LOCUS       NZ_AP023358            21083 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Micromonospora endophytica strain NBRC 109090 chromosome, complete
            genome.
ACCESSION   NZ_AP023358
VERSION     NZ_AP023358.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora endophytica
  ORGANISM  Micromonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Jishengella endophytica NBRC 109090
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6586761)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 293x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326245.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 14:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,248
            CDSs (total)                      :: 6,184
            Genes (coding)                    :: 5,715
            CDSs (with protein)               :: 5,715
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 469
            CDSs (without protein)            :: 469
            Pseudo Genes (ambiguous residues) :: 0 of 469
            Pseudo Genes (frameshifted)       :: 323 of 469
            Pseudo Genes (incomplete)         :: 166 of 469
            Pseudo Genes (internal stop)      :: 12 of 469
            Pseudo Genes (multiple problems)  :: 30 of 469
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:19:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4656537
            Orig. end                         :: 4677620
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023358.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11083)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    330..345
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(558..1229)
                     /locus_tag="Jiend_RS21905"
                     /old_locus_tag="Jiend_45440"
     CDS             complement(558..1229)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463103.1"
                     /locus_tag="Jiend_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45440"
                     /product="NADPH-dependent F420 reductase"
                     /protein_id="WP_111242023.1"
                     /transl_table=11
                     /translation="MTTVGFIGSGHIGGTVARLAVNAGYDVVLSNSRGPETLADLVDEL
                     GPQASAGTVEAAARAGDLVVVTIPLKAYRSVPAAPLAGKLVIDTNNYYPERDGQFPELD
                     DGATTSSELLQRQLPEARVVKAFNNIFFKHLLALARPTGAADRSALPIAGDDPQAKSAA
                     TAFLDRIGYDAFDAGALADSWRFQPDTPAYGVIYSADPTNWEQAAPGDIGKLRAALAKA
                     G"
     misc_feature    complement(1305..1318)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    1380..1394
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.1"
                     /tool="antismash"
     gene            1421..3037
                     /locus_tag="Jiend_RS21910"
                     /old_locus_tag="Jiend_45450"
     CDS             1421..3037
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018807938.1"
                     /locus_tag="Jiend_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45450"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_119663692.1"
                     /transl_table=11
                     /translation="MKRSLRRALWLGAVVAVTVATVPMASAFGAGNVTASFTRASDWGT
                     GHETKVTITNGSSASVSTWRIEFELPAGTTISSSWDADVTRDGNRYVAVKKSWAGALAP
                     GDSFSWGYNGTGGYRAPLNCTVNGAACGGGTTPPTTTPTTTPPTTTPPTTTPPTTTPPT
                     TPPSGDRKVVGYFAQWGVYARNYHVKNIHTSGSAAKLTHILYAFGNTTGGRCTIGDSYA
                     DYEKAYTAAESVDGVADTWDQPLRGSFNQLRKLKKMYPHLKVIWSFGGWTWSGGFTQAA
                     QNPAAFAESCYNLVEDPRWADVFDGIDIDWEYPNACGLTCDASGPNAFKNVASALRSRF
                     GSGNLVTAAITADGSNGGKIDATDYAGAATHLNWIMPMTYDYFGAFAPQGPTAPHSSLY
                     SYTGIPQQGFWSDAAIQKLKSKGIPANKLLLGIGFYGRGWNGVTQAAPGGTATGPAPGT
                     YEQGIEDYKVLKNSCPATGTVGGTAYAKCGSQWWSYDTPATINGKMTYAKNQGLGGAFF
                     WELSGDTSNGELIGAIKGGLG"
     gene            3166..3681
                     /locus_tag="Jiend_RS21915"
                     /old_locus_tag="Jiend_45460"
     CDS             3166..3681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735124.1"
                     /locus_tag="Jiend_RS21915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45460"
                     /product="hypothetical protein"
                     /protein_id="WP_111246390.1"
                     /transl_table=11
                     /translation="MRVSFGRSAATAALVTAVSLGLAGCGLGGADEAEAQRVAQAAAEE
