LOCUS       NZ_AP023360            23093 bp    DNA     linear   CON 25-AUG-2024
DEFINITION  Catellatospora sp. IY07-71 chromosome.
ACCESSION   NZ_AP023360
VERSION     NZ_AP023360.1
KEYWORDS    RefSeq.
SOURCE      Catellatospora sp. IY07-71
  ORGANISM  Catellatospora sp. IY07-71
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Catellatospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Catellatospora sp. IY07-71
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8595826)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 381x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326265.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 05:22:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,732
            CDSs (total)                      :: 7,655
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 20 of 92
            Pseudo Genes (incomplete)         :: 82 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:09:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7210911
            Orig. end                         :: 7234004
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023360.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..23093
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="24"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23093
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23093
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13093](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13093)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    662..676
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.75"
                     /tool="antismash"
     misc_feature    complement(707..721)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            720..3740
                     /locus_tag="CS0771_RS32165"
                     /old_locus_tag="CS0771_64750"
     CDS             720..3740
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="CS0771_RS32165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64750"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_212844506.1"
                     /transl_table=11
                     /translation="MADGGTLQDLARMLRQLKRRDARRRGGTEVTYRALAARTGWSTGI
                     IAHYFTGKTLPPTDRFDTLVRLLGASPAEQGRLATLRDRVDEDRRQPAAPGVHTVRLLG
                     PVEVSGPRGRATLVGGRQRTLLGLLGLRAGTPVSPARLTEALWGEQPPRTATGSLYSHI
                     ARVRQALEDCGLPGILVTRDAGYLLDLRPADVDVARFHDDAARGRQALARGAAAEAVGH
                     LLDGLGLWRGEAFEDAEPAGWAAAAVRGLAEARMRCLDDLWDARLRLGEHVAAVDEIER
                     LLAADPGRERLVGLLMLALCRSGRHADAVRAYQRLRSHLAEQLDVEPGPELQRLHLAVL
                     RRDAGAGFDRPPSAPRPAQLPPAAGHFTGRGPEEAALDTLLSRPGPIAVISGPGGMGKT
                     ALAVHWARRVIDRYPDGQLFLDLRGHDPATAMPVQEALGQLLRALGVTADPAAGDPGPY
                     RSALHERRMLILLDNAGSAEQVAPLVPPDAGSLLIVTSRHQLPALAVDHEVAAVSLDAL
                     PHAEASLLLRRVLGHDRVDREPEQAGLLVDLCGGLPLALRIAAAKLAARPLRSLAELVG
                     ELTGGNRLDALSVAGHPGGVRAVFAATYQTLSPPAAALFRRMGHHPGPTFTAYLATAVA
                     GRPAAPALDELAAAHLITEVAEGRYRFHDLIRLYALGCAGPDEAAQTRSALFTWYLALA
                     GTANQLLEPARDRVKLSWQDPPPSLPPLPDATRALDLLDDERPSLLPIARLAAAHGDAR
                     ITWQLTYLLASYYTHRGRWSDYAEICREGLAAALRLDDPVGERLMRSGLGVAYNVTHRH
                     EDALHQLTRALELMRAGGDQRGQGMALNNIAHAHAQLGMLPAARDAFEQALDLHTADNH
                     LPGVTLALNNLADIHTQLADFEAAFGALRRALRLSRDIGNAHLEGAVLQNLGETLLADG
                     DEDAALHHFGLALAIRRRIGEKRREADTANAIGLLQLSRGEHASALDHFGRALALSREI
                     DDRRLESATLANMALLG"
     misc_feature    2883..2885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3737..4615)
                     /locus_tag="CS0771_RS32170"
                     /old_locus_tag="CS0771_64760"
     CDS             complement(3737..4615)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0007154 - cell communication [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015140.5"
                     /locus_tag="CS0771_RS32170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64760"
                     /product="Calx-beta domain-containing protein"
                     /protein_id="WP_212844507.1"
                     /transl_table=11
                     /translation="MTMKSRMLPALGAAVTALAAVIAAAAVGDHPGAAADCRRSVAIDP
                     QVTVSEAAGTLTFTVYTASCAAAGSVAYTVTDGAARRPGDYQLAGGVLQWSAGDTGSRQ
                     VRATVAGDGLTEALLEDFTVTLGNASQNVRIVSPVGRGRIFDDDTQVRAATIDHRLCLL
                     EPRTSPPPTTLPSPSPTAKPDPDPGSGTPATPCTIESGNIISSPFGLNTPLTADATVHF
                     RTSDGDLIAGLDYVPVDRTITIPAGATTVLVPIQLLPHAFTQDGKHFTVAISSFSGGQV
                     VSGTARVTVWR"
     misc_feature    complement(4569..4581)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(4729..5091)
                     /locus_tag="CS0771_RS32175"
                     /old_locus_tag="CS0771_64770"
     CDS             complement(4729..5091)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CS0771_RS32175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CS0771_64770"
                     /product="hypothetical protein"
                     /protein_id="WP_212844508.1"
                     /transl_table=11
                     /translation="MTVQSILLRFSYFEHDWITEDIDGPEAGEAVLMRVASEGDWFEVE
                     GAEPEEFDTLDALAEGAERVIAGEWQMPAAAVRLPVDRLRTLIADGGWTFAAGEFSEFV
                     GNHHDTEMLVKLVRDR"
     gene            complement(5105..6202)
                     /gene="mraY"
                     /locus_tag="CS0771_RS32180"
                     /old_locus_tag="CS0771_64780"
     CDS             complement(5105..6202)
                     /EC_number="2.7.8.13"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="mraY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014426.1"
                     /locus_tag="CS0771_RS32180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64780"
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="WP_212844509.1"
                     /sec_met_domain="Glycos_transf_4 (E-value: 5.7e-32,
                     bitscore: 109.7, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISSVVAAAVAFVFALICTPVATRALARLRAGQPIRDVNPAAHQA
                     KRGTPTMGGLIFIVGTVLAYVVGHLVMNALPAAQIVPPGPTMTGFVLLGLMVFCGGIGF
                     VDDFLKVTKKNTAGLSGRWKLALQLMVGTGFGVVALGFPSTAGWSVAGTRLSFVREISW
                     LDVGQVGAVVVFIAIVMASTNAVNLTDGLDGLATGTSIIVLAAYGLISFWQYRHWCADP
                     AMQSAFCYEARDPLETALIAGAAAGALLGFLWWNTSPARIIMGDTGSMALGGLIAGQAV
                     ATRTVLLLPLLAALFVIITMSRIIQYTSYKTTGRRVFRMSPLHHHFELVGWHEVTIVTR
