LOCUS       NZ_JAHFZY010000003     22565 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Actinomadura sp. NEAU-AAG7 Scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZY010000003
VERSION     NZ_JAHFZY010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura sp. NEAU-AAG7
  ORGANISM  Actinomadura sp. NEAU-AAG7
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 977316)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Actinomadura oryzae sp. nov., a novel actinobacterium with the
            activity of releasig potassium isolated from rhizosphere soil of
            rice in Sanya
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 977316)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, 600 Changjiang Road, Xiangfang District,
            Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603865.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:10:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,952
            CDSs (total)                      :: 7,871
            Genes (coding)                    :: 7,813
            CDSs (with protein)               :: 7,813
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 6 of 58
            Pseudo Genes (incomplete)         :: 53 of 58
            Pseudo Genes (internal stop)      :: 1 of 58
            Pseudo Genes (multiple problems)  :: 2 of 58
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:01:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 622437
            Orig. end                         :: 645002
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZY010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22565
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22565
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22565
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12565](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12565)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(1170..2063)
                     /locus_tag="KLI87_RS17485"
                     /old_locus_tag="KLI87_17490"
     CDS             complement(1170..2063)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889676.1"
                     /locus_tag="KLI87_RS17485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17490"
                     /product="inositol monophosphatase"
                     /protein_id="WP_156218400.1"
                     /transl_table=11
                     /translation="MRSTTASPALPVDLGEARRVAVDAAEAAGALLRAGTGGPLVARPK
                     GGNGDVVTELDTAAEELILGRLRAAYPGHRIIAEESGVLDGADGSHLVWLVDPLDGTNN
                     VAIGMPVYAVGLALCAGSVPVLGVVHDPVSGRTWTAVRGEGALDPDGAPLTLAPRPRPG
                     RERNPVLGWTQGHAVKAGDPSALALRTALELRCSRLLQLWAPLVAWAMLARGDIDGIVG
                     YRPELVDLPPGALLAAEAGAELRRLDGGPYELSIDRTPSELGFVAARPELLARLVETAN
                     RALDTAGPDGQIPLVR"
     gene            complement(2111..2827)
                     /locus_tag="KLI87_RS17490"
                     /old_locus_tag="KLI87_17495"
     CDS             complement(2111..2827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889677.1"
                     /locus_tag="KLI87_RS17490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17495"
                     /product="hypothetical protein"
                     /protein_id="WP_214617874.1"
                     /transl_table=11
                     /translation="MRYEEIRREIEAGTAARTLPAWAGRVLADVAEGRSRVPAVRHPLG
                     FLCLPVERAGDFGVCLHIWTSEVDPAPSTTSPVHCHSWDLLSFVLYGTVRNVRMDVGEG
                     PGGAAAQVFEVVSRGEVDELRATGRTVRYSPGRSTAHGTGESYTLPAGVFHSTLIEDGR
                     DAATVALGRQTPGGGDLSLGPPDVATHRVRRARSDPGEAARALHRSAREVANAYAARPA
                     PPGPGRPRDDLSPTRR"
     gene            complement(2892..3905)
                     /locus_tag="KLI87_RS17495"
                     /old_locus_tag="KLI87_17500"
     CDS             complement(2892..3905)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543765.1"
                     /locus_tag="KLI87_RS17495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17500"
                     /product="hypothetical protein"
                     /protein_id="WP_156218399.1"
                     /transl_table=11
                     /translation="MTRFATWLGKNADAFIALILAITVAVLGVGVDLPHEDEVTNSAIL
                     AVVGLLATSVLRDRGRRVPVEAEVRDTLRASSATLDELSGKLTHIETFEGVLADTKRAL
                     DETTIVRVISGAQVAQVLEEARRDTDRWIFKGGTGTYIRAKTLPETVAAARRDGRTLLF
                     RLEIIDPTDVEVCEAYARHRRSSADGPDGTGEPWTLERTRKEAYATILAACWHKQRFGM
                     LDIDIGLARTMTTLRYDLSSSLIVVTRDNPRGQALVVDSTKFYYSWLSAELLTSLDQAR
                     RVPVEQARLAPLDDEPTVEEVRRLFEVIGIDMAQGYTDRDVIEIIRKALRPKDPYE"
     misc_feature    complement(3907..3918)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.15"
                     /tool="antismash"
     gene            4093..5247
                     /locus_tag="KLI87_RS17500"
                     /old_locus_tag="KLI87_17505"
     CDS             4093..5247
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657178.1"
                     /locus_tag="KLI87_RS17500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17505"
                     /product="sensor histidine kinase"
                     /protein_id="WP_214617875.1"
                     /transl_table=11
                     /translation="MQLRGWWSAAWPTPRSRALDLTLAVSLAVVDGVFLWFAPQDFWLP
                     PAVTSVGSFLLGLGLVFRRRHPVRLALVAVALGTVAGAGVFALVVILYSLAAYTPNRRT
                     VWTIAAVGYVSGIAFPGPTESDDPFLAQAIFGVAFTAVPILLGLYMGARKQLLASLQER
                     ASRLEREQHLLAERARGEERTRIAREMHDVVANRISVMVVHAGALKAIAVRDPGRAAET
                     ATVIGDMGRQALEELRHVIGVLRQGEEALPQEAVTLAHVRELVDQSGAAGLVVDLAVRG
                     EERPMPPAVGRTVYRLVQEALTNVHKHAGAADTRVGLGLLPEAVEVEIANDAPTAPPDH
                     GLPSGGHGLVGLRERVTALGGSFEAGPSADGGYAVRARLPLPAS"
     gene            5336..7453
                     /gene="uvrB"
                     /locus_tag="KLI87_RS17505"
                     /old_locus_tag="KLI87_17510"
     CDS             5336..7453
                     /EC_number="3.1.25.-"
                     /GO_component="GO:0009380 - excinuclease repair complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrB"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657177.1"
                     /locus_tag="KLI87_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17510"
