LOCUS       NZ_CP075054            20891 bp    DNA     circular CON 25-MAY-2024
DEFINITION  Bacillus velezensis strain VTX20 chromosome, complete genome.
ACCESSION   NZ_CP075054
VERSION     NZ_CP075054.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 3891321)
  AUTHORS   Vu,T.H.N., Nguyen,V.T., Bui,T.L., Quach,N.T. and Phi,Q.-T.
  TITLE     Probiotic bacterium Bacillus velezensis VTX20 capable of producing
            extracellular polysaccharides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3891321)
  AUTHORS   Vu,T.H.N., Nguyen,V.T., Bui,T.L., Quach,N.T. and Phi,Q.-T.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2021) VAST-Culture Collection of Microorganisms
            (www.vccm.vast.vn), Institute of Biotechnology, Vietnam Academy of
            Science and Technology (VAST), 18 Hoang Quoc Viet, Hanoi, Vietnam,
            Hanoi 100000, Viet Nam
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Link v. 7.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 197.0x
            Sequencing Technology :: PacBio RS II (Pacific Biosciences, Menlo
            Park, CA, USA)
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018415955.1-RS_2024_05_25
            Annotation Date                   :: 05/25/2024 04:39:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,861
            CDSs (total)                      :: 3,743
            Genes (coding)                    :: 3,682
            CDSs (with protein)               :: 3,682
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 37 of 61
            Pseudo Genes (incomplete)         :: 35 of 61
            Pseudo Genes (internal stop)      :: 14 of 61
            Pseudo Genes (multiple problems)  :: 22 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1513453
            Orig. end                         :: 1534344
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP075054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(428..443)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.59"
                     /tool="antismash"
     gene            515..721
                     /gene="spoIIIAC"
                     /locus_tag="KH277_RS07840"
                     /old_locus_tag="KH277_07840"
     CDS             515..721
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="KH277_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07840"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_003153142.1"
                     /transl_table=11
                     /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIYI
                     LFMVATIVDDLFKKIKAVFLFQG"
     gene            734..1123
                     /gene="spoIIIAD"
                     /locus_tag="KH277_RS07845"
                     /old_locus_tag="KH277_07845"
     CDS             734..1123
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007725724.1"
                     /locus_tag="KH277_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07845"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_071392571.1"
                     /transl_table=11
                     /translation="MEIVQIVGLGLIATFLSLIVKEQKPTFAFMIVVFSGCVIFLYLID
                     QIYDIIRMIEKIAVNANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKIELAG
                     KILILVMAVPILTVIIETILGLIPS"
     gene            1157..2365
                     /gene="spoIIIAE"
                     /locus_tag="KH277_RS07850"
                     /old_locus_tag="KH277_07850"
     CDS             1157..2365
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390319.2"
                     /locus_tag="KH277_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07850"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_003153145.1"
                     /transl_table=11
                     /translation="MKRFRWAGAFLFILLFFQTECVQAAGTDGASQETAVHQESADEVA
                     KKQAEALKTEGIGKFWDDIMTEYGGLLPESQKGSIIDFINGEKTFSPEAWLKALFSYLF
                     HEVLANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYAIVYMVLIILALNSFHVAV
                     NYASEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPL
                     IFLSAILSIVSTMTDQYKVTQLANLLRNIAIGALAVFLTVFLGVISVQGASAAVTDGIT
                     LRTAKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVGILICISAFPAIKVLSL
                     AFIYKLAAAILQPLGGGPVITCLGVISRSVLYIFAALAIVSLMFFLSITVIITAGNLTM
                     MMK"
     gene            2382..3002
                     /gene="spoIIIAF"
                     /locus_tag="KH277_RS07855"
                     /old_locus_tag="KH277_07855"
     CDS             2382..3002
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390318.1"
                     /locus_tag="KH277_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07855"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_003153146.1"
                     /transl_table=11
                     /translation="MSFLTEWLTSIILFILFAIVIDMLLPSSSMQKYAKMVVSLLLIIV
                     MLNPIFKLFKTDPEIIFDYLTKQEQSQSADIKNQIKSEKKEIQASNRAYVLEEMAVQLK
                     KKAEEMFSHDEYKIDDIRLTAEEQVRSEEDVKTISVYMAPSSEKTVQTVAPIDIRTDRK
                     YEPEGAADKKEAADIKEKLADIWEIGSEKITVYMEGGEKNGHE"
     gene            2995..3687
                     /gene="spoIIIAG"
                     /locus_tag="KH277_RS07860"
                     /old_locus_tag="KH277_07860"
     CDS             2995..3687
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390317.2"
                     /locus_tag="KH277_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07860"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_003153148.1"
                     /transl_table=11
                     /translation="MNKNGLWTILKKQLMIGQAKDGEKPKLTKYHYFLFVFVLGVSFML
                     VSQLFSSPEKTGKDQAAQTVMSGRTEDKSGQKSAPVFKASKDSSAKNTIDDYERDYENQ
                     LKEILETIIGVEDVSIVVNVDATSLKVFEKNKTKKDTTTEETDKEGGKRSVTDQTSEEQ
                     IVMIRNGDQETPVVVQTKKPDIRGVLVVAQGVDNVQIKKTIIDAVTRVLDVPSYRVAVA
                     PKKIKEDS"
     gene            3691..4341
                     /locus_tag="KH277_RS07865"
                     /old_locus_tag="KH277_07865"
