LOCUS       NZ_AP023360            17087 bp    DNA     linear   CON 25-AUG-2024
DEFINITION  Catellatospora sp. IY07-71 chromosome.
ACCESSION   NZ_AP023360
VERSION     NZ_AP023360.1
KEYWORDS    RefSeq.
SOURCE      Catellatospora sp. IY07-71
  ORGANISM  Catellatospora sp. IY07-71
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Catellatospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Catellatospora sp. IY07-71
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8595826)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 381x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326265.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 05:22:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,732
            CDSs (total)                      :: 7,655
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 20 of 92
            Pseudo Genes (incomplete)         :: 82 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:09:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8578739
            Orig. end                         :: 8595826
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023360.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..17087
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="30"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..17087
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17087
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:12349](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12349)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(606..1829)
                     /locus_tag="CS0771_RS38380"
                     /old_locus_tag="CS0771_77390"
     CDS             complement(606..1829)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CS0771_RS38380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CS0771_77390"
                     /product="YncE family protein"
                     /protein_id="WP_212845506.1"
                     /transl_table=11
                     /translation="MTTRREALALFGAGAAAVLTGCGPAGPEPAASAPDLVLAQVAEGL
                     AVLRADGVERLGAGLAAPDGATVFAARAEGVDTVLSTIELRTGRRTPGPRLAGAWVPRV
                     ASADGRLVALAAPDSAGVTHVPAGRARTPLVVAGTTAEVARLELTGNLVPDAFTAGGEG
                     LFVLDWLPPAAPDRYRVRHLDVASGKASRLLTRLKAAVPDGAEEEMSGEGRFAVYAPDR
                     QVLYTLYTHQPDHTHTRDLVAGRRSNVHAFVHTLHLTEQWAFCVDLPAPFGEGPGTAHT
                     LAIAPDRSELYVLDVSSGTYAVIDTGQLTVRSTAKGPRAAGTAYAAATFDALYVAVGES
                     VHTTPRTGVSAWRTWTAGGSVSGLAASPDGRRVYAALPGRIAWFDAATGARLGEHPVPG
                     LTGLTRVL"
     gene            2010..2762
                     /locus_tag="CS0771_RS38385"
                     /old_locus_tag="CS0771_77400"
     CDS             2010..2762
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028300.5"
                     /locus_tag="CS0771_RS38385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77400"
                     /product="CBM35 domain-containing protein"
                     /protein_id="WP_212845507.1"
                     /transl_table=11
                     /translation="MEDDFGYEGRRRRRFTVLERLRLLPLVATTVFTGALILLIVTTVR
                     QPASWNDALPWQDAPSPAPAAGAPIAPDVPLAHTPAPQRSGVRASAAPSTGTAAPTAAS
                     PGASSPAPPPSPTPPPAVQRTVRYEAENAAGSRARFANDHRNYSGNGFMDYENTSGSYL
                     QWTVQADAGQATLRLRFANASGRNRPMDISVNGTVVARDVRFDATRDWDDWASATVTVT
                     LTGGANTIRATAVSGDGGPNVDCLDLTQ"
     misc_feature    2013..2024
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     gene            complement(2767..3738)
                     /locus_tag="CS0771_RS38390"
                     /old_locus_tag="CS0771_77410"
     CDS             complement(2767..3738)
                     /NRPS_PKS="Domain: PKS_ER (18-320). E-value: 6.8e-45.
                     Score: 145.5. Matches aSDomain:
                     nrpspksdomains_CS0771_RS38390_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658165.1"
                     /locus_tag="CS0771_RS38390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77410"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_212845508.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-10, bitscore: 39.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.2e-22, bitscore:
                     78.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAIQITQYGGPDVLIPAEVDPPAPGPGQALVEVAAAGVNFIDVY
                     HRLGRYPTPLPFVPGVEAAGRVLAVGPGVTEVRAGERVAWALLPGTYAEQAVVPVDRLV
                     PLPDGLAEETAAAVLLQGMTAHFLTHDVYAIQPGDTVLVHAAAGGMGLLLCRLIPHLGG
                     RVIGTVSTDAKEKLAREAGAAEVIRYDQVDDLAGRVRELTGGAGVAAVYDGVGASTFDA
                     SLASLRRRGTLALFGAASGPVPPVDPIRLMQAGSAVLTRPTLGDFVVTRQELLERATDV
                     LGWVAAGTLRVSVGGRYPLAEAARAHEDLTSRRTTGKLLLIP"
     aSDomain        complement(2779..3684)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CS0771_RS38390_PKS_ER.1"
                     /evalue="6.80E-45"
                     /label="CS0771_RS38390_PKS_ER.1"
                     /locus_tag="CS0771_RS38390"
