacggcga gcacctccat gccgtcctcg ccgcccgcga tcgccttctg
     1741 caggacgacg ccgagcacgc tcccggtccc gacgccgagc accgcgccga acagcgacac
     1801 cacgacggcc tcgtagcgga tcatgcggcg gagctggcgg cgctgcgtgc cgaccgcgcg
     1861 cagcagcccg atctcccgcg tccgctcggt gaccgcgagc gcgagcgtgt tgacgatgcc
     1921 gagcgcggcg accagcaccg acagcaccag cagcccgagg accagcgtga ggaacaggtc
     1981 gatctcgccc gccgcgtcgt ccttgacctg cgcgcggtcc ttcagctcca ggttcggcca
     2041 cggcgcgagc gccgactcca gcgccgcccg ccgggcaccc gcgaccgtga cctcgatgcg
     2101 ctcgatcggc gcgtccgggt cgtgggcgcg gtacccggcc cagtcgatga tcaccgtggg
     2161 cgcggacggg gtgagcgccg gccggtcggc gtagatcccg gcgatgcgga acgtccgcct
     2221 cgtcccgtcc tggtactcgc cggggagcgt gccgccgatc ctccagccgc ggtcgcgggc
     2281 gacgctgcgg ccgaccagca ggtcctcccc gcgcacggcc gccgagccct cctggagcgg
     2341 cagccggaag tgggccagca gctcgcccgg cgaaccggcg gtcgcggcct gcacggcgcc
     2401 ctccagccgg aaccgggccg tccggaccgg gatcgccgcg cggacgcccg ggacgcggcc
     2461 caccgccgcc gccgcgcccg cctcgaccgg cgtgacctgg ctgcgcccgg tgacctggta
     2521 gtcggcggtc agcgcggcct ccagctgccg gtcgaccgag gccgccaacg actggacgat
     2581 gatcgacacg gtcgcgatga gcgccagccc gatcgtcagc gccgacgccg tcgccgacgt
     2641 ctgccggggg tcgcggaccg cgttgcgggc gcccatccgt ccggcgccgc cgccgaaccg
     2701 cgcgaacggg cgggcgagga cgcgggcgac cgggcggctc agcgcgggcg agaccaccac
     2761 gacgcccgcg aacagcagcg ccgcgccggt tccggcgagc gtgaggccgg acgtcccgtc
     2821 ccccgcgagc ccggccgcgg ccaggatccc gccgaccgcc agcaccgcgc atccgccgag
     2881 gacgcggcgc cgcagcgggc ggggcggcgc cgcgtcctcc cgcagcgccg cgaccggcgg
     2941 gatccgcgcc gcgcgccgcg ccgggacgaa cgctgcggcc agcgccaccg gcgtccccac
     3001 caggtaggcg gcgaggacgg cggacgcggg cagcgcgagc ggcccgaacg gcagctcctc
     3061 cccgccggtg accagcgtca tcagcctggc gagcccgagc gcgaccacgg cccccgccgc
     3121 gaggccgagc gtcgagcccg ccaggccgac cacggccgcc tcgccgagga tcgagcgcgt
     3181 cacctgcccg cgcgaggccc cgacggcgcg cagcagcgcc agctcccgga cccgcccgcc
     3241 gaccagcatc gcgaaggtgt tgaagatgat gaacgacccg acgaacaccg cgatcagcgc
     3301 gaagaccagc aggaacgtgc gcatgatctt gatgatgtcc ttgagcgggc cggcctgctc
     3361 ggccgccgcc tccgccccgg tgacggcctc gacgcccggc gggaggacgg cggcgaccgc
     3421 gtcccgcagg cgctcctggg tgacgccgcc gtccgcgtgc acgacgatgc gctcgtaggt
     3481 gccgggacgc tgcccgagca ggcgcggcgc ggcgtccggc gcgaacgcgg tcatcgagat
     3541 cgaggagccg agcgcggagt cgccgacccg gaacaggccg gtcagccgga acgtccgcgt
     3601 gccggaccgc aacgcgaccg tcacccggtc gccgacccgg tagcgggcgt cgcgggcggt
     3661 ggtggcgtcc atggcgacct cgtccggcgc gcgcggcggc gccccggcgg tcaggcgggt
     3721 cagcgacagg tcgcggtcgc cgctccacgc caccccggtc tgcggctccg ccccggcgat
     3781 cctcccctgc cggtcgacgg cggccgcgaa cccggtgatg acgccctccg ccttcgcgac
     3841 accgggcgcc cgccggacgg ccgcgagcgc cgacgcgggc accggacgcg gcgccgcgcg
     3901 ctcgcccggc cccgtccgga acgactgccg cgccctgacg accgtgtccg tcccgcgccc
     3961 gaggtcgtcg aaggcgcggt cgaacgagcg gctcagcgtg gccgagaaga tcagcgtgcc
     4021 ggagacgaac gcgacgcccg cgacgaccgc caccaccgac agcagcaggc gggcgcggtg
     4081 cgcggccagc ccacggaata cgagcttcac catcatggcc acgattcgac cggtgcggtg
     4141 cggggccgcg gcagggcgca tcgtcgcgtc cgcgtccggg cggcgcacga cgcacggcag
     4201 gccggacccg actttcgtag gggtccccgg cgggggaggg gtgcgtacgg tgggcccgtg
     4261 cgcctcacac cgccgcccgc gccccccgga cgcgacctcg ccgccgacgc cgtggccgtg
     4321 gtgtgcgcgc tggcgctgag cctccagacg gcggcgggcc ccgactcggt cctgcgcggc
     4381 caccacggcg cgacggccgc ggtggtggcg ctccccgcgc tcgcgctggc ggtccgccgc
     4441 cggttcccga tgacggtcgc gtggctcacc gcggcggtcg ccgcgctgct ggacgccgtc
     4501 gagcgcctcg cgcccggcac gctgctgcgc gacggcccgc ccggcgcgtt cgacccgatc
     4561 gtgtggtggc cgcccgcgct gccgttcgcc gtctacgccg cgatggcctt cccccgcgac
     4621 ggggaccggc ccgtctgggc gcgggcgctg ccggtcgtcg cgctcgtccc gctggtcggc
     4681 ctcacccagg acgtgatccc cgacgagtcg atcaggcgcg tctcggggca ggagacgtcc
