LOCUS       NZ_JAHFZY010000001     22512 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Actinomadura sp. NEAU-AAG7 Scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_JAHFZY010000001
VERSION     NZ_JAHFZY010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura sp. NEAU-AAG7
  ORGANISM  Actinomadura sp. NEAU-AAG7
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 2046061)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Actinomadura oryzae sp. nov., a novel actinobacterium with the
            activity of releasig potassium isolated from rhizosphere soil of
            rice in Sanya
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2046061)
  AUTHORS   Xu,X. and Zhao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2021) College of Life Sciences, Northeast
            Agricultural University, 600 Changjiang Road, Xiangfang District,
            Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018603865.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:10:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,952
            CDSs (total)                      :: 7,871
            Genes (coding)                    :: 7,813
            CDSs (with protein)               :: 7,813
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 6 of 58
            Pseudo Genes (incomplete)         :: 53 of 58
            Pseudo Genes (internal stop)      :: 1 of 58
            Pseudo Genes (multiple problems)  :: 2 of 58
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:01:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 932409
            Orig. end                         :: 954921
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHFZY010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22512
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="7"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22512
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22512
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12512](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12512
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            11..1093
                     /locus_tag="KLI87_RS04375"
                     /old_locus_tag="KLI87_04380"
     CDS             11..1093
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631862.1"
                     /locus_tag="KLI87_RS04375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04380"
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="WP_214615914.1"
                     /transl_table=11
                     /translation="MAMTRVRPSGLFKTRGRPTAAPIRPRDSAVIDWAAYIDGHRASTA
                     TVEDAVRLIRDGRLTADGDSAGFVWVGLHEPSATELTELAEVFGLHPLAVEDAIHAHQR
                     PKLERYDDVHFVVMKTVGYVASGPGGAEVVETGEIMIFCGPDFVVTVRHGAHGALGPVR
                     EQLERDPARLGKGPAAVLHAVADRVVDGYVCVADAVQEDIDEVEEAVFSPERTDESRRI
                     YRLKREVIQLKRAVGPLAGPLRNLSGRRFVPAEIKEYLRDVEDHLTRVREQVESYDELL
                     NPILQAHMTQVTVADNQDMRKISAWGAIFMVPTAIAGVYGMNFDFMPETQWRYGYPLIL
                     AVIGLACLSLYRGFRRNGWL"
     gene            complement(1260..2105)
                     /locus_tag="KLI87_RS04380"
                     /old_locus_tag="KLI87_04385"
     CDS             complement(1260..2105)
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631865.1"
                     /locus_tag="KLI87_RS04380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04385"
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="WP_214615915.1"
                     /transl_table=11
                     /translation="MTRTVEVHGHRGARGLRPENTLPGFAHALALGVDAVELDVGLTSD
                     GAVVLVHDQVLSPVTLSDTRPARPGDPAFPYVGKAVGDLTLEQLKTVDAGVRRRDDAFT
                     ATQLPLPGTPVPTLAETCALLAPSEVRLSVELKTDPTWPDEDIALFVSAVASVLEGAGV
                     TRRSRLLAFDWRVLAEAHRHPALGRVALVERKTLVPGTAWLAGLAPDDPVAAATAIGAT
                     ALSPEHTLITPALVDDAHAAALPVIAWTVNEPEDMSRLTKYGVDALVTDYPDLALAVRA
                     "
     gene            complement(2166..3449)
                     /locus_tag="KLI87_RS04385"
                     /old_locus_tag="KLI87_04390"
     CDS             complement(2166..3449)
                     /EC_number="6.3.4.4"
                     /GO_function="GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011293429.1"
                     /locus_tag="KLI87_RS04385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04390"
                     /product="adenylosuccinate synthase"
                     /protein_id="WP_156220200.1"
                     /transl_table=11
                     /translation="MPAIVLVGAQWGDEGKGKATDLLGGDVDYVVRYQGGNNAGHTVVI
                     GDKSYALHLLPSGVLSPDVVPVIGNGVVIDPAVLLQEIDGLRDRGITCERLLISGNAHL
                     IMPHHRALDKVTERYLGKARIGTTGRGIGPAYADKINRMGIRVQDLFDPNILNQKLDLS
                     LREKNQVLTKVYNRRRIETGPIVQEYLAYGERLRPFVADTSLVLNKALEDDKVVLLEGA
                     QGTLLDLDHGTYPFVTSSSPTAGGACAGSGIGPTRISRVIGILKAYTTRVGSGPFPTEL
                     LDEQGEFLRTTGGEYGVTTGRDRRCGWFDAVIARYATRVNGITDYFLTKLDVLSGLERV
                     PVCVAYEIDGERVEEMPTTQTDFHHAKPVLEHLDGWKEDITAAKTFDDLPKNAQAYVRT
                     LEEMSGAQISAIGVGPGREQTLSLRPLI"
     misc_feature    3581..3595
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            complement(3595..4005)
                     /locus_tag="KLI87_RS04390"
                     /old_locus_tag="KLI87_04395"
     CDS             complement(3595..4005)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850593.1"
                     /locus_tag="KLI87_RS04390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04395"
                     /product="DUF3151 domain-containing protein"
                     /protein_id="WP_156220199.1"
                     /transl_table=11
                     /translation="MTHNLLGGVPPTELPDNAEAREALANDVDPFEVAARHPDYPGAWA
                     ELADRAFARGGVIDSYAFARTGYHRGLDQLRRAGWRGQGPVPWEHEPNRGFLRALHALG
                     RAAAAIGEDDEAERCRTFLSDSSPTAADVLGG"
     gene            complement(4082..4609)
                     /locus_tag="KLI87_RS04395"
                     /old_locus_tag="KLI87_04400"
     CDS             complement(4082..4609)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850594.1"
                     /locus_tag="KLI87_RS04395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04400"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_214615916.1"
                     /transl_table=11
                     /translation="MTKLGVRPTAHLAPPALEDVRIRPYGITDGPRLRRMSERLSKTSL
                     YTRFFSGTPHIPEHYVRLLERLDHWDREALVALDGDEIAGVAEYSRDRRRPWSADLAVL
                     VTDPWQRRGVGSALVRCLAPLAARRGITEFEADVILGNRDALRFVRHGWPAAHASNADG
                     AAHFRLPLPVRA"
     gene            complement(4656..5105)
                     /locus_tag="KLI87_RS04400"
                     /old_locus_tag="KLI87_04405"
