LOCUS       NZ_AP023358            23993 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Micromonospora endophytica strain NBRC 109090 chromosome, complete
            genome.
ACCESSION   NZ_AP023358
VERSION     NZ_AP023358.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora endophytica
  ORGANISM  Micromonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Jishengella endophytica NBRC 109090
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6586761)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 293x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326245.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 14:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,248
            CDSs (total)                      :: 6,184
            Genes (coding)                    :: 5,715
            CDSs (with protein)               :: 5,715
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 469
            CDSs (without protein)            :: 469
            Pseudo Genes (ambiguous residues) :: 0 of 469
            Pseudo Genes (frameshifted)       :: 323 of 469
            Pseudo Genes (incomplete)         :: 166 of 469
            Pseudo Genes (internal stop)      :: 12 of 469
            Pseudo Genes (multiple problems)  :: 30 of 469
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:19:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4913871
            Orig. end                         :: 4937864
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023358.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23993
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="terpene"
                     /region_number="7"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23993
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10822
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10822
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5822](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5822)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(347..361)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    348..362
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.33"
                     /tool="antismash"
     gene            891..1568
                     /locus_tag="Jiend_RS23035"
                     /old_locus_tag="Jiend_47770"
     CDS             891..1568
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007464029.1"
                     /locus_tag="Jiend_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47770"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_111243043.1"
                     /transl_table=11
                     /translation="MAKRRKVGNLMALAVLSVLAQRPMHPYEIATALRGWGKDQDMPIK
                     WGSLYTVVGNLDRHGFIAAAESVRAGRRPERTVYRITDAGRAELVDWARELLATPMTEY
                     PRFRAGLSVLAALHPDEAAELLRQRLHQLVDNLATARAALAGHATEVPRLFLVESEYDL
                     VLGEAEASWIRALLAEFDAGTFPGLDQWRTFHETGELPAEVAALAERTSTPERSDSPDD
                     TSS"
     cand_cluster    1488..23993
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1488..23993
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[11487:13993](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11488..13993
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            1728..2933
                     /locus_tag="Jiend_RS23040"
                     /old_locus_tag="Jiend_47780"
     CDS             1728..2933
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007464030.1"
                     /locus_tag="Jiend_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47780"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_111243023.1"
                     /transl_table=11
                     /translation="MTDVRTAIIIGGGIAGPVAALALKRAGITATVYETYPNTAGGIGG
                     TLALAPNGVAALRIVGADQLVIDLATPIHRTVLAFGANRIDLPVLPGVPPLRVVHRNAL
                     SGLLHQRAEAEGVPIEYGRRLVDARQTPTGVTARFADGSTASADLLIGADGVHSTVRAL
                     VDPQAPGPRYTGVLGFESVASHPVDAEPGTMTFAFGRRGYYLYWPEPGGGTRWGANLPQ
                     QRPLSLAEARAIRPAEWWNRLRESYADDDPGAALIRTSDPDELQVSGSLHIMPRVPHWH
                     RGRMVLVGDAVHAPSNSSGQGASLAVESAVQLARCLRDLPDLPAALAAYERLRRARVEG
                     IAARAARINQAKAPGPMGRVVMPLMMRLLMRVAMKPERILGPEQRYTIDWAASAATERS
                     PA"
     gene            complement(2980..3504)
                     /gene="mug"
                     /locus_tag="Jiend_RS23045"
                     /old_locus_tag="Jiend_47790"
     CDS             complement(2980..3504)
                     /EC_number="3.2.2.28"
                     /GO_function="GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /gene="mug"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734922.1"
                     /locus_tag="Jiend_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47790"
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="WP_223256748.1"
                     /transl_table=11
                     /translation="MAAAADRTLPDVIATGLDVLFVGINPGLWSAATGWHFARPGNRFW
                     PALHRGGFTPRLMHPSEQGELPELGLGITNMVDRASARADELTPAELLAGAQTLTAKVA
                     RYRPRWVAVVGVTAYRIGFARPKAGFGPQPEPLADARLWVLPNPSGLNAHYTPQTLGAA
                     FAELRQATRQQ"
     gene            complement(3678..4439)
                     /locus_tag="Jiend_RS23050"
                     /old_locus_tag="Jiend_47800"
     CDS             complement(3678..4439)
                     /NRPS_PKS="Domain: PKS_KR (8-151). E-value: 6.4e-09. Score:
                     27.9. Matches aSDomain:
                     nrpspksdomains_Jiend_RS23050_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815297.1"
                     /locus_tag="Jiend_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47800"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_111243021.1"
                     /transl_table=11
                     /translation="MDLGLTDRVYVLTGASRGLGHATAQCLVADGARVVLAARRDDAVA
                     TAVADLGGPERAVGITADLADPDTPERLVAAARQHFGRLDGALVSVGGPPPGSAASIDD
                     QQWRQSFETVFLGSVRMVRTVATALPDGGAIALVLSTSARSPVPGLGISNGLRPGLAGV
                     AKDVADEYGPRGVRVVGLLPGRIMTDRNRELFAASGDPERARADAEAGIPLRRIGEPAE
                     FGRVAAFVLSPAASYLTGVTIPVDGGALRGL"
     aSDomain        complement(3987..4415)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Jiend_RS23050_PKS_KR.1"
                     /evalue="6.40E-09"
                     /label="Jiend_RS23050_PKS_KR.1"
                     /locus_tag="Jiend_RS23050"
                     /protein_end="151"
                     /protein_start="8"
                     /score="27.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VYVLTGASRGLGHATAQCLVADGARVVLAARRDDAVATAVADLGG
                     PERAVGITADLADPDTPERLVAAARQHFGRLDGALVSVGGPPPGSAASIDDQQWRQSFE
                     TVFLGSVRMVRTVATALPDGGAIALVLSTSARSPVPGLG"
