LOCUS       NZ_AP023360            21083 bp    DNA     linear   CON 25-AUG-2024
DEFINITION  Catellatospora sp. IY07-71 chromosome.
ACCESSION   NZ_AP023360
VERSION     NZ_AP023360.1
KEYWORDS    RefSeq.
SOURCE      Catellatospora sp. IY07-71
  ORGANISM  Catellatospora sp. IY07-71
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Catellatospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Catellatospora sp. IY07-71
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8595826)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 381x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326265.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 05:22:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,732
            CDSs (total)                      :: 7,655
            Genes (coding)                    :: 7,563
            CDSs (with protein)               :: 7,563
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 20 of 92
            Pseudo Genes (incomplete)         :: 82 of 92
            Pseudo Genes (internal stop)      :: 2 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:09:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3813962
            Orig. end                         :: 3835045
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023360.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11083
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(1084..1425)
                     /locus_tag="CS0771_RS17145"
                     /old_locus_tag="CS0771_34200"
     CDS             complement(1084..1425)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="CS0771_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34200"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_244870849.1"
                     /transl_table=11
                     /translation="MNDTVATATAQAVPLVEVQVKGVFDAQAAPGVNRLLEEALELRPQ
                     QIVIDLAECETIDAAGILLLLDAHRRAVRDGGTVALRSPNERTRRSLRLARLDRMLQIL
                     PYQQGRVVA"
     gene            complement(1575..2744)
                     /locus_tag="CS0771_RS39675"
                     /old_locus_tag="CS0771_34210"
     CDS             complement(1575..2744)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020509697.1"
                     /locus_tag="CS0771_RS39675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34210"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_212841923.1"
                     /transl_table=11
                     /translation="MRKRLLSLVAGLITVLATTLLAPAAPASAAPLTKVLVFSKTAGFR
                     HSSIPNGIAAIQQLGTANGFTVTATEDANQFTTANLAQYQAVIWLSTTGDVLNTTQQTA
                     FQSYIAAGGGYVGIHAAADTEYDWAWYGGLVGAYFHSHPAIQNAQLRVEAPVNASTAHL
                     PSTWTRSDEWYNYRTNPRANVRVLMNLNEASYTGGNMGDHPITWCQAYGGGRAWYTGLG
                     HTEASFTDPDFTRMLLGGIQIAAGAVAADCSKPTPGPAGTSLRARANGRFVTAPNGGAS
                     ALIASATTVGTAERFEIIDRGSGNIAIRALVNSRYVCADNAGANPLIANRTAIGGWETF
                     ALIRNSNGSISLRAQANGRYVVAENGGAAPLIANRTSIGPWEQFDLITS"
     misc_feature    complement(2729..2740)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     misc_feature    complement(2938..2953)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    complement(3048..3062)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    3076..3090
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.7"
                     /tool="antismash"
     gene            3142..4361
                     /locus_tag="CS0771_RS17155"
                     /old_locus_tag="CS0771_34220"
                     /pseudo=""
     CDS             3142..4361
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072427.1"
                     /locus_tag="CS0771_RS17155"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34220"
                     /product="inositol-3-phosphate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTGIWLVGARGSVAVTSMVGALAIRASLAEPVGCVTELPALRHP
                     ALPALSDLVFGGHDVSCVGLVKKAQALVAAGVLPAAVVAAVADELSATEPEVRAAPRAA
                     PSTRRSPGSPPIWPTSGPGTAWTGSSWSTCPRPSRSPPRTPRTPTPPRWPPPCTPSRCC
                     RPARGMRTRRSPRAARTSTSRRPPGHGCPRSTSSPRSTGCRTPVTTARPGRRCSSRCSR
                     PCSRCATCGCAPGRAPTCSAAATAPRWPGRTPTRPRWPASSGCSRRRWATSRRATPAST
                     TCQTSAT"
     gene            4358..5200
                     /locus_tag="CS0771_RS17160"
                     /old_locus_tag="CS0771_34230"
     CDS             4358..5200
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475565.1"
                     /locus_tag="CS0771_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34230"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_212841924.1"
                     /transl_table=11
                     /translation="MRLRDLAQLVRAPAALSVPGDAVAGAVAAGSLSARTAGVAAASVC
                     LYWGGMAANDWADRELDAKERPERPIPSGRISPNTALAVAGGLTAAGLVLAGASGGRRT
                     LATAALLAGAIWTYDVKWKNSPAGPAGMALCRGLDVLMGGSGGDLRRAARPALAVAAHT
                     YAVTALSRREVSGADRTLPALTLGATAAVATQAAGRTGGPLPVLLAAWYAVRFGRAQRE
                     VLRQPDAPRVRAAVGAGITSLPALQGALIARDGRPLLGAVIATAAPAGAKLARKVSPT"
     gene            5197..6501
                     /locus_tag="CS0771_RS17165"
                     /old_locus_tag="CS0771_34240"
     CDS             5197..6501
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.5"
                     /locus_tag="CS0771_RS17165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34240"