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="WP_156218397.1"
                     /transl_table=11
                     /translation="MRPVTDLRRRVAPFEVVTEMTPSGDQPQAISELAERIGRGDKDAV
                     LLGATGTGKTATIAWLVEKLQRPVLVMQPNKTLAAQFANELREMMPGNAVEYFVSYYDY
                     YQPEAYIPQTDTYIEKDSSINDEVDRLRHSATNSLLTRRDTVVVASVSCIYGLGTPQEY
                     VDRMVRLQTGQRIERDDLLRQLVGMQYTRNDLAFTRGTFRVRGDTVEIIPQYEELAVRI
                     EMFGDEIEKLATLHPLTGEVITEDDELYVFPASHYVAGPERMERAIAGIEAELEETLAV
                     MERQGKLLEAQRLRMRTTYDVEMMRQVGTCSGIENYSRHIDGRGAGTAPNTLLDYFPED
                     FLLVIDESHQTVPQIGAMYEGDASRKRMLVEHGFRLPSAIDNRPLKWEEFLERIGQTVY
                     LSATPGNYEMTRVGGDVVEQVIRPTGLIDPEIVVKPTKGQIDDLIHEIRLRTDKDERVL
                     VTTLTKKMSEDLTDYLLELGIQVRYLHSEVDTLRRIELLRELRAGEFDVLVGINLLREG
                     LDLPEVSLVAILDADKEGFLRSETSLIQTIGRAARNVSGQVHMYADTVTPSMERAIDET
                     NRRRAKQQAYNTEHGIEPQALRKRIADILDSLAREDADTETLIGGAGRQQSRGKAPVPG
                     LASRTREVGRHAADLVGERPREELEGLIEQMTAQMHQAATDLQFELAARLRDEIKELKR
                     ELREMKEAGVS"
     gene            complement(8101..10011)
                     /locus_tag="KLI87_RS17510"
                     /old_locus_tag="KLI87_17515"
     CDS             complement(8101..10011)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="KLI87_RS17510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17515"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_214617876.1"
                     /transl_table=11
                     /translation="MDAEAPAPGGRAGHRRSTAGPREVLRLAAGHRGAIAATVAATLLA
                     SALALAQPLVARDVIAAAGSGRTPWAAVGALVALFAGQALVQALVRFQLARTGEGIVLG
                     VRLNLIDHLLRLRMPVYDRHRIGDLISRADADTLALRQIIAGGLTDAVTGAIGLAATVV
                     LMLWLDWALFACVAAVVAGAGTALALALRGMRAASLRGREAAGEMAAGLERALSAIRTV
                     KAGRAEPRESARIGGRAEAAYAANVRMAGFDALVSPATQLAVTGSFLVVLLVGGTRVAG
                     GTGSVADLVAFLLYMLYLTAPLGSIFEAFSAVQQGTGAVHRITEALALPRETDAAPGLP
                     ALPRPPGATSGLAGDEVSAGPCAQGGTVAEPGANGGRAAALEFREVWFGYRRGRPVLRG
                     VSFQVPAGGHVALIGRSGAGKSTVFALAERFYDPDRGEVLVEGVRADSLSRDGHRSRIG
                     LVEQDCPVLDGTLRENLVYAVPEAGEEEIRRAVAMTNLDELVSRLPEGLDTRVGEHGRE
                     LSGGERQRLAIARALVARPRLLLLDEPTSHLDLESEVALHRAIEEAAGRCALLVIAHRF
                     TTVRAAAGVIVLDQGRIAASGTHEQLLETSAYYRDLASQWLARRGDRSTTGSGREHAGR
                     G"
     gene            complement(10001..10441)
                     /locus_tag="KLI87_RS17515"
                     /old_locus_tag="KLI87_17520"
     CDS             complement(10001..10441)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559151.1"
                     /locus_tag="KLI87_RS17515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17520"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_214617877.1"
                     /sec_met_domain="PF13471 (E-value: 1.9e-23, bitscore: 78.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPSALERPPKGPLRRRAAARLAVLLARLVALLPPARIRTLLTL
                     LSRGASPATYDQAKRARDAVLAGSLACLGPRGCLPRSLATVLLCRMWGAWPSWCVGARV
                     RPPFGAHAWVEAEGRLVEENVPDGYLAALITVPPRRDGARGR"
     gene            complement(10438..10695)
                     /locus_tag="KLI87_RS17520"
                     /old_locus_tag="KLI87_17525"
     CDS             complement(10438..10695)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="KLI87_RS17520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17525"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_156218396.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.3e-07,
                     bitscore: 26.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.7e-26,
                     bitscore: 87.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-19, bitscore: 64.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLRLRPGVSTTDTAYGTVLLDERSGDYWQLNPTAALALRLLADG
                     RTAEQAAAAMAEEFDVDEPRALRDVTALVGQLRAAGLVRP"
     aSDomain        complement(10444..10689)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KLI87_RS17520_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="5.40E-28"
                     /identifier="RREFam002.1"
                     /label="KLI87_RS17520"
                     /locus_tag="KLI87_RS17520"
                     /protein_end="84"
                     /protein_start="2"
                     /score="87.8"
                     /tool="antismash"
                     /translation="LRLRPGVSTTDTAYGTVLLDERSGDYWQLNPTAALALRLLADGRT
                     AEQAAAAMAEEFDVDEPRALRDVTALVGQLRAAGLVR"
     aSDomain        complement(10543..10695)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KLI87_RS17520_Lasso_Fused_RRE.1"
                     /evalue="7.60E-09"
                     /identifier="RREFam003.1"
                     /label="KLI87_RS17520"
                     /locus_tag="KLI87_RS17520"
                     /protein_end="51"
                     /protein_start="0"
                     /score="26.5"
                     /tool="antismash"
                     /translation="MGLRLRPGVSTTDTAYGTVLLDERSGDYWQLNPTAALALRLLADG
                     RTAEQA"
     misc_feature    10685..10698
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.43"
                     /tool="antismash"
     gene            complement(10733..12565)
                     /locus_tag="KLI87_RS17525"
                     /old_locus_tag="KLI87_17530"
     CDS             complement(10733..12565)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="KLI87_RS17525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17530"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_214617878.1"
                     /sec_met_domain="Asn_synthase (E-value: 5.9e-45, bitscore:
                     150.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHDGMPGHGEASFVVLPDHEAALAVAAGLPTPPERILRHRSGR
                     PWLAGRWSDAEMTEAAAGDARIAIIGTCPIGPERLAREAGRLRDLASLDRLVRSLPGSF
                     HLVAALDGRTRVQGDAAGLRLVFHTRAGGVTVAADRADTLAALTGAALDERQVAARLLW
                     PLPHPLLHTPLWRGVEGVEPGAHLLLEPDGRARTRRWWAAPEAVRPLATAADEVAAALT
                     AAVDARTAGGGVVSCDLSGGLDSTSICFLAARGEAEVVAATWPGRDPADEDLAWARRAA
                     AHLPGVEHAVWPAEDASLVYAGLLEIDDPLDEPSIGVMDRARMLDHVPRLAARGSRLHL
                     TGIGGDHVAWCSEAHYHGLLRRRPLLALRRLRGFRALFDWPLAPAARALADGRPYRRWL
