LOCUS       NZ_CP075054            28890 bp    DNA     circular CON 25-MAY-2024
DEFINITION  Bacillus velezensis strain VTX20 chromosome, complete genome.
ACCESSION   NZ_CP075054
VERSION     NZ_CP075054.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 3891321)
  AUTHORS   Vu,T.H.N., Nguyen,V.T., Bui,T.L., Quach,N.T. and Phi,Q.-T.
  TITLE     Probiotic bacterium Bacillus velezensis VTX20 capable of producing
            extracellular polysaccharides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3891321)
  AUTHORS   Vu,T.H.N., Nguyen,V.T., Bui,T.L., Quach,N.T. and Phi,Q.-T.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2021) VAST-Culture Collection of Microorganisms
            (www.vccm.vast.vn), Institute of Biotechnology, Vietnam Academy of
            Science and Technology (VAST), 18 Hoang Quoc Viet, Hanoi, Vietnam,
            Hanoi 100000, Viet Nam
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Link v. 7.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 197.0x
            Sequencing Technology :: PacBio RS II (Pacific Biosciences, Menlo
            Park, CA, USA)
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018415955.1-RS_2024_05_25
            Annotation Date                   :: 05/25/2024 04:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,861
            CDSs (total)                      :: 3,743
            Genes (coding)                    :: 3,682
            CDSs (with protein)               :: 3,682
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 37 of 61
            Pseudo Genes (incomplete)         :: 35 of 61
            Pseudo Genes (internal stop)      :: 14 of 61
            Pseudo Genes (multiple problems)  :: 22 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2689456
            Orig. end                         :: 2718346
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP075054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28890
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="10"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..28890
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28890
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18890](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18890)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(17..28)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(204..219)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.13"
                     /tool="antismash"
     CDS             complement(236..337)
                     /gene="allorf_2689692_2689793"
                     /locus_tag="allorf_2689692_2689793"
                     /protein_id="allorf_2689692_2689793"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSYVCHLEVNRRSQKAARLEAAFYYRQSCRRWR"
     CDS_motif       complement(272..337)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSYVCHLEVNRRSQKAARLEAA"
                     /locus_tag="allorf_2689692_2689793_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(236..271)
                     /prepeptide="core"
                     /locus_tag="allorf_2689692_2689793_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1602.8"
                     /monoisotopic_mass="1601.8"
                     /core_sequence="FYYRQSCRRWR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSYVCHLEVNRRSQKAARLEAA"
                     /leader_location="[271:337](-)"
     gene            complement(339..851)
                     /locus_tag="KH277_RS12880"
                     /old_locus_tag="KH277_12880"
     CDS             complement(339..851)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154857.1"
                     /locus_tag="KH277_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12880"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_012117362.1"
                     /transl_table=11
                     /translation="MEDLLFEYKRTLKETKKWYKQLEEADETVLTSEELKDKKIIRTII
                     TDVEYVIEWLEKGRQPGIRRAIDRRDAYQRMLIKDPRIIETYSQALMFEPSANVTEEDR
                     IRLRDALAVLTDREKEMLLLHKAECFSYERIAALLNVKKSTVQTTVKRALLKIQKQQEQ
                     RNQSPAS"
     gene            complement(964..1167)
                     /locus_tag="KH277_RS12885"
                     /old_locus_tag="KH277_12885"
     CDS             complement(964..1167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936455.1"
                     /locus_tag="KH277_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12885"
                     /product="XtrA/YqaO family protein"
                     /protein_id="WP_043867014.1"
                     /transl_table=11
                     /translation="MNPKKLTDIEHTTLKSQLEEGKIRVIIVDGLKKEAWLAEAPEHGK
                     TLVETRKGDLARVEYEIGFKLN"
     gene            complement(1157..1498)
                     /locus_tag="KH277_RS12890"
                     /old_locus_tag="KH277_12890"
     CDS             complement(1157..1498)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015239676.1"
                     /locus_tag="KH277_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12890"
                     /product="hypothetical protein"
                     /protein_id="WP_003154861.1"
                     /transl_table=11
                     /translation="MQEKNSPAPWRAVHSGEEKPIYIYSAYSEADKEKFPYSNGRLIAA
                     VFNLSSYSQHINAALMAKAPELFEAAETALRLLRGESSEEKEAFINELGSLIHEVNILK
                     KTEDVKHES"
     gene            complement(1596..1763)
                     /locus_tag="KH277_RS12895"
                     /old_locus_tag="KH277_12895"
     CDS             complement(1596..1763)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154863.1"
                     /locus_tag="KH277_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12895"
                     /product="hypothetical protein"
                     /protein_id="WP_003154863.1"
                     /transl_table=11
                     /translation="MCKLCGPKKVIVTETGFGAVFHPCPNCKTGTDLTPVIKRLERMVQ
                     DAKARLDARV"
     CDS_motif       complement(1707..1763)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCKLCGPKKVIVTETGFGA"
                     /locus_tag="KH277_RS12895_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1596..1706)
                     /prepeptide="core"
                     /locus_tag="KH277_RS12895_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="4025.7"
                     /monoisotopic_mass="4023.2"
                     /core_sequence="VFHPCPNCKTGTDLTPVIKRLERMVQDAKARLDARV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCKLCGPKKVIVTETGFGA"
                     /leader_location="[1706:1763](-)"
                     /alternative_weights="4043.7"
     gene            complement(1763..2563)
                     /locus_tag="KH277_RS12900"
                     /old_locus_tag="KH277_12900"
     CDS             complement(1763..2563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007407283.1"
                     /locus_tag="KH277_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12900"
                     /product="ATP-binding protein"
                     /protein_id="WP_043867013.1"
                     /transl_table=11
                     /translation="MTKRTIEQILADLKNGKRPLLADRPEESDESRFDCPLCKDQGGYL
                     KNQLGMEVWVKCRCAAERKVERILGASEITDAFRKLNFKGFITRGKPQAVVDAYECALE
                     YVENFDKMKNCRKNSIALLGRPGSGKTHLLTALSNYVMRQKQTPVLYFPFVEGFTDLKN
                     DFDLLDAKLGRMKQADVLFIDDLFKPLNGKPRATDWQIEQMYAVVNYRYLNHKPVLISS
                     ELACDGLVQVDEALGTRIYEMCSDYLVIINGNSFDVNHRLEGAR"
     gene            complement(2463..3290)
                     /locus_tag="KH277_RS12905"
                     /old_locus_tag="KH277_12905"
     CDS             complement(2463..3290)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417603.1"
                     /locus_tag="KH277_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12905"
                     /product="FaeA/PapI family transcriptional regulator"
                     /protein_id="WP_014304841.1"
                     /transl_table=11
                     /translation="MNRKSYPFFIYSGLLNSEHYDKIGSAIWLFLWFISSTTKEHVKDG
                     IKWGIVLGHKPVKAREMADVFAVSEKTVRRWLESLEQHEYIKTVRAPYGLIVSVKHSKR
                     FTPKKTLTRPEATDRTISADHRDKNVRREIDITKNHTAEEAINEIAAHFIRLRSAQEGR
                     SVYPSPRDYQAIARIVSLGASAQEAIKWLGECFTAFEQRRTSSAETIKAFSYCAKFMED
                     RLNARIAGRTITTKKERNTIHDKTNDRADTGRPEKRKTSITGGQTGRIRRKPL"
     gene            complement(3280..3459)
                     /locus_tag="KH277_RS12910"
                     /old_locus_tag="KH277_12910"
     CDS             complement(3280..3459)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154869.1"
                     /locus_tag="KH277_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12910"
                     /product="hypothetical protein"
                     /protein_id="WP_003154869.1"
                     /transl_table=11
                     /translation="MQPIIIRFSSNPADQRCLGKAGGSISFTACGLPVFRFDNRLQYER
                     YIRLKKNGDVPYES"
     gene            3651..3989
                     /gene="xre"
                     /locus_tag="KH277_RS12915"