                     /product="TIM barrel protein"
                     /protein_id="WP_212841925.1"
                     /transl_table=11
                     /translation="MSLRFGYGTNGFANHRLADALDVLAELGYTGVALTLDHAHLDPYA
                     VDVKDQVARTARLLAERELAVVVETGARYLLDPRRKHAPTFLHEDAPRRVDFLKRAVDI
                     AAELNAEAVSFWAGVRPAHVSADVAWQLLAEGCAEVVAYAAERGVAPGFEPEPGMLVET
                     LADWQRLRGLVGEQLKLTLDIGHCRANEPVTVEECVRIAGPHLVNVQIDDMRRGVHEHL
                     EFGTGEIDFPPVLRALADTGYTGLVAVELPRHSHAAPEVAARSLTFLRAAQWLGDALDK
                     LARDPAAIATLLPAARRGVGRAAAEDARVRLLHAAAPGAAAAAELYRYGDNDEKRAVLL
                     ACPAPDLVRDALRSNDTRLVAAALGPGARDLPAAEWRQGVLKSVFMGLPLSGVDGLAER
                     ADTELGRMLAALRHEREAAGRTMPADAVELLERLH"
     gene            6501..7352
                     /locus_tag="CS0771_RS17170"
                     /old_locus_tag="CS0771_34250"
     CDS             6501..7352
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020521541.1"
                     /locus_tag="CS0771_RS17170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34250"
                     /product="TatD family hydrolase"
                     /protein_id="WP_212841926.1"
                     /transl_table=11
                     /translation="MRIFDPHIHMTSRTTDDYERMAAAGVRALVEPAFWLGQPRTNPGS
                     FTDYFDALIGWEPFRASQYGIRHHCTIALNPKEANDPRCREVLPLLPRYLAKDRVVAVG
                     ETGYDSMTAEEDEVFAAQLQLAREHGLPALVHTPHRDKVTGTRRSLDAVKESGIDPGMV
                     VLDHLNEPTVGEVAGTGCWMGFSIYPDTKMSPERMVAILREYGLERMLVNSAADWGRSD
                     PLLTLRTGEAMLAAGFSADDVDRVLWRNPVEFYGQSGRLDLDEDAAAEATFAGNSILRG
                     GS"
     gene            7352..8470
                     /gene="eboE"
                     /locus_tag="CS0771_RS17175"
                     /old_locus_tag="CS0771_34260"
     CDS             7352..8470
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287903.1"
                     /locus_tag="CS0771_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34260"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_212841927.1"
                     /transl_table=11
                     /translation="MRLRDADGTTVHLAYCTNVHAAEDFDGVLSQLDRFAVPVRERLGT
                     DVLGLGLWLAAPVARALAEQPELRKRLRTELSARGLETVTLNGFPYQAFQAPVVKHDVY
                     LPDWTDPRRLRYTLDLALVLAELLPDDATRGSISTLPLAWREPWDKRRFGAARAQFGEL
                     AAGLARLDRTVRVALEPEPGCVVESTDQAVAALSAVADEHLGVCVDLAHLACGWEDPSD
                     AVAKLKSAGVPVVKVQVSQALEVEDPQAARQVLAAYAEPRFLHQTRSSAGERFDDLPLA
                     LASDAPGPWRIHFHAPLHAAALEPLRTSTQVLQEGLAALLTNSDCDHFEVETYTWDVLP
                     SAARPVDDAGLAAGIAAELAFAREQFAALGVS"
     gene            8470..9849
                     /locus_tag="CS0771_RS17180"
                     /old_locus_tag="CS0771_34270"
     CDS             8470..9849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020521539.1"
                     /locus_tag="CS0771_RS17180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34270"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_212841928.1"
                     /transl_table=11
                     /translation="MDRINPLVVLDVVGLTPRLLAHMPRLRAACADGFTARLDPVVPAV
                     TCSVQATFLTGQTPAGHGIVGNGWYFRDLGEVLLWRQHHALIEGERVWDAIRKARPGYT
                     VANICWWYAMGADVDWTITPRPIYRADGRKEPDCYTIPAELHDELPEFPLFTYWGPGAG
                     LPSSKWIADAAVHVMKTRDPDLTLVYVPHLDYDLQRFGPADPRSAQAAAALDEVLGPLL
                     DAAAARGATLVALSEYGITEVSRPVHVNRALRAAGLLHVHTQDGMEYLDPWTSRAFAVA
                     DHQIAHVYVRDPADLAAVAKICAELPGVGQVLDESGKAEQGLDHARSGELVLLAEPDAW
                     FTYYYWLDDKRAPDFATHVEIHRKPGYDPAELFFDPAAPGAAKARAAKALVRKKLGMRY
                     RMNVIGLDAGAQAVRGSHGLLPPTPDDAPLLLCSDPGPAVDRIAATDVKALLLRLAGST
                     P"
     gene            10001..11083
                     /locus_tag="CS0771_RS17185"
                     /old_locus_tag="CS0771_34280"
     CDS             10001..11083
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463797.1"
                     /locus_tag="CS0771_RS17185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34280"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_212841929.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-37, bitscore:
                     127.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAPAPTPLAARIDAVLAGFVDGQRLLWPDEDLRPMLDSLRRFI
                     LSGGKRLRPAFCYWAWRGTAAPAERADDQRAVTAGAALELFHCFALIHDDLIDDGTRRR
                     GAPSLHEEFAAAHARHGWRGDARAFGRNTALLCGDLCAMWAEELLAGCPVEPVRLGQAR
                     RLFAVMRTEAVAGEYLEVVAQAMADFGPGAPARAARVVQLKTGRYSVVRPLQIGATLAG
                     APDAVLDGLAAYGEPLGEAFQLRDDVLGVFGDPARTGKSTLDDLRQGKPTQLLAEAYAR
                     ADVRSRAVLSAHVGDPQLDEPGARLVREVVAGSGALAAVEERIAAARAESLRALDFLDL
                     APDARQALAGLAEFVASRSA"
     misc_feature    11120..11133
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.84"
                     /tool="antismash"
     misc_feature    11120..11134
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.34"
                     /tool="antismash"
     misc_feature    complement(11122..11135)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.98"
                     /tool="antismash"
     misc_feature    complement(11126..11146)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.49"
                     /tool="antismash"
