LOCUS       NZ_BORO01000012        22313 bp    DNA     linear   CON 15-SEP-2024
DEFINITION  Oceanobacillus sp. J11TS1 sequence12, whole genome shotgun sequence.
ACCESSION   NZ_BORO01000012
VERSION     NZ_BORO01000012.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Oceanobacillus sp. J11TS1
  ORGANISM  Oceanobacillus sp. J11TS1
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Oceanobacillus.
REFERENCE   1
  AUTHORS   Okamoto,M., Kumagai,M., Kanamori,H. and Takamatsu,D.
  TITLE     Antimicrobial resistance genes in bacteria isolated from Japanese
            honey, and their potential for conferring macrolide and lincosamide
            resistance in the American foulbrood pathogen Paenibacillus larvae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 118757)
  AUTHORS   Okamoto,M., Kumagai,M., Kanamori,H. and Takamatsu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2021) Contact:Daisuke Takamatsu National
            Agriculture and Food Research Organization; 2-1-2 Kannondai,
            Tsukuba, Ibaraki 305-8602, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.2
            Genome Coverage                   :: 1141x
            Sequencing Technology :: Illumina MiSeq; Illumina NovaSeq 6000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018333215.1-RS_2024_09_15
            Annotation Date                   :: 09/15/2024 08:23:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,037
            CDSs (total)                      :: 3,937
            Genes (coding)                    :: 3,848
            CDSs (with protein)               :: 3,848
            Genes (RNA)                       :: 100
            rRNAs                             :: 9, 4, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 4, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 32 of 89
            Pseudo Genes (incomplete)         :: 55 of 89
            Pseudo Genes (internal stop)      :: 14 of 89
            Pseudo Genes (multiple problems)  :: 12 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:11:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 60031
            Orig. end                         :: 82344
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BORO01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22313
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22313
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22313
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12313](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12313)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1057..1073
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.13"
                     /tool="antismash"
     misc_feature    1098..1111
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 26.23"
                     /tool="antismash"
     gene            complement(1976..2272)
                     /locus_tag="KI343_RS11145"
                     /old_locus_tag="J11TS1_22620"
     CDS             complement(1976..2272)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016133740.1"
                     /locus_tag="KI343_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22620"
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_212926500.1"
                     /transl_table=11
                     /translation="MAGQIRMSPEELQAKAKRYGQGSEQIDQVLTNLSNLQDELRGEWE
                     GRAFDQFEVQFRQLEPKVKEFSQLLLDIQDQLTKTAEAVAQQDEALSRNFGLS"
     gene            2576..3832
                     /locus_tag="KI343_RS11150"
                     /old_locus_tag="J11TS1_22630"
     CDS             2576..3832
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028091.5"
                     /locus_tag="KI343_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22630"
                     /product="DUF5068 domain-containing protein"
                     /protein_id="WP_212926501.1"
                     /transl_table=11
                     /translation="MIIGSSSKEINQEENEKEEPKDTEQDEEGNNEDTSSGGADSEQKE
                     NTADEKQTETSTNSNFDSLVAWMEEETEGTAAPLFENDETQTHEMEDVTVTLNAYQLVE
                     LKDIHTDFSIPFDDQTDGGVLLTEFTVKNDSDQDLYYTPDYYVNYFGGNKTTGINRNLI
                     PLDEQLSDMISVPNEQLLEAGKEYTGYLAHSFGEEQLEGILEEGNVTIEISTPFTDAEE
                     VSKEFTVGQSTELTLPLTDESAEKSAKVESEDFYQDKISKDNMGDKKMIEQEDGIGESD
                     ELGDVTITLDGYQFVDFTPNEYEADRFEDPDNLVVATVRFEIDNQGDQEIGMDNTSSRI
                     FLNDGTQYLRNESFLSPYEYEENIAAGEKGELLQTFLLDKEMYEKIWKDKSIEIEIGPM
                     NNLDYEDISKGHVVTFDLK"
     gene            complement(4211..4663)
                     /locus_tag="KI343_RS11155"
                     /old_locus_tag="J11TS1_22640"
     CDS             complement(4211..4663)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038335.1"
                     /locus_tag="KI343_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22640"
                     /product="YrhA family protein"
                     /protein_id="WP_212926502.1"
                     /transl_table=11
                     /translation="MWQSKLNEIKREKKLYEEEINIGAVEKEISDFEKKVLEEFKCKLP
                     EDYKDVLRIINGIEFNGFILYGIDEEILKDKPNQQINGFLELNHIWHENVEQKKYLFLG
                     ESNISWYVYDLKSRKFLELDNPSGEKIGVFKNFNELFTNLLEDALS"
     gene            complement(4745..5632)
                     /locus_tag="KI343_RS11160"
                     /old_locus_tag="J11TS1_22650"
     CDS             complement(4745..5632)
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI343_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J11TS1_22650"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_212926503.1"
                     /transl_table=11
                     /translation="MTEEMGLKRSIKWSGYQAQHALRAALGPLMSVPGIRIAGQTKTLV
                     RNAESVTNATRSAVAKGVNTAITVKEGANTAANWGALRFRSLGNAIQNRAVTATDNMVE
                     GVKKGTNQLKEGYEVLKSGLQPKMATTTVHVVSDTGAESFAYREAGESVRLEQWKRVAE
                     GSVGEGSNSINNFTWKLRGKDVTLQNIQTVNIEYIKRNAEELNHLRNEFNRTIRKDFLK
                     NLGENTDYLKNAGFSKTDILKLQNGRVPDGWQVHHKIPLDGGGTNSFDNLVLIKNEPYH
                     KVITNIFKTVFQES"
     gene            complement(5641..5883)
                     /locus_tag="KI343_RS11165"
                     /old_locus_tag="J11TS1_22660"