     CDS             3691..4341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390316.2"
                     /locus_tag="KH277_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07865"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_139890052.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMKSEKSSGEVA
                     TEKTPAPETKDKNGSGTDKEDGTKGTKDSKGAKEDKETSAEASDKDGTVATETADENLF
                     TAYRMELEDARSKEREQLNSIVSSDDATAKEKSEAYDKMTALSNAEGTEKQLETLIKTQ
                     GYKDALVDAEGDKINITVMSDKHSNAKASAIIDLVEKEIKTMKDVAVTFEPTK"
     gene            4495..4974
                     /gene="accB"
                     /locus_tag="KH277_RS07870"
                     /old_locus_tag="KH277_07870"
     CDS             4495..4974
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390315.1"
                     /locus_tag="KH277_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07870"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_003153152.1"
                     /transl_table=11
                     /translation="MLKINEIHELIKRIDESSIDEFVYEIEGVSLKLKKNEAPAVNVTG
                     QAQAVPAAYAPAPQAAKPEAHEAAPVQEAPKQDENLHKITSPMVGTFYASSSPEAGPYV
                     NQGSKVSENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE"
     gene            4989..6341
                     /gene="accC"
                     /locus_tag="KH277_RS07875"
                     /old_locus_tag="KH277_07875"
     CDS             4989..6341
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390314.2"
                     /locus_tag="KH277_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07875"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_003153154.1"
                     /sec_met_domain="RimK (E-value: 1.5e-07, bitscore: 29.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.2e-07, bitscore:
                     29.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.9e-10,
                     bitscore: 37.0, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5e-06, bitscore:
                     24.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACKELGIETVAVYSEADKDALHVQMA
                     DEAFCIGPKTSKESYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEELNITFVG
                     PTADAISKMGTKDIARDTMQLAGVPIVPGSKGIIKNTEEAVSLAGEIGYPVIIKATAGG
                     GGKGIRVARTEEELIKGIEITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTI
                     HLGERDCSIQRRLQKLLEESPSPALDSEIREQMGEAAVKAAKAVGYTGAGTVEFIYDYR
                     EQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGQELSLRQEDVEFNGWAIECRI
                     NAENPAKNFMPSPGKINMYLPPGGLGVRVDSAAYPGYSIPPYYDSMIAKVITYGTTRDE
                     AVARMKRALSEFVIEGIETTIPFHLKLLEHETFVSGEFNTKFLETYDVMGS"
     gene            6363..6770
                     /locus_tag="KH277_RS07880"
                     /old_locus_tag="KH277_07880"
     CDS             6363..6770
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390313.2"
                     /locus_tag="KH277_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07880"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_003153156.1"
                     /transl_table=11
                     /translation="MEDNSVLKMDHDEAHLGKVEIAPEVIEVIAGIAASEVEGVAEMRG
                     NFATGVVERFGKINHGKGVKVDLADDGITIDVYCVVQFGISIPKVAASVQENIRQTLLN
                     MTSLTINEINIHIVGIQFDTKAQEVEIDEEM"
     gene            7035..7427
                     /gene="nusB"
                     /locus_tag="KH277_RS07885"
                     /old_locus_tag="KH277_07885"
     CDS             7035..7427
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153163.1"
                     /locus_tag="KH277_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07885"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_003153163.1"
                     /transl_table=11
                     /translation="MKRRTAREKALQALFQIDVSDIAPNEAIEHALDGEKTDAFFEQLV
                     YGVIEHQVQLDEMISGHLVNWKLDRIANVDRAILRLAVYEMVYTDDIPANVSLNEAIEL
                     AKRFGDDKAAKFVNGVLSNIKTDIES"
     gene            7439..8290
                     /gene="folD"
                     /locus_tag="KH277_RS07890"
                     /old_locus_tag="KH277_07890"
     CDS             7439..8290
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390311.1"
                     /locus_tag="KH277_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07890"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_007408350.1"
                     /transl_table=11
                     /translation="MTATIIDGKETAKEKREQLAKEVEELKAQGVVPGLAVILIGDDPA
                     SVSYVTGKKKAAETMGMKFKLDRFDSSLTEAELLTVIDQYNQNPEFHGILVQLPLPDHI
                     SEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNVDLSGKEVVV
                     VGRSNIVGKPVGQLLLNENATVTYCHSRTKNMSEHTKKADILVVAVGKANFIKADQIKE
                     GAIVIDVGVNRLESGKLCGDVQFDEAKEKASFITPVPGGVGPMTITMLAHNTVKSARRT
                     LS"
     gene            8414..9760
                     /gene="xseA"
                     /locus_tag="KH277_RS07895"
                     /old_locus_tag="KH277_07895"
     CDS             8414..9760
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390310.2"
                     /locus_tag="KH277_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07895"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_003153166.1"
                     /transl_table=11
                     /translation="MSEAAYVTVSALTKYIKRKFDVDPHLEDIWIKGELSNVKIHTRGH
                     IYFTLKDEHARMQAVMFQRQSSRLAFKPEDGMKVIVRGGISVYEPSGSYQLYAKEMQPD
                     GVGALYLAYEELKKKLAGEGLFDDRHKQAIPAFPATIGVVTSPTGAAVRDVITTLKRRY
                     PLVKVIVLPALVQGENASRSIVKRIEEANAQKMCDVLIVGRGGGSIEELWAFNEEIVAR
                     AIFASAIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLMERTKTAEVRLT
                     RAMQQHISKKKERVQSLQSSYAFRFPKRLYTQKEQQFDLLYQQFQSQLTGLTDRKQRQL
                     ERNTYRLTALHPETQLKQAKKRYEERSNQLARSMNVQLKQLHSQFQTVLGKLNALSPLQ
                     VMERGYSLAYKDKELIKSVDQVEQNDTLEVKMTDGVLTCEVLQKRGERK"
     gene            9757..10011
                     /locus_tag="KH277_RS07900"
                     /old_locus_tag="KH277_07900"