                     /protein_end="320"
                     /protein_start="18"
                     /score="145.5"
                     /tool="antismash"
                     /translation="EVDPPAPGPGQALVEVAAAGVNFIDVYHRLGRYPTPLPFVPGVEA
                     AGRVLAVGPGVTEVRAGERVAWALLPGTYAEQAVVPVDRLVPLPDGLAEETAAAVLLQG
                     MTAHFLTHDVYAIQPGDTVLVHAAAGGMGLLLCRLIPHLGGRVIGTVSTDAKEKLAREA
                     GAAEVIRYDQVDDLAGRVRELTGGAGVAAVYDGVGASTFDASLASLRRRGTLALFGAAS
                     GPVPPVDPIRLMQAGSAVLTRPTLGDFVVTRQELLERATDVLGWVAAGTLRVSVGGRYP
                     LAEAARAHEDLTSRRTTGKLL"
     CDS_motif       complement(3136..3156)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CS0771_RS38390_0003"
                     /evalue="5.80E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="CS0771_RS38390"
                     /protein_end="201"
                     /protein_start="194"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="LAGRVRE"
     CDS_motif       complement(3283..3327)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CS0771_RS38390_0002"
                     /evalue="3.40E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="CS0771_RS38390"
                     /protein_end="152"
                     /protein_start="137"
                     /score="19.6"
                     /tool="antismash"
                     /translation="GDTVLVHAAAGGMGL"
     CDS_motif       complement(3526..3561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CS0771_RS38390_0001"
                     /evalue="1.20E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="CS0771_RS38390"
                     /protein_end="71"
                     /protein_start="59"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GVEAAGRVLAVG"
     gene            3833..4108
                     /locus_tag="CS0771_RS38395"
                     /old_locus_tag="CS0771_77420"
     CDS             3833..4108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018349593.1"
                     /locus_tag="CS0771_RS38395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77420"
                     /product="dsRBD fold-containing protein"
                     /protein_id="WP_212845509.1"
                     /transl_table=11
                     /translation="MTTATMTKTLMVELRFEEDVDLTRATASMRLPNGRLLVGEGQARR
                     NPVDRPRASIGEEMAGARALSGLAHRLLEAAADEVESNVHGGDPAI"
     gene            complement(4297..6411)
                     /locus_tag="CS0771_RS38400"
                     /old_locus_tag="CS0771_77430"
     CDS             complement(4297..6411)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018792120.1"
                     /locus_tag="CS0771_RS38400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77430"
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="WP_212845510.1"
                     /transl_table=11
                     /translation="MAEDRAQLRERAEAVLRRLAGEHAVLRADQWRAIEALVADARRVL
                     CVQRTGWGKSAVYFVATALLRGRGHGPTVIVSPLLALMRNQVEAAGRAGIHARTINSAN
                     LEDWAQITAEIADGSVDVLLISPERLNNPDFRDGVLPRLAATTGLLVVDEAHCVSDWGH
                     DFRPDYRRLRTMLDELPAGTPVLATTATANARVTADVAEQLGDALVLRGRLDRESLRLA
                     ALRLPSPAHRLAWLADHLDRMPGSGIVYTLTVAAAQETAQFLASRGYAVAAYTGQAEDA
                     DRRAAEQDLLDNKIKALVATSALGMGFDKPDLGFVVHLGAPASPIAYYQQVGRAGRAVA
                     SADVMLLPGPEDTAIWRYFASLAFPPEDQVRGVLRALADAGRPLSTQALETQVDLRRNR
                     LELMLKVLDVDGAVRRVRGGWEHTGLPWAYDAARYARIARARQDEQQAMLDYAAATGCR
                     MEFLRRSLDDPAAGPCGNCDNCTAPAFTADVSAEALRAAQTFLGRPGVEIEPRKMWPTG
                     LPAVGVPLSGRIPPAEQTHPGRAVGRLSDLGWGGTLRTLLADGAADQAPPQDLLAVLIE
                     VLKDWSHGDSPWPARPTGVVAIDSTTRPRLIQAVAQHVSRVGRLPFLGTVTTTAQPGVH
                     RANSAQRVKALHGAFTIPDALAAQLREQTGPVLLIDDLVDSGWTMAVVARHLIQAGAPG
                     VLPLALALAA"
     gene            6485..7447
                     /locus_tag="CS0771_RS38405"
                     /old_locus_tag="CS0771_77440"
     CDS             6485..7447
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016811682.1"
                     /locus_tag="CS0771_RS38405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77440"
                     /product="TIGR03557 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_212845511.1"
                     /transl_table=11
                     /translation="MTNYGYTLMCEQRGPRDLVDDAVRAEAAGFGFAVCSDHYYPWLDE
                     QGHAPFAWSVLGAAAHVTDRIGLVSFVTCPTMRYHPAVVAQMAATVGVMSGGRFTLGLG
                     AGENLNEHVVGAYPQATQRHAMLAEALDIIKPLLAGETVHHSGEFYDVPEARLWDLPEE
                     RVPIGVAVSGPSSCRLAARHDAAMIAVEPKAELIEAYEKSGGNGRPRYGQVALCWGPDA
                     DACAQTAYEQFRWFNLGWAVNAELPGPRAFDAAAAAVTPEYVASKIPCGPDVDRHVAAI
                     REFTDAGFTDVAVLQIGGDSQPEFLDFAHKELLPALNGG"
     gene            7502..8188
                     /locus_tag="CS0771_RS38410"
                     /old_locus_tag="CS0771_77450"
     CDS             7502..8188