     CDS             complement(5641..5883)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI343_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J11TS1_22660"
                     /product="hypothetical protein"
                     /protein_id="WP_212926504.1"
                     /transl_table=11
                     /translation="MLNKSSIRIAQIENAATEERSLGVVPNDGSQTFHFFENTAKNAVN
                     AVMKSDMFSGTNSISVDNRIIPGASGVFQVEILLD"
     gene            complement(6124..6552)
                     /locus_tag="KI343_RS11170"
                     /old_locus_tag="J11TS1_22670"
     CDS             complement(6124..6552)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006095340.1"
                     /locus_tag="KI343_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22670"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_212926505.1"
                     /transl_table=11
                     /translation="MSILPERLDEVLGEEIYKREDSNLVKDALIRLDVYVSETFQKFYI
                     QYAGPFWEEHVPFELLDIVDEENNIESYTLFSRKEHGFPKQYLVLSEMSANAVLVLDTV
                     PDKVYTVNFEGGDELLLKGELKETWSSFFEFLKAYFNC"
     gene            complement(6707..6880)
                     /locus_tag="KI343_RS20130"
     CDS             complement(6707..6880)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI343_RS20130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244856888.1"
                     /transl_table=11
                     /translation="MVRTKGAKKGHGLTNAEASAKYGLAPILDDTGIVATLHHSQQKGV
                     GPLYEASTRYVS"
     gene            complement(7636..7818)
                     /locus_tag="KI343_RS11180"
     CDS             complement(7636..7818)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI343_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_212926506.1"
                     /transl_table=11
                     /translation="MINKLPISVRQVENTAMEEKSFVVVSNDGRQTFNFFENTTRNAMD
                     AVKNSDSFVGLVEVI"
     gene            complement(8125..8580)
                     /locus_tag="KI343_RS11185"
                     /old_locus_tag="J11TS1_22690"
     CDS             complement(8125..8580)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657443.1"
                     /locus_tag="KI343_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22690"
                     /product="immunity protein YezG family protein"
                     /protein_id="WP_212926554.1"
                     /transl_table=11
                     /translation="MEEFEAKFSELQADMVSICMEYVENRADKIYVYASCERNLISSKF
                     FYLINNKLVKSHKLNDALKQGEKDYDVSLDRGFMVLDIINEDIEKIKKICEEYKKDMPT
                     EMKLIYDVRSGKFKAEYKYDFVYTDKDHKTASDIADEWFEEIKSNNI"
     gene            complement(8600..8758)
                     /locus_tag="KI343_RS20135"
     CDS             complement(8600..8758)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025298.5"
                     /locus_tag="KI343_RS20135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="WP_244856892.1"
                     /transl_table=11
                     /translation="MEDKCARALKETPPKKVTVDVEIIYDKNNLRPEKFNVKYTIDGEP
                     YSEVFLN"
     gene            complement(8748..9038)
                     /locus_tag="KI343_RS20140"
                     /old_locus_tag="J11TS1_22700"
     CDS             complement(8748..9038)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025298.5"
                     /locus_tag="KI343_RS20140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22700"
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="WP_280530131.1"
                     /transl_table=11
                     /translation="MILNFSLINIRYQTGEYDYFYETDNLGRISKFETDNLQLTEREAR
                     LPHSRNTPGKIKGKDHGGHIVADRFEGSSKYDNLVSMLLDINLKKVQRDRG"
     gene            complement(<9016..9255)
                     /locus_tag="KI343_RS11195"
                     /old_locus_tag="J11TS1_22710"
                     /pseudo=""
     CDS             complement(<9016..9255)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003728383.1"
                     /locus_tag="KI343_RS11195"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22710"
                     /product="SMI1/KNR4 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKYSYLASNVNNSFYSVSIEEIRDVEESLKLKLPKELVEFYLEVG
                     YGFIKGSKYNVNRIMSPKSIRDFRLKQNDFEFFPN"
     gene            complement(9258..>9392)
                     /locus_tag="KI343_RS20145"
                     /old_locus_tag="J11TS1_22720"
                     /pseudo=""
     CDS             complement(9258..>9392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391809.2"
                     /locus_tag="KI343_RS20145"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22720"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="NIIENTFGGEHEWWNIHLARFPNEHQASIHGVGSPANRIFKGGK"
     misc_feature    complement(9560..9574)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.94"
                     /tool="antismash"
     gene            9587..9847
                     /gene="tlp"
                     /locus_tag="KI343_RS11200"
                     /old_locus_tag="J11TS1_22730"
     CDS             9587..9847
                     /codon_start=1
                     /gene="tlp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012811641.1"
                     /locus_tag="KI343_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22730"
                     /product="small acid-soluble spore protein Tlp"
                     /protein_id="WP_212926508.1"
                     /transl_table=11
                     /translation="MTNPKPKPDNRADNVEKIQNTIDHTMQNMDEAEDYVKAHAEEISS
                     QEKQKIKNKNERRRETIDGLRDEIKDEANYASQNLDQNELE"
     gene            complement(10001..12313)
                     /locus_tag="KI343_RS11205"
                     /old_locus_tag="J11TS1_22740"
     CDS             complement(10001..12313)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018932486.1"
                     /locus_tag="KI343_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22740"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_244856889.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-43, bitscore:
                     140.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLMGKDYFQMMQEQAKNYFHLLRAQVHQEDFAATLIESLQQYQQA
                     KKKSLINTDKWKQQPSNLFISQLAKMGQLDSYLFRSVSYIYFRDLGRDITTESMRRRIA
                     DITEGIKHYLDGKQQHVSFHMAELYQFAEKESLEPVFFWVTDKLKYISAILPEGFDKNE
                     AKRKIIKIIAGVIIHEIEELKDETSAQVRRQQLDQAVRIGYYYGLTYPLIDDVLDADVL
                     TEAEKKAFAYFIRQTLLTGEVIPIKASDWQENHWEFISAVYDGLSEAFTYLKACQPIER
                     NRDFLDNAYLFFEGQEQDRQKQLDNSSYTNEQLYVPVILKSASSRLIVRSFRAFSKDDK
                     IEKNMFHYGIYNQLADDLADFDEDLANRSVTPYTYFVTHHHQNQNVMNPFAMYWSVIYY
                     FVHTIYGGKPEIRDIILDRAINGLKRLKQRLGKERYQAFMQQFSFDTNFDKTLEKVINR
                     SQNVAFFDKWIRDQFLDTLRQNEQSKEQFVSKMKEIKEQLEGHLSLESIENTLEQAAEY
                     SLGGNAKRLRPIMTWIMAKEGFNLPDQMILPLAKSVEYMHTASLIFDDLPSQDNASTRR
                     GKQTLHEKYNHAVAELTGLWITQRAVEEQTTIKHADPERVLELIAYSTRTTQDMCKGQL
                     LDLNAKEKQLTLESLKELSVYKTSLGFEAALMMPLILAGASADRKQAVKHLAYHAGIAF
                     QIKDDLLDLTGDAMLLGKQPGQDQRNKSATFVSILGQEQAQKEMWKHYLAARDYLTMLP
                     DVPFFYQLLDYLIFREH"
     gene            complement(12809..13423)
                     /locus_tag="KI343_RS11210"
                     /old_locus_tag="J11TS1_22750"
     CDS             complement(12809..13423)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01470.1"
                     /locus_tag="KI343_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22750"
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="WP_212926509.1"
                     /transl_table=11
                     /translation="MRIPILFEMTNKTVIAVGGGAVAAKKLKHFIGVGADITIIAPSLH
                     PALQQLYENGQIQWQKREVREEEQFDSLLLLLMTEKKELNQSLYEKKLPHQLVYVANDA
                     QKSDIHFPATLQKGPLTMALSTDGASPAYTKQLKNRLAEQLPADIEGDLYFLKQARKII
                     LADPSLAEQKKQLLQQISTEEFLRQENRDQLLEAMLEDARQ"
     misc_feature    13417..13435
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            complement(13428..14198)
                     /locus_tag="KI343_RS11215"
                     /old_locus_tag="J11TS1_22760"
     CDS             complement(13428..14198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877513.1"
                     /locus_tag="KI343_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22760"
                     /product="sirohydrochlorin chelatase"
                     /protein_id="WP_212926510.1"
                     /transl_table=11
                     /translation="MQAILYIGHGSRVQQGNKELLAFVEKAKKSNPHIKIQETCFIELA
                     SPTIQTGVDNCIWQGATQIAVVPVLLLCAGHAKQDIPKEIDQAKNRYPDVTFSYGKVMG
                     VDPAMIDVLNARLEMGGLATKSQPPVYEERESVSVLLVGRGSSDPDANSDLTKIARLLW
                     EAAPVREVATCYLAATHPTLDEGLEQMVESAHPRVYVVPYLLFSGVLMRELRQKLDELS
                     ASTDKQFILCPYLGFDDQLVDVLVDRVNALLEER"
     gene            complement(14280..15761)
                     /gene="cobA"
                     /locus_tag="KI343_RS11220"
                     /old_locus_tag="J11TS1_22770"
     CDS             complement(14280..15761)
                     /EC_number="2.1.1.107"
                     /GO_function="GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012958294.1"
                     /locus_tag="KI343_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22770"
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="WP_212926511.1"
                     /sec_met_domain="TP_methylase (E-value: 1.9e-45, bitscore:
                     148.4, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQGCVYLIGAGPGDIGLLTLKGYTYLKHADVVLYDRLVNPLLL
                     EHASPQAEMIYCGKMPKKHILRQEAINALLVQHGLEGKNVVRLKGGDPSVFGRVGEEAE
                     ALKNAGVPYEIVPGITAGIGAAAYAGVPVTHREHSLSFAVITGHDKSPAGEPLIDWKAL
                     ANGIDTIAFYMGIGNLPYIAEQLTSHGRSSETPVLLIQWGTTGKQRTLLGSLGTIVEQA
                     KADHFKNPAIILVGEVSKLKEGESWFESKPLFSQHLLLGRSSEEMSEIGARLRDKGAEV
                     FEFPRMQIKKQLLREADIPVHHDLLFLSPASVEVFFASLQANNMDIRSIQGEFYGLSKK
                     TVKALESYHCLARQISERDSNASRLVILGDAGWIGKEELLSFAEEQDFIVTHAYDRVPQ
                     TEQTFRRLRDEERMDTIIFPNARSVETVTAGLQACGESPEMISSYTRIICFGEKSKQAA
                     VRAGYTVHTVLAQPTEEALLEVLLKKEALLEAALS"
     gene            complement(15914..17635)
                     /gene="cysI"
                     /locus_tag="KI343_RS11225"
                     /old_locus_tag="J11TS1_22780"
     CDS             complement(15914..17635)
                     /EC_number="1.8.1.2"
                     /GO_component="GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009360921.1"
                     /locus_tag="KI343_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22780"
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="WP_212926512.1"
                     /transl_table=11
                     /translation="MTNDKVIPTQDGPPSDVERIKRESNYLRGTLSETLEDRLSAGIPD
                     DDNRLMKFHGSYLQDDRDLRTERQRQKLEPAYQFMVRVRVPGGVATPEQWLVIDELARE
                     YGNHTIKLTTRQAFQMHGILKWNMKKSIKRINEALMDTLAACGDVNRNVMCNPNPDQSE
                     VHAEVYEWSKVLSDYLSPRTNAYHEIWLDGEKVVDSKENEEVEPMYGPVYLPRKFKIGL
                     AVPPSNDIDVFSQDLGFIAILEDGRLQGFNVAVGGGMGMTHGDTNTYPQLGRIIGFCRP
                     EQITDVAEKIITIQRDYGNRSVRKNARFKYTIDARGLDWLKSELTERLGWQLEEARDFH
                     FDHTGDRYGWVKGTKNHWHLTLFIQNGRIQDKDDYQLMTGLREIAKIHTGDFRLTPNQN
                     LIIGNVSSEKKEEIAELVAQYGLADGKEQSALRRNSMACVAFPTCGLAMAESERYLPAL
                     LEKIETMLEEEGLRDEEIVIRMSGCPNGCSRPALSEIGFIGKAPGKYNMYLGAGFSGQR
                     LNKLYRENIGEKEILETLQPIIRHYAKERLDGEHFGDFVIRTGYVKAVTSGLDFHD"
     gene            complement(17656..19482)
                     /locus_tag="KI343_RS11230"
                     /old_locus_tag="J11TS1_22790"
     CDS             complement(17656..19482)
                     /EC_number="1.8.1.2"
                     /GO_component="GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019715721.1"
                     /locus_tag="KI343_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22790"
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="WP_212926513.1"
                     /transl_table=11
                     /translation="MQFQVKNSPFNEEQVDLLNRLFPTLTETQQIWLGGYLSAVKNVNQ