     4741 tcggtcgaga cgatggtctt ccggagcatg gcgatgctgg tcgcggcggc gctgctcggc
     4801 atgtacgcgg cggcgcggcg ccgcgtcctg caggggctga ccgagcgggc cgagcgcgcc
     4861 gagcgggagc ggcacctgct cgccgagcgg gcgcgggccg aggagcgcgc ccggctcgcc
     4921 gccgagatgc acgacgtcgt cgcgcaccgg gtgacgctga tggtgctgcg cgcgggcgcg
     4981 ctgcgggtca gggcgcccga cgaggagacc cgcgtcgccg ccgaggagct gcgcgacgac
     5041 ggctgccacg cgctggagga gctgcgcgac gtcatcggcc tgctgcggcg cggcgccggg
     5101 gcggcgggcg cggcccccgc ccccgcgtcg gggccgctac ccgacctgtc ggcgctggtc
     5161 gccgagtccg ccgccgtcgg cgtccgggtc gagctggtgg agcgcgggga gcccgcgccc
     5221 gcctcgcccg ccgtcgggcg caccgcctac cgggtcgtcc aggaggcgct gaccaacgcg
     5281 cgcaagcacg cgccgggcgc cgccgtccgg gtggaggtcg gctaccgctc cgacggcgtc
     5341 cggctgagcg tgctctgcgc cgccccggaa cgggacccgg acgcggcgct cgcggccagc
     5401 ggctccggga cgggcctcgc cgggctccgc gagcgcgtcg agaccgtcgg cggcaccttc
     5461 agcgcgggcc cggccgggga cgggttccgc gtcgaggcgt cgctgcccgc ctacgtcccc
     5521 ctcccgacgc cgcccgcgcc ctgacggtgc gcgtggtggc ggaggtgccg gtgcccgaac
     5581 gccatcagga gggcccgcac cgcccagacc gccagcgcca cctggaggac gaccaggaac
     5641 cccgggcccg gccccatcgt gaacgccagc accaggaaca gcccgagcag cagcgggaac
     5701 ggcggcccgt gacggtggcg gccatggtgg tggccgaggt ggtggtggcc gaggtggtgc
     5761 ggccggcccc ggtggtggtg acgcgcgggc gccgcctccg gcaccgccag gccctgcggg
     5821 tcgggcaggt cgaggacgac cgcccgcagg tcgccccgcg tccgggccgc cagcgtcgtg
     5881 ccgagccgct cgtcgagttc ctcgcggtcg agccgtccgg ccgcgaagtg gtcgtgcagg
     5941 gcgaccatga ccgcgtcgcg ctcggcgtcg ccgacgcgga cgtcgccgga gcggatcccc
     6001 tcgggggtcg tcacgccggc tcctcacccg ggccttgggc ggtggggcct ccggcggtgg
     6061 ggcccgcgtc ggccccgccc gcgcgcggct cctcgcccgc gcgcggctcc tcgccggcga
     6121 ggacgcggta cagggcgcgc cgggtctcgg agaggatctc ggtggcccgc ctgacctggt
     6181 ccggcgtccc ggagtggacg atctgcatca ccgccgcgcc cgtctgcgcg acctgccgga
     6241 acagctccgg cgcgccctcg ccgaagtcgg gtgccatctg cgcccacggc tcctccagct
     6301 cgtcggcgtg ctcggccacg taggcgccgc cctcggccgt gagccggtag gtgcggcggc
     6361 cgccgccctc ctcggcggtg atcagcccct cgtccgcgag ctgctggagc gccgggtaga
     6421 ccgcgccggg gctcggcttc cacgcctcgc cgctgcgctc gttgatctcc tggatgatct
     6481 ggtagccgtt gcgcggctcc tcggcgagca gggcgaggat cgccgcgcgg acgttgccct
     6541 tgggcgcctt gcgcccccgt ccccacgggc cgcgcccacc gccgcgcgcc cagggcgggc
     6601 gtcccccgcc gggcccgaag ccgccgggcg ggccccactg ccagggcccg ccgtgcgcgt
     6661 gctcatggcc gtgcccgtgc ccgtggcccg gcccgaagcc gtgctcatgc ccgtgcccgt
     6721 gccgggacgc cgcgtgcgcg gccttcgcgc cgatcgccgc cgccgcgaac gcccagcgcc
     6781 agtcgggccc gctccgatgc gtcgctccca tggtcaccac caccttctga gatctctcta
     6841 tgatctctcg cgataggaca acgatatatc gaagacgtac ggttcgggaa gatggttccc
     6901 gcgaaaaccg ggcccccggc gcgtcgcgcg ggtccgccgg atccgggcat ggtcgtctga
     6961 ccggcggaaa tcctgggtaa ccacccctgt ggggggacga tggggacgga cgaggcgatg
     7021 accgcgccgg acgcggtcgt gaccgggggc ggcgcggtcg cgcgcgggcg cctgcggggc
     7081 gagctgctgc tgggcatggc ggtcttcggc ctgtacgcgc tggtcgtgat gctgccgcag
     7141 gacgccaggg agcgggccgc tcgcgggcac ggccgcgcgc tctacgacct ggagcgggcg
     7201 ctgcggctgg acgtcgagcg gacgctgaac ggctggctcg ccgggcagcc ggtctggcgc
     7261 gtgctggcca actacgagta cgcgatcacc tacatcgcga gcgcggtcgc gctgctcgcc
     7321 tggctgtacc tgcggcaccc ggagcgctac cggacggcgc gcaacgcgtt cctgctgatc
     7381 aacctggtcg ggatcgcctg cttcgcgctg tacccggtga tgccgccgcg gctgatgccc
     7441 gagctcgggt tcgtcgacac ggtccggctg ggccgcacgt gggggtcgtg gggctcgccg
     7501 atggtcgagc acgccgaccg gttcgcggcc gtcccgtccc tgcacatggc ctggacgctg
     7561 tgggtcggcg tcgagctggc ccgggtgtcg gcgcggcggt gggtgcagtc ggtgaacgcg
     7621 gtccacatcc tgctgaccct gtatgtgatc atggcgaccg ccaaccacta cctgctggac
     7681 gcgctggcgg ccgtcccgct ggtgggcttc gcggtgtacg ccgccgagcg cgcgaccccg
     7741 cgcggcgcgg gcgagcgggt ccgcgggccc gacgcgttct tcctggccgt ggagaccccg