     CDS_motif       complement(4320..4415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Jiend_RS23050_0001"
                     /evalue="3.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="Jiend_RS23050"
                     /protein_end="40"
                     /protein_start="8"
                     /score="19.9"
                     /tool="antismash"
                     /translation="VYVLTGASRGLGHATAQCLVADGARVVLAARR"
     misc_feature    4434..4448
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            complement(<4691..5004)
                     /locus_tag="Jiend_RS23055"
                     /pseudo=""
     CDS             complement(<4691..5004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788249.1"
                     /locus_tag="Jiend_RS23055"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTADTPLAHRQAQLVAALVTGATPPPGFAPGPLAAARAALLRKRA
                     GEAARHWPLLAAGLGPRWPATFTEWAAGRPNPGGLRDGWDLARALQARAALPRWPPRNW
                     "
     gene            complement(5001..5822)
                     /locus_tag="Jiend_RS23060"
                     /old_locus_tag="Jiend_47820"
     CDS             complement(5001..5822)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018802926.1"
                     /locus_tag="Jiend_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47820"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_111244431.1"
                     /sec_met_domain="DUF692 (E-value: 5.3e-80, bitscore: 267.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPEGVGIGWRPEIDGFVAELPGLRFVEVIAEALPRSGPPPHGL
                     AALRERGVAVVPHGVRLSLGGAQPVEPARVAHLAAVAELVAAPLVSEHIAFVRAGGLEA
                     GHLLPLPRTREAVDVVCANVARTQAELPVPLALEPIAALFDWPDDELDEAAFLTEILDR
                     TGALLLLDIANVYANARNRGDDPLALLAGLPLDRIAYLHIAGGAEQGGYYHDTHTDPVP
                     PQVLDLLTELCARHRPPAVLLERDGHYPPATDLRAELDAVAHAAGFPLVTR"
     gene            complement(5819..6751)
                     /locus_tag="Jiend_RS23065"
                     /old_locus_tag="Jiend_47830"
     CDS             complement(5819..6751)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583042.1"
                     /locus_tag="Jiend_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47830"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_111244419.1"
                     /transl_table=11
                     /translation="MTRLAADFDTWGIPSSTFLACYLTAALLLVAGVLIHRRSLLAGRS
                     APAADQLGPQQVAYLNGREELAVWTSLGTLRSQGVIGVAPDRRLTVDGPLPPAASQLDR
                     AIHYAAAQGVHGRDLRRTEWVERALTELRDGLDRHDLLLSPTRRAALRLGPLLLSALLL
                     LGVARIVAGLANDRPIWYLVLIVGALTVVTTVLFVRVPWRTRAADNALRTLRTRHRHLA
                     PASNPAYSLYGASGVAMATGLFGVASLWALDPVFAAQAEIELQTKAAAASSGASAAGTG
                     GCGSNSGDSGGGGGCGGGGGGCGGGGCGG"
     misc_feature    complement(6779..6795)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.71"
                     /tool="antismash"
     misc_feature    6830..6847
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.5"
                     /tool="antismash"
     gene            complement(6844..7416)
                     /locus_tag="Jiend_RS23070"
                     /old_locus_tag="Jiend_47840"
     CDS             complement(6844..7416)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018727348.1"
                     /locus_tag="Jiend_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47840"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_111244420.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILAAARACFARHGYEGATVRRLEEATRLSR
                     GAIFHHFRDKDSLFLAVAEDDAATMVETVARNGLVQVMRDLLARAISPDTTGWLGSQLE
                     VSRRLRTDPAFAKRWAERSAAIAEATRERLVRQREAGVLREDVPIDVLARFLELAYDGL
                     VLHLAMGRPAGDLGPVLDLVEEAVRRR"
     gene            7580..8224
                     /locus_tag="Jiend_RS23075"
                     /old_locus_tag="Jiend_47850"
     CDS             7580..8224
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583043.1"
                     /locus_tag="Jiend_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47850"
                     /product="HAD family hydrolase"
                     /protein_id="WP_111244421.1"
                     /sec_met_domain="HAD_2 (E-value: 6.3e-13, bitscore: 47.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRAGSFRTWAERFLDSIGAPPGDIDWLLSIDA
                     DGLTDRWDVADAIRDRYQLRIPSIDLVEELHDGVVEFTRLDPLVACALRIADDAGWMPV
                     VVTNGTVRLQDTKIRRTGLDRYIADWVISEEAGVSKPNPRIFALAAQRARMPLRGAWVI
                     GDGPEADIGGATAVGLPSIWLHRGRPWTDARFAPTATVDTVIAAIATIMGA"
     gene            8407..9327
                     /locus_tag="Jiend_RS23080"
                     /old_locus_tag="Jiend_47860"
     CDS             8407..9327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583044.1"
                     /locus_tag="Jiend_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47860"
                     /product="RIO1 family regulatory kinase/ATPase"
                     /protein_id="WP_111244422.1"
                     /transl_table=11
                     /translation="MRDHDFPAWERRNRGKRRFDDDEPHLLKRSRPAETPADPEPDPGP
                     AWSSWDDAVHGPQPHPAWLVTELAARDTELGVLKTGKEAEVHLVRRAVPDTDRSCLLAA
                     KRYRDPRHRLFHRDAGYLEGRRVRRSREMRAMVGRTAFGRQMIAGQWAAAEFGALARLW
                     EIGSRYGTINVPYPVQLRGTELMLEFLGDPDEGRAAPRLAELRPDPTELRDLWAQLVDA
                     LVVLARAGYAHGDLSPYNLLVCAGRLVLIDLPQVVDVVANPQGREFLARDVRIVATWFV
                     ARGLPPGLADPSALTELLSREAGLR"
     gene            complement(9438..9686)
                     /locus_tag="Jiend_RS23085"
                     /old_locus_tag="Jiend_47870"
     CDS             complement(9438..9686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287422.1"
                     /locus_tag="Jiend_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47870"
                     /product="DUF2630 family protein"
                     /protein_id="WP_111244433.1"
                     /transl_table=11
                     /translation="MDDKTILSRISDLVDEEHRLRATAQAHEAGTDDEARTRLRELEES
                     LDQCWDLLRRRRAARQAHGDPDAQGARPVPEVERYLQ"
     gene            10124..11491
                     /locus_tag="Jiend_RS23090"
                     /old_locus_tag="Jiend_47880"
     CDS             10124..11491
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734913.1"
                     /locus_tag="Jiend_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47880"
                     /product="cytochrome P450"
                     /protein_id="WP_111244423.1"
                     /sec_met_domain="p450 (E-value: 2.8e-66, bitscore: 222.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVHTRRAGSIPLRHVVPSLMRDPARALVEFGDRSGGEVVKLNLG
                     SFRPYLITHPDHLQRVLREKSGNYVRAGDGLQWRPLKRLFGEGILSDGEYWTNSRQILQ