                     ALTKSRERVQAYLDAIEAKDVEAGRSQLCAVLHDAFDGAATGPNGDFADHFKVPQTEII
                     DVRPGPAGHEVSASVTVTVGKRKATRPLLFTVTRDGLDWCISDERPGGNSPDPGSGSAT
                     GTAPAPAP"
     gene            3808..5214
                     /locus_tag="Jiend_RS21920"
                     /old_locus_tag="Jiend_45470"
     CDS             3808..5214
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475760.1"
                     /locus_tag="Jiend_RS21920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45470"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_111246391.1"
                     /transl_table=11
                     /translation="MRHEWHQLSHPAVGSQVLQTSRPTVDSAEDAALGLDRWRDLPRAQ
                     TPPWADQAQVAEVCKVLDTVPSVVAPYEVDQLRQRLALVCEGKAFLLQGGDCAETFADN
                     TESHLLANARTLLQMAIVLTYGASLPVVKVARVAGQYTKPRSLPTDARGLPAYRGDMIN
                     SLEATPEARVADPQRMIRAYANSAAAMNMLRAYLAGGLADLHAVHDWNKGFVRNSPAGE
                     RYEAIAREIDRALAFIRACGMTDDDALRTVTLYCSHEALALEYDRALTRVSGNRAYGLS
                     GHFLWIGERTRQIDGAHIDFISRIANPIGVKLGPTTTPDEAIELCEKLNPENIPGRLTL
                     ISRMGNHKVRDALPPIVAKVTAAGAKVVWQCDPMHGNTHESSNGYKTRHFDRIVDEVLG
                     YFEVHRGLETHPGGLHVELTGEDVTECLGGAQGIADLDLPDRYETACDPRLNTQQSLEL
                     AFLVAEMLRG"
     gene            5366..6403
                     /locus_tag="Jiend_RS21925"
                     /old_locus_tag="Jiend_45480"
     CDS             5366..6403
                     /NRPS_PKS="Domain: Beta_elim_lyase (8-283). E-value:
                     1.1e-82. Score: 269.5. Matches aSDomain:
                     nrpspksdomains_Jiend_RS21925_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018800348.1"
                     /locus_tag="Jiend_RS21925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45480"
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="WP_111246392.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 0.00013, bitscore:
                     19.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVAEVIADLRSDTVTRPTAGMREAMATAEVGDDVYGEDPAVNAL
                     EAEVAALFGHEAALFCPTGSMANQIALQLLVPPGAELLCDADAHVVTYEMGAAAAYGGI
                     TSRTWPAVGAEIDPDVVAGMIRPDGYWAVPTRVIAVEQTHNRGGGGVISLDTLRELRRI
                     ADAAQLALHCDGARIWHAHVADGVPLVEYGALFDTLSVCLSKGLGAPVGSLVVGSGERI
                     ARARVIRKRMGGGMRQAGILAAAGRYALAHHVDRLAEDHAKAARLAEAIAPFGILAAPV
                     RTNLVPLDLTKASLDAPTLAAAARAEGVLISVLGPRTARLVTHLDVSDAAITHATTTLT
                     TLLRT"
     aSDomain        5390..6214
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Jiend_RS21925_Beta_elim_lyase.1"
                     /evalue="1.10E-82"
                     /label="Jiend_RS21925_Beta_elim_lyase.1"
                     /locus_tag="Jiend_RS21925"
                     /protein_end="283"
                     /protein_start="8"
                     /score="269.5"
                     /tool="antismash"
                     /translation="DLRSDTVTRPTAGMREAMATAEVGDDVYGEDPAVNALEAEVAALF
                     GHEAALFCPTGSMANQIALQLLVPPGAELLCDADAHVVTYEMGAAAAYGGITSRTWPAV
                     GAEIDPDVVAGMIRPDGYWAVPTRVIAVEQTHNRGGGGVISLDTLRELRRIADAAQLAL
                     HCDGARIWHAHVADGVPLVEYGALFDTLSVCLSKGLGAPVGSLVVGSGERIARARVIRK
                     RMGGGMRQAGILAAAGRYALAHHVDRLAEDHAKAARLAEAIAPFGILAAPVRT"
     gene            complement(6567..7442)
                     /locus_tag="Jiend_RS21930"
                     /old_locus_tag="Jiend_45490"
     CDS             complement(6567..7442)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735121.1"
                     /locus_tag="Jiend_RS21930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45490"
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_111244922.1"
                     /transl_table=11
                     /translation="MPDATPGHRPVGSHTPTSGGLAKAALPYLDATGSQVAQVYVGNSR
                     GWATPAGNPAQDALFRDGCAERDVAVYIHASLLVNLGSPTAATVENSVRTLDHALRRGA
                     EIGARAVVFHAGSAVDAGHAETAMRQVRESLLPLLDSAAATGGPMLLVEPSAGGGRSLA
                     CRVEQLGPYLDAVDRHPWLGVCFDTCHAWAAGHDLAAEGGMTETLDTLVATVGADRLRL
                     VHANDSKDLCGSTRDRHENIGKGMIGEPAFAELMRHPATAGVPVLVETPTERHEGHATD
                     ITTLRRLTTP"
     gene            complement(7442..9439)
                     /gene="pknB"
                     /locus_tag="Jiend_RS21935"
                     /old_locus_tag="Jiend_45500"