                     SAQVTDAALAGPQSANEAEAAPVEVTVLFGSQTGNCQNLATGLSEQLEEKGMKVTLASM
                     NDFKPNKLKNIENLLVIVSTQGEGDPPDNAIQFYEFLHGRRAPKLEKLNYSVLALGDSS
                     YEQFCETGRKFDERLAELGGTRLADRTDCDLDYDEPAAEWFESVLNKLSESQVSVQVQP
                     DAIVSAAAESSTFSRTNPFEAEIYENINLNGRGSNKETYHMELSLEGSNLQYEPGDSIG
                     IYPENDPEMVDALIKEAGWKPNELVPINKKGEEVLLQEALQKNFEITVLTKPLLQKVAA
                     FTQNPELQHLLEPGNEAAVTEYIHGRDLLDLIRDYGIAGAPAKEFITLLRKMPPRLYSV
                     ASSLKANPEEVHLTIGAVRYETYGRERNGVCSVQCADRKEPGQTLSIYVHNNPNFKLPA
                     DPSTPIIMIGPGTGIAPFRSFVEEREVMEAEGKSWLFFGGQHFVTDFLYQTDWQRWLKS
                     GVLTKMDVAFSRDNAEKVYVQHRMLEQSRELYEWLEDGATVYVCGDEKHMASDVHDTLV
                     TIIEKEGNLTTDEAQTYLDNMLQEKRYQRDVY"
     misc_feature    complement(19499..19515)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.54"
                     /tool="antismash"
     gene            complement(19559..20179)
                     /gene="cysC"
                     /locus_tag="KI343_RS11235"
                     /old_locus_tag="J11TS1_22800"
     CDS             complement(19559..20179)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019395085.1"
                     /locus_tag="KI343_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22800"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_244856890.1"
                     /transl_table=11
                     /translation="MKQEAEHIVWHDTAVQKKDRQQRNGHGSCILWFTGLSGAGKSTLA
                     NALEHRLFEQGLNSYVLDGDNVRHGLNQGLGFSEEDRKENIRRIGEVAKLFIDAGFIVC
                     TAFISPFAEDRNRVRALVEENEFVEIYVRCALEACEDRDPKGLYKKARTGEISNFTGIS
                     SPYEEPERPELVVDSDQLSIDACVDKIIAFLKERNHLPVEADI"
     gene            complement(20230..21306)
                     /locus_tag="KI343_RS11240"
                     /old_locus_tag="J11TS1_22810"
     CDS             complement(20230..21306)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881205.1"
                     /locus_tag="KI343_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J11TS1_22810"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_280530133.1"
                     /transl_table=11
                     /translation="MLIAVAFIIALFFAMNIGASGTVASMGPAYGSGAIPKKRVAMILV
                     GVFALLGALSGGEVVRTIGQGIVPGEVLDIEIVVIVLGAACLTLFIANMLGIPLSTSEV
                     VVGAIVGVGVAYQSLFWDWLLVIVSFWLITPFIAFFIGLIFGKWIRYAENRWKDLTGTG
                     KWRKPLAFLLIAAGCIEAYAAGMNNVANAVGPLVGVGLLDVTTAVLLGGIFVSLGAVLL
                     GGRVMETNGKKITQLSLLQGSAVSLTGGSLVITASVFGLPVPLTQITTSAIVGIGTAEK
                     GFHMWQQSIIKQIIKVWIVSPVFSLVMSYGLILLFKQADYYSLFVITSVFIATVGFYSL
                     YLSTRAERRSTYDEGGGI"
     misc_feature    21752..21769
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.75"
                     /tool="antismash"
ORIGIN
        1 cggttccaaa acggaagctg tcattgcgga ttccgattca tctatatctt taatatctgc
       61 taaatctact tcccaactcc atccaacagg ctgaaaaaca tcgatttcag atccggcgtc
      121 tctcaatttc aggttaaatt gaacggttaa ttcccctgca tccaaaggtg gaagtatgat
      181 attcccacca ttatattcat aatcgacttc tttattattt aaagtgagcg ttaaaccact
      241 ctctttaaac gcctcaggga tttttaattt aaatattgaa cctggttctt caatttcttc
      301 aggaatgtta accgtatcct tcactaccac cccattgtta gctaaatctg ttttaatctc
      361 ttgtactagc tgaggtaaag ttttcttatc attagcgtat tttggttcat atccaaactc
      421 tttattatac ttatccgtta ctttcttaac attttccaat tcggtaacgg tctgctccga
      481 taaaccaaga ctcctaattt cattcatatt gagatatggt aacttattta tctgattttg
      541 tatgctttgt tgcgcttgat tgtctgctgc atcaaacagt atgctcaaat taccctcttc
      601 gccatctaaa gctgcttcaa aaatgcctga tagcctattt ttcactctgg aattcatatc
      661 caaatccaat ttttcttgca aatacatatc caaatttgta atttgttcac ttgtgttttc
      721 taactggctt tgtatcatta ctgcatctgt accagcagtt tgtctatcct ctttttcctg
      781 ttgaagctga ttattaattg cttcgtttgc tgcctctaat tctactaatt gctgtgatat
      841 atcttcatta cttaattggc tgctaaagtc gtttagctga cctaaaaagt cccttgataa
      901 atggttattt gtatctttta atgcaatata atcttccata gctgataaat aacttcgatt
      961 tgtttcagca tggctattta aactatcatc aaacgtgtct aatatttctt ctaagctact
     1021 aaaactctct attgatgctt ctgtattatc ctgtactgca ctaaaacggt ccgtataaga
     1081 actgagtggg tcattgatag aattattata agtagaggta tgtgctgctt gtctttccac
     1141 aatggaacca atgttgtctt gtgcattttg taagttactt atgatgcttg caaaataaac
     1201 atcgataatt cgccggttta cgtcattcaa tatttcacta gctgtctttt ctgcttcaga
     1261 ttgtatcctt tgattgcctg atgcattaat tttataattt aatgacactt gttccggtga
     1321 ttccgaatcc atagataacg cttttactga aaaatcattg ggaataataa tcatcatatc
     1381 gtatgtattg ttttcaagtc cgctttcagc aacaccgcga ctaacaacgt accagtcatg
     1441 cgactcatcc ttgtccatac ttttaataaa cgtttctcca aaggataact cattaccatt
     1501 aaaagttgca ccatcgtcct cgtttacaag tgctatgttc attgccatta cttgctcttc
     1561 ttttcctttt tccgttttct tcgtggaaac ttggttaaaa ccaagatagg acaaccctga
     1621 agcaagaaaa agcatcaaaa ttaagaacaa aagaattcgc ttatttagct ttttcactta
     1681 ttttcaactc ctgcacattc tttaaaaaat caattatata aaataaagct tcattctgtg
     1741 gagattattt ttcactccac tccctcaagt gattctagga gttagcctcc gttaactact
     1801 atcaaaatag atttattatt cactgctttg cggcgggagt tttaccgata attctccctg
     1861 ataaatcctt agacatgttt tttacctcta tatatctatg aaataaacat gagccacaca
     1921 acaatcgtcg cgcggctcaa gatagtgatt attgaaaata ttacaaattc cttaattaac
     1981 taagaccaaa attacgtgat aaggcctcat cttgttgtgc cacagcctca gcagttttag
     2041 ttagctgatc ttgaatatca agcaacaatt gagagaattc tttaaccttt ggttctaatt
     2101 gtctgaattg aacttcaaat tggtcaaaag cgcgtccttc ccattcccca cgtaactcat
     2161 cctgtaagtt agataaattc gtcaaaactt ggtcaatttg ttctgatcct tgtccataac
     2221 gttttgcttt tgcttgcaat tcttccggac tcatacgtat ttgtcctgcc atcattaacc
     2281 atctccttta tcaatataag tagtaattca agtgaaaagc ttcctataaa attattatag
     2341 agcaaacacc aaagcttatt ttccaaggtg ttagttgtca gtataataat agcgttttct
     2401 cttgtcaaca tgctattaga aggagatttt aatttaagcc aaaagaagtg tgagtataga
     2461 atactattaa tgtaattatt taggaaaaat attggttttt agcaatagaa gacaattttc
     2521 aaagattact ttttgatagt tttatacata agaatcaata ggaaaaatag ttggtatgat
     2581 tatcggaagt agttctaaag aaataaatca agaagaaaat gagaaggaag aaccaaagga