     gene            11240..14374
                     /locus_tag="CS0771_RS17190"
                     /old_locus_tag="CS0771_34290"
     CDS             11240..14374
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020509696.1"
                     /locus_tag="CS0771_RS17190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34290"
                     /product="glycoside hydrolase family 95-like protein"
                     /protein_id="WP_212841930.1"
                     /transl_table=11
                     /translation="MNLSKSLRLALAALVAAGLGAAAPAAPALASPTDAAFNSSTGAFN
                     VNYAGYLSKHDIVYNRPNTNPLHGLTVGNGKTGAMVWANNGITAQVSGVDLSQQSAFAA
                     GLLNFNTSPALDSGSSAFQQRLSLYDGTLTTKYDSNRTVTMMGSPGSEVMGIHVDDTRG
                     GVSSATLELSLWDPNGVGNSADVPDLTTWRTVSTGSDSSAAWFSRGQADPNNFGYTFAA
                     TVEGASYTASVVNGTRVRLSITPTSSYTIWFTAASRINSPNLDSVAQAKSQLNAAKSTG
                     YSTTFTNYKNWWHNFWAKSFVQYSNSNGEADYLENVYYLSTYMIAAGGFGNYPVHFING
                     VFRATGDQTKWSNGYWYWNQRDVYNSFLASNHADMMAVFNRLYSRNYAALKAYTQTRYG
                     TDSLWVPETMGWDGNARGTINSDYVNDIYSTGTEAAYNMYLQYRYTNDTAYLQNTVYPY
                     MKDALRFYQNRFQLINGKYQMVNSNAHETYWDVRNAITDLAAVRLLAPLTIQVSTQLGL
                     DSGLRAGWQNLVDNLWPYQVSNNAWLPHDPPSSQVRNGENVSAELIWPYDRTGIGYPDY
                     NTAVNTWNVRPNPYANVWANDHAQAARLGMGDQAFNGMKLMLQRYQNYPNGMTNNTNGV
                     FEYLGIHLVAMNESLMQSYNDKIRVFPAVPSDSSFVGRFTLLAKDGFLVSSEREAGEIK
                     YVGLRSQFGKNATVVNPWGTQQVRVRRTSDNAIITTSSAAEISFATAANTVYVVERTAK
                     PLANYTAATLTGTQNNDAKSLRNTASTLGLGTGGGGGLVNNTELSYDAGWYHTTGRGYG
                     DYNDDTHHTNTVNAAASYTFTGTGIEYLSERFSDMGNVDVYLDNVFQANVNLNVSGARQ
                     AQVVVWSKTGLTNAQHTIRIVNKTTSVAIVDALRITTGGTPQPTGYVALRALANGQYVT
                     AANATTALIANSTTTGTAQQFEVVDRGGGNIALRARSNGQFVCAENAGANPLLANRATA
                     GSWETFALVRNSDNTVSLRATVNNLYVVAENAGAGSLIANRTAIGPWEKFDMITL"
     misc_feature    11258..11260
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14699..17971
                     /locus_tag="CS0771_RS17195"
                     /old_locus_tag="CS0771_34300"
     CDS             14699..17971
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019607.5"
                     /locus_tag="CS0771_RS17195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34300"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_212841931.1"
                     /transl_table=11
                     /translation="MPRSPRPRLAAGLAMLLLASLTAGAVSVTAAPAPAAAAPPPTSSF
                     EKVKLDGGLSMGEPIELSVLPDGKVLYINRGTSSGGGQVRLFNPATNSTTVALTLQLDA
                     RFEDGLIGITLHPQFATNRWVYLFYSPVATPLVNRISRFTFNTSTLVLDAASETKLIEW
                     PTERRLCCHSAGSMSWDSNGNLYFAVGDNTNSGGDSAGMAPIDERTSRDAQYDAQRTSG
                     NTNDLRGKINRIHPENNGTYTIPAGNLFAQGTANTRPEIYIMGVRNPYRIWVDKQANNT
                     LYWGEVGPDAGATIPNRGPAAYDEYNRASGPGNYGWPYCGGPNVAYNDWDFAANAPRGW
                     FPCGGSIGPVNNSPRNTGLQQLPATKGALVWEQHGGSVDWPALDNPGGCGSPNHAEVYH
                     YNPNLVSDVKWPQYYDNKLIITEYCRNWIKEVQFSNGNAATGNPTIIEPVVSGMQLVHP
                     IDMEFGPDGSLYLLEYGNGYFSGDVAAGLYKINYVAGGRSPIAVATANRDNGLAPLAVT
                     FSSAGSSDPDGDPLTYAWDFDNNGTTDSTAANPSYTYTTVGDKRARLTVNDGTGRSGTT
                     VLPIVVGNNRPVTTVGSIPNGGVYGWGDDITATASSTDAQDGTIACGNVVVRVALGHQE
                     HAHEEGQGTGCGFTFNTGPIHAGLDAVQFFVVRGSYTDRGATGTVPLTGEQQLTLWPKQ
                     WQAEHYVTLNGPRVVAQAAAEGGQRLGDIQNGESVRHHAVSLKGITSVKARVSSANAGG
                     VLSFRYDSTSGPEVARITVPSTGGWDNYTEITAPVTKPDDGTHDLYLVFTGSGTGALYD
                     VDSYTFVGSGVGTTPPGGGSDLAQGRPVTVSSTEAGANVAANAVDGNSATRWSSLYSDP
                     QWITVDLGASYAINRVRLNWEAAYARAYQVQVSSDNSNWTSVFSTATGDGGVDDLNVTG
                     TGRYVRMNGTQRATQWGYSLFDLNVYGTPAGGSTLLSRGRPVTVSSTEAGANVAANAVD
                     GNSATRWSSLYSDPQWITVDLGQHRSISRVVLNWEAAYATAYQVQVSTDNSNWTTVSST
                     TTGNGGTDDLTVSGNGRYVRVNGTARATQWGYSLWEFDVYGS"
     gene            18063..20171
                     /locus_tag="CS0771_RS38800"
                     /old_locus_tag="CS0771_34310"
     CDS             18063..20171
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020518998.1"
                     /locus_tag="CS0771_RS38800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CS0771_34310"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_244870850.1"
                     /transl_table=11
                     /translation="MRRRFLSVVAGVALAAGMALAAPLPASAAPLTKVLVFSKTAGFRH
                     SSIPNGIAAIQALGAANGFTVTATEDAAQFTTANLAQYQAVIWLSTTGDVLNATQEAAF
                     QSYIASGGGYVGIHAAADTEYDWSWYGGLVGAYFASHPATQQATIRVEDRANISTAHLP
                     PTWTRTDEWYNYRANPRSNVKVLSSLVESSYSGGSMGDHPITWCHHYGGGRSWYTGLGH
                     TEETYADANFRTMLLGGIQIAAGAKPADCRPETGYTAIFDGTQASLNQWRMAGPGGFTL
                     ADETLTSFGGMGLLWFPVRTYSNYSLKVDWMMPGDDNGGVFIGFPDPGNDPWGPVNAGH
                     EIQIDATDADPSRTTGSVYSFQAPNTTARAAALNPPGQWNTYEIGLHGQRVEIWLNGVK
                     INDYTSSRAIANGYVGVQNDGTGMDINYRNIRIKTDGGTPPATDIAQGKTATASSVESG
                     SAHVAANAVDGNAATRWGSAYTDPQWITVDLGGSYTINRVRLNWEAAFGRAYQVQTSPD
                     NATWTNVYTTTAGDGGVDDLTVSGTGRYVRVNGTQRATQWGYSLFDLNVYGTPVSGPQL
                     LSRNRPVTVSSVEPGSAHNGANAVDGNTGTRWGSAYSDPQWITVDLGTAKAISRVRLSW