                     LDAAGDLRAPARPAVAGALGWDTAPRLFDWVTPEAAEAAAQVLREAARTAEPLAPDRGQ
                     HLDLHSIRACTRIIRQWERMSARAGLPMASPFLDDRVIEACLAVRAEDRVTPWRYKPLL
                     VAAMRGVVPAECLARANKAEASMDAADGLRAHSRDLMELCEDSRLARLGLVDGERLKAL
                     LARPDTPALRGAILYSTLGCEVWLRTLDRRRARR"
     gene            complement(12584..12691)
                     /locus_tag="KLI87_RS17530"
                     /old_locus_tag="KLI87_17535"
     CDS             complement(12584..12691)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.4"
                     /locus_tag="KLI87_RS17530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17535"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_156218394.1"
                     /transl_table=11
                     /translation="MQKYETPALVAAGSFRKVTGLLGFHGNDRVILSKN"
     misc_feature    complement(12968..12985)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            complement(13196..14095)
                     /locus_tag="KLI87_RS17535"
                     /old_locus_tag="KLI87_17540"
     CDS             complement(13196..14095)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891210.1"
                     /locus_tag="KLI87_RS17535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17540"
                     /product="phosphotransferase"
                     /protein_id="WP_214617879.1"
                     /sec_met_domain="APH (E-value: 5.6e-23, bitscore: 77.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYAETPLTGAMRKAVQDAWNVPADGPAERLFGGEESAAYRIGAL
                     VVRVGPAWRSDAETEWCHAVAAHAASRMPEAVAPLRARDGATVVRGDGRPLSLWRHVEG
                     EWPDTEEPTTRTQAAALLARLHRALADHAPPPRPTRSFAEIGLDGAFPEDVPELADPDL
                     DRWLAAFHARTPARQVVHGDYYEGNTLARGGRLVALLDWDEAFVAAPEFEVASAALEWT
                     DEHARAPELRRRFVADYHAAGGTAGPMDEETVAQLIRHRLRRETAYFNLARARGVEHDE
                     DDLDYHRRRVREFFALKP"
     gene            14190..16352
                     /locus_tag="KLI87_RS17540"
                     /old_locus_tag="KLI87_17545"
     CDS             14190..16352
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.5"
                     /locus_tag="KLI87_RS17540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17545"
                     /product="MMPL family transporter"
                     /protein_id="WP_214617880.1"
                     /transl_table=11
                     /translation="MMNLPVRAARWSAGHPWRAIAGWFLFVALCLGVGISVGGHAATSA
                     DFRVGEAGRAEAMAAEGGLQNKPVERVMISGEGARDAAARDIAGRMKGLPEVESVAAPV
                     RAPGGDVVRVDVTLKGAELDGRKHVEPLREQTDAVRAAYPGLRVEETGGPSVSKGVEEL
                     RGKDLSRTEVIALPVTLITLLLVFGSVALAVVPLLLALSSIVAAVGLSMLASHVFPDAG
                     VGTNVILLIGLAVGVDYTLFYLKREREERARAGGRLSPRAVVELAAATSGHAVVVSGLA
                     VAVSSATLFLADDVIFSSLATGAIVVTLVAVASSMTVLPALLAKLGARAERRRERRARR
                     GKAVRAHREDGAGRITTALLRPTEKRPAVTLAVAVLAMLALASPLLGLKLTDMGRETHP
                     RSIPAVQSYHRMNAVFPELKSTHQVVVRADAGRSDEVRAALGDLAGRTRGDRRFAGAPS
                     LRTSADGRVSLLELPVPHYGSEDAARASLRDLRKRYIPASLGKLDADVAVSGDVARYTD
                     YPEHQKDKLPMIIGALLLVTFAMTAWAFRSVVLGLVGVVLNLLSAAASLGVLVAVFQYT
                     WAEGLLGFTSTGSIGSRVPLLLFVILFGLSMDYQVFVISRIREAALAGVPTRRAVLEGV
                     GGSARVVTSAAFVMVTVFASFVPLHIIEMKQMGFSLAVAVLLDAAIIRIMILPAAMLLL
                     GERSWWPSRGMRRVRAAAERPAEKVG"
     gene            16358..17566
                     /locus_tag="KLI87_RS17545"
                     /old_locus_tag="KLI87_17550"
     CDS             16358..17566
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="KLI87_RS17545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17550"
                     /product="sensor histidine kinase"
                     /protein_id="WP_214617881.1"
                     /transl_table=11
                     /translation="MDARPQLDDRFQVRALVRWYAALWLVLGLIPQVLAAADDPGAARV
                     SGIVLPVVLGACYAVTELYPRVLPPMAYLCVLAAGVGALSYVRGGGASLYIASLPQFWI
                     LTRSQRYAVALSGAAGLATLAGEVAAGAAHLPTGNMLFTVGGFLAGLLLGLAAHRYVRQ
                     TEERARRLSAELAVAQRELAEANRRQGAAEERERLAREIHDTLAQGFASIIVLAEAARA
                     GLGAEPGRSEQQLRSIERTARDNFAEARALVDSARRDGPAQGPVAATLRRVLDRFTEDT
                     GIPVGAELPDVECDQPARIALLRCTQESLANIRKHAGASSVGVVLERHPHGVELEITDD
                     GRGFVVGAAAGFGLEGMRRRLAELGGELTVTSSVGDGTRIHVMIPLSPQDPPTPLISTS
                     PQE"
     misc_feature    16378..16392
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.1"
                     /tool="antismash"
     gene            17568..18209
                     /locus_tag="KLI87_RS17550"
                     /old_locus_tag="KLI87_17555"
     CDS             17568..18209
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544254.1"
                     /locus_tag="KLI87_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17555"
                     /product="response regulator transcription factor"
                     /protein_id="WP_214617882.1"
                     /transl_table=11
                     /translation="MTDRTLRVIVVDDHTVMRAGVVALLATEPGIEIVGEAGDGRAAVD
                     LAARLRPDVALVDLRMPVLDGASATAEIVAGASGTRVLILTTYDTDAEIERAIEAGAVG
                     YLLKDTTRERLADAIRSAARGETVLAPRVAERLVARMRRPAQVPLTAREVDVLNGVADG
                     LSNADIGRRLVIAEATVKTHLLRVFAKLDVSDRTHAVVVAMERGLLPRPR"
     misc_feature    complement(17602..17617)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.25"
                     /tool="antismash"
     misc_feature    18263..18272
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            18297..18794
                     /locus_tag="KLI87_RS17555"
                     /old_locus_tag="KLI87_17560"
     CDS             18297..18794
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630640.1"
                     /locus_tag="KLI87_RS17555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17560"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_156218389.1"
                     /transl_table=11
                     /translation="MEYEVRLARPADLAVLPAIENSADPLFAPLGIVFPPGPTVIEQMD
                     GADVEILVAGDPPVAFAAVEEVDGATHLEQISVRGDLVGRGIGTRLLATVRERAAAAGS
                     PGVSLLTFRDVPWNGPWYAAHGFAELPEERWGPGLRAYWKAEIEAGLHDLGPRTVMWAP
                     SR"
     gene            18940..19986