                     FWIIAGAGVAAGLGLFYADFLAHLP"
     misc_feature    6370..6383
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     misc_feature    complement(6480..6497)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.07"
                     /tool="antismash"
     gene            complement(6582..7229)
                     /locus_tag="CS0771_RS32185"
                     /old_locus_tag="CS0771_64790"
     CDS             complement(6582..7229)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022747.5"
                     /locus_tag="CS0771_RS32185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64790"
                     /product="DUF3105 domain-containing protein"
                     /protein_id="WP_212844510.1"
                     /transl_table=11
                     /translation="MAEPRMSRTAVAAAAVGLGLLAAAAVPFVRAYADSPRHRPAASFG
                     VAADQAGCDAELTDPVSGVGMHVGPGTSQPTATRVGYETVPPSSGPHYVYPAQRARRFY
                     LPQDRPAMEELVHNLEHGYTVVWYTGTLPAAEVEALRELAVKLGDDAYGEKFIVSAWDD
                     SYGAFPAGRPLAMSHWGRTAGYRQFCARVSGAAIERFVLAHPAADAPEVDGM"
     gene            complement(7222..7797)
                     /locus_tag="CS0771_RS32190"
                     /old_locus_tag="CS0771_64800"
     CDS             complement(7222..7797)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014494.5"
                     /locus_tag="CS0771_RS32190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64800"
                     /product="flavoprotein"
                     /protein_id="WP_212844511.1"
                     /sec_met_domain="Flavoprotein (E-value: 4.6e-29, bitscore:
                     99.7, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAHPVTPFQRVLVAACGSSDVVTLPQSILAMRFALGLQVRVVL
                     SAAAASFVTAKAFTAVTGEPAYDDGVGEAPGVAHLDLARWADLVLVMPATANTIGKAAH
                     GIADSLLTTCVLAAAAPVVFVPSMNAAMWDRPAVQRNIEQLRADGHGIVPPVGVLALST
                     GTVTGRGAPPIGEVLQWAATFVAERRDG"
     gene            complement(7776..10004)
                     /locus_tag="CS0771_RS32195"
                     /old_locus_tag="CS0771_64810"
     CDS             complement(7776..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="CS0771_RS32195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64810"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_212844512.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.9e-29, bitscore:
                     101.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRLLASWWRRIRGVPVVLQMAEADCGAACLTMVLRRHGLPATLS
                     GVRDDIGVGRDGVSAWAVIDAATRHGLTAKAYRATPQAVTQVPLPAIAHWEHDHFVVVE
                     RVGRRGARIVDPALGRRLITPDDLATSLGATVIALTPGEPASAPSRPVRIPVRQRLRRA
                     RAAVGRFLPALGAVFAVSLLLQLLGLALPLATTVAFDEIMPARETSLMPYLAIGIGALV
                     LTQFAVAHLRSMMLVNLQTRVDRELMTRLFGHLLRLPYAFFQQRSSGDLMQRLSSSILL
                     RELVTAQVLTAVIDGGLVTVYFAVLATRDSEFALLAGGIGLAQVLAVAVVNSRLIRLSH
                     RQLNVQAEAESALMEALSGIATVKSMGVERQVYDGWLTRYDAALRVDRAQNRLSSTVGN
                     VTAAVGLAGPLALLWLGTARMFEGGMSLGEMLGLQALAMSFLVPLSSLVSSAQVLQSVV
                     SHLQRLRDVFAARPETGDGEALETPRLRGAIQVRGVGFRYDAQSPYVLRDVSFDILPGQ
                     KIAVVGASGCGKSTLAMLLTGLYRPTEGEISFDGVPQARIAPQALRRQFGVVLQESYLF
                     RDSIRRNVALADPSATAERIRAAAAIAGIDADIDAMPMGYDTRVAERGQALSGGQRQRL
                     SIARAVVGDPAVLLLDEATSHLDVATERRVDQAISALRCTRVVIAHRLSTVRNADKIIV
                     LADGRIAEQGSHDELLAARGVYAELVASQLDDSTTPAEGEQPCLQPTR"
     gene            complement(10001..13093)
                     /locus_tag="CS0771_RS32200"
                     /old_locus_tag="CS0771_64820"
     CDS             complement(10001..13093)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CS0771_RS32200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64820"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_212844513.1"
                     /sec_met_domain="DUF4135 (E-value: 1.7e-75, bitscore:
                     253.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.2e-45, bitscore:
                     151.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALHAALNLRERLALPAPGTGGAASDRARWRLTRWRELDAFTGTA
                     LWTERLAADRLDEPALLRLLDDTPDDLRHRAGGDPGWITALRRRYAGPGADLPIEAATD
                     RPMAAAAVVAAPLVAHATRQVTEHARRLAAATPGAPFDPDTVAAATVPGLLDELVVQLS
                     RAAVLELNIARLHEQQAPAGPAERFHTFFARLREPAAALAFLTAYPVLARQVLGTADRW
                     AARTCELLDRLAADAALLRHTFTGGAPLGVLTAADETGDPHHGGRRVLLARFSGGVTIV
                     YKPRDVTVEARYADLVDWLNERGADLRACAVVPRAGYGWAEFVPADTSTGDAAAYARRR
                     GGLLALLYALGATDFHDENLVTHGGHPVPIDLETLFTPAVTERRSAVADSVLGVGALPT
                     GDAVAAGRACGCTRWVGVGTDLMRLELAPAHSHAVAGPGVDLAAYTEDVVHGFRVTYAL
                     LRAARGVLAADDGPLAAFAADEIRVVLRPTRTYRRLAEAALHTDHLRDGLDRDRLLDWL
                     WSGVAQLPPLRDFVAAERSDLDAGDVPRFTARAGATSLGTGTGDPVPDVLVRSGLAEAR
                     RRLRGLGDTDLARQVWLIRAAYAAQADGAGAPHAAVRWQLPDLAVQLGEPAREDTPESA
                     LPKVRRRALDAAAAIGDRIVELSDHDGWFALTPAGIGWRVGRAADHLYDGTAGIALFLA
                     WLGAQTGEGRFADAADRAAGRLATRIAQRAVAGTSIGAFTGWSGLSYCYGHLAALGHRS
                     AHTTADLIITRLDALVGTGTVLDVVDGAAGCVLALLSAGHDTDRVLPLASRAADLLLQP
                     PPGGPRLGGFSHGTAGQAAALAAMWHATGQQRYLDGALAALQHDRSLFDPARGNWADLR
                     EPGRFSLTWCHGAPGVGLSRLRIRAALGIHPDSAPSVPAGTPDGEHDRLTAEIATAVRT
                     TLAGGFGRNHSLCHGDLGNLDLLLAAGEPDRTVAAVAAAILDDGRTYGWRAANPTGHPS
                     PELMTGLSGVGYGLLRLAAPETVPALLMLAPPAPTTTWSKP"
     gene            complement(13203..13385)
                     /locus_tag="CS0771_RS32205"
                     /old_locus_tag="CS0771_64830"
     CDS             complement(13203..13385)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="CS0771_RS32205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64830"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_212844514.1"
                     /transl_table=11
                     /translation="MSISDVVRNWTDEFHRATSPELSQAAHPAGLVEMSRDELQTVAGG
                     AAIDGHTSMCCHCVC"
     CDS_motif       complement(13251..13385)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSISDVVRNWTDEFHRATSPELSQAAHPAGLVEMSRDELQTVAGG"
                     /locus_tag="CS0771_RS32205_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13203..13250)
                     /prepeptide="core"
                     /locus_tag="CS0771_RS32205_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.80"
                     /molecular_weight="1468.8"