     CDS             9757..10011
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390309.2"
                     /locus_tag="KH277_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07900"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_007408352.1"
                     /transl_table=11
                     /translation="MTETKKSEELTFEEAMKGLEGIVAKLEEGDVPLEQAINYFQEGMA
                     LSKMCHEKLQHVEKQMDFILKDNGELAPFSVQEEDEGDK"
     gene            10001..10891
                     /locus_tag="KH277_RS07905"
                     /old_locus_tag="KH277_07905"
     CDS             10001..10891
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Geranylgeranyl pyrophosphate synthase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390308.2"
                     /locus_tag="KH277_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07905"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_014305396.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.2e-63, bitscore:
                     210.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLDAFLASRKKLIEQQLSLYTERLAMPEILKKSMLYSLEAGG
                     KRLRPLVVLAVLNAYGKDEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHK
                     VFGEAAAVLAGDGLLTESFKLITSHVSEAVSAEKRLRLVDELISAAGTEGMVGGQAADM
                     EAEQKRITLEELESIHERKTAKLLGFSVTAGAILADAPEDEVEKLRLFSSHIGIGFQIR
                     DDILDIEGHEEKIGKPVGSDTSNEKSTYPSLLTLEGAKEKLAYHISEAKRIISGLSLQK
                     ELLHDLCDLIAARDH"
     gene            11035..12936
                     /gene="dxs"
                     /locus_tag="KH277_RS07910"
                     /old_locus_tag="KH277_07910"
     CDS             11035..12936
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390307.1"
                     /locus_tag="KH277_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07910"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_024085592.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.8e-117,
                     bitscore: 387.8, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLSIQDPSFLKKMSIEQLEELSEEIRNFLITSLSASGGHIGPN
                     LGVVELTIALHKEFDSPKDKFLWDVGHQSYVHKLLTGRGKEFETLRQYKGLCGFPKRSE
                     SEHDVWETGHSSTSLSGAMGMAAARDIKGSKEYIIPIIGDGALTGGMALEALNHIGDEK
                     KDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKRIPAVGGKLAATA
                     ERIKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELFENLQYAKKTKGPVLLHVITKKG
                     KGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQELAREDDRIVAIT
                     PAMPVGSKLEGFAKEFPERMFDVGIAEQHAATMAAGMALQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFLRHIPNLVLMMPKDENEGRHMV
                     NTALSYEEGPIAMRFPRGNGLGVKMDKELKTIPIGTWEVLRPGKDAVILTFGTTIEMAL
                     EAAEELQKEGLSVRVVNARFIKPIDKQMMKAILNEGLPILTIEEAVLEGGFGSTILEYA
                     HDLGMYHTPIDRMGIPDRFIEHGSVTALLEEIGLTKAEVMNRIKLLMPPKTHKGIGS"
     gene            12933..13778
                     /locus_tag="KH277_RS07915"
                     /old_locus_tag="KH277_07915"
     CDS             12933..13778
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390306.2"
                     /locus_tag="KH277_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07915"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_015388017.1"
                     /transl_table=11
                     /translation="MTAKKERLDVLLVEKGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIARDLPLTVKGNPLKYVSRGGLKLEKALEVFPVSVKGKTMIDIGSSTGGFTDCALQNG
                     AERSYAVDVGYNQLAWKLRQDERVVVMERTNFRYSEPSDFTEGLPEFATIDVSFISLRL
                     ILPVLKTLLVPGSDCIALVKPQFEAGRESVGKKGIVRDPGVHADVLRRMNQFAASEGYT
                     VKGLSFSPITGGDGNIEFLLHLEWGGEDGNGAELPEEDILRIVREAHETLKAKKTDVPE
                     "
     gene            13875..14324
                     /gene="argR"
                     /locus_tag="KH277_RS07920"
                     /old_locus_tag="KH277_07920"
     CDS             13875..14324
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390305.1"
                     /locus_tag="KH277_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07920"
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_003153173.1"
                     /transl_table=11
                     /translation="MTKGQRHIKIRELITSHEIETQDDLVDMLREEGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRSLMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLEWEEIMGTICGDDTILIICRTPEDTEGVQSRLLELL"
     misc_feature    complement(14328..14342)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.14"
                     /tool="antismash"
     gene            14356..16086
                     /gene="recN"
                     /locus_tag="KH277_RS07925"
                     /old_locus_tag="KH277_07925"
     CDS             14356..16086
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390304.2"
                     /locus_tag="KH277_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07925"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_024085591.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIEELTISFERGLTVLTGETGAGKSIIIDAVSLL
                     VGGRGSSEFVRYGETKAELEGLFLLDSGHPVFEVCREQGIDASDDMIVMRRDINAGGKS
                     VCRVNGKLVTIAALREIGRLLLDIHGQHDNQLLMEDDKHLELLDKFAGAEAESALQAYH
                     EGYERYMELLKKVKKLSESEQEMAHRLDLIQFQLEEIESAKLELNEDELLQEERKQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLQKLSESVSSSYYLLEDA
                     TFQMRNLLDDLEYDPERLNFIETRLNEIKQLKRKYGATVEDILEYGSKIEEEIDQIENR
                     DSHLEALKKELESVGKDVAVEAANLSKIRKAWAKKLAEAIHQELQSLYMGKSTFDTEFL
                     VKTDPSASEAPVVNGQPVQLTQKGIDLVKFLISTNTGEPLKPLSKVASGGELSRVMLAM
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSTGSQVLCITHLPQVAAMADTH
                     LLIAKEFKDGRTTTHVTPLSKQDKVAEIGRMIAGVEVTDLTKRHAQELLKQAGQVKTTG
                     "
     gene            16249..17529
                     /gene="spoIVB"
                     /locus_tag="KH277_RS07930"
                     /old_locus_tag="KH277_07930"
     CDS             16249..17529
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390303.2"