                     ETAYGRAYQIQTSPDNSTWTTVYSTTTSDGGVDDVNLTGNGRYVRVNGTQRATQWGYSL
                     WELDVYGS"
     misc_feature    complement(20816..20831)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.26"
                     /tool="antismash"
ORIGIN
        1 ccccgcgcgc gccgcgggcc gcggcgaact cgtgcgcggc gtgcagcgtg ccgtggtgca
       61 ccggggtggc cagcagcccg tcgcaggcca ggtacagcgc ggccagctcg cgccggtccg
      121 ggctggtgcg cacgtagtgc accacggcct ggccgacgct ggcatgcgtg ccgttgagct
      181 tcgcgatcag gcggtcggtc agctcccgct gctcctgctc ctcgggggtg cgcggttcac
      241 cgcaggccac gtgcagcagc gccacggtgc ccggctccgg ccggtgctcg gcgaggaagc
      301 ggtcgaaggc gtgcagccgc tgctcgaccg cgtcggccgg gtcccacccg gcgatggaca
      361 gcagcaccgg cccgggcacc cgcagcgcgg cccggatctc ggccgcgcgt gcgcggacct
      421 gcggcagccg ggacagccgc cgcatgccgc cggtgtcggc gggcagcgcg caggccagta
      481 cccgcacccg ccggttgccg accgcgatct ggccgtcgcg caccggcagc ccgtgcaccc
      541 gccccgccag gtcgagcagg ttgtccacgg cccggcggtg cggcagcgcc accacgtcgg
      601 caccgagcag cccggacagc agctcgcggt gctcgggcag gcggccgaac gcctcggcgg
      661 gcgggaacgc gctgtgcagg tgcaccgcgg aggccaggtc gggccgcatc cggcgcagca
      721 gccggggcag cagctgcagc tggtgcccgt gcacccagac gatgccgccg gatcccgcgg
      781 acccggcgac ggtgtgcgcg agcgcgtggt tggcctgctc gtaaggctcg aaccagccgt
      841 ccgggaattc ggcccgctgg tggtggtaga gcgagcgcag caggcccgag ccgagccggg
      901 ccccggcgcc gtccggcatc gccgtccagg tgccccggcg cgcggcgacg aacgggcgca
      961 gcgaggcgag ggcgacgtcg acgtggtcgc tgctgtcgtc ggggtcggcg gcgggcaccc
     1021 ggtcacccgc gacgatcagg tcgtaggcgc gctcgtcccg cgccgtcggc tgtgcgccgc
     1081 cgctcacgcg accacccggc cctgctggta cggcaggatc tgcaacatgc ggtcgagccg
     1141 ggccagccgc aggctgcgcc gggtgcgttc gttgggtgag cgcagggcga cggtcccgcc
     1201 gtcgcgcacg gctcgccggt gcgcgtcgag cagcagcagg atgcccgccg cgtcgatcgt
     1261 ctcgcactcg gccaggtcga tcacgatctg ctgcgggcgc agctccagcg cctcctccag
     1321 gagacggttc accccgggcg ccgcttgcgc gtcgaatacg cccttgacct gcacctccac
     1381 cagcggcacc gcctgtgccg tggccgtcgc gaccgtatcg ttcacctggc tacctcctta
     1441 ccggcggagg tccctatgcc cggtccggtg cggagctaat cctcgaaagc atgacagttt
     1501 cgtgacaacc agcccacgac gtacggaccg gccggtggcg ccctgtcgcc accggccggc
     1561 cggccgggtg cccgttacga ggtgatcagg tcgaactgct cccacgggcc gatggaggtg
     1621 cggttggcga tcagcggcgc ggcgcccccg ttctccgcga cgacgtaccg gccgttggcc
     1681 tgtgcccgca ggctgatgct gccgttgctg ttgcggatca gcgcgaacgt ctcccagccg
     1741 ccgatcgcgg tgcggttggc gatgagcggg ttggccccgg cgttgtcggc gcagacgtac
     1801 cgcgagttca ccagcgcacg gatggcgatg ttgccgctgc cgcggtcgat gatctcgaag
     1861 cgctcggcgg tgcccacggt ggtggcgctg gcgatcagcg ccgacgcccc gccgttgggg
     1921 gcggtgacga acctgccgtt ggcgcgggcg cgcaggctgg tcccggccgg gccgggggtg
     1981 ggcttgctgc agtcggcggc gaccgcgccg gccgcgatct ggatgccgcc gagcagcatc
     2041 cgggtgaagt cggggtcggt gaagctcgcc tcggtgtggc cgaggccggt gtaccaggcc
     2101 cggccgccgc cgtacgcctg gcaccaggtg atcgggtggt cgcccatgtt gccgccggtg
     2161 tagctggcct cgttgaggtt catcagcacg cggacgttgg cacgcgggtt ggtgcggtag
     2221 ttgtaccact cgtcgctgcg ggtccaggtg gacggcaggt gcgcggtcga ggcgttgacc
     2281 ggcgcctcca cccgcagctg ggcgttctgg atcgcggggt gagagtggaa gtacgccccg
     2341 accagcccgc cgtaccaggc ccagtcgtac tcggtgtcgg ccgcggcgtg gatgcccacg
     2401 tatccgccac ctgccgcgat gtagctctgg aacgcggtct gctgggtcgt gttgagcacg
     2461 tcgccggtgg tggacagcca gatgacggcc tggtactggg ccaggttggc ggtggtgaac
     2521 tggttggcgt cctcggtcgc ggtgaccgtg aagccgttgg ccgtgccgag ctgctggatg
     2581 gcggcgatgc cgttggggat ggaggagtgg cggaagccgg ccgtcttgga gaagaccagc
     2641 accttcgtca gcggcgcggc ggacgccggg gccgccggcg cgagcagggt cgtggccagc
     2701 accgtgatga ggccggcgac cagggacagt aggcgttttc gcatgtggct cgctccttgc
     2761 ctgaggttag cgcggtgagc gggcggcgac cggcgtacgc cgcggcacgc cgggccggtc
     2821 ggccgcgggc gcgagcgggg aagcggggcg cgggcggcga ccgggacagc gcccccgggg
     2881 cgcgggcacg cccctggacg gcgttcgcgg aggtcacccg cgaaccggag ccggtcgccg
     2941 aacacggatc cgatatctat cggcatcgaa tcctatagga atcgtgcggc tgtgggaagt
     3001 ctcttccgtc cggttcggcc ctccgatttg tcaacagcgg ccgaactttt gctagatcag
     3061 aaaaaagtat gcatctctat ctagaaactt ttgctgacat ggatttaata tggccgccac
     3121 gaacgcgtta caggaggtcc tgtgcgtaca ggtatatggc tcgtcggcgc ccgcggatcg
     3181 gtcgcggtga ccagcatggt gggtgcgctg gcgatccggg cctccctcgc cgagcccgtc
     3241 ggctgcgtca ccgagctgcc cgcgctgcgc cacccggcgc tgccggcgct gtctgatctg
     3301 gtcttcggcg gccacgacgt gtcctgcgtg gggctggtca agaaggccca ggcactggtc
     3361 gccgcggggg tgctgcccgc cgcggtggtc gccgccgtcg ccgacgagct gtccgcgacc
     3421 gaacccgagg tgcgcgccgc cccgagggcc gcacccagca cgagacggtc acccggatcg
     3481 ccgccgatct ggccgacttc cggacccggc acggcctgga ccgggtcgtc gtggtcaacg
     3541 tgtcctcgac cgagccgctc gccgccccgc accccgcgca cgccgacgcc gccgcgctgg
     3601 ccgccgccct gcacaccgag caggtgctgc cgcccagcgc gcggtatgcg tacgcggcgt
     3661 tcaccacggg ctgcgcgtac gtcgacttca cgccgtccac cggggcacgg ctgcccgcgc
     3721 tcgaccagct cgccgcgttc caccgggtgc cgtacgccgg tcacgacggc aagaccgggg
     3781 agacgctgct caagtcggtg ctcgcgccca tgttcgcgat gcgcaacctg cgggtgcgct
     3841 cctggtcggg caccaacctg ctcggcggcg gcgacggcgc cacgctggcc cggccggacg
     3901 ccaacgcggc caaggtggcc agcaagcagc gggtgctcaa ggagacgctg ggctacgagc
     3961 cggagggcca cacccgcatc gactacgtgc cagacatcgg cgacctgaag accgcctggg
     4021 acctgatcac cttcagcggc ttcctgggca gccggatgcg gctggagttc acctggcacg