                     PLFTARRIDGLVDRLAVAIEEAIDELAEPARTGQPVDMGTVQAEIVCSAIMRVFFDNKI
                     TVPDAMRIMEAQDAIAWSVMPRIMVPWAPNYAPMPGDRTFRRAVQLIDDLLLPTVRAAR
                     DTAHEGADDIISTLWRGRTEDGGRLDERQVRNDTVAMVATTTETTISVLTWLWPHIEQD
                     PTVATRLYEELDRVVGDQPVRREHLRELRYLRQVLDELLRLYPIGWLFPRRAVEEDVIG
                     GVRIPAGATLVVSPLITQRMSMFWDRPEVFDPDRFSPEASRGRPKYAHFPFGGGPHQCL
                     GMHLFYLEATLIVATLLSRFRFRLRRSGVPGIKVAAALRPLDRVEVTLRPVQGVAA"
     gene            11488..12387
                     /locus_tag="Jiend_RS23095"
                     /old_locus_tag="Jiend_47890"
     CDS             11488..12387
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734912.1"
                     /locus_tag="Jiend_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47890"
                     /product="terpene synthase family protein"
                     /protein_id="WP_111244424.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-12, bitscore: 45.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARTEPPDAGGDQLLIAAEQGRICALAAQGQRDLAKVAASYPDL
                     FPAKPFDAALFGNVAMAIAFGAPWCDPAQLRITNRVVLWGFAVDWLIDHEARSRDEIDR
                     LTARCLAVADGGSPEEGDALGAFLAELRDELAAVPAFAEHRHRWRDEIRTVLVAMGREW
                     DWKQQPDQLPSFAEYLDNAANLACTVVNVVHWIHTDDPATLKHLDALLAASDQVQRILR
                     LVNDLGTYERDVRWGDLNALLLVPRAEVEQRIIELVAEARAMLEPLRDSVPVPADYLAR
                     QIGFSSGFYRSTDFWGVS"
     gene            12384..13493
                     /locus_tag="Jiend_RS23100"
                     /old_locus_tag="Jiend_47900"
     CDS             12384..13493
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Jiend_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Jiend_47900"
                     /product="hypothetical protein"
                     /protein_id="WP_249412212.1"
                     /sec_met_domain="T2TS (E-value: 4.1e-44, bitscore: 149.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVAPAVGAETGPSVTAAARDLVALLEREPAGQVSNSVYETGRL
                     VADAPWLDGHGRRLAYLLAQQSADGSWGPAGGYALVPTASAVQGLLAELVRADPAGTAA
                     RAELAAATARGLAALARRLADGTSMPDTPAADLIVPALAARIDAHLTELGGEFGPALPP
                     VDRRRVDAVAALLATDHPVPSKLWHAYEVLGAAAATRTEVTPVEGAVGASPAATAAWLA
                     HRRTPDRAARAYLDAVVARHGGPVPCCTPITTFERSWSLATLVRVGLPVTPSPGLVSEL
                     VAALGPDGAATGPGLPTDADTTSATLYALARLGHPVDPASLLRFDLGTHFCTWQGEDGH
                     SITTNAHVLEALGWHARNARDGAERYAPG"
     gene            13490..13993
                     /locus_tag="Jiend_RS31575"
                     /old_locus_tag="Jiend_47910"
     CDS             13490..13993
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="Jiend_RS31575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47910"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_249412213.1"
                     /sec_met_domain="T2TS (E-value: 1.2e-34, bitscore: 118.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLAGWLRDAQQPDGQWADRWHASPYYATCCAALALAGYAPAEV
                     ADAAVDRAADWVLATQRDDGGWGRWSTTTEETAYAVHVLLGAGRPIRPRVREAVLRALE
                     PLCAEPTEHPPLWHDKDLYTPILIVRAAVIAARRLAFAATETARGGASVPRQQGADQGM
                     ITTA"
     gene            14089..16671
                     /locus_tag="Jiend_RS23105"
                     /old_locus_tag="Jiend_47920"
     CDS             14089..16671
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734910.1"
                     /locus_tag="Jiend_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47920"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_111244425.1"
                     /transl_table=11
                     /translation="MGSRSSNLRTKVVALLASLVALWGFTAWVTVREGVNLVGVQALDV
                     RVFDPTEPLLLQLQTERRSSLVYLGRPEEAQRAELEQLRQRTDQLAAEFAESVDNWQVS
                     LLGSDDLHERVALLQQGLDALRDTRTAVDERNIGRGEAGTAFTELIESIYQVYDELGNL
                     DDDEVAENTTQLIRLNRARELLSQEDAMLAGVLAAGRITPAERAEFTRVVGARQFLAEQ
                     AIVRLPDADQQRYAQLIAAPSFQRLAELENEIMVGSGSSRPPFTGQDWAETTGPAMVEI
                     SDVVLAGGDDIVKSAVPVAVGVIVRLVLAAGLGLLAVIASVIVSITTARALVQQLQRLR
                     DAAFQLANDRLPSVVERLGQGEQVDVSKEAPPLQFGDDEIGQVGKAFNVVQETAIRTAV
                     EQAELRRAVRDVFLSLARRTQALVHRQLTLLDAMERREHDAEELEDLFRVDHLATRMRR
                     NAENLIVLSGSTPGRAWRRSVPMVDVIRGAVGEVEDYTRVQVLPISGVSLAGRAVGDVI
                     HLLAELIENGLSFSPPHTTVEVRGQLVANGFAIEIEDRGLGMTEEDLAAANYRIVDRSE
                     LNLADASRLGLYVVSRLTDRHGVRVQLKESAYGGTTAVVLIPSDLIIVDGAEPEAPVGT
                     RTEAPAVAAGPGPAARTERTTAPVALAAPAAPPAPPVPPAPRTADAGHDGVAERGQDVP
                     VELNLGPVDDTDGTGLPTRSRRRPGYSALDGPTIPIGLPVTSTSSTESVPRAPHRLIEN
                     TGGRPPIEPVPTAPEPGGVGVDSEPSRTESGLPVRIRQASLAPALRDEPEAAEEDDDVI
                     REPEQVRRMMSSYQTGTRRGRTDAARLLGGTGQAADGDDPDGADQQAT"
     gene            16751..17173
                     /locus_tag="Jiend_RS23110"
                     /old_locus_tag="Jiend_47930"
     CDS             16751..17173
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734909.1"
                     /locus_tag="Jiend_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47930"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_111244426.1"
                     /transl_table=11
                     /translation="MGQKTASSADLAWLLDDLVGRVKQAEHAVALSADGLLMASSQGLS
                     RDDGEHLAAMAAGIQSLARGAGKRFGGGQVQQTIIEMQSSFLFVTAAGRNACLAVLASE
                     DADVGLIAYEMAMLVTRVGKYVASPSRSADQTNGEK"
     gene            17179..17565
                     /locus_tag="Jiend_RS23115"
                     /old_locus_tag="Jiend_47940"
     CDS             17179..17565
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462630.1"
                     /locus_tag="Jiend_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47940"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_111244427.1"
                     /transl_table=11
                     /translation="MTVQGESAEHQWVDDHAGPVVRPYAVTGGRARPVTGTFDLISLVT
                     ATRKDVSPEIGIGPEHLAIVGLCQRMQSVAEIAAHLDLPVGTVRVLLGDLVARNLVQIR
                     EPQSTLGIPDHSIFEAVINGLRAL"
     gene            17546..18148
                     /locus_tag="Jiend_RS23120"
                     /old_locus_tag="Jiend_47950"
     CDS             17546..18148
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734907.1"
                     /locus_tag="Jiend_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47950"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_111244428.1"
                     /transl_table=11
                     /translation="MDYGHSERPSGAAALPTAIKILVAGGFGVGKTTMVGAVSETRPLR
                     TEEVLTESGVGIDDLSGVETKQTTTVAMDFGRITISDDLVLYLFGTPGQDRFWFVWDEL
                     ALGAIGAVVLADTRRLADCFPSIDYFEGRGTPFLVAVNCFEGARQYRLDEVQAALNLDP