                     /locus_tag="KH277_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07930"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_007408360.1"
                     /transl_table=11
                     /translation="MHDNMRKAIGVILLVSLLSVGFFKPFKEYLLIPSEMSVFENQTQA
                     VPVNASISAEKGELSEAFTLKEEHGHANITGQTQGRSEVVYDLAGFPIKKTKVRVLPEL
                     KVIPGGQSIGVKLHSVGVLVVGFHQVMTKDGKKSPGEQAGIESGDIIIKMNGHKIEKMS
                     DIAPFIQKAGKTGESLDLLVKRDKQKIKTKLIPTKDEAEGKYRIGLYIRDSAAGIGTMT
                     FFEPKTKKYGALGHVISDMDTKKPIVVEDGEIVRSTVTSIEKGKGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIKNNISDKALPIALSNEVKKGPAQMLTVIENDKVEKFD
                     IEIVSTTPQKFPATKGMVLKVTDPKLLKRTGGIVQGMSGSPIIQNGKVVGAVTHVFVND
                     PTSGYGVHIEWMLSEAGVDVYGKDKAS"
     gene            17810..18610
                     /gene="spo0A"
                     /locus_tag="KH277_RS07935"
                     /old_locus_tag="KH277_07935"
     CDS             17810..18610
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390302.1"
                     /locus_tag="KH277_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07935"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_003153177.1"
                     /transl_table=11
                     /translation="MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLF
                     KDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSIIHEI
                     GVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVA
                     WSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     gene            complement(18756..19937)
                     /gene="alr"
                     /locus_tag="KH277_RS07940"
                     /old_locus_tag="KH277_07940"
     CDS             complement(18756..19937)
                     /EC_number="5.1.1.1"
                     /GO_function="GO:0008784 - alanine racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="alr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389646.1"
                     /locus_tag="KH277_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07940"
                     /product="alanine racemase"
                     /protein_id="WP_015388018.1"
                     /transl_table=11
                     /translation="MKKLCREVWIEVDLDAIKKNVRAIRRHIPNTSKIMAVVKANAYGH
                     GSVEVARQALESGASELAVASVEEGIVLRRAGIKAPILVLGFTALSCVKKSAVWNITLS
                     AFQVSWIKKANRILEKEAESKRLSIHINVDTGMGRLGVRTEEDLLAVVKALKSSTYLSW
                     DGIFTHFSTADEPDTELTMLQHEKFISFLRFLKNQDITLPTVHMCNTAAAIAFPEFSAD
                     MIRLGIGLYGLYPSASIKELNLVDLTPALSLKARIAYVKAMVTDPRTVSYGATYIAEPG
                     EIIATIPIGYADGYSRALSNRGFILHRGRRVPVAGRVTMDMIMVSLGENEGKQGEEVVI
                     YGKQQGAEISVDEIAEMLGTISYEVLSVLSRRIPRFYFRDGKIIKISAPVLYV"
     gene            complement(20112..20324)
                     /locus_tag="KH277_RS07945"
                     /old_locus_tag="KH277_07945"
     CDS             complement(20112..20324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153181.1"
                     /locus_tag="KH277_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07945"
                     /product="spore germination protein"
                     /protein_id="WP_014305392.1"
                     /transl_table=11
                     /translation="MSGCPITINNVSGNGVVNVGGAISISPLTASKTVFGAGGGNIGIV
                     IQNNAVSQSKMFEHQFSDQNIVKSL"
     gene            complement(20450..20662)
                     /locus_tag="KH277_RS07950"
                     /old_locus_tag="KH277_07950"
     CDS             complement(20450..20662)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153181.1"
                     /locus_tag="KH277_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KH277_07950"
                     /product="spore germination protein"
                     /protein_id="WP_003153183.1"
                     /transl_table=11
                     /translation="MAGFPITINSLSGNGVVNVGGAFSISPLTVSKTVYGSGGGNTGMV
                     LQMNQSSTSQSSNSQYSDQNVTKTL"
     misc_feature    20858..20872
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.83"
                     /tool="antismash"
ORIGIN
        1 ttcattctga cggcgacgac atggacggga tttgagatcg ccaaaatgta tattgaaagg
       61 ccgagacaga tccgtcagct gcgcgcggcg ctccaatcgc ttgaagcgga aatcatgttc
      121 gggcatacgc cgctgcacat agcttcggga caaatcgccg cacagctttc caagcctgta
      181 tcgtcattgt ttcaagcttt cagcaggagg cttgagcagg gaagcgattc cgccaaaacg
      241 gcctgggaac agagcttgaa acataactgg ccctccatgg cgatgaaaaa aagcgaatac
      301 gatgtgctga agcaattcgg agagacgctc gggctccatg accgtgtttc tcagcagaaa
      361 catatcaagc ttgcgcttac acatttggaa gcggcggaag cggatgccgg acgggcgcag
      421 gcgaaaaatg aaaaaatggt gaaaagctta ggatttttag ccggactgtt actcattctt
      481 ctattgatgt aaacatgagg ggagcaaaca taaaatggga gtcgacgtaa atgtcatttt
      541 tcaaatcgcc ggagtcggta tcgtggttgc gtttctgcac accatacttg accaaatggg
      601 aaaaaaagaa tacgcccaat gggtgacgct gcttggcttt atctatattt tatttatggt
      661 ggcgacgatt gtcgatgacc tgttcaaaaa gatcaaagct gtgtttctat tccaaggata
      721 ggggggctta cagattgaga ttgttcaaat tgtaggttta ggcctgatcg ccacatttct
      781 ctccctgatc gtaaaagaac agaaaccgac tttcgcgttt atgattgtcg tcttcagcgg
      841 ctgcgtgatc tttctctatc tcatcgatca gatttacgac attatcagaa tgatagaaaa
      901 aatagccgtc aatgcaaatg tcaatatggt ctatgtggaa accattttaa aaattatcgg
      961 catcgcctac atcgctgaat tcggtgcgca gctgacaaag gatgcgggcc agggagcgat
     1021 tgcttcgaaa atagagctgg ccggaaaaat tttgatactg gtaatggccg tgccgatact
     1081 caccgtcatt attgaaacga ttctcggact tattccttct tgatcatcaa taaaatggaa
     1141 agggggggca caaaaaatga agcgctttcg gtgggcgggg gcttttttgt tcatcctctt
     1201 attttttcag actgaatgtg tacaagctgc cggaacagac ggtgcgtcgc aggaaaccgc
     1261 agttcaccaa gaatccgctg atgaagtggc gaaaaagcag gccgaagcgc tgaaaacaga
     1321 aggcatcgga aagttttggg acgacatcat gacagaatac ggcggtcttc tgcctgaaag
     1381 ccaaaaggga agcatcatcg actttattaa cggtgaaaaa acgttctcgc cggaggcatg
     1441 gctgaaggct ttattttcat acttgtttca tgaagtgctc gcaaacggaa agcttctggg