                     /old_locus_tag="KH277_12915"
     CDS             3651..3989
                     /codon_start=1
                     /gene="xre"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389133.1"
                     /locus_tag="KH277_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12915"
                     /product="HTH-type transcriptional regulator Xre"
                     /protein_id="WP_003154871.1"
                     /transl_table=11
                     /translation="MIGGRLKSLRGKKTQEEVANHIGVSRARYSHYENGRSEPDYDTLQ
                     KLADYFKVSTDYLLTGKEPSDEDMFADPDLQIAYRDMQDFSPESKQQAIEFINYLKEKE
                     KNRRPKHK"
     misc_feature    4046..4059
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.38"
                     /tool="antismash"
     misc_feature    4109..4122
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.52"
                     /tool="antismash"
     gene            4138..4728
                     /locus_tag="KH277_RS12920"
                     /old_locus_tag="KH277_12920"
     CDS             4138..4728
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936463.1"
                     /locus_tag="KH277_RS12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12920"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_003154873.1"
                     /transl_table=11
                     /translation="MGDFLTHLEEYVKNLYCRMGMTAPLHIDMQMIAKELDIWIHFEDT
                     HSMMLKRDGMYSIVLNQKKSPEEQWQDFAHELCHVLKHTGNHFHMNKLFRELQEFQANH
                     FMYHFCVPTFMLLNMELPQRRSHAVILIAAAFRVTASFAEKRLELFERRKAGIQFQKRL
                     ACLLSDKRPNVYYGSGQTHLHAAEEKTPYFIEN"
     gene            complement(4883..5488)
                     /locus_tag="KH277_RS12925"
                     /old_locus_tag="KH277_12925"
     CDS             complement(4883..5488)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417516.1"
                     /locus_tag="KH277_RS12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12925"
                     /product="poly-gamma-glutamate hydrolase family protein"
                     /protein_id="WP_032858666.1"
                     /transl_table=11
                     /translation="MKDRYDNFAALSAAESEYRIIYEEKEGSKCIVLAPHGGRIEPGVS
                     ELVQAFSDQSSIYLFEGTKRCDNRSLHLTSTRFDEPLALEKVTAHHYALAFHGYHDLKK
                     ANTLVGGADLEKARLICDLLREAGFDAELTEKNDRLAGVNPGNIVNRTKRKMGLQLEVS
                     TAQRHALFSNFGCRGEKYTPTDLFFRYVETVKAGFYDK"
     gene            5598..5975
                     /locus_tag="KH277_RS12930"
                     /old_locus_tag="KH277_12930"
     CDS             5598..5975
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389129.1"
                     /locus_tag="KH277_RS12930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12930"
                     /product="PH domain-containing protein"
                     /protein_id="WP_213390661.1"
                     /transl_table=11
                     /translation="MGFINGLLGNASTISTAEAKSELARILLEGENVNATFKLVRDIIV
                     FTDKRLILVDKQGLTGKKTEIQSIPYKSISRFSVETAGRFDLDSELKIWISGAELPAVS
                     KQFKKDESIYDIQKALAAVCM"
     gene            complement(6013..6966)
                     /locus_tag="KH277_RS12935"
                     /old_locus_tag="KH277_12935"
     CDS             complement(6013..6966)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389128.1"
                     /locus_tag="KH277_RS12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12935"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_032858665.1"
                     /transl_table=11
                     /translation="MGIEVKKRLVSADKYALKCPNPMTPEYITIHNTANDASAANEISY
                     MTGNSESTSYHFAVDDKEVIQGIPLDRNAWHSGDGTNGTGNRKSIAIEICYSKSGGERY
                     RAAEELAIAFAAQLLKERGWGIDRIRKHQDWNGKYCPHRILSEGRWDEVKAKIEKKLSG
                     SMPAKKASISSSASEYHVKKGDTLSEIAASHGVSVKSLQSINHITDPNHITVGQVIKLA
                     QTGSSSKSQAVSSYPLPSGVIKVTKPLTKGTNVKQVQNALSALYFYPDKGAKNHGADGV
                     YGPKTAYAVKRFQSVSGLTADGIYGPKTKAKIEEKL"
     misc_feature    7061..7074
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.57"
                     /tool="antismash"
     gene            complement(7109..7243)
                     /locus_tag="KH277_RS12940"
                     /old_locus_tag="KH277_12940"
     CDS             complement(7109..7243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012117358.1"
                     /locus_tag="KH277_RS12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12940"
                     /product="PhrA family phosphatase inhibitor"
                     /protein_id="WP_003154881.1"
                     /transl_table=11
                     /translation="MKSKLLSGLLLVAVGFSFTQVIGHESHLENQADGTFHIAARNQT"
     gene            complement(7233..8369)
                     /locus_tag="KH277_RS12945"
                     /old_locus_tag="KH277_12945"
     CDS             complement(7233..8369)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389125.1"
                     /locus_tag="KH277_RS12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12945"
                     /product="Rap family tetratricopeptide repeat protein"
                     /protein_id="WP_087920760.1"
                     /transl_table=11
                     /translation="MRMKQTIPSSFVGLKINEWYTHIRQFHVLEAERVKREVEREIEDM
                     EEDQDLLLYYSLMEFRHRVMLDYIKPLKEDPSQPEFSELLEDIEGNQYKLTGLLDYYFN
                     FFRGMYEFKQKMFLNAMMYYKRAEKNLALVSDDIEKAEFAFKMAEIFYNLKQTYVSMSY
                     AVQALETYQSYETYNVRRIQCEFVIAGNYDDMQYPERALPHLELALDLAKQEGNPRLIS
                     SALYNLGNCYEKMGDLSKAAEYFETSVSICRSEKFDNLPHSIYSLTQVLYKQNTTAEAE
                     KQYRLGLSIAREYNDELFVNLFQFLHALYGKEMDNASVRHTFDFLEEHMLYPYVEELAH
                     DAAKFYMKHGQPEKALTFYEKMVHAQKQIQRGDCLYEI"
     gene            8574..9041
                     /locus_tag="KH277_RS12950"
                     /old_locus_tag="KH277_12950"
     CDS             8574..9041
                     /codon_start=1
                     /function="Uncharacterized protein conserved in bacteria"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417598.1"
                     /locus_tag="KH277_RS12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12950"
                     /product="DinB family protein"
                     /protein_id="WP_014304838.1"
                     /transl_table=11
                     /translation="MTAQNQLVSHFLSHRNVTIELAEKISREHYDYKPAETSMSAQELV
                     KHIVYSFLMFANVINDGNGSAIQNKPKEEAETDLVKLAEACTEKTTDILSQLTEEQLNR
                     EIDLTASFGRKITGAALLQLAMEHEIHHKGNLFVYVREMGHTELPFYQQKS"
     misc_feature    9106..9120
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.28"
                     /tool="antismash"
     gene            9190..9954
                     /locus_tag="KH277_RS12955"
                     /old_locus_tag="KH277_12955"
     CDS             9190..9954
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389122.1"
                     /locus_tag="KH277_RS12955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12955"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_015388360.1"
                     /transl_table=11
                     /translation="MTVSIVFMGFFVGTLVGLTGVGGAALLTPLLIVLGINPSIAVGTD
                     LLYNSITKLFGVVSHWKQRTVQFKLVGYLALGSIPSATAAIGILHLFPAFHQHQEQIIK
                     QALGYVLTLVAISIIARLFFDKKLRPNRWQQKTLEEKRTLMILIGVIFGFIVGLTSIGS
                     GSLFAIAMLYLFRMKTAEVVGTDIAHAFLLVTVAGLLNASFGSVDYLLVLNLLIGSVPG
                     VLLGSFFSPKFSPRPLQFVMAAIILISGIKLI"
     gene            complement(10001..12886)
                     /locus_tag="KH277_RS12960"
                     /old_locus_tag="KH277_12960"
     CDS             complement(10001..12886)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154888.1"
                     /locus_tag="KH277_RS12960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12960"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_165625612.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-84, bitscore:
                     282.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-54, bitscore:
                     183.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTQNSANYVYENSMLNIFKEEDYFEGFAQYYISIFKAQIVKEI
                     DRIPSESLLDKGCLVESILINYKKKIYYLAGKTLIHEFHQTFDEFDEKNESKNYDIFSE
                     RLKNSAFVEEILNNYPVLQDLISRSTSDFIRFTISIIKHWVNDYKKIQQKFNFSFGKMR
                     KVNMNAGDVHNGGKSVVIIEFENNKLVYKPRSLEIDVFYEKVIDYVNQYYQTNLKTPLS
                     LDQGEYGWQEYVQSEPCDNIEQVRNYYYQFGMHLGFIYAFQGSDFHFENIIACRDKPVL
                     VDLETLFQSSLFFSEENKENVNLMASAQVNKTILKSALFNYMSFPEDNGLTNIGGLINT
                     ENQKGEKEEVLHIKTDKISIRKKQYLFKRGRNLPVYKNKVAECFEFEREFIEGFKRIFL
                     ILKEDLYIRNLISELNYAPIRIIVRPTYVYASFLETLLHPMYLKDYGERIRVLSFIKDA
                     YTKYEVFDSISPFEIKDMMIGDIPYFNAPISEKRVYSNSIHVVDTGIMKQSAKQEVLTR
                     LANMSEEDMHQQVSLINMALSSTAANLDIIYKNQIDDFVPGYLKNDIQIKELIQIETDC
                     ILKQAIESEKYLQWVSIVSAPNGTLSVGPLSFGLYDGLAGVGLYFSAYDFNYNDEKVKS
                     ILRKIVNSINQIYEHSIYKTNFSAFYGSSSYIYFVNKMRGTGLYSENEVNSMCKAYLEK
