LOCUS       NZ_BOQQ01000001        24508 bp    DNA     linear   CON 16-SEP-2024
DEFINITION  Shouchella clausii strain J1TS1 sequence01, whole genome shotgun
            sequence.
ACCESSION   NZ_BOQQ01000001
VERSION     NZ_BOQQ01000001.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Shouchella clausii
  ORGANISM  Shouchella clausii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Shouchella.
REFERENCE   1
  AUTHORS   Okamoto,M., Kumagai,M., Kanamori,H. and Takamatsu,D.
  TITLE     Antimicrobial resistance genes in bacteria isolated from Japanese
            honey, and their potential for conferring macrolide and lincosamide
            resistance in the American foulbrood pathogen Paenibacillus larvae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 597181)
  AUTHORS   Okamoto,M., Kumagai,M., Kanamori,H. and Takamatsu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2021) Contact:Daisuke Takamatsu National
            Agriculture and Food Research Organization; 2-1-2 Kannondai,
            Tsukuba, Ibaraki 305-8602, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.2
            Genome Coverage                   :: 1380x
            Sequencing Technology             :: Illumina NovaSeq 6000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018332735.1-RS_2024_09_16
            Annotation Date                   :: 09/16/2024 05:58:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,326
            CDSs (total)                      :: 4,235
            Genes (coding)                    :: 4,197
            CDSs (with protein)               :: 4,197
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 5, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 5, 3 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 14 of 38
            Pseudo Genes (incomplete)         :: 28 of 38
            Pseudo Genes (internal stop)      :: 6 of 38
            Pseudo Genes (multiple problems)  :: 9 of 38
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:04:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 121450
            Orig. end                         :: 145958
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BOQQ01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24508
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24508
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24508
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14508](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14508
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            46..1179
                     /locus_tag="KI354_RS00490"
                     /old_locus_tag="J1TS1_01060"
     CDS             46..1179
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008296483.1"
                     /locus_tag="KI354_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01060"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_212929666.1"
                     /transl_table=11
                     /translation="MNIIGKTAMLHLLETLVNIDSGSYYKTGVDTVGEVLIRAYEPLGF
                     KATVYKQPTYGNHVLLQHAEAKQPTILLLAHMDTVYPVGTIKKQPFSIKGERAYGPGVI
                     DMKGSHVTAFAAIKALHGANPDAAKNVALLLTSDEEIGAPTGRSLIEEHGTGKRAVLVM
                     EPARKDGSLVTARRGGGRFTLDVSGKAAHAGVEPEKGRSAIAELAAKIIKLDALSDHDA
                     GISINTGLIEGGTSVNTVASHAKAQIDVRISKLNQAEPLEQHICAICQQPWLDGTTITV
                     TGGLTRPPMERNGDTIELFSLIKALGTSMGLHVIETATGGSSDASFTSALGIPTIDGMG
                     PVGGNQHSEAEYLEIESLEERALLLAYTIEALSAKTK"
     gene            complement(1239..1656)
                     /locus_tag="KI354_RS00495"
                     /old_locus_tag="J1TS1_01070"
                     /pseudo=""
     CDS             complement(1239..1656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017674182.1"
                     /locus_tag="KI354_RS00495"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01070"
                     /product="ferritin-like domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYDNALYEYRPQHDSIVSDLTKAINGEYSAIHCYERLAQLAPTDE
                     QRHRILEIRQDEINHFHRFSQLYTQLTNRQPTPQITEECPAHYRDGLTFAFNDEQNTVD
                     FYLKAADRASQPLVQEAFRRAAARCLVSLFFDENV"
     misc_feature    complement(1957..1973)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            2032..3915
                     /locus_tag="KI354_RS00500"
                     /old_locus_tag="J1TS1_01080"
     CDS             2032..3915
                     /EC_number="2.7.1.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /GO_process="GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01995.1"
                     /locus_tag="KI354_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01080"
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="WP_212929667.1"
                     /transl_table=11
                     /translation="MDYKKLGRDVLELVGGKENVAMLTHCATRLRFEFRDPSKVKASQI
                     EQLPGVISVVDKGGQFQVIVGNEVQQAFREIQKQIGTVAPGKGSGQGPRKEKKGWVSRF
                     ISVISTTFTPMIPAIIGAGMIKAILAVLVLTGVLTDQSQTFFVLNTIADAAFFFMPVLL
                     AYGASIKFETSPIMSMTLAGVLLHPNWATVLASEEALHFIGVPVRLTDYAGSVLPIIIT
                     VWIMSYIERFAERVSPSMIKFFMKPMLILLVTAPLALVVIGPVGTYLNDLVALGAESIN
                     THASWLIPMLMGMLQPFLIITGTAWAMTPIATDQLSRNGEEMINGPGMLASNIAQGAAT
                     LAVAAKTKNKQLKQLAGSAGFTALIGITEPSLYGVTLKLKKPLIAAMIGGGCAGIYAGL
                     SGLVRYAFVSPGLAAVPAFIGSNPMNIIHALITILIAFAVAFAVTWILGFEEPTDKEAN
                     NREHTKQTNSDGQQEAVSIGGTVASPLSGQLQPLSEVNDDVFSSGLLGKGVAVIPDRNE
                     ARAPFSGEVVTFLDSKHAIGLKGDNGIELLIHIGIDTVQLQGEYFEAHVKQGDRVEQGD
                     LLVTFDKKAIVDKGYEVVTPIIVTNHDQFATVKPVEAGYIEHGQPIITVSN"
     gene            3929..5356
                     /locus_tag="KI354_RS00505"
                     /old_locus_tag="J1TS1_01090"
     CDS             3929..5356
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018393100.1"
                     /locus_tag="KI354_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01090"
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_212929668.1"
                     /transl_table=11
                     /translation="MLYKQLKPFPQKFLWGASTSAYQVEGAADTDGKGKSVIDMMDHPE
                     GTAGFTVASDHYHRYKEDIRLFHELGLKAYRFSIAWTRIFPEGTGTINEKGLAHYEQVI
                     DELLHYGIEPIVTLYHFDLPYALEEQGGWNNRKTIDAFVEYTKVLFARLGGKVNYWLTI
                     NEQNTLILHPGAVGIPKGGKLPSKKELYQQNHHMLIAQGKAMALCHQMCPHAKIGPALN
                     MTSMYQATSKPEDALAAHNWETIRGWSFLDLAVHGRYNHLLWSYLEERDWLPDVEEGDL
                     ALIKMGQPDFIAINYYSTATIAESAGSASDVSPRAGDQQIMLGEPGVYRAEDNPYVDKT
                     KYGWVIDPVGLRLTLRKVYERYHLPILITENGIGAPDTLEEDGTVHDDYRIAFIRAHLE
                     QVQWALTDGVDVFGYCPWAAMDVVSTHQGYGKRYGFIYVNRGEFDLLNLKRIKKDSFFW
                     YKRVIESNGTDGLFETE"
     gene            5384..6223
                     /locus_tag="KI354_RS00510"
                     /old_locus_tag="J1TS1_01100"
     CDS             5384..6223
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013070.5"
                     /locus_tag="KI354_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01100"
                     /product="PRD domain-containing protein"
                     /protein_id="WP_095254354.1"