     7801 gaggcgcccc agcacgccgg ggggctgatc gtcctggaca ccgcgcgggc gccggtgacc
     7861 cgcgacgacc tggccgccct ggtcgccgcg cggctggagg accacccgcg gttccggcag
     7921 cggctcgccg acggcggccg gtggcggcgg ccgctctggc gcgacgaccc ggcgatcgac
     7981 tgggcgtggc acgtccagga gcgccgcgtg gacggcatgg ccgggctgcg cgccgtggtc
     8041 gccgcgatcc agtccgagcc gctgccccgc gaccggccgc tgtggcggat gatcctggtg
     8101 accggggtcg cgccgggacg cgacgcggtc gtgttcctca tgcaccacgt cgtcgccgac
     8161 ggcgtcgggg tcgtcgcgca cgcgatggcg ctcatggagc cctacccgct cgactacggc
     8221 gggacggggc gccgccgcag gcccgtccag gaggcgctcg cgacggcgac cgggctcggc
     8281 cagctcgccg cggacgcggc gcgccccgcg cggctgcccg ccgccgggac gtccgagcgc
     8341 cggttcggca ccctgctcgt cccgctcgac caggccaggg acgtcgcgcg gcggcacggc
     8401 gcgcgggtca ccgacgtcgt gctgtgcgcg gtggcgggcg ggctgcaccg ggtgctccgc
     8461 gagaccccgg gcgccggcga ctcctgccgg gtcgcggtgc cgctgatgat gcgctcgccg
     8521 ggcgacggcg cggagggcaa ccacaccagc gccgtcatga tcgacctgcc gatcggcaag
     8581 atgcccgagg ccgaccggct cgccgagacc gcccggcgcg cccgcgtgct gcggtcgggg
     8641 acgcgcccgc tcgccgcctg gttcgtgatg cgccaggccg ggcgggtcat gcccgccccg
     8701 ctgcacgccc gcttcgcccg ctacgcctac agtgcccggt tcctccaggg catcgtgtcg
     8761 agcctgccgg gccccgaccg gctgctgcgg ctggcgggcg ccccgctgct ggaggtctac
     8821 ccggtgatcc cgctggcgcc cggcgcgccg ctcgcggccg gggcgctcgg cgtcgaccgc
     8881 gacctgtgct tcggcgtctg cgccgacccc ggcctcgtgg acgacgccga ccggatgacg
     8941 gccgccgtcg cggaggtcgt ccgcgaactc cgcgaggccg actagccccg gcgggtcagc
     9001 cgctgcggat cgcgcgcagc gactcggtca gcgacccgat cgtggcgaag acggcggtcg
     9061 gctcgtagcc gcagtgcgcc atgcagttgg agcagcggtc gtcgcggccc cggccgtagg
     9121 cgccccagtt ggtcgtccgc acgagctcct cgtaggtgtc ggcgtagccg tcgtccatca
     9181 ggtagcaggg gcgctgccag cccttcagcg agtaggacgg gatcgcccac gccgtgcacg
     9241 ggaagtcggc cctgccctcc aggaagtcca ggaacagcgg cgagtggttg aaccgccagc
     9301 ggcggcgccg gccgtcggcg aacaccttcc ggaacagctc ccgcgtctcc tgcacgccga
     9361 ggaagtgctc ctggtcggga gccttctcgt aggcgtacgc gggggagatc atcatctggt
     9421 cgacgcccag gtcgtcgttg aggtagtcga ggacgtcgat gacggtctgc ggggtgtcgg
     9481 tgttgaacac ggtcgtgttc gtcgtgaccc ggaacccgcg ctcgcggcac atcgcgatgg
     9541 cctccacgac ctggtcgaac acgccgtcct tgcagacgga cgcgtcgtgc cgctcgcgca
     9601 gcccgtccac gtgcaccgcc cacgcgaagt accgggacgg ctcgaacagg tcgatcttct
     9661 tcgggatcag ggcggcgttc gtgcacagga acacgtaccg cttcatcgcg accagctcgg
     9721 cgaccatctc gccgatcccc gggtgcatca gcggctcgcc gcccgcgatc gacaccatcg
     9781 gcgcgccgct ctcgcggacc gccgcgaccg cctgctcgac cggcatccgc tgcttcagca
     9841 ggctcgccgg atgctggatc ttcccgcacc ccgcgcaggc gaggttgcac gcgtacagcg
     9901 gctccagctc gaccagcagc gggaacttcg cgcggcgggc gagcctgttg cgcaggatgt
     9961 agccgccgac ccgcaggctc tggcgtagtg gcatgcccat ttacgacgcg tcctccctca
    10021 ggtagcggcc gagggcgctc accgggaaca ccagccggta caggtggtag ttgatgtaga
    10081 agtagccggg gaacccggtt ccggtgaagt ggtcctcgtc ccaggtcccg tcggggcgct
    10141 gccgctctgt gagccagccg acgccgcgct cgaccgccgg tccgcgctcg ccggcggcca
    10201 gcagcgccag cagcgcccac gcggtctggg acggggtgga cgcgccgcgt ccgatccacg
    10261 ccgggtcgcg gtaggagcgc aggtcctcgc cccagccgcc gtcgtcgcgc tggtgccgct
    10321 ccagccaggc caccgcccgc cggatcgccg gcttgccggg ccggacgccc gccgcgatca
    10381 gcgcgggcac gacggcgccg gtcccgtaga cgtggttggc gccccaccgc ccgtaccagg
    10441 agccgtcctg ctcctgcgcc ttcagcagcc acaccacggc gcgcttgcac agctgcgagt
    10501 cgcccattcc ctgcgcgcac agcgcctcca cgacgtgcgc ggtgacgtcg gcggacggcg
    10561 ggtcgatgac ctcgccgaag tcgcagaacg ggagcctgcg gcacagctcg cgggtgttgt
    10621 cggcgtcgaa cgcgccgaac ccgtcgtcgc gcgagaccat cccggccatc cagcgcaggc
    10681 cccgctcgac ggcgggcggc gcgtccggat gcgcgacgcg gccgagcgcc agcacgacct
    10741 cggcggtgtc gtcgacgtcg ggatagtagt cgttgtcgaa ctcgaacgac cagccgccgg
    10801 gcggcaggcc ggggcggcgc acctgccagt cgccggggcc cttcacctcc tcgccgacca