     CDS             complement(4656..5105)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850595.1"
                     /locus_tag="KLI87_RS04400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04405"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_214615917.1"
                     /transl_table=11
                     /translation="MALPRTYESQNCSIARSLEIVGDRWTMLVVRAAFEGVRRFDDFQD
                     VLGVARNVLTDRLSRLCDEGILRRVPYQDRPERFEYRLTRKGVELWPTMMSLMAWGDRH
                     YAPDGPPTLIGHRGCPGTLTANFTCDACGASLGPADVEPRPGPGR"
     gene            complement(5177..6199)
                     /gene="fbaA"
                     /locus_tag="KLI87_RS04405"
                     /old_locus_tag="KLI87_04410"
     CDS             complement(5177..6199)
                     /EC_number="4.1.2.13"
                     /GO_function="GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fbaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014912124.1"
                     /locus_tag="KLI87_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04410"
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="WP_156214724.1"
                     /transl_table=11
                     /translation="MPIATPEVYAEMLDRAKQDGFAYPAINVTSSQTLNAALRGFAEAE
                     SDGIVQVSTGGAEYLSGATVKDMVTGASALAEYARVVAAKYPVNIALHTDHCPKDKLDG
                     FMRPLVKISQERVARGEEPLFQSHMWDGSAVPLEENLQIAAELLDQCAKARIIMEMEIG
                     VVGGEEDGVANEINEKLYTTPGDALATAEAVGVGERGRYILAATFGNVHGVYKPGSVKL
                     RPEVLKGIQDAVGEKYGKEKPFDLVFHGGSGSTLEEIREAVSYGVVKMNVDTDTQYAFT
                     RPVADHMLRNYDGVLKVDGEVGNKKQYDPRSWGKAAEAAMAARVVEASEHLLSAGKRLK
                     "
     misc_feature    complement(6215..6228)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.22"
                     /tool="antismash"
     gene            6518..7261
                     /locus_tag="KLI87_RS04410"
                     /old_locus_tag="KLI87_04415"
     CDS             6518..7261
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631871.1"
                     /locus_tag="KLI87_RS04410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04415"
                     /product="DedA family protein"
                     /protein_id="WP_214615918.1"
                     /transl_table=11
                     /translation="MDLTTLPLDITEYLHPTAWLQLFGTFATIGVLAIIFAETGLLIGC
                     ILPGDSLLFTAGILTAVSTVNGQEFQSLSLPWLLIGGPLAAIAGAQLGHWLGARYGRKL
                     FERPDSKIFRQEWVEKAEYYFNRFGPAKAVVLARFIPIVRTFLNPLAGMLGMDSRKFLI
                     WNVVGGVIWTDTLFLLGHFLGSEVPDVERYILPGVAVILVLSVIPIIREVMKGRRASRG
                     GGKHSRPKNNGPEESRPSLSGDSYR"
     gene            7355..7741
                     /locus_tag="KLI87_RS04415"
                     /old_locus_tag="KLI87_04420"
     CDS             7355..7741
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLI87_RS04415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLI87_04420"
                     /product="hypothetical protein"
                     /protein_id="WP_214615919.1"
                     /transl_table=11
                     /translation="MAGGLSLVNAVSGDSDNHDPATVSPSPGDGGGQNRSAPSRSPSSS
                     ASGALPLVIRVTGPATNVVVRVATTGEILTQALLSTGDTRKYEQTPLQVVATNGGALEV
                     MIYGRKWPPKPSGSRGQWFVSAKK"
     gene            complement(7752..8258)
                     /locus_tag="KLI87_RS04420"
                     /old_locus_tag="KLI87_04425"
     CDS             complement(7752..8258)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012859.5"
                     /locus_tag="KLI87_RS04420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04425"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_214615920.1"
                     /transl_table=11
                     /translation="MRGSSMFALLPVVVMAGGLWAGSSASAAPSPRPETRRDLAGVLIK
                     PVAAKDLCLEVADDNSGNGALVTLYTCTGRDNQRWTLDGGMIRTGLPGHRCLDVRTGNG
                     RNGAATNIYDCNNTRGQQWHFVGDKLASGINGTCLTVVAGNFAPGGGVLNWECVVSQDQ
                     AWEVS"
     gene            8410..9450
                     /locus_tag="KLI87_RS41410"
                     /old_locus_tag="KLI87_04430"
     CDS             8410..9450
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="KLI87_RS41410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04430"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_156214721.1"
                     /transl_table=11
                     /translation="MSAGRSAPAALAGAATEIGSAAELGAVVSRWVGRAVPHEGYMLAA
                     VDPVTGAGCFLAREHGYSPAAARRLTLGDRRERDHPFPFERLVEGPCHVGVLNTDAPGR
                     RRNAAMRAVMTDLGVGSELRLALVDGGTTWGGLVLLRPRGARPFSPDEASRAQRLARDI
                     VAALRRYATGAPPEPNRLDAPPGVLVIDPDETVTAATPSARAWIRELETLPPAALAAPD
                     LPLESTIWHLTQAARSDGSGRATLTRVPTRRGWVAIQAQPMPTGAVAVTIQAAAGKELL
                     PAVAFWRGLTPREHMVVDHMLKGLSSKQIARHLRLSPHTVNDHLKSIYRKTGVSTREEL
                     LARFLD"
     misc_feature    complement(9556..9569)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            9703..9828
                     /locus_tag="KLI87_RS04430"
                     /old_locus_tag="KLI87_04435"
     CDS             9703..9828
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="KLI87_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04435"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_156214720.1"
                     /transl_table=11
                     /translation="MSMAYEPPAFVVIGDLREVTLGDKTWGFDRINQCAFYNCVQ"
     gene            10001..11839
                     /locus_tag="KLI87_RS04435"
                     /old_locus_tag="KLI87_04440"
     CDS             10001..11839
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="KLI87_RS04435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04440"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_214615921.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.1e-41, bitscore:
                     139.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFFVVPDNSEGALLAASLHTRWPDLRVLPHDSGRPWVVGRWQDE
                     EVRWAAAGARRIALLGRVQASAPWLTEYIAGQRDLGALADLRRELPGSYHTAAVMDRVV
                     FVQGDLSTVREVFHGRALGVTVAADRPDGLAELTDAGIAEEALAVRLLAPAVPWPLSED
                     CLWEGIQALPPGGHLLIGPDGRGHVACGRPLPAPEVPLAEGAPRVREALTGAVRVRTHG
                     QKTLSADLSGGMDSTSVCFLAAGRVDRLLTVVCESGDPAGDDGRWAALAATSLPGAEHT
                     SYRAEDCPRYFTGLLDTDPDLEAPLPSVHTRAMVLDQARRMAAAGSTRHLTGHGGDELF
                     LPTPAYLHDLLRRRPLRALGQVRAGRAVHRWRTGPTVAALLDRTSYADWLGHEVGWNLR
                     NPIRGVNAAPLSGWGPAYRMPAWATSEAVHSVRHTLRQVARARPAPLSPLRGRHLTVHQ
                     IRQGGDLVRRIDRLSARHGVTIEAPFLDDQVVEAALALDYADCLRADRYKPALVEAMRG
                     VVPRRSLGRRSKAEFSADIYAGLRANRRELLELCDGMRLASLGLVDAAALRAVVLSPPP