                     /monoisotopic_mass="1467.6"
                     /core_sequence="AAIDGHTSMCCHCVC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSISDVVRNWTDEFHRATSPELSQAAHPAGLVEMSRDELQT
                     VAGG"
                     /leader_location="[13250:13385](-)"
     gene            13757..16396
                     /locus_tag="CS0771_RS32210"
                     /old_locus_tag="CS0771_64840"
     CDS             13757..16396
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="CS0771_RS32210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64840"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_212844515.1"
                     /transl_table=11
                     /translation="MPDGPTHLARLDRPWPFTGRQAERAAIARTLAGGRGVLITGDPGS
                     GKSRLLDEVLTGADDGSRLVLRATATYGWHEVPFGAFGHLVAEPAAHPTDLLTEAMRRV
                     DALAQGRSVLVGVDDLNWLDDTSTALLQRMSTETGLRVVATVRTGDLGRSPVAALRRHS
                     RLDRLDLAPFSQDGFADLITAALGDPADGLTRNALWHLTQGNPLLLRETLRCGLDSGEL
                     ARHHGIWTWPVDEAHHPHRCDMIAETGGTLTAAELQALQYIARAGAAPLTALDRLLDPA
                     AAESLEERGIIHLVGTGRDASLAIAHPLYAEVAQAHTGALRERRMLRELADALAQTSTG
                     TAEDAVHVTAWRCEAGDPVPAADAVAAAQWFLARGDAARAARIAARADGPHAAWQLGRA
                     LVAQDRVEAAQTHLTTAYEQLTDPHERAEAAALLVLNTFLGLRQVDTARDLLATAAAAL
                     PPDARPGLLAAEAALAVLTGSAAAAASTVAALDEHPPRDLVLRMAVAPLRPYLLIAAGQ
                     PARAAAMFDSGQAAPPAVWPVMRAAAQTCHVQALLLAGQAPRAAELAAGYYRDALTRGA
                     PDAVALLAMIIGKCAYHGGRLADARRWLREARSLIDPHTLFPISENVLSTYAWTAAQQG
                     DLDDARSALDQLAAALPPHGAPAKEAALAQAWLAVSAGQRDTAVRTLREQLQASLSRGM
                     LTLAAERLHLLARLDPDVDTARRLREIAHQCDSPLFGLWAELADGLARRDPIVLDHVAT
                     AFEERGHLRLAMEALAPAATAYQRRGDLRRANAVTHRIQLVREQCEGWWPQWHPAAPPV
                     ASALTAREQEVCELAASGLDNAAIAARLVLSVRTVENHLQRAYHKLGVAGRTRLRLALM
                     PETAPSGR"
     gene            complement(16410..16592)
                     /locus_tag="CS0771_RS32215"
                     /old_locus_tag="CS0771_64850"
     CDS             complement(16410..16592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287071.1"
                     /locus_tag="CS0771_RS32215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64850"
                     /product="hypothetical protein"
                     /protein_id="WP_212844516.1"
                     /transl_table=11
                     /translation="MSQPELDPEQYPPIDPSAPIPDDPRELSPDAPDVLPEAPVEPEPG
                     EGDTGGDPGGVREPA"
     gene            complement(16651..17151)
                     /locus_tag="CS0771_RS32220"
                     /old_locus_tag="CS0771_64860"
     CDS             complement(16651..17151)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CS0771_RS32220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CS0771_64860"
                     /product="hypothetical protein"
                     /protein_id="WP_212844517.1"
                     /transl_table=11
                     /translation="MTRVVARPRIRIVLLFIVSDVFVLLGLSYLKNGHVIAERDWLGVA
                     LACALTLVGLLGIWRALRQGVVIDQDGLLVRSFSRPDRTLTWDHVSSIDCGQVFLRGGR
                     PLYAPILQIDGVGRLPVSELGSHSLEEAEQRAADLRSLQAARTPATADRPVPVAPAEQG
                     SPV"
     misc_feature    complement(17213..17228)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            complement(17264..17692)
                     /locus_tag="CS0771_RS32225"
                     /old_locus_tag="CS0771_64870"
     CDS             complement(17264..17692)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018585300.1"
                     /locus_tag="CS0771_RS32225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64870"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_212844518.1"
                     /transl_table=11
                     /translation="MSDWNTKVIEEFRANEGRVGGPFTGAPLVLVHHRGRKSGRELVSP
                     MMYLPHETDEDVVYVFASKAGAPHNPDWYYNLTAAGRGAVERGTETYSVSVRELTGSER
                     DRRYDEQAGLYPGFAEYAQKTAGIRTIPVLELTRVPAV"
     CDS             17748..17945
                     /gene="allorf_7228659_7228856"
                     /locus_tag="allorf_7228659_7228856"
                     /protein_id="allorf_7228659_7228856"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MADAASGLEQGAPAALKTEVIAAGAGGTRRRGGGATATTAGCGRA
                     GRMTRFEQPSHRVRSIRPPY"
     CDS_motif       17748..17819
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MADAASGLEQGAPAALKTEVIAAG"
                     /locus_tag="allorf_7228659_7228856_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17820..17945
                     /prepeptide="core"
                     /locus_tag="allorf_7228659_7228856_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="4185.7"
                     /monoisotopic_mass="4183.2"
                     /core_sequence="AGGTRRRGGGATATTAGCGRAGRMTRFEQPSHRVRSIRPPY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MADAASGLEQGAPAALKTEVIAAG"
                     /leader_location="[17747:17819](+)"
                     /alternative_weights="4203.7"
                     /alternative_weights="4221.8"
                     /alternative_weights="4239.8"
                     /alternative_weights="4257.8"
                     /alternative_weights="4275.8"
                     /alternative_weights="4293.8"
     misc_feature    complement(17794..17808)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    complement(17898..17916)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.37"
                     /tool="antismash"
     gene            17955..18593
                     /locus_tag="CS0771_RS32230"
                     /old_locus_tag="CS0771_64880"
     CDS             17955..18593
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018731540.1"
                     /locus_tag="CS0771_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64880"
                     /product="carbonic anhydrase"
                     /protein_id="WP_305835463.1"
                     /transl_table=11
                     /translation="MAEIQTPSPEEAFELLLAGNHRFVAGVPEHPNQDATRRAEIAPGQ
                     RPFAVVFGCSDSRLAAEIIFDRGLGDLFVVRTAGHVMGAEVLGSIEYGVDVLDSPLVLV
                     LGHDSCGAVAAACAALEGGMAPSGYVRDVVERVTPSVLAARAAGRVEPDEILAEHVRHT
                     VDLLLDRSRVLAERVEDGRAAVVGLCYRLADGSAQVVAARGLDAATARR"
     CDS             complement(18612..18716)
                     /gene="allorf_7229523_7229627"
                     /locus_tag="allorf_7229523_7229627"