                     /transl_table=11
                     /translation="MKVEKILNNSLVLSKDEAGHEVIVMGKGIGFNSKQGDTIAQAAIE
                     KIFVPNDQRTKQEYVRILENVPKEHLEGIHAALEQLKGRWQKEIDDRVFLMLLDHIAFA
                     IERTQKGITLQNKLLHEVRTHYPEEFEAGLSVVDDLNERLAIHLPEEEAGNIAFHLVNA
                     QTEDKNMGNTVLSMKMLKDMLNLVQYQLNIRFDSRSMRYTRFVTHLQYFIHRILENKQL
                     HTKEVFLYEQFKAKYPHEHKCAKAIASYGENMSGHAVTDEELLYLLIHLARLTNSEE"
     gene            complement(6446..6670)
                     /locus_tag="KI354_RS00515"
                     /old_locus_tag="J1TS1_01110"
     CDS             complement(6446..6670)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI354_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J1TS1_01110"
                     /product="hypothetical protein"
                     /protein_id="WP_095254353.1"
                     /transl_table=11
                     /translation="MIAIILFCLNVILYYVSTLFQFEPTYTIGLWTFLSIVGVLFAFKA
                     AKPSVKIIGLILNGAFLLFSLLLIIALFL"
     gene            complement(6710..8494)
                     /locus_tag="KI354_RS00520"
                     /old_locus_tag="J1TS1_01120"
     CDS             complement(6710..8494)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011248399.1"
                     /locus_tag="KI354_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01120"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_095254352.1"
                     /transl_table=11
                     /translation="MGSTTERPIQLKEFISLMRLYRPSLWLLGLALFLVLMETALSLAV
                     PLLTMNLVDITVESNFSGTTAALIAGVFIVQIILSGISMYMMIYIGQIMVAKLRKDLWH
                     KVLRLPVSFYDQNSSGETMSRITHDTNVIKNFFTDQLIPFLSGTIKIIGSIIILFALNW
                     SITLLLLLIVPVSLAVLKPLGRKTYKVSKALQDETASFQGDLGRVLSDIRLVKSSIAED
                     PETSQGNNRIDQLLKHGLDTGKIMAIISPLMTTITLLVLVVVFGYGGIQVANGTLSAGT
                     LVAIVFYMFQIIPPISQMGHFFTQLQKAKGATERITYIMEENLESQLAASVSYPHNQET
                     VARVNGIRFSNVSFSYPNGSQILKNVSFSANASEVTAIVGPSGAGKTTLFSLIERFYPP
                     SEGTIEYDNQPINDFDVQEWRQKIAYVAQDSPLMAGTIRYNLTYGHAEKSSDADIHAAL
                     EKANLTSFITSLPDGLETEVGERGILVSGGQRQRLAIARAILRNPQILLLDEATAHLDS
                     HSEFLVQEALNQLMLSRTTLVIAHRLSTVQHADKLVVVQSGEITGEGTHDELIEHHQFY
                     RELVDRQLYKKESPELIN"
     gene            complement(8478..9389)
                     /locus_tag="KI354_RS00525"
                     /old_locus_tag="J1TS1_01130"
     CDS             complement(8478..9389)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF037898.5"
                     /locus_tag="KI354_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01130"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_011248398.1"
                     /transl_table=11
                     /translation="MDNRIGMEIRNLRMKLGMSQENISSSVVSQSAISKIENGKYIPNI
                     IVLEAIASKLGVPVDHFLTLSTSYNGEYIETTYEMIEQLSLHEEYEELNRLTAQLIDCG
                     QAVEFPNWFKDYIRIHHLFSEYQCRKKDAQTTWMKLKCMAGCLPFEQSIQTKFHLYLGI
                     IHSHMKTYSYSETLDYLQKSLASVEGIKGKNTYLHKKNLKIYILYQKTIIELNYHHYDA
                     ALKDIGQGLQLSRNYACTAYVGQFLYYKGLCLEKKGVPFKNILKHYEEAHFFASFTNNL
                     PFKKLLSDKLSARKEESYGVYN"
     misc_feature    complement(9544..9553)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    complement(9595..9604)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(9613..9627)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            9737..9871
                     /locus_tag="KI354_RS00530"
                     /old_locus_tag="J1TS1_01140"
     CDS             9737..9871
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="KI354_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01140"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_073304601.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.3e-18, bitscore:
                     59.7, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 3.4e-10, bitscore:
                     34.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKAFDLDLEVVHTKAKDVQPDFTSVSFCTPGCGETGSFNSFCC"
     CDS_motif       9737..9802
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEKAFDLDLEVVHTKAKDVQPD"
                     /locus_tag="KI354_RS00530_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9803..9871
                     /prepeptide="core"
                     /locus_tag="KI354_RS00530_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="8.10"
                     /molecular_weight="2109.4"
                     /monoisotopic_mass="2107.9"
                     /core_sequence="FTSVSFCTPGCGETGSFNSFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKAFDLDLEVVHTKAKDVQPD"
                     /leader_location="[9736:9802](+)"
                     /alternative_weights="2127.4"
                     /alternative_weights="2145.4"
                     /alternative_weights="2163.4"
     gene            10001..13150
                     /locus_tag="KI354_RS00535"
                     /old_locus_tag="J1TS1_01150"
     CDS             10001..13150
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="KI354_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01150"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_011248397.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.2e-189,
                     bitscore: 625.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.6e-15,
                     bitscore: 52.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.8e-37, bitscore:
                     124.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSEQLLYEPVDTIMLRAPILSLSHDHQNASKDDIIPILKEYIE
                     RPEIKEALAVASPNLFQSLDKIHGDPRSKKTRNAVSSLLKFLIRMSSRPTPFGLFSGIA
                     IGELGNKTVGSLLDTKQHQKRARPDMEWLLGVVSKIEKNQTIAKKLNVVFNDAVYQTDD
                     RVYLHYFSNCGQLRSSENQERKDNISIRKTVVVEFVQSVAKKPISISELINQLQLTYTS
                     ASINEIESFVWNLFQQEFLISELRPPIVNCAPLSYVIQILESIPEATEIGAMLKGIEAD
                     IETYNQLPIGQGLDFFQTLTAKMQDIHPSKQPLQVDLRLTCAEKVRINRSIGEQVANAA
                     EWLWRLSKNETGVAHLREYHVEFLEKYGVNREIPLLDLLSDEKGLGAPPTYKYPPSAKS
                     VNPPQMKSTHRLLMEKYIQCLRENAKEITLTESDLQKLMDNDTDDVFAPNSGELFVEVL
                     ASSAEEVDKGNYQLAIGTNVGSQELGQTFGRFSDMIASEENRNLMEEQKKIEETCTDVE
                     TEYVELSFLPQSGRASNVSITHSTRNLHTTIATNANGQNKKLLLEDILVGATLGRFYLK
                     SKKSNKRLVFTSNNMFNYESAPNCFRFLREVSLEDGKAIQGVNLGSLREFTFIPRITSG
                     KVILSPAIWKLNDQIEELSDFSMPLEEWIEQFSTWMKKMQVPEQVFMAYGDNRLYIHLK
                     NANHMQELRSELRRRGRVQLQEIIGGYREKQWVKSPLGRHNAEFIVPFKKRPHVPAKPT
                     VMIKPVAEVPIECREKEPGTDWLYFKLYGPIHKQQKLISTQIPTLVAELENHKLINSWF
                     FIRYYDSEPHLRLRFHGDPKTLLAGALPVFQKWYAAQRLAGNVKKVVIEPYEREIERYG
                     GLSLMPLMERYFEKDSLLTSNLLGLSSKQALKEPLELIASMYVVYFLTEYGWHHERQLE
                     WISKWSEDPAYSKEFRPYRNDVLKWLDQEENWKALKEQKGFLFKLFSKNEAIIHELSHN
                     MEITPMTNTEERVVGSLIHMHCNRLLGTDRDREKKAMAFVRQIIESQKHWNKTKGRPLN
                     V"
     aSDomain        10457..10744
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KI354_RS00535_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="7.60E-17"
                     /identifier="RREFam001.1"