                     EVPVLLCDARNRESAKEVLITLVEHAMKVRDARRRAE"
     gene            complement(18258..21113)
                     /locus_tag="Jiend_RS23125"
                     /old_locus_tag="Jiend_47960"
     CDS             complement(18258..21113)
                     /EC_number="4.2.1.3"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788270.1"
                     /locus_tag="Jiend_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47960"
                     /product="aconitate hydratase"
                     /protein_id="WP_111244429.1"
                     /transl_table=11
                     /translation="MKEYDVASLDTFGAKKQLRVGDASYEIFKISQVEGHDRLPYSLKI
                     LLENLLRTEDGANITAEHIRQLGAWDPTADPNVEIQFTPARVLMQDFTGVPCVVDLATM
                     REAVRELGGDPTKVNPLAPAELVIDHSVIADLFGREDAFERNVELEYERNKERYQFLRW
                     GQTAFNEFKVVPPGTGIVHQVNIEYLARTIMEREGQAYPDTVVGTDSHTTMVNGLGVLG
                     WGVGGIEAEAAMLGQPVSMLIPRVVGFKLSGEMPAGTTATDLVLTITEMLRKHGVVGKF
                     VEFYGPGVSAVPLANRATIGNMSPEYGSTVAIFPIDAETVRYLELTGRDPQQVALVEAY
                     AKEQGLWHDPAHEPSYSEQLELDLGTIEPSLAGPKRPQDRVPLGNAKTLFRAALTDYVA
                     ADETGGDPGRKPGVPQQEKPFGTAGHADEASAESFPASDPPANGVSDPADAPRDLVTAA
                     VGAGGRASSPIRVTGEDGVEYELDHGAVVIAAITSCTNTSNPQVMIGAALLARNAVDKG
                     LNRKPWVKTTLAPGSKVVMDYYERAGLTPYLEKLGFHLVGYGCTTCIGNSGPLPEEISA
                     AVNEADLAVVSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDIDLANEPIGED
                     SAGQPVFLRDIWPSTAEIQDVIASAIGATGFSAAYADVFAGDERWQSLPTPTGDTFAWD
                     GESTYVRKPPYFEGMRRLPAPVLDIGPARVLAKLGDSVTTDHISPAGSIKADSPAGEYL
                     AGHGVPRHEFNSYGSRRGNHEVMIRGTFANIRLRNQLVPGVEGGYTVNHLTGEQTSIYD
                     ASMAYQEAGVPLVILAGKEYGSGSSRDWAAKGTMLLGVRAVIAESYERIHRSNLIGMGV
                     LPLQYPTGENAESLGLTGTETFTITGVTGLNDGETPRTVRVTTDSGVEFDAVVRIDTPG
                     EADYYRHGGILQYVLRRMIAS"
     gene            21272..21634
                     /locus_tag="Jiend_RS23130"
                     /old_locus_tag="Jiend_47970"
     CDS             21272..21634
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015372.1"
                     /locus_tag="Jiend_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47970"
                     /product="VOC family protein"
                     /protein_id="WP_111244430.1"
                     /transl_table=11
                     /translation="MIHHVQLACPRGSEDASRAFYIGLLHLTEVPKPPALAARGGCWFT
                     GYGAELHLGVEDDFRPARKAHPALLRPDLDALADRLTAAGYPVAWGGDELPGLRRFHTE
                     DPHGNRLELLTPAATA"
     misc_feature    21280..21298
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.13"
                     /tool="antismash"
     gene            complement(21718..22374)
                     /locus_tag="Jiend_RS23135"
                     /old_locus_tag="Jiend_47980"
     CDS             complement(21718..22374)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013732340.1"
                     /locus_tag="Jiend_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_47980"
                     /product="C39 family peptidase"
                     /protein_id="WP_212808328.1"
                     /transl_table=11
                     /translation="MRTTILRKTALTIAAAAATAGGIAGPAVAAHAAPAPAAAQVQTDR
                     KPGGERQLDVRYEAQPNFYFCGPAAARNALSVQGKNIDVYDMAKRMGTTEAGTNSINDI
                     TPILNKETGKDVYRSVEIRDADAATKQVDKLRDDVVRTVDDGRAVVANIAGTTTDTDGT
                     THSFEGGHYISVTGYRDNGNQVKIADSADPNQAEYWITTDALANWIASRGYSATS"
     misc_feature    23402..23417
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.33"
                     /tool="antismash"
ORIGIN
        1 tcgctggagg aggtcgccgc cctcgaccgt acgatcaacg agccggtgct caagggcgtg
       61 tccttcaggg tcgaaccggg ccagatggtg gcccttgtcg gcccctccgg cgccggcaag
      121 tcgacgctct ccatactgat ctcgcgcatc tacgacgtga ccgaggggca ggtgctggtc
      181 ggcggggtgg acgtgcgcga cgccacgctc gactcgctgc gtgacgagat cggcgtggtc
      241 acccaggact cgcacctgtt ccacgagacc atcgcggaga acctgcgcta cgccaagccg
      301 gacgccaccg acgacgagtt gtgggcggcc ctcgccggtg cccaggtggc cgatctggtc
      361 cggtcgctgc ccgacgggct ggagaccacc gtcggcgagc ggggctaccg cttctccggc
      421 ggcgagaagc agcggatcgc catcgcccgg ctgctgctga aggcgccgtc gatcgtgatc
      481 ctcgacgagg cgaccgcgca cctcgactcg gagagcgagg cggcggtgca gcgggcgctg
      541 tcggtggcgt tgaccgggcg taccgcgttg gtgatcgcgc accggctctc caccgtccgg
      601 gatgccgacc agatcctggt gctggacggg ggacggatcg tcgagcgggg ccgccacgac
      661 gagttggtcg cggtgggtgg cctctacgcc gagctgtacc gcacccagtt cgcggtggtc
      721 gactcgccgt cgccgtacgc cgacgcgacc atgcccgagc cggtgatcat cccgacccgg
      781 gagtacgtcg cggacgaggc gttgccgcca gccgccgcca actgacccac ccacccgggg
      841 tcgatagctg tatactcgct tgcgagtaat cgcgtgcgag ggtggtgccg gtggccaagc
      901 gacgcaaggt cggcaacctc atggcgctgg ccgtgctctc cgtcctggcc caacggccga
      961 tgcatccgta cgagatcgcc acggcgctgc gtgggtgggg caaagaccag gacatgccga
     1021 tcaagtgggg ctcgctctac acggtcgtcg gcaacctcga tcggcacggg ttcatcgcgg
     1081 cggcggagag cgtacgcgcc gggcggcgtc ccgagcggac ggtgtaccgg atcaccgacg
     1141 ccggccgggc cgagcttgtc gactgggcac gtgaactgct cgccaccccg atgaccgagt
     1201 acccacgctt ccgggccggc ctgtcggtgc tggccgcgct gcatcccgac gaggccgccg
     1261 aactgctgcg acagcgactg catcagcttg tcgacaacct cgccacggcc cgcgccgcgc
     1321 tggccgggca cgccaccgag gtgccccggc tgttcctggt cgagtccgag tacgacctgg
     1381 tgctgggcga ggccgaggcg agctggatcc gcgctctgct cgccgagttc gacgcgggca
     1441 cctttcccgg cctcgaccag tggcggacgt tccacgagac cggcgagctg ccggccgagg
     1501 tggcagccct cgcggaacgc acaagcaccc cggagaggag cgacagcccc gacgacacct
     1561 cgtcatgacg aaccgacccc ggcgcggtgc gccaacaccg cgccggggtc atctcctcac
     1621 accgcacctg ggaaggcgct cggcacgagg cggcaaccaa cgagcatagc cgggttccct
     1681 cccagggcgg ttcgccatgc accgaaccga ttccctggga gggaacaatg accgacgtac
     1741 gcacagcgat catcatcggc ggcggcatcg ccggcccggt cgcggcgctc gcactgaagc
     1801 gggccggcat cacggcgacc gtgtacgaga cgtacccgaa caccgccggc ggcatcggcg
     1861 gcaccctggc gctggccccc aacggcgtgg cggcgctgcg gatcgtgggc gcggaccaac
     1921 tggtgatcga cctcgccacg ccgatccacc gcaccgtgct ggcgttcggt gcgaaccgca
     1981 tcgacctgcc cgtgctgccc ggcgtcccgc cgctgcgggt ggtgcaccgc aacgccctca
     2041 gcgggctgct gcaccagcgg gccgaagccg agggcgtgcc gatcgagtac ggccggcgcc
     2101 tggtcgacgc gcggcagacc cccaccggcg tcaccgccag gttcgccgac ggcagtaccg
     2161 ccagtgccga cctcctcatc ggcgccgacg gggtgcactc cacggtccgc gcgcttgtcg
     2221 atccgcaggc gccgggaccc cgctacaccg gcgtgctcgg gttcgagtct gtggcgtcgc
     2281 accccgtgga cgccgagccc ggcacgatga ccttcgcttt cggccggcgc ggctactacc
     2341 tctactggcc ggagccgggc ggcggcaccc ggtggggcgc gaacctgccc caacagcggc
     2401 cgctgagcct ggccgaggca cgggcgatcc ggcccgccga gtggtggaac cggctgcggg