    10861 cccacgcggc ggccttctcc agcgccgggt gcccggcggg catgcccgcg tcggcgagcg
    10921 cggtcatggc gagcgcggtg tcccagaccg gggactggca cgcctccagg cgccgcccct
    10981 gcccgtcccg gatcgtgaag cgctccaggc cctggagccc gcgccgcatg accgggtggt
    11041 cgacgtcgtg gccgagcagg ttcagcgcga tgagcgagta cacccacggc ggctggatgc
    11101 cgccccacga cccgtccggc tcctgccgcg cgatgatcca ctcggcggcg cggcgcagcg
    11161 cggcccgccg caccgccttc accgggcgcc gctggtagac gcgcagcgcg cggtcgagcg
    11221 cgtggaacgc ctcggcccag ccgggcggcc cctggcgcct cctccgcacg tgctggccgt
    11281 gcagctcggc gatgtcgaag ggcagcggcc ggacggggcg cagcgccgcc gccaccgtca
    11341 gcggcacgat cgtctgccgc gcccagcacc cgaagtcgta gacgttcagc gggaaccacg
    11401 acggcagata gatcatctcc ggcgggacga cgggcagcgc gtcccacggc cagcgcccga
    11461 acagcgccag ccagtagcgc gtgaacacgc gcgtcgccgg gaggccgccc gcctcgcgca
    11521 cgtacgcggc ggcgcggcgc atgtggtcgg cgccggtcgg gtccccggcg agccgcagcg
    11581 cgacgtaggc ctcgaccgtc gtggacaggt cgggcgggcc gccgaagaag ttcgcccacg
    11641 tcccgtcctc gcgctgctgg gagcggatcc agcgggccgc ctcccgcgtc tcctcctcgt
    11701 cgcggacgcc gaggaactcg cggagcagca ggtcctcggc gtccatggtc acgttcgtct
    11761 ggagctcgcc cttccaccag ccctcggggg actggaggcc gagcaggtgc tcccgcgccg
    11821 cgtcgagcgt cctgcgcgcc gcctccctgg tggagggggc ggcgggttcg gctgtcgtgg
    11881 tcatcagtgg tcccggtggg tgacgaagtc ggcgacgcgc aggaactcgg tgcggacggg
    11941 ggtgggcacg cccgctccgg cgaggtgctc cccggcgctc tccacccggc gcgcggcctc
    12001 ggcccgcgcc cacgccctgc cgcccgcgag gtcgacgagc cgcgccgcct cggccagctc
    12061 gtcctcgccc ggcggctccg gccgggcgta cagctcggcc agcgccgggg acgcgggcgt
    12121 gccggagttc agcgccgcca cgaccggcag cgacatcttg cgggaccgca ggtccgacag
    12181 cgcgggcttg ccggtcgccg ccggatcgcc ccagatgccg agcaggtcgt cggtgagctg
    12241 gaacgcgacg ccgaggtcgg cgccgaaccc ctccagcgcg gccgcgaggc cctcgggcgc
    12301 cccgtccagc acggcgccga tcgagcacga gcaggccagc agcgcggcgg tcttcccggc
    12361 cgccatcgac tggcactcct ccagcgtgat cttgtggcgg gtctcgaagc tcaggtcgag
    12421 cgactggccc gcgatgaggt gccgggtcgc gacggccagc gcgcgcgccg cccgcgccga
    12481 cccctggccc ggcgcctcca gcagcacctc cccggcgagg gcgagcagcg cgtccccggc
    12541 caggatcgcg gcgggctcgc cgtagacggc ccacgccgcc gggcggtgcc gccgcgtccg
    12601 gtcgccgtcc atgatgtcgt cgtgcaggag cgagaacgcg tgcgtcagct cgaccgcgac
    12661 cgcgcccggc agcgcgctct ccggcggcgc gcccgccgcg cgggccgaca gcagggccag
    12721 cgcggggcgc agcgccttcc cggcgggctc cttgcgcggc cgcccctccg cgtcggccca
    12781 gccgaggtgg taggccgcca cccggtaggt gtgcgggtcg agccgcccga ccgcggcgcg
    12841 cagcgccccg tcgaccagct cgcggacatc ggtcatcgag accggaacgg tcgtcaccgg
    12901 cccctcaccc cctcaaggtg gcggcggacc aggcgtgcgg cggtcagacc gctgcgcact
    12961 gctccctcca tcgtgtcggg ccagcccgtg tcggtccacg cgccggcgag gaacaggccc
    13021 ggcgcccgcg tcgccgcgcc gggacgcgcc gcgccgctgc cgggacgctg gcggaacgtc
    13081 gcccgccgct cccgcgtgac gaagaagtcg gtgacggacg cgtgccgggc ggcgggcagc
    13141 agccggcgca gctcgcgcgt gaaccgctcg cgcagccggg ccgtcgggac gtcgatccag
    13201 cggtcggccg ccgacagcga gacggccagg tactgcccgt cgccgcgcag cccgccgacc
    13261 accgtccggt cgaacgccca ctggacgggc gagccgaccg ccgccacgaa cggcagcccc
    13321 agcaccggcc ggtcgtagac gacgtgcacg ttgacgatcg ggctcgcgcc cagctccggc
    13381 cagcgcagcg ggtcgggcag cgcctcggcg ggcagcagcc gcgccgccgc ctcgtgcggc
    13441 acggccatga ccaccgcgtc ggccgcgatc ggcgccccgt ccacgatcac cttcgggtcg
    13501 gcggtgaccg cctccacctt cgccttgagc aggacggtgc cgcccgcctc ctcgatccgc
    13561 gccagcgcgg gcccgccgtg caggtccgcc agcgggacgg acgggacgcc gatgtcggcc
    13621 gcgtccgcgc gcccgaacag cgcccgccgg cacaccatcg ccgacaggcc gagcgccgcg
    13681 tcgtccacct cggcgttcag cgcggccgtg acgaacagcc cccacagcgc ctcgcgcgcc
    13741 caggggcgct ggccccgctc cgccagccag gtgcccgccg ccaccccgtc caggacgggg
    13801 tcggccgggt cgagggaccg gatcgtcgcc gccgcccaca ccgccctcag ccgctcggcc