     4081 gctgcgactc cgcgctggcc gcgcccctgg tgctggacct ggcccggctc accgccgccg
     4141 cccacgcgca gggggcgtac gggccgctgc cgcagctcgc gtacttcttc aaggacccgc
     4201 tcggcgacgt cccgcacggc ctggccgagc agtgggagct gctctgccgc tgggtgcacg
     4261 ggtggccgct cgcggcctcc gactccggcc ccgacgagcc ccgcggcgcc gcagccgacg
     4321 ccgagcaggg cgcggaccag gacggggagc agccgcgatg agactccgcg acctcgccca
     4381 gctggtgcgc gcaccggccg cgctgtcggt gcccggtgac gccgtcgcgg gcgcggtcgc
     4441 ggcgggcagc ctcagcgccc ggaccgccgg ggtcgccgcc gcctcggtct gcctctactg
     4501 gggcggcatg gccgccaacg actgggccga ccgcgaactc gacgcgaagg agcggcccga
     4561 gcgccccatc ccgtccggcc ggatcagccc gaacacggcg ctggccgtag cgggcggcct
     4621 gaccgcggcg ggcctggtgc tggccggggc cagcggcggg cggcgcaccc tggccaccgc
     4681 cgcgctgctc gcgggcgcca tctggaccta cgacgtcaag tggaagaaca gcccggcggg
     4741 cccggccggc atggcactgt gccgagggct ggacgtgctg atgggcggca gcggcggcga
     4801 cctgcgccgc gccgcccggc ccgcgctcgc cgtcgccgcg cacacgtacg ccgtcaccgc
     4861 gctgtcgcgg cgcgaggtgt ccggggccga ccgcacgctg cccgcgctga cgctgggcgc
     4921 gaccgccgcc gtggccacgc aggccgccgg gcgtaccggc gggccgctgc cggtgctgct
     4981 ggcggcgtgg tacgcggtgc gcttcggccg ggcccagcgc gaggtgctgc ggcagccgga
     5041 cgcgccgcgg gtgcgcgccg cggtcggggc cgggatcacc tcgctgcccg cgctgcaggg
     5101 cgcgctcatc gcgcgcgacg gacggccgct gctcggggcc gtgatcgcca ccgccgcccc
     5161 ggccggggcg aagctcgcga gaaaggtgtc accgacatga gcctgcgctt cggctacggc
     5221 accaacggct tcgccaacca ccgtctcgcc gacgctctag acgtgctcgc cgagctcggc
     5281 tacaccggcg tcgcgctgac gctggaccac gcgcacctgg acccgtacgc cgtcgatgtc
     5341 aaggaccagg tggcacggac cgcacggctg ctcgcggagc gggagctggc ggtggtcgtg
     5401 gagaccggcg cgcgttacct gctcgacccc cggcgcaagc acgcgcccac cttcctgcac
     5461 gaggacgcgc cgcgccgcgt cgacttcctc aagcgcgccg tcgacatcgc cgccgagctg
     5521 aacgccgaag ccgtgtcgtt ctgggccggg gtccgccccg cgcacgtgtc cgccgacgtg
     5581 gcctggcaac tgctggccga agggtgcgcg gaggtggtcg cctacgcggc cgagcgcggc
     5641 gtcgcccccg gcttcgagcc cgagcccggc atgctcgtcg agaccctcgc cgactggcag
     5701 cggctgcgcg gcctcgtcgg cgagcagctc aaactcaccc tcgacatcgg ccactgccgc
     5761 gccaacgagc cggtcaccgt cgaggaatgc gtccggatcg ccgggccgca cctggtcaac
     5821 gtgcagatcg acgacatgcg ccggggcgtg cacgagcacc tggagttcgg caccggcgag
     5881 atcgactttc cgccggtgct gcgcgcgctg gccgacaccg gatacaccgg cctggtcgcc
     5941 gtcgagctgc cccggcactc gcacgccgcg cccgaggtcg cggcccgctc gctgaccttc
     6001 ctgcgcgccg cgcagtggct cggcgacgcg ctcgacaagc tcgcccgcga cccggccgcg
     6061 atcgcgacgc tgctgcccgc cgcacgccgg ggcgtgggcc gcgccgccgc cgaggacgcc
     6121 cgggtgcgcc tgctgcacgc cgccgcgccc ggcgcggccg ccgccgccga gctgtaccgc
     6181 tacggcgaca acgacgagaa gcgtgccgtg ctgctggcct gccccgcgcc ggacctggtc
     6241 cgcgacgcgc tgcgcagcaa cgacacccgc ctggtcgccg ccgcgctcgg ccccggcgcg
     6301 cgggatctgc ccgccgccga gtggcgccag ggcgtgctca agagcgtgtt catgggcctg
     6361 ccgctgtccg gggtggacgg gctggccgaa cgcgccgaca ccgagctggg ccgcatgctc
     6421 gcggccctgc gccacgagcg ggaagcggcc ggccgcacca tgcccgccga cgccgtcgaa
     6481 ctactggaga ggctgcattg atgcgcatct tcgacccgca catccacatg acctcgcgca
     6541 ccaccgacga ctatgagcgg atggcggcgg cgggtgtgcg agcgctggtc gagccggctt
     6601 tctggctcgg ccagccccgc accaatccgg gttcgttcac cgactacttc gacgcgctga
     6661 tcgggtggga gccgttccgg gcgagccagt acggcatccg gcaccactgc accatcgcgc
     6721 tgaacccgaa ggaggccaac gacccgcgct gccgggaggt gctgccgctg ctgccgcgct
     6781 acctggccaa ggaccgggtc gtcgcggtgg gcgagaccgg ctacgactcg atgaccgccg
     6841 aggaggacga ggtcttcgcg gcacagctgc agctcgcgcg cgagcacggg ctgcccgcgc
     6901 tggtgcacac cccgcaccgg gacaaggtca ccggcacccg gcgcagcctc gacgcggtca
     6961 aggagtccgg catcgacccg gggatggtgg tgctggacca cctcaacgag ccgaccgtcg
     7021 gcgaggtcgc cgggacgggc tgctggatgg gcttctccat ctaccccgac accaagatgt
     7081 cgcccgagcg catggtcgcc atcctgcgcg agtacggcct ggagcgcatg ctcgtcaact
     7141 cggccgccga ctggggcagg tccgatccgc tgctgaccct gcgcaccggc gaggcgatgc
     7201 tcgcggccgg gttcagcgcc gacgacgtgg accgggtgct gtggcgcaac ccggtcgagt
     7261 tctacggcca gtccggccgg ctcgacctcg acgaggatgc cgccgccgag gccaccttcg
     7321 ccgggaactc gatcctgcgc gggggttcgt gatgcggctg cgcgacgccg acggcaccac
     7381 cgtgcacctg gcctactgca cgaacgtgca cgccgccgag gacttcgacg gggtgctgtc
     7441 gcagctggac cggttcgcgg tgccggtgcg cgagcggctg ggcacggacg tgctggggct
     7501 gggcctgtgg ctggccgccc cggtcgcccg cgccctggcc gagcagcccg agctgcgcaa
     7561 gcggctgcgg accgagctgt cggcgcgcgg cctggagacg gtcaccctca acggcttccc
     7621 gtaccaggcg ttccaggccc cggtcgtcaa gcacgacgtg tacctgccgg actggaccga
     7681 cccgcggcgg ctgcgctaca ccctcgacct ggccctggtg ctggccgagc tgctgcccga
     7741 cgacgcaacg cgcggctcga tctcgacgct gccgctggcc tggcgcgagc cctgggacaa
     7801 gcggcgcttc ggcgcggcgc gggcccagtt cggcgagctg gcggccgggc tcgcccggct
     7861 ggaccggacg gtccgggtcg cgctcgagcc cgagccgggc tgcgtggtcg agtccaccga
     7921 ccaggccgtc gcggcgctga gcgcggtggc cgacgagcat ctgggcgtat gcgtcgacct
     7981 ggcgcacctg gcctgcggct gggaggaccc gtcggatgcc gtcgccaagc tgaagtcggc
     8041 cggggtgccc gtggtcaagg tgcaggtgtc ccaggcgctg gaggtcgagg acccgcaggc
     8101 ggcccggcag gtgctcgcgg cgtacgccga gccgcgcttc ctgcaccaga cccgcagctc
     8161 ggcgggggag cgcttcgacg acctgccgct cgcgctggcc tcggacgcgc ccggcccgtg
     8221 gcgcatccac ttccacgccc cgctgcatgc cgccgcgctg gagccgctgc gcaccagcac
     8281 ccaggtgctc caggagggcc tggccgcgct gctcaccaac tccgactgcg accacttcga