     CDS             complement(7442..9439)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735120.1"
                     /locus_tag="Jiend_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45500"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_111244921.1"
                     /sec_met_domain="Pkinase (E-value: 3.6e-47, bitscore:
                     159.4, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 8.1e-06, bitscore: 24.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTQVADTLPGSLIDGRYRIRGRVARGGMATVYTATDERLERTVA
                     IKMIHSTQGTPGRAGAAGFVDRFTDEAKTIARLTHPNVVAVYDQGTHAGSPYLVMEYVH
                     GRTLREVLTERRRLNPDEALAIAEQMLAAIAAAHRAGLVHRDVKPENVLVAEAPSGGPA
                     NLVDGVVKVTDFGLARAVEASTDHDSGNQLMATVAYVAPELVTAGRADARTDVYASGIV
                     LFEMLTGRVPYDGDRPIDIAWQHVDRDVPAPSMLVPGLPRVLDDLVARATRRDPVGRPA
                     DAGALLTEVQAARESLAGTHSHTAMLPSLAAGPVVSEPTMVVAAVRPPERPAWARLPED
                     GAPTRGRRRAAPGRGEGGQDLASRLAGLRTRLLGESQNRLGVAAVVVVLGVVAALGGWW
                     YGVGRYTDAPQLVSMSKAQAEQAASQGGFTLRYADPRYDEQVPRDGVLSQDPASSARIV
                     RGGTITLTLSLGPEKFPLPDVVGKEFELAEADLVSAELKVVKGTARFDDGLPEGVVVAT
                     KPEAGKEVKPGQEITVILSKGRAPITVPNLVGKNLNEARAQISQLGLVLVEPNYKESDK
                     PRDEVLGQSPADGSGVERGAQIRLEVSEGPPLVTVPRVIDLPCQQAKQTLESQGFQVTV
                     QFNPNAVARFQNPPENAQLAPGSQITIGCF"
     gene            9606..9980
                     /locus_tag="Jiend_RS21940"
                     /old_locus_tag="Jiend_45510"
     CDS             9606..9980
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016816979.1"
                     /locus_tag="Jiend_RS21940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45510"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_111244924.1"
                     /transl_table=11
                     /translation="MTDSAPAGNAAPEAGPADWLTLPDVAERLELPISKVHQMIRDREL
                     IAVRRDGVRRIPADLVANHTVLKHLPGVLTLLADAGYDDEAALRWLYEPDDSLPGRTPA
                     TALAGDQAREIKRRAQALGF"
     gene            complement(10001..11083)
                     /locus_tag="Jiend_RS21945"
                     /old_locus_tag="Jiend_45520"
     CDS             complement(10001..11083)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072192.1"
                     /locus_tag="Jiend_RS21945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45520"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_119663691.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.9e-47, bitscore:
                     159.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYAAPVSPVDRASLRRRVDQALTDFLAHRRAWMTELDDALVPVA
                     EAIEAFVLGGGKRLRPAFAYWGYRGAGGVDTDAVVSALASLEFVQASALIHDDLMDRSD
                     TRRGEPAVHRRFAARHRTAAWGGDPDDFGDAAAILLGDLCLVWSDELLHSAGLDPRAVA
                     RARPDFDEMRTEVTVGQYLDVLAQATGDTSVERAGKVARYKSAKYTVERPLLIGAALAD
                     ASAEVRLAYSAYGLPLGEAFQLRDDVLGVFGDPAQTGKPAGDDLREGKRTYLVAAAMEA
                     TDEAGRALLRAGLGDADLDPAGVDRLRELISTTGALARTEQRIVTLTDAALAALVTVDL
                     ETEARQALFDLAIAATRRAD"
     gene            complement(11080..11850)
                     /locus_tag="Jiend_RS32510"
     CDS             complement(11080..11850)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="Jiend_RS32510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_338103577.1"
                     /transl_table=11
                     /translation="MNSKEKVCGEVRTSSPMAGCWFGRIEGRPSATPRLYRVTPLVSPA
                     SHGGDVGKCRTPGLAFGAARGVAEATPGARAGVSTSTGGARLRLGSRSPPHRPLGGAMP
                     PSPPGPPLGPSSPEPSSFGEVLTRFRLARGWSQSRLAAELCAVAGVPTLSRHEISRWER
                     QRRLPGRFWRCWLARVLGLPADLPPPAAGRDRRAGRRGTPTRPPAATRRRGPCAAAPRP
                     AGTRASRPAGTPPAAHPATQASRRAGTGTTSVET"
     misc_feature    complement(11305..11307)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11674..11676)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11756..12673
                     /gene="metF"
                     /locus_tag="Jiend_RS21955"
                     /old_locus_tag="Jiend_45530"
     CDS             11756..12673
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735117.1"
                     /locus_tag="Jiend_RS21955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45530"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_111244919.1"
                     /transl_table=11