     1501 aactttgatt cttctcacca tcttttgtgt cattctgcag cttttgcaaa atgcgtttca
     1561 gcagagcact gtcagcaaag tggcttatgc aatcgtctac atggtgctga ttattctcgc
     1621 tttaaacagc tttcatgttg ccgtcaatta tgccagtgaa gcgatccaga cgatgacaag
     1681 tttcattctc gcgctcatcc cgcttttact cgcgcttttg gcgtcttccg ggggagccgt
     1741 ctccgcagct ttttttcacc ccgttatttt atttctgatg aatacgagcg gccttctcat
     1801 tcaaaacatt gtcatgccgc ttattttcct gtcagcgatt ttaagcatcg tcagcacgat
     1861 gacggatcaa tataaagtca cgcagcttgc caatctgctc agaaatatcg cgatcggcgc
     1921 gcttgccgta tttctcaccg tgtttctcgg cgtcatctcc gtacaggggg cttcggctgc
     1981 cgtgacggac gggattacgc tcaggactgc aaaatttatc acaggcaatt ttattcccgt
     2041 gctcggccgg atgtttacgg atgcgacgga tacggtcatc agcgcatcgc tcctattaaa
     2101 aaacaccgtg ggaatcctag gagtcggaat tttgatctgc atctccgcgt ttccggcgat
     2161 caaagtgctc tcgctcgctt ttatttataa gctcgcggcc gctattctgc agccgctcgg
     2221 aggcgggccc gtcattacgt gcctcggcgt catcagccga agcgtgctgt atattttcgc
     2281 ggcgctcgcc atcgtctctc tcatgttttt cctcagtatt acagtcatta ttacagcagg
     2341 caacctcacc atgatgatga aataaaggag gcccattgga tatgagcttt ttaacagaat
     2401 ggctgacaag cattattttg tttatcttat tcgccatcgt catcgacatg ctgctgccca
     2461 gctccagtat gcaaaaatac gccaagatgg ttgtcagcct gctgttaatc attgtcatgc
     2521 tcaacccgat cttcaaactt ttcaaaacag acccggaaat catcttcgat tatttgacaa
     2581 aacaagagca atctcaatcc gctgatataa aaaatcaaat caaatcagaa aaaaaagaaa
     2641 tacaagcatc aaaccgcgca tatgttttag aagaaatggc tgtccaacta aaaaagaaag
     2701 cggaggagat gttcagtcat gacgaataca aaatagacga catccgcctt acagcggaag
     2761 aacaggttcg ttcagaagaa gatgtaaaaa cgatcagcgt gtatatggcc ccatcttctg
     2821 aaaaaaccgt gcaaaccgtc gcaccgatcg acatccgcac agaccgcaaa tacgaaccgg
     2881 aaggcgcagc cgacaaaaaa gaggccgcag acatcaaaga aaaacttgcg gatatatggg
     2941 aaatcggcag tgagaaaatt acggtttata tggaaggcgg ggagaaaaac ggccatgaat
     3001 aaaaacggac tatggaccat actcaaaaaa cagctgatga tcggacaggc gaaagacgga
     3061 gaaaaaccaa aactgacaaa atatcattac tttctgttcg tgtttgtgct cggagtatct
     3121 tttatgctgg tgagccagct gttctcttca ccggagaaaa ccgggaagga ccaagcggcg
     3181 cagaccgtca tgtccggccg aacggaagac aaaagcgggc aaaaaagcgc acccgttttt
     3241 aaggcatcga aagacagcag cgccaaaaac acgatcgatg attatgaaag agactatgaa
     3301 aaccagctga aagaaatcct tgaaacgatt atcggcgtgg aggatgtatc aattgtcgtg
     3361 aacgtagacg caacatcttt gaaagtgttt gagaaaaata aaacgaaaaa agacaccacc
     3421 accgaagaaa ccgataaaga aggcggcaaa agaagcgtaa ccgatcaaac ctctgaagaa
     3481 caaattgtca tgattcgaaa cggggatcag gaaaccccgg tcgtcgtcca gacgaaaaag
     3541 cccgatatcc gcggtgtact cgttgtcgct cagggagtgg acaacgttca aataaaaaaa
     3601 accatcattg atgccgtcac aagggtgctt gatgttccga gctaccgtgt agcggttgcc
     3661 cctaaaaaaa tcaaggagga ttcataaatc atgctgaaaa aacaaacggt ttggctttta
     3721 acaatgctca gtctcgtcgt ggtattaagt gtttattata ttatgtcgcc ggaaagcaaa
     3781 aatgccgtgc agatgaaaag cgaaaaaagc agcggagaag tggcaactga aaaaacgccg
     3841 gctcctgaaa cgaaagataa gaacggaagc ggcacggata aagaagacgg aacaaaagga
     3901 acgaaagatt ctaaaggcgc aaaagaggat aaagaaacat cagccgaagc atcggacaaa
     3961 gacggaacgg tcgctacaga aacagctgat gaaaacttat ttaccgcata ccgcatggaa
     4021 cttgaagacg caagaagcaa agaaagggaa cagttaaaca gcattgtttc aagcgatgat
     4081 gcgaccgcaa aggaaaaaag cgaagcctac gataaaatga cggcgctgag caatgctgaa
     4141 gggacggaaa aacagctgga aacgctgatt aaaacacaag gctacaaaga tgcgctcgtg
     4201 gatgctgaag gagacaaaat caacattacg gtcatgtctg acaaacattc aaacgcaaaa
     4261 gcttccgcta tcattgacct ggtggaaaaa gaaatcaaga cgatgaaaga cgtcgccgtc
     4321 acgtttgaac cgacaaaata agagatctcc accgcccgca cccgctgcgg gcttttctga
     4381 tgtcatttta gatcagtgtt gaatttacac aagcgctcct gtaagataaa catagtatgt
     4441 acttttagta gcaacccata aatttctatt ttttatacat aggagtggaa actgatgtta
     4501 aaaatcaacg aaattcatga actgataaaa agaatcgatg aatcttccat cgacgaattc
     4561 gtttacgaaa tcgaaggcgt aagcctcaaa ctgaaaaaaa atgaagcgcc ggcagtgaat
     4621 gtaacgggac aagctcaagc cgttcccgcc gcttacgcac ctgctccgca ggctgcaaaa
     4681 ccggaagcgc atgaagccgc tcctgttcag gaagcgccga aacaagacga aaacctgcac
     4741 aaaattacgt ctccgatggt cggaacgttt tatgcttctt catcgccgga agccggccct
     4801 tacgtaaacc aaggttcaaa agtgagcgaa aatacagttg tttgtatcgt agaagcaatg
     4861 aaactcttta acgagattga agccgaagta aaaggagaaa tcgttgaagt gttagttgaa
     4921 aacggccagc tggtcgaata cggacaacct ctatttcttg taaaagctga gtaaggagac
     4981 ctgctattat gattaaaaag ctattgatcg ccaaccgagg agaaatcgcc gtcagaatca
     5041 tccgggcctg caaagagctg ggcattgaaa ctgtagccgt ttattctgag gcagataaag
     5101 acgccctgca tgtccaaatg gccgatgagg ctttttgtat cgggccgaaa acatcaaaag
     5161 aaagctattt aaatgtaacg aacatcgtca gcgtcgcaaa gctgaccggc acggatgcga
     5221 ttcatccggg atacgggttt ttagctgaaa acgccgactt tgccgagctg tgcgaggaat
     5281 tgaacataac gtttgtcggc cctacggctg acgccatttc aaaaatggga acaaaagata
     5341 tcgcgcgcga cacgatgcag ctggcgggcg tgccgattgt gcccggttca aaaggaatca
     5401 taaaaaatac cgaagaagcg gtttcgcttg caggtgaaat tgggtatcct gtgattataa
     5461 aagccactgc gggcggaggc ggaaaaggca tccgggtcgc acgcacagaa gaagaactga
     5521 tcaaaggcat tgagattacc cagcaggaag ccgctacggc attcggaaat ccgggtgtgt
     5581 acatcgagaa gtacatagaa gatttccgcc atgttgaaat tcaggtgctt gcggataatt
     5641 acggaaacac gatccatctc ggagagcgtg actgttctat ccaaagacgt ctgcaaaaac
     5701 ttcttgaaga gtcaccgtca cctgcgcttg attctgaaat cagggagcag atgggcgaag
     5761 ctgcggtaaa agcagcgaag gccgtcggtt acacgggagc cggcacagta gaattcattt
     5821 atgactacag agaacagcgc tactacttca tggaaatgaa cacgcgtatt caagtagagc
     5881 accctgtcac agaaatggtg acgggaacgg atctgatcaa agaacagatc aaagtggcat
     5941 ccggacagga gctttcgctc agacaggaag acgttgaatt taacggctgg gcgattgaat
     6001 gccgcatcaa tgctgaaaat cctgcgaaaa acttcatgcc ttcacccggt aaaattaaca
     6061 tgtacctgcc gccgggcgga ctcggcgtac gcgtggattc agccgcatat cccggctatt
     6121 cgatcccgcc gtactatgac agtatgattg ctaaagtcat cacatacgga acaacgcgtg
     6181 atgaggcagt cgcacggatg aaacgcgcgc tgagcgaatt cgtgattgaa ggtattgaaa
     6241 cgacgattcc gttccatctg aaactgcttg aacacgaaac atttgtcagc ggagagttta
     6301 atacaaagtt tttagaaaca tatgatgtaa tgggctcata atttttgcgg gaggtgaatt