                     /label="KI354_RS00535"
                     /locus_tag="KI354_RS00535"
                     /protein_end="248"
                     /protein_start="152"
                     /score="52.8"
                     /tool="antismash"
                     /translation="VFNDAVYQTDDRVYLHYFSNCGQLRSSENQERKDNISIRKTVVVE
                     FVQSVAKKPISISELINQLQLTYTSASINEIESFVWNLFQQEFLISELRPP"
     gene            13162..14508
                     /locus_tag="KI354_RS00540"
                     /old_locus_tag="J1TS1_01160"
     CDS             13162..14508
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="KI354_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01160"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_095293931.1"
                     /sec_met_domain="LANC_like (E-value: 2.8e-85, bitscore:
                     281.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKVVDDQEKQETKRIIARLTEKLNDPQKVEEIVMDKNNVTTIS
                     KVNPWDPVSLSHGFAGTILFFSELHKMYPEEKWDHVAHNHIVYASNYLKNGVHSISLFG
                     GITGFAFSVFNASENGTRYQNLLAKLDEVIRRVAENEIEEEKQRNGLGALPTFYDVIQG
                     YSGIGRYLLERRKDTPAFNGLIEAILRQFVEMTATITWEEHEVPGWYVTQENQFLEKDK
                     KIYPFGNFNLGLAHGIPGPLSFLSLCLLKGIEIPGQRQAITTIGNWLVRHAKSNSTGAP
                     VWAHRVGVKEAIANKYTVIDEREGWCYGNPGVARSLYLAGKALNDLPYQEMAVKCFHGI
                     KEKTLEELDLQSATFCHGKSGLLQIMVRMKNDLNINDFDKLINQLENGIKEQYRDQHPL
                     GFKDFEIGSRTNELDKAGLLEGAAGVGLALLSRTGDDSELFWDKAFLIS"
     gene            14519..15091
                     /locus_tag="KI354_RS00545"
                     /old_locus_tag="J1TS1_01170"
     CDS             14519..15091
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729076.1"
                     /locus_tag="KI354_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01170"
                     /product="flavoprotein"
                     /protein_id="WP_095293932.1"
                     /sec_met_domain="Flavoprotein (E-value: 3.1e-30, bitscore:
                     99.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEKEEKNILVGISGSISVINMPSYLAFFKHTYGHVKVIITEQAN
                     KLFPASSLSLFCDDIFQDHNETIDPNTASHVGLARWADLFIVLPATANKIGQVANGLGM
                     DLLSSTILASTKPVLFCPNMNEAMWNNFFVKRNIALIKEGGHIIIPPVEKEAYEVASGS
                     IRKNFIIPDMYTIAQEIDKAMAVEENS"
     gene            15202..15924
                     /locus_tag="KI354_RS00550"
                     /old_locus_tag="J1TS1_01180"
     CDS             15202..15924
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011248394.1"
                     /locus_tag="KI354_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01180"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_212929669.1"
                     /transl_table=11
                     /translation="MEKIIETKNLTKKIKGKPLVEEINLSIAKGEICGLIGPNGAGKTT
                     IMKLLTGLLIPTSGEVKLNQWNVHKQRKEAMRSVGAIIESPIFFEFMTGRGMLLNLARL
                     HGLNKQERQDKVAEALTIVGLDGRGDEKIRTYSLGMKQRLGIAQALLGNPEIVILDEPA
                     NGLDPMGMRELRELILQLNKEKNITFLISSHLLDELQKICSTLVIIKQGNVLFYGKQEE
                     IYDKAENNLEDIFIGMMT"
     gene            15924..16331
                     /locus_tag="KI354_RS00555"
     CDS             15924..16331
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="KI354_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_095293934.1"
                     /transl_table=11
                     /translation="MGQLIISEFERLWSRWSIRLLVMTLPLLVIVTGVYFQNHNRNRSM
                     DAVDYATSLNFPILSLSEHLFITFNILLIFICAYVITEEYQQKQIKLIVLRAYSMSQIF
                     LSKFIVMATSLFICFFLSLLLGLLLRWADHV"
     gene            16333..16752
                     /locus_tag="KI354_RS00560"
                     /old_locus_tag="J1TS1_01190"
     CDS             16333..16752
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI354_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J1TS1_01190"
                     /product="hypothetical protein"
                     /protein_id="WP_212929670.1"
                     /transl_table=11
                     /translation="MPERSILFVSEADVTNTEMVLYGLNYYGIAFLTSLAVLSLFCFIA
                     IIMPSVNALLGSGICILFFSIVGPQLLEQSTAFAEGSNISYVVYASITKIQYTGISLLL
                     SGGELSGWLIAVTSFYLLVFLGGAYLVFTRRNYYV"
     gene            16765..17532
                     /locus_tag="KI354_RS00565"
                     /old_locus_tag="J1TS1_01200"
     CDS             16765..17532
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI354_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J1TS1_01200"
                     /product="hypothetical protein"
                     /protein_id="WP_095293938.1"
                     /transl_table=11
                     /translation="MKHLIISELERLWKMRMMKILLLLLVGISFFSAYFLTWFDLGLYT
                     ADSETPLNAVNFPWFLLREVSFFVTLVIMPLFCVVVLNSPIKAKTYNLVLYRPFHRLEF
                     LLSKWGTLLLIAVFITVFIWLIGVMLGFFFYQVPEYVTFYGDLTRYSILNGYIYSAKLY
                     FLFWAVIAAGIAIASVMSIMAPNPIIAYFLLMIAYVVPIYFSNELTFFLMPTQSIFISL
                     SETNMPLLYMALPLIVLFGGGISSLLWVKQDFK"
     gene            17553..18227
                     /locus_tag="KI354_RS00570"
                     /old_locus_tag="J1TS1_01210"
     CDS             17553..18227
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="KI354_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01210"
                     /product="response regulator transcription factor"
                     /protein_id="WP_011248391.1"
                     /transl_table=11
                     /translation="MEHILIVDDEIQITSIVGELLQEEGYQTTVANDGMNAIKLIKEQD
                     FDLIILDIMMPYVNGLDVCRSVREFTDVPILFVTARTSMNDQINGLNIGGDDYINKPFT
                     HEQLLARIKTHLRREKRKQQPTDELVYGKIKLDRRTNELRYGETPLLLTNKEFKIMEML
                     MSNPRQIFSKDHLYETIWGVEATGQSHTVTEHIRNIRIRIHKIDPMANLIHTVWGVGYK
                     LE"
     gene            18220..19644
                     /locus_tag="KI354_RS00575"
                     /old_locus_tag="J1TS1_01220"
     CDS             18220..19644
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="KI354_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01220"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_095293940.1"
                     /transl_table=11
                     /translation="MNKKRTSIKQQIRLTIAKTILLSFFATIIVVLASWAIVMSIDDRY
                     YANYYESQVPQITDQVQSLNRELVNSQASGAKQLEEIIPTPGMEYQVLDEQGTFLYGSF
                     SANVNPEGVHLLNKVNKSFLEENTATSFIPIVDQNGTFAGSVVLQYKLESEVEALFNIF
                     FVCLFLTPFFFIMIFTYYYASKLGKNYYARIQKLIVATELVRKQNLDFEIEADGNDEIT
                     KLSTSFNIMKQALQDALYQQWNLEKNRSEFISSVSHDLKTPLTIMKANAQMLERKIKDE
                     QHKTYIANMIGEIERTENLVQELGTKMNDEESFFAIETKTVEPGHFFKTEFAKYKDFVQ
                     NEGLEFHTSVLDYRKTANTIQIDVQKITQVIDNLISNSLRFAEPYDGHIDCHAECHDDY
                     VKVTVSDNGKGFTESDLHYVFQKFYQNNDSADPHKGLGLYIVKHIIEKHGGNVQAWNDK
                     GAVVSFQLPAVPKNSH"
     gene            complement(19679..20521)
                     /locus_tag="KI354_RS00580"
                     /old_locus_tag="J1TS1_01230"
     CDS             complement(19679..20521)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024245.5"