     2461 agagctacgc cgacgacgat cccggtgccg cgctgatccg taccagcgac ccggacgagt
     2521 tgcaggtctc cggatcgctg cacatcatgc ctcgggtgcc gcactggcac cggggtcgga
     2581 tggtgcttgt cggcgacgcg gtgcacgcac cgtccaacag ctccgggcag ggggcgtcgc
     2641 tggccgtcga gagcgccgtg cagctcgccc gctgcctgcg tgacctgccg gacctgccgg
     2701 cggccctggc cgcgtacgag cggttgcggc gcgcccgggt ggagggcatc gccgcccgcg
     2761 cggcccggat caaccaggcc aaggccccgg gcccgatggg gcgggtggtc atgccgctga
     2821 tgatgcggtt gctgatgcgg gtcgcgatga agccggagcg gattctggga cccgagcagc
     2881 gctacacgat cgactgggcg gcgtcggccg cgaccgaaag gtcacccgcc tgacctcggc
     2941 ggatgcgtcc ggctcgcggg ctgctggccg gacgtgccgt cactgctgcc gagtggcctg
     3001 gcgtagttcg gcgaaggccg caccgagggt ctgcggtgtg tagtgcgcgt tcagtccgct
     3061 gggattgggc agcacccaca accgggcgtc ggccagcggc tccggctgcg ggccgaagcc
     3121 tgccttgggc cgggcgaacc cgatccggta cgcggtcacc ccgaccaccg ccacccagcg
     3181 gggccggtac cgggccacct tagcggtcaa cgtctgcgcg ccggccagga gttcggccgg
     3241 agtcagttcg tcggcgcggg cactggcccg gtcgaccatg ttggtgatgc cgagccccaa
     3301 ctcgggcaac tcaccctgct cgctggggtg catcagccgc ggcgtgaaac cgccccggtg
     3361 cagcgccggc cagaaccggt tgccggggcg ggcgaagtgc caaccggtcg ccgccgacca
     3421 caaccccggg ttgatcccga cgaagagcac gtccaacccg gtggcgatca cgtccggcag
     3481 ggtgcggtcg gcagccgcgg ccaactcctg ccgggtgaac cgagggctcg gctggctcgg
     3541 gcgacgcggt ggggatggcc ggcggagtgg atccgcttgg ggtcgcggat cgggtcggac
     3601 cggcggggcc ggctggctcg gacggcgctt cgcgtccggg tggtcggccg gccggtcgcc
     3661 gccgcccggc ccggcgctca caggccgcgc agcgcgccac cgtcgaccgg gatggtgacc
     3721 ccggtgaggt agctcgccgc aggcgagaga acgaacgcgg cgacccgacc gaattcggcc
     3781 ggttcgccga tgcggcgcag cgggatgcca gcttccgcgt cggcccgagc ccgctcggga
     3841 tcgccgctgg cagcgaagag ttcccggttg cggtcggtca tgatccgccc cgggagcagc
     3901 ccgacgactc gtacaccgcg cgggccgtac tcgtcggcga cgtccttggc gacgccggcc
     3961 agaccgggcc gcagcccgtt ggagatgccc aggccgggca ctgggctgcg ggccgaggtg
     4021 gagagcacca gcgcgatcgc gccgccgtcg ggcaacgcgg tggcgaccgt gcgcaccatg
     4081 cgtacgctgc ccaggaagac agtctcgaag gactgccgcc actgctgatc gtcgatcgag
     4141 gcggcgctgc cgggcggtgg gccgccgacc gagaccagcg cgccgtcgag ccgaccgaag
     4201 tgctgccggg cggcggcgac aagccgctcg ggcgtgtccg ggtcggccag gtcggcggtg
     4261 atcccgacgg cccgctccgg cccgccgagg tcggccaccg cagtcgccac cgcgtcgtcc
     4321 cgccgggcgg ccaggaccac ccgggcaccg tcggcgacca ggcactgtgc ggtggcgtgg
     4381 ccgaggccgc gagaggcgcc ggtgagtacg tacacccggt cggtcagtcc gagatccatg
     4441 ccatcgatct tgccgcaacc acgccgaccc ggcatccctc ccgccgccct accccggtcg
     4501 gcggccgccc ggcgcgccgg ggggtgtcaa gccgtacccg gctggcggcc tcccgccgcg
     4561 ccgaggggtg ttaagaaggg gccccttacc tgcaccaggc gttaataggg gtcccctcct
     4621 ttccgaaaag gccagcgacg gcgggggcgt gggggtggtg gccgtcgtag cggaagagct
     4681 tctcgcgggt ggccagttcc tcggcggcca gcggggcagc gccgcgcggg cctgtagcgc
     4741 gcgagccaga tcccagccgt cgcgcagacc gccgggattg gggcggccgg ctgcccactc
     4801 ggtgaaggtc gcgggccagc gcgggccgag gccggcggcg agcagcggcc agtgccgggc
     4861 cgcctcgcct gcgcgtttgc gcagcagagc ggcgcgggcg gcggccagcg gtcccggcgc
     4921 gaagcccggc ggcggcgtgg caccggtgac caacgccgcc accaactgtg cctgccggtg
     4981 tgccagtggg gtatcagcgg tcatcgggtc accagcggga agccggcggc gtgggccacg
     5041 gcgtccagtt cggcgcgcag gtcggtggcg ggagggtagt gcccgtcccg ttccagcagc
     5101 accgccggtg ggcggtgccg ggcgcacagc tcggtgagca ggtccagcac ctgtggcggg
     5161 accgggtcgg tgtgcgtgtc gtggtagtag ccgccctgct cggcaccgcc ggcgatgtgc
     5221 aggtacgcga tccggtccag cggcagcccg gccagcagcg cgagcgggtc gtcgccccgg
     5281 ttgcgggcgt tggcgtacac gttggcgatg tcgagcagca gcagcgcgcc ggtgcggtcc
     5341 aggatctcgg tgaggaacgc cgcctcgtcg agttcgtcgt ccggccagtc gaacagcgcc
     5401 gcgatcggtt ccagcgcgag cggcaccggc agctccgcct gcgtccgggc gacgttggcg
     5461 cagaccacgt cgacggcttc ccgggtgcgg ggcaacggca gcaggtgtcc ggcctccagg
     5521 ccgccggcgc ggacgaaggc gatgtgctcg ctgaccagtg gggccgcgac gagttcggcg
     5581 accgcggcca ggtgggccac ccgggccggt tcgaccggct gcgcgccgcc gagggagagg
     5641 cggaccccgt gcggtacgac ggcgacgccg cgttcccgaa gcgcggccaa tccgtgcggg
     5701 ggcgggccgg acctcggcag cgcttcggcg atcacctcga cgaagcgcag tccaggcagt
     5761 tcggcgacga atccgtcgat ctccggtcgc cagccgatgc ccaccccctc cgggccggtc
     5821 atccgccgca ccctccgccg ccacagccgc cgcccccgcc cccacagccg cctccgccgc
     5881 cgctgtcgcc gctgttgctt ccgcagccgc cggtgccggc ggcgctggca ccggagctgg
     5941 ccgcggccgc cttggtctgt agctcgatct cggcctgcgc ggcgaagacg ggatccagtg
     6001 cccagagcga cgcgacgccg aacaggcccg tcgccatcgc caccccgctg gcaccgtaga
     6061 gggagtacgc cgggttcgag gcgggggcga ggtgccggtg tcgggtacgc agggtccgca
     6121 acgcgttgtc ggccgcccgg gtccgccagg gcacccggac gaacagcaca gtggtgacca
     6181 ccgtcagtgc gcccacgatc agcacgaggt accagatagg acggtcgttg gccagccccg
     6241 ccacgatccg ggcgacgccg agcagcagca gcgcggagag cagcagcggg ccgagccgta
     6301 gggcggcccg tcgggtcggg ctgagcagca ggtcgtgccg gtccagcccg tcccgcagtt
     6361 cggtgagggc ccgctcgacc cattcggtgc ggcgcaggtc gcggccgtgg acgccctgcg
     6421 ccgcggcgta gtggatggct cggtcgagct ggctcgccgc gggtggcagc ggtccgtcga
     6481 cggtcagccg ccggtccggg gccaccccga tcacgccctg gctgcgcagc gtgccgagcg
     6541 aggtccagac cgccagttcc tcccggccgt tgaggtaggc gacctgctgt gggccgagct
     6601 ggtcggcggc gggggcggac cggcccgcca gcagggaccg acggtggatc agcacaccgg
     6661 ccacgagcag cagggccgcc gtcagatagc aggcgaggaa ggtgctgctg gggatgcccc
     6721 aggtgtcgaa gtccgcggcg agacgcgtca tgggctgctc ctgtcgcgcg aggggaaccg
     6781 cagcttcatt gtggagccgc gccgccagcc ggtggcaccc gcggtggccc agttaccgtg
     6841 ccgttacctg cgccggacgg cctcctcgac cagatcgagc accgggccga ggtcaccggc
     6901 cgggcgaccc atggccaggt gcagcaccag gccgtcgtag gcgagttcga ggaagcgggc
     6961 cagtacgtcg atcggtacgt cctcgcggag cacgccggcc tcccgctggc ggaccagccg
     7021 ttcccgggtc gcctcggcaa tggcagccga gcgctcggcc cagcgcttgg cgaaggccgg
     7081 gtcggtacgc aaccgccgtg acacctccag ttggctgccc aaccagccgg tggtgtccgg
     7141 ggatatcgcg cgggcgagca ggtcacgcat cacctggacc aggccgttgc gggcgacggt
     7201 ctccaccatc gtggccgcgt cgtcctcggc gacggcgagg aagagagagt ccttgtcccg
     7261 gaagtggtgg aagatcgcac cccgggacaa ccgggtcgcc tcctccagcc ggcgtacggt
     7321 ggcaccttcg tagccgtgcc gggcgaagca ggcccgggcg gcggcgagaa tctcctgccg
     7381 gcgggcgtcg agctggtcct gacttactct gggcacgtct cgatcgtgtc agccgatccc
     7441 tagtgaggca aaccgtacgt acggcttggg agtgtcggcc gggtgaatcg ccgctcacct
     7501 gccccgcgat gagcagtcga cccgaaggcg taacacccgg ccctgtcggc cgggtacccg
     7561 attcccgtaa ggtgcccgag tgccgctgct cctgctggat ctggacaaca ccctgctcga
     7621 tcgggccggg tcgttccgta cctgggcaga gcgcttcctg gacagcatcg gcgcgccgcc
     7681 gggggacatc gactggctgc tctccatcga cgccgacggt ctgaccgacc gctgggacgt
     7741 cgcggacgcc atccgggacc gctaccagct ccggatcccc tccatcgacc tggtcgagga
     7801 gctgcacgac ggcgtggtcg agttcacccg gctcgaccca cttgttgcct gtgcgttgcg