     2641 cacagaacaa gatgaagaag gaaataatga agacacttct tccggtggag cagattccga
     2701 gcaaaaagag aatactgctg atgaaaaaca aacagaaacg agcacaaatt ccaattttga
     2761 ttctttagtt gcttggatgg aagaggaaac agaaggtact gcggctcctc tctttgaaaa
     2821 tgatgaaact caaacacacg aaatggaaga tgtaacagta actttaaatg cttatcaatt
     2881 agtagaatta aaagatatac atactgattt tagtattcct ttcgatgatc aaacggatgg
     2941 tggtgttctt ttaacagaat tcactgtaaa gaatgattct gatcaggact tatactatac
     3001 accggattac tatgtgaatt attttggtgg aaataaaact actgggatta atcgaaatct
     3061 gattccactc gatgaacaat tatctgacat gatatctgtc cctaatgaac aattgcttga
     3121 agctggtaaa gaatatacag gttatttagc tcattctttt ggtgaagaac aattagaagg
     3181 aatactcgaa gaaggaaatg tcacgataga gatttcaacg ccatttacgg atgctgaaga
     3241 ggtctctaaa gaatttacgg ttggccagag tacagaattg acgctgccac taacggatga
     3301 aagtgctgaa aaaagcgcta aagtagaaag tgaagacttc taccaagata aaatcagtaa
     3361 agataacatg ggcgataaaa aaatgattga gcaggaagat ggaattggcg aaagtgacga
     3421 attaggtgat gtaacgatta cattggatgg ttatcaattt gttgatttca ccccaaatga
     3481 atatgaagca gatcgttttg aagaccctga taatctagta gtagctactg taaggtttga
     3541 aatagataat cagggtgatc aggaaattgg tatggacaat acttcatcac gaatatttct
     3601 taatgacggc acacaatatt tacgaaacga gtcttttctt agtccatatg agtatgagga
     3661 aaatattgcc gccggtgaaa aaggagagtt attacaaact ttcttattag ataaagaaat
     3721 gtatgaaaaa atttggaaag ataaaagcat agaaattgaa attggtccaa tgaataactt
     3781 agattatgaa gatatttcta aaggacacgt agtcactttc gatttaaaat aagtaaaaag
     3841 actagtgtag catttctgaa atagttgctc ttggtgtcca ctctaaaatc aaaaaaggta
     3901 aataaaatcc gcatgaacac tgaacttttg gtaaatttat gatactaacc aaatctacca
     3961 aaaagaacgt gttatcatgc ggaaaaacta ccttggcgca cttttctttt ttgtgtggtc
     4021 aaacagacta ggaaatgaaa ccaaattctg ctctttgata taccatagat gcccgaatag
     4081 gataaaagat tttgaaagaa tttctatgat aaatgaccat atttgtggtc gcgagtatca
     4141 tctacatata tgtcctagca ccttctcatc agaagctatt aatataagaa actctttctt
     4201 ttctattaaa ttacgataat gcatcctcta ataagttagt aaataactca ttaaaatttt
     4261 taaatactcc aattttttct ccagaagggt tgtctagttc taaaaatttc ctgctcttta
     4321 aatcatacac ataccagcta atattacttt cacctaaaaa taaatatttt ttctgttcca
     4381 cgttctcatg ccaaatatga tttaattcta aaaacccatt aatttgttga ttaggtttat
     4441 ctttaagaat ttcttcatca ataccgtaca atataaagcc attgaattct ataccattaa
     4501 taattcttaa gacatcctta taatcttctg gaagcttaca tttaaactcc tccaatacct
     4561 tcttttcaaa atcagaaatt tctttttcta ctgcgcctat gttgatttct tcttcgtata
     4621 attttttttc ccgctttatc tcatttaact tactttgcca catacttctc actccttcag
     4681 tgttttggtg ggtaaattac tccgtctatt aatggccaat ccacattttt tatctgccct
     4741 gcgtttaact ctcttgaaaa actgttttga aaatattagt aattacttta tgatatggtt
     4801 catttttaat taatactaag ttatcaaagc tatttgttcc accaccgtct aaaggaattt
     4861 tatgatgaac ttgccaaccg tctggaaccc taccgttctg taatttaagt atatctgtct
     4921 ttgaaaagcc agcattctta agataatcag tattctcacc tagatttttt aaaaagtctt
     4981 ttcttattgt acggttaaat tcattcctta aatgatttag ctcttcggca tttcttttaa
     5041 tatattctat attaacagtt tgaatgtttt gtaatgtaac atcttttcct cttaacttcc
     5101 atgtgaaatt attaatacta ttagatcctt cacccacaga cccctcagca actcgcttcc
     5161 actgctccag ccgaacagat tcccctgctt ctctataagc aaaactttct gcacctgtat
     5221 cacttactac atgcactgtt gttgtcgcca tctttggctg aaggccagac ttaagcactt
     5281 cgtatccttc tttcagctga ttcgtgcctt tcttcacacc ttctaccata ttgtccgtgg
     5341 ctgtgactgc tctattttga atggcattcc ccaaacttct gaaacgaaga gctccccagt
     5401 tagccgctgt attcgcacct tctttgactg taatcgctgt atttacacct tttgctacag
     5461 cgcttctggt tgcgttagtt acactttccg cattacggac aagggttttg gtttgacctg
     5521 caatacgaat acccggtacc gacattaaag gtcctagcgc cgcccgtaat gcatgttgtg
     5581 cttgataacc actccatttt atagagcgct taagtcccat ttcttccgtc aagttttttc
     5641 ctaatctagt agaatttcca cctgaaaaac tcctgatgcc cctggaataa tcctattatc
     5701 tacactgata ctattagtcc cactaaacat atccgatttc atcacagcat tcactgcatt
     5761 cttcgccgtg ttttcaaaga aatggaacgt ttgcgaacca tcattcggta cgacccctaa
     5821 agacctttct tctgtagcgg cattttctat ttgtgctatt ctgattgacg atttgtttaa
     5881 catcgatgga catctgagtg gctagttctt tcctgatgga gttcccaccc tacaatatgc
     5941 cctagactcg aacgctccct actttcctat acatataaaa cagcctgaca caattagaat
     6001 atcagtgtca tccaggctta aaactgaaat attttaattt tcattgtcta ctttacagat
     6061 tccaatttat aataccaatt aagactttaa gtatctatga attatttttt tattgattca
     6121 taattaacaa ttaaaatatg cttttaagaa ctcaaaaaac gatgaccaag tttcctttag
     6181 ttcccctttt aaaagcagtt catctccacc ctcaaaatta actgtatata ctttatctgg
     6241 tacagtatcc agcactaata cagcatttgc tgacatttca cttaaaacta ggtactgctt
     6301 cgggaaacca tgttcttttc tagaaaagag tgtgtatgat tcaatattat tttcttcatc
     6361 tactatatct agtaattcaa aaggcacatg ctcttcccaa aaaggtcctg catactgaat
     6421 ataaaatttt tggaaagtct ctgacacgta tacatctagc cttattagag catcctttac
     6481 tagattgcta tcttcacgct tatatatttc ttctcctaga acttcatcta atctctcagg
     6541 caaaatactc atattatttt cctcctaaag cttcttctcc tcgtattttc caataattaa
     6601 tggaatctac tttttgaaat gctcctctag ttgttcctcc attggataaa atgggtttaa
     6661 ccttccctta aaaggatgta gtggagctct tttttcatta ctgatattat gatacatacc
     6721 tagttgaagc ctcatatagt ggtccaacac ccttttgctg tgaatgatgc aacgttgcaa
     6781 caatacctgt atcatcaagg ataggggcaa gtccgtattt cgcagatgct tcagcatttg
     6841 ttaacccgtg gcctttttta gcaccttttg ttcgaaccat attccactta atatctcctc
     6901 tttgatatac cttataggta aatcctgtgc catctttacc tgcattatac tctacactcc
     6961 gagtaatatt tattttacct tctcccagca caaggttccc atcaactcta tctatcctac
     7021 cttgactatc tgttgtataa ttgtatcctt ctttgagtac ggcggacgat ttttaccact
     7081 tgtgccatct tttttaccac cctttgcgga gaaatgtacc acttattgca gagctcttca
     7141 ccatacaata cagagacaag ccaatgaagt ggaataaact gtttcatgca tgatatagca
     7201 accattccac cacccttgac cttgtttgta tccgtggtag tggttttaat ggcggatgga
     7261 gaaaaagcag cctttaggac ttcatccgct caaataggta ccacggacaa tcacttctaa
     7321 gttccgctgg cggtcaaggg caagcagtta acactgtggt taatcagtgc ttattctcca
     7381 gttgaacagg tcattatagt catagatgga atattaggac ggcctatgat cagaaatggt
     7441 aaacccttcc acaaaaggtg gtaaaactct ccacattccg tggtaaaaaa gattgcaagg
     7501 gtggtacata ctgaatgcca tactcacctt ctttacttgt atacttaacg ttcggtttta