                     /locus_tag="KI354_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01230"
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_212929671.1"
                     /transl_table=11
                     /translation="MNTLFFILAALSLFAFILGLIKPSLIRLPSRSRVCLYVIPVLIVT
                     SILHDSTQDPNKAQSAQLDRSQAKIETLEASLQDKETEMEELTVALEEAEESLKESEEQ
                     LELLQAEEGDVDGSFEEQLEEAKLEWEEEFREQIEEELEERITAEISEDYEDKLAALDD
                     KIKEKEQTIEEKETTISKLEEEVASASTNNGNETATTETETAQSSESASTNSCGPGTVK
                     INSASESKLQAIYEIGPDRAAQIIQLRPFSSYNDMKRIKGIGDARAEAIENQGIVCFD"
     misc_feature    complement(21062..21075)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.03"
                     /tool="antismash"
     gene            21162..22010
                     /locus_tag="KI354_RS00585"
                     /old_locus_tag="J1TS1_01240"
     CDS             21162..22010
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025625.5"
                     /locus_tag="KI354_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01240"
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="WP_095293945.1"
                     /transl_table=11
                     /translation="MQGTDRTVMMHFPNSQQASSLKIIQEPTSQIRSFYFKKSLLAQVE
                     ELEYANNYAIYFLFSDLENPSVYIGQSTQGIKRLRDHLREKDFWQYGILFVTDNNSFDK
                     LAIDFLEHQFIQLFKRSSFIVENHDLRNTKPTINWFAHATMNTFTNQITFLLEALGVSI
                     QEEEKENDRKLFPAEGEREASLYIHDGQFFLTKGSILHRPQERLKNWNDQGKLYYKLNA
                     RIDQLIDVKQAEVIDEGTVRLLQDVVCSSPSAAADLCSGTSKNGWTFWRGLEEEGKNFG
                     R"
     gene            22058..22609
                     /locus_tag="KI354_RS00590"
                     /old_locus_tag="J1TS1_01250"
     CDS             22058..22609
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI354_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J1TS1_01250"
                     /product="hypothetical protein"
                     /protein_id="WP_051881178.1"
                     /transl_table=11
                     /translation="MKLTKHDFYFGSLLSLLVKSGFAPAIIDGGELSRIYSLSLDQGDI
                     KVYAKYSSKPCNEKKEEQRWDYHFSKEEVNKIEGLIKDNSLIFALICGQERLKNSEITF
                     LDIDQLKECLGSAYRESNRRVSIKVDKRGRSFYAYGSGLDGVEKPIKIKRNAKERLKEF
                     FPNLDNFQIKEQLSQKRIEV"
     misc_feature    complement(22089..22104)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            complement(22733..22939)
                     /locus_tag="KI354_RS00595"
                     /old_locus_tag="J1TS1_01260"
     CDS             complement(22733..22939)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475609.1"
                     /locus_tag="KI354_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01260"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_035203419.1"
                     /transl_table=11
                     /translation="MRKVEIAINDLLHKHQLTIHALHLKTGIRRATLSEMASGKRERIQ
                     LEHIEKIADALDIDDMNEILRFK"
     misc_feature    complement(22980..22998)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.54"
                     /tool="antismash"
     gene            23041..23748
                     /locus_tag="KI354_RS00600"
     CDS             23041..23748
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012673.5"
                     /locus_tag="KI354_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_095293949.1"
                     /transl_table=11
                     /translation="MQSRQQLIPDLLTEAAYRMETTFKATSPNICTTITYNAQKSNIYA
                     LLQQRIHADYPTDILCFPHQDIPINSKHPIWLISLHPCQHELPQQPDVYVLSIALARSR
                     ELYCSYIYDVSRKKLYYAIKGGGAFLNEQRLRREEIMPLNEAVLRIKADYLHESNKRVP
                     ANKRVGVADQSTALEICRVAEGKTDLFMAMSESPHAFAAASLIAEEAGVRLMTVEGKPL
                     RWYKESSFWVGVI"
     gene            23828..24208
                     /locus_tag="KI354_RS21705"
                     /old_locus_tag="J1TS1_01290"
     CDS             23828..24208
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI354_RS21705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J1TS1_01290"
                     /product="Fic family protein"
                     /protein_id="WP_306203724.1"
                     /transl_table=11
                     /translation="MLHKVDHLKRELDARRPLPMATVQSLKKDFLVRNTYHSNAIEGNT
                     LTIFETKAILEDGIVVGGKSLREHLEVINHKEASLYIEEHLEEVVTERFIKEIHALVLS
                     GIDRQAAGAYRKRGSTDSWCDP"
     gene            24162..24419
                     /locus_tag="KI354_RS21710"
                     /old_locus_tag="J1TS1_01300"
     CDS             24162..24419
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014691.5"
                     /locus_tag="KI354_RS21710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J1TS1_01300"
                     /product="Fic family protein"
                     /protein_id="WP_306344750.1"
                     /transl_table=11
                     /translation="MPIEKEEVRIAGATHNVTSSHLIQDEMGQLVQWYNESNHLHPIER
                     ASRLHSKFVNIHPFRDGNGRTARLLLNFSLLSASYLPVFA"
ORIGIN
        1 tcgcttgcca ttttccatta ttgaaccggc caggaggtgc aacaaatgaa catcattggc
       61 aaaacggcca tgcttcactt gcttgaaacg ctcgtaaata tcgatagcgg ttcgtactat
      121 aaaacagggg ttgacactgt tggtgaagtg ttaatccgcg cttacgaacc gttagggttt
      181 aaggcaactg tgtacaaaca gccaacctac ggaaaccacg tactgttgca acatgcggaa
      241 gcaaagcaac cgaccatttt gcttttggca catatggaca ccgtctatcc tgtaggcacg
      301 attaaaaaac agccgttttc gatcaaagga gaacgggcgt atgggccagg ggtgattgac
      361 atgaaaggca gccacgtcac cgctttcgca gcgataaaag cattgcatgg cgccaacccc
      421 gatgcagcga aaaacgtcgc gctattgctg acaagcgacg aagaaatcgg cgctcccaca
      481 gggcggtcac ttattgaaga gcacggaacg ggaaagagag ccgtgctcgt tatggaacca
      541 gctagaaaag atggctccct tgtcaccgcg agacgaggtg gcgggcggtt tacattagac
      601 gtcagcggta aagcagctca tgctggtgtc gagccggaaa aaggccgcag cgcgattgcc
      661 gagctagccg ctaaaatcat aaagctcgac gccctctccg accacgacgc aggcatcagc
      721 atcaacacgg gccttattga aggcggcaca tcagtcaata ccgttgccag ccatgcaaaa
      781 gcgcaaatcg atgtccgcat ttcgaagctg aaccaagcag aaccgttgga gcagcacatt
      841 tgtgccattt gccaacaacc ttggcttgac ggcaccacga ttacagtaac aggcgggcta
      901 acacggccac caatggaacg gaatggcgac acgatcgaac tgttttccct tataaaagca
      961 cttggcacat caatgggctt acatgtaata gaaacagcaa caggcggaag ctccgacgct
     1021 tccttcacat cggcgcttgg cattccaact attgacggca tggggccagt cgggggcaac
     1081 caacatagcg aagcagaata tctagaaatc gagtcgcttg aagagcgtgc tctgttgttg
     1141 gcttatacaa tcgaagcgtt gtcagctaaa acgaaatagg aaaaccaact aaacgcaagc
     1201 gtcacagcga ttgagacgtt tgcgttttgc tatccgcttc acgttctcat caaaaaatag
     1261 agaaaccaga cagcgtgctg ctgctctgcg aaaagcctct tggacaagtg gctgagaagc
     1321 acgatcagct gctttcagat agaaatcaac tgtgttttgt tcatcgttaa acgcaaatgt
     1381 taacccatct cgatagtggg caggacattc ctccgttatc tgtggagttg gctgtctgtt
     1441 cgtcaactgc gtgtacagtt gggagaaacg atgaaaatgg ttgatttcgt cttgcctgat
     1501 ctcaaggatg cggtggcgct gctcatccgt aggcgccaac tgtgccaatc gctcatagca
     1561 atggatggca ctatattcgc cattaattgc tttcgtcaaa tcggaaacga tcgagtcgtg
     1621 ttgtggcctg tattcgtata acgcgttatc atacacggtg catccctcct tattgtaaaa