                     /translation="MALGLPSILPNQHPAIGELVRTSPQTFSFEFMPPKTEQGERQLWQ
                     AIRELEPLRPSFVSITYGAGGSTRDTTVAVTERVATETTLVPMAHLTAVNHSVAELRHV
                     IGRLAGAGVRNVLAVRGDPPGDPTGEWVPHPEGVHYAEDLVRLVRQSGDFSVGVAAFPY
                     RHPRSPDVATDTEYFVRKCRAGAEFAITQMFFDADEYLRLRDRVAATGCDTPILAGVMP
                     VTRIGTIERAVQLSGAPFPPALAARFERVADDPEAIRQLGIEQTSEMCQRLLDEGVPGI
                     HFITFNRSTATRQIWQNLRVSAAT"
     gene            12747..13436
                     /locus_tag="Jiend_RS21960"
                     /old_locus_tag="Jiend_45540"
     CDS             12747..13436
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014460.1"
                     /locus_tag="Jiend_RS21960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45540"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_111244918.1"
                     /transl_table=11
                     /translation="MVGRQLNWNEYATAWARLHGGFDPRAATPVVRGWLRFSYHLGFLL
                     GRLRVGPTAVTVVGVLLCLCVPLLAGRPGDGPFLAAAFVLLASVADSVDGAVAVVTGRT
                     TRLGYVYDSLADRLGEAAWLVAFWLVGAPGALVAAAGALSWLHEYVRARAVAAGMREIG
                     AVTVGERPTRVCVAVAGLLLAGLTGLVQLDLAAGTITMATAVWVLLAAFGLGQLLSAVR
                     RALIDAA"
     gene            complement(13502..14986)
                     /gene="crtI"
                     /locus_tag="Jiend_RS21965"
                     /old_locus_tag="Jiend_45550"
     CDS             complement(13502..14986)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688697.1"
                     /locus_tag="Jiend_RS21965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45550"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_111244917.1"
                     /sec_met_domain="DAO (E-value: 7.4e-11, bitscore: 40.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARIVVIGAGVGGLAAAARLAVTGHQVTVLERAETVGGKLGRHTR
                     DTAEGSFHFDTGPSLLTLPQVFHDLFEATGAKLDEYLDLVPLDPIVRHVFPGGGPVLDS
                     CADPEEFAARIGTAFGDRAAADWQRLWRRAARVWRASEHDILRRRVDSPRDLARLAWRL
                     GDLAAIRPGQSLRGLGRAQLADPRLRMLLDRYATYTGADPRRAPAALVAVPYAELAFGG
                     WYLRGGLGTLADALLSRCLDLGVVVRTGATVTRIDAVGGRVHGVRVADQHAPIPADVVV
                     ANVDALTLYRDLLPDPRRLAGLADRSLAGFVLLLGVRGESGLAHHNVFFPRDYDAEFDA
                     VFGDPGRGVRARPATDPTVFVTVADDPTARPNGHEAWFVLVNAARQGTAAGAVDWRRPG
                     LAQAYADRILDVLAERGVDVRDRLLFRDIRTPADLATATGAPGGTIYGTAGGLLRPANR
                     GPAHGLWLVGGSSHPGGGLPMVTLSAHLVADAIGWV"
     gene            complement(14998..16128)
                     /locus_tag="Jiend_RS21970"
                     /old_locus_tag="Jiend_45560"
     CDS             complement(14998..16128)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441608.1"
                     /locus_tag="Jiend_RS21970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45560"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_111244916.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5e-13, bitscore:
                     47.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGFSLTALGLLVVLTGHTVVNAGRWLRRPTDQPVTRTEPVTVLL
                     PLRDEAARVTPCLRALLAQRGVPGLRIVVLDDGSTDGTADVVRAVAAGDPRVTLLTGVA
                     PPPGWLGKPHACWQLATRVGASADALVFVDADVVLAPYAVAAAVTELRAAGATLLSPYP
                     RIVVRTAADRLVQPLLQWLWLTFLPLRAMERSSRPSLAAAGGQFLVVDRAGYLRAGGHA
                     AVADRVLEDIELARAVKRAGGRIALADGSRLATCRMYENWPQLRDGYTKSLWASFGHPG
                     NAALVVALLLVLYTAPPLVAVAALLAGAPALAGIAGLAYLTGVAGRVISARATGGRAWP
                     DALGHPVSVAVLGWLTLRSYHLRKRRRLSWRGRPVD"
     gene            complement(16125..16970)
                     /locus_tag="Jiend_RS21975"
                     /old_locus_tag="Jiend_45570"
     CDS             complement(16125..16970)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735113.1"
                     /locus_tag="Jiend_RS21975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45570"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_111244915.1"
                     /transl_table=11
                     /translation="MTRLARGYAWTLLALLVLAQIGYPLTAGTTRARLTVATVVLGYLL
                     SVGHALLSRGTRTALALVALATGGGLAIEALGVATGFPFGSYDYSGQLGPKLAGVPLII
                     PLAWTWMAWPAWLVATRLVKRWPGRIALATLGLATWDLFLDPQMVAEGHWVWRDAEPAL
                     PGLPGIPVSNYLGWLLFAVLVMTALRPLAGPAVADTDARDHPLYALYLWTYGGSVLAHA
                     VFLDLPASAVWGAAGMALVAVPLAVTLLRERRHRDRDTGPARPPERSTEADRPPADAAT
                     "