    13861 gccgacagcg gcgcgtagcg ggccagggcg ggcagcaggt gcagcgggct cggcagcggc
    13921 gcccgccgca gccgcgcggg cgccccgccg ggccgcagca ccgtcacgtc gaacctgcgc
    13981 tgcacgtcca gcaggtggtc ggtgcccagg cgctggagca gcccctggta ggcggtgcag
    14041 cagcgcagcg cgacgtgctg gccgttgtcg acggtcaggt cgccgcgccc gaacgagtgg
    14101 gtggcgccgc ccagccaggg gcgcgcctcc accagcgtga cgtcggcccc cgcctcctgg
    14161 agcgccaacg ccgcgctgat gcccgcgagg cccccgccga cgacgacgac gctcaccgcc
    14221 cgccccccgt caccgctcga cgcccgtcag ggcgcgggcc gccacgacgg ccttctgcca
    14281 ggtcggcagc gacacccgcg aggtcagcgc gagcgccggg ctctccgcga tgcgctccag
    14341 cagccgccgg tagatccccg ccatcgccgc cgtgcacgcc gccgagcgcc ggtcgagcag
    14401 cggcagcagc cgcagcccct cggcgtacca ggcccgcgcc cgctccgcct ggaacgcgac
    14461 gaggtcgtgc agccgcgacg ccgggtcgac gaactcgccc gtctcgtcca gctccagcgt
    14521 gcacccgaac cggtcgaggt cctcggcggg caggtacacc cggcccgcga gccggtcctc
    14581 cctgacgtcc cgcaggatgt tcgtgagctg gaacgcgacc ccgagcgagt ccgcgagccc
    14641 ctccgcgcgc tgccgcccgt cgtagccgaa cacgcccagc gacaggcggc ccaccgtgcc
    14701 cgcgacctgc tggcagtacc gcagcaggtc gtcgaacgtc tcgtaggcgg cgccgcgcac
    14761 gtcgctctcg cagccgtcga tcagctccgc gaacgcgtcc agcgggatcg ggtagcggcc
    14821 cgccgcgtcc gccagcgccg tcagcaccgg gtgcccctcc agcgcccgcg agtcggcccg
    14881 ccgccacagc acctcctgga ccgtttcgag ccgcccgcgc gcccggtcca gcaggtccat
    14941 ccggacgcac gcgggctccg ggccgtcccc gatgtcgtcc acgccccgcg cgaacgcgta
    15001 gatcgcgctc atcgcgcggc gcttcggggc gggcatcagc cggatcccgt agccgaagtt
    15061 gcgggcctcc tcccggacca cccgctcgca gtgccgatac gcctccacga cccactcggg
    15121 ccgctcgcac gtctccgaaa ccgtcatcgc tcaccctctc cgagagcgcg ggttctgcct
    15181 cgtccgtcct ggagcggatg cgtcatcgcc ggccccctcc gagagcggag gcccagttgg
    15241 cgaggagcac cggcccgcgc ggacgcggcg tccgcgccag cacgtcgtag cggccgcgca
    15301 cgagcgcggc cagcgccgcg cgccctccgg cgacatagcc cgccaccgcg atccgggccc
    15361 acccgcgcag gcccgccatg agcggcgcgg cgccccggtc gagcaggtcc cgcgcccggt
    15421 tcgactccag cgccagcacc ccgcgcagcc gcgtcggcgt caccgcccgg gacaggtcgt
    15481 cctcggcgca gccgaaccgc cgcaggtcct cgccgggcag gtagatccgc ccggccctga
    15541 agtcctcggc cacgtcctgg cagtgctcga tcacctgcag cgcggtgcag acccggtcgg
    15601 acgcctcctc cagcccccgc ccctccgcgc cgaacacgtg cagcacgatc cgcccgaccg
    15661 gattggccga caggacgcag taccccagca gttcgtcgaa ggaggcgtag cgggtcacct
    15721 cctggtcctg gcggttcgcc tggaccagcc gccggaaagg ctcctgcgga attcccctcg
    15781 cgtggacggt ctccgccagc cgccttaact gcggaagaac cggcgcccgc cctttgtaga
    15841 ggaggtccag gtccgcgtcc accgaatcga gcagcgccac ccggtgcgcg cccggcgcct
    15901 cgtcgccgat gtcgtcgacg aggcgcgcga aaccgtagac cgcgcgcagg tgggcgcggt
    15961 gccgccccgg cagcagccgg gccgcgaccg ggaagttctc ccgccgcgcg agcgcgtcca
    16021 ggccccgctc gtgctcccgc gcgctccagg gtggttcagt ggtcaccact aggagattcg
    16081 ccggtgcggc accagaaaaa ctctgatcaa ggtatggagt tattgaaccg gcgcgcgttt
    16141 ccgcgaccga aaggacgcga caggaaagtc gccttttgtg gcaattagct cgctatcggg
    16201 cgcggccggt cacggcagcc ggccgaccag gctgagcgcg acgtccagcg cgcggctgcc
    16261 gggcgtcccg tcgccctgcg ccgtccacac ctccgacagg acggccatca cgaaccccca
    16321 cgcgacgacc cgctccaccg gcatcgcgag cccgtcggcc acctgctcga tccgcgcggg
    16381 caccaggtcg accagcctgc cgtcccggtc gtcggggccc gggttgtaga acaggacgcc
    16441 cgcctcgtac ccggggtcgc ccaccacgcc gtgcgggtcg atcgccagcc acggctcgcg
    16501 ctccgcgctc aggatgttgt cgtggtgcag gtccccgtgc aggacgagcc gctcgggcgc
    16561 gctcgcgcac aactcgtcga acagccgtcc ggcgcgctcg acgaggtggc gggggagcgg
    16621 accgtcgccc gggaagcggc gcaggtggcc ggagaacgac gcgctctcct tctccaggcc
    16681 cgggagggcg catccaagag gcggcacgtg ccggagccgc cgcgccacgt cgaggaacac
    16741 ggcggtggcc tcctcgtccc tgtccgggac gagttcgctc agcaccctcc ccggctcggc
    16801 acgctccaac agcagcgcgc cccggcccgg gtcgtgctcc agcagccgca ccgcgccctc
    16861 gccgccgtag atctccaggg ccgccgcctc gatgccgagg tgtccgggtt cgggcgggcc