                     LRQETAQITHTDFIGGLAGILKVVIQLGRYYRTELMEDTARAVCKEICKRMIQNRNEAY
                     WKSDADENVVLAGFSHGITGICYALSEYYAHIEASGEVLRLIESALKYEDKFFDTKIKK
                     WRDNRKNESDYSSAMWCHGSCGILLGRSRIYENVDGRIHVGYINESLDDTLLNGNSHRQ
                     GYSLCHGTMGNIDVLHAIKELSLFKNRKQEIENTINIWVNHFKETLLKNGWQNGIRNDH
                     SGLGMMLGKTGQLYALLRLVNKEIPTPLALD"
     gene            complement(12975..13151)
                     /locus_tag="KH277_RS12965"
                     /old_locus_tag="KH277_12965"
     CDS             complement(12975..13151)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="KH277_RS12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12965"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417596.1"
                     /transl_table=11
                     /translation="MKKDFQALTPMTEEELKNLAGGSDATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       complement(13086..13151)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDFQALTPMTEEELKNLAGG"
                     /locus_tag="KH277_RS12965_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12975..13085)
                     /prepeptide="core"
                     /locus_tag="KH277_RS12965_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3391.9"
                     /monoisotopic_mass="3389.7"
                     /core_sequence="SDATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDFQALTPMTEEELKNLAGG"
                     /leader_location="[13085:13151](-)"
                     /alternative_weights="3409.9"
                     /alternative_weights="3427.9"
                     /alternative_weights="3446.0"
                     /alternative_weights="3464.0"
                     /alternative_weights="3482.0"
                     /alternative_weights="3500.0"
                     /alternative_weights="3518.0"
                     /alternative_weights="3536.1"
                     /alternative_weights="3554.1"
     gene            complement(13188..13364)
                     /locus_tag="KH277_RS12970"
                     /old_locus_tag="KH277_12970"
     CDS             complement(13188..13364)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="KH277_RS12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12970"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417595.1"
                     /transl_table=11
                     /translation="MKKEFLALELMTEEELKELAGGSEATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       complement(13299..13364)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKEFLALELMTEEELKELAGG"
                     /locus_tag="KH277_RS12970_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13188..13298)
                     /prepeptide="core"
                     /locus_tag="KH277_RS12970_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3405.9"
                     /monoisotopic_mass="3403.7"
                     /core_sequence="SEATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEFLALELMTEEELKELAGG"
                     /leader_location="[13298:13364](-)"
                     /alternative_weights="3423.9"
                     /alternative_weights="3442.0"
                     /alternative_weights="3460.0"
                     /alternative_weights="3478.0"
                     /alternative_weights="3496.0"
                     /alternative_weights="3514.0"
                     /alternative_weights="3532.1"
                     /alternative_weights="3550.1"
                     /alternative_weights="3568.1"
     CDS             complement(13387..13569)
                     /gene="allorf_2702843_2703025"
                     /locus_tag="allorf_2702843_2703025"
                     /protein_id="allorf_2702843_2703025"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKGGEIWNMKENFSALYETSEQELRELIGGQNSVSITTIPITNHV
                     CPTITVGCACPQRQV"
     CDS_motif       complement(13480..13569)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKGGEIWNMKENFSALYETSEQELRELIGG"
                     /locus_tag="allorf_2702843_2703025_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13387..13479)
                     /prepeptide="core"
                     /locus_tag="allorf_2702843_2703025_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.70"
                     /molecular_weight="3055.5"
                     /monoisotopic_mass="3053.6"
                     /core_sequence="QNSVSITTIPITNHVCPTITVGCACPQRQV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKGGEIWNMKENFSALYETSEQELRELIGG"
                     /leader_location="[13479:13569](-)"
                     /alternative_weights="3073.5"
                     /alternative_weights="3091.6"
                     /alternative_weights="3109.6"
                     /alternative_weights="3127.6"
     gene            complement(13571..15718)
                     /locus_tag="KH277_RS12975"
                     /old_locus_tag="KH277_12975"
     CDS             complement(13571..15718)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154889.1"
                     /locus_tag="KH277_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12975"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_003154889.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.1e-26, bitscore:
                     90.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKRKLPVILQRNQFDCGITCLAMVLSRAEGIKINPNKLKLNK
                     EIIGRDGTDLIEMKRISETFDYDFKAFRTDNITQLKELNKNHPLIVHWNHNHFVVVDAF
                     GTDNVKIIDPSSGRLTITLEEFKTFYNGISIMLIRKNELERKDKTASSLKDVSSFRKIG
                     KYLLKDKKLLGVIISFTFIFQALNLMTPFLTQYIIDSFIDGNEKILPIPMLFMIVIVSI
                     VLFFSLSLIRMKFIIKLQLKINKSMTDKIIHKIFSLPLKFFEANTAGDISTRIHNIAVI
                     REVISRLASTLILDISLIFVFFIVMFVYSPILSFIVLLGAAIQVMSTKILLPKIEMFTK
                     QEVNSQSNFQSQLIEILRSMTFIKTIGETRNIESQLNYNFNHQLDYFSKRMNYSSLLGA
                     VSNAINLSLPLLILIVGTWSAVSIGLTLGAVIAFSNIAGRFMSPLGSIIGSLESIKLVE
                     EMVDRVEAVLDEKDEEINDKSIELFNPAAHNISLKNIDFSYNGNDYILNNINLMIRPRE
                     KITLIGKTGSGKSTLIKIIAGLYQKTAGEICYGEFKIEDVNMVKLRETLGYIVQDVNLF
                     NDTIINNIKYFNEKITMEEVVQAAKEACIHEDIIKMPMGYHTMIGENGITLSGGQRQRI
                     SIARVLAKNPRILFIDEGTSNLDKDTELNILNNIYKKDITVISITHRTEWLEFSESVYE
                     IENGNLKTIKTKYESQLQQTY"
     gene            complement(15708..18890)
                     /locus_tag="KH277_RS12980"
                     /old_locus_tag="KH277_12980"
     CDS             complement(15708..18890)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154890.1"
                     /locus_tag="KH277_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12980"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_043867010.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-99, bitscore: 332.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5e-60, bitscore:
                     200.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLTNILLSKEKKAAVSQFDENEKLFDRNLELIYKNDIQMAQES
                     IYNVLSIQSIDKVKSLYQTPLHKSAFTVHVFENLKKGIAHQAIKKEDVNEEIMFHVFAL
                     KVSSYFNDLLKKSKFPSYDYLLEQPALFHHSISNQLEKIILKVSYRTLVLDMNMNREKG
                     FLAGETPKEKYGDYNKTLLCSQEYLEIFFQRYPVLLRVIGNELRKFKKFILEFISRFEK
                     DKPELLSLFGFSEQVKIRDIEVGMGDSHSDGRKVTKITLNEGKLIYKPRSLEIDLLYKK
                     IIEFLNEKIRDHDIKLSTPNVLSRDGYGWTEFISFKACNCLKDVQNFYQRTGAQIGLLY
                     ALKAVDFHSENLIANGSYPVLIDLESLFHPAYQKKKDGMDAYEKAETQLHESVRALGLL
                     PFFFAGKADISGIGRKGKAKSIIKVPQLINLKTAEMSVKRDYVEIDTANNHPMLENKFV
                     YAKDYVEELKQGFSKAYMTILKHASELIRIIEKSENKIYVRFISKPTIKYSALLELSFH
                     PRFLHNSIDREIFLSKIWERPKQEDEYQSIVKYEFNDLINNDIPYFKVKLNEKDLLSSK
                     NKKIENYFPETPAQSVKERISNLSKDDLKFQLYVIELSMLASEDDRQIVLKEFITKEPG
                     QYVNVFSSNQESILIEKAEELAAYIYNQSYKAHTDKGSSYSWLNATPIGVDEIQWNLSV
                     MGDTFYDGLSGMAFTYLALWRVTKKEKYLDIAEKIMKDVISRFIDIEVKPDEDSSMSVG
                     AFSGVSSIVYTLMNFYMYTKREKYKQNAKQIAQLIPSLLPYDKELDIIGGTAGALIVMI
                     RSFEIENDTFFLSLAEQCGSFLMKQAIFLDEDFVTWEGIANKPLTGFSHGNAGMIYALQ
                     LLEKHSKHQDISMYIRKGLAFENSKKVNGNWLDLRKTVNEAATSAWCHGSPGILLSRLE
                     LKDSKHPDIAEVAKKDLNKTVSNIFYDGFGREQSLCHGDMGNALILIEYGKKTGESQFV
                     NIGKNLILESVQDKNIGFYQCGVGRDVETPNLMLGLAGIVYGMLYAADAELPNILNLEI
                     GRVDTLGDIYEN"
     gene            complement(18975..19157)
                     /locus_tag="KH277_RS12985"
                     /old_locus_tag="KH277_12985"
     CDS             complement(18975..19157)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154891.1"
                     /locus_tag="KH277_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12985"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_003154891.1"
                     /transl_table=11
                     /translation="MNEKMYRFAGDLREELEEISLSEFSGGGGAEQRGISQGNDGKLCT
                     LTWECGLCPTHTCWC"
     CDS_motif       complement(19092..19157)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEKMYRFAGDLREELEEISLS"
                     /locus_tag="KH277_RS12985_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18975..19091)