                     /locus_tag="KLI87_RS17560"
                     /old_locus_tag="KLI87_17565"
     CDS             18940..19986
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630638.1"
                     /locus_tag="KLI87_RS17560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17565"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_156218388.1"
                     /transl_table=11
                     /translation="MTGPGSWARWARGRFGERGLALTALVALLALAVVPLVALPAVRCE
                     VFGSGCRTPPPEVRADPVSAPGRQFTPVEAATRGGYVALGDSYSSGVGAEATVGDNNPL
                     ERCHRTSKAYYNEVSKAFPFAKGTSFWACSGATTADIRDGRHGEPSQLGRLNADTSLVT
                     LSVGGNDIGFSKVVAGCVVKLPWSRSCFRQGDDIARKMSDLRRNLPELIGQIHARAPHA
                     RIILMGYPKAFSEVEGTGGDNLRVSEQQWLNARAYDLGRLIRETAAEADRRIAARHQQG
                     SVEFVDSYSAFAGHEVGSGQPYMNGLTVNLSALEAEPRSYHPTVSGQHALAGLFIEQVK
                     KGPGRPVS"
     gene            complement(19983..20567)
                     /locus_tag="KLI87_RS17565"
                     /old_locus_tag="KLI87_17570"
     CDS             complement(19983..20567)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617723.1"
                     /locus_tag="KLI87_RS17565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17570"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_214617883.1"
                     /transl_table=11
                     /translation="MRKNVERRAALVDAAIEVLARDGARGLTFRAVDAEAGVPVGTASN
                     YFAKRDDLFTQAGGRIYERLQPDAATLGGMLEGPRDLARVTALLTETVDRISAFRTGYL
                     ALLELRLEATRRPGLRAVLTERVREDVEANVARHLESGMPGDATTVRLLYLTLNWLIVE
                     NLTLPEVFTEEDVRRLVADAVERSLPRQDPR"
     gene            20637..21269
                     /locus_tag="KLI87_RS17570"
                     /old_locus_tag="KLI87_17575"
     CDS             20637..21269
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545255.1"
                     /locus_tag="KLI87_RS17570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_17575"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_214617884.1"
                     /transl_table=11
                     /translation="MRKLVYYVGTSLDGFIAGPGGEIDFLPVSDQVMAWIGERYPETLP
                     THVRPHLGIQDAPNQRFDTLVMGLGTYRPALDIGVTSPYAHVRQYVASTTLPEIADPAV
                     TLVRDPLELVRSLKAEDGGMDVWLAGGGRLAAALLPEIDEMVVKSYPVVAGAGVPAFAG
                     GFRPTRFTPTAREEFDNGTQVTWLTRTPQPALGSRPLAHRALGPYGG"
     gene            21325..21810
                     /locus_tag="KLI87_RS17575"
                     /old_locus_tag="KLI87_17580"
     CDS             21325..21810
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLI87_RS17575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLI87_17580"
                     /product="hypothetical protein"
                     /protein_id="WP_214617885.1"
                     /transl_table=11
                     /translation="MIWVRPALGLLSAAVLVPAVAIVGYGAVEGVSVPLSMSTVSATSA
                     QRNGRGAARGTRGLRYVKTLRGQGVSHGTVTVGARGVVVRGTHRDLRCEDGPSYLKITV
                     VLAGLPDAEHAAGLACGQTREVAFAYAWTGASSAVHLQVCGRRRDACGGRSTVLRPG"
     misc_feature    complement(22123..22137)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 accgcgtcag ggtggggctg ctggccctcg ggctggtctt cgtcgcgacg ggcctgctcc
       61 cgcccgcgac ggcccgcgac agcgtcgagc gcatcgcgcc gctgctgctg ttcctgctca
      121 gcgtcatcgt gctggcggag ctgaccaagg aggccggggt cttcgacgcg atcgcccagc
      181 ggatggcgag cgcgggccgg ggcaactacg ccgcgctgtt cctgctgtgc gtggggttcg
      241 cggcggtcac caccgtcttc ctgaacctgg acacgaccgc cgtgctgctg acgccggtca
      301 tgctggcgct cgcggcgcgc gcgcggatcg ccgcgctgcc gctcgccatg acgaccgtgt
      361 ggctggccaa caccgcgagc ctgctgctgc ccgtgtccaa cctgaccaac ctcctcgccg
      421 ccgaccgggt ggccctggag acccccgcgt tcgccgcccg gatgtggctg ccgcaggtcg
      481 ccgtcctcgc cgtcaccatg ctgctgctgt gggcgttctt ctggcggcgc ggcatgcgcg
      541 gcgccgacac ctacgacccg ccggacgtcg cgcccgtccg cgaccgcgtc ctgttctccg
      601 cgacgggcgc cgcgtgcctg ctgttcatcg gcgcgatcct cgcgggcgtc cacaccggcc
      661 tccagctcgg cctcgccgcg accgccgccg ccgtcgtggc ggtggccgcg ttcgccgtcc
      721 gcgaccggtc ggcgctgcgg ggcgagctgg tcccgtggcg gctgatggtg ttcgtgaccg
      781 ggctgttcct ggtcgtcccc acccttgagc ggtacgggct ggacgaggtg atgcgctccc
      841 tcgtcggcgg cgacgacggc gccgcgggcg ccgtcagggc cgggttcgcg ggggcggggc
      901 tctccaacgt cctcaacaac ctgcccgcct acgtcgcggg ggagtcggcg gtccccgagg
      961 ccaaccggga ccagctgctg tccctgctca tcggcacgaa cgtgggcccg gtgatcacgc
     1021 cgtgggggtc gctggcgacg ctgctgtggt tcgagtggtg ccgccgctgg gacgtgcgcg
     1081 tccccatgcg caagttcgtc ctcaccggga ccgtcctggc cgtactgggc tgcgccgccg
     1141 ccatcgcggc attgccggcg acccgctgac taccggacga gcgggatctg gccgtccggc
     1201 ccggcggtgt ccagcgcgcg gttcgcggtc tccacgagcc gcgcgagcag ctccgggcgg
     1261 gccgccacga accccagctc cgacggcgtg cggtcgatgc tcagctcgta ggggccgccg
     1321 tccaggcggc gcagctcagc gcccgcctcg gccgccagca gcgcgcccgg cggcaggtcg
     1381 acgagctcgg gccggtagcc gacgatgccg tcgatgtcgc cgcgcgccag catcgcccac
     1441 gcgaccagcg gcgcccacag ctggaggagc cgcgagcagc gcagctccag cgccgtgcgc
     1501 agcgccagcg ccgacgggtc gcccgccttg accgcgtggc cctgcgtcca gcccagcacc
     1561 gggttgcgct cccggccggg gcgcgggcgc ggcgccagcg tcagcggggc gccgtcgggg
     1621 tcgagcgcgc cctcgccgcg caccgccgtc cacgtccgcc ccgagacggg gtcgtggacg
     1681 acgcccagca ccgggacgga gcccgcgcac agcgccagcc ccaccgcgta cacgggcatg
     1741 ccgatcgcga cgttgttggt gccgtcgagg gggtcgacca gccagacgag gtgggagccg
     1801 tccgcgccgt cgagcacccc cgactcctcg gcgatgatcc ggtgcccggg gtaggcggcg
     1861 cgcagccgcc cgaggatcag ctcctcggcg gcggtgtcca gctcggtgac gacgtcgccg
     1921 ttcccgccct tgggccgggc gaccagcggg ccgcccgtgc cggcgcgcag cagcgccccc
     1981 gccgcctcgg ccgcatcgac cgccacccgg cgggcctcgc cgagatcgac cggtagggcc
     2041 ggtgacgctg tcgtggatct catcgggggc ctctccagtc gggtccgggg gctcggggtc
     2101 cggcggccgc ctaccggcgc gtcggtgaca ggtcgtcgcg ggggcgtccc ggcccgggcg
     2161 gcgcgggacg agcggcgtat gcgttcgcga cctcgcgggc cgaccggtgg agggcgcgcg
     2221 ccgcctcgcc cgggtcggac cgcgcgcggc gcacccggtg ggtcgcgacg tccggcgggc
     2281 cgagcgacag gtcgccgccc ccgggcgtct ggcggccgag cgcgaccgtg gccgcgtccc
     2341 gcccgtcctc gatcagcgtg ctgtggaaca cgcccgcggg cagagtgtac gactcgcccg
     2401 tcccgtgggc ggtggaacgg ccgggagagt atcggacggt gcgcccggtg gccctcagtt
     2461 cgtcgacctc gccccggctg acgacctcga agacctgcgc cgccgccccg ccggggccct