    16921 gagcttcagg accgccttcg tcccgtcctc cctccggacg ggcgcgaccc agtggtagct
    16981 gaggccgtac cgggcggcct cgatctccag ccgccactcg cgggcgatct cggcgagcag
    17041 gccgggcagc cgcttcagcc agcggcggcc gtcgtccccc cagacctcga cggcgttctc
    17101 gacaaggacg gacgggagcg gaccaggaag aatcggcggc atccgcccaa ccctgccaca
    17161 gggcgtgaac gcgtaggaac gccgaatcgt cctaggaatg tgacgacccc actggttccc
    17221 ggcgatcccc gcgagctcgg cgactactgg ctggcccgcc gcctcggcgc gggcgggcag
    17281 ggggtggtct acgaggcgta cggcgcggac ggcgcgcgcg tcgcggtcaa ggcgctgcac
    17341 ggggtgttcg cgggggagcg cgccggcggg ccccgggacg tgctcgcccg cgagatcgac
    17401 gccgtgaccc gggtgtcgcc gttctgcacc gcccgcgtgc tggcgttcga cctggacgcc
    17461 gagcccccgt acgtggtcag cgagtacgtc cccgggcccg acctggagcg cgccgtcgcc
    17521 tccggcggcc cgttcgggtc cggcgagctg ggacggctcg cgatcggcgt cgcgaccgcg
    17581 ctcgtcgcga tccaccgggg cggggtcgtc caccgcgacc tcaagcccgg gaacgtcctg
    17641 ctcggccccg acgggccccg cgtcatcgac ttcgggctcg cccgggccga ggacatgacc
    17701 cgcagcgcga ccggcgccaa gggcacgccc cgctacatgt ccccggaggt cttcgcgggc
    17761 gagcccgcga gcgccgcgtc ggatgtgtgg gcgtgggggg cggtggtgct gttcggcgcg
    17821 ctcgggcggc cgccgttcgc gggcgagaac ctgatgcagc tctcccacac cgtccagcac
    17881 gtggagccgg agctgcacgt gctggacgag ccgctccggt cggtggtggc ggcggcgctg
    17941 gcgaagcggc cgcgggaccg cccgtcggcg cgcgaggtgc tgctggacct cctcggcggc
    18001 tccttcgacg agggggcgat gctctcggag gggagccggg tcgccgccgc ggccgtggcg
    18061 ggtgccgcgc cgccctcgct cgcggacgtc gccgaggccg cctaccggcg gctcgacccg
    18121 ctcgcgcggg aggccgtccc cgcgatcctg ctgcgcatgg tgctgccggg cgagggcgcc
    18181 gccgacaccc tccgccgggc cgcggtcgac gagttcggcg acggtgccga gcgggcggtc
    18241 gaggagttca cgcgcgccgg gctgctggtc cgcgagggcg accgggtggc gatctgcggc
    18301 gcggcgctgc tccgcgcctg gccgcggctg cgcgggtggg tcgatgacga gcgcgccggg
    18361 ctggccgtgc accgctcgct cgcggacgca gcgcgggtct gggaccggca cggccgccgg
    18421 gccggtgacc tgctccaggg gagcgtgctg gcccgcgccg tccagtgggc cgcgaccgga
    18481 cgccgccacc tgacgctgaa cgccgtcgag cgcgcgttcc tggacgcctc ggcggccctc
    18541 ggccgccgcc gcgcccgcag ccggggcgcg ctgacggccg tcctcgccgt cctgctggtc
    18601 gtggccgtgg gcggggccgt cgtcgcggtg aaccagcgcg cggtcctctc ccgccagcgc
    18661 gaccgggcca tcgccgaccg gctcgccgcg ctcgccgcgt ccctccagcg cgacgacccg
    18721 cgcaccagcc gccgcctcgc cctggccgcc gcgcgcgtcg gcgacgacga ccagacccgg
    18781 aaagccctca tcaacgccat gtaccagtgg gagggcgata cgttcaaccc cgcctccaat
    18841 gcccaggtgg tactcacccc cgacggccgc accgccacgt tcgacgatcg cgtccaggtg
    18901 acacgctggg atctgaagac gcaccagcgc gttccgatgc cgccgggggc cgagccgaaa
    18961 agcgcggccg tgttcagccc ggacggacgc cacatggcgc agctcttatc caccggagga
    19021 gatctgagcc ggcgcggtgt ggtccaggtc tacgacgcgg ccaccggaaa gccgcagggc
    19081 aggccgatgg gcgatccgcg tcaatccttc tggaacctgc ggtacagcgt gagcggcaac
    19141 ctgttgatga tggacaacgg gcctggaggc tccggcgatc cccgaacaac cgctcccgaa
    19201 atggctttat ggaacgcgcg cagcggtcgc ctcgccatga gctggaagga gcgcccctac
    19261 gcctgggccg tgagcgccga cgacgccctg gtcgcgatgg tcctgccgag cggcttccaa
    19321 ctgtgggacg tcgcggcccg caaacggatt cccacgccgt ggctgggcgc ggcgctggct
    19381 tccgagagcg cgtcccagcg gatacgccag gtcgggttcg ggcccgccgg agccaggctc
    19441 gctttggtcg tcggcagcag ggtgaccgtg cttgatctga acaacctggc gcgcaccgag
    19501 cccgtcgcct cgcggtcccg tgtcccctgg cacgagcgga gtgcgcgcgg cgtggacgaa
    19561 ccggtgttca gccccgacgg ccgcctcctg gccgtcgggt tcactctatg gaatctggac
    19621 ggctccgccg aggcgcccct gatggcccgc gggctcgacg acgagacgcc gaccgactgc
    19681 cgcttctccg ccgccggtga cctgctgcgc tgcgcgacga ccctcaaccg cgtcgtcacc
    19741 acgaacatct cgggctacgc cgaccggatc tccgtcggac gcgacgccgg acacggggtg
    19801 ctcagcccgt ccggcgacct cctcgcctcc atgggcgcgg acagcgtctc catcaccggt
    19861 aatccggcgg ggtggacgtc ccccatctcc gtgccttcct tgagaagcgt ttggcgaggg
    19921 atggtcttca gccccgacgg cggtctggtg gccattcccg accggaaccc ggacgacggc