                     /prepeptide="core"
                     /locus_tag="KH277_RS12985_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="3895.3"
                     /monoisotopic_mass="3892.7"
                     /core_sequence="EFSGGGGAEQRGISQGNDGKLCTLTWECGLCPTHTCWC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEKMYRFAGDLREELEEISLS"
                     /leader_location="[19091:19157](-)"
                     /alternative_weights="3913.3"
     gene            complement(19349..20014)
                     /locus_tag="KH277_RS12990"
                     /old_locus_tag="KH277_12990"
     CDS             complement(19349..20014)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154892.1"
                     /locus_tag="KH277_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12990"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003154892.1"
                     /transl_table=11
                     /translation="MIKILLIDDHIGVAQGTKAILEKSNKMGVTILSCCKEVLNHLKHY
                     EYDLILLDLYMPELNGMELSKMILRESPDQKIIIYTGFDISVHFNLLVEVGVSGFISKS
                     STEEHMIKVIESVIEGDTIIPTHLFKQLRRTEANTFNIDKLEDRIRDITLNEREQDILA
                     GVAEGMTNRELSAKLLISQRAVEYILTGVYNKLGVKSRTEALIKANRYSLISMKTIYE"
     misc_feature    complement(20013..20027)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            complement(20026..21276)
                     /locus_tag="KH277_RS12995"
                     /old_locus_tag="KH277_12995"
     CDS             complement(20026..21276)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154893.1"
                     /locus_tag="KH277_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_12995"
                     /product="ATP-binding protein"
                     /protein_id="WP_003154893.1"
                     /transl_table=11
                     /translation="MKDNWVKLNIEQFARAFVFSLLLFFMLLLITDSQLQFKQYSLFFV
                     LSIFGSSCLCFTYDDRNKTYLRSLFRFSELCQEGSDADQLIKELTNEIQSVLSGKQIAL
                     INYDKKTLKLKEKNIQVPNINISNFKIGEIRETASGSILFIGEKCDTFVFIHLSHGGHP
                     IKIRENEADWLRMLAFCTASALQNKLLIQKKIDEIIIDDQHKCKSAVLSKVLFSISEIE
                     RTKLAQDIHDSIIQELIFVCRELEYHVEKYKDIYYIREILLDNIQYIREKCFDLRPPFL
                     MEMGLLRSIQVLIDKHKSNYQLDIEFFVDVKDDSIFTEDITINIYRIVQELLTNAVKHS
                     KASYIVLTMIQKKTSLMFVYEDNGIGIDWNKVNSKTNSFGLTGIKERINCMNGIHNISS
                     SVNEGLLLRFEISTKNE"
     gene            complement(21342..21533)
                     /locus_tag="KH277_RS13000"
                     /old_locus_tag="KH277_13000"
     CDS             complement(21342..21533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154894.1"
                     /locus_tag="KH277_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13000"
                     /product="hypothetical protein"
                     /protein_id="WP_003154894.1"
                     /transl_table=11
                     /translation="MEQVIFVISMLALGVTLVTFFGMILNDGLRGVLNFSRKPVKFMTG
                     SFLVYIVAFAVYILISVK"
     misc_feature    21490..21505
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.85"
                     /tool="antismash"
     gene            complement(21551..22282)
                     /locus_tag="KH277_RS13005"
                     /old_locus_tag="KH277_13005"
     CDS             complement(21551..22282)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417590.1"
                     /locus_tag="KH277_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13005"
                     /product="ABC transporter permease"
                     /protein_id="WP_003154895.1"
                     /transl_table=11
                     /translation="MSLLVRNEFLKLKRLKSIYVIFFLSFLPFLINGIGLLTMNENTDW
                     NKFYMFVFNQYSILFPTIIFIFSGFYFYLEFKNRTMLNWMSYPYHKFKLILSKLAAAFL
                     FLFLISAVNHIIHLSTLFFFFREDISASDLLRLIATSFTSTTLSLLTIPIAALIAFLSK
                     NLVVVMITGVASFLIMTILLASDVSIVFPFSFIYRFSIQIFESDMGYTNSILLVWGLLI
                     MGLYVLVSLSGLYVYSKKNRM"
     gene            complement(22263..23198)
                     /locus_tag="KH277_RS13010"
                     /old_locus_tag="KH277_13010"
     CDS             complement(22263..23198)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417589.1"
                     /locus_tag="KH277_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13010"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_052585736.1"
                     /transl_table=11
                     /translation="MGKADPALISKGINVSIKKKEILHDINLTLEKGKIYGLLGPNGAG
                     KTTLLKVLLGIFPPTSGEVIFEENDLYENPNNDVIQSIGSIIEFPGFYENLNLFENIKL
                     HLNYLKKSASDEEINEILGKVGLFEHKDKLFSQTSLGMKQRLGIARAVAHAPALLLLDE
                     PTNGLDPYGIKEVREMLIQEVMKNGTTVVISSHLLSEINLMADELLIMNKGQIIFESAF
                     MKNTQHLYLYKIPAEAGINWADIEKFADHVISKNKQQFEFISIIHPSEMKEKLNSWGFN
                     KASIDGFKLSLEDLYLKLLAKEKGHESVSA"
     misc_feature    23290..23304
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            complement(23318..24676)
                     /locus_tag="KH277_RS13015"
                     /old_locus_tag="KH277_13015"
     CDS             complement(23318..24676)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417588.1"
                     /locus_tag="KH277_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13015"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_003154898.1"
                     /transl_table=11
                     /translation="MKLSTKYLINIVASILFFPIAFLGVNFLYYVTLTYLIDHQGQVHY
                     EPNKLESDWKSDVEGFSGKSNREITSAFPHMKQYKHSDIVWINDKGKVMFSNSERLAKK
                     GEVIHVSELIKLMEQNQKKYLLLSAYVNGSEDSGYAFLETPRSIIGSQWEVMRAKYSYI
                     WFIALIFVCSLFVINSWMFFAKIQKRLISLGNHMKKQDNDGIPEFVTVKQKDELGQVEY
                     SFNQMVEELRNSRQKEREEGEIRKNLIADLSHDLRTPLTVIRGHTFTLKNEISSENGKH
                     SLGIINDKITFMGELIDNLSSFSLLAAGKLPLHKKSCDILKIIRSSLTAWYPIFEKEHF
                     TIDIDLKENIVWEIDETWLKRILDNIFQNVLRHAHSGKYVSVQTKLIENKPVIIIEDRG
                     PGMNYKSERKGAGIGLSIINMMLKQMGLEHKIKSNQNGTVFIIYPNSNEYVKP"
     gene            complement(24673..25344)
                     /locus_tag="KH277_RS13020"
                     /old_locus_tag="KH277_13020"
     CDS             complement(24673..25344)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154900.1"
                     /locus_tag="KH277_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13020"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003154900.1"
                     /transl_table=11
                     /translation="MNNILYIEDDQEIGQFVKDDLEDRGYMIIWLTSSYNYETYIEKAD
                     LIVLDIMMPGLDGFTIGQRMKKTHPQIPLLLLTARTGLEDKLKGLGFADDYVTKPFHPD
                     ELAARIEVLLRRFDKTAIHELKLKHLSVHLKEKRILNHQSHEEIFLTDKQLRIFLLLLR
                     HPNQILTKEQIYENIWEQPYIEGDKTLMVHIRHLRQKIEINPNEPEILETIRGIGYRIK
                     Q"
     gene            complement(25528..27021)
                     /locus_tag="KH277_RS13025"
                     /old_locus_tag="KH277_13025"
     CDS             complement(25528..27021)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389121.2"
                     /locus_tag="KH277_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13025"
                     /product="altronate dehydratase family protein"
                     /protein_id="WP_213390662.1"
                     /transl_table=11
                     /translation="MKEVIKIHKNDNVLLAMRHFNKGERLYTDGLAIEVKDPVKRGHKI
                     ALQTIEENGSIIKYGFSIGRATRRISAGEHIHTHNLQTNLSDVQEYTYSPRFEDNPFTN
                     ENRTFKGYKRENGTSGVRNELWIVPTVGCVNGVAEKILQRFVKEAKDIAPFDNVLVLKH
                     QYGCSQLGDDHENTKQMLINAIRHPNAGGVLVLGLGCENNELAAIKETLSEVNGDRVKF
                     LESQAVTDEIEAGTALLKEIHLAAKGDKREEIPLSELSIGLKCGGSDGFSGITANPLLG
                     RFSDYLIAQGGSTVLTEVPEMFGAETILMQRAVSEEVFHKTVRLINDFKQYFMKHEQPI
                     YENPSPGNKEGGISTLEDKSLGCTQKAGLAPVSDVLTYGETLKTKGLTLLSAPGNDLIA
                     SSALAAAGCHIVLFTTGRGTPFGTFVPTVKVSTNTDLFQSKPHWIDYNAGRLAEDQTTV
                     DHIVRDFIQYIIKVASGQYVNNEKNDFRELAIFKSGVTL"
     gene            complement(27018..28463)
                     /locus_tag="KH277_RS13030"
                     /old_locus_tag="KH277_13030"
     CDS             complement(27018..28463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015388365.1"
                     /locus_tag="KH277_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_13030"
                     /product="tagaturonate reductase"
                     /protein_id="WP_213390663.1"
                     /transl_table=11
                     /translation="MRQLNKKMCGEYIQYPEKVLQFGEGNFLRAFADWQIDQLNQLTDF
                     NGSVVAVQPRGSEKIKRLNEQDGLFTLFLQGIKDGKPAEEHTIVKSISRGIDLFSDYDS
                     FKRLAAQEDLRFIISNTTEAGITFEKGDRLEDRPQKTFPGKLAAFLYFRYKAFAGDAEK
                     GCIVLPCELVEENGRKLKAAVLQYAGLWELEPDFTQWIHDANIFCNTLVDRIVPGFPVD
                     TAEELTDFLGYEDRLLVVGEHYYLWVIEGPEQLQNELPFADAGLNALITSDLTPYRTKK
                     VRILNGAHTALAPVALLYGLLTVREAAEHEVTGRFIEELINEEILPVLQMEGVTQYAAD