     misc_feature    complement(16758..16760)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16967..17530)
                     /locus_tag="Jiend_RS21980"
                     /old_locus_tag="Jiend_45580"
     CDS             complement(16967..17530)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785285.1"
                     /locus_tag="Jiend_RS21980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45580"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_111244914.1"
                     /transl_table=11
                     /translation="MRLVRWTPDDLLRRLNDVVAVYGEAMGYRLDLLEARRGYIATHVR
                     RPGFRAVASLTSEGHLAGFGYGYLGGPGQWWHDQVARALDPAARQRWLTDCFEVVELHV
                     RPPAQGHGLGAGQLRALLTMAEGRTVLLSTPEADEATSRAWRLYRRFGFVDVLRDFRFP
                     GDERPFGVLGRDLPLPAPEHVDRS"
     gene            complement(17527..18267)
                     /locus_tag="Jiend_RS21985"
                     /old_locus_tag="Jiend_45590"
     CDS             complement(17527..18267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735111.1"
                     /locus_tag="Jiend_RS21985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45590"
                     /product="monooxygenase"
                     /protein_id="WP_111244913.1"
                     /transl_table=11
                     /translation="MNELENVPELVTLHVWRVPRSALPRVLLRMARDPRRLRALPGVRF
                     GKLLGTGTGTGFGPNDADPTRWAALTVWESPAAATRFAGSPVDRAWSGIATAGVRLDLR
                     PLTSRGEWSGRRPFGEPTGGRVTGPVLALTRARLRPTRALTFWRAVPPVAAALRTAPGL
                     LARFGVGEAPLGWQGTVSVWRDPADLVAFAYRHPEHRAAITRTDTERWYAEELFARFEV
                     RDVIGDRSVLGWAADGDPAKGERA"
     gene            complement(18264..18752)
                     /locus_tag="Jiend_RS21990"
                     /old_locus_tag="Jiend_45600"
     CDS             complement(18264..18752)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018742850.1"
                     /locus_tag="Jiend_RS21990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45600"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_111244923.1"
                     /transl_table=11
                     /translation="MQSHPNVRAVQDALADVDARDGAGGPATVRLLPDAVHTAAAAAEA
                     LGVDVGAIANSLIFDADGTPLLVLTSGAHRVDTAGLAARIGVTRLRRATPQFVKEHTGQ
                     VIGGVAPVGHPHPLRTLVDTALDKYDEIWAAGGVPQAVFPSTYAELLRVTGGTPTDVA"
     misc_feature    18888..18903
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.7"
                     /tool="antismash"
     misc_feature    complement(18889..18902)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.82"
                     /tool="antismash"
     misc_feature    18909..18924
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    complement(18910..18923)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.91"
                     /tool="antismash"
     gene            19232..19681
                     /locus_tag="Jiend_RS21995"
                     /old_locus_tag="Jiend_45610"
     CDS             19232..19681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018730710.1"
                     /locus_tag="Jiend_RS21995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45610"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_111244912.1"
                     /transl_table=11
                     /translation="MPTSPAPAPTVPAHVLPHRTPAQLLTVARHGLAEAARTGPDGLRY
                     AAAHLAALRAAAAVLAARARPAPTRRNRVTSVWVLLATVAPELDEWATYFALGAGKRAA
                     AEAGIPRVVTAREADDLLRAAEEFVAVVETALGLTHQPAIDGLVA"
     gene            19827..20549
                     /locus_tag="Jiend_RS22000"
                     /old_locus_tag="Jiend_45620"
     CDS             19827..20549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463068.1"
                     /locus_tag="Jiend_RS22000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_45620"
                     /product="hypothetical protein"
                     /protein_id="WP_111244911.1"
                     /transl_table=11
                     /translation="MAGRMVVGSAALAGLVRPASAPDPAGGHRVLPVRSELTGLLPGRG
                     LRRGSTIAVGAGQLRSSGTTSLLFALLAEASQAGSWCAVVGLPTFGAGAAAEAGIALDR
                     LALVPQPGPDWPTVVAALIDGVDVVVAAVPATVSASVASRLAARARQRGCVLVPYGRWD
                     GADVMLQVVRGVWDGLGPGRGRLRRREVTISARGRGAAARPKEVKVWLPDAELTRIIPR
                     STGAGRPGAAGLRVVVSA"
ORIGIN
        1 cgacgacgcg cacctgcgtc cgctgaaccc ctggcacgcc gaggagttcc tggccaatct