    19981 ttcggcgtgt gggacgcgcg cacactccag aaggtcgcgg agctcgactg gcccgacggc
    20041 gcgctcggca aaggcgtcgc gttctccccg gacggccggt ccctcgtcgg cggcctgaac
    20101 gcggaggtca tcgacccgcg gcacccctac aagtcgtggt tgcaggagtg ggacgcccgc
    20161 tcgggccggc gcacccgcgt catcccgttg gagtcctccg gatcggggga gctgttctac
    20221 cgatccgacg gtcgtacggt gaccttgaag agcgccgtcg tcgacatgga ttcaggacaa
    20281 gtccacaagc ggttcgactt cttcagcgtc gtcgacgtgc tggccgtgtc tcccgacggt
    20341 tccgtcgccc tggtcatcat caaccccgac gacttgtacc tgtgggacct ccgaggcgac
    20401 aagcgaagag gaacgcccct ggccgccgtg cccgacgtgg aagacctgcc cgccgcgttc
    20461 tcccccgacg gccgcctggt cgccaccagc gacgcgcgcg gcggcgtcca cctgtacgag
    20521 gtggccaccg gacggcccta cggccccacc ctccccggcc acgccggtgg agtcgacacc
    20581 ttcgcgttct cccgagacgg caccgtgctc tacacctacg gaggcgaccg cacgattcag
    20641 gccaccaccc ttgatcccgc ccgcctcacc gaccggctat gcgcccaggt cggcggcctg
    20701 agcgaagccg agtggaacca gtacgtcccc gacctctcct atagacccgt ttgtggctaa
    20761 agatctttac atgtaggcca tcacgtcggg cccggatggc tccagccgtt tcggcgaaat
    20821 gcaccacggc ggccttggct gaaccttgcg ggtcggcgcc ctggcgtcca aatcgatctt
    20881 gcggagaaaa ctttgaaagt atggccggga atggtgtttt cgggtcgtcc ggcttgtccc
    20941 cgcatgggga gatcggtgat cttggagcga ccgggacggg tcggtcaatt cgccacaatc
    21001 ggaccgttcg gcgcaccgat cgaccgttcg gccgacaggc cctgaccgcc ctcctgacaa
    21061 gccgttgtga tcatgcgatg ctccgcccga cgacgtcgaa cagtcgacgg gcggcccggc
    21121 cgccccggcc aggaaggggt cacggcgatg cgcgcgagac gacggacgac ctgggcgaac
    21181 agaagaagtc gcagctggcg gctgtccctt gtggcggcgg ccgtggtgct gctggccggc
    21241 gtcgccgcgc ccggtgcgcc ggccgacgcg gccccgaagg cggaggtgtg cgaattcagc
    21301 gtccagaagg acgtccctgc cactatgcgg gacgggacgg tgttgcgcag caacgtgttc
    21361 acgccgaaag gggacggcaa gttccccgtc atcctgatgc ggctgcccta caacaaggag
    21421 ggcgccctga gcttcgtcta cggcgccccg gaccgttacg ccaaggcctg ctacctcgtc
    21481 gtggtgcagg acgtccgcgg cgagtacaag tcggacggcg ccttctaccc gtaccggacc
    21541 gaggctgagg acggctacga caccatcgag tggtccgccg ccctgccgca ctccaacggc
    21601 aaggtcggca tgtacgggtt ctcctatccg gggctcacgc agtggctgcc cgccaccctc
    21661 acgcctccgc acctggtcac gatcgccccg gcgttcacgt cctccgacat ctacgacgga
    21721 tggacctacg agggcggcgc gctgtaccag gcgttcatcc aggactggct gctgagcttc
    21781 ctcaacgggg gcgtcatcag caagctcccg gacgccgcga agctgcgggc ggagatgacc
    21841 caggcgtcgc gggacctgca caccaagtgg taccggcacc agccgctgaa caacttcccg
    21901 ccgctgtacc cgggggacaa ccgcatcgcg ccgtactact tcgactggat cgaccacccg
    21961 agcgacgacg actactggaa gcgctggagc atccgcacga agtatccgcg ggtcaacgtg
    22021 ccgtcgctga acttcggcgg ctggtccgac atcttcctca acgggacggt ggagaacttc
    22081 gccgggatgc gcgcccaggg cgggtccgag gtcgcccggc aggggtcgca gctcctcgtc
    22141 gggccgtgga cgcacggcgg ctcgggccgc acggtgggcg ccgtcgactt cggtccggag
    22201 gcggtcgtcg cggtgggcga tctgcacctc cgctggttcg accactggct gaaggggatc
    22261 gccaacggcg tggacgcgga tccgccggtg aaggtcttcg tgatgggcgc caacaagtgg
    22321 cgcacggctg actcctggcc gatccccggc accgccaaca ccacgtacta cctgcacagc
    22381 aagggcgacg cgaacaccgc gaacggcggc ggcacgctcg acagcaccgc gcccgcgacg
    22441 ggcgagaagg ccgaccagta ccagtacgac ccggcgaacc cggtgccgag cgtcggcggc
    22501 cgtttccaga gctcggtacc cggcggcccg caggaccagc ggtccgtcga gcagcggcgg
    22561 gacgtgctgg tctacagcac cccgcggctc accaaggaca ccgaggtcac cggcccgatc
    22621 tcggtcacgc tgtacgccag gtcctcggcg aaggacaccg actggacggc gaagctcacc
    22681 gacgtccagc cggacggcac ctcgatgctg gtccgggacg gcatccagcg cgcccggtac
    22741 cgggtctcgc tggagaagcc ggagctgatc acccccgggg aggtctacaa gtacacgatc
    22801 aagctgtggc cgaccagcaa cgtgttcaag gcgggccacc gcatccggtt ggagatctcc
    22861 agcagcaact tcccgatgta cgaccggaac ccgaacacgg gcgggaagtt cggtgccgac
    22921 acgaccacgc agcccgcgtc gcagaccgtc ctgcacgacc cggagcaccc gtcgtcgatc
    22981 acgctgccga tcattccggt gcccgtccgc tgacccggcg caacggctgg cccgcgcccc