     7561 atacttttct tcgcccatct tttatataat gttctccata agggacttct ataattctag
     7621 gaacattatc taaatctaaa tgacttccac tagccccacg aaactatccg aattcttcac
     7681 tgcatccatt gcattccgag tcgtgttttc aaaaaagtta aaggtttgcc tgccatcatt
     7741 cgatacgact acaaaagatt tttcttccat tgcagtattt tctacctgac gtaccgatat
     7801 tggaagttta tttatcaccg cctggatgac actatctaca tccctacatc cattaccgct
     7861 cctattggtt ctttgccaat cactgcaaca ccattttgca aactattctt taattgctga
     7921 acccgactta cgctagtttt tgagcctctt ttactcgatt ggccacacta agatcgttat
     7981 ctacctgtac attcaatttc aaatgcttaa taagatagaa tacaaggata aaaacaacct
     8041 agcactattc aaaatcggta ctaggctgcg gtaaaaacat ttttaatttt aattaatgct
     8101 attcctattt tatttcattt atacttaaat attattactc tttatttctt caaaccattc
     8161 atcagcaata tcacttgctg ttttatgatc cttatccgta taaacaaaat catatttata
     8221 ttctgctttg aattttccac ttctgacatc ataaattaat ttcatttccg taggcatatc
     8281 ttttttgtac tcttcacata ttttttttat tttttctata tcttcattta tgatgtctaa
     8341 caccataaac cctcgatcca aagatacatc ataatctttt tcaccttgct tcaaagcatc
     8401 gttcagttta tgacttttta caagtttatt attaattaga taaaagaatt tactagaaat
     8461 cagatttctt tcacacgaag catacacata tattttatct gctctatttt ctacatattc
     8521 catacaaata gataccatat ctgcttgtaa ttcactaaat ttagcttcaa attcctccat
     8581 cattatatca ctccttaaat caatttagaa aaacttcaga atatggttca ccatcaattg
     8641 tatatttgac attaaatttt tcaggtcgta aattattttt gtcatatata atttcgacat
     8701 ctactgttac ctttttaggt ggcgtctcct ttaaagctct tgcacattta tcctctatct
     8761 ctttgtactt tttttaaatt aatatctaat aacattgaaa ctaaattatc atatttagaa
     8821 gaaccttcaa accgatcggc tactatatgc cctccatggt cttttccttt tattttcccc
     8881 ggcgtattcc tgctatgtgg taatctagct tcacgttctg tgagttgtag gttatctgtt
     8941 tcaaacttag aaattcttcc taaattatct gtctcataaa agtaatcgta ttcccctgtt
     9001 tgatatcgaa tatttattag ggaaaaattc aaaatcattt tgctttaacc gaaagtctcg
     9061 gatagatttt gggctcatta tacggttaac attatacttt gaacccttaa taaagccata
     9121 accaacttca agatagaact caactaattc tttaggtaat tttaatttta aagattcttc
     9181 aacgtctcta atctcctcta tagatactga ataaaaacta ttatttacat tagaagctaa
     9241 gtaactgtac ttcactttca ttttccccct ttaaaaattc tatttgctgg agaacctaca
     9301 ccgtgaatac ttgcttgatg ttcattagga aatcttgcta gatgaatatt ccaccactca
     9361 tgttctccgc caaaagtatt ttcaattata ttaagtaaat agtataaata tctttccaac
     9421 aataaattat gagggagtgg attgaatgac agagatgatc tccatccgtt acgactccac
     9481 agatattatc acccttcttt ctttataaaa attcataaaa tgatacataa aaaagaacca
     9541 tttagagaag ctatcattga attatcttaa aaaaggagag atagtgatga caaacccgaa
     9601 accaaaacca gacaatcgcg ctgataacgt agaaaaaatt caaaatacca tcgaccatac
     9661 gatgcaaaat atggatgaag ctgaagatta cgtaaaagca catgcagaag aaataagttc
     9721 gcaagagaag caaaaaatca aaaataagaa tgaaagacgc agagaaacca ttgatgggct
     9781 tcgagacgaa attaaagacg aagcgaatta cgcatcacaa aacttggacc aaaacgaatt
     9841 ggaataacag aaaagacttc agtcagtatt caagcaaatg attgaagaat aataaaaccc
     9901 ggataaaatt cacactctag tttgttctaa aacgtgaatt ttattcgggt ttaaatgttg
     9961 cagacccaaa gtgctgccta catcagttat tctatgagta tcagtgctcg cgaaatatca
    10021 gataatctag cagctgataa aagaaaggaa catctggaag catggtcaga taatccctag
    10081 ccgctaagta gtgtttccac atttcttttt gtgcctgttc ctgaccaaga atagagacaa
    10141 aagttgcact cttattccgc tgatcttgtc ctggctgttt ccccaacagc atagcgtcac
    10201 ctgttaaatc caataaatca tctttaattt gaaaggcaat accagcgtga taagctaaat
    10261 gtttaaccgc ttgcttccgg tctgcggatg caccagccag gataagcggc atcatcagtg
    10321 ctgcttcaaa accgaggctc gtcttataaa cggataattc ttttaacgat tcaagcgtta
    10381 actgtttctc ttttgcattt aaatcaagta attgtccctt gcacatatct tgtgttgtcc
    10441 gggtcgaata agcaattagt tctaataccc gctccgggtc tgcatgctta attgtagttt
    10501 gttcctctac tgcccgctgc gttatccaaa gtcctgtcag ttcagctact gcatggttat
    10561 acttctcatg cagcgtctgt tttccccttc ttgtggatgc attatcctgt gacggtaaat
    10621 catcgaaaat aagggaagct gtatgcatat actccactga ttttgctagt ggcagtatca
    10681 tctggtccgg taagttaaag ccttccttcg ccataatcca agtcataatc ggccgcaagc
    10741 gtttggcatt acctcctaag ctgtactctg ctgcctgttc taacgtattt tctattgatt
    10801 ccaggctgag gtgcccttct aactgttcct ttatctcttt cattttagag acaaactgtt
    10861 ccttagattg ctcattttgc cttaatgtat ctaaaaattg atcacggatc catttatcaa
    10921 agaaggccac attttgactg cggtttatta ctttttctag tgttttatca aaattcgtat
    10981 caaaagaaaa ctgctgcata aaagcttgat agcgttcttt acccagcctt tgctttaaac
    11041 gtttaagacc attgatggct cgatccaata taatatcccg aatctctggt ttccctccat
    11101 aaatcgtgtg aacaaaataa taaataacag accaatacat cgcaaatgga ttcattacgt
    11161 tttggttctg atgatgatgt gttacaaaat aggtgtaggg cgttacactg cgattagcta
    11221 aatcctcatc aaaatcagct aaatcgtctg ccagctgatt ataaattcca taatgaaaca
    11281 tattcttttc tatcttgtca tccttagaaa aagcccggaa agaacgcaca atcagccggg
    11341 aagaagctga ttttaaaatt acaggaacat acagttgttc atttgtataa ctgctattat
    11401 ctaactgttt ttggcggtcc tgttcttgcc cttcaaaaaa caaataggcg ttatctaaga
    11461 aatccctgtt gcgctctatt ggctgacaag ccttcaaata agtgaatgct tccgacaacc
    11521 catcatacac agcggaaata aactcccaat ggttttcctg ccaatccgat gcttttatag
    11581 gtataacttc accagttaat aatgtttgcc ggataaaata ggcaaatgcc ttcttttcag
    11641 cctccgtcaa aacatccgca tctagaacat cgtcaattaa cggataggtt aaaccataat
    11701 aataaccaat gcgaaccgct tgatctaatt gttgccttct tacttgagct gatgtttcgt
    11761 cttttaattc ctcgatctca tgaataataa cgccagcaat aatcttgatt atttttcgtt
    11821 tcgcttcatt tttatcaaag ccttcaggaa ggattgcaga gatgtatttc agtttatctg
    11881 taacccaaaa gaaaaccggc tccagggatt ctttctctgc aaattggtat aactctgcca
    11941 tatggaaaga aacgtgttgc tgtttcccgt ctaaataatg ctttatcccc tctgtgatat
    12001 ccgctatcct ccggcgcata gattccgtgg tgatatcccg gccaagatct cggaaataga
    12061 tataagatac actccgaaac aaataggaat caagctgccc cattttggct aattgggaaa
    12121 taaataaatt acttggctgc tgtttccact tatctgtatt tattaagctt ttcttttttg
    12181 cttgctgata ctgctgaaga ctctctatca acgttgctgc aaagtcctct tgatgtactt
    12241 gcgcccgcaa taaatgaaaa tagtttttcg cttgttcttg catcatttga aaataatctt
    12301 tacccattaa catgttccgt cctcatattt tttctaatta taacatgagg aacgaaaaac
    12361 gctcatttat tgagcaaaaa atttacttaa cctttacatt attaaataga gcgtagataa
    12421 ccttttagag ggtatatttc ttgaggttgg agcgcttttg gcttggggtg gagcggtttg