       61 ggaccggggc cgggagagca tgctgccgtg ggtgtcgcca tccttcgtgg ccgctgatct
      121 cgacggcgcg cggcacgtgc tccagcgcta cgccgacagg tgggcccgtg acgacggcgg
      181 gatctggggc atctggtccg gtgacaccct ggtcggcggg gtgctgctgg tgtcgttgag
      241 caccgcgacc ggagtctgcg aggcgggttg ctggctggaa ccggccgccg aggggcgggg
      301 cctggtgacc cgcgcggtca gccggctcat cgactgggtg gtcgacgagc gcggcctgca
      361 ccgggtcgag tggcgggtga ccgccggcaa cgtacgcagc atcgcggtgg cccgccggct
      421 aggcatgcgc cgggacggcg tactgcgtca ggtggcgccc ggcccggacg gccggatcga
      481 cctggagatc tggtcggtgc tggcgcccga gtggcgggcc cggcgcgacg gcggcgtcgc
      541 ggactgaacg gccgggctca gccggccttg gcgagcgccg cccgcagctt gccgatgtca
      601 cccggggcgg cctgctccca gttggtcggg tcggcagagt agatgacgcc gtaggccggg
      661 gtgtccggct ggaaacgcca actgtcggcg agggcgccgg cgtcgaacgc gtcgtagccg
      721 atccggtcga ggaaagcggt ggcggcgctc ttggcctgtg ggtcgtcgcc ggcgatcggc
      781 aacgcgctgc gatcggccgc gccggtgggg cgggccagcg cgagcaggtg cttgaagaag
      841 atgttgttga acgccttcac cacccgcgcc tcgggtagct ggcgttgcag cagctcgctg
      901 ctggtggtgg cgccatcgtc caactccggg aactgaccgt cccgttccgg gtagtagttg
      961 ttggtgtcga tgacgagctt gccggccagc ggtgcggccg gcaccgaccg gtacgccttg
     1021 agcgggatgg tgaccacgac caggtcaccg gcgcgggctg ccgcctcgac ggtgcccgcg
     1081 ctggcctgtg gacccagttc gtccaccagg tcggcaaggg tttccggccc ccgtgagttg
     1141 ctcaacacca cgtcgtaacc ggcgttgacc gccaaccgcg cgaccgtccc cccgatgtgc
     1201 ccactcccga taaaccccac ggtggtcaca gacccactcc cttcgtccct tgcgaacgta
     1261 ccccgcaccc gcgcttccca cccgtcgctc gccgggacag ggcgttgacc ggggtcaccc
     1321 ggacgattga tcgatacatg gacatcttga cgaagtggtg tcgtgtgagt agcgtctcct
     1381 catccttttg gaaagtttcc taactgtttg gaggcgccac atgaagagat cgctccggcg
     1441 ggccctctgg ctcggtgccg tggtcgcggt gaccgtcgcc accgtcccga tggcctccgc
     1501 gttcggcgcc ggaaacgtga ccgcctcgtt cacccgggcg tcggactggg ggaccggtca
     1561 cgaaacgaag gtcaccatca ccaacggttc gagcgccagc gtcagcacct ggcggatcga
     1621 gttcgagctg cccgcgggca ccaccatcag cagctcctgg gacgccgacg tcacccgcga
     1681 cggcaaccgg tacgtggcgg tcaagaagag ctgggccggt gccctggccc ccggcgactc
     1741 cttcagctgg ggttacaacg gcaccggcgg gtatcgggcg ccgctgaact gcaccgtcaa
     1801 cggcgcggcc tgcggcggtg gcacgacccc accgaccacc acgcccacca ccaccccgcc
     1861 cacgaccacg ccgccgacca ccaccccgcc gaccacgacg ccacccacca ccccgcccag
     1921 cggggaccgc aaggtcgtcg gctacttcgc ccagtggggc gtctacgccc gcaactacca
     1981 cgtcaagaac atccacacca gcggctcggc ggccaagctg acccacatcc tgtacgcctt
     2041 cggcaacacc accggcggcc ggtgcaccat cggtgacagc tacgccgact acgagaaggc
     2101 gtacaccgcg gcggagagcg tcgacggcgt cgccgacacc tgggaccagc cgctgcgggg
     2161 cagcttcaac cagctgcgca agctcaagaa gatgtacccg cacctcaagg tgatctggtc
     2221 cttcggcggc tggacctggt ccggtggctt cacgcaggcc gcgcagaacc cggccgcctt
     2281 cgccgagagc tgctacaacc tggtggagga cccgcgctgg gcggacgtct tcgacggcat
     2341 cgacatcgac tgggagtacc ccaacgcctg cggcctgacc tgtgacgcca gcggcccgaa
     2401 cgcgttcaag aacgtggcca gcgcactgcg tagccggttc ggctcgggca acctggtcac
     2461 cgccgcgatc accgcggacg gcagcaacgg cggcaagatc gacgccaccg actacgccgg
     2521 tgccgccacc cacctcaact ggatcatgcc gatgacgtac gactacttcg gcgccttcgc
     2581 cccgcagggc cccaccgccc cgcactcgtc gctctactcg tacaccggca tcccgcagca
     2641 gggcttctgg tcggacgcgg ccatccagaa gctcaagagc aagggcatcc ccgccaacaa
     2701 gctgctgctc ggcatcggct tctacggccg gggctggaac ggggtgaccc aggccgcgcc
     2761 gggcggcacc gccaccggtc ccgcgccggg cacgtacgag cagggcatcg aggactacaa
     2821 ggtgctcaag aacagctgcc cggccaccgg caccgtcggc ggtacggcat acgccaagtg
     2881 cggcagccag tggtggagct acgacacccc ggccaccatc aacggcaaga tgacgtacgc
     2941 gaagaaccag ggcctcggtg gcgccttctt ctgggagctc tccggtgaca ccagcaacgg
     3001 cgagttgatc ggcgccatca agggcggcct cggctgagcc gacggccgac gcaccaccca
     3061 cgacggggag gggcccgcgc cggcccctcc ccgtttcccg tgcaccgtga tgtggcagac
     3121 tcgttcgctc gggtgactct cggtgtccgt ttgtcggagg tagcgatgcg ggtcagtttc
     3181 ggtcgctcgg cggcgactgc cgccctggtc accgcggtgt cgctcgggct tgccggctgt
     3241 gggctcggcg gtgccgacga ggccgaggcg cagcgggtcg cgcaggcggc ggccgaggag
     3301 gccctgacga agtcccggga gcgggtccag gcctacctgg acgcgatcga ggcgaaggac
     3361 gtcgaggcgg ggcgcagcca gctctgcgcg gtgctgcacg acgcgttcga cggggcggcc
     3421 accgggccga acggtgactt cgccgaccac ttcaaggtgc cgcagaccga gatcatcgac
     3481 gtccgccccg gcccggccgg gcacgaggtg agcgcctcgg tcacggtgac ggtgggcaag