                     ISLELLPLLNTFACEVWLRSVGTSRPRSRAASEAGR"
     gene            11836..12087
                     /locus_tag="KLI87_RS04440"
                     /old_locus_tag="KLI87_04445"
     CDS             11836..12087
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="KLI87_RS04440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04445"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_156214718.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.5e-20,
                     bitscore: 69.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-12, bitscore: 44.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSGEVTVTDTGAGLVLLNERTGRYWSLNGTARAVLLMLADGST
                     PEEAVESLTLQHPDFADRVASDVEALIESLLEEKVLLP"
     aSDomain        11839..12075
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KLI87_RS04440_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.30E-22"
                     /identifier="RREFam002.1"
                     /label="KLI87_RS04440"
                     /locus_tag="KLI87_RS04440"
                     /protein_end="80"
                     /protein_start="1"
                     /score="69.8"
                     /tool="antismash"
                     /translation="RLSGEVTVTDTGAGLVLLNERTGRYWSLNGTARAVLLMLADGSTP
                     EEAVESLTLQHPDFADRVASDVEALIESLLEEKV"
     gene            12084..12512
                     /locus_tag="KLI87_RS04445"
                     /old_locus_tag="KLI87_04450"
     CDS             12084..12512
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592830.1"
                     /locus_tag="KLI87_RS04445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04450"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_156214717.1"
                     /sec_met_domain="PF13471 (E-value: 1e-25, bitscore: 86.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMPVALEPRPRVSRRRRAAALAAVSAATLLERLPPRRLRRVLEA
                     ARRGAGPATAAQALAAREAVVAVSIRCAGQGCLRRSVAVALLCRMGGAWPDWCTGVRVE
                     PFRAHAWVEANGAAIGELDDMHLYHKTMSVPARRRGGR"
     gene            12515..13060
                     /locus_tag="KLI87_RS04450"
                     /old_locus_tag="KLI87_04455"
     CDS             12515..13060
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.5"
                     /locus_tag="KLI87_RS04450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04455"
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_250903613.1"
                     /transl_table=11
                     /translation="MREVFSLAAQSLMAGVFALAAFSKLRGREEFGRFATTVRKLTMRS
                     GPETAAVAGAFAAVEALTAVLIAVPATAPAGLWTAAALLTLFIGVVFRAVRGRVFAECG
                     CFGGSAAMSYPLLGRNALLLTLALAGLAASGDRAAWEGPALRGLALAIGLAAASALLRS
                     FDRAVTLVLGRVHARTRT"
     gene            13057..14013
                     /locus_tag="KLI87_RS04455"
                     /old_locus_tag="KLI87_04460"
     CDS             13057..14013
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017534155.1"
                     /locus_tag="KLI87_RS04455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_214615923.1"
                     /transl_table=11
                     /translation="MTAPAAPSIEVRGVTKRFGRVTALDDVDLTVPKGAVHGLLGHNGA
                     GKSTLVGILATLLRPTGGSVRVAGLDVLERPAQVRRRIAVTGQQTTLDLTMSGRDNLYM
                     TARLLGAGRRAARARTGRLLEAFELTAAADRPARAYSGGMRRRLDLAMTLVRRSEVVFL
                     DEPGTGLDPASRLATWDMVRRLTATGTTVVLTTQHLEEADRLADAVTVLADGRVVATGS
                     PEELKRRIGRRSATVHLATAADTLAADHALAGAGLHPECDHPRRALTVTLNRDRDLTAV
                     VRALDAAAIEPTRLTLAEPGLDQVYLALTGHRRTEAP"
     gene            14010..14852
                     /locus_tag="KLI87_RS04460"
                     /old_locus_tag="KLI87_04465"
     CDS             14010..14852
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629987.1"
                     /locus_tag="KLI87_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04465"
                     /product="ABC transporter permease"
                     /protein_id="WP_250903478.1"
                     /transl_table=11
                     /translation="MTVRAPLTTDRPHEPLTGSGDWHGAPTTTQIGILTARSMRALVLN
                     RRLLIIGLLESLVMLVAFGQVFSGLAYAPGFPAGVRYVDFLLPALLLTTTLQSGIQAGI
                     GVTDDAQSGILDRLRSMPVWPGSILIARSLAGLARGALRLAVLLALARVLFGYDPAGGV
                     RGVLAAAGLSLALSWSLGWLFIALACWIDQTEALHATAGLVMFPLMYASNAFVPVGGLP
                     GWLRRIARYNPVSHGIDSARDLCLTGTTGPGVLNAVLAGLLIAVLAAAAAVRGLSRAR"
     gene            15095..16249
                     /locus_tag="KLI87_RS04465"
                     /old_locus_tag="KLI87_04470"
     CDS             15095..16249
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) Chlor_Efflux_Pump"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891893.1"
                     /locus_tag="KLI87_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04470"
                     /product="Cmx/CmrA family chloramphenicol efflux MFS
                     transporter"
                     /protein_id="WP_214615924.1"
                     /transl_table=11
                     /translation="MPLPLYLLALAVFAMGTSEFMLAGLVPDIAGSLGVSAGTAGTLTS
                     AFAIGMCAGAPLMAGLIRDRPGRTSLAGFVLVFAAAHVAGALTTDFALLFATRIVAALA
                     NAGFLAVALTTASALVAPERKGRALAVLLAGTTVATIAGVPGGTVLGALFGWRAAFWAV
                     AALCLPALAGIVAGVPGRPVQGEGADGRALRPELARLKSPRLVLVMLLGALVNAGTFCG
                     FTFLALIVADERWVPVVLVLFGAGSFAGVGVAGRLSDRRPGLVVAVGGPPLLIGWPALA
                     LLADQRAVLLVLVFVLGALSFALGSTLIARVLYEAAGAPRMAGSYATAALNLGAVVGPL
                     IGAAALGGGTAGPFWASGALVATALVVALPSRAAIAGEASTPAR"
     gene            16375..16560
                     /locus_tag="KLI87_RS04470"
                     /old_locus_tag="KLI87_04475"
     CDS             16375..16560
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLI87_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLI87_04475"
                     /product="hypothetical protein"
                     /protein_id="WP_156214713.1"
                     /transl_table=11
                     /translation="MVVGTVVALIVAASLIPAGPSTPLPRPQCERGGGVVAPGPSMTGL
                     VCYGGIHNFAPAEFWF"
     misc_feature    complement(16400..16420)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     misc_feature    16507..16509
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16673..17848
                     /locus_tag="KLI87_RS04475"
                     /old_locus_tag="KLI87_04480"
     CDS             16673..17848
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.5"
                     /locus_tag="KLI87_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04480"
                     /product="serine hydrolase"
                     /protein_id="WP_214615925.1"
                     /transl_table=11