    12481 gctgaatctg gagcggttct tgcctggatt ggagcgattt aggatttcga gcggttttag
    12541 cctaggttgg ggttgagcgc tttcgctgga tttagagcga ctttggcctg agttggagcg
    12601 ctttaaccag gtttcgagcg actttgacct ggattggagc gctttcgctg gatttagagc
    12661 gactttgacc tggattggag cgctttggct ggatttcgag cgctttcaac ctaagttgga
    12721 gcgccttggc ctgaggtgat cagcagaact gatcaagtga tttctagcct ttgatcagtt
    12781 cttattttct ttttatttcc ggcatttatt actgtctggc gtcttcaagc atggcttcta
    12841 agagctgatc ccgattctct tgccttagaa attcttcggt tgaaatttgc tgcagcagct
    12901 gtttcttctg ctctgccaga gatggatcag caaggattat ttttctggcc tgctttaaaa
    12961 aataaaggtc accttcaatg tcagccggga gctgttcagc cagtctgttc ttaagctgtt
    13021 ttgtataggc aggactggca ccgtctgtgg aaagggccat ggttaatggg cctttttgaa
    13081 gtgttgcggg aaaatggata tcgcttttct gtgcatcgtt ggctacgtaa acaagctgat
    13141 gcggcagttt cttttcataa agagactggt tcaattcttt cttttctgtc attaacagga
    13201 ggagcagact gtcaaattgt tcctcctctc tgacctctct tttctgccat tgaatctgcc
    13261 cgttttcata caattgctgt aaggcagggt gaagcgatgg tgcaataatc gtaatatctg
    13321 ctccaacgcc tataaagtgt ttcagctttt ttgctgcaac ggctccccct ccaactgcaa
    13381 ttaccgtttt atttgtcatc tcgaaaagaa taggaattcg catcggctca cctttcctcc
    13441 agcagggcat tgacccggtc gaccagaaca tcaaccagct gatcatcgaa tcctaaatag
    13501 ggacagagta taaattgttt atctgtgctt gcagataatt catctaattt ctgtcgcaat
    13561 tccctcatca atacgcctga gaataacaaa tacgggacaa catatacacg gggatgggca
    13621 ctttccacca tttgttcgag cccttcatcc aatgtcggat gcgtggcagc aaggtaacag
    13681 gttgctactt ctcgcactgg agcagcttcc cataataagc gtgcaatttt ggtaagatca
    13741 ctattggcat ccggatcact gctgccgcgg ccaacaagta atacagaaac cgattccctt
    13801 tcttcataaa cggggggttg gcttttcgtt gcaagtccgc ccatttcaag gcgtgcgtta
    13861 agtacatcaa tcattgctgg gtcgaccccc atcaccttgc catatgaaaa tgtgacgtct
    13921 ggatatctgt ttttggcctg gtctatttct tttggaatgt cctgctttgc atgccctgca
    13981 cagagaagca ggacaggcac aaccgcaatc tgtgttgccc cttgccaaat acagttgtct
    14041 acgcccgttt gaatcgtcgg tgaagcaagc tcaataaaac atgtttcctg aattttaatg
    14101 tgcggattac ttttcttcgc cttttcaaca aaagccaaca gctctttatt tccttgctgt
    14161 acacggcttc catgcccaat atataaaatt gcctgcatgc aggttcacct tcttccatat
    14221 ttacctttca actctcaagg ctttcatacc ttgctatctc agtcgccgct cttctatcat
    14281 taggaaagag cagcttcaag caaggcttct tttttcaaaa gtacttctag caaagcttct
    14341 tctgtcggct gagccagcac tgtatgcacc gtatagccag cacgcacagc agcctgcttt
    14401 gatttttctc caaaacaaat aatacgtgta taactgctga tcatttctgg agactctccg
    14461 cacgcttgta aaccagcagt aactgtttcg acagaacggg cgttaggaaa aatgattgta
    14521 tccattcgct cttcgtcacg gaggcgtctg aaggtttgtt ccgtttgagg tacacggtca
    14581 tatgcatggg taacaataaa atcttgctcc tcagcgaaag atagaagttc ttcttttcca
    14641 atccaacctg catcacccag gatcaccagc cgggatgcat tcgaatctcg ttctgaaatt
    14701 tgtcttgcca gacaatgata cgattctaaa gcctttactg tttttttaga cagaccatag
    14761 aattctccct gaatgctccg aatatccatg ttatttgcct gtaaagacgc aaagaaaact
    14821 tctacacttg ccggggaaag aaagagcaaa tcatgatgaa ccgggatatc cgcttctctc
    14881 agcagttgct tttttatttg catccgcgga aactcaaaga cttctgcccc tttgtctctt
    14941 aaacgcgcac cgatttcact catttcttca ctcgaccgtc ctagcagcag atgctgacta
    15001 aacaacggct tgctttcaaa ccagctttct ccctctttta atttgcttac ctcgcccact
    15061 aaaataatgg caggattttt aaaatggtct gcctttgctt gctctacaat ggttccaagg
    15121 cttcctagca gggttctctg ctttcccgtc gtcccccact gaatgagtaa gaccggggtt
    15181 tcggatgatc ggccatgtga ggtcagttgt tctgcaatat aaggcagatt cccgattccc
    15241 atataaaacg caatcgtatc aattccattt gccaaggctt tccaatcaat caacggctcg
    15301 cctgctggag acttgtcatg gcctgtgatc acagcaaagg agagactatg ttcacgatgt
    15361 gtaactggca cgcctgcata ggcagcagct ccgattcctg ctgttattcc cggaacaatt
    15421 tcatagggaa cacctgcatt ttttagtgct tctgcttcct cgccaaccct gccaaataca
    15481 cttggatcgc cgccttttaa acgcactaca ttcttacctt ctaagccatg ctgcactaat
    15541 aacgcattaa tcgcttcttg acgcaggata tgcttctttg gcatctttcc gcaataaatc
    15601 atttccgcct gaggtgaggc atgttccagt aagagagggt taaccagcct gtcgtataaa
    15661 acgacatcag catgctttaa atacgtatag ccttttaatg ttaataaccc aatatctcca
    15721 ggacccgctc cgataagata aacacatccc tgttttttca ttgtttattt caccctcttt
    15781 tcgctttcct tgtttcgtgt tctatcaaat agaacctatt ttccagctgg agacatcgac
    15841 tttagaataa aaagaagagc agggcggcaa atccagtcct gcccctctgt ctcaaggtaa
    15901 ctatttcaaa caattaatcg tgaaagtcta atcccgaggt aacagctttc acatatcctg
    15961 tacggataac aaaatcaccg aagtgctccc cgtctaagcg ttccttcgca tagtgacgta
    16021 taatcggctg caacgtttct aaaatttctt tttccccaat attctcgcga tagagcttat
    16081 ttaagcgttg accagaaaaa cctgcaccca agtacatgtt atacttgcca ggcgcttttc
    16141 caataaagcc gatctcgctt aacgccggtc gggaacagcc atttggacaa cctgacattc
    16201 gaatgacaat ttcttcatca cggagtcctt cttcttccag catggtttca attttttcta
    16261 ataatgcagg caaataacgt tctgattcag ccatcgctag cccacaggtc ggaaaagcta
    16321 cacaagccat ggaatttctc cgcaatgcag attgctcttt cccatctgcc aaaccatatt
    16381 gcgctacaag ctcggcaatt tcctctttct tctcgctgga gacatttccg ataatcaagt
    16441 tttgattcgg tgtcaaacgg aaatctccgg tatgaatttt ggcaatttca cgcaaccccg
    16501 tcatcaattg ataatcatct ttatcttgaa ttcgcccatt ctgaataaaa agggttaaat
    16561 gccaatggtt cttggttccc tttacccagc catagcgatc accggtatga tcaaaatgga
    16621 aatcacgggc ttcttccagc tgccatccca gacgttcggt aagttcactc ttgagccagt
    16681 caagtccgcg cgcatcaatt gtatatttga agcgtgcatt ctttcgcaca gaacgatttc
    16741 cataatcacg ttggatagta ataatttttt cggcaacatc cgtaatttgc tccggtctgc
    16801 agaagccgat gattcttccg agctgcggat aagtgttggt gtctccatgt gtcatgccca
    16861 tgcctccgcc tactgccaca ttaaatcctt gcaatcgtcc atcctccagt atcgcaatga
    16921 aacctagatc ctgtgaaaag acatctatat cattggatgg cggcaccgca agcccaatct
    16981 taaactttct tggtaaataa accggcccat acatcggttc cacttcttca ttttctttgg
    17041 agtcaacaac cttctcccca tcaagccaaa tctcatggta cgcattcgtg cgcggtgaca
    17101 aataatcgct caaaaccttc gaccattcat aaacctccgc atggacctcg gactgatccg
    17161 gattcgggtt acacatcaca tttctgttca catccccgca agcagcaagg gtatccatca
    17221 aagcttcatt aatacgcttt atactttttt tcatattcca tttcaggatt ccatgcattt
    17281 gaaacgcctg tcttgtcgtc aatttgatag tatgattccc atattccctc gccaattcat
    17341 caataaccag ccattgttcc ggggtcgcta ctcctcccgg tactcggaca cgtaccataa