     1681 tgtatggaag aaatgcggat aggtgtctgt ctctatttgt tttttgtgct tgtttctggt
     1741 gtgtacgaac gttaggtttg taatgaatgg aacagcgtta tccttaattt tcggtcaagt
     1801 cttcccttga acaaacgttt ctgttcatcg aaaaaagaat attgcaatag gacaaaaggc
     1861 atgctacaat tcaaatgaaa tcggtttata agttaataac gattatattg gcgtgttact
     1921 ggtaatgcag gcaagaccaa aataagttgc tttttccgct tcggaaaagt gcatcttatt
     1981 ttggtctttt tttatggcat tttttgcatg ccgcgtaaag gagagagaaa aatggattat
     2041 aaaaaattag gtcgtgatgt gcttgaactt gtgggcggca aagagaatgt agcgatgctt
     2101 acgcactgtg cgacaaggct acggtttgaa tttcgcgacc cgtccaaagt taaggccagt
     2161 caaattgaac aattgccagg tgtgatttct gttgtagata agggcggcca atttcaggtc
     2221 attgtcggca atgaagtcca gcaggcattc cgggaaatac aaaaacaaat tggcacggta
     2281 gctccaggaa aagggagcgg ccaggggcca aggaaagaaa agaaaggctg ggtctctcgc
     2341 tttattagcg tgatctcgac gacatttaca ccaatgatcc ccgcgattat tggggcgggg
     2401 atgattaaag cgattttggc ggtattggtg ctgacgggtg ttttgacaga ccagagtcaa
     2461 acgttttttg tgctcaatac gattgctgat gcagcgttct tctttatgcc ggtgctgtta
     2521 gcgtatggcg cttccattaa gtttgaaaca agcccgatta tgtcgatgac gcttgctggt
     2581 gtattgcttc atcccaattg ggcaacggtg ttagcgtcgg aggaagcact ccattttatc
     2641 ggtgtgccgg tccgtttaac ggattatgcg ggttcggtgt tgccaatcat tattacggta
     2701 tggatcatgt cttatattga acggtttgcc gaaagggttt cgccgtcgat gattaaattt
     2761 tttatgaaac cgatgttgat cttattagtg actgctccgc tggcacttgt ggtcattggt
     2821 ccggtcggta cgtatttgaa tgacttggtc gcccttggcg ccgaatcaat caatactcat
     2881 gctagttggt tgatacccat gctcatgggg atgttacagc cgtttttaat cattaccgga
     2941 acggcgtggg cgatgacgcc gattgcgacg gatcaactgt cccgcaatgg cgaagaaatg
     3001 ataaatgggc caggaatgct tgcctccaac attgcccaag gagcggcgac actagcggta
     3061 gcagcgaaga cgaaaaacaa gcaattgaag caattggctg gttctgctgg gtttactgca
     3121 ttgattggta ttaccgaacc gtctttatac ggggtaacgc ttaaactaaa aaaaccattg
     3181 attgccgcaa tgatcggtgg tggctgtgct gggatttatg cgggcttgtc agggcttgtg
     3241 cgctatgcgt ttgtttcacc agggcttgcg gccgtaccgg cctttatcgg cagcaaccca
     3301 atgaacatta ttcacgcatt gatcacgatc ctaattgctt ttgcagtcgc gtttgcggtc
     3361 acatggatac tcggatttga agagcccact gataaagaag ccaacaaccg ggaacacaca
     3421 aagcaaacaa actcagacgg ccaacaagag gctgtttcaa taggcggcac tgtggcaagc
     3481 ccgctttctg gccagctgca gccgttatct gaagtcaatg atgatgtctt ttcaagtggt
     3541 ttgcttggca aaggcgtagc cgtgattcca gatcgtaatg aagcccgggc accgttttcc
     3601 ggtgaagtgg tgacattcct tgactccaaa cacgcgattg gcctaaaagg agacaatggc
     3661 atcgaattac tgatccacat tggcatcgac accgtccaat tgcaagggga gtatttcgaa
     3721 gctcatgtga aacaaggcga tcgcgtcgaa caaggcgatc tacttgttac gtttgacaag
     3781 aaagcaattg tagacaaagg ctatgaagtg gtaacgccga ttattgtcac caatcatgac
     3841 caatttgcaa cagtgaaacc ggttgaagca gggtacatcg agcacggtca accaattata
     3901 acggtaagca actaaggagg agtggcagat gttatacaaa caattaaaac catttccaca
     3961 aaagtttctc tggggggcgt ccacgtctgc gtaccaagtt gaaggcgctg cggatacaga
     4021 cgggaaagga aaatcggtta ttgatatgat ggaccaccca gaaggcaccg ccgggttcac
     4081 tgtggcaagc gaccattatc accgctacaa agaggatatt cgtttgtttc atgagctcgg
     4141 gttaaaagcc tatcgttttt cgattgcatg gacgcggatc tttcctgaag ggaccggtac
     4201 gataaacgag aaagggctgg cgcactatga gcaggtcatc gacgagcttc tgcactacgg
     4261 cattgagccg atcgtcacgt tataccattt tgacttgccg tatgcactgg aagaacaagg
     4321 gggatggaac aacagaaaaa caattgatgc ctttgtcgag tataccaagg tgctgtttgc
     4381 ccgccttggc ggaaaagtaa attactggct gactatcaat gagcaaaata cactcattct
     4441 tcatccagga gcagtcggca ttccaaaagg cgggaaactg ccgtcgaaga aagaattgta
     4501 ccaacaaaac caccatatgc tcatcgccca aggaaaagca atggcgcttt gccaccaaat
     4561 gtgccctcat gctaagattg gcccagccct taacatgacg tcgatgtacc aagcgacaag
     4621 caagccggaa gatgcacttg ccgcccataa ttgggaaacg atccgaggct ggagctttct
     4681 tgatttagcc gtacatggac gctacaatca tttgttatgg agctatttag aagaacggga
     4741 ttggctgcca gatgtcgagg aaggcgattt ggcccttatc aaaatggggc agccagattt
     4801 tatcgccatc aattattact ccacggccac tattgccgag agcgctggca gtgcaagtga
     4861 cgtcagccct agggccggcg atcagcaaat tatgctaggc gagccaggcg tctaccgcgc
     4921 cgaggataac ccgtatgtcg acaaaacgaa atacggctgg gtgattgatc ctgtcggttt
     4981 gcgcctgaca ttgaggaagg tatatgaacg ttaccattta ccgatcttaa ttacagagaa
     5041 tggcattggc gcccctgata cgttagagga agatggcacg gtccatgacg attaccgcat
     5101 tgcctttatc cgcgcccacc tggaacaagt ccaatgggca cttacagacg gagtagacgt
     5161 gttcggctat tgcccttggg ccgcaatgga cgttgtcagc acgcaccaag gctacggcaa
     5221 gcgctatggc tttatttatg tgaaccgcgg tgaattcgat ttgctcaatt taaaacggat
     5281 taaaaaagac agcttctttt ggtacaagcg cgtgattgaa tccaatggca cggacggcct
     5341 gttcgaaacc gaatgaaatg tcataaatga agtggtgaaa aacatgaagg ttgaaaaaat
     5401 attgaacaac agcctcgttt tatcaaaaga cgaagcaggg catgaagtca tcgtaatggg
     5461 aaaagggatt ggctttaata gcaagcaagg agacaccatt gcccaagcgg caattgaaaa
     5521 aatctttgta ccaaacgacc agcgcaccaa acaagaatac gtccgcattt tggaaaacgt
     5581 accaaaagag catttagaag ggatacacgc tgccctcgaa caactgaaag gccgctggca
     5641 gaaagagatt gacgacaggg tgtttcttat gttgctcgat catattgctt ttgcgattga
     5701 acggacacaa aaaggaatca cgttgcaaaa caaactgctg catgaagtcc gcacccacta
     5761 tcccgaggaa ttcgaggccg gcttgtccgt agtcgacgac ttaaatgagc gcttggcgat
     5821 ccatttgcct gaagaagaag caggaaacat cgcctttcat ctggttaatg cccaaaccga
     5881 agacaaaaac atggggaaca ccgtcttgtc gatgaagatg ctgaaggaca tgttgaatct
     5941 agttcagtac cagctcaaca tccgcttcga ttctcggtcg atgcgctaca cgagatttgt
     6001 gacccatctt caatacttca ttcaccgcat cttggaaaac aaacagcttc acacaaaaga
     6061 ggtgtttttg tacgaacagt ttaaagccaa gtacccacac gaacataaat gtgcaaaggc
     6121 gatcgcaagc tatggggaaa atatgagcgg ccatgccgtt acagacgagg aattgcttta
     6181 tttgctaatc catttggcgc ggttaacgaa ttcggaagaa tagataaaac gaaactttat
     6241 tggctacttt cctcattcgt ttggattttg tcatcgaaat atgtgccgtc tacccagtgt
     6301 tggaacctaa aaatcaagta ctgctatctt cactgttcgt ccccattgtg gcacagctgc
     6361 tgttcacaat ggggacggca catagctgta tttaatcaga taaactagtt tatcctctat
     6421 atgcacgaag cctcgagtct tatatttaaa gaaacaaagc aataatcaac aagagagaga
     6481 aaagcagaaa ggcgccattt aaaatgagcc caatgatttt gacagatggt ttggcggctt
     6541 taaacgcgaa caagactcca acaatagaga ggaacgtcca taagccaatc gtatatgtcg
     6601 gttcaaattg aaaaagagtg ctcacataat ataaaataac gtttaaacaa aacaggataa
     6661 tggctatcat caatcttcac tactttcctt taaaagtcta cgtgctcttt tagttgatca
     6721 actcggggga ttctttctta tataattggc gatcgacaag ttcacgataa aattggtgat
     6781 gctcgattaa ttcatcgtgt gttccttcgc ctgttatttc cccgctttgg acaacaacca
     6841 atttgtctgc atgctgcacg gtcgacaatc gatgggcgat tactagcgtt gtcctagaaa
     6901 gcatgagttg attgagcgct tcttgtacta aaaattccga atggctgtct agatgggcgg
     6961 tggcctcgtc taacagtaaa atttgcggat ttcgcaaaat ggctcgagcg atcgcaagtc
     7021 tttgtctttg cccaccagat actaaaatgc ctctttcgcc cacttccgtt tctaagccgt
     7081 ctggcaaaga ggtaataaac gaagtcaaat ttgctttttc taaagctgcg tgaatgtcgg
     7141 catcgctgct tttttcagca tgcccataag taaggttgta gcgaatcgtc cccgccatta
     7201 gtggagaatc ttgggcgaca taggcaatct tttgtctcca ctcctggaca tcaaagtcat
     7261 tgattggttg gttgtcgtac tctatcgtcc cttcgcttgg tggataaaat cgttctatta
     7321 atgagaataa ggtggtttta cctgcaccgc tagggccgac aatcgccgtt acttcactgg