     6361 gaatggaaga caacagtgtg cttaaaatgg atcatgacga ggctcattta ggcaaggttg
     6421 aaattgctcc tgaggtcatt gaagtcattg ccggcatcgc cgcttccgaa gttgaaggag
     6481 ttgctgaaat gcgcggcaat ttcgccaccg gcgtcgtaga acgcttcggc aaaatcaatc
     6541 acggtaaagg cgtaaaggtc gatttagccg atgacgggat taccatcgac gtctattgcg
     6601 tcgttcaatt cgggatctcg atcccgaaag tggcggcaag cgttcaggag aatatccgcc
     6661 aaaccttatt aaacatgacg tctctgacca ttaatgaaat caatattcat atcgtcggca
     6721 ttcaatttga cacgaaagcc caagaagtcg aaatcgacga agaaatgtaa tgagcgtata
     6781 aaaaccaagg ggatgggcag ccctttggtt ttttatacgt ttcccgtcat ttcaggcatg
     6841 aagaaagccg gcttacaaac ggcagccgag tttcttcatg ctgtgaaatc cgaatgaaat
     6901 taatacggtt tgtgaaaata ttcggcatta gggtgaaaaa acctaaattt cgacatgcga
     6961 ttgagaaaaa aatatgttat gatctcttta agcttaacga caagcggata aagcggatct
     7021 gaaggagaaa gaaaatgaaa agaagaacag ctagagaaaa agctttgcag gcactttttc
     7081 agattgatgt cagcgatatt gcaccgaacg aggccattga gcacgcgctt gatggtgaaa
     7141 aaacagatgc cttctttgaa cagctggtgt acggagtgat cgaacatcag gttcagcttg
     7201 atgaaatgat ttccggccat ctcgtcaatt ggaagcttga ccggattgca aacgtagacc
     7261 gcgcgatcct gcgtctggcg gtgtatgaaa tggtttatac tgacgacatt cctgctaacg
     7321 tgtcattaaa cgaagcaatc gagctggcaa aacggttcgg cgacgataaa gctgcaaaat
     7381 tcgtaaacgg ggttctttct aacattaaaa ctgatatcga atcataggag gaaagaaaat
     7441 gactgcaaca atcatcgacg gaaaagaaac ggctaaagaa aaacgcgaac aattggcgaa
     7501 agaagtagaa gagctgaaag cacaaggcgt agtgcccggt ttggcggtca ttttaatcgg
     7561 agacgatccc gcttctgttt catatgtgac aggcaagaaa aaagccgctg aaacaatggg
     7621 aatgaaattt aagcttgacc gctttgactc aagcttaacc gaggcggagc ttttaacagt
     7681 gattgatcag tataatcaaa atccggaatt ccacggcatt ctcgtccagc tgccgcttcc
     7741 ggatcatatt tctgaaaaag ccgtaatcga gcggatctct cccgataagg atgttgacgg
     7801 tttccaccct ctcaacgtcg ggaaaatgct gcttggcgaa gatacatttc ttccatgcac
     7861 gccgcacgga attgtcgagt tattgaaaaa gacgaacgta gatctttccg gcaaagaagt
     7921 tgttgtagtc ggacgaagca atattgtcgg taaaccggtc ggccagctgc tgctgaacga
     7981 aaacgcgacc gtcacatatt gccattcccg cacgaaaaat atgtctgagc atacgaaaaa
     8041 agcagatatt cttgtggtag cggtcggtaa agcgaatttc atcaaagccg atcaaatcaa
     8101 agagggcgcc attgtcattg atgtcggcgt caaccgtctc gaaagcggaa aactctgcgg
     8161 agacgttcag tttgatgaag cgaaagaaaa agcatctttc attacgccgg tgccgggcgg
     8221 agtaggtccg atgaccatca caatgcttgc gcataatact gttaaatctg ccagacgtac
     8281 gttatcatag ataaccggag acagtcacaa aaagtgtgac aatgagcacg atacccgctt
     8341 cttaaggctc ctttcagcca gagcgggttt tcttagttta gggcaaaaag cctttatgaa
     8401 aggagtgcag gatgtgagtg aagcggcata tgtcacggtt tccgcgctga ccaaatacat
     8461 taaacgaaaa ttcgatgtgg accctcatct tgaagacatt tggattaagg gtgagctctc
     8521 caatgttaaa attcatacga gaggccacat ctattttaca ttaaaagatg agcacgcccg
     8581 catgcaggcc gtcatgtttc aaagacaaag ttcgaggctt gcgtttaagc ccgaggacgg
     8641 aatgaaggtc atcgtaagag gcggcatttc cgtctatgaa ccgagcggaa gctatcagct
     8701 gtacgcgaaa gaaatgcagc cggacggtgt gggggcgctc tacttagcat atgaagaatt
     8761 aaagaaaaaa cttgccggcg aagggttgtt tgatgaccgg cataagcagg ccatccccgc
     8821 atttccggct acgatcgggg tcgtcacgtc accgacggga gcagccgtca gagacgtcat
     8881 taccacactc aaaagaagat acccccttgt gaaagtcatt gtgcttcccg cactcgttca
     8941 aggtgaaaat gccagcagat cgattgtgaa gcgcattgaa gaagccaatg cacaaaaaat
     9001 gtgtgacgtc ctgatcgtcg gaaggggagg gggctcgatc gaagaattgt gggcatttaa
     9061 cgaagaaatc gtagcccggg cgatttttgc ttccgccatt ccgattatat cagccgtcgg
     9121 acatgaaaca gattttacaa tcagtgattt cgtcgcggat atccgggcgg caacgccgac
     9181 aggagcggca gaaatcgccg tcccgcacac gacggactta atggaacgga caaaaacggc
     9241 ggaagtccgg ctgacaagag cgatgcagca gcatatcagc aagaaaaaag aacgggttca
     9301 atcgctccag tcatcctacg cgttccgttt tccgaaacga ttgtataccc aaaaggaaca
     9361 gcagtttgat cttttgtatc agcagttcca atcacagctc acagggctta cggacaggaa
     9421 acaaaggcag ctggagcgga atacgtacag attaacggcg cttcaccctg aaacccagct
     9481 gaaacaggcg aaaaaacggt acgaggagcg ctcaaatcag ctcgcccgaa gcatgaatgt
     9541 ccagctgaag cagcttcatt cgcagtttca gacggttctt ggtaaactga atgcattaag
     9601 tccccttcag gtgatggaga gaggatacag tctggcctat aaagataaag agctgatcaa
     9661 aagcgttgat caagtcgaac aaaatgatac gcttgaagta aagatgacag acggcgttct
     9721 gacgtgtgaa gtattgcaaa agagaggcga acgaaaatga cagaaaccaa aaaaagtgaa
     9781 gagctgacat ttgaagaggc gatgaaaggc cttgaaggca ttgtggcaaa gcttgaagaa
     9841 ggagacgtgc cgcttgagca ggcgattaat tattttcagg aagggatggc cctttcaaaa
     9901 atgtgccatg aaaagcttca gcatgtcgaa aagcaaatgg actttatttt aaaagataac
     9961 ggcgaacttg cacctttcag cgttcaggag gaagacgaag gtgacaaata aactggacgc
    10021 atttttagca tcgcgcaaaa aactgattga acagcagctt tctttgtata cggaacggct
    10081 tgcgatgcct gaaatcctca aaaaatctat gctgtattct ttggaagcgg gcggaaagag
    10141 gctgcgcccc ctcgtcgtct tagccgttct gaatgcttac ggaaaagatg aaaaagacgg
    10201 gattccggtc ggatgcgctg tcgaaatgat tcatacgtat tccttaatcc atgatgatct
    10261 tccttgcatg gacgatgatg atctgcgccg gggaaagccc acaaaccata aagtcttcgg
    10321 agaagcggca gccgtattgg ccggagacgg gcttctgaca gaaagcttta aattgatcac
    10381 atcccacgtg tctgaggcgg tttcagcaga aaaacggctc cgtctcgtcg atgagctgat
    10441 cagcgcggca ggaacggaag gaatggtcgg cgggcaggct gccgacatgg aagcggaaca
    10501 aaagcggata acgcttgagg agctggaatc catccacgag cggaaaacgg ccaagctcct
    10561 cggtttttct gtgacggcgg gcgccatttt ggcagatgcg ccggaggatg aagtcgaaaa
    10621 gctgcgtctg ttcagcagcc atatcggcat cggatttcaa atcagagatg acatccttga
    10681 tattgaaggg catgaggaga agatcggcaa accggtcggc tcagacacgt cgaatgaaaa
    10741 gtcaacgtat ccgtcgcttt taacgcttga aggcgcgaaa gagaagctgg cgtatcatat
    10801 cagcgaggcg aaacggatca tcagcggcct ttctcttcag aaagaactgc tgcatgacct
    10861 ctgtgattta atcgcggcga gagatcatta aaaacggtcc tgatttgaag gggctgccgc
    10921 tcctatggta aaatgtaagc agtttcgatg aaaatacaaa gggagtcttt ttcttttttc
    10981 aaaaagacac tgtttaattt gcagaaattc atgctgaaag tgagttgatc cgctttggat
    11041 cttttatcaa tacaggaccc gtcatttctt aaaaagatgt caattgaaca gctggaagag
    11101 ctgagtgagg aaatccgcaa tttcctcatc acatcactgt ctgcctctgg cggccatatc
    11161 gggccgaacc tcggggttgt cgagctgaca attgcgcttc acaaagaatt tgacagtccg