                     /protein_id="allorf_7229523_7229627"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRGPVPGRGTSAAAPIGLSAWRGQGCAAGARVPP"
     CDS_motif       complement(18675..18716)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRGPVPGRGTSAAA"
                     /locus_tag="allorf_7229523_7229627_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18612..18674)
                     /prepeptide="core"
                     /locus_tag="allorf_7229523_7229627_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.90"
                     /molecular_weight="1900.2"
                     /monoisotopic_mass="1899.0"
                     /core_sequence="PIGLSAWRGQGCAAGARVPP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRGPVPGRGTSAAA"
                     /leader_location="[18674:18716](-)"
     gene            18821..19783
                     /locus_tag="CS0771_RS32235"
                     /old_locus_tag="CS0771_64890"
     CDS             18821..19783
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="CS0771_RS32235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64890"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_212844519.1"
                     /sec_met_domain="APH (E-value: 1.7e-09, bitscore: 36.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRADEWAKAQDWIAETLAEQGIAATGPAVVDRVRPWSTTARVPVA
                     GGQAWFKYNNAGSRYEAALMRLLAAIAPHDMLVPLAVDAELGWMLLPDGGPTMREITSD
                     TFDRDRWEHLLRRYAELQRAAAPHAAGMLAAGVPDFRPHTVAAQYEKLLTDPYVLANLD
                     AGKMAGLHEWVPRIERMCRRLAAGGIAPSVQHDDLHPSNVFADGDGGLRFFDFGDATVA
                     HPFGSMLVVLRVVHRDAKVEHKDPLLYELRDRYLSAWTADGRDLAELRELCQDAIVVAK
                     IGKALSYQRSLQDATEEALAEYGEGIYGWLEELLGPDVI"
     gene            complement(19809..21758)
                     /locus_tag="CS0771_RS32240"
                     /old_locus_tag="CS0771_64900"
     CDS             complement(19809..21758)
                     /GO_function="GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012862.5"
                     /locus_tag="CS0771_RS32240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_64900"
                     /product="caspase family protein"
                     /protein_id="WP_212844520.1"
                     /transl_table=11
                     /translation="MPKVHALLVGIDRYKLPELDLQGCVNDVDLAEALLRDRVAPGDLV
                     VERLLDEQATRAGIIEAFRRHLGGLGPGDIALFWYSGHGSTAPLPEEIWYAESAGMCQT
                     VVCHDSRADVADLYDKELGILAHEVVTTGAQLVTIMDSCHSRSGMRDVPVPGTKARLAP
                     ASTTAPALRDLLPELVAAAADPKRAAPGLQLPGHVALAACNEWERAREWPFADGWHGVF
                     TEALGHALARLGPHATYRQVFSHARCRVEGWRSSQVPTLEALGDLADLEFLGGTLRPRA
                     SRISMRHLHGRWELDAGAMHGVVADARFGVHHAAPLQQVRVLSVHVRHSVVEPVGWAPD
                     EEKHYEMVLTDVPLPPVAVSIEADPDVTARLTGTVQVSGPGGGPSPHVRLVRPADPFTS
                     GLRLRVRQDHARGTVQIFGLDDRSLADPVGADDGGIEQTVRRLEHIARWLQIRNLPSAS
                     PALAEAIQIELVPAPADGSRPARGHEPPPVNDLVLDYTWNGTSWVPPTVFIRLRNTTDR
                     RLFCVLLDLTDRYRMHANLFPGEYVEGGWTAEAGHGGAVAFRLPPDRPVEKGAFVTDWL
                     VLLVAEEPFSSAPFSLPRLGERSRSVSRDTLPGINGVLDRLGMRAVQRDVELMPPPTAL
                     DWAVKVVEVTTRVP"
     misc_feature    22605..22619
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.26"
                     /tool="antismash"
ORIGIN
        1 ttgttccagc gggcgccgcc ccagtacggc gagatgtcgg cctggcggtt gaacagcagg
       61 tccggggcgc gttcgacggt gacggccagc ggcaggcggg cctcggccag gatcgcctcg
      121 cggtcggcgt cggtgctcac cgtgacggcc aggccggagc cgtcgacctg cggggcggcg
      181 gtgccgaccc ggctgtcggc gccgagccgg tccacctcgg cggcgagttc ggcctcgctg
      241 tagcgggcgg gcaggaactt gacgggtacg ccggtgcggg cggcgcgttc gcgggcgtcg
      301 gcggggacct cgcccttcca gtagacgtgc agctcgccgt tctcgggggc ggcgatcgtg
      361 ccggcgtagc cgggtgagtc caccgacagg atgtcgtcgg cggcggtgtt gaggcgggtc
      421 tgcgcctcgc tgaggtcctc ccaggtgcgg aagccgccgg ggacggcttc ggcgggggcg
      481 gcgccgggct gttcggtctt gggctcctcg gcggccgagg cgcccgtggg gggcaggagc
      541 acggccatga ccaggagcgc cgcgacgctc cagccggtcc tggcacggcg ggacggtgtg
      601 tgagtcatgg cagccatcgt cggagcggac ccgtggcggc cggggcgatc ctgaacatcg
      661 ttgaacatcg ctgtctcgca cgtacgatgg acatgcggct tcgtccatcg aggaggctca
      721 tggccgacgg gggcaccctg caggacctcg cccggatgct gcgccagctc aaacggcgcg
      781 acgcccggcg gcggggcggc accgaggtga cctaccgtgc gctggccgcc cggaccggct
      841 ggtcgaccgg gatcatcgcg cactacttca ccggcaagac cctgccgccg acggaccgct
      901 tcgacaccct cgtccggctg ctgggcgcct cccccgccga gcagggcagg ctcgcgaccc
      961 tccgcgaccg cgtcgacgag gaccggcggc agccggccgc gccgggcgtc cacacggtcc
     1021 gcctgctcgg cccggtcgag gtgagcggcc cgcgcggccg cgccacgctg gtcggcgggc
     1081 ggcagcgcac cctgctcgga ctgctcggcc tgcgcgccgg cactccggtg tcacccgccc
     1141 ggctcaccga ggccctgtgg ggcgagcagc cgccccgcac cgccaccggt tcgctgtact
     1201 cccacatcgc ccgggtgcgc caggcccttg aggactgcgg cctgcccggg atcctggtca
     1261 cccgcgacgc cgggtacctg ctggacctgc gccccgccga cgtcgacgtg gcccgcttcc
     1321 acgacgacgc cgcccggggc aggcaggccc tggcgcgcgg cgccgccgcg gaggcggtcg
     1381 ggcacctgct cgacgggctc gggctctggc gcggcgaggc cttcgaggac gccgaacccg
     1441 ccggctgggc cgccgcggcg gtacgcgggc tggccgaggc acggatgcgc tgcctggacg
     1501 acctctggga cgcccgcctg cgcctgggcg agcacgtggc cgccgtcgac gagatcgagc
     1561 ggctgctggc cgccgacccg ggtcgcgagc gcctggtcgg gctgctcatg ctcgccctgt
     1621 gccggtcggg tcggcacgcc gacgcggtcc gggcatacca gcggctgcgc agccacctgg
     1681 ccgagcagct cgatgtggag cccgggccgg aactgcagcg cctgcacctg gcggtgctgc
     1741 gccgcgacgc cggcgccggc ttcgaccgcc cgcccagcgc ccccagaccg gcccagctgc
     1801 caccggcggc cgggcacttc accggccgcg gacccgagga ggccgcgctg gacacgctgc
     1861 tgtcgcggcc ggggccgatc gcggtgatct ccgggcctgg cggcatgggc aagaccgcgc
     1921 tggcggtgca ctgggcgcgg cgggtcatcg accgctaccc ggacgggcag ctcttcctcg
     1981 acctgcgcgg ccatgatccg gccacggcga tgcccgtcca ggaggccctg ggccagctgc
     2041 tgcgggcgct gggtgtcacc gccgacccgg ccgcgggcga tcccggcccg taccgctcag
     2101 ccctgcacga gcgccggatg ctgatcctgc tcgacaacgc gggttcggcc gagcaggtgg
     2161 cgccgctggt gccgccggac gcgggcagcc tgctgatcgt caccagccgt caccagctgc
     2221 cggcgctcgc cgtcgaccac gaggtggccg cggtcagcct ggacgccctg ccgcacgccg
     2281 aggcgtcgct gctgctgcgc cgggtgctcg gccacgaccg ggtcgaccgg gagcccgagc
     2341 aggccggcct gctggtggac ctctgcggcg ggcttcccct ggcgctgcgt atcgccgccg
     2401 cgaagctcgc cgcccggccc ctgcgcagcc tcgccgagct ggtcggcgag ctgaccggcg
     2461 ggaaccgtct cgacgcgctg tcggtggcgg gccaccccgg cggggtccgg gccgtgttcg