     3541 cgcaaggcca cccgtccgtt gttgttcacc gtcacccggg acgggctcga ctggtgcatc
     3601 tccgacgaac ggcccggcgg gaacagcccc gacccgggat cggggtcggc caccgggacc
     3661 gcgcccgccc cggcaccctg accgtccggc gcgaggaacc gggaccggtg cggctggtca
     3721 ccgggatccg gacgaaccgc cgtccatcta ccggaaccgg ggccctcgcc ggtcggccac
     3781 cgcgccggtc gccgtacgct ttctgtcatg cgccatgagt ggcaccagtt gagtcatccg
     3841 gcggtcggca gccaggtgtt gcagaccagc cgcccgaccg tcgactccgc cgaggacgcg
     3901 gccctcggcc tggaccggtg gcgggacctg ccgcgcgccc agaccccgcc ctgggcggat
     3961 caggcccagg tcgccgaggt ctgcaaggtg ctcgacacgg tcccgtcggt cgtcgcgccg
     4021 tacgaggtcg accagttgcg gcagcgcctt gcgctggtct gcgagggcaa ggcgttcctg
     4081 ctccagggtg gcgactgcgc ggagaccttc gccgacaaca ccgagagcca cctgctggcc
     4141 aacgcccgca ccctgctcca gatggcgatc gtgctcacct acggcgcgtc gctaccggtg
     4201 gtcaaggtgg cccgggtcgc cgggcagtac accaagcccc ggtcgctgcc gaccgacgcc
     4261 cggggcctgc cggcctaccg cggcgacatg atcaactcgc tggaggccac gccggaggcg
     4321 cgggtcgccg acccgcagcg catgatccgg gcgtacgcga actccgccgc cgccatgaac
     4381 atgctccgcg cctacctcgc cggtggcctg gccgacctgc acgccgtgca cgactggaac
     4441 aagggcttcg tgcgcaactc cccggccggc gagcggtacg aggccatcgc ccgcgagatc
     4501 gaccgggcgc tggccttcat ccgggcctgc gggatgaccg acgacgacgc cctgcgtacg
     4561 gtcaccctct actgctcgca cgaggcgctg gcgttggagt acgaccgggc gctgacccgg
     4621 gtctccggca accgggcgta cgggctgtcc gggcacttcc tctggatcgg cgagcgcacc
     4681 cggcagatcg acggcgcgca catcgacttc atctcccgca tcgccaaccc gatcggggtc
     4741 aagctcggcc cgaccaccac cccggacgag gcgatcgagc tgtgcgagaa gctgaacccg
     4801 gagaacatcc ccggccggct cacgctgatc agccggatgg gcaaccacaa ggtacgcgac
     4861 gcgctgccgc cgatcgtggc gaaggtgacc gccgccgggg cgaaggtggt gtggcagtgc
     4921 gacccgatgc acggcaacac ccacgagtcg tcgaacggtt acaagacccg ccacttcgac
     4981 cggatcgtcg acgaggtgct tggctacttc gaggtgcacc gtggcctgga gacccacccg
     5041 ggcggtctgc acgtcgagct gaccggcgag gatgtcaccg agtgcctggg tggcgcacag
     5101 ggcatcgccg atctcgacct gccggaccgg tacgagaccg cctgtgaccc gcgactgaac
     5161 acccagcagt cgctggaact ggccttcctc gtagcggaga tgctccgtgg ctgagcttgc
     5221 gagccccgca gtcggcagcc gggagggatg atcgtggctg acgcgaggag tgagcttgcg
     5281 agccccgcag tcggcggccg ggagggatga tcgtggctga cgcgaggagt gagcttgcga
     5341 gccccgcagt cggcggccgg aagggatgat cgtggctgag gtgatcgcgg atctgcgttc
     5401 ggacacggtg acccggccca cggccgggat gcgcgaggcg atggccactg ccgaggtcgg
     5461 cgacgacgtc tacggcgagg atccggcggt caacgcgctg gaagccgagg tcgccgcgct
     5521 gttcgggcac gaggcggcgc tgttctgccc gaccgggtcg atggccaacc agatcgccct
     5581 gcaactgctg gtgccgccgg gcgcggaact gctctgcgac gccgacgcgc acgtggtcac
     5641 gtacgagatg ggggccgctg ccgcgtacgg cggcatcacc tcgcggacct ggcctgccgt
     5701 cggtgcggag atcgaccccg acgtggtcgc cggcatgatc cggcccgacg gctactgggc
     5761 ggtgcccacc cgggtcatcg ccgtggagca gacccacaac cgtggcggcg gtggggtgat
     5821 ctccctcgac accctgcgtg agctgcgccg gatcgcggac gcggcacagc tggcgctgca
     5881 ctgcgacggt gcccggatct ggcacgcgca cgtcgccgac ggggtgccgc tggtcgaata
     5941 cggcgcgctc ttcgacaccc tctcggtctg cctgtccaag ggactcggcg cgccggtcgg
     6001 ctccctggtg gtgggctccg gcgagcggat cgcgcgggcc cgggtgatcc gcaagcggat
     6061 gggcggcggc atgcgtcagg ccggcatcct ggccgcggcc ggacggtacg ctctcgccca
     6121 ccacgtcgac cggctcgccg aggaccacgc gaaggcggcc cggctggccg aggcgatcgc
     6181 accgttcggg atcctggccg ccccggtacg caccaacctg gtcccgctgg atttgaccaa
     6241 ggcgtcgctg gacgcgccca ctctggccgc cgccgcccgc gccgagggag tgctcatctc
     6301 ggtgctcggt ccccgtaccg cccgcctggt cacccacctc gacgtgtcgg acgccgccat
     6361 cacccacgcc accaccaccc tcaccaccct cctccgcacc taaccccacc ccaccccacc
     6421 ccacccgccc ctcgctcccc gcccccttct ccccgcgatc ttgcactttt ggtcgccgga
     6481 atgcccggta tgcggttaat gcggcgacaa aaagtgcaag atcgcgacgg ctggggaggc
     6541 gcgggggcgt ggggggcggg ggcgtgttag ggggtggtta ggcggcggag ggtggtgatg
     6601 tcggtggcgt ggccctcgtg acgctcggtg ggggtctcca ccaggacggg tacgccggcg
     6661 gtggcgggat ggcgcatcag ctcggcgaag gccggctcac cgatcatgcc cttgccgatg
     6721 ttctcgtgcc ggtcgcgggt ggagccgcac aggtccttcg agtcgttggc gtgcaccagc
     6781 cgcagccgat ccgcgccgac ggtggccacc agggtgtcca gcgtctcggt catgccgccc
     6841 tcggcagcca ggtcgtgccc ggccgcccag gcatggcagg tgtcgaagca gacaccgagc
     6901 caggggtggc gatccaccgc gtcgaggtac ggccccagct gctccacccg gcaggccagt
     6961 gaccggccgc cgcccgcgct cggttcgacg agcagcatcg gtccgccggt ggcggcggcc
     7021 gagtccagca gcggcaacag cgactcgcgt acctgccgca tggccgtttc ggcgtgcccg