                     /translation="MTSTNESKRGRGVRRTVAVVAAGAALGGVAAAPAQAAAPTQGTRG
                     CGDHAATRRVLDRLTGVHKLTGAAVRVDDPRCGTWTAASGVADRRTGRPMTADTRTRVG
                     SITKSFTATTVLALAGEGRIALDAPVDRYLPGLIDKNGYDGREITVRSLLRHTSGLPDH
                     MDAFASTEEWRFRHFEPEELVRLSLSMPAPEEEWSYSTTNYVIAGLLIEKVTGHRAEEE
                     IQRRIIAPLGLRETYWPGDDVRLRGSRLRGYVRQEEGGTLRWADYTEMNTTVAWTGGAL
                     VSSPRDVNAFYGALLGGRLLPPGLLAEMKRTVELNPDQVWPDARYGLGLIGTPLRCGGT
                     WLGHAGDIDGFTSMAGVAPSGRRVALAFNENPSSQEAFDDELNLVQTALCE"
     gene            17863..19404
                     /locus_tag="KLI87_RS04480"
                     /old_locus_tag="KLI87_04485"
     CDS             17863..19404
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (105-268). E-value:
                     1.4e-08. Score: 26.6. Matches aSDomain:
                     nrpspksdomains_KLI87_RS04480_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891030.1"
                     /locus_tag="KLI87_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04485"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_156214711.1"
                     /sec_met_domain="PF00561 (E-value: 2.2e-11, bitscore: 40.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINARRAAVLVVGAAAAGAAAMSAVSAPSATAHTKNDLGRFYQQR
                     LDWKACTQGPDDEVGKELDKAGARCADVTVPLDYADPGGRTITVGISRLKASGDEPRLG
                     MMLLNGGGPGAAIDLPPYMRELMGKAGPRYDLVGMDPRALGRSAGVDCGWPSATWIKGP
                     GATREAFDASVRYAKDLADRCARTDTSVLPHISTRNIARDMDVIRGALGERKMSYNGAS
                     YGTYLGSVYATMFPGRLDRVLLDSSQDPYSWGPRLLAGTENANEKALADWAGWAAERDD
                     EYGLGKTRDEVVGLVHRILAASARAPLAIGQYKLDASMLPVVLVDNLGTDDEPARAGLA
                     ESVRVLRDAAAGRPAKPTPDLADELAYLLTGADSREGSGQAAIICGDVAAPRDPAFYWR
                     DVQAHRGGAPVFGALAHNIGPCAFWPTRPAEAPTKVGADLPALMVAATGDTRTTYERNE
                     TVHRLMRGSRMITLDANVHAPYQRGYPNTCVRERVNDYLLTGRLPARDLTCPPDK"
     aSDomain        18178..18666
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KLI87_RS04480_Abhydrolase_1.1"
                     /evalue="1.40E-08"
                     /label="KLI87_RS04480_Abhydrolase_1.1"
                     /locus_tag="KLI87_RS04480"
                     /protein_end="268"
                     /protein_start="105"
                     /score="26.6"
                     /tool="antismash"
                     /translation="MLLNGGGPGAAIDLPPYMRELMGKAGPRYDLVGMDPRALGRSAGV
                     DCGWPSATWIKGPGATREAFDASVRYAKDLADRCARTDTSVLPHISTRNIARDMDVIRG
                     ALGERKMSYNGASYGTYLGSVYATMFPGRLDRVLLDSSQDPYSWGPRLLAGTENANEKA
                     "
     misc_feature    19585..19605
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            19818..20876
                     /locus_tag="KLI87_RS04485"
                     /old_locus_tag="KLI87_04490"
     CDS             19818..20876
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014977.5"
                     /locus_tag="KLI87_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04490"
                     /product="S1 family peptidase"
                     /protein_id="WP_156214710.1"
                     /transl_table=11
                     /translation="MNRGEHLKGVVPPLLGAAALIAVSVSAIAPASAQPQEAGTVRLAQ
                     LPHNALADQLTGRLGGRQAGTYLDGAGNLVVNVTSEAAAQQVRASGAKARVVKHGIAPL
                     TASMTKLDRLAGTDGTVGLAWGVDVISNAVVISVPQGDNDAATKAFVKRARALGDTVQI
                     KRVAAAPRLTLGPGEAILTGGSRCSVSAIGASGGTEYVVTAGHCTNIGSTWTTSGGQTV
                     GTRQASSFPGNDYGTIRKTGSVSLTNAQLTQVGKPQAGTQIQKKGSTTGTTSGTIRGYN
                     RTVNYQEGAVSGLIETTACVQPGDSGGSLQSGSTAIGITSGGTTGSCRSGFQSYFQPLD
                     EALQSQGLTLKR"
     gene            complement(20931..21596)
                     /locus_tag="KLI87_RS04490"
                     /old_locus_tag="KLI87_04495"
     CDS             complement(20931..21596)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KLI87_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KLI87_04495"
                     /product="hypothetical protein"
                     /protein_id="WP_214615926.1"
                     /transl_table=11
                     /translation="MGATTLVTVVLFVLAAAGGAFAAQRLRAKSRHPGVAELARGKVCL
                     FCLSPVPVDGRFATLTESKARESLGAAPPEGASFTGPQGEKQFLTHIECLRDAQEEVCM
                     FCLRGILPGEEMAFIERPYARDVLGEEPVERAAGVDPGGKPCFFGHADCTREATKALCM
                     FCLTEMKAGDISIGFEKPRARELLGAEPSPRSETTEPGGNGCHVAHAECARAAGADIG"
     gene            complement(21661..22266)
                     /locus_tag="KLI87_RS04495"
                     /old_locus_tag="KLI87_04500"
     CDS             complement(21661..22266)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025631.5"
                     /locus_tag="KLI87_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KLI87_04500"
                     /product="DUF4360 domain-containing protein"
                     /protein_id="WP_173390637.1"
                     /transl_table=11
                     /translation="MKKTKNAALVAVGAAALPLLTAFPASAVPEPSAKAQVVRSACPGE
                     VSVSEDGGRVNVKIKNFKASVGGDVNPKEAQKSCSFSISIRIPQGFTGAVASTDTRLAA
                     DLDPGVVGELTQSYRWRGSPGSDVSMHAVAGHKGNLQFTDMVPTAQLKYARCDAPEFLD
                     LETRIRVKSSDPSEEGWLSLDSPGGGMTYSFAYKVCNR"
     misc_feature    complement(22281..22301)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.97"
                     /tool="antismash"
     misc_feature    complement(22376..22390)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 ggagcacctc atggccatga ccagagtccg tcccagcggc ttgttcaaga cgcgcgggcg
       61 ccccaccgcc gcgccgatcc gcccccgcga ctccgccgtc atcgactggg ccgcctacat
      121 cgacgggcac cgcgcctcca cggcgaccgt cgaggacgcc gtgcgcctca tccgcgacgg
      181 ccgcctcacc gccgacggcg actccgcggg cttcgtctgg gtcgggctcc acgagccgtc
      241 cgcgaccgag ctgaccgagc tggccgaggt cttcggcctg cacccgctcg ccgtcgagga
      301 cgcgatccac gcccaccagc ggcccaagct ggagcgctat gacgacgtgc acttcgtcgt
      361 gatgaagacc gtcggctacg tcgcgagcgg gccgggcggc gcggaggtcg tcgagaccgg
      421 cgagatcatg atcttctgcg ggccggactt cgtcgtcacc gtccggcacg gcgcgcacgg
      481 ggccctcggg cccgtccgcg agcagttgga gcgcgacccg gcccgcctcg gcaagggccc
      541 ggcggccgtc ctgcacgccg tcgccgaccg cgtggtggac ggctacgtct gcgtcgccga
      601 cgccgtccag gaggacatcg acgaggtcga ggaggccgtc ttctcccccg agcgcaccga
      661 cgagtcccgc cgcatctacc gcctcaagcg cgaggtcatc cagctcaagc gcgccgtcgg
      721 cccgctcgcc ggcccgctgc gcaacctgtc gggccgccgc ttcgtgcccg ccgagatcaa
      781 ggagtacctc cgggacgtcg aggaccacct cacccgcgtc cgcgagcagg tcgagtccta
      841 cgacgagctg ctgaacccca tactccaggc ccacatgacc caggtgaccg tcgccgacaa
      901 ccaggacatg cgcaagatct ccgcctgggg cgcgatcttc atggtcccga cggccatcgc
      961 cggggtctac gggatgaact tcgacttcat gcccgagacg cagtggcgct acggctaccc