     2521 ccgcgaccta ccagacgctg agcccgcccg ccgcggcgct gttccggcgg atgggccacc
     2581 atcccggccc gaccttcacc gcctacctgg ccacggccgt ggccgggcgg cccgccgcgc
     2641 ccgcgctcga cgaactcgcg gccgcgcacc tgatcaccga ggtcgccgag ggccgatacc
     2701 gcttccacga cctgatccgc ctgtacgcgc tcggctgcgc cggccccgac gaggccgcgc
     2761 agacccgcag cgcgctgttc acctggtatc tggcgctggc cgggaccgcc aaccagctgc
     2821 tggagcccgc ccgcgaccgg gtgaagctgt cctggcagga cccgccgccg agcctgcccc
     2881 cgttaccgga cgccacccgg gcgctggacc tgctggacga cgaacggccc agcctgctgc
     2941 cgatcgcccg gctggccgcg gcccacggcg acgcccggat cacttggcag ctgacctacc
     3001 tgctggccag ctactacacc caccgcggcc gctggtcgga ctacgccgag atctgccgcg
     3061 agggcctggc cgccgcgctg cgcctggacg acccggtcgg cgagcggctc atgcgcagcg
     3121 gcctgggcgt cgcctacaac gtcacccacc gccacgaaga cgccctgcac cagctcaccc
     3181 gcgcgctgga gctgatgcgg gcgggtggcg accagcgcgg gcagggcatg gcgctgaaca
     3241 acatcgcgca cgcccacgct cagctcggca tgctccccgc ggcccgcgac gcgttcgagc
     3301 aggcactcga cctgcacacc gccgacaacc acctgcccgg tgtcaccctg gcgctgaaca
     3361 acctcgcgga catccacacc cagctcgccg acttcgaggc ggccttcggc gcgctgcggc
     3421 gggcgctgcg cctgtcgcgc gacatcggca acgcccacct ggaaggcgcc gtgctgcaga
     3481 acctcggcga gacgctgctc gccgacggcg acgaggacgc ggccctgcat cacttcgggc
     3541 tggccctggc gatccggcgg cgcatcggcg agaagcgccg ggaggccgac accgccaacg
     3601 ccatcggcct gctccagctg tcgcgcggcg agcacgcgag cgccctggac cacttcggca
     3661 gggcgctcgc gctgtcccgc gagatcgacg accggcgcct ggagtcggcg acgctggcga
     3721 acatggcgct gctgggctag cgccagacgg tcacccgtgc ggtgccggag acgacctggc
     3781 cgccggagaa ggacgagatg gcgacggtga agtgcttgcc gtcctgagtg aacgcgtgcg
     3841 gcaggagctg gatcgggacg aggacggtgg tggctcccgc cgggatggtg atggtgcggt
     3901 ccacgggcac gtagtccagc ccggcgatca ggtcgccgtc ggacgtccgg aagtgcaccg
     3961 tcgcgtcggc ggtcagcggc gtgttgaggc cgaacggcga gctgatgatg ttgcctgact
     4021 cgatggtgca gggtgttgcg ggcgtgcccg agcccggatc cgggtcgggt ttggccgtcg
     4081 gcgacggtga cggcaaggtg gtgggcggcg gagaggtgcg cggctccagc aggcacagcc
     4141 ggtggtcgat ggtcgccgcc cggacctggg tgtcgtcgtc gaagatccgg ccgcggccga
     4201 ccgggctcac gatccggacg ttctggctgg cgttgccgag ggtgaccgtg aagtcctcaa
     4261 gcagcgcctc ggtcagcccg tcgccggcga cggtggcccg gacctgcctg ctgccggtgt
     4321 cccccgccga ccactggagc acgccgccgg ccagctggta atcgccgggc cggcgggcgg
     4381 cgccgtcggt gacggtgtac gccaccgatc ccgccgcggc gcaggacgcc gtgtacacgg
     4441 tgaaggtcag cgtgcccgcc gcctcggaca cggtgacctg cgggtcgatg gcgaccgacc
     4501 gccggcagtc ggcggccgcg cccgggtggt ctccgacggc ggccgcggcg atgacggcgg
     4561 ccagggccgt gacagcggcg ccgagtgcgg gcagcatcct cgatttcatc gtcatcgccg
     4621 aatcatcggg caccgagctt gtggagagct tgtggaacgc gtgccaagtt gatccacggg
     4681 tttgaatgaa tgggctcgat ccaccgcact gcgcgcgaac ccgcgccgtc agcggtcgcg
     4741 gacgagcttg acgagcatct cggtgtcgtg gtggttgccg acgaactccg agaactcgcc
     4801 cgccgcgaag gtccagcccc cgtcggcgat gagcgtgcgg agcctgtcca ccggcaggcg
     4861 gacggcggcc gcgggcatct gccactctcc ggcgatgacc cgctcggccc cttcggcgag
     4921 ggcgtcgagg gtgtcgaact cctccggctc ggcgccctcg acctcgaacc agtcgccttc
     4981 ggacgccacc cgcatcagga ccgcctcgcc cgcctccggt ccgtcgatgt cctccgtgat
     5041 ccagtcgtgc tcgaagtagg agaagcggag gaggatgctc tgcacggtca tcggcgcatc
     5101 ttagtcaggg caggtgagcg aggaaatcgg cgtagaacaa gcccagcccg gcggccacgc
     5161 ccgcgcccgc gatgatccag aaccgggtca cgatcgtgac ctcgtgccac cccaccagct
     5221 cgaagtggtg atgcagcggc gacatccgga acacccgcct gccggtcgtc ttgtaggacg
     5281 tgtactggat gatccgcgac atcgtgatga tcacgaacag cgcggccagg agcggcagca
     5341 gcagcacggt ccgcgtggcg accgcctgcc cggcgatgag cccgccgagc gccatggaac
     5401 cggtgtcgcc catgatgatc cgcgccggtg acgtgttcca ccacaggaag ccgagcagcg
     5461 ccccggcggc ggcgccggcg atcagcgccg tctccagcgg atcccgggcc tcgtagcaga
     5521 acgccgactg catcgccgga tcggcgcacc agtgccggta ctgccagaac gagatcagcc
     5581 cgtacgcggc gagcacgatg atcgacgtgc cggtggccag gccgtcgagc ccgtcggtca
     5641 ggttgacggc gttcgtgctc gccatgacga tcgcgatgaa gacgaccacg gcaccgacct
     5701 ggccgacgtc cagccagctg atctcccgga cgaacgacag ccgggtgccg gccaccgacc
     5761 atccggccgt gctcggaaag ccgagcgcca ccacgccgaa tcccgtgccg accatgagct
     5821 gcagcgccag tttccagcgc ccgctcagcc cggccgtgtt cttcttggtg accttcagga
     5881 agtcgtcgac gaacccgatg ccgccgcaga acaccatcag gccgagcagg acgaacccgg
     5941 tcatcgtcgg acccggtggg acgatctgcg ccgccggcag cgcgttcatc accaggtggc
     6001 cgacgacgta ggcgagcacg gtgccgacga tgaagatcag cccgcccatg gtgggtgtgc
     6061 cgcgtttggc ctgatgcgcg gcggggttga cgtcgcggat cggctgaccg gcgcgcagcc
     6121 gggccagggc gcgggtcgcc accggcgtac agatcagagc gaatacgaag gcgacggcgg
     6181 cagcgacgac cgaggagatc atggcggtgt acctcctggt gagggagcgg gcaagatcgt
     6241 tgagccgcac agtgtagggg gcgcacggtc gcctgcgccg gacgtcggca gccgcacgaa
     6301 gcggccgaat gtccgatcac tcctcatcgc tcgccgaggg acggggggcc gcgaaccccg
     6361 cccggtaacg gcattcagct tgcgaacgcg caggtcgtgg ctgtcggccg ctcgcgcgcg
     6421 gacgggcaga tcatccccgg cggccacgtc gcaggatcag gcgggaatgc cgcgacatct
     6481 tcacaagacc gccacatctg gcatccccgc gacaatgcgc aacaggatcc ggcagaacgt
     6541 gcgaccgcga cggcgcgggt cggcctgcac gacggaaccc gtcacatgcc gtccacctcg
     6601 ggggcgtcgg cggcggggtg cgcgagcacg aaccgttcga tcgccgcgcc gctgacgcgg
     6661 gcgcagaact gccggtagcc ggccgtgcgg ccccagtggg acatggccag gggccgcccg
     6721 gccgggaagg cgccgtagct gtcgtcccag gccgagacga tgaacttctc gccgtacgcg
     6781 tcgtcgccga gcttgaccgc gagttcccgc agggcctcga cctcggcggc gggcagcgtg
     6841 ccggtgtacc acacgacggt gtagccgtgt tcgaggttgt gcaccagctc ctccatcgcg
     6901 ggccggtcct gcggcaggta gaagcgccgg gcccgctggg cggggtagac gtagtgcggc
     6961 ccggacgagg gtggcacggt ctcgtagccc acgcgggtgg cggtcggctg ggaggtgccg
     7021 ggtccgacgt gcatgccgac accggagacc gggtcggtca gctccgcgtc gcagccggcc
     7081 tggtcggcgg cgaccccgaa cgaggcggcg ggccggtgcc gcggcgagtc ggcgtacgcc
     7141 cgcacgaacg gcaccgccgc ggcggccagc aggcccagcc cgaccgcggc cgccgcgacg
     7201 gcggtgcggg acatccgcgg ctcagccatc gcggcgctcc gccacgaacg tcgcggccca
     7261 ctgcagcacc tcgccgatcg gcggcgcgcc gcggccggtg accgtgcccg tgctcagcgc
     7321 cagcaccccg accggcggca cgatgccgtg cccgtcggcg cgcaactgct cgatgttgcg
     7381 ctgcacggcc gggcggtccc acatcgccgc gttcatggac ggcacgaaca ccacgggtgc
     7441 ggcggcggcg aggacgcagg tggtgagcag gctgtcggcg atgccgtggg cggccttgcc
     7501 gatggtgttg gcggtggcgg gcatgaccag cacgaggtcg gcccaccggg ccaggtcgag
     7561 gtgcgcgacc ccgggcgcct cgccgacgcc gtcgtcgtac gcgggctcgc cggtcaccgc