                     VLHRFKNPYIQHYLQSITLNAAAKFKTRNLPTLKAYIEQEGRLPERLVFSFSAMIYSYW
                     NGLNKPADGEEVLNRFQMARSRCKDDMFQAAFSILGEERLWGKNLNHLPGLTERTAFFL
                     SVIHKRGMKHALHECCGNKGEVE"
ORIGIN
        1 gacaaaacag ccgctggcgt tcgtttaact catcaccttc gcccgggttg ttttttccgc
       61 cgctttccgc gttcttatta agcgcctcgt cccagcgccc ttcttttttc catctgccga
      121 ttgttcttgc ggatacgcct gatttgccgg caagggcgcg atttgtgatg cggcctttat
      181 gagactgata gattgtaaat gcctgttctc tttttgcgtt tttcatgcta cggcatcacc
      241 gccacctccg acatgattgt ctataataaa aagcggcttc taatcgggcc gctttttgtg
      301 atcgtctgtt cacttctagg tggcaaacgt atgacaactt atgaagcagg cgattgattt
      361 ctttgttcct gctgtttttg aattttcaga agcgcccgtt tgaccgtcgt ttgtacggtt
      421 gatttcttta cattcagcaa ggcggcgatc cgttcatacg aaaagcattc cgctttgtgg
      481 agcagcagca tttctttttc tctatccgtt aaaacggcta atgcgtcccg cagtctgatt
      541 ctgtcttctt cagtcacatt tgcggacggt tcaaacatca gcgcctgcga ataggtttct
      601 atgattctcg gatctttaat gagcattctc tgataagcgt ctctgcggtc tatcgctctt
      661 cttatgccgg gctgccggcc tttttcaagc cattcgatga catattccac atctgtaatg
      721 atcgttctga tgattttttt atctttcagt tcttctgaag taagcaccgt ttcatcggct
      781 tcctccagct gcttgtacca ctttttcgtc tctttcagcg tgcgtttata ttcaaatagt
      841 aagtcttcca tgtagatcct cctctttttc ggaacaaaaa aggacaccaa tcaatgcgca
      901 gcatgtgcgc gattgatcag tgtccgcagg ctttccgtct tggacgtatt ctgttttttt
      961 cgattaattc aatttaaagc cgatttcata ttcgacccgg gccagatccc cttttcgcgt
     1021 ttcgacaagc gttttgccgt gctccggcgc ttcggcgagc catgcttcct tcttcagtcc
     1081 gtctactata atcacccgaa tcttgccttc ttccagctgg ctttttaatg ttgtatgttc
     1141 aatgtcagtc agttttttag gattcatgtt ttacgtcctc cgtctttttc aaaatgttca
     1201 cttcatgtat gaggcttccg agctcattta tgaacgcttc tttttcttca gaactttctc
     1261 cccggagcag gcggagagcc gtttcggccg cctcaaagag ttccggggct ttcgccatca
     1321 atgccgcgtt gatgtgctgt gagtatgaac ttaagttgaa aacggccgcg atgagccttc
     1381 cgtttgaata agggaacttc tctttatccg cttcgctgta agcggaataa atgtaaatgg
     1441 gtttttcttc tccgctgtgt acggcccgcc atggagcggg gctgtttttt tcttgcaatg
     1501 gtgatcctca ctttccatca gcctcatgcc atgcttcaat ttgcttttct atccgttttg
     1561 ccctgaacag caggcaaaaa agccatttga tatatttaca cacgtgcatc aagcctcgct
     1621 tttgcgtctt gaaccattcg ttcaagccgt ttaatgaccg gcgttaaatc agtgcctgtt
     1681 ttgcagttcg ggcaagggtg aaagacagcg ccgaaacccg tttccgtcac aatgaccttc
     1741 ttcggtccgc acagcttaca cattatctcg ccccctctaa tctgtggttt acgtcaaatg
     1801 aattgccgtt aatgatgact aaataatcgc tgcacatctc ataaattctt gtgcccaagg
     1861 cttcatcaac ctgcaccaat ccgtcacagg ccagctcgct cgagataaga accggcttat
     1921 gatttaaata gcggtaattc acgacggcat acatttgttc aatctgccaa tcggtcgccc
     1981 ggggttttcc gttcagcggt ttgaacagat cgtcaataaa aagcacatcc gcctgtttca
     2041 tacggccaag ctttgcatca agcagatcaa aatcattttt taaatccgta aagccctcca
     2101 caaaaggaaa atacagcacc ggtgtctgct tctgtctcat gacataattg ctgagagcgg
     2161 tcaaaagatg ggtttttccc gaccccggac gccctaaaag ggcaatgctg tttttccggc
     2221 agtttttcat cttgtcgaag ttctcaacat attcaagggc gcactcatat gcgtcgacga
     2281 ctgcctgagg cttgccccgc gtgataaatc ctttgaaatt cagcttccga aaggcatctg
     2341 taatttcact tgcgccgaga atgcgttcta ctttccgttc ggcggcgcag cggcacttca
     2401 cccacacttc cattcccagc tggtttttga gataaccgcc ctgatcttta cagagcgggc
     2461 agtcaaagcg gctttcgtct gattcttccg gtctgtccgc cagtaatgga cgttttccgt
     2521 ttttcaggtc ggccagtatc tgctcgatcg ttcgttttgt catgtatcgt attcctctct
     2581 ttttttgttg tgattgtcct tcccgcaatt cgtgcattca agcggtcttc cataaacttg
     2641 gcgcaatagc tgaaagcctt gatcgtttca gctgaagagg tgcgccgctg ttcaaaagcg
     2701 gtaaagcatt cgccgagcca tttgattgct tcttgtgctg acgcaccgag ggaaacaatc
     2761 cgggcgatgg cctgataatc ccggggcgac gggtatacgc tccgcccctc ctgtgcagac
     2821 cttaatctga taaaatgggc ggcaatttcg ttaatcgctt cttcagcagt atgatttttt
     2881 gttatatcta tttctctccg gacatttttg tcccggtgat ccgccgatat tgtccggtca
     2941 gttgcttccg ggcgggttaa tgtctttttc ggcgtgaatc ttttcgagtg ttttacggag
     3001 acgatgagtc cgtaaggggc gcggacggtt ttgatatact catgctgttc caagctctcg
     3061 agccaccgcc tgacggtttt ttcgctgacc gcgaatacat cggccatttc tcttgctttt
     3121 acgggcttat gtccgaggac gatcccccac tttatgccgt cttttacatg ttcctttgtc
     3181 gttgagctga tgaaccataa aaacagccaa atggcggacc ctattttgtc ataatgttca
     3241 gaattcaata atccggaata gatgaaaaac gggtagcttt tacgattcat aagggacgtc
     3301 tccatttttc ttcagacgta tatagcgctc atactgcaat cggttatcaa atcggaatac
     3361 cggtagtccg caagcggtaa aagatatcga accgcctgct tttcctaaac atctctggtc
     3421 agccggattg ctgctgaaac ggatgattat cggctgcatc tctcaccctc ctgatcaatt
     3481 tcttatcgta ttttgataca ttttgtatct ctatgatgtt gattatatac gatacatttc
     3541 gtatcatcaa gacctttttg atactttttt tatcatccct ttcttttgat acattttgta
     3601 tctataatca taagtaactt agggtgttga aaaaagagag gtcatttcgg atgataggcg
     3661 gaagattaaa gagtctcaga ggtaagaaaa cgcaggaaga agtcgcaaat catatcggtg
     3721 tctcgcgcgc cagatattct cattatgaaa acggccgatc tgaacccgat tacgacacgc
     3781 tgcaaaagct tgcggattat ttcaaagtgt cgactgatta tttgttaacc ggaaaagaac
     3841 cttcagatga agacatgttt gccgatcccg acctgcagat cgcatatcgg gacatgcagg
     3901 acttttcccc ggaaagcaag cagcaggcca ttgaattcat taattattta aaagaaaaag
     3961 agaaaaaccg caggccgaaa cataaataat ccgctctttt cctttaaact gcttaacgtt
     4021 cagccgatat aaaagctgaa tgtttatttt taaaagaaaa gggaattgat tcaaagtccg
     4081 atcagggctt ttctttctcg cttaaaaaag aacatatgtt cgaaagggtg tattcaattg
     4141 ggcgattttt taacacatct tgaggaatac gtcaaaaact tatattgccg catgggaatg
     4201 accgcccctc tccatattga tatgcagatg attgccaagg agcttgacat ttggattcat
     4261 tttgaagata cgcacagtat gatgctgaag cgggacggca tgtacagcat cgtcctgaat
     4321 caaaaaaagt cacccgaaga gcaatggcag gattttgcgc acgaactgtg ccatgtgctg
     4381 aagcataccg ggaaccattt tcatatgaac aagctgttca gggaactgca ggaatttcag
     4441 gccaaccatt ttatgtacca cttctgtgtg ccgaccttta tgctgttaaa catggagctg
     4501 ccccagcgga ggagccacgc cgttatttta atcgcagccg ctttccgggt gacggcatca
     4561 tttgcggaaa aaaggctcga gctgtttgaa cggcgtaaag caggtattca atttcagaag
     4621 cggctcgctt gtctgttatc cgacaagcgg ccgaatgtgt attatggaag cggacagaca
     4681 cacttgcatg ccgctgaaga aaaaacgccg tattttattg aaaattagcg attctccgcc
     4741 ggctttgaac acagccggca gaatgtcatc attttgacat cggagaaaag gtttttgcat
     4801 catgacgctg taatcaccgt gctgcccgcc aagcacttca tgcgccgcct agctccagtg
     4861 aatgtaagaa cgggccccct gttcatttat cataaaaacc ggccttcacg gtttctacat
     4921 accgaaaaaa cagatcggtt ggcgtatatt tttctccccg gcagccaaaa ttgctgaaca
     4981 gcgcgtgtct ctgcgccgtg ctcacttcca attgcagccc cattttcctt tttgtccgat
     5041 tgacaatgtt gccgggattt acacctgcca gccgatcatt cttctctgtc agctcggcat
     5101 caaatcccgc ttcacgcagc agatcacaaa tcagtcttgc tttttccaga tccgcgcccc
     5161 cgacgagtgt atttgccttt ttcagatcat gatacccgtg aaaagccaat gcgtaatgat
     5221 gggcggtcac tttttctaaa gccagaggct cgtcaaagcg tgtgcttgtc aagtggagag
     5281 aacggttatc gcaccgcttc gtcccttcaa ataaataaat tgagctttgg tcagaaaatg
     5341 cctgcaccag ctcactgaca cccggctcaa ttctgccgcc gtggggagcg aggacgatac
     5401 atttacttcc ctctttttct tcataaataa ttctgtattc cgattcagca gcggaaaggg
     5461 ctgcgaaatt gtcatatcta tctttcatgt gtaacatgct ctccttttcc agtcagcacc
     5521 agtttactct actcatctgg gaatggaaac ctttttatag tatgatttga tagaatacgt
     5581 atcagggagg agatatcatg gggttcatca atggattgct gggcaatgcg tcgacaatat
     5641 cgacggctga agcaaaatca gaactggccc gtattttgct ggaaggcgag aatgtcaatg
     5701 ccacatttaa gcttgtccga gatatcattg tctttacgga taagcgtctt attcttgttg
     5761 ataaacaggg actcacgggg aagaaaacgg agattcaatc cattccgtac aagagcattt
     5821 ccagattcag cgtagaaacc gccggccgct ttgaccttga ttcagagctg aaaatttgga
     5881 tttcaggcgc ggaacttccc gctgtctcaa agcagtttaa aaaagatgaa agcatttatg
     5941 atattcaaaa ggcccttgcc gcagtttgta tgtaagaaga aacggaagcc cgtggagctt
     6001 ccgttttctt gattacagtt tttcttcaat tttcgccttc gttttcgggc cgtaaattcc
     6061 gtctgccgtt aatccgctga cggattgaaa acgttttacg gcatatgccg ttttcgggcc
     6121 gtaaacgccg tccgccccat gattttttgc tcctttatcg ggataaaaat aaagagcgga
     6181 taaagcgttt tgcacttgtt ttacgtttgt ccctttcgtc agcggtttcg tcactttgat
     6241 tacaccggat ggaagcggat aggaagacac agcctgactt tttgaagaag aacccgtctg
     6301 agcgagcttg atcacttgtc cgactgtaat gtgattcgga tcggtgatat ggttgatgct
     6361 ttgcagtgat tttacgctga caccgtgcga tgcggcgatt tccgataagg tgtcgccttt
     6421 tttcacatgg tattcagacg cggaagaaga aatagaggct tttttcgccg gcatacttcc
     6481 gcttaatttc ttttcaatct tcgccttcac ttcatcccag cggccttcag acaaaatacg
     6541 gtgcgggcag tactttccgt tccagtcctg atgctttctg attctgtcaa tcccccagcc
     6601 ccgttctttc aaaagctgcg ccgcaaacgc aatcgccagt tcttctgcgg ctctgtaccg
     6661 ttcgccgcct gacttgctgt aacagatttc tatagcaatc gactttcggt ttccggtgcc
     6721 gttcgtgccg tctcccgaat gccaggcatt ccggtccaac ggaattccct ggatcacttc
     6781 tttgtcatca accgcaaaat gatagctcgt tgattcgctg tttcccgtca tatagctgat
     6841 ttcattagcg gcggatgcgt cgtttgccgt gttatgaatg gtaatatact ccggcgtcat
     6901 cggattcgga cattttaacg catatttatc agccgatacg agccgttttt tcacttcaat
     6961 ccccactctt catctctcct tatgcctttt tcatcaatag gtggcattcg taggacagat
     7021 aacttgagca tatcgaccct gcattcggat aaaattggaa tggatacgca tgcaaaaaat
     7081 aagacccttc caaagaaggg tctttatgtt atgtttggtt gcgtgcggca atatggaacg