     1021 gctgatcctc gccgtcatcg gcctggcctg tctctccctc taccgaggct tccgccgcaa
     1081 cggctggctg tgactattca agtcccggcc caaggcactc gcctggcggc tcgtaccttg
     1141 accgtgcctt ggcgggcgcg gcatcgcttc gcgatcttcc cggtggggct cgcctccggc
     1201 ttcgccccac cgctcagcca cgcgcccgcg cggtggctga ggccacttcg cagcgcgctc
     1261 taggcgcgga cggcgagagc caggtccggg tagtcggtga cgagcgcgtc cacgccgtat
     1321 ttggtcaggc gcgacatgtc ctcgggctcg ttgaccgtcc acgcgatgac ggggagcgcg
     1381 gcggcgtggg cgtcatcgac cagggccggg gtgatcagcg tgtgttcggg cgacagcgcg
     1441 gtcgcgccga tcgccgtggc ggcggcgacc gggtcgtccg gcgcgagtcc ggcgagccac
     1501 gcggtgcccg ggacgagcgt cttgcgctcg accagtgcca cgcggccgag cgccgggtgg
     1561 cggtgggcct ccgcgaggac gcgccagtcg aaggccagca gccggctcct acgggtcacc
     1621 cccgccccct ccaacacgga cgcgacggcc gacacgaaca gggcgatgtc ttcgtcgggc
     1681 caggtggggt cggtcttcag ctccaccgac agccgcacct cggacggcgc cagcagcgcg
     1741 cacgtctcgg cgagcgtcgg gaccggggtg cccggcagcg ggagctgcgt cgccgtgaac
     1801 gcgtcgtcgc gtcgccggac gcccgcgtcc acggtcttga gctgctccag cgtgaggtcc
     1861 ccgaccgcct tgccgacata ggggaacgcc gggtcaccgg gacgcgccgg cctcgtgtcg
     1921 gacagggtca ccggcgagag gacctggtcg tggacgagga cgaccgcgcc gtccgaggtg
     1981 aggccgacgt cgagctcgac ggcgtccacg cccagcgcga gcgcgtgggc gaagccgggg
     2041 agggtgttct ccggacgaag cccccgcgcc ccccggtggc cgtggacctc gacggttcgc
     2101 gtcacgtcac cgcacgctag cgccggcgcc tcgggccctg gtggacatgg ggtaaaggcg
     2161 cgaggtcaga tgaggggacg cagcgacagc gtctgctcgc ggccgggccc gacgccgatc
     2221 gcggagatct gggcgcccga catctcctcc agcgtccgga cgtaggcctg cgcgttcttc
     2281 ggcaggtcgt cgaacgtctt cgcggccgtg atgtcctcct tccatccgtc caggtgctcc
     2341 aggacgggct tggcgtggtg gaagtcggtc tgcgtggtcg gcatctcctc gacccgctcg
     2401 ccgtcgatct cgtaggcgac gcagaccggg acgcgctcca ggccggacag gacgtccagc
     2461 ttggtgagga agtagtcggt gatcccgttg acccgggtgg cgtagcgggc gatcaccgcg
     2521 tcgaaccagc cgcagcggcg gtcgcggccg gtggtgacgc cgtactcgcc gccggtcgtg
     2581 cgcaggaact cgccctgctc gtccagcagt tcggtgggga aggggccgga gccgacgcgg
     2641 gtcgtgtagg ccttcaggat cccgatcacg cggctgatcc gggtggggcc gatgcccgag
     2701 cccgcgcacg ccccgcccgc cgtcgggctg gaggaggtga cgaacggata ggtgccgtgg
     2761 tcgaggtcga gcagggtgcc ctgggcgccc tccagcagga cgaccttgtc gtcctccagg
     2821 gccttgttca gcacgagcga ggtgtcggcg acgaacggcc gcagccgctc cccgtaggcc
     2881 aggtactcct ggacgatcgg gcccgtctcg atccggcgcc ggttgtagac cttcgtcagg
     2941 acctggttct tctcgcgcag cgacaggtcg agcttctggt tcaggatgtt cgggtcgaac
     3001 aggtcctgga cgcggatgcc catccggttg atcttgtcgg cgtaggcggg gccgatgccg
     3061 cgcccggtcg tgccgatcct ggccttgccg aggtagcgct cggtgacctt gtccagggcc
     3121 cggtggtggg gcatgatcag gtgcgcgttc cccgagatca gcagccgttc gcaggtgatc
     3181 ccgcggtccc gcagcccgtc gatctcctgg agcagcacgg ccgggtcgat cacgacgccg
     3241 ttgccgatca cggggaccac gtcgggggag agcaccccgg acggcagcag gtgcagcgcg
     3301 tagctcttgt cgccgatgac caccgtgtgg ccggcgttgt tgccaccctg gtagcggacg
     3361 acgtagtcga cgtccccgcc cagcaagtcg gtggccttgc ccttgccctc atctccccat
     3421 tgggctccga caagaacgat ggccggcatg ccgctgttcc cttcccacga cgaaggcccc
     3481 ggtcgccgca agagcgaagg ggcctcttgc gatcaaagcg tacccgtacc tggacctaga
     3541 ggaaaacgca cgccgtccgg gggtgggccc cgcgaaaacg atcagcggtg ctgatcagcc
     3601 gccgaggacg tcggccgccg tggggctgct gtcgctcagg aacgtgcggc agcgctcggc
     3661 ctcgtcgtcc tcgccgatcg cggcggcggc gcggccgagg gcgtgcaggg cgcgcaggaa
     3721 gccccggttg ggctcgtgct cccacgggac gggcccctgc ccgcgccagc cggcgcggcg
     3781 gagctggtcg aggccccggt ggtagccggt gcgcgcgaag gcgtaggagt cgatcacacc
     3841 gcccctggcg aaggcgcggt cggccagttc ggcccaggcc cccgggtagt ccgggtggcg
     3901 cgcggccacc tcgaacgggt cgacgtcgtt cgccagggcc tcccgggcct cggcgttgtc
     3961 cggcagttcg gtcggaggca cgccgccgag caggttgtgg gtcatcgggt catcgtaggt
     4021 cggcgcgcct cgccacgccc accccggggc gccgactgcc gcggccgcgg agccgcgagc
     4081 cctaggcccg gacgggcagc ggcagccgga aatgtgcggc gccgtccgca ttgctcgcgt
     4141 gtgcggcggg ccatccgtgc cggacgaacc ggagcgcgtc ccggttgccg aggatgacgt
     4201 cggcctcgaa ctcggtgatg ccgcgccgcg cggccagcgg cgcgaggcag cggaccagcg
     4261 cgctgccgac gccccggcgc tgccaggggt cggtgacgag gacggcgagg tcggcggacc
     4321 agggccggcg ccggtcccgg ctgtactcgg cgacgcccgc gatctcgtcc ccgtccagtg
     4381 cgaccagggc ctcccggtcc cagtggtcga gccgctccag caggcggacg tagtgctcgg
     4441 ggatgtgcgg cgtgccggag aagaaccgcg tgtagaggct ggtcttggag agccgttccg
     4501 acatccggcg cagccggggc ccgtcggtga tcccgtacgg gcggatccgt acgtcctcca
     4561 gcgcgggcgg ggcgaggtgg gcggtcggcc gcacaccgag tttcgtcatg caacccattg
     4621 gaccgcattg agttgcgtga agcaactggc gattttcagc ggcccggacc cggacggggt
     4681 tccacgtcgg ccggtcccag tgaggcgccg caggcgtcgc aggtgaagtt cgccgtgagc
     4741 gtccccgggc agccgcgatg gccgatgagc gtcggcgggc cgtccggggc gtagtggcgg
     4801 tccccccacg ccatcagcga catcatcgtc ggccagagct cgacgccctt gcgggtgagg
     4861 cggtactcga agcgctcggg gcggtcctgg taggggacgc ggcgcaggat gccctcgtcg
     4921 cagagccgcg acaggcggtc ggtgaggacg ttgcgggcca cgcccagcac gtcctggaag
     4981 tcgtcgaacc gccggacgcc ctcgaacgcc gcgcggacca ccagcatcgt ccagcggtcg
     5041 cccacgatct ccagcgagcg ggcgatcgag cagttctgtg actcataggt acggggcagt
     5101 gccacgctgc gaggctaccc gctggaggag aaggcggcgg ggcccggccg ccatcggccc
     5161 ggaccccgcc ggaacgtcac ttcagccgct tgcccgccga cagcaggtgc tcggacgcct
     5221 cgacgacccg ggccgccatc gccgcctcgg ccgccttgcc ccacgagcgc gggtcgtact
     5281 gcttcttgtt gccgacctcg ccgtccacct tcaggacgcc gtcgtagttg cggagcatgt
     5341 ggtcggccac cgggcgcgtg aacgcgtact gggtgtcggt gtcgacgttc atcttcacga
     5401 cgccgtagga cacggcctcc cggatctcct ccagtgtgga gccggagccg ccgtggaaga
     5461 ccaggtcgaa cggcttctcc ttgccgtact tctcgccgac cgcgtcctgg atgcccttga
     5521 gcacctcggg acggagcttg accgagcccg gcttgtagac gccgtgcacg ttcccgaacg
     5581 tcgcggcgag gatgtagcgg ccgcgctcgc cgacgccgac ggcctcggcg gtcgcgaggg
     5641 cgtcgcccgg cgtcgtgtag agcttctcgt tgatctcgtt ggcgacgccg tcctcctcgc
     5701 cgccgacgac gccgatctcc atctccatga tgatccgcgc cttcgcgcac tggtcgagca
     5761 gttcggcggc gatctggagg ttctcctcca gcggcacggc cgacccgtcc cacatgtgcg
     5821 actggaacag cggctcctcg ccgcgcgcca cccgctcctg cgagatcttg accagcgggc
     5881 gcatgaagcc gtccagcttg tccttcgggc agtggtcggt gtgcagcgcg atgttcaccg
     5941 ggtacttggc ggcgaccacg cgggcgtact cggcgagggc gctcgcgccg gtgaccatgt
     6001 ccttcaccgt ggcgcccgag aggtactccg ctccccccgt ggacacctgg acgatcccgt
     6061 cgctctccgc ctcggcgaag ccgcgcagcg cggcgttcag cgtctggctg gacgtcacgt
     6121 tgatggcggg ataggcgaag ccgtcctgct tcgcacggtc gagcatctcc gcgtagacct
     6181 cgggcgttgc gatgggcatt gtcagcgtcc tttcttacgc agggtgccgc cgggcatccg
     6241 gccgggcggt agctcccgtc ccccgcctac ccagccgatt cgcctggtca cgcggttccg
     6301 ggcagcgcgt tccgtccacg gtcagtatct cgtcggggcg ctcgcccact ccagaggggc
     6361 cccgcgaggt ggcacaagta tcccggattc cggcgtccgg tcgagggctt tggggcggtg