     8341 ggtcgagacc tacacctggg acgtgctgcc gtcggcggcc cgccccgtcg acgacgcggg
     8401 gctggccgcg ggcatcgccg ccgagctggc cttcgcccgg gaacagttcg ccgcgctggg
     8461 ggtgtcctga tggaccggat caatccgctg gtggtgctgg acgtcgtcgg gctgacgccg
     8521 cggctgctgg cgcacatgcc ccggctgcgg gccgcgtgcg cggacgggtt caccgcccgg
     8581 ctcgacccgg tcgtcccggc ggtcacctgc tcggtgcagg ccaccttcct gaccgggcag
     8641 accccggccg ggcacggcat cgtcggcaac gggtggtact tccgcgacct cggcgaggtg
     8701 ctgctgtggc ggcagcacca cgcgctgatc gagggcgagc gggtctggga cgccatccgc
     8761 aaggcccgcc ccggctacac cgtggcgaac atctgctggt ggtacgccat gggcgcggac
     8821 gtggactgga cgatcacgcc gcgccccatc taccgcgccg acggccgcaa ggagcccgac
     8881 tgttacacga tcccggccga gctgcacgac gagctgccgg agttcccgct gttcacgtac
     8941 tgggggccgg gcgcgggcct gccctcctcg aagtggatcg ccgacgcggc ggtgcacgtg
     9001 atgaagaccc gcgacccgga cctgaccctg gtgtacgtgc cgcacctcga ctacgacctg
     9061 cagcgcttcg gcccggccga cccgcgctcg gcccaggccg ccgccgcgct cgacgaggtc
     9121 ctcggcccgc tgctcgacgc cgccgccgcg cgcggggcga cgctggtcgc gctgtcggag
     9181 tacggcatca ccgaggtgtc gcgccccgtg cacgtcaacc gggcactgcg cgccgccggg
     9241 ctgctgcacg tgcacaccca ggacggcatg gagtacctcg acccgtggac gtcgcgcgcg
     9301 ttcgcggtgg ccgaccacca gatcgcgcac gtgtacgtac gcgaccccgc cgacctggcc
     9361 gccgtcgcga agatctgcgc cgagctgccc ggcgtcgggc aggtgctcga cgagtccggc
     9421 aaggccgagc aggggctgga ccacgcccgc agcggcgagc tggtgctgct ggccgagccc
     9481 gacgcctggt tcacctacta ctactggctc gacgacaagc gtgcccccga cttcgccacc
     9541 catgtcgaga tccaccgcaa gcccggctac gaccccgccg agctgttctt cgacccggcc
     9601 gcccccggcg ccgccaaggc ccgcgccgcg aaggccctgg tccgcaagaa gctcggcatg
     9661 cgctaccgca tgaacgtgat cggcctcgac gccggcgcgc aggcggtccg cggctcccac
     9721 ggcctgctcc cacccacccc cgacgacgcc cccctcctcc tgtgctccga ccccggcccc
     9781 gccgtcgacc gcatcgccgc caccgacgtc aaagccctcc tcctccgcct cgccgggagc
     9841 acgccgtgag gccggggtgt ggcagtttcg gggaaaccgc agggtcggtc gcgaggattc
     9901 gtgcagtttc cctgaaactg caggcaggcc gggcgggcac gcccgcgtgg tgggcgggga
     9961 cgcaggcggg ggtgcctgtg gggcgggcgg ggggtgggtc gtgacgctcg cgcccgcgcc
    10021 gacgccgctg gccgcgcgga tcgacgcggt gctggccggg ttcgtggacg ggcagcggct
    10081 gctgtggccc gatgaggacc tgcggccgat gctggattcg ctgcggcggt tcatcctgag
    10141 cggcgggaag cggctgcggc cggcgttctg ctactgggct tggcgcggca cggccgcccc
    10201 ggcggagcgg gccgacgacc agcgcgcggt gaccgcgggc gcggcgctgg agctgttcca
    10261 ctgcttcgcg ctgatccacg acgacctgat cgacgacggc acccgccgcc ggggcgcgcc
    10321 gtcgctgcac gaggagttcg cggcggcgca cgcgcggcac ggctggcgcg gcgacgcgcg
    10381 ggcgttcggg cgcaacaccg cgctgctctg cggtgacctg tgcgcgatgt gggccgagga
    10441 gctgctggcc gggtgcccgg tggagccggt gcggctgggc caggcgcggc gactgttcgc
    10501 ggtgatgcgc accgaggcgg tggcggggga gtacctggag gtcgtcgcgc aggcgatggc
    10561 cgacttcggg ccgggcgcac cggcccgcgc ggcgcgggtg gtgcagctca agaccggccg
    10621 ctactcggtg gtgcggccgc tgcagatcgg ggcgacgctg gccggggcgc cggacgcggt
    10681 gctcgacggg ctggccgcgt acggcgagcc gctgggcgag gcgttccagc tgcgcgacga
    10741 cgtgctgggg gtgttcgggg acccggcacg cacgggcaag tccaccctgg acgacctgcg
    10801 ccagggcaag ccgacgcagc tgctggcgga ggcgtacgcg cgcgccgatg tgcggtcgcg
    10861 tgcggtgctg tcggcgcacg tgggggatcc gcagctggac gagccggggg cacggctggt
    10921 gcgggaggtg gtggccggca gcggggcgct ggcggcggtg gaggagcgga tcgcggccgc
    10981 gcgagcggag tcgctgcgtg cgctggactt cctggatctc gcgccggacg cgcggcaggc
    11041 gctggcgggg ctggcggagt tcgtggcgag cagatcggcc tgaggcaaca ggatcgctca
    11101 gaaatccact gagcccacca atttccatat aaacagtgac atgtcttaag ctgatcttcc
    11161 tctatcctat aggatatttc atacacggtc tcgtaacagg ccggaaactc tgcccccatc
    11221 tcgcggaggt cataccccca tgaacctcag caagtcgtta cgactggccc tggcggcgct
    11281 cgtcgccgcg ggcctgggcg cggcagcccc cgccgcaccc gccctggcgt cgccgaccga
    11341 cgccgcgttc aacagctcca ccggcgcgtt caacgtcaac tacgccggat acctgtccaa
    11401 gcacgacatc gtctacaacc gcccgaacac gaacccgctg cacggcctga cggtcggcaa
    11461 cggcaagacc ggtgccatgg tctgggcgaa caacgggatc accgcccagg tgtccggcgt
    11521 ggacctgtcg cagcagtcgg ccttcgccgc cggcctgctc aacttcaaca ccagcccggc
    11581 cctggactcc ggctccagcg ccttccagca gcgcctgtcg ctctacgacg gcacgctgac
    11641 cacgaagtac gacagcaacc gcaccgtcac catgatgggc tcgcccggct ccgaggtgat
    11701 gggcatccac gtcgacgaca cccgtggcgg ggtgtcgagt gcgacgctgg agctgagcct
    11761 gtgggacccg aacggggtcg gcaacagcgc cgacgtgccc gacctgacca cctggcgcac
    11821 cgtgtccacc ggcagcgact cctccgccgc gtggttcagc cggggccagg ccgacccgaa
    11881 caacttcggc tacaccttcg ccgccacggt cgagggcgcg tcgtacacgg cgtcggtggt
    11941 caacgggacg cgggtgcggc tgagcatcac gccgacgtcg agctacacca tctggttcac
    12001 cgcggccagc cggatcaact ccccgaacct cgactcggtc gcccaggcca agagccagct
    12061 gaacgcggcg aagtccacgg gctacagcac cacgttcacg aactacaaga actggtggca
    12121 caacttctgg gcgaagtcgt tcgtgcagta ctcgaactcc aacggcgagg ccgactacct
    12181 ggagaacgtg tactacctgt ccacgtacat gatcgcggcg ggcgggttcg gcaactaccc
    12241 ggtgcacttc atcaacggcg tgttccgggc gaccggcgac cagaccaagt ggagcaacgg
    12301 gtactggtac tggaaccagc gcgacgtcta caactcgttc ctggccagca accacgccga
    12361 catgatggcg gtgttcaacc ggctctacag ccgcaactac gccgcgctga aggcgtacac
    12421 gcagaccagg tacggcaccg actcgctgtg ggtgccggag acgatgggct gggacggcaa
    12481 cgcccgcggc accatcaaca gcgactacgt caacgacatc tactccaccg gcaccgaagc
    12541 cgcctacaac atgtacctgc agtaccggta caccaacgac accgcgtacc tgcagaacac