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CS0771_RS38410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CS0771_77450"
                     /product="hypothetical protein"
                     /protein_id="WP_212845512.1"
                     /transl_table=11
                     /translation="MSSSALMLLGGVPFTLLAIAFLSLLARMQAAADGRPVRLNAAARE
                     RLSAEAQELEEVAAEVLEAARTAVLKAEKTAAELAAAEAERDTAWQAHLDAAGRLEEAG
                     EALQAQPAPEEPAVSEEAVREISRAARDAYKRGDLTIEQLRAVWQQVDGWDQARQERSH
                     ELSRLRAEDAEASRLYQVAASRERAARRAAEVARVSSHALTQEAADAAYEAQALQTLLR
                     KGRRAR"
     gene            8225..8500
                     /locus_tag="CS0771_RS38415"
                     /old_locus_tag="CS0771_77460"
     CDS             8225..8500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735556.1"
                     /locus_tag="CS0771_RS38415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77460"
                     /product="DUF6158 family protein"
                     /protein_id="WP_244871280.1"
                     /transl_table=11
                     /translation="MRDYDEVVEIVYAWQQDTGEGVPARDLSDEDLFRELAALYRTRLD
                     SLRHASDQALTRHTTRTVELETDYVRRFPDREINPDRLRSGARTRS"
     gene            8687..9799
                     /gene="dusB"
                     /locus_tag="CS0771_RS38420"
                     /old_locus_tag="CS0771_77470"
     CDS             8687..9799
                     /EC_number="1.3.1.-"
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="dusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688414.1"
                     /locus_tag="CS0771_RS38420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77470"
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="WP_212845513.1"
                     /transl_table=11
                     /translation="MLGRIPVDPPVVLAPMAGITNVAFRQLCREQGAGIYVCEMITTVA
                     LAVRNPKTEKMIEFGPDEQPRSMQLYGVDPDITAKAVRRVVDENLADHIDLNFGCSVKK
                     ITSKGGGSAIPWKRRLFGSIVKAAVDAAAPAGIPVTVKMRKGIDDEHLTYVEAGLIAQE
                     AGAKWVALHARTAAQRYSGEADWESIATLKQALDVPVLGNGDIWEADDALRMVAETGCD
                     GVVVGRGCLGRPWLFADLAAAFAGRPERVMPSLGEVALVMRRHAELLTLWWGKEREAVT
                     DFRKHVAWYLKGFPVGSELRRSMAMASSLMELDDLLGKLDHEVPFPEANLGQPRGRTNS
                     PAKVVLPYGWLDDRDSEAVPEDAEHDDSGG"
     gene            complement(10001..12349)
                     /locus_tag="CS0771_RS38425"
                     /old_locus_tag="CS0771_77480"
     CDS             complement(10001..12349)
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="CS0771_RS38425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77480"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_212845514.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-41, bitscore:
                     140.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETATEVRRPFPFGREDLDPERIGLGVRQTLDHYFHWRDGSPGV
                     IAAHVDGYTEQLRAILSRHGTVATLQRAAWPPRRRREQRAQAVRELNYFGVYNLSEIPD
                     PADVARAERLARVHAGAVRDTLAAIERGHGPAGVVEALEARFPGLRGVPETRWLLARLD
                     RLHRCLPDTVVRAGAMGKVVRTLAGVLAIGAYDTRDAGRAATRAHLTRILPGAYAYGAA
                     YAIVDDSFQDLRGAHIPQADRDRLHRLILRGLSTGGTVDRAEIPDHPLAEELHELYGVA
                     LDVYPFGTHRHLYQAAESMYLAQHRDAEQPPEGGLDAAYPDIFLKAGLSRVVANLLGRR
                     EVDEGFYARCLNTIFLSQFKDDLADRDEDRRAGRLTPFTLPAAARAGGRADPLYDLFAY
                     DAYVVEQVYGGDPAARDALIGIGTVKLAAFLCRDPHTTLALLDEYPATAQIAAFLRTAA
                     AVPRRALPHLTTGDLRLKREAAAIMGERDPNSVDARTFVLDRLERINELVHECHTGVDA
                     GELAPILAYTMDGPAKRLRPALTLMLAEGLGVADTLSEPLLGAIELFHTASLIFDDLPA
                     QDDAALRRGRPAAHTVFDEGSVQLAAISMLSSGFGMLARLDRHYPAQRVTDVIEYVGKV
                     LGPQRLCRGQYLDLRFARDARPVTGEDILEMYRLKTSTMVEAALVPLMMLLERPAGEIE
                     LVTRYADHAGVVFQARDDILDATATSAQLGKDAGADLGKANLVRVYGLPEARRLMEQHR
                     ADAVACLHALPFDTRLLEGIVDHFADRRR"
     misc_feature    12446..12460
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            12656..13651
                     /locus_tag="CS0771_RS38430"
                     /old_locus_tag="CS0771_77490"
     CDS             12656..13651
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.5"
                     /locus_tag="CS0771_RS38430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77490"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_212845515.1"
                     /transl_table=11
                     /translation="MSRILFGVRDAADIRFCISPLWETVRGRYVLGNSDRFPVHLPWLR
                     WARQVRPDPAAADGLALLSELTRAHGYLPDFLTPAPPGPLGELDDELAVVAATPADVLH
                     ADLAATTQKLPLGPRTTALLDDPARLLGELVVGAREWHRVAIAPYWARMRAVLEADVAY
                     RSRQLAEGGVRLLFDSLHPTVGWAGDHIASADPWDIELDLRGRGLPLMPSVFVRSKVLW
                     TLREDSPPFAVYPARAVGSVWEDGPAADGALAALFGASRARLLDMLRQPATTSELARRT
                     GMAAGTVSEHLGVMHAAGLLARSRHGRTVLYVATAAGQSLLDARDRPDPG"
     gene            complement(13665..14729)
                     /locus_tag="CS0771_RS38435"