     7381 cattggcgga aaagcttaca tttttcagga tttggctgcc attcggatag gagaaagaca
     7441 cattggaaaa tcgaatgcca tttacgcggg caactgtttc ttgattgtgc ggataagata
     7501 cactagccgc taattgagat tccaaattct cctccataat ataggtgatc cgttctgtgg
     7561 cgccttttgc tttttgcaac tgcgtaaaaa agtggcccat ttgtgagatt ggagggatga
     7621 tttggaacat gtaaaaaaca atcgcaacta atgtgccggc cgataaagtg ccattggcca
     7681 cttgtatgcc tccgtaacca aaaacgacga ctaataccaa caaggtaatg gttgtcatca
     7741 atggagaaat gatggccatt atttttccgg tgtccaatcc atgttttaac agttgatcga
     7801 ttctgttgtt gccttgagat gtttccgggt cttctgctat agaagattta actaatctaa
     7861 tatctgacaa cacacgccct aaatcccctt gaaatgatgc tgtctcatct tgtaatgcct
     7921 tcgacacttt gtatgttttt ctacctagtg gttttaatac agctagcgac acagggacaa
     7981 ttaacaataa gagcagcgtg atgctccaat ttaatgcaaa cagaattata atcgaaccaa
     8041 ttattttaat ggttccagat aaaaaaggaa tcaattgatc ggtaaaaaaa tttttaataa
     8101 catttgtgtc atgagtaatt ctgctcattg tttctccgga gctgttctgg tcataaaatg
     8161 agactggcaa tcgtaacact ttgtgccata gatctttgcg taattttgcc accatgatct
     8221 gaccaatgta gatcatcata tacatggaga tgcctgacag aataatttgt acgataaaga
     8281 cgcctgcgat tagggcagct gttgtaccac tgaaatttga ttcaacagtt atgtccacga
     8341 gattcattgt taataagggg acagcaagag aaagcgctgt ttccatcagg actaaaaaca
     8401 aagctagccc aagtagccac agtgaagggc ggtaaaggcg cattagagaa atgaactctt
     8461 ttaattgaat cggtcgttca gttgtagacc ccatatgatt cttccttcct ggccgaaagt
     8521 ttgtctgata gcagtttctt gaaaggcaaa ttgttcgtaa agcttgcaaa aaaatgcgct
     8581 tcctcgtagt gctttaaaat gtttttgaag ggaacacctt ttttttctaa acatagccct
     8641 ttataataaa gaaattgccc gacatatgcc gtacaagcat aattcctaga taattgcaga
     8701 ccttgtccta tatcttttaa agcagcatca tagtggtggt agttcagttc aatgattgtt
     8761 ttttggtaca aaatatagat ttttaagttt tttttgtgca aataggtgtt ttttccttta
     8821 attccttcaa ccgatgcaag gcttttttgt aaatagtcta acgtttcgct atatgaatat
     8881 gttttcatgt gggaatggat aatgcctaaa tataaatgaa actttgtttg aatagactgt
     8941 tcaaatggca aacagccagc catgcatttt aatttcatcc atgtggtttg agcatccttt
     9001 ttcctgcatt gatattcgga gaacagatga tggatcctta tataatcttt aaaccaatta
     9061 ggaaattcca ccgcttggcc acagtcaatt aattgtgcag ttagcctgtt cagttcctcg
     9121 tactcttcat gtaaagagag ttgttcaatc atttcataag tggtttcgat gtattcacca
     9181 ttgtaggacg tgctgagcgt taaaaaatgg tcgacaggca cccctagttt agaagcaatg
     9241 gcttcaagca cgattatgtt tggaatgtac ttcccatttt caattttgct tattgctgat
     9301 tggctgacaa cgctagagct aatattttct tgcgacatac ctagtttcat ccttaagttt
     9361 cggatctcca tgccaattcg attatccatc atatgcatct tccttatcat aacctgtatt
     9421 agttggtttt tttaagtgag gatggttatc gaaagattat caggcgttta tcagaaatat
     9481 atcagatcga ccaaatttca acatgtattt cccaaaaaaa taggggctat agtagtaagt
     9541 ttttcaaaaa acaaacaaag ttattctaat tgtcataatt tataagagat actgtaaaaa
     9601 aacaggctca acatcgacat ggttcatttt tagccaatta atgactgaaa acgatatttc
     9661 cattttgcta aaatgttttt tacagttaat ttgcgccggg gattcctggc aaaaaaaata
     9721 ggggaggaat tataaaatgg aaaaagcttt tgacttggat ttggaagtag tacacacgaa
     9781 agcgaaggat gtacaaccag atttcacaag cgtcagtttc tgtactcctg gttgcgggga
     9841 aacgggtagc tttaatagct tctgctgcta agaacaaaga cttttgatta tttacatggg
     9901 attgcccctc aaaaatcttg tatttttcca aaatacagat ttataaactt gagcaagggc
     9961 aatcctgttt gtttttcatt tgaaaggggc gttcatagcg atgagaaaaa gcgaacaatt
    10021 attatatgag cctgtagaca caatcatgtt gagagcaccg attttgtcat tatcgcatga
    10081 ccatcaaaac gcgtccaaag acgatattat ccctatttta aaagaataca tagaacggcc
    10141 tgaaataaaa gaagcactag cggttgccag ccctaattta tttcagtctt tagataaaat
    10201 tcatggcgat ccccgttcca aaaaaacgag gaacgctgtt tccagcttgt taaagttttt
    10261 aataaggatg tctagccggc caactccttt tggtttgttt tcaggcattg ctataggtga
    10321 acttggcaat aagacagtag gatctttatt agacacgaag caacaccaaa agagagcacg
    10381 tccagatatg gagtggttgc ttggagtagt cagcaaaata gaaaaaaacc aaacgatcgc
    10441 taaaaagctt aacgttgttt ttaatgatgc tgtgtatcag acggacgatc gagtctacct
    10501 tcattatttt tctaactgtg gacagttacg aagcagtgaa aaccaagagc gaaaagacaa
    10561 tatctcgatc agaaaaacag tggtggtgga gtttgtccaa tcggtagcga aaaagccgat
    10621 ttcgatctct gaattaatca atcagcttca attaacatat acgagcgcct ctataaatga
    10681 aattgaatcg tttgtatgga atttattcca acaagaattt cttatcagtg aattaaggcc
    10741 gccaatcgtt aactgtgcgc ctttatccta tgtcatacaa atccttgaat ccatccctga
    10801 agcgacggaa ataggggcga tgttaaaagg aattgaagcc gatatcgaaa cgtataacca
    10861 attgcctata gggcagggat tagatttctt tcaaacgcta acggctaaaa tgcaagacat
    10921 tcatcctagc aaacagccgt tgcaagtgga cttgcgctta acatgcgcag aaaaggttag
    10981 gataaatcgg tcaattggcg aacaagtggc caatgcggca gagtggctgt ggaggctttc
    11041 aaaaaatgag actggagtcg cccatttaag ggagtaccat gttgaatttc ttgagaaata
    11101 tggggtaaat cgagagattc ctctgctaga tttgttaagc gatgagaaag gtttaggggc
    11161 gccgccaacg tataaatacc cgccttcagc aaaaagtgtc aacccgcctc aaatgaagag
    11221 cactcatcgt ttgttaatgg aaaaatacat ccagtgttta agggaaaatg caaaagaaat
    11281 aacattgacc gaatctgacc tgcaaaagct aatggataac gacacagatg acgtttttgc
    11341 tcccaattct ggggaattat ttgttgaagt gcttgcttca tcagcagagg aagttgataa
    11401 aggaaactat cagttggcaa taggaaccaa tgtgggctcc caagagctag ggcaaacatt
    11461 cggccgtttc tcggatatga ttgctagcga agagaataga aatttgatgg aagaacaaaa
    11521 gaaaatagag gaaacatgta cggacgttga aaccgaatac gtagagttga gttttctgcc
    11581 ccaaagtggc cgtgcaagca acgtttctat tacgcattcc acacggaatt tacatacgac
    11641 tattgccacc aatgcaaacg gccaaaacaa aaaattgttg ctagaagata ttttggttgg
    11701 ggcgacactc gggaggttct atttaaaatc gaagaagtcg aataaacgtc tcgtatttac
    11761 gtcaaacaac atgtttaatt acgagagtgc accaaattgt tttcggtttt taagggaggt
    11821 ttctttagaa gatggaaagg cgattcaagg ggtgaatttg ggaagcctta gagagttcac
    11881 ttttattcct agaattacgt ctggaaaagt cattctttca ccggcaattt ggaaattaaa
    11941 cgatcaaata gaagaattat ctgatttttc tatgcctctt gaagaatgga tagagcaatt
    12001 ttcaacatgg atgaaaaaaa tgcaggtacc agaacaggtc tttatggctt atggggataa
    12061 ccgattgtac atccacttaa agaatgccaa ccatatgcag gaattaaggt cggaactacg
    12121 gcgcagagga cgggtacagt tacaagaaat catcggcggt tatcgggaga agcagtgggt
    12181 aaaaagccct ttaggcagac ataatgctga atttattgtt cctttcaaga aaaggcctca
    12241 tgtgcccgca aaaccaacgg tgatgattaa gccagttgca gaagtgccaa ttgaatgcag
    12301 ggaaaaagaa ccggggacgg actggcttta ttttaagctt tacgggccta tccacaaaca
    12361 gcaaaaactg atttctacac aaattccaac gcttgtagcc gagttagaga atcacaaact
    12421 cataaatagc tggttcttta ttcgctatta tgacagcgag ccccatctgc ggctaaggtt
    12481 tcacggagat ccgaaaacct tgttggctgg tgcactgccg gtatttcaaa aatggtatgc
    12541 agcccagcgc cttgcgggga acgttaaaaa agttgtaatt gagccatatg aacgggaaat
    12601 tgaacgatac ggcggccttt cgcttatgcc tctaatggag cgatactttg aaaaagacag
    12661 tttgttgaca tcaaatttgc ttggattgag tagtaagcaa gcactgaaag aaccgctaga
    12721 attaatcgca tccatgtatg ttgtttattt tctaacggag tacggttggc accatgaaag
    12781 gcaattggag tggatttcca agtggagtga ggatccagct tactccaagg agtttaggcc
    12841 ttatcggaat gatgtgctta aatggctaga tcaagaagaa aactggaagg ctctaaagga
    12901 gcagaaaggc tttctcttta agctgttttc taaaaacgaa gcaatcatac acgagctatc
    12961 ccataatatg gagataacgc cgatgaccaa tacagaggaa agagttgtcg ggagcttgat
    13021 ccatatgcat tgcaaccgct tgctcggcac agaccgtgat agggagaaaa aagcaatggc