    11221 aaagataaat ttttatggga tgtcggacat cagtcctatg ttcataaact gttaaccggg
    11281 cgcggcaagg agtttgaaac cttgcgccaa tataaagggc tttgcggttt cccgaagcgc
    11341 agcgaaagcg aacatgacgt atgggaaaca ggccacagct caacatcgct ctcaggcgcg
    11401 atgggaatgg cagccgcccg tgatattaaa ggatcgaaag aatatatcat cccgattatc
    11461 ggagacggcg ctttaaccgg aggaatggcg ctcgaagcgc tgaaccatat cggtgatgag
    11521 aaaaaagata tgatcgtcat cctgaatgat aatgagatga gcattgcgcc gaatgtcggg
    11581 gcgattcatt ctatgctggg acggcttcgc acggccggca aatatcaatg ggtaaaagac
    11641 gagcttgaat atttatttaa gcgcatcccg gccgtcggcg gaaaattggc cgccacagcg
    11701 gaacggataa aagacagctt aaaatatatg cttgtgtcag gcatgttttt tgaagagctg
    11761 ggctttacgt atttaggccc tgttgacggt cattcttacc acgaactgtt tgaaaacctg
    11821 caatacgcca aaaaaacgaa aggtcctgtc cttttgcatg tcattacgaa aaagggcaaa
    11881 ggctataaac cggctgagac cgacacaatc ggcacatggc acggaacggg gccttataaa
    11941 atcaatacgg gtgatttcgt caagccgaaa gccgcggcgc cttcatggag cggacttgtc
    12001 agcggcaccg tgcaggagct ggcgcgcgag gatgacagaa ttgtcgcgat tacaccggct
    12061 atgccggtcg gctctaagct tgaaggattt gcgaaagaat ttcctgagcg catgtttgac
    12121 gtcggaatcg cagaacagca tgcggcgaca atggccgcgg gaatggcgct tcagggtatg
    12181 aagccgtttc ttgcgattta ttcgaccttt ttacagcggg cgtacgatca ggtcgtccat
    12241 gatatctgcc gtcaaaacgc gaatgtattt atcggcattg accgcgccgg tttggtcggc
    12301 gctgacgggg agacgcatca aggcgtcttt gacatcgcct ttttgcggca tataccgaac
    12361 ctcgttttaa tgatgccgaa ggatgaaaat gaaggccgcc atatggtcaa tacagccctt
    12421 tcatacgagg aaggtccgat tgcgatgcgc ttcccgcgcg gaaacgggct cggcgttaag
    12481 atggataaag agctgaaaac cattccgatc ggaacatggg aagtgctccg tcccggaaaa
    12541 gacgcggtca ttttaacatt cggtacgacc attgaaatgg cgctggaagc ggctgaagaa
    12601 ctgcaaaaag aaggcctgtc cgtgcgtgtc gtgaatgcga ggttcataaa gccgattgat
    12661 aaacaaatga tgaaggccat tcttaatgaa ggtctgccga ttttaacgat agaagaagct
    12721 gtgcttgaag gcggattcgg cagcacgatt cttgaatacg ctcatgacct cggcatgtat
    12781 catacaccga ttgacagaat gggcatccca gaccggttta ttgaacacgg cagcgtaacc
    12841 gccctgcttg aagaaatcgg tctcacgaag gctgaggtta tgaatcggat aaaactgctg
    12901 atgccgccga agacacataa aggaattgga tcatgacagc aaaaaaagaa cgattagatg
    12961 tacttcttgt agaaaaaggc cttgcggaaa cgcgggaaaa agcgaaacgc gccattatgg
    13021 cgggcatcgt atactcaaat gaaaaccgat tggacaaacc gggtgaaaaa atcgcccggg
    13081 atcttccgtt aacggtaaaa ggaaaccctc ttaaatacgt cagcagaggc ggattaaaac
    13141 ttgaaaaagc cttggaagtg tttcctgtct cggtaaaagg caaaacgatg attgacatcg
    13201 gctcgtctac agggggattc acggattgcg ccctccaaaa cggagctgag cggtcctacg
    13261 cagtggatgt cggctataat cagcttgctt ggaagctcag acaggacgag agggtcgtcg
    13321 tcatggaacg gacgaatttc cgctattccg agccttccga tttcacagag ggtttgccgg
    13381 aatttgcgac aatcgatgtt tctttcatct cactccgcct cattctgccg gttttaaaaa
    13441 cgctgcttgt accggggagc gattgtatcg cactggtgaa gccgcaattt gaagccggac
    13501 gggaatccgt cggaaaaaaa ggcattgtca gagatcccgg cgttcatgct gacgttctcc
    13561 gccgcatgaa tcaatttgcc gcttctgaag gatatacagt gaaaggactg tccttctcac
    13621 cgattacagg gggagacggc aatattgagt ttctgcttca tctggaatgg ggcggagaag
    13681 acggaaacgg cgctgaactg ccggaagaag atattctccg tatcgtccgc gaagcacatg
    13741 agacattaaa agccaaaaag acagatgtac cggaataata gggggctatt attccttttt
    13801 tctgccatca tgtacttttt atcaagaagc ggttaacata atgacaagaa cagcttgaaa
    13861 acagaggtgc ttacatgaca aaaggccaaa ggcatataaa aatcagagag cttattacaa
    13921 gccatgagat tgaaacgcag gatgacttag ttgacatgct gagagaagaa ggatataagg
    13981 taacccaggc gactgtctcc agagacatta aagagctgca tctcgtaaag gtgccgacga
    14041 acaacggctc ctacaaatac agcctgccgg cggatcagcg gttcaatccg ctgtcaaaac
    14101 tgaagcgttc attaatggat gcgttcgtaa aaattgactc agcaagccat atgatcgtat
    14161 taaaaacgat gccggggaat gctcaggcaa tcggcgctct gatggataat ctcgaatggg
    14221 aagaaatcat gggcacgatc tgcggagatg acacgatctt aatcatctgc aggacgcctg
    14281 aagatacgga aggcgtacaa agccgtcttt tggagctgct gtagcgtaat tatcagataa
    14341 aaggtggaat gctgtttgtt agctgaacta tcaataaaaa actttgccat tatagaggaa
    14401 ctgacgattt cgtttgaacg ggggctcacc gtcctgacgg gagaaacagg ggccggcaag
    14461 tcaattatta tagacgccgt ttccctatta gtcggcggac gcggctcgtc cgaatttgtc
    14521 cgttacggtg aaacaaaggc cgagcttgaa ggactgtttc tattggacag cggtcatccc
    14581 gtttttgaag tatgccgtga gcagggaata gacgcatctg acgacatgat tgtcatgaga
    14641 agggacatca atgccggagg aaaaagcgtc tgccgtgtca acggaaaatt agtgacgatt
    14701 gcggctttaa gggaaatcgg cagactttta ttagatattc acggacagca tgataaccag
    14761 ctgttaatgg aggacgacaa acacttggag cttttggata aatttgcggg cgctgaggcc
    14821 gaatccgcgc ttcaggctta ccatgaaggc tatgagcgtt atatggagct gctcaaaaaa
    14881 gtgaagaagc tgtcagaaag cgagcaggaa atggcgcatc ggttagacct gattcaattt
    14941 cagcttgaag aaatcgagtc ggcgaagctt gaattgaatg aagacgaact tcttcaggaa
    15001 gagcggaagc agatatccaa ctttgaaaaa atttatgaat cattgcaaaa cgcctataat
    15061 gcgctccgca gcgagcaggg ggggcttgac tgggtcggaa tggcctctgc ccagcttgaa
    15121 gatatttcgg atatcaatga accgctgcaa aagctgtctg aaagtgtgtc aagttcctat
    15181 tatctgctgg aggatgcaac ctttcaaatg cgcaatctgt tagatgatct ggaatatgac
    15241 ccggaacggc tgaattttat tgaaacccgt ttaaatgaga tcaaacagct gaagcgcaaa
    15301 tacggagcga cggtagaaga cattttggaa tacggctcta aaatagaaga ggaaatcgat
    15361 caaatcgaga accgcgacag ccaccttgaa gccctgaaga aggaattgga gtcggtcggc
    15421 aaagatgtgg ccgtagaagc cgccaattta tcaaaaatca gaaaagcatg ggccaagaaa
    15481 ctggcggaag cgattcatca ggaattacaa agtctgtata tgggcaaatc aacgtttgat
    15541 acggaatttc tcgtgaaaac cgatccgtca gccagtgaag caccggttgt taacgggcag
    15601 cccgtgcagc ttacccaaaa ggggatcgac cttgtgaagt ttttaatttc aacaaacacc
    15661 ggtgagcctt taaaaccgct gtcaaaggtc gcttccggag gcgagctttc aagggtgatg
    15721 ctggcgatga agagtatttt ttcttcccag caggatgtca cctccatcat ctttgacgaa
    15781 gtggacaccg gtgtaagcgg gcgggttgcc caagccatcg cggaaaaaat ccataaagta
    15841 tcgaccggtt cacaggtgct ctgcattaca cacctgccgc aggttgccgc tatggcggat
    15901 acgcaccttc tgatcgcaaa agaattcaaa gacggacgga cgacaacgca tgtcacgccg
    15961 ctttccaagc aggataaggt agcggaaatc ggccgcatga ttgcgggtgt tgaagtgacc