                     /old_locus_tag="CS0771_77500"
     CDS             complement(13665..14729)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013284633.1"
                     /locus_tag="CS0771_RS38435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77500"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_212845516.1"
                     /transl_table=11
                     /translation="MTVLGKPLELRGVTLPNRIALAPMCQYSARDGLPGDWHLAHLGAR
                     AVGGAGLVIAEATAVLPEGRISPRDTGIWSGAHVDAWRPITAFIAAQGAVPALQLAHAG
                     FKASTYWPFAQERGGVPDTDGGWQPAGPGAEPFIPSYRTPRALDEAGIAAVIDAFAQAA
                     VRAVDAGFQAVEIHAAHGYLLHEFYSPLTNHRTDGWGGDRPARMRLALAVARAVRAAVG
                     PDLPVLARVSATDWTDGGWDVTDTVVLARELAAAGVDLIDCSSGGAAPHADIPLGPGYQ
                     VPLAQRVRAEAGVPTGAVGLITEPEQAERIVEDGQADLVLLGRELLRDPYWPRRALAKL
                     GGLPQWPDQYQRAF"
     gene            complement(14835..14978)
                     /locus_tag="CS0771_RS38440"
                     /old_locus_tag="CS0771_77510"
     CDS             complement(14835..14978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018793962.1"
                     /locus_tag="CS0771_RS38440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77510"
                     /product="GPGG-motif small membrane protein"
                     /protein_id="WP_203740198.1"
                     /transl_table=11
                     /translation="MELLLWILAVVLVVSGIVSLARRQILWGVVLIVVGLLVGPGGVSI
                     FS"
     misc_feature    complement(15017..15037)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(15033..15854)
                     /locus_tag="CS0771_RS38445"
                     /old_locus_tag="CS0771_77520"
     CDS             complement(15033..15854)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014445558.1"
                     /locus_tag="CS0771_RS38445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77520"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_244871281.1"
                     /transl_table=11
                     /translation="MSVQIARETVVSASPTSLTDTTLDATTGEMLLVRLAELDEQDPKH
                     EDVRQEAICAFLPLAERLARRFRHRGVDSDDLVQVATIGLIQAVDRFDPHRGSAFVHFA
                     VPTIVGELKRHFRDRGWSMRVSRRMQELYLDINRVSPELCQTLGRWPSIEDLAEHLQVS
                     AEDVLAGMHCAQAYRINSLNVAVSGEDGDVELGELVGETDNALESVPDVHAVRQFVKEL
                     PEREQRILSLRFDLGLNQAQIAERIGVSQMHVSRLLSRCLAQLRERMLAED"
     misc_feature    15939..15948
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            complement(16060..17019)
                     /locus_tag="CS0771_RS38450"
                     /old_locus_tag="CS0771_77530"
     CDS             complement(16060..17019)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477031.1"
                     /locus_tag="CS0771_RS38450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_77530"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_244871282.1"
                     /transl_table=11
                     /translation="MTTIELKKTPGAAPEPARSRPSWRAWLVIAAALLLAAFLAGHRLV
                     PNRHGVGSVLDSIAPLFGLAVPVLAIAALLVRSGKALLAVLLPAVIWLAMFGGALLPPS
                     GGPVELRVVTQNLYAGNPDPATTVRALAAGGPDLIALQEASGGTIEELAEELSETYPHH
                     AIKSTVGLLSKHPITKVTGVDTGLDWTRALRAVVKAPQGDIAVYVVHLGSARINETETR
                     DHTIDMLAKALRADKAERVLVLGDLNTAATDRAIAPLSELLHDAQADAGWGWGFTWPST
                     LPVMRPDHVLYRGFTATQAGTLRTPGTDHRAVTSGFAF"
ORIGIN
        1 cgtgccgggg ctgcccgggg tgcgcgagca cccgcgtggc gtggacgcgc ccggcgacgt
       61 cgactccggc ccgctgttcc gcgggctcag cgcctcggcc agcgccgtcg cgctcggcga
      121 cgcggtcctg tacggcgacc gcccggccgc cgcggcgctg accggcctgg ccgagggcgc
      181 gggcctggcc gtgcagtggg acggcacccg gcgctacctc ggcggcgcgc tgcccgtcgg
      241 cgacgccttc ctggcctggt ccctggctgc gcgcccgtgg accggcggcg acctcagcgc
      301 cgccaccggc ccgccgtgga cctggcgcct gccctggtac gcgctcttca cctcgctgct
      361 cgcccccgcc tggctgctgg cgctggtcgc ggccggcgtc ccgcccctcg gccgggcggt
      421 gccgacccga gcacggggct gaaggcccgc cgccaggctc acgacccggg cacggcggcg
      481 aagatcagag tttcgtgtcg gaacctctgc tcacagccaa ggttgtgaca cgaaacgctg
      541 atcttcgcca ggtggccgga gccagaacac cagctcagcc gcgcgggacg gggccgcgca
      601 ccgggtcaga gcacgcgggt caggccggtg aggccgggga cggggtgctc gccgaggcgg
      661 gcgccggtgg cggcgtcgaa ccaggcgatg cggccgggca gggcggcgta cacacgcctg
      721 ccgtcggggc tggcggcgag gccggacacg gagccgcccg cggtccaggt ccgccacgcc
      781 gagacgcccg tgcgcggtgt cgtgtggacc gactcgccga ccgcgacgta cagcgcgtcg
      841 aacgtggccg cggcgtacgc cgtacccgcc gcccgcgggc ccttcgcggt ggaccgcacg
      901 gtgagctgcc cggtgtcgat caccgcgtag gtgccgctgg acacgtccag gacgtacagc
      961 tcggaccggt cgggcgcgat cgccagggtg tgcgccgtgc cggggccttc gccgaacggg
     1021 gcgggcaggt ccacgcagaa cgcccactgc tcggtcaggt gcagcgtgtg cacgaacgcg
     1081 tgcacgttcg agcggcggcc cgcgaccagg tcacgggtgt gcgtgtggtc cggctggtgg
     1141 gtgtagagcg tgtagagcac ctgccggtcc ggcgcgtaca cggcgaaccg gccctcgccg