     7861 gatcgccgac gacgccggct ggatgccggt ggtggtgacc aacggcacgg tgcggctcca
     7921 ggacaccaag atccgtcgta ccgggctgga ccggtacatc gccgattggg tgatctccga
     7981 ggaggccggg gtcagcaagc ccaatccgcg gatcttcgcg ctggccgccc agcgggcgcg
     8041 gatgccgctg cgcggcgcct gggtgatcgg cgacgggccg gaggccgaca tcggcggcgc
     8101 caccgcggtc ggcctgccca gcatctggct gcatcgggga cggccgtgga cggacgcccg
     8161 gttcgcgccc accgcgacgg tggacaccgt gatcgccgcc atcgccacga tcatgggcgc
     8221 ttgaggccgg ttcggcgggc gccgcacggc gtaaatccgg ttgaccaggt cggggtgccc
     8281 ggcgagcatt gtcgcgcgca tcgtgcgtgc cgggcgtgcg cccggtcgag gagagggggt
     8341 cggtcatgac cgtcttcgca ggtcaactcc tgcctccagc cacctcgacc aagggacgac
     8401 agcgcagtgc gcgatcacga ctttccggcg tgggaacgcc gcaaccgcgg caagcgccgc
     8461 tttgatgacg acgaaccaca cctgctgaag cggagccggc cggccgagac cccggccgac
     8521 ccggaaccgg acccgggccc ggcctggtcc tcctgggacg acgcggtgca cggtccgcag
     8581 ccgcaccccg cctggctggt caccgaactg gcggcgcggg acaccgaact cggggtgctc
     8641 aagaccggca aggaggcgga ggttcatctg gtccgccgcg cggtcccgga cacggaccgc
     8701 tcctgcctgc tggcggccaa gcgttaccgc gatccccggc atcggctctt tcaccgcgac
     8761 gccggctatc tggagggacg gcgggtccgc cggtcccggg agatgcgggc catggtcggc
     8821 cggaccgcgt tcggccggca gatgatcgcc ggccagtggg cagcggccga attcggcgcg
     8881 ctggcccggc tctgggagat cggcagccgg tacggcacga tcaacgtccc gtacccggtg
     8941 cagttgcgcg gcaccgagct gatgctggag ttcctcggcg atccggacga ggggcgcgcc
     9001 gcgccccggc tggccgagct gcgtccggac cccaccgagc tgcgtgacct gtgggcgcag
     9061 ttggtggacg cgcttgtggt cctggcccgc gccgggtacg cgcacggtga cctgtccccg
     9121 tacaacctgc tggtgtgcgc ggggcggttg gtgctcatcg acctgccgca ggtcgtggac
     9181 gtggtggcga atccgcaggg gcgcgagttc ctggcccgcg acgtccggat cgtggccacc
     9241 tggttcgtgg cccgtggcct gccgccgggc ctggccgacc cgagcgcgtt gaccgagctg
     9301 ctctcgcgcg aggccggcct gcgctgactg agctgctctc ccgcgaggcc ggtctgcgct
     9361 gacgatgggc tccgggcggc gaatgccgtc gcccggagcc cgttcacgcg atccgtcacg
     9421 cttggcgggc tacctgatca ctgtaggtat cgctcgacct ctggcaccgg gcgagcgccc
     9481 tgcgcgtcgg ggtcgccgtg ggcctggcga gcggcacggc ggcgacggag cagatcccag
     9541 cactggtcaa gggactcctc cagctcgcgc agccgggtgc gggcctcgtc atcggtgccg
     9601 gcctcgtgtg cctgcgccgt ggcgcgcagc cggtgttcct cgtcgaccag atcagagatc
     9661 cggctcagga tggtcttgtc gtccatgcct ctgagcctgg cacagcgagg cgggtggcgc
     9721 ccggattcct tccggcgcgg ccacctgggc gtggtgggcc gagtgtcgtc ggcgcggccc
     9781 gccggctcct ccgacatgac caagatcacc gaggttgcgg aggtcgatgc cggccctgac
     9841 ccgagtcgat cgaccactta cctctcgatt tcggcattga ccagcgaaaa cgcggcggcg
     9901 agcgagaccc gcgggcccgt cggtgggcaa tttgtccact gtggcattag tcgtcgaacg
     9961 tccgatctct gctgtggaca gcgggaatgt cgaccatgaa gatttctcgc tacgcgacta
    10021 gtaaggagtg ccatcgcaat ggcatgctca tcgcgaccac ggcaattcga agagtgatgc
    10081 cccgtacccc tggggcctgt tgcaggcggg agccgaccac gccatgtccg tccacaccag
    10141 acgagcggga tccatacccc tgcggcacgt ggtgccgagc ctgatgcgtg acccggcccg
    10201 tgcgcttgtc gagttcggcg accggtccgg gggcgaggtg gtcaagctca acctcggttc
    10261 gttccgcccg tacctcatca cccatcccga ccaccttcag cgggtgctgc gggagaagtc
    10321 cggcaactac gtccgggccg gcgacggcct gcagtggcgt ccactgaagc ggttgttcgg
    10381 cgagggcatc ctcagcgacg gagaatactg gaccaacagc cggcagatcc tccagccgct
    10441 gttcacggcc cggcgcatcg acgggctcgt cgaccgcctc gcggtggcga tcgaggaggc
    10501 catcgacgag ttggcggagc cggcgcggac cggtcagccg gtggacatgg gcaccgtgca
    10561 ggccgagatc gtctgttcgg cgatcatgcg ggtcttcttc gacaacaaga tcaccgtgcc
    10621 ggacgcaatg cggatcatgg aagcgcagga cgccatcgcc tggtcggtga tgccccggat
    10681 catggtgccg tgggcgccga actacgcgcc gatgccgggc gaccggacgt tccggcgcgc
    10741 cgtgcagctc atcgacgacc tgctgctgcc caccgtgcgg gcggcgcgcg acaccgccca
    10801 cgagggcgcc gacgacatca tctccaccct gtggcggggg cgcaccgagg acggcggccg
    10861 gctggacgag cgtcaggtcc gcaacgacac ggtggcgatg gtggccacca ccaccgagac
    10921 cacgatcagc gtgctcacct ggctctggcc gcacatcgag caggacccga cggtcgccac
    10981 ccggctctac gaggaactcg accgggtggt gggcgaccag ccggtccgcc gcgaacacct
    11041 gcgcgagctg cgctacctgc ggcaggtcct cgacgaactg ctgcggctct atccgatcgg
    11101 ctggctcttc ccgcgtcgag cggtcgagga ggacgtcatc ggcggcgtcc ggatcccggc
    11161 cggcgccact ctcgtggtca gcccgctgat cacccagcgg atgtcgatgt tctgggaccg
    11221 gcccgaggtc ttcgatcccg accggttcag cccggaggcg tcccgcggcc gacccaagta
    11281 cgcgcacttc ccgttcggcg gcggcccgca ccagtgcctc ggcatgcacc tgttctatct
    11341 ggaggccacc ctgatcgtgg ccaccctgct gagccggttc cggttccggt tgcgccgttc
    11401 gggcgtgccc ggcatcaagg tggcggccgc gttgcgcccg ctcgaccggg tcgaggtgac
    11461 cctgcgaccg gtgcagggtg tggcggcgtg agcgcccgga ccgagccgcc ggacgccggc
    11521 ggagaccaac tgctgatcgc cgccgaacag ggccgcatct gtgccctcgc cgcacagggc
    11581 cagcgtgacc tggcgaaggt cgcggcgtcg tacccggatc tgtttcccgc caagccgttc
    11641 gacgcggcgc tcttcggcaa cgtggcgatg gccatcgcct tcggcgcgcc ctggtgcgac
    11701 ccggcccaac tgcggatcac caaccgtgtc gtgctctggg gcttcgccgt cgactggctg
    11761 atcgaccacg aggcacgatc gcgcgacgag atcgaccggc tgaccgcacg ctgcctcgcc
    11821 gtggccgatg gcgggagtcc ggaggagggc gacgccctgg gcgccttcct cgccgagctg
    11881 cgggacgagc tcgcggccgt gccggccttc gccgaacacc ggcaccgctg gcgcgacgag
    11941 atccgtacgg tgctggttgc catgggccgc gagtgggact ggaagcagca gccggaccag
    12001 ctgcccagct tcgcggaata cctggacaac gccgccaacc tggcctgcac ggtggtcaac
    12061 gtggtgcact ggatccacac cgacgacccg gcgacgctga aacacctgga cgcgttgctc
    12121 gccgccagcg accaggtcca gcgcatcctt cgactggtca acgacctcgg cacgtacgaa
    12181 cgtgatgtgc gctggggcga cctcaacgcc ttgctgctgg tgcccagggc cgaggtcgag
    12241 cagcggatca tcgagctggt ggccgaggcc cgcgcgatgc tggagccgct gcgcgacagc
    12301 gttccggtgc ccgccgacta cctggcccgg cagatcggtt tcagcagcgg gttctaccgt
    12361 tccaccgact tctggggcgt gtcgtgacga ccgtggcacc cgccgtcggc gcggagaccg
    12421 ggcccagtgt gaccgccgcc gcccgcgatc tggtcgccct gctggaacgc gaaccggccg
    12481 ggcaggtgag caactccgtc tacgagaccg gacggctcgt cgccgacgcc ccgtggctgg
    12541 acgggcacgg gcgacggctg gcctacctgc ttgcgcagca gagtgccgac ggcagttggg
    12601 gcccggcggg cgggtacgcc ctggtgccca cggccagcgc ggtgcaggga ctgctcgccg
    12661 aactggtccg ggctgatccg gccggcactg cggcccgagc cgaactcgcc gccgccaccg
    12721 cccggggcct ggccgcgctg gctcgacggt tggccgacgg cacgtccatg ccggacaccc
    12781 cggcggcgga tctgatcgtg ccggccctgg ccgcgcggat cgacgcgcac ctgaccgagc
    12841 tgggtggcga gttcgggccg gcactgcccc cggtggaccg acgccgggtc gacgcggtcg
    12901 ccgcgctgct cgccaccgac cacccggtgc ccagcaaact ctggcacgcc tacgaggtgc
    12961 tcggcgcggc cgccgccacg cgtaccgaag tcaccccggt cgagggtgcg gtgggcgcct
    13021 cgccggcggc caccgcggcc tggctcgccc accggcgtac gccggaccgc gccgcccggg
    13081 cctacctcga cgccgtcgtg gcccggcacg gtgggccggt gccgtgctgc acgccgatca
    13141 cgactttcga acggtcctgg tcgctggcca cgctcgtccg ggtggggctg ccggtgacgc