     6421 cgtccggccc ggcgctccgg cgccgatgag gctccatgcc cccggaacag gccggtttcg
     6481 cgcgtactaa gagcgccggg acgggtacgc tcgcaatgtg gatctcacga cccttcccct
     6541 ggacatcacc gagtacctgc atccgaccgc ctggttgcag ctcttcggca cgtttgcgac
     6601 gatcggcgtc ctcgccatca tcttcgcgga gacagggctg ctgatcggct gcatcctgcc
     6661 gggcgactcg ctgctgttca cggccgggat cctcacggcg gtctccaccg tcaacggcca
     6721 ggagttccag tcgctgtcgc tgccctggct gctgatcggc ggcccgctgg cggcgatcgc
     6781 cggggcccag ctcgggcact ggctcggcgc ccgctacggc cgcaagctct tcgaacggcc
     6841 cgactccaag atcttccggc aggagtgggt ggagaaggcc gagtactact tcaaccggtt
     6901 cggccccgcg aaggcggtcg tgctggcccg gttcatcccc atcgtccgga cgttcctgaa
     6961 cccgctcgcc gggatgctcg gcatggacag ccgcaagttc ctcatctgga acgtcgtcgg
     7021 cggcgtcatc tggaccgaca cgttgttcct gctggggcac ttcctcggct ccgaggtgcc
     7081 cgacgtcgag cgctacatcc tgccgggcgt cgccgtgatc ctcgtgctgt cggtcatccc
     7141 gatcatccgc gaggtcatga aggggcggcg ggcctcacgc gggggcggca agcactcgcg
     7201 tccgaagaat aatggccccg aagagtctcg tccgtcgctc agcggtgaca gttatcgcta
     7261 acctccccat gtgggacgtc atcggtcgga ccctcgtggt ctcgcgcgca tactgatcgc
     7321 ggtagtagcc gtggtcgccg ctttgggtct cctcgtggcc ggcggcctct ccctagtgaa
     7381 cgcggtctcg ggcgactccg acaaccacga tcccgcgacc gtctccccgt cccccgggga
     7441 cggcgggggc cagaacaggt ccgccccgag ccgcagcccg tcctcctcgg cgtcgggcgc
     7501 gctccccctg gtcatccggg tgaccggccc ggcgaccaac gtcgtcgtcc gcgtcgccac
     7561 caccggcgag atcctcaccc aggccctgct gtccaccggt gacacccgca agtacgagca
     7621 gacccccctc caggtcgtcg ccacgaacgg cggcgccctg gaagtgatga tctacggcag
     7681 gaagtggccc cccaagccgt ccggctcgcg gggccagtgg ttcgtctccg ccaagaagtg
     7741 acctgtggcg gtcaggacac ctcccacgcc tggtcctggc tgacgacgca ctcccagttc
     7801 aggaccccgc ccccgggggc gaagttgccg gcgacgacgg tgaggcaggt gccgttgatc
     7861 ccgctcgcca gcttgtcgcc gacgaagtgc cactgctggc cccgcgtgtt gttgcagtcg
     7921 tagatgttgg tggcggcccc gttgcgcccg ttcccggtcc ggacgtccag gcaccggtgg
     7981 ccggggaggc cggtcctgat catgccgccg tcgagcgtcc accgctggtt gtcgcggccg
     8041 gtgcaggtgt agagggtgac cagggcgccg ttgccggagt tgtcgtccgc gacctcaagg
     8101 cacaggtcct tggccgccac aggcttgatc aggacgccgg cgaggtcccg ccgggtctcc
     8161 ggacggggcg agggcgccgc cgaggccgac gagccggccc acagcccgcc ggccatgacg
     8221 acgaccggca gcagggcgaa catcgaggat ccgcgcatcg tgctctccgt ttcgaccgtg
     8281 gggcccgccc gaccggcgtt ccccgccgcc ccaacggtcg cgccgccgcc ggtcgggcgg
     8341 ccatccccag atcctgggat atgcaacgcg tacttgttcg ctttcaatgc gtggccgata
     8401 ctgggccgcg tgagcgctgg acggagcgca cccgccgccc tggccggcgc ggcgacggag
     8461 atcggctcgg ccgccgagtt gggggcggtg gtctcccggt gggtcggacg cgcggtgccg
     8521 catgagggct acatgctcgc cgcggtcgac cccgtcaccg gcgcggggtg cttcctggcg
     8581 cgcgagcacg gctactcgcc ggcggccgcg cggcggctga ccctgggcga ccgccgggaa
     8641 cgcgaccacc cgttcccctt cgagcgcctg gtggagggcc cgtgccacgt gggcgtgctc
     8701 aacaccgacg ccccgggacg ccgccgcaac gccgcgatgc gcgcggtgat gaccgacctc
     8761 ggcgtgggca gcgagctgcg cctggcgctg gtcgacggcg ggacgacctg gggcggcctg
     8821 gtgctgctcc ggccccgggg cgcccgcccc ttctcgccgg acgaggcgtc ccgcgcccag
     8881 cgtctggccc gcgacatcgt cgccgcgctg cggcgctacg cgacgggcgc gcctccggaa
     8941 ccgaacaggc tcgacgcgcc accgggggtg ctggtcatcg acccggacga gacggtcacg
     9001 gccgccaccc cgtcggcgcg cgcctggatc cgcgaactgg agacgcttcc tcccgccgcg
     9061 ctggccgcgc cggacctgcc gttggagagc accatctggc acctcaccca ggcggcccgc
     9121 tccgacggct cggggcgggc cacgctgacg cgcgtgccga cgcgacgcgg ctgggtcgcc
     9181 atccaggccc aaccgatgcc cacgggcgcg gtcgccgtga cgatccaggc ggccgccggt
     9241 aaggaactgc tcccggcggt ggccttctgg cggggcctca ccccgagaga gcacatggtc
     9301 gtcgaccaca tgctcaaagg gctatcgagc aaacaaatcg cccgccattt gcgcctctcg
     9361 ccgcacacgg tcaatgacca tctgaaatcc atctaccgca aaaccggtgt ctccacccgc
     9421 gaagaactcc tggcgcgctt cctcgactga cccccgagca gggcggtact cctgccgccg
     9481 gtggggtggc gctggcggtg ccgccacacc ccggccattc ccggccacat cctgtgaccc
     9541 gcgcagcggc tgacctgcaa gggcttgcgg ggcggtggcg aggtctccct acccgaactc
     9601 ctattcacta ctgtccgtag tgatatatac accctgagcg atcgtcgggt tctatgttgc
     9661 tcaccgctga ccgcccactt caggagagga ggtgaacccg acatgagcat ggcttacgag
     9721 ccgcccgcct tcgtggtgat cggcgacctg cgcgaggtca ccctcggaga taaaacctgg
     9781 ggattcgacc gcatcaacca gtgcgccttc tacaactgcg tgcagtagcc cgctcgcgat
     9841 tccccggccg gcacccgcgc ctggggaagg gccgtgccgg tcgtcaaaga ccggcacggc
     9901 cggcgcccac ctttcgaaat gcccggcatc gaacaccgcc gggcccggct ttcgcgcggg
     9961 acgcgttcac ggtgagccgt cccgctcgct gggagaaggc atgcggttct tcgtggttcc
    10021 cgacaattcc gagggtgccc tgctcgcggc gtccctgcac acccggtggc ccgacctgcg
    10081 ggtgctgccg cacgactcgg gacgtccgtg ggtcgtgggc cggtggcagg acgaggaggt
    10141 ccgctgggcc gcggcgggcg cccggcggat cgcgctgctg gggcgggtcc aggcgagcgc
    10201 gccatggctg accgagtaca tcgccgggca gcgcgacctc ggagccctgg cggacctgcg
    10261 ccgcgagctg ccgggcagct accacacggc cgccgtgatg gaccgggtcg tgttcgtcca
    10321 gggggacctc tcgacggtgc gggaggtctt ccacggccgg gcgctggggg tgacggtcgc
    10381 ggccgatcgc cccgacgggc tcgccgagct gacggacgcg gggatcgccg aggaggcgct
    10441 ggccgtcagg ctgctggcgc ccgccgtgcc gtggccgctg agcgaggact gcctgtggga
    10501 ggggatccag gcgcttcccc ccggcggcca cctgctgatc gggcccgacg gccgcggcca
    10561 cgtggcctgc ggccgacccc tgccggcgcc cgaggtcccg ctcgccgagg gcgccccccg
    10621 ggtgcgggag gcgctgaccg gggcggtgcg ggtccggacg cacggccaga agacgctgag
    10681 cgccgacctg tccggcggga tggactcgac cagcgtgtgc ttcctggcgg ccggccgggt
    10741 cgaccggctg ctgacggtcg tctgcgagtc cggcgatccg gccggcgacg acggccgctg
    10801 ggccgccctg gccgcgacgt ccctgcccgg cgccgagcac acgtcctacc gggcggagga
    10861 ctgcccgcgc tacttcaccg ggctgctgga caccgatccc gatctggagg cgccgctccc
    10921 gtccgtccac acgcgggcga tggtgctgga ccaggcgcgc cggatggcgg cggccggctc
    10981 gacccgccat ctgaccggcc acggcggcga cgagctgttc ctccccaccc ccgcctacct
    11041 gcacgacctg ctgcgccgcc ggccgctgcg ggcgctcggg caggtgcgcg ccggacgggc
    11101 ggtgcaccgc tggaggaccg gtcccaccgt cgccgcgctg ctggaccgca cctcctatgc
    11161 cgactggctg gggcacgagg tcggctggaa cctgcggaac ccgatccgcg gcgtcaacgc
    11221 cgccccgctg tcggggtggg ggcccgccta ccggatgccc gcctgggcca cctcggaggc
    11281 ggtgcactcg gtccgccata cgctgcggca ggtcgcgcgg gcacgcccgg cgccgctctc
    11341 gccgctgcgc gggcggcacc tgaccgtgca ccagatccgc cagggcggcg accttgtgcg
    11401 ccggatcgac cggctgtcgg cccgccacgg cgtcaccatc gaagcgccct tcctggacga
    11461 ccaggtggtc gaggcggcgc tggccctgga ctacgccgac tgcctgcggg ccgaccggta
    11521 caagcccgcg ctggtcgagg cgatgcgcgg cgtcgtcccg cgccgcagcc tcgggcggcg
    11581 ctccaaggcg gagttcagcg ccgacatcta cgcgggcctg cgcgcgaacc gccgtgaact
    11641 gctggagctg tgcgacggga tgcggctggc ctcgctcggc ctggtcgacg ccgccgcgct
    11701 gcgcgccgtc gtgctgagcc cgccgccgat ctcgctggaa ctgctgccgc tgctgaacac