     2521 cgccgacgtc catccggacg ttgcgcaccg tcccgtacag gacgaagctc agcaggtccc
     2581 agctgtggca gtgcacgggc gaggtggtgg agggcgccgg gtcgacctcg gacgtccaga
     2641 tgtgcaggca cacgccgaag tcgccggcgc gctccaccgg caggcacagg aaccccaggg
     2701 gatgccgcac ggccgggacg cgggaccgcc cctccgcgac gtccgccagg acgcggcccg
     2761 cccacgccgg gagcgtccgc gccgccgtcc cggcctcgat ctccctgcgg atctcctcgt
     2821 acctcatcgc tcgcacccga tgtcgctgtt cctttgtggc gtccgcgtgc gtccggcccg
     2881 cgcggacgcg gtcactcgta ggggtccttg ggccgcagcg ccttcctgat gatctcgatg
     2941 acgtcccggt cggtgtagcc ctgggccatg tcgatgccga tcacctcgaa gagcctgcgg
     3001 acctcctcga cggtcggctc gtcgtccagc ggcgccagcc gcgcctgctc gaccggcacg
     3061 cggcgcgcct ggtccaggct cgtcagcagc tccgcgctca gccagctgta gtagaacttc
     3121 gtgctgtcga cgaccagcgc ctggccgcgc gggttgtcgc gggtgaccac gatcagcgag
     3181 gacgacaggt cgtagcgcag cgtcgtcatc gtccgcgcca gcccgatgtc gatgtcgagc
     3241 atcccgaacc gctgcttgtg ccagcacgcc gcgaggatcg tggcgtaggc ctccttgcgg
     3301 gtgcgctcca gcgtccacgg ctcgccggtg ccgtcgggcc cgtccgccga ggagcggcgg
     3361 tgccgcgcgt aggcctcgca gacctcgacg tccgtcgggt cgatgatctc cagccggaac
     3421 agcagcgtcc ggccgtcccg gcgggcggcg gcgacggtct cgggcagcgt cttggcgcgg
     3481 atgtaggtgc cggtgccgcc cttgaagatc cagcggtcgg tgtcgcggcg cgcctcctcc
     3541 agcacctgcg ccacctgcgc gccgctgatc acccggacga tcgtggtctc gtccagcgcg
     3601 cgcttggtgt cggccagcac gccctcgaac gtctcgatgt gggtcagctt gccgctcagc
     3661 tcgtccagcg tggccgagga cgcccgcagc gtgtcgcgca cctccgcctc gaccgggacg
     3721 cgccgccccc ggtcccgcag caccgacgtc gccaggaggc cgaccaccgc gaggatcgcg
     3781 ctgttggtga cctcgtcctc gtgggggagg tccaccccga ccccgagcac cgcgaccgtg
     3841 atggcgagga tcagcgcgat gaaggcgtcg gcgttcttcc cgagccacgt ggcgaagcgg
     3901 gtcattgtat gcgttttccc cgtccttgtc ggcgccgtca tcgtaaccac agcaccgcga
     3961 ggggggccac cggcccgcgt cccctacgcg gccggggctg aggcgccgca ggtcacgttc
     4021 ccctcgggcc gcggacgacc acgctttccg gcatggacga ccttggtccc ctccgccccc
     4081 tacactcatc gcatgcagct gcggggctgg tggtcggcgg catggccgac accgcgttca
     4141 cgggcgctgg acctcaccct cgcggtgtcg ctggcggtcg tggacggcgt gttcctgtgg
     4201 ttcgcccctc aggacttctg gctgccgccc gccgtgacgt cggtcggcag cttcctcctc
     4261 ggcctgggcc tggtcttccg caggcggcac ccggtccggc tcgcgctcgt cgccgtggcg
     4321 ctcggcacgg tcgcgggcgc gggcgtgttc gcgctggtgg tgatcctcta ctcgctggcc
     4381 gcctacaccc ccaaccgccg gacggtgtgg acgatcgccg ccgtcgggta cgtctccggg
     4441 atcgccttcc ccggccccac cgagagcgac gacccgttcc tcgcccaggc gatcttcggg
     4501 gtggcgttca cggccgtccc catcctgctg ggcctctata tgggggcccg caagcaacta
     4561 ctggcttccc tccaggagcg ggcgtcccgg ctggagcgcg agcagcacct cctcgcggag
     4621 cgcgcgcggg gcgaggagcg cacccgcatc gcccgcgaga tgcacgacgt cgtcgccaac
     4681 cggatcagcg tcatggtcgt ccacgcgggc gccctgaagg cgatcgccgt ccgcgacccg
     4741 ggccgggccg ccgagaccgc caccgtgatc ggcgacatgg gacggcaggc gctggaggag
     4801 ctccggcacg tgatcggcgt cctgcgccag ggcgaggagg cgctgcccca ggaggcggtg
     4861 acgctcgccc acgtccgcga gctggtcgac cagtcggggg cggcgggcct ggtggtcgac
     4921 ctggccgtgc gcggcgagga gcggcccatg ccgcccgccg tcgggcggac ggtctaccgg
     4981 ctcgtccagg aggcgctgac caacgtccac aagcacgcgg gcgccgccga cacccgcgtc
     5041 ggcctcgggc tgctccccga ggccgtcgag gtcgagatcg ccaacgacgc gcccaccgcc
     5101 ccgcccgacc acggcctgcc gagcggcggg cacggcctgg tggggctgcg cgagcgggtc
     5161 accgcgctcg gcggcagctt cgaggccggg cccagcgcgg acggcgggta cgccgtccgg
     5221 gcgcggctgc cgctgcccgc gtcctgatcg ccgtccggcc cgctgaccag cgcggaccgg
     5281 tttgtcggac gccgtgcgta cagtggggga gtagtcacag gggagggggg ccgggatgcg
     5341 gccagtcacc gatcttcggc gccgggtggc gcccttcgag gtcgtcaccg agatgacgcc
     5401 gtccggcgac cagccgcagg cgatcagcga gctggccgag cggatcggcc gcggcgacaa
     5461 ggacgcggta ctgctcggcg ccaccggcac cggcaagacc gccacgatcg cgtggctggt
     5521 cgagaagctc cagcggcccg tcctggtgat gcagccgaac aagacgctcg ccgcccagtt
     5581 cgccaacgag ctgcgcgaga tgatgcccgg caacgcggtg gagtacttcg tctcctacta
     5641 cgactactac cagcccgagg cctacatccc gcagaccgac acctacatcg agaaggactc
     5701 ctcgatcaac gacgaggtcg accggctgcg gcactcggcg accaactcgc tgctgacccg
     5761 ccgcgacacc gtcgtcgtcg cctcggtgtc gtgcatctac ggcctcggca ccccgcagga
     5821 gtacgtcgac cggatggtgc ggctccagac cgggcagcgg atcgagcgcg acgacctcct
     5881 ccgccagctg gtcggcatgc agtacacccg caacgacctg gcgttcacgc gcggcacctt
     5941 ccgcgtccgc ggcgacaccg tcgagatcat cccgcagtac gaggagctcg ccgtccggat
     6001 cgagatgttc ggcgacgaga tcgagaagct cgccaccctg caccccctca ccggcgaggt
     6061 catcaccgag gacgacgagc tgtacgtctt ccccgcctcc cactacgtcg ccggccccga
     6121 gcggatggag cgggccatcg ccggcatcga ggccgagctg gaggagacgc tcgccgtcat
     6181 ggagcggcag ggcaagctgc tggaggcgca gcggctgcgc atgcgcacca cctacgacgt
     6241 cgagatgatg cggcaggtcg gcacctgctc gggcatcgag aactactccc gccacatcga
     6301 cggccgcggc gccgggaccg cccccaacac cctcctggac tacttccccg aggacttcct
     6361 cctcgtcatc gacgagtcgc accagaccgt cccgcagatc ggcgcgatgt acgagggcga
     6421 cgcgtcccgc aagcggatgc tggtcgagca cgggttccgg ctgccctcgg cgatcgacaa
     6481 ccggccgctg aagtgggagg agttcctgga gcgcatcggg cagaccgtct acctgtccgc
     6541 gacgcccggc aactacgaga tgacccgcgt cggcggcgac gtggtcgagc aggtcatccg
     6601 ccccaccggc ctgatcgacc ccgagatcgt cgtcaagccc accaagggcc agatcgacga
     6661 cctcatccac gagatccggc tgcgcaccga caaggacgag cgcgtcctgg tcaccacgct
     6721 caccaagaag atgtccgagg acctcaccga ctacctcctc gaactcggca tccaggtccg
     6781 ctacctgcac agcgaggtcg acacgctgcg ccgcatcgag ctgctgcgcg agctgcgcgc
     6841 cggcgagttc gacgtgctgg tcggcatcaa cctgctgcgc gagggcctcg acctccccga
     6901 ggtctccctg gtcgcgatcc tggacgccga caaggagggc ttcctgcgct cggagacctc
     6961 cctcatccag acgatcggcc gcgcggcccg caacgtctcc ggccaggtcc acatgtacgc
     7021 cgacaccgtc accccgtcga tggagcgcgc gatcgacgag accaaccggc gccgcgccaa
     7081 gcagcaggcc tacaacaccg agcacggcat cgagccccag gcgctgcgca agcgcatcgc
     7141 cgacatcctc gactccctcg cccgcgagga cgccgacacc gagaccctca tcggcggcgc
     7201 gggccgccag cagagccgcg gcaaggcgcc cgtgcccggc ctcgcctccc gcacccgcga
     7261 ggtgggccgc cacgccgccg acctcgtcgg cgagcgcccc cgcgaggagc tggagggcct
     7321 catcgagcag atgaccgccc agatgcacca ggccgccacc gacctccagt tcgagctggc
     7381 cgcccgcctc cgcgacgaga tcaaggaact caagcgcgaa ctccgcgaaa tgaaggaggc
     7441 gggcgtcagc tagggcgctt ctgatgaatc ttgggcggac ccaacgagca acgtggttgt