     7621 tgtgaacgcc ttggcggtga cgaacgaggc cgcggcggcc gagagcacga cgcggacctg
     7681 caggccgagc gcgaacctca tggcgaggat ggactggggc agggtgacca cgtcgctgga
     7741 tccgcaggcg gccacgagga cccgctggaa cggtgtcacc gggtgggctg cagacacggc
     7801 tgctctcctt cggcgggggt ggtggagtcg tcgagctggc tggcgaccag ctcggcgtag
     7861 acgccgcggg cggccagcag ctcgtcgtgg ctgccctgct cggcgatgcg gccgtcggcc
     7921 aggacgatga tcttgtcggc gttgcgtacg gtgctcagcc ggtgcgcgat gaccacgcgg
     7981 gtgcagcgca gagcggagat cgcctggtcg acgcggcgtt cggtggcgac gtcgaggtgg
     8041 ctggtggcct cgtcgagcag cagcaccgcc ggatcgccga cgacggcgcg ggcgatggac
     8101 agccgctggc gctgcccgcc ggacagggcc tggccgcgct cggcgacgcg ggtgtcgtag
     8161 cccatcggca tggcgtcgat gtcggcgtcg atgccggcga tggcggcggc ggcgcggatc
     8221 cgttcggcgg tcgcgctcgg gtcggccagc gcgacgttgc ggcggatcga gtcgcggaac
     8281 aggtagctct cctgcagcac cacgccgaac tggcggcgca gggcctgcgg cgcgatccgc
     8341 gcctgcggca cgccgtcgaa gctgatctcg ccttcggtcg gccggtacag gccggtcagc
     8401 agcatggcca gggtgctctt gccgcagccg gacgcgccca ccacggcgat cttctgcccg
     8461 ggcaggatgt cgaacgagac gtcgcgcagc acgtacgggc tctgcgcgtc gtagcggaag
     8521 ccgaccccgc ggacctggat cgcaccgcgc agccggggtg tttcgagggc ctcgccgtcg
     8581 ccggtctcgg ggcgggcggc gaacacgtcg cgcagccgct gcaggtgcga gacgaccgac
     8641 tgcagcacct gggcgctgga caccagcgac gacagcggca ccaggaacga catggccagg
     8701 gcctgcaggc cgagcatctc ccccaggctc atgccgccct cgaacatccg ggcggtgccc
     8761 agccacagca gggccagcgg cccggccagc ccgaccgcgg cggtgacgtt gccgacggtg
     8821 gacgacagcc ggttctgtgc ccggtcgacc cgcagcgccg cgtcgtagcg ggtcagccag
     8881 ccgtcgtaga cctgccgctc gacgcccatg gacttgacgg tcgcgatgcc cgacagcgcc
     8941 tccatcagcg cgctctcggc ctcggcctgc acgttgagct ggcggtggct gagccggatg
     9001 agccggctgt tgaccaccgc gacggccagc acctgcgcca ggccgatgcc tcccgccagc
     9061 agcgcgaact cactgtcacg cgtggccagc acggcgaagt agacggtgac cagaccgccg
     9121 tcgatgacgg cggtgagcac ctgcgcggtg accagctcgc gcagcaggat gctgctggac
     9181 agccgctgca tcaggtcgcc gctggagcgc tgctggaaga acgcgtacgg cagccgcagc
     9241 aggtgcccga acagccgggt catcagctcc cggtcgacgc gggtctgcag gttcaccagc
     9301 atcatcgacc gcaggtgcgc gaccgcgaac tgggtgagca ccagcgcgcc gatgccgatc
     9361 gccaggtacg gcatcagcga cgtctcgcgg gcgggcatga tctcgtcgaa cgcgacggtg
     9421 gtggccagcg gcagcgccag cccgagcagc tgcagcagca gcgacacggc gaacacggcc
     9481 ccgagcgcgg gcaggaaccg gccgaccgca gcgcgggcac gtcgcaaccg ctgccgcacc
     9541 gggatccgga ccggccggga cggtgcgctc gcgggctcgc cgggggtgag ggcgatgacg
     9601 gtcgcgccga ggctcgtggc gagatcgtcg ggggtgatga gcctgcggcc gagcgcgggg
     9661 tcgacgatgc gcgcgccgcg ccgcccgaca cgctcgacga ccacgaagtg atcgtgctcc
     9721 cagtgcgcga tcgcgggcag cggcacctgc gtgacggcct gcggggtggc ccggtaggcc
     9781 ttggcggtca ggccgtggcg ggtggcggcg tcgatgacgg cccaggcgct gacgccgtcg
     9841 cggccgacgc cgatgtcgtc gcgtacgccg gacagggtcg cgggcaggcc gtggcggcgt
     9901 agcaccatgg tcaggcaggc ggcgccgcag tcggcctcgg ccatctgcag caccacgggc
     9961 acgccgcgga tgcgccgcca ccagctcgcc agcagtcgtc tcatggcttg ctccaggtcg
    10021 tggtcggggc cgggggcgcg agcatcagca gtgcgggcac cgtctcgggc gcggccaggc
    10081 gcagcaggcc gtagccgacg ccggacaggc cggtcatgag ttcgggcgag gggtggccgg
    10141 tcgggttggc cgcgcgccag ccgtaggtcc ggccgtcgtc gaggatcgcc gcggccacgg
    10201 cggccacggt ccggtccggc tcgcccgcgg ccagcagcag gtcgaggttg cccaggtcgc
    10261 cgtggcacag cgagtggttg cgcccgaatc cgccggccag cgtcgtgcgc accgcggtgg
    10321 cgatctcggc ggtgagccgg tcgtgttcgc cgtccggcgt accggccgga acggacggag
    10381 cagagtcggg gtggatgccg agcgcggcgc ggatgcgcag ccgggacagc ccgacgccgg
    10441 gggcgccgtg gcaccaggtg aggctgaacc ggccgggttc gcgcaggtcc gcccagttgc
    10501 cgcgggccgg gtcgaagagg ctgcggtcgt gttgcagggc ggccagcgcg ccgtcgaggt
    10561 agcgctgctg cccggtggcg tgccacatcg ccgccagggc ggcggcctgg cccgcggtgc
    10621 cgtgggagaa gccaccgagg cgcggcccgc cgggcggcgg ctgcaggagc aggtccgcgg
    10681 ccctgctcgc caggggaagc acccggtccg tgtcgtgccc ggccgagagc agcgccagta
    10741 cgcagcctgc ggcgccgtcc acgacgtcga ggacggtccc ggtgccgacg agagcgtcca
    10801 gccgggtgat gatcaggtcg gcggtcgtgt gggcggaccg gtggccgagg gcggcgaggt
    10861 ggccgtagca gtaggacagg ccgctccagc cggtgaacgc accgatcgac gtaccggcga
    10921 ccgcccgctg ggcgatcctc gtggccagcc gtccggcggc gcggtcggcc gcgtcggcga
    10981 accggccctc gccggtctgc gcgccaagcc aggccaggaa cagcgcgatg ccggcggtgc
    11041 cgtcgtagag gtggtcggcg gcccggccca cccgccagcc gatgcctgcc ggggtgaggg
    11101 cgaaccagcc gtcgtggtcg gacagctcga cgatccggtc gccgatcgcg gcggcggcgt
    11161 cgagcgcgcg ccgccggacc ttcggcagcg ccgattcggg cgtgtcctcc cgggccggtt
    11221 ccccgagctg gacggcgagg tcgggcagct gccagcgtac ggcggcgtgc ggtgcgcccg
    11281 cgccgtcggc ctgggcggcg tacgcggcgc ggatcagcca gacctggcgg gccaggtcgg
    11341 tgtcgcccag cccgcgcagc cgccgccgtg cttcggccag cccgctgcgc accagcacgt
    11401 ccggcaccgg gtcgcccgtc ccggtgccca gcgaggtggc accggcgcgg gccgtgaacc
    11461 gcggcacgtc cccggcgtcg agatcggacc gttcggcggc gacgaagtcg cgtagcggcg
    11521 gcagctgggc caccccgctc cacagccagt cgagcagccg atcgcggtcc aggccgtcgc
    11581 gcaggtggtc ggtgtgcagg gccgcctcgg cgagcctgcg gtaggtgcgg gtgggccgca
    11641 gcaccacccg gatctcgtcg gcggcgaacg cggccagcgg gccgtcgtcg gctgccagca
    11701 cgccgcgcgc tgcgcgcagc agcgcgtagg tcacccggaa gccgtgcacg acgtcttcgg
    11761 tgtacgcggc gaggtcgacg ccgggtcccg cgacggcgtg gctgtgcgcg ggggcgagtt
    11821 ccagccgcat caggtcggtg ccgacgccga cccaccgcgt gcagccgcag gcgcgcccgg
    11881 cggccacggc gtcgccggtg ggcagggcgc ccacgccgag caccgagtcc gcgacggcgc
    11941 tgcgccgctc ggtcacggca ggcgtgaaca gcgtctccag gtcgatcggc acggggtgcc
    12001 cgccgtgggt gaccaggttc tcgtcgtgga agtcggtggc gccgagcgcg tacagcagcg
    12061 cgagcaggcc gccccggcgg cgggcgtacg ccgcggcgtc gccggtggac gtgtccgccg
    12121 ggacgaactc ggcccagccg tagcccgccc ggggcaccac ggcgcaggcg cgcaggtccg
    12181 cgccgcgctc gttgagccag tccacgaggt cggcgtagcg cgcttcgacg gtgacatcgc
    12241 gtggcttgta cacgatggtg actccgccgc tgaaccgggc gagcagcacg cgccgcccgc
    12301 cgtgatgcgg gtcgccggtc tcgtcggcgg cggtgagcac gccgagcggg gcgccgccgg
    12361 tgaaggtgtg ccgcagcagg gcggcgtcgg cggccagccg gtcgagcagc tcgcaggtgc
    12421 gtgcggccca gcggtcggcc gtgcccagca cctggcgggc cagcacgggg tacgccgtca
    12481 ggaacgccag tgccgcggcc ggctcgcgca ggcgcgcgaa gaacgtgtgg aagcgttcgg
    12541 ccgggccggc gggcgcctgc tgctcgtgca gccgcgcgat gttcagttcg agcacggccg
    12601 cccggctcag ctgcacgacc agctcgtcca gcaggccggg cacggtcgcc gcggcgacgg
    12661 tgtccgggtc gaacggggcg ccgggcgtgg cggcggccag gcgccgggcg tgctcggtga
    12721 cctgccgggt ggcgtgggcg acgaggggcg cggcgaccac cgcggcggcc gccatcggcc