    13201 cgtcgccggg gctggtcagt gagctggtcg ccgccctcgg ccccgacggc gcggccaccg
    13261 gccccggtct gccgaccgac gccgacacca cctccgccac cctgtacgcc ctcgcccggc
    13321 tgggacaccc ggtggacccg gcgagcctgc tccgtttcga cctgggcacg cacttctgca
    13381 cctggcaggg ggaggacgga cactcgatca ccacgaacgc gcacgtgctg gaggcgttgg
    13441 gctggcacgc caggaacgcg cgggacggtg ccgagcggta cgcccccggg tgacccggct
    13501 cgccggatgg ctgcgtgacg cacaacaacc ggacgggcag tgggccgacc gatggcacgc
    13561 ctcgccttac tacgccacct gttgcgcggc gctggccctg gccggctacg caccggccga
    13621 ggtggccgac gcggccgtcg accgggcggc ggactgggtg ttggccaccc aacgtgacga
    13681 cggtggctgg ggacgctggt cgaccaccac ggaggagacg gcgtacgcgg tgcacgtgct
    13741 gctcggcgca gggcggccga tccgaccccg ggtgcgggag gcggtcctca gggccctcga
    13801 accactgtgt gccgaaccga ccgaacaccc accactgtgg cacgacaagg acctctacac
    13861 gccgatactc atcgtccgtg cggcggtgat cgcggcccgg cgactggcgt tcgcggcgac
    13921 cgagacggcg cgtggcggcg catcagtccc acgccagcag ggggccgacc agggcatgat
    13981 cacgaccgct tgagttgctg cggtgacgct gttagcgtgc gccggggtcg gtgcgcgcga
    14041 cacgccgctg actgacagat caactcgctc agggccaggg acggtgtaat gggttcccgc
    14101 agttcgaatc tgcgtaccaa ggtcgtggct ctgctggctt cgctggtggc gctctggggc
    14161 ttcacggcct gggtcaccgt ccgggagggt gtgaacctgg tcggcgtgca ggcgctcgac
    14221 gtgcgggtgt tcgatcccac cgagccgctg ctgctccagc tccagacgga acggcgcagc
    14281 tcgctcgtct atctcggccg gcccgaggag gcccagcggg ccgagctgga gcagctgcgt
    14341 cagcgtacgg accagctggc cgcggagttc gccgaatcgg tggacaactg gcaggtgagc
    14401 ctgctcggca gcgacgacct gcacgaacgc gtcgccctgc tgcagcaggg gctggacgcg
    14461 ctgcgggaca cccgcaccgc cgtcgacgag cgcaacatcg gccgcggcga ggccggcacg
    14521 gcgttcaccg agctgatcga gtcgatctac caggtgtacg acgaactcgg caacctcgac
    14581 gacgacgagg tcgccgagaa caccacccag ctgatccggc tcaaccgggc tcgcgagctg
    14641 ctgtcccagg aggacgcgat gctcgccggt gtgctggccg ccggccggat cacccccgcc
    14701 gagcgggccg agttcacccg ggtggtgggt gcccgccagt tcctcgcgga gcaggcgatc
    14761 gtccggcttc ccgacgccga tcagcaacgc tacgcgcagc tgatcgccgc tccgagcttc
    14821 cagcggctgg ccgagctgga aaacgagatc atggtcggct ccggcagctc ccggccgccc
    14881 ttcaccggcc aggactgggc ggagaccacg ggcccggcga tggtcgagat cagcgacgtg
    14941 gtgctggccg gcggtgacga catcgtcaag agcgccgtcc cggtcgcggt cggggtcatc
    15001 gtccggctgg tgctcgccgc cggtctcggc ctgctcgcgg tcatcgcctc ggtgatcgtc
    15061 tcgatcacca ccgcgcgggc cctggtccag cagttgcagc ggctgcgcga cgccgccttc
    15121 cagctcgcca acgaccggct gccgagcgtg gtggagcgac tcggtcaagg cgagcaggtg
    15181 gatgtcagca aggaggcccc accgctccag ttcggcgacg acgagatcgg ccaggtgggt
    15241 aaggccttca acgtcgtgca ggagaccgcg atccggaccg ctgtcgagca ggccgaactg
    15301 cgtcgggcgg tgcgtgacgt cttcctcagc ctggcccgac gtacccaggc cctggtgcat
    15361 cgccagctca ccctgctgga cgcgatggag cggcgcgagc acgacgcgga ggaactggag
    15421 gacctgttcc gcgtcgacca cctcgccacc cggatgcggc gcaacgccga gaacctgatc
    15481 gtgctctccg gctccacccc cggtcgggcc tggcggcgca gcgtgccgat ggtggacgtg
    15541 atccggggcg cggtcggcga ggtcgaggac tacacccggg tccaggtgct gccgatcagc
    15601 ggtgtgtcgc tggccggccg tgcggtcggt gacgtcatcc acctgctcgc cgagctgatc
    15661 gagaacgggc tctcgttctc cccgccgcac accacggtgg aggtacgcgg gcaactggtc
    15721 gccaacggct tcgccatcga gatcgaggac cgcggcctcg ggatgaccga ggaagacctg
    15781 gccgcggcca actaccgcat cgtggaccgc tccgagctga acctcgccga cgcgtcccgg
    15841 ctcggcctgt acgtggtgag ccggctgacc gaccggcacg gggtgcgggt gcagctcaag
    15901 gagtccgcgt acggcggcac cactgccgtg gtgctgatcc cgagcgatct gatcatcgtg
    15961 gacggtgccg agcccgaggc gcccgtcggc acccggaccg aggcgccggc cgtggccgcc
    16021 ggtccggggc cggctgccag gaccgagcgg acgaccgcgc cggtggccct cgccgcgccg
    16081 gcggcaccgc ccgcaccgcc cgtaccgccc gcaccccgca ccgccgacgc cgggcacgac
    16141 ggcgtggccg aacgcggtca ggacgtaccg gtcgagctca acctcgggcc ggtggacgac
    16201 accgacggca ccgggctgcc gacccggtca cggcgccggc ccggctactc cgcactggac
    16261 gggccgacca ttccgatcgg gctccccgtc acctcgacgt cgagcaccga gagcgtccca
    16321 cgggcacccc accggctgat cgagaacacc ggcggtcgtc cgccgatcga accggtgccc
    16381 acggcacccg agccgggcgg tgtcggtgtg gacagcgagc cgagtcgcac cgagtcgggc
    16441 cttccggttc ggatccggca ggccagcctc gcgcccgcgt tgcgggacga accggaggcg
    16501 gcggaggagg acgacgacgt gatccgcgaa cccgaacagg tgcggcgcat gatgagttcg
    16561 taccagaccg gcaccaggcg cgggcgcacc gacgccgccc ggttgctcgg cggtaccggt
    16621 caggcagccg acggggacga tcccgacggc gccgaccaac aagcgacctg agccgcggtc
    16681 gggcggaccg cacgaccgcc ggccaggcac agatgagcac ggcgagagcc gaggagaaga
    16741 ggacgacgaa gtggggcaga agacggcttc gagtgccgac ctggcgtggt tgctggatga
    16801 cctggtcggc cgggtcaagc aggccgagca cgcggttgcg ctgtccgccg acggtctgtt
    16861 gatggcctcc tcgcaggggc tcagccgtga cgacggcgag catctggcgg cgatggcggc
    16921 tggcatccag agcctggccc ggggcgcggg caagcggttc ggcggtgggc aggtgcagca
    16981 gacaatcatc gagatgcagt cgtccttcct gttcgtcaca gccgccggtc gcaacgcctg
    17041 cctcgcggtt ctggccagtg aggacgccga tgtgggactg atcgcgtacg agatggccat
    17101 gctggtcacc cgggtcggca agtacgtcgc ctcgcccagt cgatcagcgg accagacaaa
    17161 cggggagaag tagcacgcat gacggtgcag ggagaatctg ccgaacatca gtgggttgac
    17221 gaccatgctg gcccggtggt ccgtccgtac gcggtgaccg gcggccgggc ccggccggtc
    17281 accggcacgt tcgacctgat ctccctggtg acggcgaccc gcaaggacgt gtctccggag
    17341 atcggtatcg gcccggagca tctggcgatc gtcggactgt gccagcggat gcagtccgtc
    17401 gccgagatcg cggcacacct ggacctgccg gtcggcaccg tgcgggtcct gctcggtgat
    17461 ctggtggcgc gcaacctggt acagatccgg gagccgcaga gcaccctcgg cattcccgac
    17521 cacagcatct tcgaggcggt tatcaatgga ctacgggcac tctgagcggc cgtcgggcgc
    17581 agccgcactg cccacggcga tcaagattct ggtcgcgggc ggcttcgggg tgggcaagac
    17641 gacgatggtc ggcgcggtca gcgagacacg tccgctgcgc accgaggagg tgctgaccga
    17701 gtcgggcgtc ggcatcgacg acctgtccgg ggtggagacc aagcagacca ccaccgtggc
    17761 gatggacttc ggtcgcatca ccatcagcga cgatctggtg ctgtatctct tcgggacccc
    17821 ggggcaggac cggttctggt tcgtctggga cgagttggcc ctcggcgcga tcggcgccgt
    17881 ggtgttggcc gacactcgcc ggctggccga ctgcttcccc tcgatcgact acttcgaggg
    17941 acggggcacc ccgttcctgg tggcggtgaa ctgcttcgag ggggcccggc agtaccggct
    18001 cgacgaggtg caggccgcac tgaacctcga ccccgaggtg ccggtgctgc tctgcgacgc
    18061 ccgcaaccgc gagtcggcca aggaggtgct gatcaccctg gtcgagcacg ccatgaaggt
    18121 ccgggacgcg cgccgccggg ccgagtgacg accgggggtc gccggccggg tccgccgccg
    18181 gtcgcgcccc agcacccctg ccgtacgacg aagggctcct tcccacgccg ggaaggagcc
    18241 cttcgctgtc gggtacgtca gctggcgatc atgcgccgca gcacgtactg gaggatgccg
    18301 ccgtggcggt agtagtcggc ctcacccggg gtgtcgatcc gcaccaccgc gtcgaactcg
    18361 accccgctgt cggtggtcac ccgcaccgtg cgcggggtct cgccgtcgtt gagcccggtc
    18421 acgccggtga tggtgaacgt ctcggtgccg gtcagcccca acgactcggc gttctcgccg
    18481 gtcgggtact gaagcggcag cacgcccatg ccgatcaggt tggagcggtg gatccgctcg
    18541 tacgactcgg cgatgaccgc cctgaccccc agcagcatgg tccccttggc cgcccagtcg