     7141 tgccgtccgc ttggttttcc aaatggcttt catggccgat cacctgtgta aagctgaacc
     7201 ccacagcaac tagcagcaat cctgacaaca gtttagattt catatagaca atctcctctc
     7261 tggatttgtt tttgggcgtg caccattttt tcataaaacg tgagcgcttt ttcaggctgt
     7321 ccgtgtttca tgtaaaattt ggcagcgtca tgcgccaatt cttccacata cggatacagc
     7381 atgtgttctt ccagaaaatc aaacgtgtgc ctgacggatg cgttatccat ttccttgccg
     7441 tataacgcat gcaaaaattg gaacagattg acaaacaatt catcattgta ttcgcgggcg
     7501 atactgagcc cgaggcgata ttgcttctct gcttcggctg tagtgttctg tttataaaga
     7561 acctgtgtta atgagtaaat agaatgcgga agattatcga acttttctga cctgcaaatg
     7621 gaaacggatg tctcaaaata ttcggctgct ttagagaggt ctcccatttt ttcgtaacag
     7681 tttccgagat tatataaggc tgaactgata agacggggat tgccttcttg ttttgcaaga
     7741 tctaaagcaa gttctaagtg gggcaatgct ctttctggat actgcatgtc atcataattc
     7801 cctgcaataa cgaattcaca ttggattctg cggacgttgt acgtctcata cgattggtac
     7861 gtttcaaggg cttgaacggc ataactcatg gagacgtagg tttgtttcag gttgtaaaaa
     7921 atctcggcca ttttaaaagc aaactcagct ttctcgatgt catcagaaac gagtgcaagg
     7981 tttttttcag cccgtttgta atacatcatg gcgtttagga acattttctg tttaaattcg
     8041 tacattcctc gaaaaaaatt aaagtagtaa tcaagcagtc ctgtcagttt atactggttg
     8101 ccttcaatgt cttccaataa ttctgaaaac tcaggctgag aagggtcctc ctttaagggc
     8161 ttgatgtaat ccagcatgac gcggtgtctg aattccatta atgaataata cagcagcaga
     8221 tcctgatctt cttccatatc ctcaatctct ctctctactt cacgtttgac gcgctccgcc
     8281 tcaaggacgt gaaactgccg gatatgggta taccattcat taattttgag cccgacaaaa
     8341 gaggacggaa tagtctgctt catcctcaat aaatcccccc ttttggaatg accgagatat
     8401 gtcatatttt atcataattg ctagaaaaag aagaacgcaa aaagaccgca attgtcgaat
     8461 ttcggatatc cgcaacgatt tatctccatc acaagcttat tgcttgtttc ttccgtgccg
     8521 ttgatatagc atatccttgc agcttttatt ctgtattaaa tgggggtttt cacatgacag
     8581 cacaaaatca attggtcagc cactttctgt cacatcgaaa cgtgacgatt gagctggcgg
     8641 aaaaaatcag ccgtgagcat tacgactaca agccggcaga gacatcaatg tccgctcagg
     8701 aacttgtaaa acacatcgtt tattcttttc ttatgtttgc aaacgtcatt aacgacggaa
     8761 acgggtcagc tatccagaac aaaccgaaag aagaagcgga aacagacctc gtcaaactgg
     8821 ctgaagcatg tactgaaaaa acgacagaca tcctgtcaca gctgactgaa gagcagctga
     8881 accgcgaaat tgacctgact gcctctttcg gcagaaaaat aaccggcgcg gctctccttc
     8941 agcttgccat ggagcatgaa attcatcata aaggcaatct tttcgtgtat gtcagagaaa
     9001 tgggccacac ggaacttccg ttttatcagc aaaaatcata atccggccat catccgccga
     9061 tctgcgaaat aacagcaggc aggcggattt ttttgttctg cataaaattt tccgaaaatt
     9121 taattgatta ctgcctctta atcatatata atctgataaa aatagtagga ttattcagga
     9181 ggcacacaga tgactgtaag cattgtgttt atgggtttct ttgtcggaac gctggtcgga
     9241 ttgacgggtg tggggggagc ggcgcttttg actcctttac tgatcgtttt ggggatcaac
     9301 ccctcaatcg ccgtcggcac tgacctttta tataactcca tcaccaaact gttcggtgtc
     9361 gtttctcatt ggaagcagcg caccgttcaa tttaaacttg tcggctactt ggcgctcggg
     9421 agcattccca gcgcaacagc cgccatcggt attcttcact tgtttcccgc ttttcaccag
     9481 catcaggagc agattatcaa acaggcgctc ggctacgtgc tgacccttgt cgccatttcc
     9541 attatcgccc gccttttttt cgataaaaaa ctgcggccga accgctggca gcaaaaaaca
     9601 cttgaagaaa agcggacact catgatactg atcggcgtca ttttcggctt catcgtcggc
     9661 ctgacatcta ttgggtccgg ctcattattt gcgatcgcca tgttatacct gttcagaatg
     9721 aaaacagcag aagtggtggg aacggatatc gcacatgcct ttttgctcgt aactgttgcc
     9781 ggtctgttaa acgcaagctt cggaagcgtc gattacctgc ttgtattgaa tctgttgatc
     9841 ggctctgtgc cgggtgtgct tctcggcagc ttcttttcgc cgaaattctc accgcgcccg
     9901 ctgcagtttg tgatggcggc gattatttta atcagcggga taaaattaat ctaaaaaaag
     9961 cgtcctttac aggatcgctt ttttatttgg gaaatccccc tcaatccaaa gccaatgggg
    10021 tgggaatttc tttattaact aaccttaaga gtgcatataa ttgtccggtt ttccctaaca
    10081 tcataccaag tcccgaatga tcatttctta ttccattttg ccagccattt ttcaacaggg
    10141 tctctttaaa atggttaacc catatattaa ttgtattctc aatctcttgc ttgcgatttt
    10201 taaagagaga taattcctta atagcgtgaa gtacatctat attccccatc gttccatggc
    10261 ataatgagta gccctgacga tgggaatttc cattcagcaa tgtgtcatct aaagactcat
    10321 taatataccc aacgtgaatg cgcccgtcta cattctcgta tatcctgctt cttccaagaa
    10381 gaataccgca agacccgtga caccacattg cggaagaata atccgactca ttttttctgt
    10441 tatccctcca tttttttatt ttagtatcaa aaaatttatc ttcgtatttg agagctgatt
    10501 caatcagtct aagtacttct ccagatgcct caatatgcgc ataatattca gatagtgcat
    10561 aacaaatccc agtaataccg tgagaaaacc ctgctaaaac aacattctca tccgcgtcgg
    10621 atttccaata tgcttcattt ctattttgaa tcattctttt gcatatttct ttacaaactg
    10681 cccttgccgt atcttccatt aattcagtcc gataatacct gccaagctga atcacaacct
    10741 ttaatatacc tgcgagtccg cctataaaat cggtatgtgt tatttgagcg gtttcctgac
    10801 gaagtttctc taagtatgct ttacacatac tattcacttc attttccgaa taaagtccgg
    10861 tacctctcat tttattgaca aaatagatat aagaacttga cccgtaaaaa gcagagaaat
    10921 ttgttttata aatactatgc tcatatattt gattaattga attcactatt ttacgaagaa
    10981 tcgatttgac tttttcatca ttataattaa aatcataagc tgaaaaataa agccccactc
    11041 cagctaaccc atcgtacagc ccaaaactca acggtcctac ggataaggtg ccattgggag
    11101 ccgagactat tgatacccat tgaagatatt tctccgattc gattgcttgt tttaatatac
    11161 aatctgtttc tatttgaatc agctctttga tttgtatgtc attttttaaa tatccaggta
    11221 caaaatcatc aatttgattt ttataaataa tatccaaatt agccgccgtg gagcttaagg
    11281 ccatatttat caagctcact tgctgatgca tgtcttcttc cgacatattc gctaaacgag
    11341 ttaaaacttc ttgtttagcg ctttgtttca taatccctgt atccaccaca tgtattgaat
    11401 ttgaataaac ccttttttca ctaataggag cattaaaata gggtatatca ccgatcatca
    11461 tatccttgat ctcaaatgga ctgatggaat caaatacttc atattttgta taagcatcct
    11521 taataaaaga taaaaccctt atcctttctc cataatcttt taaatacata gggtggagga
    11581 gggtttcaag aaatgaagcg taaacatatg taggtctgac aataattcta ataggggcat
    11641 aatttaattc gcttataagg ttccgtatat ataaatcttc tttcaaaatc aagaatattc
    11701 ttttgaagcc ttcaataaat tctctttcaa attcaaaaca ttctgctact ttatttttgt
    11761 aaacaggaag attccttccc cttttgaaga gatattgttt ctttcttata gaaattttat
    11821 ctgtttttat atgaagcact tcttcttttt cacctttttg attttctgtg tttatcaagc
    11881 ctcctatatt agtcagccca ttatcttccg gaaaactcat atagttaaaa agtgcagatt
    11941 ttaatattgt tttatttacc tgtgctgatg ccattaaatt aacattttcc ttgttctcct
    12001 cagaaaaaaa gaggctgctt tgaaacagag tctcaagatc aaccaacact ggtttatcac
    12061 gacatgctat gatattttca aaatgaaaat ctgacccttg aaaagcataa ataaatccta
    12121 aatgcattcc aaattggtaa taataatttc ttacctgttc aatattatcg cacggttcag
    12181 actgtacata ctcttgccac ccgtactcac cttgatccaa ggataaaggt gtttttaaat
    12241 tagtttgata atactgattg acataatcaa tgaccttttc ataaaaaaca tcaatttcaa
    12301 gtgaacgggg tttataaacg agtttgttat tctcaaattc aataataaca acacttttac
    12361 cgccattatg aacatcccct gcattcatat taacctttct catttttccg aacgaaaagt
    12421 tgaatttttg ttggattttt ttatagtcat taacccaatg tttaataata gatatagtga
    12481 agcgtataaa atcagaggtg gatctggaga ttaaatcttg caatacagga taattattga
    12541 gtatttcttc aacaaatgcg gagtttttca gcctttctga gaatatatca taatttttag
    12601 attcattttt ttcatcaaac tcgtcaaaag tttgatgaaa ctcatggata agtgttttcc
    12661 ccgccaaata gtatattttt ttcttataat taattaatat cgattcaaca agacatccct
    12721 tatccaacag actttcggat ggtattctat ctatttcttt aacaatctga gctttaaaaa
    12781 tacttatata atactgcgca aaaccttcga aataatcctc ttctttaaaa atattcaaca
    12841 tagagttttc ataaacatag ttagccgaat tctgtgtttt gttcacaatt atcacttcct
    12901 tatatattct tgactgtctt tgacaaaaaa gaaaaagaat atgtacgcat atacatattc
    12961 tttttcggat atgtttaatc gttacatgga ctgacaatgg acgcacactt tgtcgtcgga
    13021 cagcctgcta aagagattgg tattgtgatg gttgtcggcg ttacggtcat cggggttgca
    13081 tctgaacccc ctgcaaggtt ttttaattct tcttcagtca ttggagtcag tgcttgaaaa
    13141 tcttttttca tgttaattcc tcctattgtt tgagtttttt ataaatttca gtcgttacat
    13201 ggactgacaa tagacgcaca tttagttgtc ggacagcctg ctaaagagat tggtattgtg
    13261 atggttgtcg gtgttacagt cattggagtt gcctccgagc cccccgccaa ttcttttaat
    13321 tcttcctcag tcattagttc caatgctaaa aattcttttt tcattaaaaa tccccccgat
    13381 tgttttttat acttgccttt gcggacatgc gcagcctact gtgatagttg gacaaacatg
    13441 atttgttatt ggaattgttg ttattgatac tgagttttgc cctccaataa gctctcttaa
    13501 ttcttgctct gatgtttcat acaacgcgct gaagttctct ttcatattcc atatttcacc
    13561 tcctttcaag ttaataagtc tgctggagct gtgattcata tttggtctta atcgtcttta
    13621 agtttccatt ttcaatctcg tagacagatt cggagaattc gagccattcg gttctatgag
    13681 taatagaaat tacagtgata tcctttttgt aaatgttatt taatatattt aattctgtat
    13741 ccttatccaa attgcttgtt ccttcatcta taaatagaat tcgcggattt ttcgctaata
    13801 ctctggctat tgagattctc tgccgctgtc cacctgataa ggtaatacca ttttctccaa
    13861 tcatggtatg ataccccata ggcattttta taatatcctc atgaatacat gcttcttttg
    13921 cagcttgtac aacttcttcc attgttattt tttcattgaa atattttata ttatttataa
    13981 tagtgtcatt aaacagattg acatcttgaa caatataacc taacgtttct ctcagcttaa
    14041 ccatattaac gtcctcgatt ttgaattcac cgtagcaaat ttctcctgct gttttttgat
    14101 aaaggccggc aatgatttta atcaaagtag actttccgct tccggttttt ccaattaatg
    14161 tgattttttc tctcggacgg atcattaaat ttatattatt caaaatataa tcgtttccgt
    14221 tgtagctgaa atcaatattt ttcaagctga tattatgagc ggccgggtta aatagttcaa
    14281 tgcttttatc atttatttcc tcatcttttt catccagtac agcctcaacc ctgtctacca
    14341 tttcttcaac taatttaata gactctaaac tgccgataat tgatcccagc ggagacataa