     1201 ctcatctcct cctcggcccc gtccggcacc gccgccttca gccgggtcag caggcgcgac
     1261 gccttgccgg aggccacgtc gaggtggcgc acccggtagc ggtccggcgc cgcgggcggc
     1321 agccagtcca gcacgaacag gccctcgccg cccgcggtga acgcgtcggg caccaggttg
     1381 ccggtcagct ccagccgggc cacctcagcc gtggtcccgg cgaccacgag cggggtgcgc
     1441 gcccgcccgg cgggcacgtg ggtgacgccc gccgaatccg gggcggccag cgccaccagc
     1501 cgcccgtccg ccgaggcgac ccgcggcacc cacgccccgg ccagccgcgg gcccggggta
     1561 cgccgcccgg tccgcagttc gatggtggac agcaccgtgt ccacgccctc ggcccgcgcg
     1621 gcgaagaccg tcgccccgtc cggggcggcc agcccggcgc cgagccgctc gaccccgtcc
     1681 gcccggagca ccgcgagccc ctccgccacc tgcgccagca ccaggtccgg tgcggacgcg
     1741 gccggttccg gaccggccgg gccgcagccg gtcagcaccg ccgcggcacc cgcgccgaac
     1801 agtgccagcg cttcacgtct cgtcgtcatg cacggtcgag tcacgaccca tcgacgcggt
     1861 tccaccccga tccaggggcc aacgcaagac cgtcggctgg cggattgctg accgagcgga
     1921 tggtccgccg ccgctccgcg atgactacgt ttcacgctcg gagcgatgac gggccgcgtg
     1981 gcggcgggtg aggacgacgg gacttccggg tggaagacga tttcgggtac gagggacgcc
     2041 gcaggcgccg gttcacggtg ctggagcggc tgcgcctgct gcccctggtg gccaccacgg
     2101 tgttcaccgg cgcgctcatc ctgctcatcg tgaccaccgt gcggcagccg gcctcctgga
     2161 acgacgcgct gccctggcag gacgcgccca gcccggcccc ggccgccggg gcgcccatcg
     2221 cgccggacgt gccgctggcg cacaccccgg ccccgcagcg cagcggcgtg cgcgcctcgg
     2281 ccgcgcccag caccgggacc gccgcgccca ccgcggcctc gccgggagcg agctcaccgg
     2341 ctccgccgcc gtcgcccact cccccgcccg ccgtgcagcg caccgtgcgc tacgaggccg
     2401 agaacgccgc cggctcgcgg gcgcgtttcg ccaacgacca ccgcaactac agcggcaacg
     2461 gcttcatgga ctacgagaac acctccggca gctacctgca gtggacggtg caggccgatg
     2521 ccgggcaggc cacgctgcgg ctgcgcttcg ccaacgccag cgggcgcaac cggcccatgg
     2581 acatcagcgt caacggcacc gtcgtggccc gcgacgtacg cttcgacgcc acccgcgact
     2641 gggacgactg ggcctcggcc accgtcaccg tcacgctgac cggcggcgcg aacaccatcc
     2701 gggccaccgc cgtcagcggc gacggcggcc cgaacgtcga ctgcctcgac ctcacccagt
     2761 gacgggtcag ggaatcagca gcagcttgcc cgtggtacgc cgcgacgtca ggtcctcgtg
     2821 cgcccgcgcc gcctcggcca gcgggtaacg tccgccgacc gacacgcgca gcgtcccggc
     2881 ggccacccag ccgagcacgt ccgtggcccg ttccagcagt tcctgacggg tgaccacgaa
     2941 gtcgccgagg gtgggccggg tcagcacggc cgagccggcc tgcatcagcc ggatcgggtc
     3001 cacgggcggc accgggccgc tcgcggcgcc gaacagcgcc agcgtgcccc ggcggcgcag
     3061 cgacgccagg ctcgcgtcga acgtggacgc gccgacgccg tcgtacacgg cggccacgcc
     3121 cgcgccgccg gtcagctcgc gcacccggcc ggccaggtcg tccacctggt cgtagcggat
     3181 cacctccgcc gcgcccgcct cccgggccag tttctccttc gcgtccgtgg acaccgtgcc
     3241 gatcacccgc ccgcccaggt gcgggatcag ccggcacagc agcaggccca tgcctcccgc
     3301 ggcggcgtgc acgaggaccg tgtcgccggg ctggatcgcg tacacgtcat gggtgaggaa
     3361 gtgcgcggtc atgccctgca gcagcaccgc cgcggccgtc tcctcggcca gcccgtccgg
     3421 cagcggcacc agccggtcca ccggcaccac cgcctgctcc gcgtacgtgc cgggcagcag
     3481 cgcccaggcg acgcgctcac cggcgcggac ctcggtcacc cccgggccga ccgccagcac
     3541 ccgcccggcc gcctccaccc cgggcacgaa cggcagcggc gtcggatagc ggccgagccg
     3601 gtggtacacg tcgatgaagt tcaccccggc ggcggccacc tcgacgagcg cctggccggg
     3661 acccggggcg ggcggatcga cctccgccgg gatgagcacg tccgggccgc cgtactgcgt
     3721 gatctgaatc gcctgcatgc gcgtcagcct gccccatcgg ccgcgtgtcc gcctgccggg
     3781 cacgcccggc gagggacaat gagagcagca tcgcagcagg gaggggacgc gcatgaccac
     3841 ggcgacgatg accaagacct tgatggtcga gctgcggttc gaggaggacg tggatctcac
     3901 ccgggccacc gcttccatgc ggctgcccaa cgggcggctg ctggtcggcg agggccaggc
     3961 gcgccgcaac ccggtcgacc ggccccgggc ctccatcggc gaggagatgg ccggtgcccg
     4021 cgccctgtcc ggcctggccc accgcctcct ggaagccgcc gccgacgagg tcgaatccaa
     4081 cgtccacggc ggcgaccccg cgatctgacc cgaaggaagg gcaccttctt atcgctttcc
     4141 gtagtagaag ggcaccttct taacctccgc cgctcgcggc tcgccgatcc ccacacggtg
     4201 gccgtggccg tggccgcaag tcgatcacga agttgtggac gcgacacgcc gtcgagcacg
     4261 cccataagtt catgatcgac gcggaagggg gtggggtcag gcggccaggg cgagcgcgag
     4321 ggggaggacg ccgggggcgc ccgcctggat caggtggcgg gcgacgacgg ccatggtcca
     4381 gccggagtcg accaggtcgt ctatgagcag gaccgggccg gtctgctcac gcagttgcgc
     4441 agccaaggcg tcggggatgg tgaaggcgcc gtggagggcc ttgacgcgct gcgcgctgtt
     4501 ggcgcggtgg acgccgggtt gggcggtggt cgtgacggtg ccgaggaagg gcagcctgcc
     4561 cacgcgggag acgtgctgag ccacggcctg gatcaggcgg gggcgggtgg tgctgtcgat
     4621 ggcgacgaca cccgtgggcc gggcgggcca ggggctgtcg ccgtgggacc agtccttgag
     4681 gacttcgatc agcaccgcca gcaggtcctg cggcggagcc tggtccgccg cgccgtcggc
     4741 cagcagggtg cgcagcgtgc cgccccagcc gaggtcggag aggcggccca cggcacgccc
     4801 ggggtgggtc tgctccgcgg gcgggatgcg gccggacagc ggtacgccga cggcgggcag
     4861 ccccgtgggc cacatcttgc gcggttcgat ctcgacgccg gggcggccga ggaaggtctg
     4921 cgcggcgcgc agggcctctg ctgacacgtc cgcggtgaag gccggggcgg tgcagttgtc
     4981 gcagttgccg caggggcccg ccgcggggtc gtcgagggaa cgccggagga actccatgcg
     5041 gcagcccgtg gcggccgcgt agtcgagcat cgcctgctgc tcgtcctgcc gcgcgcgggc
     5101 gatgcgggcg tagcgggccg cgtcgtaggc ccagggcagg ccggtgtgct cccagccgcc
     5161 ccggacgcgg cgcaccgcgc cgtccacgtc gagcaccttg agcatcagct ccagccggtt