    23041 cgccgcgggc ctgccgctgc ggtcgaaccg cggccggtac ctccgctcgg cgagccgcag
    23101 ccgcccagcc ggggcggcgt cagattcggc cggtctcgtg ggcccacatg gcgacctcga
    23161 cgcggttccg ggcgccgagc tttcgcatga ggctggcgac gtgggccttg acggtgctcg
    23221 gggtgatatg cagctcgccg gcgatctcat tgttggtgcg gccttgggct acaggcacga
    23281 ggacttcctc ctcgcgggcg gtgagcggtt ctatcggctg cctccgtggt ggggtctgtg
    23341 cgtgggcgaa ggccgcgagc agccggacgg tcacgctggg cgcgatcagg gcgtccccgt
    23401 cggcggcggc gtggatggcc tgggtcagca gggcgggtcc ggcgtccttg agcaggaacc
    23461 cgcgggcgcc ggccttgagc gccccgtaga cgtactcgtc gaggtcgaag gtggtgatga
    23521 ccacgatcgg cagtggatcg gtgacgtcgg ggccggcgag gcgccgggtg gcctcgatgc
    23581 cgtccatcag cggcatccgg atgtcgaaca ggccgacgtc ggggcgcagc cggagcgcca
    23641 ggcggaccgc ctcgcgcccg tcggcggccg cgccgaccac ctcgatgccg ggttgggcgt
    23701 cgagcagcat ggtcagcccg gtgcgcacga tgggctggtc gtcggcgacg aggaccctga
    23761 cgctcatcat ggcgtcccgg ttcggggcag gaccgcctcc acccgccagc cccgctcggc
    23821 ggcggggccc gcgtggaagg tgccgccgag cagcgaggcg cgctcccgca tgcccaccag
    23881 gccgtagccc gccggggcgc ggccgccggc ggcggagccg tcgtcgtcga cggtcagccg
    23941 cacctggtcg gcgtcgcctg tgacggcgac ggtgaccttc gacgcgtgcc gggcgtgccg
    24001 tcgggcgttg gtgacggact cctgggccag gcggtagatc gcggtcccga ccgccgggct
    24061 gaggtcgtcg aactcgccgg acagcgtcac cttgacgcag gggcgcgtcc ggccatcggt
    24121 ggcgagctgc tcgacctcgg ccacaccggg ctgcggcgcg aacccggtgt cctgcgtggc
    24181 gcggagcacg ccgacgatgg cgcgcagctc ggtgagggtg cggctcgccg cgtcctcgat
    24241 gacggccagg gcctcgacgg cacgctcggg gtgggaggcc gcgacggcac gtcctgcctg
    24301 ggcctggatg gcgatgcccg tgacgcggtg ggcgacggtg tcgtggaggt cacgggcgag
    24361 ctgttcgcgt tcgcgggcct tggcgtggtc gatgtcgcgg atgcggatct tcgtgcgata
    24421 gcggatcgcg gtgccgagcg cggcggcgaa caggaagaac gcgtatcccg cgaccacctc
    24481 cgccagggtg gtggggtcgg cgccgagggc ggtgatgagg gccggccaga gcaggatgac
    24541 gccgaggccg ctcgcggctt cccggccgga gccccaccgg aacaaggcgt aggccaggat
    24601 cagcaccgcg atgccgctgt tcagcagggc gccttgcgtc ccggtgagga ctctgacgac
    24661 gtcgatgatc gtcaacgtgc cgaaggagac cacgaccgcg acgagcgggt gcgtgcgtcg
    24721 ccacagcagt gggccgagga ccgcgagcac cgccagcagc agcagcgggc gtggcgccag
    24781 gtcctggcga agcaccgctt ccgccgcgga ccagcagatc agtaccgcga ccaaggccca
    24841 gtcccgcggc cccagggccg gggcattcgc gggtcgaggt tcggcccaca gcgagcggag
    24901 tgcgttggtg gccatctgat gagcctaggc agcccgcggg ctcgatgtat ccgccgaaag
    24961 tacaagagcc cggctgtgcc aaaggccagg tcaaaccagg ttccgcggcc gatgtgcccg
    25021 ccgccggcat ccgtgagggt ggaagcaccc acccgatcac agggagtccg tgatgagaac
    25081 gccccaatcc caaaccgcac cagagaatcc gtcgtcccag agcacgctgg aggacctgcg
    25141 cctacccgtg caggccaagc tcgcagcggc atggaccagc ttcatgttcc tctacatcta
    25201 cgtcgactac ctcgccctgt acaagcccgg cttcctcgac gacctcctgg gcggcaccgt
    25261 ccacgagttc gacaccggcc cgaccttcgt cgccgtcgcg ctctcgctca tggccgtccc
    25321 gatcctcatg atcctgctct ccgcgacact gcccgcccgc gtcaaccgca ccatcaacgt
    25381 cgtcgtcgca gcgctctaca tccccgtctc ggtgttcaac gcggcagggg agccgtggtc
    25441 ctactcctac ttctacggcc tctccatcgg acttgagttg ctgctcctgg ccttcatcct
    25501 gcgctccgcc tggtcctggc cacgccgcat cacatcaccg gcgaccctgg ccaccaccct
    25561 cgacagcgag ccgcagcagg cgtgaccacc ccccgcgcct gaccatccct cgcccgcgcc
    25621 gcccgcgagc acggatggtc atgccggcgt ggcaatgccc cagggctcgc ccagagcggc
    25681 agaacaccgg cccctctccc cttcgcgtac ctccaacttt tcgccctgag cacccggaac
    25741 cgcggcacgg tcatcgcgtc ctcgccgcct ctgcgagagt ttggtcgcga tcgacgtgga
    25801 cgagacgccg ctacctagtc gaggacgccg cgtccggggc ttgaatgggg gactgcgggg
    25861 ttaaccggtc gcctgaacga agacgccgac cgaggcaccg gaacatgatc gccccagcgg
    25921 cacccacccc ctgcggtccc taggccgaag ccaccgcatg aacgcagcag gtgaggggct
    25981 tcgacctgcg aggagaccaa gccatgccat cgacggcatc tgcggggaat tatcctggcg
    26041 ggatagacgc cctccctctg gtcgcg
//