    14401 accgtccggc aatgttagaa aaagcaatta ctgcgcctag cgtaaggcct atagatactg
    14461 ctgaccaagt acccacaatt aaaataagta atggcaaaga tagattgatt gcattggaga
    14521 ccgcacccag taaagatgaa taattcattc ttttagagaa ataatctaac tgatgattaa
    14581 agttataatt taattggctc tcaatattcc tggtttctcc tattgttttt ataaatgtca
    14641 ttgatcttaa gatttcgatt agctggctct gaaaattgga ttgactattt acttcctgtt
    14701 ttgtgaacat ttcaattttc ggaagcaaaa ttttagtact catcacctgt atagctgctc
    14761 ccaataaaac tataaaagat aatatcggag aataaacaaa catgactatg aaaaatacaa
    14821 atataagact gatatctaat atcaaagtag acgctaacct ggaaatgact tcacgaatta
    14881 cagcaatgtt atggattcta gttgaaatat ccccggcagt attcgcctca aaaaacttta
    14941 atggaagact aaatatttta tgaattattt tatcagtcat actcttatta atttttaatt
    15001 gcagtttgat aataaatttc attctgatta aggacagact aaagaataat acgattgaaa
    15061 caattacaat catgaaaagc attggtatgg gaagaatttt ctcatttccg tcaataaatg
    15121 aatcaataat atattgagtc aaaaaagggg tcattaagtt taatgcttga aaaataaaag
    15181 tgaaacttat aataaccccc aacaattttt tatctttcaa aagatatttt ccgatctttc
    15241 taaatgaaga cacatctttt aacgacgaag cagtcttatc ctttctctca agttcgttct
    15301 ttctgattaa cataatagaa atgccattat agaaggtttt gaactcttct aatgtgattg
    15361 tcagtctgcc agacgaaggg tctataattt taacgttatc tgtgccaaat gcgtcgacaa
    15421 ctacaaaatg attatgattc caatgaacaa ttagcggatg gtttttattt aactctttaa
    15481 gctgcgttat attgtctgtg cggaaagctt tgaaatcata atcgaatgtt tcagaaatcc
    15541 ttttcatttc tattaaatca gtgccgtctc ttccgataat ttctttattt aatttcaatt
    15601 tgttaggatt gatttttatt ccctcagccc tgctcaaaac catggctaaa caagtaatac
    15661 cgcaatcaaa ttgatttctt tgaagaataa ccggaagctt tctttttcta attttcataa
    15721 atgtctccta atgtatctac acgtcctatt tcaagattga gaatattcgg caattctgcg
    15781 tctgctgcat acagcattcc atatacgatc cccgctaaac caagcattaa attaggtgtt
    15841 tcaacatccc ttccaactcc gcattggtag aaacctatat ttttgtcttg tacactctcc
    15901 aaaatcaagt tttttcctat atttacaaat tgactttcac cagtcttttt tccatattcg
    15961 atcagtatta aagcatttcc catgtctccg tgacaaagac tttgctctcg gccaaaaccg
    16021 tcataaaaaa tgttagaaac ggttttattc agatcttttt tggccacttc ggcaatatca
    16081 gggtgttttg aatctttcaa ttctaatctg cttaatagaa ttccagggga tccatggcac
    16141 catgcagatg ttgcagcttc atttaccgtt tttctcagat caagccagtt accgtttact
    16201 ttttttgaat tttcaaaagc aagtcctttt cggatgtaca tacttatatc ttgatgtttt
    16261 gaatgtttct cgagtaattg aagggcatat atcattccag cgtttccatg ggaaaaaccc
    16321 gttaacggct tatttgcaat accttcccaa gtgacaaaat cctcatcaag aaagatcgct
    16381 tgtttcatta aaaatgaacc gcattgttca gccaatgata aaaagaatgt atcattctct
    16441 atttcaaacg aacgtatcat tacaataaga gcccctgctg tgcccccgat tatatccaat
    16501 tctttatcat aaggaagcaa ggacggaata agctgagcga tttgttttgc attctgttta
    16561 tatttttcgc gtttagtata catatagaaa ttcattaaag tatatactat tgaagacact
    16621 ccggaaaaag cacctacaga catactgctg tcttcgtccg gtttcacctc aatatcaata
    16681 aaacgagaga tgacatcttt cataattttt tcggcaatgt ccagatactt ttcttttttc
    16741 gtgacgcgcc ataaagccag gtaggtgaaa gccatcccgg aaagcccgtc gtaaaaggta
    16801 tcacccataa cggataagtt ccattgaatt tcatcaactc caataggagt agcgttaagc
    16861 caagaatacg aacttccttt atctgtgtgt gctttgtaag attgattata aatataagcg
    16921 gccaattcct ctgctttttc tattaagata ctttcttggt tactactgaa aacatttaca
    16981 tattgtcctg gttcttttgt tataaattct ttcaaaacaa tttgccgatc atcctccgaa
    17041 gcaagcattg acagttcgat aacatagagc tgaaacttta aatcgtcttt tgataaattt
    17101 gaaattcttt cttttacact ttgagctggt gtttccggaa agtaattttc aattttctta
    17161 ttttttgagc ttagtaagtc tttctcattc aatttcactt tgaaataagg tatatcatta
    17221 ttaattaaat cgttgaactc atatttaaca atagattgat attcatcttc ttgctttggt
    17281 ctctcccata tttttgataa gaaaatttct ctatcaatag agttgtgtaa aaatctagga
    17341 tgaaaactta attctaataa agcagaatac tttattgtcg gttttgatat aaaccgaaca
    17401 tatatcttgt tttcgctctt ttctattatg cgaatcagct ccgaagcatg ttttaatata
    17461 gtcatatatg cttttgaaaa accttgcttc agttcttcga cataatcttt tgcatataca
    17521 aatttattct caagcatagg gtgattatta gctgtatcaa tttcgacata gtctcgtttg
    17581 acagacattt ctgctgtctt taaattgata agctgaggaa ctttaatgat cgactttgct
    17641 ttccctttcc gacctattcc gctgatgtcg gctttgcccg caaagaagaa aggaagcagc
    17701 cctaatgctc tgacagattc atgaagctgc gtttcagctt tttcataagc gtccatccca
    17761 tccttttttt tctggtatgc aggatgaaat aaggattcca aatcaatgag aactggatag
    17821 ctgccgttgg caatgagatt ttccgaatga aaatcaacag ctttcaatgc atataacaaa
    17881 ccgatttgag ctcctgtacg ctgataaaag ttttgaacat cttttaaaca attgcatgct
    17941 ttaaaagata taaattcagt ccatccatat ccgtctctgc taaggacatt cggagtgctc
    18001 aattttatat catgatctct aattttctca ttcaaaaatt caattatctt tttatataat
    18061 agatcaattt ctaaacttct cggcttataa ataagtttac cttcatttaa tgttatttta
    18121 gtaacctttc tcccatcaga atgagaatca cccatcccta cttcaatgtc ccttattttg
    18181 acttgttctg aaaaaccaaa taaagagagc agttcaggct tgtccttttc aaaacgggag
    18241 ataaattcca gtatgaattt tttaaatttt ctcagttcat ttccaatcac tcttaataag
    18301 actggatatc gttggaaaaa gatttcaaga tactcctgac tgcacaaaag agttttatta
    18361 taatcaccat atttttcttt aggagtctcc cctgccaaaa aacctttttc ccgattcata
    18421 ttcatatcca atacaagtgt tctataggat acttttaaaa tgattttttc taattgattt
    18481 gaaatactat gatgaaaaag agccggttgt tccagcagat agtcataaga aggaaacttt
    18541 gattttttaa gtagatcatt gaagtaagag gacactttta acgcaaaaac gtgaaacatg
    18601 atttcttcat ttacgtcttc ttttttaata gcttggtgag cgatcccttt ttttaggttt
    18661 tcgaaaacat gaactgtaaa agcggattta tgtagtgggg tttgatataa gcttttcact
    18721 ttatcaattg attgaatgga taacacatta taaatgcttt cctgggccat ttgaatatca
    18781 ttcttataga ttagttctaa gtttcgatca aacagtttct cattttcatc aaattgagag
    18841 acagcagctt ttttttcttt acttaataga atattagtta gcgaattcat ttaatattca
    18901 tctcctttaa aaaaagaggg agacagctgg atctcccaga gcattggaaa tctattttct
    18961 tatttcgggt tgttttaaca ccagcaagtg tgagtaggac aaagaccgca ttcccaagtt
    19021 aacgtacaaa gcttaccatc atttccttga gaaatccccc gctgttctgc gcctcctcct
    19081 ccgctgaatt cacttaaaga aatttcctca agttcttctc ttaaatcacc ggcaaaacga
    19141 tacattttct cattcattaa tattcctccc cttgattttt gaaatatatt ggattttgat
    19201 ccatatattt ctataaacct atgataaacg atcttttacc tataggcacc gaaaagtcat
    19261 attcggaaaa gcgctttttt tttgcgcgtt tccgaagtat aggttataaa gaaaatcggg
    19321 attaactctt ccgttaatcc cgattcattt actcatatat agttttcata gaaattaatg
    19381 aatatcgatt tgctttgatc agtgcctctg ttctggattt tactccgagc ttgttgtaca
    19441 caccagtaag aatgtattca accgctcttt gactgatcaa aagctttgct gataattccc
    19501 ggtttgtcat tccctccgct acgcccgcta agatatcttg ttctctttca tttaaagtaa
    19561 tatctcttat tctatcttca agcttatcaa tgttgaacgt atttgcttct gttcttctta
    19621 attgtttaaa gagatgagta ggaataatgg tatctccctc aatgacactt tcaattactt
    19681 ttatcatatg ttcttctgtt gatgacttac ttatgaaccc ggaaacacca acttcaacca
    19741 aaagattgaa atgcacagag atatcaaaac cagtataaat tataattttt tgatcggggc
    19801 tctctctaag aatcattttt gacaattcca ttccatttaa ctccggcata tataaatcaa
    19861 gtaaaattaa gtcatactca taatgcttaa ggtgattaag tacttcttta cagcaagaca
    19921 atattgttac tcccatttta ttgctttttt caaggatggc ttttgtccct tgagcaacac
    19981 caatatgatc atcaattaat agaatcttta tcatgtcagc gctccctatt catttttcgt
    20041 acttatttca aaccttaaca gcaatccttc atttacgctt gaagatatat tatgaatacc
    20101 attcatacaa tttatccgct cttttatccc tgtcagccca aaactgtttg tttttgaatt
    20161 tactttattc caatcaatgc cgattccatt atcttcgtaa acaaacataa gacttgtttt
    20221 tttttgaatc atcgtcaaaa caatataact ggcttttgaa tgttttacag cattagtaag
    20281 cagttcttga acaatccggt aaatgtttat tgtgatatct tctgtaaaaa tagaatcatc
    20341 ttttacatct acaaagaatt caatatcaag ctgatagttg cttttatgtt tatcaatcag
    20401 gacttgaatg cttcgaagaa gtcccatctc cattaaaaaa ggtggtctta aatcaaaaca
    20461 tttttctctt atatactgga tattgtccag caaaatttct cttatgtaat aaatatcctt
    20521 gtatttctca acatgatact ctaattctct gcatacaaat atcagctctt gaatgataga
    20581 gtcatgaata tcctgtgcaa gcttggttct ctctatttct gaaattgaaa ataaaacctt
    20641 agaaagtaca gccgacttac atttatgttg atcgtctatg ataatttcat caattttttt
    20701 ttgaatcaat aatttgttct gaagtgcaga tgctgtgcag aatgccagca ttcgcagcca
    20761 atctgcctcg ttttcacgaa tctttatagg gtgtcctcca tgtgataaat gaataaaaac
    20821 aaatgtatca cacttctccc cgataaacag aattgatccg ctggcggttt cacgtatttc
    20881 tcctatctta aaatttgaaa tgtttatgtt aggaacttga atgttttttt ctttcaattt
    20941 taatgttttt ttgtcatagt ttataagagc aatctgcttt cctgagagca cactctgtat
    21001 ttcattggtt agttctttta tcaattgatc tgcatcggat ccctcttgac ataattctga
    21061 aaaacggaac aggctgcgaa gatatgtctt atttctgtca tcataggtaa agcataaaca
    21121 actactgccg aatatactta gaacaaaaaa tagactatac tgtttaaact gtaattggct
    21181 gtctgttata agcaaaagca taaaaaacaa taataaggag aaaacaaaag cccttgcaaa
    21241 ctgctcaata ttaagcttca cccaattatc tttcatttgt atccaagccc cttactaagg
    21301 aaaataaggg aatccctttg aatcccctta aaatgaaaaa gttactttac acttattaaa
    21361 atataaacag caaaggcaac aatgtatacc agaaatgatc cagtcataaa ttttacaggt
    21421 tttcttgaaa agtttagtac gcctcttaat ccgtcattca aaatcattcc gaaaaaggta
    21481 accagtgtaa ctcctaaagc gagcattgaa atcacaaaaa taacttgctc catgtatact
    21541 catcctccat ttacattctg ttttttttcg aatatacgta taatcctgat aaggatacca
    21601 aaacatacag ccccataatc agtaatcccc aaactaaaag aattgaattg gtatatccca