    13081 gtttgtgcgc caaattattg aaagtcaaaa gcattggaac aaaacgaaag ggcgaccatt
    13141 aaacgtatga ggtgatccac cgtgatagag aaggtagttg atgaccaaga aaaacaagaa
    13201 acgaaacgaa ttattgcccg tttgaccgag aaactaaacg atccacaaaa agtggaagag
    13261 attgtaatgg ataagaacaa tgtcacgacg attagcaaag taaatccgtg ggaccctgtt
    13321 tctttatctc atggttttgc aggaacgatt ttattcttct ctgaattgca taaaatgtat
    13381 cctgaagaga agtgggatca tgtggcccat aatcatattg tctacgctag caactatcta
    13441 aaaaatgggg tccattctat ctctttattt ggtggaatta caggatttgc tttttctgtg
    13501 ttcaatgcat ctgaaaatgg tacaagatac cagaacttat tggcaaaact ggatgaagtg
    13561 attcgtaggg tagcagagaa tgagatcgaa gaagaaaaac aaaggaatgg tctcggcgct
    13621 ctaccaactt tttatgatgt gatccaagga tattctggaa ttggaaggta tttgcttgaa
    13681 agaagaaagg atacgccagc ttttaacggc ttaattgaag cgattttgcg ccagtttgtt
    13741 gaaatgactg ccaccataac atgggaagag catgaggttc caggatggta tgttacgcaa
    13801 gagaatcaat ttttagagaa agataaaaag atttatccat ttggcaactt caatttgggc
    13861 cttgcccatg gcatcccagg gccgttaagt tttttatctt tatgtctatt aaaagggatc
    13921 gagataccag ggcaaaggca agcaataacc acgattggca attggctcgt ccgtcatgcg
    13981 aaaagcaatt caactggtgc cccagtttgg gcccatcgcg taggtgtgaa agaagctata
    14041 gcgaacaaat ataccgttat agatgaacgg gaaggctggt gttatggcaa tcctggtgtt
    14101 gcccggtcgc tctatttagc agggaaagcg ctgaacgatc ttccctatca ggaaatggcg
    14161 gttaagtgtt tccacggtat taaggaaaaa acattagaag aactagactt gcaaagtgcg
    14221 acgttttgcc acggaaagag tggtttgctg caaatcatgg tacggatgaa aaacgatctt
    14281 aacatcaatg attttgacaa gctcatcaat caattggaaa acgggattaa ggaacagtat
    14341 agggatcagc atccgttggg atttaaagat tttgaaatcg gaagccgaac aaacgagtta
    14401 gataaagcgg gcttattgga aggggcagct ggcgttggat tggccttatt gtcgaggacc
    14461 ggtgacgaca gtgagctctt ctgggataaa gcgtttttaa tcagttaggg gtgaggatgt
    14521 gccggaaaag gaagaaaaaa acatactagt cggaatttct ggatcgatct ctgtcataaa
    14581 catgccctcc tatttagctt tttttaaaca tacgtatggt catgtcaagg tcatcatcac
    14641 agagcaagcc aataagttgt ttcctgcttc ctctttgtcg ttgttttgtg atgacatttt
    14701 tcaggatcac aatgaaacga tagatccaaa tacggccagc catgtcgggt tagctaggtg
    14761 ggcagatcta tttattgtcc ttcccgctac ggcaaataaa atcggccaag ttgctaatgg
    14821 cttaggcatg gatcttctgt catcaacgat attggcttct acgaagccgg tgctcttttg
    14881 cccaaacatg aatgaggcga tgtggaacaa tttttttgta aaaagaaata tagcgttgat
    14941 taaagaggga ggacatatta tcatcccccc agtggaaaaa gaagcatatg aagtggcttc
    15001 aggaagcatt cgaaaaaact ttattattcc agatatgtat accatcgctc aagagataga
    15061 taaagccatg gctgtagaag aaaatagcta ggacgccgta cggtacgtcc tagctttttt
    15121 gttgttttgg cggatgttga atttgatttt tttctgatag ggaaaaggga taatcatttt
    15181 tagaaaaagg agtgatagcc gatggaaaag atcattgaaa caaagaattt aacaaaaaaa
    15241 ataaaaggaa aaccgttagt ggaagaaatc aacctttcca tcgccaaggg agagatctgt
    15301 ggtcttatcg gtcctaatgg cgcagggaaa acgacgatta tgaagctgtt gacgggattg
    15361 ctcatcccta caagcggaga agtgaaactg aatcaatgga atgtgcataa gcagcgaaag
    15421 gaagcgatgc gttctgttgg cgccattatt gagtcgccca ttttctttga attcatgacg
    15481 ggtcgcggaa tgctcttaaa ccttgccaga ctccatgggt tgaacaaaca ggagcgacag
    15541 gataaagtcg cagaagcatt gacgattgtt ggtctagatg gccgtggcga tgaaaaaata
    15601 cggacgtact ctttaggaat gaagcaacgt ttagggatcg ctcaagcgct gttaggcaat
    15661 ccagagattg tcatattgga tgagcctgcc aatggcctag atccaatggg gatgagggaa
    15721 ttgagggaat tgattttgca attaaataaa gaaaaaaata tcacattctt gatatcaagc
    15781 catttgctcg acgaactcca aaagatatgc agcacgcttg ttattattaa gcagggaaat
    15841 gtcctttttt atggaaaaca agaagagatt tatgacaagg cagagaataa tttagaagat
    15901 atttttattg ggatgatgac ataatgggac aactaatcat tagtgaattc gaacggttat
    15961 ggtcgcgatg gtccattcgg ctgctagtaa tgaccttgcc gctattagtc attgttactg
    16021 gtgtttattt ccaaaaccac aatcgaaaca ggtcaatgga tgctgttgat tacgcaacct
    16081 ccttaaattt ccctattctc agcttatcgg agcatttgtt tattacgttc aacattctgc
    16141 ttatttttat ttgtgcctat gtgataaccg aggagtatca acaaaaacaa atcaaattaa
    16201 tagtgcttcg ggcttattcg atgagccaaa tttttctgtc caaattcatt gtaatggcca
    16261 cttccttatt tatttgtttc tttctttctt tattacttgg cctccttctt cgctgggcag
    16321 atcatgtttg agatgcctga aaggtcaatt ctttttgttt ctgaagcaga cgttacaaat
    16381 acagagatgg ttctttatgg attgaactat tatggcattg cctttcttac tagtcttgcg
    16441 gtgctctcgt tattttgctt tatcgcgatt ataatgccct ctgtcaatgc tttattagga
    16501 agcggcattt gcatcctttt cttttcgatt gttggtccgc agctgttaga gcaatcaact
    16561 gcttttgccg aagggagcaa tatatcttat gtggtgtacg cctccataac aaaaattcaa
    16621 tacaccggta tctcgttatt gctttcaggc ggggaattga gcggttggct aatagccgtt
    16681 acttcgtttt atttgttggt ctttcttggg ggcgcgtatt tggtttttac tcgccgaaat
    16741 tattatgtgt aaaggagccg tatgatgaaa catttaatca taagtgaatt ggagcggctt
    16801 tggaagatga gaatgatgaa aatcctcttg ttgctgctcg taggcatctc ctttttttcc
    16861 gcttactttt tgacttggtt cgatctaggt ctttatactg cagatagtga aacgccgtta
    16921 aatgctgtta actttccctg gtttttgtta agggaagtct ctttctttgt aacactagtc
    16981 atcatgccgt tgttttgcgt ggttgttttg aactcaccaa taaaagcaaa aacgtacaac
    17041 ttagtgttgt accgtccatt tcaccgttta gagtttttac tgtctaaatg gggaacgctg
    17101 cttctgattg ctgtcttcat caccgtgttt atttggctca ttggtgttat gttaggcttt
    17161 ttcttttacc aagttccaga atacgtgact ttttatggtg accttacacg ctattccata
    17221 ctgaatggat acatttattc agctaagctc tattttttgt tttgggctgt cattgccgct
    17281 ggaattgcta ttgccagtgt gatgtcgatt atggcaccaa acccgattat tgcttacttc
    17341 ttattaatga ttgcctatgt ggtgccaatt tatttttcaa atgagctgac attttttttg
    17401 atgcccactc aatccatttt tatttcgctt tcggaaacga acatgccatt gctttacatg
    17461 gcgttgccgt taattgttct gtttggcgga gggatttcaa gtttattatg ggtaaagcaa
    17521 gattttaaat aaatgttttg tgaggggata aaatggagca cattctgatt gtcgatgatg
    17581 aaattcaaat tacttcaatt gtgggagagc tgttacagga agaaggctac caaacaacag
    17641 tcgccaatga cggaatgaac gcgataaagc tgattaagga gcaggatttt gacttaatca
    17701 tcctcgatat catgatgcct tatgtgaacg ggttagatgt ttgccgtagc gtaagggaat
    17761 ttaccgatgt tccgatttta tttgttaccg ctcgaacaag tatgaacgac caaattaatg
    17821 ggctaaacat agggggagat gactacataa acaaaccgtt tacccatgaa cagctacttg
    17881 ctagaatcaa aactcattta aggcgggaaa aacggaagca acaacctaca gatgaactcg
    17941 tctatggaaa aataaaactc gaccggcgga caaatgagct ccgctatggc gaaaccccat
    18001 tgttgctcac aaacaaagaa tttaaaatta tggaaatgtt aatgagcaac ccaaggcaaa
    18061 ttttttcgaa agatcatcta tacgagacga tttggggagt agaagcaact ggacaatcac
    18121 acacggtgac agaacatatc cgaaatattc ggatacgcat tcataaaatt gatccaatgg
    18181 caaatctgat ccatactgtg tggggagtgg gctataaact tgaataaaaa aagaacgtcc
    18241 attaaacagc aaatccgatt aacaatagcc aagacgattt tattaagttt cttcgctacc
    18301 atcattgtcg ttttggcaag ttgggcgatt gtcatgagca tcgatgaccg ctattatgcc
    18361 aattactatg agagccaagt cccccaaata accgatcaag tacaaagctt gaatcgtgag
    18421 cttgtcaatt cgcaagcgtc gggggccaaa caattagaag agatcattcc caccccaggc
    18481 atggaatacc aagtgctgga cgaacaagga acattcttgt acggttcatt ttccgctaac
    18541 gtcaacccag aaggcgtcca tttgttaaac aaggtcaaca aatcgttttt ggaagagaac
    18601 accgccacat cgtttattcc gattgtggac caaaatggta catttgctgg cagtgtcgta
    18661 cttcaatata aactggaatc ggaagttgaa gccttattta atattttttt tgtttgtcta
    18721 ttcctcacgc catttttctt tattatgatc tttacctatt attatgcgag caaactagga