     5221 gcggcgcagg tcgacctggg tctccagggc ctgcgtggac agcggccggc ccgcgtccgc
     5281 cagcgcgcgc agcacgccgc gcacctggtc ctccggcggg aaggccagcg aggcgaagta
     5341 gcgccagatg gccgtgtcct cggggccggg cagcagcatc acgtcggcgc tggcgacggc
     5401 acggccggcg cgacccacct gctggtagta cgcgatgggc gaggcggggg cgcccaggtg
     5461 caccacgaag ccgaggtcgg gcttgtcgaa gcccatgccg agggcggagg tggcgaccag
     5521 cgccttgatc ttgttgtcga gcaggtcctg ctcggcggcg cgccggtcgg cgtcctcggc
     5581 ctggccggtg tacgcggcca ccgcgtaccc gcgcgaagcc aggaactggg cggtctcctg
     5641 ggccgcggcc acggtcagcg tgtagacgat ccctgatccc ggcatccggt ccaggtggtc
     5701 ggcgagccag gccagccggt gggcggggct gggcagccgc agcgcggcca ggcgcagcga
     5761 ctcgcggtcc aggcggcccc gcagcaccag ggcgtcgccg agctgttccg cgacgtcggc
     5821 ggtgacgcgc gcgttggcgg tggcggtggt ggccagcacg ggggtgcccg ccggcagctc
     5881 gtccagcatg gtgcgcaggc ggcggtagtc cgggcggaag tcgtgccccc agtccgagac
     5941 gcagtgcgcc tcgtcgacca cgagcaggcc ggtggtcgcg gcgagccggg gcagcacgcc
     6001 gtcgcggaag tcggggttgt tgagccgctc ggggctgatc agcagcacgt cgaccgaccc
     6061 gtcggcgatc tcggcggtga tctgcgccca gtcctccagg ttggccgagt tgatggtgcg
     6121 ggcgtggatg cccgcccgcc cggccgcctc gacctggttg cgcatcagtg ccagcagcgg
     6181 cgacacgatg accgtcgggc cgtggccgcg cccgcgcagc agcgcggtgg ccacgaagta
     6241 caccgcggac ttgccccagc cggtgcgctg cacgcacagc acccgccgcg cgtcggcgac
     6301 cagcgcctcg atcgcccgcc actggtccgc ccgcagcacc gcgtgctctc ccgccaggcg
     6361 gcgcagcacc gcctcggccc gctcccgcaa ctgcgccctg tcctcggcca tcccgcagtt
     6421 gtaccaggcg ggggtgtcag gcccgccggg tgtcagcccg gcgcaccgcg ggtaagcagc
     6481 gggaatgacc aactacggat acacgctcat gtgcgagcag cgcggcccgc gggacctggt
     6541 cgacgacgcg gtacgcgccg aggcggccgg gttcggcttc gcggtgtgct ccgaccacta
     6601 ctacccctgg ctggacgagc aggggcacgc gccgttcgcc tggtcggtgc tgggcgcggc
     6661 ggcccacgtg accgaccgga tcgggctggt ctccttcgtc acctgcccca ccatgcgcta
     6721 tcacccggcc gtggtggcgc agatggcggc gaccgtcggg gtcatgtccg gcgggcggtt
     6781 caccctcggc ctgggcgccg gggagaacct caacgagcac gtggtgggcg cctacccgca
     6841 ggccacccag cggcacgcca tgctggccga ggccctggac atcatcaagc cgctgctggc
     6901 gggtgagacg gtgcaccaca gcggcgagtt ctacgacgtg cccgaggcgc ggctgtggga
     6961 cctgcccgag gagcgggtgc cgatcggggt ggccgtgtcc gggccgtcct cgtgccggct
     7021 ggccgcccgc cacgacgccg ccatgatcgc ggtcgagccg aaagccgagc tgatcgaggc
     7081 gtacgagaag tcgggcggca acggccgtcc ccgctacggc caggtcgcgc tgtgctgggg
     7141 gccggacgcc gacgcgtgcg cgcagacggc gtacgagcag ttccgctggt tcaacctggg
     7201 ctgggcggtg aacgccgagc tgcccggccc gcgcgcgttc gacgcggccg ccgcggcggt
     7261 caccccggag tacgtcgcgt cgaagatccc gtgcggcccg gacgtggacc ggcacgtcgc
     7321 cgcgatccgc gagttcaccg acgcgggctt caccgacgtc gcggtgctgc agatcggcgg
     7381 cgactcgcag ccggagttcc tcgacttcgc acacaaggag ctgctgcccg cgctcaacgg
     7441 cgggtgacga attgcctaca gcccctaacg atcaacgcgg atcgatacta gggtgcagga
     7501 tgtgtcttcc tcggcgctga tgctgctggg cggggtgccg ttcacgctgc tcgcgatcgc
     7561 cttcctgagc ctgctggcca ggatgcaggc cgccgcggac gggcggccgg tccgcctgaa
     7621 cgcggccgcg cgcgagcggc tgtccgccga ggcgcaggaa ctggaggagg tcgccgccga
     7681 ggtgctcgaa gcggcccgca ccgccgtgct gaaggccgag aagaccgccg cggagctggc
     7741 cgccgccgag gccgaacggg acaccgcctg gcaggcccac ctggacgcgg cgggccggct
     7801 ggaggaggcg ggcgaggccc tgcaggccca gcccgcgccg gaggagccgg cggtgtccga
     7861 ggaggcggtg cgcgagatct cccgggccgc gcgggacgcg tacaaacgcg gggatctcac
     7921 catcgagcag ttgcgcgcgg tctggcagca ggtcgacggc tgggaccagg cccgccagga
     7981 gcgctcgcac gagctgtccc ggctgcgcgc cgaggacgcc gaggcctccc ggctctacca
     8041 ggtggccgcc tcccgcgagc gcgcggcgcg gcgggccgcc gaggtggccc gggtctcgtc
     8101 gcacgccctc acccaggagg cggccgacgc ggcatacgag gcccaggccc tgcagacgct
     8161 cctgcgcaag ggccgccgcg cccgctgacg catacccctc gcgcatccgg ggtacccaag
     8221 ggaaatgcgc gattacgacg aagtggtgga gatcgtctac gcctggcagc aggacaccgg
     8281 cgaaggcgtg cccgcccgcg acctctccga cgaagacctg ttccgcgagc tggcggccct
     8341 ctaccgcacc cgcctcgact ccctgcgcca cgcctccgac caggccctca cccgccacac
     8401 caccagaacc gtggaactag agacggacta cgtccgccgc ttccccgacc gcgagatcaa
     8461 ccccgaccgc ctccgctccg gcgctcgcac ccgctcctga ccgcccccca ctccgtcgat
     8521 cttgcgcgca ctgtgggtgc gacacgcaca aaccgcccat atccctaaca cttcacgcaa
     8581 gatcgacgcg atcttgaggg cggccgcggg gtgtggtgtc ggtaaccggg ggtccggggg
     8641 gtggggtggg gcgtgagatt cttggcgggt gagtggtgcg acgttgatgt tggggagaat
     8701 ccctgtcgat ccgccggtgg tgctggcgcc gatggcgggg atcaccaatg tcgcgttccg
     8761 gcagctgtgc cgggagcagg gggccgggat ctacgtctgc gagatgatca ccacggtggc
     8821 gctcgcggtg cggaacccga agaccgagaa gatgatcgag ttcgggccgg acgagcagcc
     8881 gcgcagcatg cagctgtacg gcgtcgatcc ggacatcacg gccaaggcgg tccgccgggt
     8941 ggtggacgag aacctggccg atcacatcga cctcaacttc gggtgcagcg tcaagaagat
     9001 caccagtaag ggtggcggct cggcgatccc gtggaagcgg cggctgttcg ggtcgatcgt
     9061 gaaggcggcg gtggacgctg cggcgcccgc cggcatcccg gtcaccgtga agatgcgcaa
     9121 gggcatcgac gacgagcatc tgacgtacgt cgaggccggg ctgatcgcgc aggaggccgg