    17401 attgataggc aggctccagt ttctggcgct gccgttctgt ccgtaaatcg cgatcatcct
    17461 gcaaataact tccatgaaat ttcattaagc gattatcgtc gtctggaata ccagcgctta
    17521 accggtcctc caatgtttcc gataatgttc cccgtaaata attgctttct cttttaatcc
    17581 gttccacatc acttggtggt ccatcttgtg ttggaatgac tttatcgttg gtcatttctt
    17641 gttctccctc cccttttagt aaacatctcg ctgataacgt ttctcttgca gcatattatc
    17701 taaataagtt tgggcctcat cggtagtgag attcccttcc ttttcaataa tggtcactaa
    17761 cgtatcatga acatcactcg ccatgtgctt ctcatcaccg catacataga ccgttgctcc
    17821 atcttccagc cactcgtaaa gctccctgct ttgctccagc atgcggtgct gaacatatac
    17881 tttctctgca ttatcgcggg aaaaagcaac atccatcttt gttaatacac cgctctttaa
    17941 ccaacgttgc caatctgtct ggtaaagaaa atcagtgaca aaatgctggc ctccaaagaa
    18001 taaccatgat ttcccttctg cttccataac ttctcgctct tccacgaagg aacgaaatgg
    18061 tgcaattcct gttcctggac caatcataat aattggtgtg ctgggatcag ccggcagttt
    18121 aaagttcggg ttgttatgaa catagataga tagcgtttgc cccggctctt tcctatccgc
    18181 acattgtaca gaacacacac cgtttctttc tctgccgtat gtttcataac ggaccgcccc
    18241 aattgtcaaa tgaacttcct ctggatttgc ctttaaactg ctggctacag agtaaagtcg
    18301 cggcggcatt ttacgtaata aggtaataaa ttctttagct ggggcgccag caatcccata
    18361 atcgcgaatc aaatctaata aatcacgacc gtggatatac tcagttacgg ctgcttcgtt
    18421 ccccggctcc agcagatgtt gcagttctgg attctgtgta aatgcagcta ctttttgcag
    18481 taatggcttc gtcaagacgg taatttcaaa attcttttgg agcgcttcct gcaggagaac
    18541 ttcttccccc ttcttattaa taggaacaag ttcatttggt ttccatcccg cttctttgat
    18601 cagcgcatca accatctctg gatcattttc aggatagatt ccaatgctat cacctggttc
    18661 atattgaaga tttgatcctt ccaaggataa ctccatatga taagtttctt tatttgaacc
    18721 gcgtccattc agattaatat tttcatagat ttctgcctcg aatggattcg tacgtgaaaa
    18781 tgtcgatgat tctgctgctg cagagactat tgcatcaggt tgaacttgaa cggacacctg
    18841 cgattcagaa agtttgttta acacactttc aaaccattct gcagctggct catcataatc
    18901 taagtcacaa tctgtacgat ctgcaagtct cgttcctccc aactctgcta atcgctcatc
    18961 aaactttctg cctgtttcac agaattgttc ataggagcta tcccctaacg ccaagacgga
    19021 gtagttgagt ttttccagtt tcggagcacg gcggccgtga agaaattcgt aaaattgaat
    19081 cgcgttatcc ggcgggtctc cctctccctg cgtacttaca ataaccagta aattttcaat
    19141 gtttttgagt ttgtttggct taaagtcatt catcgaggca agtgtcactt tcattccctt
    19201 ttcctctaat tgttctgaca agcctgtcgc taagttttgg caatttcctg tctgcgagcc
    19261 aaagagaacc gtaacttcta caggagctgc ctctgcttca tttgcagact gtggaccagc
    19321 gagggccgca tccgttacct gtgcactttg gttcacattt tttactgcag acagatagcc
    19381 tcccagccaa atttgttgtg tttccgtcaa tgtcggaaaa agacgattga gcagatcaac
    19441 ctgctcttca ttaaatggac tatttttcac ttgaaattgc aacgttatct acctcacaaa
    19501 gttatttttt atcaattttt ttattgttag cgccttgaaa tttgaaatgc cgaataacct
    19561 atatatctgc ttccacaggc aaatgatttc tctcttttaa aaatgcgata attttatcaa
    19621 cacaggcgtc aatcgagagt tggtccgagt caacgaccaa ttctggacgt tccggctcct
    19681 cataaggaga actgattccg gtaaaattac tgatctcacc tgtacgcgcc tttttataga
    19741 gccctttcgg atcacggtct tcacaggctt ccaaagcgca ccggacataa atctcaacaa
    19801 attcattttc ctccaccaga gcacgcaccc tattccggtc ttctgcaaaa ggagaaataa
    19861 atgcggtaca aacaatgaaa ccagcatcga taaacagctt tgccacttct cctatccgcc
    19921 gaatattctc ttttcggtct tcttcgctaa aaccaagccc ttgatttaac ccgtgccgga
    19981 cattatcccc atcgagcaca taactattta aaccttgctc aaacagccgg tgctccaagg
    20041 cgtttgctaa tgttgacttc ccggctcctg aaagtccggt aaaccacaaa atacaacttc
    20101 catgcccgtt tcgctgctgc cggtcttttt tctgtactgc tgtatcatgc cacacgatat
    20161 gttctgcttc ctgtttcaaa tcagcaccca ccttttttat tcttatatgt ttactctgtt
    20221 ttaaatgtgt taaattcctc cgccttcgtc atacgtcgag cggcgttctg cgcgagttga
    20281 caaatataga ctatagaaac ctactgtcgc aatgaaaacg gacgtgatca caaagagtga
    20341 atagtaatca gcctgcttga atagaagaat gagtccataa gacatcacca gcgaaaaaac
    20401 aggggaaacg atccacacct tgataatttg cttgataatg ctctgctgcc acatatgaaa
    20461 ccctttctct gctgtgccaa tcccgacgat agcagaggtg gttatttgtg tcagcggcac
    20521 cggcaagcca aacacagatg ctgttattac cagactccct ccagttaagg aaaccgcact
    20581 tccttgcagc agggaaagct gcgtaatttt tttcccgttt gtttccatca cgcgtccgcc
    20641 cagcagtacc gctccaagtg atacaaagat tcccccgagc aagacagccg tggtcacatc
    20701 caacaatcca acgcctacta atggaccgac ggcattggca acattattca ttccagcggc
    20761 ataagcctcg atacagccgg cagcgataag taagaaagct agcggttttc tccactttcc
    20821 ggtaccagtc aagtctttcc agcgattttc tgcgtagcgt atccatttgc caaaaatcaa
    20881 accgataaaa aaagcgataa atggagtgat aagccagaag gaaacaatca caagcagcca
    20941 atcccagaac agagactggt aggccacacc tacaccgaca attgcaccca cgactacttc
    21001 actcgtagac aatggaatgc caagcatatt cgcaataaat aaagtcaagc aggcagcgcc
    21061 taatacaatg acaacaattt ctatatccag cacctcacca ggaacaattc cttgaccaat
    21121 tgtccgaacg acttcccctc cagataatgc gcctaacaac gcgaaaacac cgactagaat
    21181 catggcaaca cgttttttag gaattgcgcc gcttccatag gctggcccca tagaggcaac
    21241 tgtcccactg gctccgatgt tcattgcaaa gaataaagca attataaagg caacagctat
    21301 cagcatgatg ccacacctct ctccctcttc cctaggctac gcactacgca ttcacttttt
    21361 tcttcattcc ccggataagc acctcaacaa cttctttccg actgaattca ggaggaggag
    21421 taattccatt gcttaacatc tcccgtactt ttgttccgga caaaatgaca tgatcttctt
    21481 tatcatgcgg gcatgttttc gtggatgcca tatttccaca tgctttgcaa taaaaactat
    21541 gctcaaaaaa gagcggtctg atgccaagtt ctgcttccgt aaaatttcga aaaatcaatt
    21601 gagcgtcata agttccataa taatccccaa cccctgcatg atcacgcccg acaatgaaat
    21661 gggtacatcc ataattttta cgcactagtg catgaaatat ggcttctctt ggtccggcat
    21721 atcgcattgc agctggaaat acagcgagaa atacccgatc atgcggataa tattttgcta
    21781 agagagcttc ataactctcc attcttacgt tagctgggat atcgtctgct ttggtttctc
    21841 cgacgagggg gtttaagaac aacccatcaa caatttctaa cgctgccttc tgaatatatt
    21901 catgtgcacg atgaacagga ttccttgttt gaaagccaac gacttgcttc cagcccagct
    21961 tgtcaaactg tgctcttgtt tcctttggat caaggtagta cgtttcaaaa cggtcgcgct
    22021 ttacccgttt tattaaagtg attggtccag ctacatagta atccgggcgc gcaaacagct
    22081 tctttactcc tggatgatta ttatctgctg tttgatatac ctgttctgct tctgccagtt
    22141 tattcggttc atatacttcc ttgacgtcta tcacgccata aacttcattg ttgtagataa
    22201 gctttgctgg ttttccaatt tccagcgcat ctgcagcctc ttctgttaca ggtaaagtga
    22261 ttgggatact ccaggccgtg ccatcagcta aacgcatatt tcttacgact gtc
//