    21661 tatcactttc aaaaatttga atactgaaac gataaataaa agaaaaagga aagactattg
    21721 agacatcact tgctaacagt atcgtcatta ttaaaaagga agctacaccg gttatcatga
    21781 caaccactag atttttactt aagaaagcaa ttaaagctgc aatcggaata gttagcaggc
    21841 tcaaagtagt agaagtaaaa gatgtcgcta ttaatcttaa taagtcgctt gctgagatat
    21901 cttcccgaaa aaagaaaaac aaggtggata agtgaataat atgattaaca gctgagatta
    21961 aaaacaaaaa tagaaaagct gcagctagct ttgataatat caatttgaat ttatgatacg
    22021 gatatgacat ccaattcaac attgtcctgt ttttaaattc taaataaaaa taaaaacctg
    22081 aaaaaataaa aataatagtc ggaaatagga tcgaatactg attaaaaaca aacatataaa
    22141 atttgttcca atctgtattt tcgttcatag tcaaaagacc gattccgttt atgagaaatg
    22201 gcaaaaagct tagaaagaaa ataacataaa ttgatttcag tcttttaagt ttcagaaact
    22261 cgttacgcac taacagactc atgacctttc tcctttgcca gcagttttaa ataaagatct
    22321 tccaaagata gcttaaatcc gtcaatagac gccttgttaa atccccaaga atttaatttc
    22381 tctttcattt ccgacggatg aattattgaa ataaactcga attgctgttt attctttgaa
    22441 ataacatgat ccgcaaattt ctcaatatcc gcccaattaa tacccgcttc agctggaatt
    22501 ttgtacaaat aaagatgttg cgtatttttc ataaaggctg actcgaaaat aatctgcccc
    22561 ttattcataa taagcaattc atcggccatg agattaatct cacttaaaag gtgacttgaa
    22621 ataacgactg tggttccatt tttcattacc tcttggatca acatttcacg tacttcttta
    22681 ataccatatg gatctaaacc gttcgtcggc tcatccagca aaagcaatgc aggagcatgc
    22741 gcaactgctc tggcaattcc cagcctctgt ttcattccta atgaagtttg cgaaaacagc
    22801 ttatctttat gttcaaaaag tccaaccttt cctaaaatct catttatttc ttcatcagaa
    22861 gctgattttt ttaaatagtt aagatgtaat ttaatattct caaaaagatt caaattttca
    22921 taaaagccag gaaattctat aatgcttcct atagactgaa tcacatcatt atttggattt
    22981 tcatataagt cattctcctc aaaaatcact tcacctgaag ttggaggaaa tatccctaaa
    23041 agaactttaa gcaatgtcgt ttttcctgca ccgttgggac ctaataaacc atatatttta
    23101 cctttttcca atgttaaatt tatatcatgt aaaatttctt tcttttttat agaaacattg
    23161 atacccttgg atattaaagc tggatcagcc tttcccactt ttcatcattc ctctccgtct
    23221 tgttctgttt ataatataaa cttacgaggt taaaaagaag atatagtcaa ggttaattta
    23281 cgtttaaatt tctcaatata aaaaatacgt gaagcctcta cggcttcacg tattcattgc
    23341 tgtttggata aataataaaa accgttccgt tttgattgct ctttatttta tgttcaagcc
    23401 ccatttgttt aagcatcata ttaatgatcg ataagccgat cccggcgcct tttctttcag
    23461 atttataatt cattcccggg cccctatcct caattatgat tacgggtttg ttttcaatta
    23521 gctttgtctg tacggaaacg tattttcctg aatgagcatg gcgcaaaaca ttttgaaaaa
    23581 tgttatcaag aattctcttc agccaagtct cgtctatttc ccatacgatg ttttccttca
    23641 gatcaatatc tattgtgaag tgctctttct caaaaattgg ataccaagct gttaacgaag
    23701 aacgtattat ctttaatatg tcacaactct ttttatgaag cggcaattta cctgcggcaa
    23761 gaagagaaaa tgatgacaaa ttgtcaatca gttcgcccat aaacgttatt ttatcgttta
    23821 tgatgcctaa agaatgcttt ccattttcac tgcttatttc attcttcaac gtaaatgtat
    23881 gccctcttat aaccgtaaga ggggtcctta aatcatgaga taaatcagca atcaagtttt
    23941 ttcggatttc gccttcttca cgctcttttt gtctgctgtt ccttagttcc tcaaccatct
    24001 ggttgaatga atattccact tgacccagtt catccttctg tttaactgtt acaaattccg
    24061 gtatgccgtc attatcttgt tttttcatat gattccccaa agaaattaac cttttttgta
    24121 ttttcgcaaa aaacatccat gaattaatca caaaaagtga acagacaaaa atcaaggcga
    24181 taaaccatat ataggaatac ttggccctca taacctccca ttgagatcct ataattgagc
    24241 gcggagtttc taaaaatgca tatccgctgt cttcactccc atttacataa gcactcagca
    24301 ataaatattt cttttggttt tgttccatca atttaatcaa ttcgctaacg tgaataacct
    24361 cacccttttt ggccaaccgt tctgagttcg aaaacatcac ctttccctta tcatttatcc
    24421 atacaatatc agagtgttta tattgcttca tgtgcgggaa agcagacgta atttcccgat
    24481 tggatttccc tgaaaaacct tccacatcag acttccaatc actttccaac ttgtttggtt
    24541 catagtgtac ttgcccctgg tgatcaatca agtatgttaa tgtgacatag taaagaaaat
    24601 tcacacctaa aaaggctatc ggaaaaaaca aaattgaggc aacgatatta ataaggtatt
    24661 ttgttgataa tttcattgtt taatcctgta tccaatccct ctgatcgttt caagaatttc
    24721 cggctcattt ggattgatct cgattttttg ccgtaaatgc ctgatatgta ccatcaacgt
    24781 cttatcccct tcgatataag gctgctccca aatattttca taaatttgtt cctttgttaa
    24841 tatttgattg ggatgtctaa gcaaaagtaa aaaaatcctt aactgcttat cagttaaaaa
    24901 tatttcctca tgactttgat gatttaaaat tcttttttct ttcaagtgga cacttaagtg
    24961 ttttagcttc aattcatgaa tggcagtctt gtcaaatctt cttaataata cttcgattcg
    25021 agcggccagt tcatcgggat gaaagggttt tgtcacgtaa tcatccgcaa atcctaagcc
    25081 tttcagttta tcttccagac ccgttctcgc tgttaaaagc aagagcggga tctgcggatg
    25141 tgtttttttc atcctttgac cgattgtaaa tccatctaaa ccgggcatca ttatatcaag
    25201 cacgatcaga tcagcctttt ctatatatgt ttcgtaatta taggaagaag tgagccatat
    25261 aatcatatag ccccgatctt ctaaatcatc ctttacaaat tggccaattt cttggtcatc
    25321 ttcaatgtat aaaatgttat tcattaggac cccctctgaa atatgtgact aaaaaccaat
    25381 cttccataat aattatatat attataaaaa tctcctttat gtaaggcacc attccattat
    25441 tatagctcat agatattcac aattcatcaa ggggcaaaac gataagtgaa tgcgaaaagg
    25501 cggtctgttg tcagatcgcc ttttccctta taacgtcaca ccggacttaa agattgcaag
    25561 ctcccgaaaa tcgttttttt cgttattgac gtattgtccg cttgcaactt taataatgta
    25621 ttgaataaaa tctctcacaa tgtgatctac tgttgtttgg tcttccgcca atctgcccgc
    25681 attgtaatca atccaatgag gttttgattg aaataaatcg gtatttgttg atactttcac
    25741 agtcgggaca aatgtgccga acggcgtgcc tcttccggtt gtaaacaaca cgatgtgaca
    25801 gccagccgca gcgagcgctg aagaagcgat taaatcattg ccgggcgcac tgagcagtgt
    25861 caatcccttt gttttcagtg tttcaccgta tgtcagcaca tcagaaaccg gtgcaagacc
    25921 ggctttttgg gtgcagccga gcgacttgtc ttcgagcgtt gaaatgccgc cttccttatt
    25981 ccctggtgac gggttttcat aaatcggctg ctcgtgcttc ataaaatatt gcttgaaatc
    26041 attgatcaat cggactgttt tatgaaacac ttcttcactc accgcacgct gcatgagaat
    26101 cgtctcagcg ccgaacatct caggcacctc cgttaagacc gtgctccctc cctgtgcaat
    26161 caagtaatct gaaaatcttc ctaataaagg gtttgcggtg atgccggaaa aaccgtccga
    26221 cccgccgcat ttcaatccga tgctcaattc tgacagggga atctcctcac gtttatctcc
    26281 ctttgccgca aggtgtatct ctttaagaag cgctgtcccc gcttcaattt catctgtgac
    26341 agcctgtgat tcgagaaatt tcacccgatc tccgttcact tcagaaagcg tttccttaat
    26401 tgccgccagc tcattatttt cacagcccag ccctaaaacc agcacaccgc ccgcatttgg
    26461 atggcgaatg gcgttaatca gcatttgttt cgtattctca tgatcatcgc caagctggga
    26521 gcagccgtat tggtgcttta aaaccagcac attgtcaaag ggggcaatgt ctttcgcctc
    26581 ttttacgaag cgctgcagga ttttctcagc gacgccgttt acgcagccga ctgtaggcac
    26641 gatccacagt tcattccgga cgccggatgt accgttttct cttttgtagc ctttaaatgt
    26701 ccggttctca tttgtaaaag gattgtcctc gaagcgcggt gaatacgtgt attcttgcac
    26761 atcggataaa ttcgtttgca gattatgggt atgaatatgc tcgccggccg aaatccgcct
    26821 tgtcgcacgc ccgattgaaa aaccgtattt aatgatgctg ccgttttctt caatggtttg
    26881 cagcgcgatt ttatgccccc gctttacagg gtccttcact tcaatcgcca gtccgtctgt
    26941 atacagccgc tcccctttgt taaaatggcg catagcgaga agcacgttat cgtttttatg
    27001 gatttttatg acctctttca ttccacttcc cccttattgc cgcagcattc atgtaacgca
    27061 tgcttcatcc cccgcttatg aatgacagag agaaaaaaag cagttcgttc agtcagcccc
    27121 ggaagatggt tcagattctt tccccacaat cgctcttctc ctaatataga aaatgccgct
    27181 tgaaacatat catctttgca acgggaccgc gccatttgaa aacggttcag aacctcctcg
    27241 ccatctgccg gtttgttcag cccgttccag tatgaataga tcatggcgct gaatgaaaat
    27301 accagcctct caggaagccg gccctcctgt tcgatataag ccttcagcgt cggcaggttt
    27361 cttgttttga atttcgcggc ggcgttaagg gtgatgcttt gcagataatg ttggatataa
    27421 gggtttttaa accggtgtaa cacatctgcc gcatactggg tgacaccctc catttgcagc
    27481 acgggaagga tttcttcatt gatcagctct tcgatgaatc tgcccgtcac ctcgtgctca
    27541 gccgcttccc ggacggttag cagtccgtat aataaagcca ctggcgccaa tgccgtatga
    27601 gcgccgttta agattctcac cttttttgtc ctgtaaggcg taaggtcaga cgtgatcagt
    27661 gcgttcagcc cggcatcagc aaaaggaagc tcattctgaa gctgttccgg cccttctatc
    27721 acccacaaat aataatgctc accgaccaca agcagacggt cttcgtatcc gagaaaatcg
    27781 gtaagttctt ccgcggtatc aacaggaaat cccggaacaa tccgatccac gagggtattg
    27841 cagaagatgt tcgcatcatg aatccattga gtaaaatcag gctccagctc ccacagcccg
    27901 gcatattgaa gcacggcagc cttcagtttc cgtccgtttt cttcgaccag ttcacatgga
    27961 agcacaatgc accctttctc ggcgtcaccc gcaaatgcct tatagcggaa ataaaggaac
    28021 gccgctaatt tcccggggaa tgttttttga ggcctatcct caagccggtc gcctttctca
    28081 aacgtgattc ccgcttctgt cgtattggag atgataaaac gaagatcctc ttgtgctgcc
    28141 agccgtttaa aggaatcata gtcagaaaaa agatcaatgc cgcggctgat ggatttgaca
    28201 atcgtgtgtt cttcagccgg ttttccgtcc tttatcccct gcaaaaaaag cgtaaacaaa
    28261 ccgtcctgtt cgtttaaacg ttttattttc tcagagcctc tcggctgtac agcgacaacg
    28321 cttccgttaa aatccgtcaa ttgattcaat tgatcgatct gccaatctgc aaaggcccgc
    28381 aaaaagttgc cttcgccgaa ctgaaggact ttttcaggat attgaatgta ttcaccgcac
    28441 atctttttat tcagctgccg caagctgtcc gcctccttct gcatttatgc acacgttaac
    28501 atttttccgt acgaaaaccc ggatagtcag acgggccgtt atgtgagttt tttaattgaa
    28561 tctcttatca tcacctcggt gttttcgtat attttttccg ccgccgtatc cgggtcggtg
    28621 ataagcgcca aaattttctc tgcgccgagt atgctgattt tttcaaccgg gcgttttact
    28681 gtcgaaagcc tcggcgtcat gtattgggaa atgccgatgt catcaaaccc gataacggat
    28741 atatcttccg gaacgttcag gcctttggcg aaaatggtat tcatcgcccc gatcgccata
    28801 tcatcgtttg aacaaaaaac agccgtaggc ggtgattgaa gcgccaaaag tttttccatc
    28861 gcctgactgc cgctttccat atcatagcgg
//