    18781 aaaaactatt acgcaaggat tcaaaaattg attgtcgcca cagaattggt ccgaaagcaa
    18841 aatttagatt ttgaaatcga ggctgacgga aacgatgaaa tcacaaaact ttcgacttca
    18901 ttcaatataa tgaaacaagc gttgcaagac gctctttacc agcaatggaa cttggaaaaa
    18961 aaccgttccg agtttatttc gtctgtctcc catgacttaa aaacgccatt gacgatcatg
    19021 aaagcaaacg cgcaaatgtt ggagagaaag ataaaagatg agcagcataa aacgtatatt
    19081 gcgaatatga tcggcgaaat tgagaggacg gaaaacctcg tacaagagct tggtacaaaa
    19141 atgaacgacg aagagtcttt ttttgccatt gaaacaaaaa ccgtcgaacc aggtcatttt
    19201 tttaaaactg aatttgcaaa gtacaaagat tttgttcaaa acgaaggact ggagtttcac
    19261 acttccgttc tcgactacag aaaaacagcg aacacgattc agatagatgt gcaaaaaata
    19321 acgcaagtga tagacaacct catatcaaac agcttacgct tcgctgaacc atatgatggg
    19381 catattgatt gtcacgcaga atgccatgac gattacgtaa aagtgactgt aagcgacaat
    19441 ggaaaaggct tcactgaatc agacttgcat tacgtctttc aaaaatttta ccagaataac
    19501 gatagtgctg accctcataa aggacttggg ctttacatcg tcaaacacat aatcgaaaaa
    19561 catggcggaa acgttcaagc atggaatgac aaaggcgcag tggtttcctt tcagttacct
    19621 gctgtcccga aaaacagcca ctagcatttt gcgctagtgg cattaacttt cagtggtttt
    19681 aatcaaagca cacaattcct tggttttcaa tcgcttcggc acgggcatcg ccaattcctt
    19741 taattcgttt catatcatta taagaggaaa agggccggag ttgaataatt tgtgcggctc
    19801 gatctggacc aatttcataa atcgcttgca gcttagactc ggaagcactg ttgattttca
    19861 ccgttccagg cccacaacta ttggtacttg cgctttctga agactgtgca gtctctgttt
    19921 cagtggtagc ggtttcattt ccgttattag tcgaggcact ggccacttct tcttccaact
    19981 tcgagatagt cgtttccttc tcttcaatcg tttgctcttt ttctttgatt ttatcgtcta
    20041 atgcagcaag cttgtcctca taatcttcac taatttcagc agtgatgcgt tcttccagtt
    20101 cttcctcgat ctgttcccga aattcctctt cccattcgag ttttgcttcc tctaattgct
    20161 cttcaaaaga accgtcaacg tcgccttctt ccgcctgtag gagctccaac tgctcttcag
    20221 actcttttaa tgattcctca gcttcctcta acgcaacagt caattcttcc atttccgttt
    20281 ctttgtcttg taaggatgct tctaaggttt cgatttttgc ttgcgaacga tctagttggg
    20341 cggactgggc tttatttgga tcttgcgtac tgtcatgtaa gatagaagta acaataagta
    20401 ctggaatcac gtataaacat actcgacttc ttgacggtag ccggatcaag ctcggtttaa
    20461 tcaatcctag aataaaagca aatagggaaa gtgccgccaa aatgaaaaat aacgtattca
    20521 agctagttcc tcctttgtgg tgtaatatgg taattgtaac aaactatcag actatcgtca
    20581 tgggttaatt tgcgtagggg aggagttgat ttgtttatga gttcttatat aagggacgcg
    20641 cacctatgat gcacagccat gttctattca aaataagcat tgtgtgaaac gattgacagg
    20701 tgtacttttt ttaaggacgg tgtgttgata tgaaagattt tctttcgagc gcttttctta
    20761 tttgtggttg gctttgtatg gctattagtg cctatctact gttttggaca gtggtaactc
    20821 ccttatgggc catcatccct tttctcgttt tcattagtat gggtctatta tgttttcgta
    20881 tttctaaaaa actaaataat agaagaaaat gaacgttttt ctctcaatag tggaagatct
    20941 aaggtagcta gaaaaacact agtgccgagt ctctcataac taccttaatc aattggtata
    21001 actactggta acgtttactg atttgaagta aactaatgga aaagacctgt gtaagaagtc
    21061 gtttttttat taaatatctc agctgattgt ctggtaagga gagcatgtaa tgccaaagct
    21121 tgaattcaag gatataccaa acagaaacaa ggagaactgc gatgcaagga actgaccgta
    21181 ctgtgatgat gcattttcct aatagtcaac aagcatcttc attaaaaatc atccaagaac
    21241 caactagtca aattcgttcg ttttatttta aaaagagttt gttggcacaa gtggaagaac
    21301 ttgagtatgc aaacaactac gctatttatt ttctattttc tgatttagag aatcctagtg
    21361 tgtacattgg ccaatcaacc caaggaatta aacgactgag agaccatcta cgagaaaaag
    21421 atttttggca gtatggcatc ttatttgtaa ctgataataa cagctttgat aagctggcca
    21481 ttgatttttt agaacaccaa tttattcaac tgtttaaacg ctcatccttt attgttgaaa
    21541 accacgacct gcgtaataca aagccgacaa ttaattggtt tgcccacgcc accatgaata
    21601 catttacgaa tcaaatcaca tttcttcttg aagcgcttgg cgtttctatt caagaagaag
    21661 agaaagaaaa cgatcggaaa ctttttcctg ctgaaggaga aagagaggct tctttataca
    21721 tacatgatgg ccagtttttc ttaacaaaag gatcaatcct tcatcgtcca caggaacgtc
    21781 tgaagaactg gaatgatcaa gggaaacttt attataagct gaatgcgcgg attgaccagc
    21841 taattgatgt aaagcaagca gaagtgattg acgaaggcac agttcgtctt cttcaggatg
    21901 tcgtctgctc aagccctagt gcagcagcag atttatgcag tgggacttct aagaatgggt
    21961 ggacgttttg gaggggactt gaggaggaag ggaagaattt tggtaggtag ttataaattt
    22021 cgtaatgaaa ataaaaaatt atggaagagg gaagaggatg aaattaacta aacatgattt
    22081 ttattttgga tctttattat cattacttgt caaaagtgga tttgcaccgg cgattattga
    22141 cggtggagag ctaagtagaa tttattcctt atcactggat caaggtgaca ttaaagtcta
    22201 tgcaaaatat tcttcaaaac cttgtaatga aaaaaaagaa gagcaaaggt gggattatca
    22261 ttttagtaaa gaggaagtaa ataaaataga aggattaatc aaagataact cattaatttt
    22321 tgctctaatc tgtgggcaag aacgtttaaa aaatagtgaa ataactttct tagatataga
    22381 tcaactaaaa gaatgcttag gctcggcata tcgtgaatca aatcggcgtg tatcgataaa
    22441 ggtggataaa aggggacgaa gtttttatgc ttatggttca ggtttagatg gggtagaaaa
    22501 acctattaaa atcaaaagaa atgcgaaaga gaggcttaag gagttctttc caaacctaga
    22561 taattttcaa atcaaagaac aattaagcca aaaaagaata gaggtataat ctcaccgaat
    22621 caatatctga aataattaca tgaaaataca gaaattattt tttcggacat tttttggggc
    22681 ggaaaagaca ccgtataaag gggcgattgc tatgcaacgt aagtgatagc atctacttaa
    22741 acctcaatat ctcattcata tcatcaatat ccaacgcatc agcaattttc tcaatatgtt
    22801 caagttgaat tcgttcgcgc ttcccgcttg ccatttcgct gagcgtggcg cggcggattc
    22861 ctgtttttaa atggagggcg tgaatggtta attgatgttt atgtagcaaa tcgtttattg
    22921 caatttcaac tttacgcata aggatcacct tctattaata agtacttgct gtacttataa
    22981 gcgtacggta tactatttcc aaaagttgta cgcttatacg tacggatttg aggtgatccc
    23041 atgcaatccc gccaacagct cattcccgac ctcctcacag aagctgctta tcgaatggaa
    23101 acgactttca aagcaaccag tccaaacatt tgcaccacga ttacatacaa cgctcaaaaa
    23161 tccaacatat acgccttgct ccagcaacga attcatgctg actatccaac agacattctc
    23221 tgtttcccac accaagacat tcccatcaac agcaagcatc caatttggct catatccctt
    23281 catccatgcc agcatgagct accacaacag ccagacgttt atgtcctatc gatagcactc
    23341 gcccgaagca gggaacttta ttgttcctat atttatgatg tttcacggaa aaagctatac
    23401 tacgcgataa agggaggcgg tgctttccta aatgaacagc ggttgcgacg ggaggaaatc
    23461 atgccgttaa atgaagcggt tttgcggatt aaagcagact atctccacga aagcaataaa
    23521 agggttccgg caaataagag ggtaggtgtg gctgatcagt caacggcttt ggaaatttgc
    23581 cgcgttgcag aagggaaaac cgatctgttt atggctatga gcgaatctcc ccatgcgttt
    23641 gcagcggcaa gtctcatcgc agaagaagcg ggagtaaggt taatgacggt ggaaggcaag
    23701 cccttgcgtt ggtacaaaga aagcagcttt tgggttgggg tgatttaaat gagttacaca
    23761 cttaaagatc ctctacatgc caaacttgat atattgaatt aaagacgtag gaggaatgaa
    23821 gtgtgtcgtg ttacataaag tggatcattt aaaaagagaa ctcgatgcac gccgccctct
    23881 tccaatggca actgtccaat cattgaagaa agatttttta gtgcgaaata cgtatcactc
    23941 caatgcgatt gaaggaaata cattaactat ttttgagaca aaagctattt tagaagacgg
    24001 cattgtggta ggtggcaaat cgttaagaga acatttagaa gtaattaacc ataaagaagc
    24061 tagtctttat atagaagaac atttagagga agttgtgaca gagcgtttca taaaagagat
    24121 tcatgccctt gttcttagcg gaattgaccg gcaggcagcc ggtgcctatc gaaaaagagg
    24181 aagtacggat agctggtgcg acccataatg tgacttcaag ccacctcatt caagatgaga
    24241 tggggcagtt ggtgcaatgg tataacgaga gcaatcactt gcacccgatc gagagggcaa
    24301 gccgtttgca cagcaagttt gtcaatatcc acccatttcg agatggcaat ggaaggacag
    24361 cacgcctgtt attgaacttt agtttattgt cagcaagtta cttgcctgtt tttgcttaaa
    24421 gtagaagacc gaatatcgta ctatgaagcg cttgatttag aaggagccaa gggggagtgc
    24481 agacctttta ttaagatggt tgctgagt
//