    16021 gatctgacaa aacggcatgc acaagagctt ttaaaacagg ccggacaggt aaaaacgaca
    16081 ggataagctg ctgatacagg cagcttattt tttgttccat ttctctaaca gtgtatccaa
    16141 tgtttttctt cgtatgccgg ttataaatca agcgcaggaa ggcaaaagta tagatgtagc
    16201 agaaaaagaa agtggtgtgg gataggagcg aggagagtga aggaatgaat gcacgataac
    16261 atgaggaaag caataggtgt aattctcctt gtttctttac taagtgtagg cttttttaag
    16321 ccgtttaaag aatatttact gataccgtca gaaatgagcg tctttgaaaa ccagacacag
    16381 gccgttccgg tcaatgcatc aataagcgct gaaaagggcg aattatcaga agcctttacg
    16441 ctgaaagaag agcacggtca tgcaaacata acagggcaaa cacaaggcag gtcagaagta
    16501 gtatatgatc ttgccggatt tcccattaaa aaaacgaaag tgcgtgtcct tcctgaattg
    16561 aaggtcattc cgggcggaca gtccatcggt gtaaaactgc attcagtcgg tgttttggtc
    16621 gtcggttttc accaggtgat gacaaaggat gggaaaaagt ctccgggaga acaagcgggt
    16681 attgaatctg gcgacatcat tattaaaatg aacggacata aaattgaaaa aatgagcgac
    16741 atcgccccgt ttattcaaaa agcgggcaaa accggtgaat ctctggattt attggtgaaa
    16801 cgcgataagc aaaaaatcaa aacaaagctg attccgacaa aggacgaagc cgaggggaaa
    16861 tatcgaatcg gcctttatat ccgtgattcg gcagccggca tcggcaccat gacatttttt
    16921 gaaccgaaaa caaaaaaata cggcgcattg ggccacgtca tctctgatat ggatacaaaa
    16981 aaaccgattg ttgtagaaga cggagaaatc gtccgttcta ctgtaacatc gattgaaaaa
    17041 ggaaaaggcg gcaatccagg cgaaaaactg gcaaggtttt cgtcagaacg gaaaacgatc
    17101 ggcgatatta accgcaacag cccgttcggc atttttggga cactgcatca gccgattaaa
    17161 aacaacattt ccgacaaagc gcttccgatt gctttgtcaa atgaagtaaa aaaaggacct
    17221 gcgcaaatgc tgacggttat cgaaaacgat aaagtagaga aatttgatat tgaaatcgtc
    17281 agcaccacgc cgcaaaaatt cccggcgaca aagggaatgg tattgaaagt gacagatccg
    17341 aaactgctga aaagaaccgg cggaatcgtt caggggatga gcggaagccc gatcatccag
    17401 aacggaaagg tcgtcggagc cgtaacccac gtatttgtca atgatccgac aagcggctat
    17461 ggcgttcata tcgaatggat gctgtctgaa gcgggtgttg atgtttacgg gaaagacaaa
    17521 gcaagctgac tgccggatga tccggcagtt tttttatgtg atgcgttctt cacttctttc
    17581 cgggattcat gtaaaataag acatgaagat ttttcgacaa attcacgttt cctgatttgt
    17641 caaacttaat ttttagtcga aaaacctaga aaatgctaga aaaacaaaga tataccacta
    17701 ttattggtaa atatggattt tttaaaaggg gaagtagtgg ttttgtcgaa tgtaacatat
    17761 agcagtcaaa tgggttgcgt cctgttaata cattggggga ggaagaaacg tggagaaaat
    17821 taaagtttgt gttgctgatg ataatcgaga gcttgtaagc ctgttgagtg aatatataga
    17881 gggacaggat gatatggaag tgatcggcgt tgcttataac ggacaggaat gtctttcttt
    17941 gtttaaagat aagaatcccg atgtgctcgt gttagacatt atcatgccgc atctggacgg
    18001 acttgcggtt ttggagcgtc tgcgtgaatc agagcttgag aagcagccga acgtcatcat
    18061 gctgacggca ttcggtcagg aagacgttac gaaaaaagcc gtcgatttag gcgcatccta
    18121 tttcatcctg aagccgtttg atatggaaaa ccttgtcggc catatccgcc aggtaagcgg
    18181 aaatgtcagc agtgtcacac accgtgcgcc gtctgcgcaa agcagcatta tccgcagcca
    18241 gccggagccg aagcggaaaa atctcgatgc cagcattaca agcattatcc atgagatcgg
    18301 tgtgcctgcc catatcaaag gctatcttta tttgcgtgaa gccatttcca tggtgtataa
    18361 cgatattgaa ctcctcggca gcatcacaaa agtcctttat cccgacatcg ccaaaaaatt
    18421 caacacgacc gcaagccgtg tagaacgggc catccgccac gccattgaag tcgcatggag
    18481 caggggaaat attgattcca tttcttcact gttcggatat acggtaagca tgacaaaagc
    18541 aaaaccaacc aactcagagt tcatcgcgat ggttgctgac aagctgagat tggagcataa
    18601 agcttcgtaa cgcaagcctt tggctaaatg tctttttgcg ccttctattc cgtgcatgaa
    18661 cgcggaagag aaggcgtttt gagattttgc tgacgaaaac aatgggaacc actcacgccg
    18721 gtacttgttc tatacataaa tacgggaact gccgtctata cgtataatac cggagctgat
    18781 attttaatga ttttgccgtc tctgaaataa aagcggggga tgcggcggct taacacagac
    18841 aggacttcgt agctgatcgt accgagcatt tcggcaattt catcaacgga aatctcggct
    18901 ccttgttgtt tgccgtagat gacgacttct tctccttgtt tgccctcatt ctcacctaaa
    18961 ctgaccatta tcatatccat tgtcactctc cccgccaccg gcacccgtct gccgcggtgc
    19021 agaataaacc cgcggttgga cagggcgcgg gagtaaccgt cagcatagcc gatcggaatc
    19081 gtcgcgatga tttcacccgg ttcggcgata tatgtggcgc cataactgac ggtccgggga
    19141 tctgtcacca tagctttcac ataagcgata cgcgccttta aacttagtgc gggtgtgaga
    19201 tccacgaggt tcagttcctt tatcgaggcg gacggatata aaccatataa cccaatacct
    19261 aaacggatca tgtcggcgct gaattccggg aatgcgatag cggcggctgt attgcacata
    19321 tgcacggtag gcagcgtaat gtcttgattt tttaaaaagc ggagaaagct gataaacttt
    19381 tcgtgctgca gcatcgtcag ctcagtgtcc ggttcatccg ctgttgaaaa atgtgtaaag
    19441 atgccatccc atgacaggta tgtactcgac ttgagcgctt tcaccactgc taaaagatct
    19501 tcttctgtgc gcacacccag ccggcccatt ccggtatcca cattgatatg aatggacagc
    19561 cgtttcgact ctgcttcttt ttccaatatc cgattcgctt ttttgatcca gctgacctga
    19621 aacgctgata atgtgatgtt ccaaacggca gattttttca cacagctgag agctgtgaag
    19681 ccgagcacaa gaataggcgc tttaattccc gctctccgta acacaattcc ctcttcgacg
    19741 ctggcgacag caagctcgct cgccccgctt tccagtgcct gccgcgctac ttccacagag
    19801 ccgtggccat aagcgttcgc ttttacgacg gccataattt tagacgtatt cggaatatgg
    19861 cggcggatcg cccgtacgtt cttttttatc gcatcaaggt caacttcaat ccaaacttcc
    19921 cggcaaagtt ttttcatcac gattccttct ttccttaatg agattcagta ctcatgcttt
    19981 caatctgcat tctattcatc tttaactgaa atcattcaaa acatgagaag gtgaccgctg
    20041 atgtttaaaa tcaagttttc gggaaagcat gcgcctgctt tatttatgca gtaagggctg
    20101 cttggcagcc cttacaatga ctttacaata ttctgatctg aaaattgatg ttcaaacatt
    20161 ttggactggc ttacagcatt gttttgaatg acaatgccga tatttccccc tccggcaccg
    20221 aaaacggttt ttgatgcagt cagcggactg atggatatgg cgccgccaac attgacaact
    20281 ccgtttcctg atacgttgtt tatcgtaatc gggcaaccgc tcattctatt ttttctcctt
    20341 tctctcacag tctactatct atatgtacgc tgtgatatgg aataagatta aacaaaacgg
    20401 caaaaagaat ccggctgctg ccagccggaa agggagggaa atacggatat cataatgttt
    20461 tcgttacatt ttgatcagag tattgagagt ttgaagattg agatgtgctg gattgattca
    20521 tttgcaggac catacctgta tttccccctc ctgagccgta gacggttttt gatacggtta
    20581 aaggacttat cgaaaacgca ccgccgacat tgacaacccc gtttccggaa agactgttaa
    20641 tcgtaatagg gaaaccagcc atcatatacg gtctcctttc tattaatcta tttactatat
    20701 gtacgctgtg tgttggaaat aggagtaaac aaagcggtaa aaacttgtga atcaaaaaaa
    20761 ctgccggaca tccggcagtt ttttagtcta cttttcaaac ggcacccagc cgcctgtatt
    20821 ctgaatcatt tcccataacg gttcaggaag tcggtattta tcaatttcag atgcctgaat
    20881 ggctttttcg a
//