    12601 ggtgtatccg tacatgaagg acgccctgcg cttctaccag aaccggttcc agctgatcaa
    12661 cggcaagtac cagatggtca acagcaacgc gcacgagacc tactgggacg tgcgcaacgc
    12721 gatcacggac ctggccgcgg tgcggctgct ggccccgctg accatccagg tcagcacgca
    12781 gctcggcctg gacagcgggc tgcgcgccgg ctggcagaac ctggtcgaca acctgtggcc
    12841 gtaccaggtc tccaacaacg cctggctccc gcacgacccg ccgtcttcgc aggtgcgcaa
    12901 cggtgagaac gtgtcggccg agctgatctg gccgtacgac cgcaccggca tcggttaccc
    12961 cgactacaac accgcggtga acacctggaa cgtgcggccc aacccgtacg ccaacgtgtg
    13021 ggccaacgac cacgcgcagg ccgcccggct cggtatgggt gaccaggcgt tcaacggcat
    13081 gaagctgatg ctgcagcgct accagaacta ccccaacggc atgaccaaca acaccaacgg
    13141 ggtgttcgag tacctgggca tccacctggt cgccatgaac gagtcgctga tgcagagcta
    13201 caacgacaag atcagggtgt tcccggcggt gccgagcgac tcgtcgttcg tcggcaggtt
    13261 caccctgctg gccaaggacg gcttcctggt cagctcggag cgcgaggccg gcgagatcaa
    13321 gtacgtgggc ctgcgcagcc agttcggcaa gaacgccacc gtggtcaacc cgtggggcac
    13381 ccagcaggtc cgggtgcgcc gcaccagtga caacgcgatc atcaccacgt ccagcgcggc
    13441 ggagatcagc ttcgccaccg ccgcgaacac ggtgtacgtg gtcgagcgca ccgccaagcc
    13501 gctggccaac tacaccgcgg ccacgctgac cggcacgcag aacaacgacg ccaagtcgct
    13561 gcgcaacacc gcctcgacgc tgggcctggg caccggcggc gggggcgggc tggtcaacaa
    13621 caccgagctc agctacgacg ccgggtggta ccacaccacc ggccggggct acggcgacta
    13681 caacgacgac acccaccaca ccaacaccgt caacgccgcg gccagctaca ccttcaccgg
    13741 caccggcatc gagtacctgt ccgagcggtt cagcgacatg ggcaacgtcg acgtgtacct
    13801 ggacaacgtg ttccaggcca acgtcaacct gaacgtgtcc ggcgcgcggc aggcgcaggt
    13861 ggtggtctgg tcgaagaccg gcctgaccaa cgcgcagcac accatccgca tcgtcaacaa
    13921 gaccacctcg gtggcgatcg tggacgcgct gcgtatcacc accggcggca ccccgcagcc
    13981 cacgggctac gtggcactgc gggccctggc caacggccag tacgtgacgg cggccaacgc
    14041 caccacggcg ctgatcgcca actcgaccac gaccggcacc gcccagcagt tcgaggtggt
    14101 cgaccggggt ggcggcaaca tcgcgctgcg ggcccgcagc aacggccagt tcgtctgcgc
    14161 cgagaacgcg ggcgccaacc cgctgctggc caaccgcgcc acggccggtt cctgggagac
    14221 gttcgcgctg gtccgcaact ccgacaacac ggtgagcctc cgggccacgg tcaacaacct
    14281 gtacgtggtg gccgagaacg caggagcggg ctcgctcatc gccaaccgca cggccatcgg
    14341 gccgtgggag aagttcgaca tgatcacact ctgattcgtg cggggggccg cgtccgtccg
    14401 gccccccgca ccgccacctc ggagccggtc attcggcgac ccggctccgg accgaccgtc
    14461 cgggctccgc ggcacgaccg cggcggcccg gtggcccggc cgggcaccag cgtcccgcct
    14521 ccacgggcgg ccgcgggcac gtgccgggtc ctcgaccccg agggaacgcg tcatggccgc
    14581 acccgtcgcc gaagcaccac gccctgcgcc gcgcccgcgg tggcaggtcg gccgatgggc
    14641 cgtgcgcacc cccgaggtcg cccgcccgat ccccgccgac ccccaccgga gcgtcgtcat
    14701 gccacgaagt ccccgccccc gcctcgccgc gggcctggcc atgctgctgc tcgccagcct
    14761 cacggccggc gccgtcagcg tcaccgccgc acccgccccg gcggccgccg cgccgccccc
    14821 gaccagcagc ttcgagaagg tgaagctgga cggcgggctg tccatgggcg agccgatcga
    14881 gctgtccgtg ctgcccgacg gcaaggtcct ctacatcaac cggggcacca gctccggcgg
    14941 cggccaggtg cgcctgttca acccggccac caactcgacc accgtggcgc tgaccctgca
    15001 gctcgacgcc cggttcgagg acgggctgat cggcatcacg ctgcacccgc agttcgccac
    15061 gaaccgctgg gtgtacctgt tctactcgcc ggtggccacg ccgctggtca accggatcag
    15121 ccggttcacc ttcaacacga gcacgctggt gctggacgcg gccagcgaga ccaagctcat
    15181 cgagtggccc accgagcggc ggctgtgctg ccactccgcg ggctcgatga gctgggactc
    15241 caacggcaac ctctacttcg cggtgggcga caacaccaac tccggcggcg actcggcggg
    15301 catggccccg atcgacgagc ggaccagccg ggacgcgcag tacgacgcgc agcgcacctc
    15361 gggcaacacc aacgacctgc gcggcaagat caaccggatc cacccggaga acaacgggac
    15421 ctacaccatc ccggcgggca acctgttcgc ccagggcacc gcgaacacgc gccccgagat
    15481 ctacatcatg ggcgtacgca acccgtaccg catctgggtc gacaagcagg cgaacaacac
    15541 cctctactgg ggcgaggtcg gcccggacgc cggcgcgacc atccccaacc ggggcccggc
    15601 cgcctacgac gagtacaacc gcgccagcgg ccccggcaac tacggctggc cctactgcgg
    15661 cggcccgaac gtcgcctaca acgactggga cttcgccgcc aacgcgccgc gcggctggtt
    15721 cccgtgcggc gggagcatcg gcccggtcaa caactcgccg cgcaacaccg gcctgcagca
    15781 gctcccggcg accaagggcg cgctggtgtg ggagcagcac ggcggcagcg tcgactggcc
    15841 cgcgctggac aaccccggcg gctgcggctc gcccaaccac gccgaggtct accactacaa
    15901 cccgaacctg gtctcggacg tcaagtggcc gcagtactac gacaacaagc tgatcatcac
    15961 cgagtactgc cgtaactgga tcaaggaggt gcagttcagc aacggcaacg cggccaccgg
    16021 caacccgacg atcatcgagc cggtcgtctc gggcatgcaa ctggtgcacc cgatcgacat
    16081 ggagttcggc ccggacggct cgctctacct gctggagtac ggcaacggct acttctccgg
    16141 cgacgtcgcg gcgggcctgt acaaaatcaa ctacgtggcc ggcgggcgct cgcccatcgc
    16201 cgtggccacg gccaaccggg acaacggcct cgcgccgctc gcggtgacct tctccagcgc
    16261 gggcagcagc gaccccgacg gcgacccgct gacctacgcc tgggacttcg acaacaacgg
    16321 caccacggac tcgaccgcgg cgaacccgtc gtacacgtac accaccgtcg gcgacaagcg
    16381 cgcccggctg accgtcaacg acggcaccgg ccgctccggc acgaccgtgc tgcccatcgt
    16441 ggtcggcaac aaccgtccgg tgaccaccgt cggttcgata cccaacggcg gcgtctacgg
    16501 ctggggcgac gacatcaccg ccacggcgtc ctccaccgac gcgcaggacg gcaccatcgc
    16561 ctgcggcaac gtggtggtcc gggtcgcgct gggccaccag gagcacgcac acgaggaggg
    16621 ccagggcacc ggctgcggct tcaccttcaa caccggcccg atccacgccg ggctcgacgc
    16681 ggtgcagttc ttcgtggtgc gcggcagcta caccgaccgc ggcgccaccg gcaccgtgcc
    16741 gctgaccggc gagcagcagc tcaccctgtg gcccaagcag tggcaggccg agcactacgt
    16801 gaccctcaac gggccgcgcg tggtcgccca ggccgccgcc gagggcgggc agcggctcgg