     7501 tgctgctgtg gcagcaggtc gccgagaggt ggtttgtgga gccgttccag gacccgcaag
     7561 gtcgccctga tgatccatca gaaacgccct aggcccgctg gctgtactcg taaagtcccg
     7621 gctgttctca tgaagacccg gcccaccccc ctcgcctggc ggctcggggg gtgaccgtgc
     7681 cttggcgggc gcggcatcgc ttcgcgatct tcgcggtggg gcctcgcctc cggcgtcggc
     7741 cccaccgctc agccacgcgc ccgcgcggtg gtcgaggcca cttcggaaca cgccatgggc
     7801 tccggccctt ggcgccaccg tgccctccgc cgaccccgtc cgccgacccc gtccgccgac
     7861 cccgtccgcc gaccctgtcc gccgaccctg tccgccgatc gagcctgccg atcacgctcg
     7921 ccggtcacgc ctgctggtca cgcctgctgg tcacgctcgc cggtcacgcc tgccggtcac
     7981 gctcgccgac cacgcccctg acgtggtcgg ggacgtccgt gaccagggcg gccagggggc
     8041 ggcgggcaac acgctcgcgt tgccggggct gcctggctac cacccggcat ggctcggtcc
     8101 tcagcctcgg ccggcgtgct cacggccgct cccggtggtg gagcggtctc cccggcgcgc
     8161 cagccattgc gaggcgaggt cgcggtagta ggcgctagtc tccaggagtt gctcatgggt
     8221 gccggacgcg gcgatcctgc cctggtcgag gacgatgacg cccgccgccg cgcggacggt
     8281 ggtgaagcgg tgcgcgatga cgagcagcgc gcaccgcccg gcggcctcct cgatcgcgcg
     8341 gtgcagcgcc acctcgctct ccaggtccag atgcgaggtc ggctcgtcca gcagcaggag
     8401 acggggccgc gcgacgagcg cgcgggcgat cgccaggcgc tgccgctccc cgcccgacag
     8461 ctccctcccg tgctcgccga cgcgggtgtc cagcccctcg ggcagccgcg agaccagctc
     8521 gtccaggttg gtcatggcga ccgcccggcg gatctcctcc tccccggcct ccgggaccgc
     8581 gtagaccagg ttttcgcgca gggtcccgtc cagaaccggg cagtcctgct cgaccagccc
     8641 gatcctcgac cggtggccgt cgcggctcag cgagtcggcc cgcacgccct cgaccagcac
     8701 ctcgccgcgg tcgggatcat agaaccgctc ggcgagcgcg aagaccgtcg acttgcccgc
     8761 gccggagcgc ccgatcaggg ccacgtgccc gcccgccggc acctggaacg acaccccccg
     8821 cagcaccggc cgcccccgcc ggtacccgaa ccacacctcc cggaactcca gtgcggccgc
     8881 ccggccaccg ttcgcaccgg gctccgctac ggtgccgccc tgagcgcagg gcccggcgga
     8941 gacctcgtcc ccggcgagtc cgctggtcgc gccaggtggg cggggcagcg cggggaggcc
     9001 cggggcggcg tcggtctccc ggggcagtgc cagggcctcg gtgatccggt ggacggcccc
     9061 ggtgccctgc tggacggcgc tgaacgcctc gaagatcgag cccagcggcg ccgtcaggta
     9121 cagcatgtag agcaggaacg cgaccaggtc ggcgacggag cccgtgccgc ccgcgacgcg
     9181 cgtcccgccc accaggagga ccacgaggaa ggagccggtc accgcgagct gggtggcggg
     9241 ggagaccagc gcgtcgaaac cggccatccg gacgttcgcg gcataggcgg cctcggcgcg
     9301 cccgccgatg cgggcgctct cgcggggctc ggcgcgcccg gccttcacgg tgcggatcgc
     9361 gctgagcgcg cgttccagac cggcggccat ctcgccggcc gcctcccggc cccgcagcga
     9421 cgcggcccgc atgccccgca gcgcgagggc gagggccgtg cccgcgcccg cgacgacggc
     9481 cgcgacgcag gcgaacagcg cccagtccag ccagagcatc agcaccacgg tcgcggccag
     9541 gccgatggcg ccggtcacgg cgtcggtgag cccgcccgcg atgatctgcc gcagcgcgag
     9601 ggtgtccgcg tccgccctgg agatcaggtc gccgatccgg tgccggtcgt agacgggcat
     9661 gcggagccgc agcaggtggt cgatcaggtt cagccggacg ccgaggacga tcccctcgcc
     9721 ggtccgcgcg agctggaagc ggaccagggc ctgcaccagc gcctggccgg cgaacagcgc
     9781 gaccagcgcc cccacggcgg cccacggcgt ccggcccgac ccggcggccg cgatcacgtc
     9841 ccgcgcgacc aggggctggg ccagcgccag cgccgacgcc agcagggtcg ccgcgacggt
     9901 ggcggcgatg gcgccgcggt gcccggcggc cagccgcagc acctctcgcg gtcccgccgt
     9961 gctcctccgg tgcccggccc ggccgcccgg cgcgggcgcc tcagcgtcca cgggccccgt
    10021 cccggcgcgg tggcacggtg atcagcgcgg cgaggtagcc gtccggcacg ttctcctcca
    10081 cgaggcggcc ctcggcctcc acccacgcgt gcgccccgaa cggcggccgc acccgggcgc
    10141 cgacgcacca gctcggccac gcgccccaca tccggcacag caggacggtc gccagcgagc
    10201 ggggcaggca cccccgcggc ccgaggcagg cgaggctgcc ggcgaggacg gcgtcgcgcg
    10261 cccgcttcgc ctggtcatag gtggcggggg aggcgcccct ggagagcagg gtgaggagcg
    10321 tgcggatccg cgcgggcggc aggagggcga cgagccgggc cagcaggacg gccagccgcg
    10381 cggccgcgcg gcgccgcagc gggcccttcg gggggcgctc cagcgcgctc gggacggtca
    10441 cggccgcacc agtcccgccg cgcgcagctg tcccaccagc gccgtgacgt cccgcagcgc
    10501 ccgcggctcg tcgacgtcga actcctcggc catggccgcg gcggcctgct cggcggtgcg
    10561 gccgtccgcc agcagccgca gggccagggc ggcggtcgga ttgagctgcc agtagtcgcc
    10621 gctgcgctcg tcgaggagca ccgtgccgta ggcggtgtcg gtcgtggaca cgccggggcg
    10681 cagtcgcaaa cccatgcggg gtcttccttt cagtaccggt cttccggacg ggtcatcgcc
    10741 gcgcgcgccg gcggtccagg gtgcgcagcc agacctcgca gccgagcgtg gagtacagga
    10801 tcgccccgcg cagcgcgggc gtgtcgggac gggcgaggag ggccttcagc cgctcgccgt
    10861 cgacgaggcc gagccgggcc agccgggagt cctcgcacag ctccatcagg tcgcggctgt
    10921 gcgcgcgcag cccgtcggcg gcgtccatgg acgcctccgc cttgttggcg cgtgcgaggc
    10981 attcggccgg gacgacgccg cgcatggccg cgacgaggag cggcttgtac cgccacgggg
    11041 tgacccggtc ctccgcgcgc acggcgaggc aggcctcgat gacccggtcg tccaggaagg
    11101 gcgaggccat cggcaggccg gcgcgggcgc tcatccgctc ccactgccgg atgatgcggg
    11161 tacaggcccg gatcgagtgc aggtcgaggt gctgcccccg gtcgggggcc agcggctcgg
    11221 ccgtccgggc ggcctcgcgc agcacctgcg ccgccgcctc cgccgcctcg ggggtgaccc
    11281 agtcgaacag gcgcggagcc gtgtcccagc cgagcgcgcc cgcgacggcc gggcgggcgg
    11341 gggcgcggag gtcaccggcc gcgtccagga gccaccggcg gtaggggcgg ccgtcggcca
    11401 gggcgcgcgc cgccggggcg agcggccagt cgaacagcgc ccggaacccc cgcagccgcc
    11461 gcagcgcgag gagcggccgc ctgcgcagca gcccgtggta gtgggcctcg gagcaccagg
    11521 cgacgtggtc gccgccgatg ccggtcaggt gcaggcggct gcccctggcc gccagccggg
    11581 ggacgtggtc gagcatgcgg gcgcggtcca tcacgccgat gctcggctcg tccagcgggt
    11641 cgtcgatctc caggagcccc gcgtagacca gcgacgcgtc ctcggcgggc cacaccgcgt
    11701 gctcgacacc gggcaggtgc gcggcggcgc ggcgcgccca ggccaggtcc tcgtcggccg
    11761 gatcgcggcc gggccaggtg gcggcgacga cctcggcctc gccccgggcc gccaggaagc
    11821 agatcgaggt cgagtccagg ccgccggaca ggtcgcagct cacgacgccg ccgcccgcgg
    11881 tgcgcgcgtc gaccgccgcg gtgagcgccg ccgcgacctc gtccgcggcg gtggcaagcg
    11941 ggcgcaccgc ctccggcgcg gcccaccagc ggcgcgtccg cgcgcggccg tccggctcca
    12001 gcagcaggtg ggcacccggc tcgacgccct cgaccccgcg ccacagcggt gtgtggagca
    12061 gcgggtgcgg gagcggccac agcaggcgcg cggcgacctg gcgctcgtcc agcgcggccc
    12121 cggtcagggc cgcgagcgtg tcggcgcggt cggcggccac cgtgacgccg cccgcgcggg
    12181 tgtggaagac cagccgcagc ccggcggcgt cgccctggac gcgcgtccgg ccgtccagcg
    12241 cggcgaccag gtggaagctt cccggcaggg agcggacgag ccggtcgagg gaggcgaggt
    12301 cgcgcagccg cccggcctcc cgggcgagcc gctcgggacc gatcgggcag gtgccgatga
    12361 tcgcgatccg ggcgtctccc gccgcggcct cggtcatctc ggcgtcgctc cagcggcccg
    12421 ccagccaggg ccgcccggag cggtgccgca ggatgcgttc ggggggtgtg ggcaggcccg
    12481 cggccacggc gagggccgcc tcgtggtccg gaaggaccac gaaggacgcc tcgccgtggc