     9181 cgcgaagtgg gtggcgctgc acgcgcgcac cgccgcgcag cgctactccg gcgaggccga
     9241 ctgggagtcg atcgcgacgc tcaagcaggc gctcgacgtg ccggtgctcg gcaacggcga
     9301 catctgggag gccgacgacg cgctgcggat ggtggccgag acagggtgcg acggggtcgt
     9361 ggtcgggcgc ggctgcctgg ggcggccgtg gctgttcgcc gatctcgcgg ccgcgttcgc
     9421 gggccgcccc gagcgggtga tgccgagcct gggcgaggtc gcgctcgtca tgcgccgcca
     9481 cgccgagctg ctcacgctgt ggtggggcaa ggagcgcgag gcggtcaccg acttccgcaa
     9541 gcacgtcgcg tggtatctga agggcttccc ggtcgggtcg gagctgcgcc ggtcgatggc
     9601 gatggcgtcg tcgctgatgg agctggacga cctgctcggc aagctggacc acgaggtgcc
     9661 gttcccggag gccaacctgg gccagccgcg gggccgcacg aactcccccg ccaaggtcgt
     9721 gctcccctac ggctggctgg acgaccgcga ctccgaggcc gtccccgagg acgccgaaca
     9781 cgacgactcc ggcggctgac ccggccccgc ggcaccgacg ctcgcgcgtc cccgtggccc
     9841 cgcgcgtccc gggccgtccg cgcggcgcgg tggcccgctc tctcacgcga tgatcgcggc
     9901 ttcgtgtcgg aatgtggggc ctgaccagag gtttcgacac gaagtagcga tcatcgaccg
     9961 ttggccccgt cccggggccg cggccgtcgt ggtggggccg tcagcggcgg cggtcggcga
    10021 agtggtcgac gatgccctcc agcaggcggg tgtcgaacgg gagcgcgtgc aggcaggcga
    10081 ccgcgtcggc gcggtgctgc tccatgagcc gccgcgcctc cggcagcccg tacacccgga
    10141 ccaggttggc cttgcccagg tccgcaccgg cgtccttgcc cagctgagcc gaggtggcgg
    10201 tggcgtcgag gatgtcgtcg cgggcctgga acaccacccc ggcgtggtcg gcgtaccgcg
    10261 tgaccagctc gatctccccc gcggggcgct ccagcagcat catcagcggc accagcgcgg
    10321 cctcgaccat ggtcgaggtc ttcagccggt acatctccag gatgtcctcg ccggtgaccg
    10381 gccgcgcgtc gcgggcgaag cgcaggtcga ggtactgccc ccggcacagc cgctgcggcc
    10441 cgagcacctt gccgacgtac tcgatgacgt cggtgacccg ctgcgccggg tagtgccggt
    10501 cgagccgagc cagcatgccg aacccggagg acagcatcga gatcgcggcg agctgcacgc
    10561 tgccctcgtc gaacacggtg tgcgcggcgg ggcggccccg gcgcagcgcg gcgtcgtcct
    10621 gcgcgggcag gtcgtcgaag atcaggctcg cggtgtggaa cagctcgatc gcgccgagca
    10681 gcggctcgga cagcgtgtcg gcgacgccga gcccctcggc cagcatcagg gtcagcgcgg
    10741 gccgcagccg cttggcggga ccgtccatcg tgtacgccag gatcggggcc agctcgcccg
    10801 cgtcgacccc ggtgtggcac tcgtgcacca gctcgttgat gcgctccagc cggtccagca
    10861 cgaaggtccg cgcgtccacg ctgttcgggt cgcgctcgcc catgatcgcg gcggcctccc
    10921 gcttgagccg caggtcgccc gtggtcaggt gcggcagggc gcggcggggc accgcggcgg
    10981 cggtacgcag gaacgccgcg atctgcgccg tcgccggata ctcgtcgagc agcgccaggg
    11041 tggtgtgcgg gtcgcggcac aggaacgcgg cgagcttgac ggtgccgatg ccgatcagcg
    11101 cgtcccgagc ggccgggtcg ccgccgtaca cctgctcgac cacgtacgcg tcgtacgcga
    11161 acaggtcgta cagcgggtcg gcccgcccac cggcgcgcgc cgccgcgggc agcgtgaacg
    11221 gggtcagccg gcccgcgcgc cggtcctcgt cgcggtcggc gaggtcgtcc ttgaactggc
    11281 tcaggaagat cgtgttgagg caccgggcgt agaagccctc gtcgacctcg cgccggccga
    11341 gcaggttggc gaccacccgg ctcagcccgg ccttgaggaa gatgtccggg tacgccgcgt
    11401 ccaggccgcc ctccggcggc tgctccgcgt cgcggtgctg ggccaggtac atcgactcgg
    11461 cggcctggta gaggtgccgg tgcgtgccga acgggtagac gtccagcgcg acgccgtaca
    11521 gctcgtgcag ctcctcggcc agcggatggt ccgggatctc ggcgcggtcg acggtgccgc
    11581 cggtggacag cccgcgcagg atcagccggt gcagccggtc ccggtcggcc tgcgggatgt
    11641 gcgcgccgcg caggtcctgg aacgagtcgt cgacgatggc gtacgcggcc ccgtaggcgt
    11701 acgcgccggg caggatccgg gtcaggtgcg cgcgggtggc ggcccggccc gcgtcccggg
    11761 tgtcgtacgc cccgatcgcc agcaccccgg ccagcgtgcg gaccaccttg cccatcgcgc
    11821 cggcccgcac cacggtgtcc ggcaggcagc ggtgcagccg gtccagccgc gccagcagcc
    11881 agcgcgtctc gggcaccccg cgcagcccgg gaaagcgcgc ctccagcgcc tcgaccaccc
    11941 cggccgggcc gtgaccacgc tcgatcgcgg cgagcgtgtc ccgcaccgcg cccgcgtgca
    12001 cccgggccag ccgctcggcg cgcgccacgt cggccgggtc ggggatctcg ctcaggttgt
    12061 acacgccgaa gtagttgagc tcgcgtaccg cctgcgcccg ctgctccctg cggcggcgcg
    12121 gcggccacgc ggcgcgttgc agggtggcca ccgtgccgtg ccgggacagg atcgcccgca
    12181 gctgctcggt gtatccgtcc acatgcgccg cgatcacgcc cggcgagccg tcccgccagt
    12241 ggaagtagtg gtccagcgtc tgccgtacgc ccagcccgat ccgctcggga tcgagatcct
    12301 cccgcccgaa cgggaacggc cgccgcacct cggtggcggt ctccaacacg gcccgtcacc
    12361 tcccccgcgc cgctcgagaa ccggcgctga ccccatgatc ccacccccgc gccagccccc
    12421 cgaccagcaa aggaagggca ccttcttatc gctttgcgat gtagaaggtg cccttccttt
    12481 caggatggcg gggctgggcg ctctcccccg tatgtacaag agcgcctggc ccgtgccgct
    12541 tcggcgcgac ctcgcccgcc ccctcgaccg gcgtgttgtc gcctgtggac atcccatcag
    12601 tagggtgagg gcgccaccca gcgattcggc gtacgccgaa agatcggaga gcccggtgag
    12661 ccggatcctg ttcggggtgc gcgacgccgc ggacatccgt ttctgcatct cgccgctgtg
    12721 ggagacggtc cgcggccgct acgtgctggg caactccgac cgcttcccgg tgcacctgcc
    12781 ctggctgcgg tgggcacggc aggtgcgccc ggacccggcg gcggccgacg gcctggcgct
    12841 gctcagcgag ctgacccggg cgcacggcta cctgcccgac ttcctgaccc ccgcgccgcc
    12901 cggcccgctc ggcgagctgg acgacgagct ggccgtggtc gcggcgaccc cggccgacgt
    12961 gctacacgcc gacctggcgg ccaccacgca gaagctgccg ctcggcccgc gcaccacggc
    13021 gctgctggac gacccggccc ggctgctggg cgagctggtg gtgggcgccc gcgagtggca
    13081 ccgcgtggcg atcgcgccgt actgggcgcg gatgcgggcc gtgctggagg ccgacgtcgc