    16861 cgacatccag aacggcgagt cggtccggca ccacgcggtc agcctgaagg gcatcaccag
    16921 cgtcaaggcc cgggtctcct cggccaacgc gggcggcgtg ctgtccttcc ggtacgactc
    16981 gacgagcggc ccggaggtag ccaggatcac cgtgccgagc accggcggct gggacaacta
    17041 caccgagatc accgctccgg tgacgaagcc cgacgacggc acgcacgacc tgtacctggt
    17101 gttcaccggc tcgggcaccg gcgcgctgta cgacgtggac agctacacgt tcgtcggcag
    17161 cggcgtcggc accaccccgc cgggcggcgg cagcgacctg gcccagggcc gcccggtcac
    17221 cgtgtccagc accgaggccg gggccaacgt cgcggccaac gcggtggacg gcaactcggc
    17281 cacgcgctgg agcagcctgt acagcgaccc gcagtggatc accgtggacc tgggtgcgtc
    17341 gtacgccatc aaccgggtcc gcctcaactg ggaggccgcc tacgcacggg cctaccaggt
    17401 gcaggtgtcc agcgacaaca gcaactggac ctcggtgttc tccaccgcga ccggcgacgg
    17461 cggggtcgac gacctcaacg tcaccggcac cggccgctac gtgcgcatga acggcacgca
    17521 gcgggccacc cagtggggct actcgctgtt cgacctgaac gtctacggca ccccggcggg
    17581 cggcagcacg ctgctgtcgc gcggccgccc ggtcaccgtg tccagcaccg aggccggggc
    17641 gaacgtcgcg gccaacgcgg tggacggcaa ctcggccacc cgctggagca gcctgtacag
    17701 cgacccgcag tggatcaccg tggacctcgg ccagcaccgg tcgatcagcc gcgtggtcct
    17761 gaactgggag gccgcgtacg ccaccgccta tcaggtgcag gtctccaccg acaacagcaa
    17821 ctggaccacg gtctcgtcca ccaccaccgg caacggcggc accgacgacc tcacggtctc
    17881 cggcaacggc cgctacgtgc gggtcaacgg cacggcgcgg gccacccagt ggggctactc
    17941 gctctgggag ttcgacgtct acgggtcctg acccggcgcg gggaggcggt gctggcggcc
    18001 gcctccccgc catcgcgcag gcaccacctc ccgacctgga ccacccgatc caaggagcac
    18061 tgatgcgcag aaggtttctg tccgtggtcg ccggcgtcgc gctggcggcc ggcatggcgc
    18121 tggcggcgcc gctgcccgcg tccgccgcac cgctgacgaa ggtgctggtc ttctcgaaga
    18181 cggccggctt ccgccactcc tccatcccca acggcatcgc cgccatccag gcgctcggcg
    18241 ccgccaacgg cttcacggtc accgcgaccg aggacgccgc ccagttcacc accgccaacc
    18301 tggcccagta ccaggccgtc atctggctgt cgaccaccgg cgacgtgctc aacgcgacgc
    18361 aggaggccgc gttccagagc tacatcgcct cgggcggcgg ctatgtcggc atccacgccg
    18421 ccgccgacac cgagtacgac tggtcctggt acggcggcct ggtcggggcg tacttcgcct
    18481 cacatccggc cacccagcag gccaccatcc gggtcgagga ccgcgcgaac atctccaccg
    18541 cgcacctgcc gccgacctgg acccgcaccg acgagtggta caactaccgc gccaacccgc
    18601 gcagcaacgt gaaggtgctg tccagcctgg tcgagtcgtc gtactccggc ggcagcatgg
    18661 gcgaccaccc gatcacctgg tgccaccact acggcggcgg gcggtcctgg tacaccggcc
    18721 tcgggcacac cgaggagacg tacgccgacg cgaacttccg caccatgctg ctcggcggca
    18781 tccagatcgc ggccggggcc aagcccgccg actgccgccc ggagaccggc tacaccgcga
    18841 tcttcgacgg cacccaggcc agcctcaacc agtggcggat ggccgggccg ggcgggttca
    18901 cgctggccga cgagacgctg acgtcgttcg gcggcatggg cctgctgtgg ttcccggtgc
    18961 gcacctacag caactactcg ctgaaggtcg actggatgat gccgggcgac gacaacggcg
    19021 gcgtgttcat cggcttcccc gacccgggca acgacccgtg ggggccggtc aacgccgggc
    19081 acgagatcca gatcgacgcc accgacgccg atccgagccg gaccacgggc agcgtgtaca
    19141 gcttccaggc gcccaacacc accgcccgcg cggcggcgct caacccgccc ggtcagtgga
    19201 acacctacga gatcgggctg cacggccagc gggtcgagat ctggctcaac ggcgtgaaga
    19261 tcaacgacta caccagctcg cgggccatcg ccaacggcta cgtcggcgtc cagaacgacg
    19321 gcaccgggat ggacatcaac taccgcaaca tccgcatcaa gaccgacggc ggcacgccac
    19381 ccgcgacgga catcgcccag ggcaagaccg cgacggcgtc cagcgtggag tccggcagtg
    19441 cccacgtcgc cgcgaacgcg gtggacggca acgcggcgac ccgctggggg agcgcataca
    19501 ccgacccgca gtggatcacc gtggacctcg gcggctcgta cacgatcaac cgggtccgcc
    19561 tcaactggga ggccgccttc gggcgggctt accaggtgca gacctcgccc gacaacgcca
    19621 cctggacgaa cgtctacacc acgaccgccg gtgacggcgg cgtggacgac ctgaccgtct
    19681 ccggcaccgg ccggtacgtg cgggtcaacg gcacccagcg ggccacccag tggggctact
    19741 cgctgttcga cctgaacgtc tacggcaccc cggtcagcgg cccgcagctg ctgtcgcgca
    19801 accgcccggt gaccgtctcc agcgtggagc ccggcagcgc gcacaacggc gccaacgccg
    19861 tggacggcaa cacgggcacc cgctggggca gcgcctacag cgacccccag tggatcaccg
    19921 tcgacctcgg cacggccaag gcgatcagcc gggtccggct gagctgggag acggcctacg
    19981 ggcgggcgta ccagatccag acctcgcccg acaacagcac ctggaccacc gtctactcga
    20041 ccaccaccag cgacggtggc gtcgacgacg tgaacctgac cggcaacggc cgctacgtgc
    20101 gggtcaacgg cacccagcgc gccacccagt ggggctactc cctctgggag ctcgacgtct
    20161 acggcagctg agttgccggc atgcgctctg cgcgtgcggc tttcggcctc tcagcccacg
    20221 tcggaccagg gttaagaagg gcaccttcca ctacggaaag cgataagaag gtgcccttcc
    20281 ttccccgtcc cgccccggtg cgtgccccgc gcgccgggga tcccaccccc ggaaggaaac
    20341 ccctcgatga gacacgtccc ccggtggcgg ctgtggtcca ccgccgtcgc caccctggcc
    20401 gcgagcgtcg cggtctccgt cgcggcggga gcgcccgccg cgacggcggc cccgatcccg
    20461 gccgccgact accagcaggt gtcgctggcc accggctcgg ccgagctggg cgagccgatg
    20521 tccctcgccg tcctgccgaa ccggtcggtg ctgcacaccg cccgcgacgg cacgatccgg
    20581 gtcaccgacg tcaacggcaa cacccggcag gcgggcaagc tgtcggtgta cacccacgac
    20641 gaggagggcc tgcagggcat cgcggtcgac ccgggcttcg ccaccaaccg ccacatctgg
    20701 gtctactact cgccgccgct gagcaccccg tccggcgacg ccccggtcac cggcaccgcc
    20761 accacctgga acacctggaa gggccacctg cggctgtccc ggttcacgct caactcggac
    20821 gacaccgtca acctggccag cgagcgcatc acgctgcagg tcgacaacga ccgggggcag
    20881 tgctgccacg tcggcggcga catcgacttc gacgcggcgg gcaacctcta cctgaccacc
    20941 ggcgacgaca cgaacccgtt cgagtccagc ggctacaccc cgatcgacga gcgcaccgac
    21001 cgcaacccgc agttcgacgc gcagcgcacc tcgggcaaca ccaacgacct gcgcggtaaa
    21061 gtcctgcgga tcaggccgca ggc
//