    12781 ggtccgtggc ggcctcgatc ggcaggtcgg cccccggccc ggcgtagcgg cggcgcaggg
    12841 cggtgatcca gccggggtcc ccgccggcgc ggtggcgcag gtcgtcgggg gtgtcgtcga
    12901 gcagccggag cagcgccggc tcgtcgaggc ggtcggcggc gaggcgttcg gtccacaggg
    12961 cggtgccggt gaacgcgtcc agctcgcgcc aacgggtcag ccgccagcgg gcgcggtcgg
    13021 aggccgcacc gccggtgccg ggggcgggca gcgccagccg ttcgcgcagg ttgagtgcgg
    13081 catgcagggc catcgcgggg tgatgcctct ttccagttcg gatgtggacc cgagggtccg
    13141 ggccgtcgag cggcccggac ccccggatga gcgcactgcc cgctgccggg cgcgcggcgg
    13201 tgtcagcaca cgcagtggca gcacatgctg gtgtggccgt cgatggccgc gccgccggcg
    13261 acggtctgca gctcgtcgcg gctcatctcg accaggccgg ccgggtgcgc ggcctgcgac
    13321 agctcgggcg aggtggcgcg gtggaactcg tcggtccagt tgcggacgac gtcgctgatc
    13381 gacatggcga tcccctttgt ttctcggttc gtccgctcgc cgggttcggc gggcggctcg
    13441 ttcggtatcg agcatcggcc ggggcaaggg gtgcgcacat gagtggcggc tactccattc
    13501 cggagccgcc gcggcggccg tgcggggcgt gactgtcggc cgcgcgacgg gttgcctgcg
    13561 cggccacctg tccggaactt gactccaagg tcatctccgg catgaaggaa accttcagaa
    13621 acgcagttca gcggcggact gtcagctgcg cgaccggcta ctcaggaccg ttatcacagt
    13681 gagcccgccg tcgcggtcgg ttagcgttgc gaagcgccgg tacgggaccg cgcgccgggc
    13741 acgacgggtg ggaacgatgc cggacggacc gacgcatctc gcgcggctgg acagaccctg
    13801 gccgttcacc ggccggcagg ccgaacgggc cgcgatcgcc cggaccctgg ccggcgggcg
    13861 cggcgtgctg atcactggcg atcccggctc cggcaagagc cgtctgctcg acgaggtgct
    13921 caccggcgcc gacgacggca gccgcctcgt gctgcgggcc accgcgacct acggctggca
    13981 cgaggtgccg ttcggcgcgt tcgggcacct cgtcgccgaa cccgccgccc accccaccga
    14041 cctgctcacc gaggcgatgc ggcgcgtcga cgcgctcgcc cagggccgtt ccgtgctcgt
    14101 cggcgtcgac gacctcaact ggctcgacga cacctcgacc gccctgctgc agcgcatgag
    14161 caccgagacc gggctgcgcg tcgtggccac ggtccgcacc ggcgacctcg gccgctcccc
    14221 cgtcgcggcg ctgcgccgcc acagccgcct ggaccgcctc gacctcgcgc cgttcagcca
    14281 ggacgggttc gccgacctca tcaccgccgc cctcggcgac cccgccgacg gcctgacccg
    14341 caacgccctg tggcacctca cccagggcaa tccgctgctg ctgcgcgaga ccctgcgctg
    14401 cggcctggac agcggcgaac tggcccgcca ccacggcatc tggacctggc ccgtcgacga
    14461 ggcccaccac ccgcaccgct gcgacatgat cgccgagacc ggcggcaccc tcaccgcggc
    14521 cgaactccag gcgctgcagt acatcgcccg cgccggcgcc gcgccgctga ccgccctgga
    14581 ccggctgctc gaccccgccg ccgccgagag cctggaagaa cggggcatca tccacctcgt
    14641 cggcaccggc cgggacgcgt cgctggccat cgcccacccg ctgtacgccg aggtcgcgca
    14701 ggcgcacacc ggcgcgctgc gggaacggcg catgctgcgc gagctcgccg acgccctggc
    14761 gcagacctcg accggcaccg ccgaggacgc cgtgcacgtc accgcctggc gctgcgaagc
    14821 cggggatccg gtccccgccg ccgacgccgt cgccgccgcg cagtggttcc tggcccgtgg
    14881 cgacgccgcc cgcgccgccc ggatcgccgc ccgcgccgac ggcccgcacg ccgcctggca
    14941 actgggccgc gcgctggtcg cccaggaccg cgtcgaggcc gcgcagaccc acctgaccac
    15001 ggcgtacgag cagctcaccg acccgcacga gcgggccgag gccgccgcgc tgctggtgct
    15061 caacaccttc ctcggcctgc gccaggtcga cacggcccgc gacctgctcg ccaccgccgc
    15121 ggcggccctg ccgccggacg cccggcccgg cctgctggcc gccgaggcgg cgctggccgt
    15181 gctcaccgga tccgccgcgg ccgccgcgtc gacggtcgcc gcgctggacg agcacccgcc
    15241 ccgtgacctg gtgctgcgga tggccgtcgc gccgctgcgg ccgtacctgc tcatcgcggc
    15301 cgggcagccc gcccgcgcgg cggcgatgtt cgacagcggc caggcggccc cgccggcggt
    15361 gtggccggtc atgcgcgccg ccgcccagac ctgccacgtg caggcgctgc tactggccgg
    15421 gcaggcgccc cgggccgccg aactcgccgc cgggtactac cgcgatgcgc tgacccgcgg
    15481 cgcaccggac gccgtcgcgc tgctcgcgat gatcatcggc aagtgcgcgt accacggtgg
    15541 ccgcctcgcc gacgcccgcc gctggctgcg cgaggcccgc agcctcatcg acccgcacac
    15601 cctgttcccg atcagcgaga acgtgctgtc cacctacgcc tggaccgccg cgcagcaggg
    15661 cgacctcgac gacgcccgtt ccgccctcga ccagctcgcc gccgcgctcc ccccgcacgg
    15721 cgcccccgcc aaggaggccg cgctggccca ggcgtggctg gccgtctccg ccgggcagcg
    15781 cgacaccgcc gtacggaccc tgcgcgagca gctgcaggct tcgctctccc ggggcatgct
    15841 caccctggcc gccgagcgcc tgcacctgct ggcccggctg gaccccgacg tcgacaccgc
    15901 ccggcggctg cgcgagatcg cccatcagtg cgacagcccg ctgttcgggc tgtgggccga
    15961 gctcgccgac ggcctggcca ggcgtgatcc gatcgtgctg gaccacgtcg cgaccgcgtt
    16021 cgaggagcgc gggcacctgc ggctggcgat ggaggcgctg gcaccggcgg cgaccgcgta
    16081 ccagcgccgt ggcgacctgc ggcgggccaa cgccgtcacc catcgcatcc agctggtccg
    16141 cgagcagtgc gagggctggt ggccgcagtg gcatccggcc gcgccgccgg tcgcgagcgc
    16201 gctgacggcg cgggagcagg aggtgtgcga gctggccgcg tccggcctgg acaacgccgc
    16261 catcgcggcc cggctggtgc tgtcggtgcg caccgtggag aaccacctgc agcgggcgta
    16321 ccacaagctg ggggtggcgg gccgcacccg gctgcggctc gcgctcatgc ccgagacggc
    16381 cccgtccggc cgctgaggtg gtgcggcggc tacgccggtt cgcgtacgcc gcccgggtcg
    16441 ccgcctgtgt cgccctcacc cggctcgggt tcgaccggcg cctccggcag gacgtcgggg
    16501 gcatccggcg acagctcgcg cggatcgtcg gggatgggag ccgacgggtc gatcggcggg
    16561 tactgctcgg ggtcgagttc tggttggctc accgatcgcg tatccccacc cggctcggtc
    16621 ggcaaacgat gccgcgtggc cgcggaaaga tcacaccggt gatccctgtt cggcaggtgc
    16681 aaccggcacc ggccggtcag ccgtagcggg agtccgcgca gcctggaggc tccggagatc
    16741 ggcggcacgc tgctcggcct cctccagcga gtgcgagccg agttccgaga ccggcagccg
    16801 tcccacgccg tcgatctgaa gaatcggcgc gtacagcggc ctgcctccac ggaggaacac
    16861 ctgtccgcaa tcgatcgaac tgacgtggtc ccaggtcagc gtccggtccg gccggctgaa
    16921 gctccggacg agcagaccat cctgatcgat caccacgccc tgccggaggg cacgccagat
    16981 gccgaggaga ccgaccagcg tgagcgcgca tgccagtgcc acgccgagcc agtcacgctc
    17041 ggcaatgacg tgcccgttct tgaggtatga gagacctagc agcacgaaga catcggagac
    17101 gatgaacagc agaacgatcc tgatgcgcgg gcgtgccaca acacgtgtca ccggctcacg
    17161 ttagcaagct gacctcacgg gagatcggcc agctcaacgc ggccgcgccc gggtgacgaa
    17221 gccgtcagtc ggcgctcatt cgggcgaagc gacggtgacg gcttcatacc gccgggacac
    17281 gggtgagttc caggacgggg atggtgcgga tgcctgcggt cttctgggcg tactccgcga
    17341 agccggggta caggccggcc tgctcgtcgt acctgcggtc ccgttcgctg ccggtcagct
    17401 cacgcacact gacggaatag gtctcggtgc cccgctcgac ggctccgcgg ccggccgcgg
    17461 tgaggttgta gtaccagtcc gggttgtggg gcgcaccggc cttggacgcg aacacgtaga
    17521 cgacgtcctc gtcggtctcg tggggcaggt acatcatcgg gctgaccagc tcccgcccgc
    17581 tcttgcggcc ccggtggtgc accagcacca gcggcgctcc ggtgaacggg ccgcccacgc
    17641 ggccttcgtt cgcccggaac tcttcgatca ccttggtgtt ccagtcgctc atcgatgcac
    17701 ctcacgttcg tgtccacagg agtcgtgatc catcttcgcc gcccatcgtg gcggacgccg
    17761 cttccggact ggagcagggc gcgcccgcag ccctgaaaac cgaggtcatc gccgcaggcg
    17821 ccggcggcac gcggcggcga ggtggtggcg ccacagccac cacggcaggc tgcggccggg
    17881 ccgggcggat gacccggttt gagcaacctt cgcatcgggt ccgttccata cggccgccgt