    18601 cgcgacgagc cggaaccgta ctccttgccg gccaggatca ccagcgggac acccgcctcc
    18661 tggtaagcca tcgaggcgtc gtagatcgag gtctgctcac cggtgaggtg gttgaccgtg
    18721 tagccaccct cgacgccggg caccagctgg ttacgcaacc ggatgttggc gaacgtgccg
    18781 cggatcatca cctcgtggtt accccggcgg gagccgtacg agttgaactc gtgccgtggc
    18841 acaccgtgtc cggcgaggta ctcaccggcc ggggagtcgg ccttgatcga gccggccggg
    18901 gagatgtggt cggtggtcac cgagtcgccc agcttggcca gcaccctagc cggaccgatg
    18961 tcgaggacag gcgccggcag gcgccgcatg ccctcgaagt acgggggctt gcggacgtag
    19021 gtggactcgc cgtcccaggc gaaggtgtcc ccggtcggcg tcggcaggga ctgccagcgc
    19081 tcgtcaccgg cgaagacgtc ggcgtacgcg gcactgaagc cggtggcgcc gatcgccgag
    19141 gcgatgacgt cctggatctc ggcggtgctc ggccagatgt cgcgcaggaa gaccggctgg
    19201 cccgcgctgt cctcaccgat cggctcgttg gccaggtcga tgtccatcgt gccggcgagg
    19261 gcgtacgcca ccaccagcgg cggcgaggcc aggtagttca tcttgacgtc ggggttgatt
    19321 cggccctcga agttgcggtt gccggagagc accgacacca cggcgaggtc ggcctcgttc
    19381 accgccgccg agatctcctc cggcagcggg ccggagttgc cgatgcaggt ggtgcagccg
    19441 tagccgacca ggtggaagcc gagcttctcc aggtagggcg tgaggccggc ccgctcgtag
    19501 tagtccatga ccaccttcga gccgggggcc agggtggtct tcacccacgg cttgcggttc
    19561 agccccttgt ccaccgcgtt gcgggcgagc agcgccgcac cgatcatgac ctgcgggttg
    19621 gaggtgttgg tgcaggaggt gatggcggcg atcaccaccg cgccgtggtc cagctcgtac
    19681 tcgacgccgt cttcgccggt gacccggatc gggctgctgg cccgcccgcc ggcaccgacg
    19741 gccgcggtga ccaggtcgcg cggggcgtcg gcggggtcgc tcaccccgtt ggccggcggg
    19801 tcgctggccg ggaacgactc ggcgctggcc tcgtcggcgt ggccggcggt gccgaacggc
    19861 ttctcctgct gcggcacgcc gggcttgcgg cccgggtcgc cgccggtctc gtcggcggcc
    19921 acgtagtcgg tgagtgcggc gcggaacagc gtcttggcgt tgcccagcgg cacccggtcc
    19981 tgcgggcgct tcggcccggc gagcgagggc tcgatggtgc ccaggtccag ttccagctgc
    20041 tcggagtagg acggctcgtg ggccgggtcg tgccagagtc cttgttcttt cgcatacgcc
    20101 tcgaccagcg cgacctgctg cgggtcccgg ccggtcagct ccaggtagcg cacggtctcg
    20161 gcgtcgatcg ggaagatcgc cacggtggag ccgtactccg gggacatgtt gccgatggtg
    20221 gcccggttgg ccagcggcac ggcgctcaca ccggggccgt agaactcgac gaacttgccg
    20281 accacgccgt gcttacgcag catctcggtg atggtgagca ccaggtcggt ggcggtggtg
    20341 ccggccggca tctcaccgga gagcttgaag cccaccacgc gggggatcag catgctgacc
    20401 ggctgaccca gcatggccgc ctcggcctcg atgccgccga cgccccaacc cagcacgccc
    20461 aggccgttga ccatcgtggt gtgcgagtcg gtgccgacga ccgtgtccgg gtacgcctgt
    20521 ccttcgcgct ccatgatcgt acgggccagg tactcgatgt tgacctggtg cacgatgccg
    20581 gtgccgggcg ggaccacctt gaattcgttg aaggcggtct ggccccagcg caggaactgg
    20641 taacgctcct tgttgcgctc gtactccagc tcgacgttgc gctcgaaggc gtcctcgcgg
    20701 ccgaacaggt cggcgatgac cgagtggtcg atgaccagct cggcgggggc gagcgggttc
    20761 accttggtcg ggtcaccgcc cagctcgcgg acggcctcgc gcatggtggc caggtcgacc
    20821 acgcacggta cgccggtgaa gtcctgcatc agcacccgcg ccggggtgaa ctggatttcg
    20881 acattggggt ccgcggtcgg atcccaggca ccgagctggc ggatgtgttc ggcggtgatg
    20941 ttcgcgccgt cctcggtccg cagcaggttc tccagcagga tcttcaggct gtaggggagc
    21001 cggtcgtggc cctccacctg gctgatcttg aaaatctcgt agctcgcgtc tccgacgcgc
    21061 agctgcttct tcgcaccgaa ggtgtcgagg ctcgccacgt cgtactcctt cacaccagcg
    21121 accgtgagta gtcctgagca gtctgtcgca ccggccggaa ggccgccgag cttaggcgac
    21181 acttaccgcc gattcgcgct gtcaacaaaa ccgtacgtcc gtcttgctat taggtcaacc
    21241 cgctgccatc gtgtggacgg gaggtgcatc catgatccat cacgttcagc tcgcctgccc
    21301 acggggctcc gaggacgcct cgcgggcctt ctacatcggc ctgctccacc tgaccgaggt
    21361 gcccaagccg ccggcactcg cggcccgcgg cggttgctgg ttcaccgggt acggtgccga
    21421 actgcacctc ggcgtcgagg acgacttccg gcccgcccgc aaggcgcatc ccgccctgct
    21481 ccggcccgac ctggacgccc tcgccgaccg gctgaccgcc gccggatacc ccgtcgcctg
    21541 gggcggcgac gagttgccgg ggctgcgccg cttccacacc gaggacccgc acggcaaccg
    21601 cctggagctc ctcacccccg ccgcgaccgc ttgacgccgc atcttcactg acgttgtcgt
    21661 ggtgtcgaca agggccgacc tccggggtgg gaggtcggcc cttgtggtgt cgcggggtca
    21721 gctggtggcg ctgtagccgc ggctggcgat ccagttggcg agtgcgtcgg tggtgatcca
    21781 gtactcggcc tggttggggt cggcggagtc ggcgatcttc acctggttgc cgttgtcgcg
    21841 gtagccggtg acgctgatgt agtggccgcc ttcgaagctg tgggtggtgc cgtcggtgtc
    21901 ggtggtggtg ccggcgatgt tggcgaccac ggcgcggccg tcgtcgacgg tgcgcacgac
    21961 gtcgtcgcgg agcttgtcaa cctgcttggt ggcggcgtcg gcgtcgcgga tctccacgga
    22021 gcggtagacg tccttacccg tctccttgtt caggatgggg gtgatgtcgt tgatggagtt
    22081 ggtgccggct tcggtggtgc ccatgcgctt ggccatgtcg tacacgtcga tgttcttgcc
    22141 ctgcacgctc agcgcgttac gggcggcggc ggggccgcag aagtagaagt tgggttgggc
    22201 ttcgtagcgc acgtcgagtt ggcgttcgcc gccgggcttg cggtcggtct gcacctgggc
    22261 ggcggccggt gcgggggcgg cgtgggcggc gacggcgggg ccggcgatgc cgccggcggt
    22321 ggcggcggct gcggcgatgg tgagggcggt cttgcgcagg atggtggtac gcatgatggt
    22381 ctcaccttcc gttcggggga tgacgcagcg gtggatcgac ccagatgggg atcgtgctgc
    22441 gtggggggag ataagggaga cgtccggcgg gggtgctcgg gcgtccgggg ggatgtaacg
    22501 accccgggcg gtcaggcatt ccgggggttc ggggtgccgg gggatgtaac gacccgggcc
    22561 ggtcaggcat tccggggttc ggggtgccgt ggcaggtccc cggggggtgc gggtcggggg
    22621 agtgcccgcg gtcagtcatg tacaacgccg cccgcctgcc caccattccg ccggccccgc
    22681 acccacgccc cggacatata cgacatgaag cccaggcggt gtgaatcttg gtcgcaaact
    22741 gcccctatgg gggcattttc gcaccaagat ccggtgtggc cccggggcag gctggtgggt
    22801 tattggggtg cgggagggga aggcgtgggc agcggaaggg gcgacctggg ggaggacgtc
    22861 gtgtcgcagc acatcaggcc cgccgccagc cacgagcgcc tggccccggt ggccggagcg
    22921 ccgttgtggt gtgacgcgcg agattacgga cttcagggcg atggggtgac gaacgatcag
    22981 cccgcgctct ccgccctggt ggaccggctc ggcgaggggt acgccgccga cgggcgggcc
    23041 cgggtcatct actgcccgcc ggggatctac tcgatccggg acgcgggcac ggtctggcgc
    23101 agcggagtgt ccctgctcgg cgcgggctcg ggagcgaccc ggtttctgct gagcaacgag
    23161 ggcaaccggg ccgagccgac gccgctcgcc ttctggacca ccctgcagca cggtgccgac
    23221 cgcgatcgtc acatcgccga ctgcaccttc gccgacttcg agatcgacgg ttcgggcgtg
    23281 gccctggccc agtacaacta tctcgccaag gggctggggc ttcagtacgt ggtccggggc
    23341 gtcttccgaa acctttacat ccaccacacc ggcgccaccg ggttgggctg tgacttcctt
    23401 caggactgcc tggtcgacgg ggtggtcgtg gtgggctgtg gccggctgga caacggcgag
    23461 cagatgggcg gcgccgggat cggcatcggt gtggggggtt ggggggcggt ggagcgttgc
    23521 accatcacca actgcaccac gctcggcaac ggcaccaatg gaatcttcct ggagttgcag
    23581 aagccgtact gggagccgcc gcgtggatac cgcatcatcg gctgccacag ccaggccaac
    23641 cggttcggca tctccgactg gggagccgac gggctgatcg tctccggatg cacgatcacc
    23701 ggcaacctgg aggccggttt cgacatctcc ggcaacggca ccgcgggagt cgcgggccgg
    23761 ggcggcatcc tcaccgactg cgtgatcgac cgcaacgtcc gggacggcat cagcgtgggc
    23821 aacacgcccg gggcgtacac catccggggc aaccggatca gtggcaacgg tggacacggc
    23881 taccaccagc acgacctggg tgacggttac cagggcccgg cggcggagat cgtcatcgac
    23941 ggaaacgact tctgggacaa cggcttggac gcgatccggg tcgaccggcc gat
//