    11761 cttcgcgtgc gaggtgtggc tgcgctcggt cggcacgagc cggccgcgct cgcgcgccgc
    11821 gtcggaggcg ggccgatgag gctgtccggc gaggtgaccg tcaccgacac cggcgccggc
    11881 ctggtgctgc tcaacgagcg gaccggacgc tactggtcgc tcaacgggac ggcccgcgcc
    11941 gtgctgctca tgctcgcgga cgggtccacg cccgaagagg cggtggagag cctgacgctc
    12001 cagcaccccg acttcgccga ccgggtcgcc tcggacgtgg aggccctcat cgaatcgctc
    12061 ctggaggaga aggtgctgct cccatgacga tgcccgtggc cctcgaaccg cgtccgcggg
    12121 tctcccgccg gcgccgggcc gccgccctcg cggccgtctc cgccgcgacg ctgctggagc
    12181 ggctgccgcc gcggcggctg cggcgcgtcc tcgaagcggc gcgccggggc gccggtccgg
    12241 ccaccgccgc gcaggcgctg gccgcgcgcg aggcggtcgt ggcggtcagc atccggtgcg
    12301 ccgggcaggg ctgcctgcgg cggtcggtcg ccgtcgcgct gctgtgccgg atgggcgggg
    12361 cctggccgga ctggtgcacc ggcgtccgcg tcgagccctt ccgcgcgcac gcgtgggtcg
    12421 aggcgaacgg cgccgcgatc ggggagctgg acgacatgca cctctaccac aagacgatgt
    12481 cggtgcccgc ccggcgccgg ggcgggcggt gacgatgcgc gaggtgttct cgctggcggc
    12541 ccagagcctg atggccgggg tcttcgcgct cgccgcgttc agcaagctgc ggggccggga
    12601 ggagttcggc cggttcgcca ccaccgtccg caagctgacg atgcgctcgg gcccggagac
    12661 cgccgcggtc gccggggcgt tcgcggccgt ggaggccctg accgccgtgc tgatcgccgt
    12721 gcccgccacc gcccccgcgg gcctgtggac ggcggcggcg ctcctcacgc tgttcatcgg
    12781 ggtggtcttc cgggccgtcc ggggcagggt gttcgccgag tgcgggtgct tcggcggcag
    12841 cgcggccatg agctaccccc tgctggggcg caacgccctg ctcctgacgc tcgcgctggc
    12901 gggcctggcc gcgagcgggg accgtgccgc ctgggagggg cccgccctcc gcggcctcgc
    12961 gctcgcgatc ggcctggccg ccgcgtcggc gctgctgcgc tccttcgacc gcgccgtcac
    13021 cctcgtcctc ggacgggtcc acgccaggac ccggacgtga ccgccccggc cgcgccgtcg
    13081 atcgaggtcc gcggggtgac caagcgcttc ggccgcgtga ccgcgctgga cgacgtcgac
    13141 ctcaccgttc ccaagggggc cgtccatggc ctgctgggcc acaacggcgc ggggaagagc
    13201 accctggtcg gcatcctggc gacgctgctg cgccccaccg ggggcagcgt ccgcgtcgcg
    13261 ggcctcgacg tgctcgaacg tcccgcccag gtccgccgcc gcatcgccgt caccggccag
    13321 cagacgacgc tggacctcac gatgtcgggc cgcgacaacc tgtacatgac cgcgcggctg
    13381 ctgggcgccg ggcgccgcgc cgcccgcgcc cggaccggcc ggctcctgga ggcgttcgag
    13441 ctgaccgccg ccgccgaccg tcccgcccgc gcctactccg gcgggatgcg gcggcgcctc
    13501 gacctcgcca tgaccctcgt ccggcgcagc gaggtcgtct tcctggacga gcccggcacc
    13561 ggcctggacc cggccagccg cctcgccacc tgggacatgg tgcggcggct caccgccacc
    13621 ggcaccacgg tcgtgctgac cacccagcac ctggaggagg cggaccgact cgcggacgcg
    13681 gtcaccgtcc tcgccgacgg ccgggtggtc gccaccggat cgcccgagga gctcaagcgc
    13741 cgcatcggcc gccgcagcgc gaccgtccac ctggccacgg cggccgacac gctcgccgcc
    13801 gaccacgccc tggccggcgc gggactgcac cccgagtgcg accacccccg ccgcgcgctg
    13861 accgtcacgc tgaaccgcga ccgcgacctg accgccgtcg tccgcgccct ggacgcggcg
    13921 gcgatcgaac ccacccgcct caccctggcc gaaccggggc tcgaccaggt gtacctggct
    13981 ctgaccggcc accgccgaac ggaggcgcca tgaccgtccg ggcccctctc accaccgacc
    14041 gaccgcacga gccgctcacc ggttccggtg actggcacgg cgcgccgacg accacccaga
    14101 tcgggatact gaccgcccgc tccatgcgcg ccctggtcct gaaccggcgg ctgctgatca
    14161 tcgggctgct cgaatcgctg gtgatgctgg tcgccttcgg ccaggtcttc tccgggctcg
    14221 cctacgcccc cgggttcccc gccggcgtcc gctatgtcga tttcctccta ccggccctgc
    14281 tgctcaccac gacgctccag agcggcatcc aggccgggat cggggtcacc gacgacgccc
    14341 agtcgggcat cctcgaccgc ctccgctcga tgccggtctg gcccggctcg atcctcatcg
    14401 cccgcagcct cgccgggctg gccaggggcg cgctccgcct ggccgtgctg ctggcgctgg
    14461 cccgcgtcct gttcggctac gacccggcgg ggggagtccg gggcgtgctg gccgccgccg
    14521 gcctgtcgct ggcgctgagc tggagcctgg gctggctgtt catcgctttg gcctgctgga
    14581 tcgaccagac cgaggcgctg cacgccaccg cgggcctggt catgttcccg ctgatgtacg
    14641 cctccaacgc gttcgtcccg gtcggcggcc tccccggctg gctccgccgg atcgcccgct
    14701 acaacccggt ctcccacggc atcgactccg cccgcgacct gtgcctgacc ggcaccacgg
    14761 gccccggcgt cctgaacgcg gtcctggccg gcctgctgat cgccgtcctg gccgccgccg
    14821 cggccgtccg gggcctctcc cgcgcccgct gagggcccgg acggccgtca cgagcgaaat
    14881 caacgtgctt cggcgggtgg acgtcaggta ggttgcgggc catgtcgagc cccgaggcat
    14941 ccagggcggg ggctttcggt cacgccgtca gccccccgca ccactgagtt ccaccgttcc
    15001 gccgcgttcg cggccggacg ggttcggcgc gccttcgggg tgctgaccgc ggtgacgaga
    15061 cgtcctcgcc tctcctcacc tcggagccca ctcgatgcct ctgccgctct acctgctcgc
    15121 cctggccgtc ttcgccatgg gcacctcgga attcatgctc gccggtctcg tcccggacat
    15181 cgccggctcc ctcggcgtgt ccgccgggac ggcgggcacc ctcacctccg ccttcgcgat
    15241 cgggatgtgc gccggcgcgc cgctcatggc cgggctcatc cgcgaccggc ccggccggac
    15301 gagcctcgcc gggttcgtcc tggtgttcgc ggcggcgcat gtcgcgggcg ctctcaccac
    15361 ggacttcgcg ctgctgttcg cgacccggat cgtcgcggcg ctcgccaacg cggggttcct
    15421 cgcggtggcg ctgacgaccg cgtccgcgct ggtcgcgccc gagcggaagg gacgggcgct
    15481 cgccgtgctg ctggccggga cgacggtcgc cacgatcgcc ggtgtcccgg gcgggaccgt
    15541 gctcggcgcg ctgttcgggt ggcgggccgc gttctgggcc gtcgccgcgc tctgcctgcc
    15601 cgccctcgcc ggcatcgtcg cgggggttcc cgggcgtccc gtccaggggg agggggccga
    15661 cgggcgggcg ctgcggcccg agctggcgcg gctgaagagt ccgcggttgg tcctggtgat
    15721 gctgctcggg gcgctggtca acgcggggac gttctgcggc ttcaccttcc tcgcgctcat
    15781 cgtggccgac gagcggtggg tgcccgtcgt gctggtgctg ttcggcgccg gttcgttcgc
    15841 gggggtcggc gtcgccggac ggctgtccga tcggcgtccc ggtctcgtcg tcgcggtcgg
    15901 cgggccgccg ctgctcatcg gctggcccgc gctggccctg ctggccgacc agcgggccgt
    15961 cctgctcgtc ctcgtgttcg tgctgggcgc gctgtcgttc gcgctgggca gcacgctgat
    16021 cgcgcgcgtg ctgtacgagg cggcgggggc gccccgcatg gccgggtcgt acgcgacggc
    16081 ggcgctcaac ctcggggccg tggtcgggcc gctgatcggc gccgccgcgc tcggcggcgg
    16141 caccgccggg ccgttctggg cgagcggggc cctcgtcgcg acggcgctgg tcgtcgccct
    16201 gccctcgcgc gctgcgatcg cgggtgaggc gagcacgcct gcgcggtgag ttaagtgctc
    16261 gcggtggcga cacaaaggca tcggtgacga tatgtacgtc agctattacc aagggtagct
    16321 ataggagggc ggtccggggc atacggcaga aagcggcggg cgatgaggcg gttcgtggtc
    16381 gtcggcacgg tggtggccct catcgtcgcc gcgtcgctga tacccgccgg gccctccaca
    16441 cccctgccgc gcccgcaatg cgagcggggc ggcggcgtcg tcgcgccggg gcccagcatg
    16501 accggattag tctgttatgg gggtattcat aacttcgccc ccgccgaatt ctggttctga
    16561 tcggctccgg gagtagggct gtcctcaggg tgcgcaatgc gggtatcccc cggcgaattc
    16621 ggggagatcg ccgcagtgtg ccgcgggtgg gccgacttct aatctcgcgg caatgacctc
    16681 aacgaatgaa tcgaagcggg ggcgcggcgt ccgccggacg gtcgcggtgg tcgccgcggg
    16741 cgccgcgctc ggcggagtgg cggcggcgcc cgcccaggcg gcggccccca cccaggggac
    16801 gcggggctgc ggcgaccacg ccgcgacccg gcgggtgctg gaccgtctca ccggcgtcca
    16861 caagctgacc ggcgcggccg tccgcgtgga cgatccgcgc tgcgggacgt ggacggccgc
    16921 gagcggcgtc gccgaccggc ggaccgggcg ccccatgacc gccgacacgc ggacccgggt
    16981 cggcagcatc accaagtcgt tcaccgccac cacggtgctc gcgctcgcgg gcgaggggcg
    17041 gatcgcgctg gacgcgcccg tcgaccgcta cctgcccggc ctgatcgaca agaacggcta
    17101 cgacgggcgc gagatcacgg tgcggagcct gctgcggcac accagcgggc tgcccgacca