    17941 actaggcttc gggcatggcc gagatccaga ccccgtctcc cgaggaagcc ttcgagctgc
    18001 tgctcgccgg caaccaccgc ttcgtcgccg gtgtgccgga gcacccgaat caggacgcga
    18061 cgcgccgggc cgagatcgct ccgggccagc gcccgttcgc cgtggtgttc gggtgctcgg
    18121 actcgcggct ggcggcggag atcatctttg atcgcggcct gggtgacctg ttcgtcgtgc
    18181 gtacggcagg tcatgtgatg ggtgccgagg tgctgggcag catcgagtac ggggtggacg
    18241 tgctcgacag cccgctggtg ctcgtgctcg ggcacgactc ctgcggcgcg gtggccgccg
    18301 cgtgcgccgc gctggagggc gggatggcgc cgtccggtta tgttcgcgac gtcgtcgagc
    18361 gggtgacgcc cagcgtgctc gcggcacggg ccgccggccg ggtggagccc gacgagatcc
    18421 tggccgagca cgtcaggcac acggtcgatc tgctcctgga tcgctcccgg gtgctggccg
    18481 agcgggtcga ggacggccgg gccgccgtgg tggggctctg ctaccggctg gccgacggca
    18541 gcgcccaggt ggtggccgcc cggggcctgg acgcggcgac cgcgcgacgg tgagcgagga
    18601 ggccgacaag gtcacggcgg cacgcgggca ccggccgcgc acccctgccc tcgccaagcg
    18661 ctgagcccga tgggcgcagc cgccgacgtc ccgcgtcccg gcaccggccc gcgcacggct
    18721 gccggcggct ggacgtggcg tgcgcaggtg ccggacggct ttcccggccg cgtccgataa
    18781 ccgttcgcgt acgggccgtc cgcgccccta gcctgggccg atgcgtgctg acgagtgggc
    18841 gaaggcccag gactggatcg ccgagaccct cgccgagcag ggcatcgcgg cgaccggccc
    18901 ggcggtggtc gaccgtgtgc gtccgtggtc gacgacggcc cgggtgccgg tcgcgggcgg
    18961 gcaggcgtgg ttcaagtaca acaacgccgg ctcgcgttac gaggccgcgc tgatgcggct
    19021 gctggccgcg atcgccccgc acgacatgct ggtgccgctc gccgtcgacg ccgagctcgg
    19081 ctggatgctg ctgcccgacg gcggcccgac catgcgcgag atcacgtccg acacgttcga
    19141 ccgcgaccgc tgggagcacc tgctgcgccg gtacgcggag ctgcagcgcg cggccgcccc
    19201 gcacgccgcg ggcatgctgg ccgccggggt gcccgacttc cggccgcaca ccgtcgccgc
    19261 ccagtacgag aagctgctca ccgacccgta cgtgctggcc aacctcgacg cgggcaagat
    19321 ggccggactg cacgagtggg tgccccggat cgagcggatg tgccggcggc tggccgccgg
    19381 cggcatcgcg cccagcgtgc agcacgacga cctgcacccg agcaacgtct tcgccgacgg
    19441 cgacggcggc ctgcgcttct tcgacttcgg cgacgccacc gtggcgcacc cgttcgggtc
    19501 gatgctggtc gtgttgcggg tggtgcaccg cgacgccaag gtcgagcaca aggacccgct
    19561 gctgtacgag ctgcgcgacc gctacctgtc cgcgtggacg gccgacggcc gcgacctggc
    19621 cgaactccgt gagctgtgcc aggacgccat cgtggtcgca aagatcggca aggccctgtc
    19681 ctaccagcgc tcgctgcagg acgcgaccga ggaggcgctg gccgagtacg gcgagggcat
    19741 ctacggatgg ctcgaagagc tcctcggccc ggacgtgatc tgacctgccg gctgatctcg
    19801 ctgtggcgct acgggaccct ggtggtgact tcgacgacct tgacggccca gtccagcgcc
    19861 gtcggcggcg gcatcagttc gacatcccgc tgtacggcgc gcatgccgag ccggtccagg
    19921 accccgttga tgccgggcaa cgtgtcgcgc gagaccgacc tcgacctctc ccccagcctc
    19981 ggcagggaga acggagccga gctgaacggc tcctcggcga cgagcagcac cagccagtcc
    20041 gtgacgaacg cgcccttctc gacgggacgg tccgggggca gcctgaaggc gacggcgccc
    20101 ccgtggcccg cctccgcggt ccagccccct tcgacgtact ccccggggaa caggttcgcg
    20161 tgcatgcggt accggtcggt caggtccagc aggacgcaga agagcctgcg gtcggtggtg
    20221 ttgcgcagcc ggatgaacac cgtcggcggc acccagctcg tgccgttcca cgtgtagtcg
    20281 agaacgaggt cgttcaccgg cggcggctcg tggccgcggg cgggacgcga gccgtcagcc
    20341 ggggccggga ccagttcgat ctggatcgcc tcggccagcg ccggggacgc gctcggcagg
    20401 ttgcggatct gcagccagcg ggcgatgtgc tccagccggc gtacggtctg ctcgatgccg
    20461 ccgtcatcgg cgccgaccgg gtcggccagc gatctgtcgt cgagaccgaa gatctgcacc
    20521 gtaccgcggg cgtggtcctg gcggacccgc agccgaagcc cggaggtgaa cgggtcggcg
    20581 ggccggacga gccggacatg cggtgagggc ccaccgccgg ggccgctgac ctggacggtt
    20641 cccgtcagcc gcgcagtgac gtccgggtcc gcctcgatcg acaccgcgac cggcgggagc
    20701 ggcacgtcgg tgaggaccat ctcgtagtgc ttctcctcgt ccggtgccca gccgaccggc
    20761 tcgacgacgc tgtgtcggac atgcacgctg agcacccgga cctgctgcaa cggtgcggcg
    20821 tggtgcaccc cgaaccgggc gtcggcgacg acaccatgca tcgccccggc gtccagctcc
    20881 caccggccgt ggaggtggcg catgctgatc cgggaggcgc gcggccgcag cgttccgccg
    20941 aggaactcga ggtcggcaag gtcgccgagc gcttccaggg tgggcacctg gctggagcgc
    21001 cagccctcga cgcggcagcg cgcgtggctg aacacctgcc ggtacgtggc gtgcgggccg
    21061 agccgggcga gcgcatgccc gagcgcctcg gtgaagacgc cgtgccagcc gtcggcgaag
    21121 ggccactccc tcgcccgctc ccactcgttg caggcggcga gcgccacgtg gccgggcaac
    21181 tgcaggccgg gggcggcacg cttcgggtcg gcggctgctg cgaccagctc gggcagcagg
    21241 tcgcgcaggg ccggtgcggt cgtcgacgcg ggggcgagcc tggctttcgt acccggcacc
    21301 gggacgtcgc gcataccact gcgggaatga cacgagtcca tgatcgtgac cagctgggcg
    21361 ccggtcgtga cgacctcatg ggccaggatg ccgagttcct tgtcgtacag gtcggccacg
    21421 tcggcgcggc tgtcgtggca cacgacggtc tggcacatgc cggcgctctc ggcgtaccag
    21481 atctcctcgg gcagcggcgc ggtcgagccg tgtccgctgt accagaacag cgcgatgtcg
    21541 ccggggccga gcccgccgag atgccggcgg aacgcctcga tgatcccggc ccgggtggcc
    21601 tgctcgtcca gcagcctctc gacgacgagg tcacccggcg cgacacggtc acgcaggagc
    21661 gcctcggcca gatccacatc gttgacgcac ccctgcaggt ccagctccgg cagcttgtac
    21721 cggtcgatcc cgaccagcag ggcgtggacc ttgggcataa cgcggtctcc tgtctggcgc
    21781 aggctgcgag cggccggtca gattcggtca gccgtactgt gacggacagg ctcaggtgtg
    21841 acccgcccgt cggcctgtca tgggccggtg tgtgcgaacg gggtccacac gctgggccgg
    21901 tcccggtgcc tgtccctcag ccggcgcacc gcatggtgca gtgcttcggc ggccaggtcg
    21961 gcccgcagca caccgccgtg agccacggcc tcgtagacct ccttggcgat ctgcgcggcc
    22021 tcgtcgtccc agatggacca cagcgtggcg atgacgtgcc ggtatccggt gtagtgcagg
    22081 gccgcggcga gggtgatcgc ctcatccggg aggttcgccc cgccgacggc ggtcttgcag
    22141 ccggacaggt aggcgaagtc gccacggtac tgctgggagc tgagatcggt cacggtgagc
    22201 gtgccgtcct gcacgagcag cccaccctgc gacggatcgg ccagattctg ctccccgtgg
    22261 caggcgaagt gcacccagcc gtgctcgcgc agtccgctca tgaccgtgtc gcgggtggcc
    22321 tgcgacccga ccagcgacgt gcaccggcca gcgaacagct gcgtgatgaa ctgttcctcc
    22381 gacctcacct tgggcaggtc cgcctggttc ggcgtctgcg gcatgccgac gaacagcatc
    22441 cgctcggagt caccatgcgg ctcccccgcg tcacccctgg cctgcaccag cgcgcgcagt
    22501 gtgggcgtgt aggaggagac gacccgatcc aggaccgcct caccggccgt actgtgatca
    22561 ccggcggcgt ggatcggcag cagcgccagc gggccggtcg ggcaccacca gatgcggggc
    22621 caggcgccgc tcggcgttcc ggtgtagccc aggtgtgcca gcaccttggc cgcgaacgcg
    22681 tcccacatcc agcgcaggca ccgatccagt gccgcctcga cggtgttccc cgagacggtc
    22741 acatcggcgt cgcgagtgaa gctcccccgc agcgtgtcac cctgccgggc cccgaccgcc
    22801 tccaggtacg cctgggcctg cgcggcgacg tcctcctggc gcaggtccgg cagctccacg
    22861 acctcgacgc cggacgtctt gacgatgagg gcgtcgcaac gccaccggct gatgttcagg
    22921 atgaccaccg gcccgccgtc cgcggccggg agcaggctct tcagcggggg cggccgcagg
    22981 aagtcctcga acccctcgag cgcgcgcacc tgctcgacga gctcgtccca ctcgcgggcc
    23041 agtgccatac ggcggtcgac atcctgcgtg aaccgctcgg agctgccagt agt
//