    13141 ctaccgctcg cgccagctcg ccgagggcgg ggtgcggctg ctgttcgaca gcctgcaccc
    13201 gaccgtgggc tgggccggcg accacatcgc ctcggccgac ccgtgggaca tcgagctgga
    13261 cctgcgcggc cgtgggctgc cgctgatgcc cagcgtgttc gtacggtcga aggtgctgtg
    13321 gacgctgcgc gaggactcgc ccccgttcgc cgtctatccg gcgcgcgccg tcggcagcgt
    13381 gtgggaggac ggcccggccg ccgacggggc gctcgccgcg ctgttcggcg cgtcccgggc
    13441 gcggctgctg gacatgctgc gccagcccgc caccaccagc gagctggccc ggcgcaccgg
    13501 catggcggcg ggcaccgtgt cggagcacct gggcgtgatg cacgccgcgg gcctgctggc
    13561 gcgcagccgc cacggccgga ccgtgctcta cgtggcgacc gccgcgggtc agtcgctgct
    13621 ggacgcccgc gaccgccccg acccgggctg acccctccgg tgcgctagaa cgcgcgctgg
    13681 tactggtcgg gccactgcgg caggccgccg agcttggcca gggcacgacg cggccagtac
    13741 gggtcgcgca gcagctcccg cccgagcagc accaggtcgg cctgcccgtc ctcgacgatg
    13801 cgctcggcct gctccggctc ggtgatcagg ccgaccgcac cggtgggcac gcccgcctcg
    13861 gcgcgtaccc gctgcgccag cggcacctga tagccgggcc cgagcgggat gtcggcgtgc
    13921 ggcgcggccc cgccggacga gcagtcgatc aggtcgacac cggccgcggc cagctcacgg
    13981 gccagcacca cggtgtcggt gacgtcccag ccgccgtcgg tccagtcggt cgcggagacc
    14041 cgggcgagca ccggcaggtc cgggcccacc gcggcgcgta cggcccgcgc gacggcgagc
    14101 gccaggcgca tccgggcggg acggtcgccg ccccagccgt cggtgcggtg gttggtcagc
    14161 ggggagtaga actcgtgcag caggtagcca tgcgcggcgt ggatctccac ggcctggaag
    14221 ccggcgtcca cggcccgcac cgcggcctgc gcgaacgcgt cgatcaccgc ggcgatcccg
    14281 gcctcgtcca gcgcccgggg cgtccggtac gacgggatga acggctcggc accgggcccg
    14341 gccggctgcc agccgccgtc ggtgtccggc accccgcccc gctcctgcgc gaacggccag
    14401 tacgtcgacg ccttgaaccc ggcgtgcgcc agctgcagcg ccgggacggc gccctgcgcg
    14461 gcgatgaacg cggtgatcgg gcgccacgcg tccacgtgcg cgccggacca gatgccggtg
    14521 tcgcgcggcg agatgcggcc ctccggcagc accgcggtcg cctcggcgat gaccaggccg
    14581 gccccgccga cggcgcgggc gccgaggtgg gccaggtgcc agtcgccggg cagcccgtcc
    14641 cgggccgagt actggcacat gggtgccagc gcgatgcggt tgggcagcgt gacgccgcgc
    14701 agttcgaggg gcttgccgag taccgtcacg gcgccaatct acggcgcgga tgtgaaatcg
    14761 cccggtgtct gtggtcacac agcaaggggt gggtggaccg cggtccaccc accccagttc
    14821 ttgcggcgcg caccctacga gaagatgctg acgccccccg gtcccacgag cagaccgacg
    14881 acgatgagca cgacgcccca gagaatctgg cgccgagcca gcgagacgat cccggacacg
    14941 accagtacca cggcgaggat ccacagcaga agttccatgg caaccatcta cccgcgacac
    15001 cggacgtgaa accgagaaat cgtcaccccg gctcagtcct cggccagcat gcgctcccgc
    15061 agctgggcga ggcaccggct gagcaggcgg gacacgtgca tctgggagac cccgatgcgc
    15121 tccgcgatct gcgcctggtt caggcccagg tcgaagcgga ggctcaggat gcgctgctcg
    15181 cgctccggca gttccttgac gaactgccgc accgcgtgca cgtccggaac ggactccagt
    15241 gcgttgtcgg tctcgcccac cagctcaccg agctccacat caccgtcttc gccgctgacc
    15301 gcgacgttga gcgagttgat gcggtaggcc tgcgcgcagt gcatcccggc gagcacgtcc
    15361 tccgcgctca cctgcagatg ctcggctagg tcctcgatgc tcggccaccg gccgagggtc
    15421 tggcagagct ccggggacac ccggttgatg tccaggtaga gctcctgcat gcggcgactg
    15481 acccgcatgc tccagccacg gtcgcggaag tggcgcttga gttcgccgac gatcgtcggc
    15541 accgcgaagt gcacgaaggc actgccacgg tgggggtcga aacgatccac ggcctggatc
    15601 aggccgatgg tcgcgacctg cacgaggtcg tcgctgtcca cgccacggtg gcggaagcgg
    15661 cgggccaggc gctcggccag cggcaggaag gcgcagatgg cctcctggcg cacgtcctcg
    15721 tgcttggggt cttgctcgtc gagctcggcg aggcggacca gcagcatttc gccggtcgtc
    15781 gcgtcgagcg tggtgtcggt cagggacgtg ggggacgcgg acacgacggt ctcgcgggcg
    15841 atctggacag acattgcaaa gcctccggcg cagtggaacc gcgggggatc cggcgacggg
    15901 gtctccggac gcggtcctgc tgtgacggac ccggcacccg tttcttgagc gccgtaacgg
    15961 ctgaaagccg gcccggccga agccgagcag agatgacgtt accaagtaag tgcccgaaag
    16021 taccagtccg gacgagagga aagtacacgt acgggtttcc tagaaggcga accccgaggt
    16081 cacggcccgg tggtcggtgc cgggggtgcg cagcgtgccg gcctgcgtgg cggtgaaccc
    16141 gcggtagagc acgtggtccg ggcgcatcac cggcagcgtc gacggccagg tgaagcccca
    16201 gccccagccg gcgtcggcct gcgcatcgtg cagcagctcc gacagcggcg cgatggcccg
    16261 gtcggtggcc gccgtgttca ggtcgcccag caccagcacc cgctcggcct tgtccgcgcg
    16321 cagcgccttg gccagcatgt cgatggtgtg gtcgcgggtc tcggtctcgt tgatccgggc
    16381 cgagccgagg tggaccacgt acaccgcgat gtcgccctgc ggcgccttga ccaccgcgcg
    16441 cagcgcgcgg gtccagtcca ggccggtgtc gaccccggtg accttggtga tcgggtgctt
    16501 gctgagcagg ccgaccgtgg acttgatcgc gtggtgcggg taggtctcgg acagctcctc
    16561 ggccagctcc tcgatggtgc cgccggacgc ctcctgcagc gcgatgaggt ccgggccgcc
    16621 tgcggccagc gcccgcaccg tcgtcgccgg gtcggggttg ccggcgtaca ggttctgggt
    16681 gaccacccgc agctcgaccg gcccgccgga gggcggcagc agcgcaccgc cgaacatcgc
    16741 cagccagatc acggcgggca gcagcaccgc cagcagcgcc ttgccggagc ggaccagcag
    16801 cgccgcgatc gccagcaccg ggaccgccag gccgaacagc ggcgcgatgc tgtccagtac
    16861 gctgcccacg ccgtgccggt tggggaccag gcggtgaccg gcgagaaagg cggccagcag
    16921 cagcgcggcg gcgatgacca gccacgcgcg ccaggacggc cgcgaccggg ccggctcggg
    16981 cgcggctccc ggcgtctttt tcagctcgat ggtggtcact gtccgtatgt taccggggaa
    17041 gacccgaaac taactcgaca atcgtgccag ggcttcgctg agaagtc
//