    17161 catggacgcc ttcgcctcca ccgaggaatg gcggttccgg cacttcgagc ccgaggagct
    17221 ggtcaggctg tccctgtcga tgcccgcgcc ggaggaggag tggtcgtact ccaccaccaa
    17281 ctacgtcatc gcgggactcc tcatcgagaa ggtgaccggg caccgcgcgg aggaggagat
    17341 ccagcgccgg atcatcgccc cgctcgggct gcgcgagacg tactggccgg gcgacgacgt
    17401 ccggctcagg ggctcccgcc tgcgcggcta cgtccggcag gaggagggcg gcacgctccg
    17461 ctgggccgac tacacggaga tgaacaccac ggtggcctgg accgggggcg cgctggtctc
    17521 cagcccccgg gacgtgaacg cgttctacgg cgcgctgctc ggcgggcgcc tgctgccccc
    17581 ggggctcctg gcggagatga agcggaccgt cgagctgaac cccgaccagg tctggccgga
    17641 cgcgcggtac gggctcgggc tgatcggcac gccgctgcgc tgcggcggga cctggctcgg
    17701 ccacgccggt gacatcgacg gcttcacctc gatggcgggc gtcgcgccgt ccgggcgccg
    17761 cgtggccctc gccttcaacg agaacccgtc gtcccaggag gcgttcgacg acgagctgaa
    17821 cctcgtccag accgccctgt gcgagtgagg aaggaagcga gcatgatcaa cgcacgaagg
    17881 gcggcggtgc tggtggtcgg cgccgcggcc gccggagcgg cggcgatgtc ggcggtgtcg
    17941 gccccgtccg cgaccgccca caccaagaac gacctcggcc ggttctacca gcagcgcctc
    18001 gactggaagg cgtgcacaca gggcccggac gacgaggtcg gcaaggagct ggacaaggcc
    18061 ggggcccggt gcgcggacgt caccgtcccg ctggactacg ccgatcccgg cggccggacg
    18121 atcacggtcg ggatctcgcg gctgaaggcg tccggcgatg agccgcggct cggcatgatg
    18181 ctgctcaacg gcggcgggcc cggcgcggcc atcgacctgc cgccctacat gcgggagctg
    18241 atggggaagg ccgggccgcg ctacgacctg gtcggcatgg acccccgggc gctcggacgc
    18301 agcgccggtg tcgactgcgg ctggcccagc gccacctgga tcaaggggcc gggcgcgacc
    18361 agggaagcgt tcgacgcctc ggtgcggtac gccaaggacc tcgcggaccg gtgcgcgagg
    18421 accgacacga gcgtgctccc gcacatcagc acccgcaaca tcgcccgcga catggacgtc
    18481 atccggggcg cgctcggcga gaggaagatg tcctacaacg gcgcgtccta cggcacctac
    18541 ctcggctccg tatacgcgac gatgttcccc ggacggctcg accgcgtcct cctggacagc
    18601 tcgcaggacc cctacagctg ggggccgcgc ctgctggcgg gcaccgagaa cgccaacgag
    18661 aaggcgctcg cggactgggc cggatgggcg gccgagcgcg atgacgagta cggcctcggc
    18721 aagacccggg acgaggtcgt cgggctcgtg caccgcatcc tcgcggcgtc cgcccgcgcg
    18781 ccgctcgcga tcggtcagta caagctggac gcctcgatgc tgccggtcgt cctggtcgac
    18841 aacctcggca ccgacgacga accggcccgg gccggtctcg cggagtccgt gcgggtgctg
    18901 cgggacgcgg cggccggacg ccccgccaag cccacgccgg acctcgccga cgaactggcc
    18961 tacctgctga ccggcgccga ttcgcgtgag ggcagcggtc aggccgccat catctgcggc
    19021 gacgtcgccg cgccccgcga ccccgcgttc tactggcgcg acgtccaggc gcaccgcggc
    19081 ggagcgccgg tcttcggggc gctcgcccac aacatcggcc cctgcgcgtt ctggccgacg
    19141 cgtccggcgg aggcgccgac caaggtcggc gcggacctgc ccgcgctgat ggtcgccgcg
    19201 accggcgaca cccgcaccac ctacgagcgc aacgagaccg tccaccggct gatgcgcggc
    19261 agccggatga tcacgctgga cgccaatgtc cacgctccct accagcgcgg atacccgaac
    19321 acctgcgtcc gtgagcgcgt caacgactac ctgctgaccg gccggctccc ggcccgcgac
    19381 ctcacctgcc cgcccgacaa gtaaccgcac acgatccgag gaggcgcggt cccccagggg
    19441 gacgcgcctc ctcgccatgc cgaggcgcac ggggcgtcgt gctgtgaaaa cgcgccgtga
    19501 ccggcggcaa cgcagttcgg cattccagcc tagaaattgc tgcgagtaga cgtcgtgtcg
    19561 cgacgaacca cctggtcgaa gcgcatttcg ccgcgctgtc gatgatgatg gcggccgcag
    19621 gcgcccgcgc cggccgttga aattccagtt gtgccttgaa agctggttca gcggcagcat
    19681 ggcgaagtac tttgcaacca cacgttgcct ttcccgtccg ggcccgcacc agcggattcg
    19741 gcggtcggga acgtgccccg caacccccga gttgccgccg acgctcccca gaggtcggtg
    19801 gcgaaaggcg gacagaagtg aaccgtggag agcacctcaa aggcgtggtc cccccactgc
    19861 tcggcgccgc cgcgttgatc gcggtgtcgg tgtcggcgat cgccccggcc tcggcgcagc
    19921 cgcaggaggc gggtacggtt cggctcgccc aactccccca caacgcgctg gccgaccagc
    19981 tcaccggccg tctcggcggc cggcaggcgg gcacctacct cgacggtgcc gggaacctcg
    20041 tcgtcaacgt gaccagtgag gcggcagcgc agcaggtcag ggcgtcgggc gccaaggccc
    20101 gcgtcgtcaa gcacggcatc gcccccctca ccgcgtcgat gaccaagctc gaccggctcg
    20161 ccgggaccga cgggacggtc ggcctcgcct ggggcgtcga cgtcatctcc aacgccgtcg
    20221 tcatcagcgt cccgcagggc gacaacgacg ccgcgaccaa ggcgttcgtg aagcgggcgc
    20281 gggcgctcgg cgacacggtc cagatcaagc gggtcgcggc cgcgccgcgg ctgaccctcg
    20341 gccccggcga ggcgatcctc accggcggct cgcggtgctc ggtgtcggcg atcggcgcca
    20401 gcggcgggac ggagtacgtc gtcaccgccg ggcactgcac caacatcggc tcgacgtgga
    20461 cgacgtccgg cggccagacc gttggcacgc gccaggcgag cagcttcccg ggcaacgact
    20521 acggcacgat ccgcaagacg ggctcggtct ccctcaccaa cgcccagctc acccaggtcg
    20581 ggaagccgca ggccggaacc cagatccaga agaagggctc cacgacgggc acgacgtccg
    20641 gcaccatccg cggctacaac cgcacggtca actaccagga gggcgcggtc agcggcctga
    20701 tcgagaccac cgcgtgcgtc cagcccggtg acagcggcgg ctcgctccag tcgggcagca
    20761 cggccatcgg catcacctcc ggcggcacga ccgggagctg ccgcagcggc ttccagtcct
    20821 acttccagcc gctggacgag gcgctccagt cccagggact caccctgaag cggtagccat
    20881 cccgcagatg tggggctccc gaacccccgc cgggagcccc acattcattt tcagccgata
    20941 tccgccccgg cggcgcgcgc gcattccgcg tgggcgacgt gacatccatt tccgccgggc
    21001 tccgtggtct cggatcgcgg ggacggctcc gcgccgagca gttcgcgcgc acgtggcttc
    21061 tcgaaaccga tgctgatgtc gccggccttc atctccgtca ggcagaacat gcagagcgcc
    21121 ttcgtcgcct cgcgcgtgca gtccgcgtgg ccgaagaagc agggcttccc gccggggtca
    21181 acgcccgccg cccgctcgac cggctcctcg ccgagcacgt cccgcgcgta cggccgctcg
    21241 atgaacgcca tctcctcacc cggcaggatc ccccgcaggc agaacatgca gacctcttcc
    21301 tgcgcgtcgc gcaggcactc gatgtgagtg aggaactgct tctccccttg ggggccggtg
    21361 aacgaggccc cctcgggcgg cgccgcgccg agggactccc gcgccttgga ctcggtcagg
    21421 gtggcgaagc gcccgtcgac cggcacggga ctgaggcaga acaggcagac cttgccccgc
    21481 gccaactccg cgaccccagg atgccgcgac ttggcgcgga gccgttgagc ggcgaacgcg
    21541 ccgcccgccg ccgccagcac gaacagtaca acggtgacca gtgtcgtagc tcccacgccc
    21601 gcctcctgcc ttgggacagg ctcggacggt agaccgccct gcgcgggagg ggtcccactc
    21661 ctaccggtta cacaccttgt aggcgaagga gtacgtcatc ccgcccccgg gggagtccag
    21721 tgagagccag ccctcctcgg acgggtcgga tgacttcacc cggatgcgcg tctcaagatc
    21781 aaggaattcc ggcgcgtcgc agcgagcata tttcagttgt gctgtaggca ccatatcggt
    21841 gaattgaagg ttgcccttgt gaccggcgac cgcgtgcatg ctgacgtcgc ttcccgggct
    21901 tccccgccac cgatagctct gcgtgagttc gccgacgact cccgggtcca ggtccgccgc
    21961 gaggcgggtg tcggtactcg cgactgcccc ggtgaaaccc tgcggtatgc ggatgcttat
    22021 gctgaaactg cacgatttct gagcctcttt ggggttcacg tcacccccga cggacgcctt
    22081 gaagttcttg attttgacgt tgaccctgcc cccgtcttcc gagacggaga cttcgcccgg
    22141 acatgcggac cggacgacct gggccttggc ggacggttcc ggcacggcgg acgcggggaa
    22201 cgccgtcagc aggggcaagg cggctgcacc gaccgcgaca agcgccgcgt tcttggtctt
    22261 cttcatggtg cagggcattt cttgtaggcg atgctgtatg ttgctccctc gtccggggaa
    22321 tccagcgata tggagcccgc cttggccggg tcggtcgtct ccacctggag ttgcgtcttc
    22381 aggatgagac tgcgttctgc cccacaaggg aggaatacca gcggcgttac gtcttcgaat
    22441 tgccaggtcc gggtcggggc gttgatcgca tgtgaaatct cgtgggccgg tgtgcccgag
    22501 acttggtatt cg
//