    12541 ccggcatgcc atcgtgatca ggcatgggcc gtgaacgccc ggctcagttc ttgctgagga
    12601 tcacacggtc gttgccgtgg aagccgagca gcccggtgac cttgcggaag gagccggccg
    12661 ccacaagggc gggggtctcg tacttctgca ttttctcctc ctcttgccgt gggtttccca
    12721 ggggagatct cccgtgttcc gccttccgct cttctcggtg gaatgcgaaa cgcgagaagc
    12781 atgacatccg ggcgcgccgg ttgaccatcc cgccgatatc cgatcttcat ggcgccggag
    12841 cgatcgatgg cggcttcgaa gaggagaaaa cgggataagg caaccatacc cggtggtatg
    12901 gggcttccgg taaatcggat tacctgtccc tgcggacatt gttcggtgcc acaggcgaag
    12961 gatcatatta acctgtccgt aacccagaat gatgccgctt ggtgcaaata cgcgacctat
    13021 gaggacgggt gtgcgcggtc caatatccgg tcgcgtcgaa cggggggcgg gaggtcgtcc
    13081 tccctttggt ccgaccttcg ccccgcctat cgccccgctc tttgtaccgg cctttgttcg
    13141 ggttcttggg aattcccctt gacccgtcct ttaggtgcgg gagcccgagg ggcggctacg
    13201 gcttgagggc gaagaactcc cgcacgcggc gccggtggta gtcgagatcg tcctcgtcgt
    13261 gctcgacgcc tcgcgcgcgt gccaggttga agtaggcggt ctcgcgccgg aggcggtggc
    13321 ggatgagctg ggcgacggtc tcctcgtcca tgggcccggc ggtgccgccc gccgcgtggt
    13381 agtcggcgac gaagcggcgc cgcagctcgg gggcccgcgc gtgctcgtcc gtccattcga
    13441 gggcggcgga ggccacctcg aactcggggg cggcgacgaa cgcctcgtcc cagtccagga
    13501 gggcgaccag gcggccgccg cgcgccaggg tgttgccctc gtagtagtcg ccgtggacga
    13561 cctggcgcgc cggggtgcgg gcgtggaagg ccgcgagcca ccggtcgagg tcggggtcgg
    13621 cgagttcggg gacgtcctcg gggaaggcgc cgtccaaccc gatctcggcg aaggagcggg
    13681 tcggacgcgg cggcggggcg tggtcggcca gcgcccggtg cagccgggcg aggagcgcgg
    13741 cggcctgcgt gcgcgtcgtg ggctcctcgg tgtcgggcca ctcgccctcc acgtggcgcc
    13801 acagcgacag cgggcggccg tcgccccgga cgaccgtggc gccgtcgcgg gcgcgcagcg
    13861 gcgccaccgc ctcgggcatg cgggacgcgg cgtgcgccgc caccgcgtgg caccactcgg
    13921 tctcggcgtc gctccgccag gcggggccga cgcgcaccac gagagcgccg atccggtacg
    13981 cggccgactc ctcgccgccg aacagccgct cggcggggcc gtcggcggga acgttccaag
    14041 catcctggac cgccttccgc atggcgcccg tgagcggcgt ctcggcgtag atcatcctgt
    14101 ctccttccgg gggtccaccg atcggtggac ggcaggttca gccgttcgcc gctgccgggg
    14161 aagggggccc ggccagcagc atcgagcaca tgatgaatct tccagtacgc gcggcccggt
    14221 ggagcgccgg gcacccctgg cgggcgatcg ccggatggtt cctgttcgtc gcgctgtgcc
    14281 tcggcgtggg catctcggtg ggcggccacg ccgccacgtc cgcggacttc cgggtcggcg
    14341 aggccggccg ggcggaggcg atggcggccg agggcgggct ccagaacaag cccgtcgagc
    14401 gggtgatgat ctcgggcgag ggggcccggg acgccgccgc gcgcgacatc gcgggccgga
    14461 tgaaggggct gccggaggtc gagtcggtcg ccgcgccggt gcgggccccc ggcggggacg
    14521 tcgtccgcgt cgacgtgacc ctcaagggcg ccgagctgga cgggcgcaag cacgtcgagc
    14581 cgctccggga gcagaccgac gcggtgcggg ccgcctaccc ggggctgcgg gtggaggaga
    14641 ccggcgggcc gtcggtcagc aagggcgtcg aggagctgcg cgggaaggac ctctcgcgca
    14701 ccgaggtgat cgcgctcccg gtgacgctga tcacgctgct gctggtcttc gggtcggtgg
    14761 cgctcgcggt ggtgccgctg ctgctggcgc tgtcgtcgat cgtcgcggcg gtgggcctgt
    14821 cgatgctcgc ctcgcacgtg ttcccggacg cgggggtcgg cacgaacgtc atcctgctga
    14881 tcgggctggc cgtcggcgtc gactacaccc tcttctacct caagcgggag cgggaggagc
    14941 gggcccgcgc gggcggacgg ctcagcccgc gggcggtggt ggagctggcc gcggcgacct
    15001 cgggacacgc cgtggtggtg tccggcctcg cggtcgcggt gtcgagcgcg acgctgttcc
    15061 tggccgacga cgtgatcttc tcctcgctcg ccaccggcgc gatcgtggtg acgctggtcg
    15121 cggtggccag ctcgatgacc gtcctgcccg cgctgctcgc gaagctcggc gcgcgggccg
    15181 agcggcgccg ggagcgcagg gcgcggcgcg gcaaggccgt ccgggcgcac cgcgaggacg
    15241 gcgccgggcg gatcaccacg gcgctgctgc gccccaccga gaagcgcccc gcggtcaccc
    15301 tggccgtcgc cgtgctggcg atgctggcgc tcgcctcccc gctgctcggc ctcaagctca
    15361 cggacatggg ccgggagacg cacccccgca gcatccccgc cgtccagtcc taccaccgca
    15421 tgaacgcggt gttcccggag ctgaagtcca cgcaccaggt cgtcgtccgc gccgacgccg
    15481 gacggtcgga cgaggtgcgc gccgccctcg gcgacctcgc cgggcgcacg cgcggcgacc
    15541 ggcgcttcgc gggcgccccg agcctgcgca cctcggcgga cggccgggtc agcctcctgg
    15601 agctgcccgt cccgcactac ggcagcgagg acgcggcgcg tgcttccctg cgcgacctca
    15661 ggaagcggta catcccggcc tcgctcggaa agctggacgc ggacgtcgcg gtgtccgggg
    15721 acgtcgcccg ctacaccgac taccccgagc accagaagga caagctgccg atgatcatcg
    15781 gggcgctgct gctggtgacg ttcgcgatga ccgcgtgggc gttccggtcg gtggtgctcg
    15841 gcctggtcgg cgtcgtgctg aacctgctgt cggccgccgc gtcgctcggc gtgctggtgg
    15901 cggtgttcca gtacacctgg gcggagggcc tgctcggctt cacctcgacg gggtcgatcg
    15961 gctcgcgcgt cccgctgctg ctgttcgtga tcctgttcgg cctgtcgatg gactaccagg
    16021 tgttcgtgat cagccgcatc cgggaggcgg ccctggccgg ggtgccgacc cggcgggccg
    16081 tcctggaggg cgtcggcggg tccgcgcggg tcgtgacgag cgcggcgttc gtgatggtga
    16141 cggtgttcgc gagcttcgtg ccgctgcaca tcatcgagat gaagcagatg gggttcagcc
    16201 tcgcggtcgc ggtgctgctg gacgcggcga tcatccggat catgatcctg ccggcggcga
    16261 tgctgctgct cggggagcgg agctggtggc cctcgcgggg gatgcgccgg gtgcgggccg
    16321 cggcggagcg ccccgccgaa aaagtaggct gaccggcatg gacgcccggc cgcagctcga
    16381 cgatcggttc caggtccgcg ccctcgtccg gtggtacgcc gcgctgtggc tcgtgctggg
    16441 gttgatcccg caggtcctcg ccgcggccga cgaccccggc gcggcgcggg tctcggggat
    16501 cgtgctgccg gtcgtgctcg gcgcctgcta cgcggtgacg gagctgtacc cgcgcgtgct
    16561 gccgccgatg gcgtacctct gcgtgctcgc cgccggtgtg ggcgccctgt cgtacgtgcg
    16621 gggaggcggt gcctcgctct acatcgcctc cctcccgcag ttctggatcc tcaccaggag
    16681 ccagcggtac gcggtcgcgc tgagcggcgc cgccgggctg gcgacgctgg ccggggaggt
    16741 cgcggcgggc gccgcgcacc tcccgaccgg caacatgctc ttcaccgtcg gcgggttcct
    16801 ggccgggctg ctgctcggcc tggcggcgca ccggtacgtg cggcagaccg aggagcgggc
    16861 gcggcggctg tcggcggagc tggcggtggc gcagcgggag ctggccgagg cgaaccggcg
    16921 gcagggcgcg gcggaggagc gcgagcgcct cgcccgggag atccacgaca cgctcgcgca
    16981 gggcttcgcc tcgatcatcg tgctggcgga ggcggcccgc gcggggctcg gcgccgagcc
    17041 gggccgcagc gagcagcagc tccgctcgat cgagcggacg gcgcgcgaca acttcgcgga
    17101 ggcgcgcgcc ctggtcgact ccgcgcggcg cgacggcccc gcgcagggcc cggtcgcggc
    17161 gacgctccgc cgcgtcctgg accgcttcac cgaggacacc ggcatccccg tcggcgcgga
    17221 gctgcccgac gtcgagtgcg accagccggc ccggatcgcg ctgctgcgct gcacgcagga
    17281 gtcgctcgcg aacatccgca agcacgcggg cgcctcgtcg gtcggcgtcg tgctggagcg
    17341 ccacccgcac ggcgtcgagc tggagatcac cgacgacggc cgcggcttcg tggtcggcgc
    17401 cgccgccggc ttcggcctgg agggcatgcg ccgccggctg gccgagctcg gcggtgagct
    17461 gaccgtcacc agctcggtcg gcgacggcac ccggatccac gtgatgatcc cgctgagccc
    17521 gcaggacccg ccgacccccc tgatctcgac gagcccgcag gagtgacatg accgaccgca
    17581 cgctccgcgt catcgtggtg gacgaccaca cggtgatgcg cgccggggtg gtggcgctgc
    17641 tggccaccga gcccggcatc gagatcgtcg gcgaggcggg cgacggccgc gcggccgtcg
    17701 acctcgccgc ccggctccgg cccgacgtgg cgctggtcga cctgcggatg cccgtcctgg
    17761 acggggcgag cgccaccgcc gagatcgtcg cgggcgcgtc ggggacgcgg gtgctgatcc
    17821 tcaccaccta cgacaccgac gccgagatcg agcgggcgat cgaggcgggc gcggtcggct
    17881 acctgctcaa ggacaccacc cgcgagcggc tcgccgacgc gatcaggtcg gcggcgcgcg
    17941 gcgagaccgt gctcgcgccg cgggtcgccg agcgcctggt ggcgcggatg cggcggcccg
    18001 cgcaggtgcc gctgaccgcg cgcgaggtgg acgtgctgaa cggcgtcgcc gacggcctgt
    18061 ccaacgccga catcggccgg cggctcgtga tcgcggaggc gacggtgaag acgcacctgc
    18121 tgcgggtgtt cgcgaagctc gacgtcagcg accgcacgca cgcggtggtc gtggcgatgg
    18181 agcgcgggct gctgccccgg ccgcgctgac cctcccgggg ccgcccgcgc gaacgtcccg
    18241 gaagtgtcgc gcgggagtcc gggaaggcgg ccccggcggg gacctaccat cgccgtatgg
    18301 agtacgaggt gcgcctggcg cgacccgccg atctggcggt gctgccggcg atcgagaact
    18361 cggccgaccc gctgttcgcc ccgctcggga tcgtgttccc gccgggcccg acggtgatcg
    18421 agcagatgga cggcgcggac gtggagatcc tcgtggcggg cgacccgccg gtggcgttcg
    18481 ccgccgtcga ggaggtggac ggcgcgaccc acctggagca gatctccgtg cggggcgacc
    18541 tggtgggccg ggggatcggc acccggctgc tggcgacggt gcgcgagcgt gcggccgccg
    18601 ccggctcgcc gggcgtcagc ctgctgacgt tccgcgacgt cccgtggaac gggccatggt
    18661 atgccgcgca cgggttcgcc gagctgcccg aggagcgctg ggggcccggc ctgcgcgcct
    18721 actggaaggc cgagatcgag gcgggcctgc acgacctggg cccccggacg gtcatgtggg
    18781 cgccgtcccg ctgagcgccg ccccggcacc gccccggcac gtaatgtggt ctcccggaga
    18841 cccgccgggg acggcggtgc gccactaaaa atctacaatg taaaggtggg aaccggtgac
    18901 gtcgcgcgag cgtcagcctg agggagccgg aggaggacga tgacgggtcc ggggtcatgg
    18961 gcgcggtggg cgcgcggacg tttcggcgag cgggggctcg cgctgaccgc gctggtggcg
    19021 ttgctggcgc tggcggtcgt cccgctggtg gcgctgccgg ccgtccgctg cgaggtgttc
    19081 gggagcgggt gccgcacgcc gccgcccgag gtccgcgccg acccggtgtc ggcgccgggc
    19141 cgccagttca ccccggtgga ggcggcgacg cggggcggct acgtcgcgct cggcgactcc
    19201 tactcctccg gtgtcggcgc cgaggcgacc gtcggcgaca acaacccgct ggagcgctgc
    19261 caccggacgt ccaaggcgta ctacaacgag gtctccaagg cgttcccgtt cgccaagggc
    19321 acctcgttct gggcgtgctc gggcgccacc acggcggaca tccgcgacgg caggcacggt
    19381 gagccctcgc agctcggccg gctcaacgcc gacacgagcc tcgtcacgct gagcgtcggc
    19441 ggcaacgaca tcgggttctc caaggtcgtc gcgggctgcg tggtgaagct gccgtggagc
    19501 aggagctgct tcaggcaggg cgacgacatc gccaggaaga tgtccgacct gcgccgcaac
    19561 ctgcccgagc tgatcggcca gatccacgcg cgcgccccgc acgcccgcat catcctgatg
    19621 ggctacccga aggcgttctc cgaggtggag ggcaccggcg gcgacaacct cagggtgtcg
    19681 gagcagcagt ggctcaacgc gcgcgcctac gacctcgggc ggctcatccg ggagaccgcc
    19741 gccgaggccg accgccgcat cgccgcccgg caccagcagg gcagcgtcga gttcgtcgac
    19801 tcctacagcg cgttcgcggg ccacgaggtc ggcagcggcc agccgtacat gaacggcctc
    19861 acggtgaacc tgtcggccct ggaggccgag ccgcgcagct accaccccac ggtgagcggc
    19921 cagcacgccc tcgccgggct gttcatcgag caggtcaaga aggggccggg ccgccccgtc
    19981 tcctagcgcg ggtcctgccg ggggagggag cgttcgacgg cgtcggcgac gaggcgccgc
    20041 acgtcctcct cggtgaacac ctccggcagg gtcaggttct cgacgatcag ccagttcagc
    20101 gtcaggtaca gcagccggac ggtggtggcg tcgcccggca tgcccgactc caggtgccgc
    20161 gccacgttcg cctcgacgtc ctcgcgcacc cgctcggtca ggacggcgcg cagcccgggc
    20221 cgccgggtgg cctccagccg cagctccagc agggcgaggt agccggtccg gaacgccgag
    20281 atccggtcga cggtctcggt cagcagcgcg gtgacccggg ccaggtcgcg ggggccctcc
    20341 agcatgccgc cgagcgtggc cgcgtccggc tggagccgct cgtagatccg cccgcccgcc
    20401 tgcgtgaaca ggtcgtcgcg cttggcgaag tagttggacg cggtgccgac gggcacgccg
    20461 gcctcggcgt ccaccgcgcg gaacgtcagg ccgcgcgcgc cgtccctggc cagcacctcg
    20521 atcgccgcgt cgaccagggc ggcgcgccgc tcgacgttct tcctcacttg acaccactcc
    20581 agacgtagta ctacgtttaa accacttcaa gtagagtact acgaacggaa tcccctatgc
    20641 gcaagctcgt ctactacgtc ggaacgagcc tcgacggctt catcgcgggc cccggcggcg
    20701 agatcgactt cctgccggtc agcgaccagg tgatggcctg gatcggcgag cgctaccccg
    20761 agacgctccc gacgcacgtc cgcccgcacc tcggcatcca ggacgcgccg aaccagcgct
    20821 tcgacacgct cgtgatgggc ctcgggacct accggccggc cctcgacatc ggcgtgacca
    20881 gcccctacgc gcacgtccgg cagtacgtcg cctccaccac gctgcccgag atcgccgacc
    20941 ccgccgtgac gctcgtccgc gacccgctgg agctcgtccg ctcgctcaag gccgaggacg
    21001 gcggcatgga cgtctggctc gcgggcggcg gcaggctcgc cgccgcgctg ctgccggaga
    21061 tcgacgagat ggtcgtcaag agctacccgg tggtggcggg ggcgggcgtc cccgccttcg
    21121 cgggcgggtt ccggccgacc cggttcacgc cgacggcgcg cgaggagttc gacaacggca
    21181 cccaggtcac ctggctcacc cgcacgcccc agcccgcatt ggggtcccgg ccgctcgcgc
    21241 atagggccct agggccctac ggcgggtgat cacgagccct tagcctcgtc ggcaccggcg
    21301 gatcgcgagg tgtcgagggg gcagatgatc tgggtgaggc cggcgctcgg cctgctgtcg
    21361 gccgccgtgc tcgtgccggc cgtcgcgatc gtggggtacg gcgcggtgga gggggtgtcc
    21421 gtcccgctgt cgatgtctac ggtctcggcg acgtcggcgc agcggaacgg gcggggcgcg
    21481 gccaggggga cccgcggcct gcgctacgtg aagacgttgc gcgggcaggg cgtcagccac
    21541 ggcacggtca cggtcggcgc gcgaggggtg gtggtgcggg gcacgcaccg ggacctgcgc
    21601 tgcgaggacg gcccgtccta cctgaagatc accgtggtgc tggccgggct gcccgacgcc
    21661 gagcacgcgg cgggcctcgc ctgcgggcag acccgcgagg tcgccttcgc ctacgcctgg
    21721 acgggcgcgt cctcggccgt ccacctccag gtgtgcggcc gccgccgcga cgcctgcggg
    21781 ggccgcagca cggtcctgcg gccggggtga ggcgtcagca cggccgcagg ccctcgaccg
    21841 gcacgccgcc gccgaggcgg ccgcagatcg cggtgggctg cggccggccg tccttcaggg
    21901 tgaccttgac gagcgtgagg ccccggttgc ggggccgcgg cgggtccccg tggtcgttgg
    21961 tgaagtcgat gtcgccggtc gccgagccgc cccgcgtgat ccgcaggtgc cgcagctcct
    22021 ccagcaccgt cccggacgtg acggaccgct cgcccgtcac cagccggggg ccgagcaggt
    22081 cgtaggcgtt ctgcgcggcc tggctcagcg cgaacgtggc gtcgaaagtg atggccatct
    22141 ggccgtccac cagcagcggc tcgtcgggcc ggacgcgggg ggcgccgatg ccgaagcggt
    22201 tgcgggccat gaggaagaag tcgccggtca cgtcggcgtc cttggcgatc aggtggggca
    22261 ggtaggcgaa cacggtgtgg tacagggtgg tgttctgggg gagcggcacc tcgtgcggac
    22321 cggtgccgaa gcgggacttg ctgacgtcgt cccccgcgat caggagcagg cggtgccggg
    22381 tgcagccgcc ctggacgagg ccgttcatca ggccgggcag gtcctcggca cgcccggcga
    22441 agtacacgag ggtgtagggg agccggccgt tgtcgcaggc ggccttgacc ttgctggaga
    22501 tgtcgccggg gccgcggtag ccgacggtgt ggggggcgcg cggccgcagc acgctcacga
    22561 cgtca
//