     7081 gcgtccaccg cgctgccggc gtggaagacc accgcgcggg caccgatctc ggccccacgg
     7141 cgcagcgcgt ggtcgagcgt ccgcaccgaa ttctcgaccg tggcggcggt cggcgaaccc
     7201 aggttgacca gcagcgacgc gtggatgtag acagctacgt cccgctcggc gcagccgtcg
     7261 cggaacagcg cgtcctgagc cgggttgccc gccggtgtgg cccagccgcg ggagttgccg
     7321 acgtagacct gggccacctg ggagccggtg gcgtcgaggt acggcagtgc cgccttggcc
     7381 aacccgccgg aggtgggcgt gtgcgaaccg accggccggt ggccgggagt tgcgtcgggc
     7441 atcagaagca tccgatggtg atctggctgc ccggtgccaa ctgggcgttc tccggcgggt
     7501 tctggaaccg ggcgaccgcg ttcgggttga actgcacggt cacctggaag ccctggctct
     7561 ccaacgtctg cttggcctgc tgacatggca ggtcgatgac ccggggcacg gtcaccagag
     7621 gcggaccctc gctgacctcc agccggatct gggcaccccg ctccactccg ctgccatcgg
     7681 ccgggctttg cccgagcacc tcgtcgcggg gcttgtcgga ctccttgtag ttcggttcca
     7741 cgagcaccag accgagttgc gagatctggg cgcgggcctc gttgaggttc ttgccgacca
     7801 ggttcggcac ggtgatcggt gcccgaccct tgctgaggat gacggtgatc tcctgacccg
     7861 gcttgacctc cttgcccgcc tcgggtttgg tggccaccac cacaccctcg ggcaggccgt
     7921 cgtcgaagcg ggcggtgccc ttgacgacct tgagctcggc gctgaccaga tccgcctcgg
     7981 ccagctcgaa ctccttgccc accacgtccg gcagggggaa cttctccgga ccgagggaga
     8041 gggtcagggt gatggtgccg ccccgcacga tccgggcgga cgacgccggg tcctgggaga
     8101 gcacaccgtc gcgcggcacc tgctcgtcgt agcgcgggtc ggcgtagcgc agggtgaagc
     8161 cgccctggga ggccgcctgc tccgcctgcg ccttgctcat gctcaccagc tgtggcgcgt
     8221 cggtgtaccg gcccacgccg taccaccagc cgccaagggc ggccaccaca ccgagcacca
     8281 ccaccacggc ggcgacaccg aggcggttct gcgactcgcc cagcagccgg gtccgcagcc
     8341 ccgccagccg ggaagccagg tcctgaccac cctcgccccg acccggcgcg gcgcgacgtc
     8401 ggccccgggt gggtgctcca tcctccggca gtcgcgccca ggccggccgc tccggcgggc
     8461 ggaccgcggc caccaccatc gtcggctcgg acaccaccgg cccggcagcc agggacggca
     8521 gcatggcggt gtggctgtgc gtaccggcga gactctcccg ggcggcctgc acctcggtca
     8581 gcagcgcccc ggcgtccgcg ggtcggccca ccggatcccg cctggtggcg cgggccacca
     8641 ggtcgtcgag cacccgaggc aggccgggca ccagcatcga cggggcgggc acatcccggt
     8701 cgacgtgctg ccaggcgatg tcgatcggcc ggtcaccgtc gtacggcacc cggccggtga
     8761 gcatctcgaa caggacgatg cctgacgcgt agacgtcggt acgggcgtcg gcgcggcccg
     8821 cggtgaccag ttcgggggcg acgtacgcca ccgtggccat cagctggtta ccgctgtcgt
     8881 ggtcggtgct ggcctcgacg gcccgggcca gtccgaagtc ggtgaccttg accacgccgt
     8941 cgacgaggtt ggccgggccg ccgctgggcg cctcggcgac gagcacgttc tccggcttga
     9001 cgtcgcggtg caccagtccg gcccggtggg cggcggcgat cgcggcgagc atctgctcgg
     9061 cgatggccag tgcctcgtcc gggttgagtc gacgtcgctc ggtcaacacc tcgcgcaggg
     9121 tgcgcccgtg cacgtactcc atgaccaggt acggcgatcc ggcgtgggtg ccctggtcgt
     9181 agaccgccac cacgttgggg tgggtgagcc gggcgatcgt cttggcctcg tcggtgaacc
     9241 ggtcgacgaa acccgctgcc ccggcgcggc ccggcgtgcc ctgcgtcgag tgaatcatct
     9301 tgatcgccac ggtgcgttcg agccgctcgt cggtggcggt gtacaccgtg gccatgccgc
     9361 cacgagccac gcgaccgcgg atgcggtagc gcccgtcgat cagcgagccc ggcaacgtgt
     9421 cggcgacctg tgtgtccatc ggcagggagt ctatgtgtca ggggtacgaa ggttgaacac
     9481 cgatgctacc gccgcatcgc cgccagcggg ttcaccctgc ccgtgacgcg cccggtgtgc
     9541 cctgctcaac gtggtcaccg ggaggctgtt ggccccgggc aggggtggcg tggcagggtg
     9601 gtgtggtgac cgactccgca cctgccggga acgccgcgcc cgaggccggc cccgccgact
     9661 ggttgaccct gccggatgtc gctgagcggc tcgagctgcc gatcagcaag gtccaccaga
     9721 tgattcggga ccgggagctg atcgcggtac gccgcgacgg tgtccgccgg atcccggccg
     9781 acctggtggc caaccacacc gtgctcaagc acctgcccgg cgtgttgacc ctgctcgccg
     9841 acgccggcta cgacgacgag gcggcgctgc gctggctcta cgagcccgat gacagcctgc
     9901 ccggtcgtac ccccgccacc gccctcgccg gcgaccaggc ccgcgagatc aagcgccgcg
     9961 cccaggccct cggtttctga ccccccaccg ccccggcggg tcagtcggcg cggcgggtgg
    10021 cggcgatggc caggtcgaac agggcctggc gggcttcggt ctccaggtcg acagtgacca
    10081 gtgcggcgag tgcggcgtcg gtgagcgtga cgatccgctg ctccgtgcgg gccagcgcgc
    10141 cggtggtgga gatcagttcc cggagccgat ccaccccggc cgggtccagg tccgcgtcgc
    10201 ccagaccggc gcgcagcagc gcccggccgg cctcgtcggt cgcctccatc gccgccgcca
    10261 ccaggtaggt ccgcttaccc tcgcgcaggt cgtcgccggc cggcttgccc gtctgcgccg
    10321 ggtcgccgaa cacccccagc acgtcgtcgc gcaactggaa cgcctcaccg agcggcaagc
    10381 cgtacgccga gtaggcgagg cgcacctcgg cggaggcgtc ggccagcgcc gcgccgatca
    10441 gcaacggacg ctccaccgtg tatttcgccg acttgtagcg ggcgaccttc cccgcccgct
    10501 ccaccgaggt gtccccggtc gcctgggcca gcacatcgag gtactgcccg acggtgacct
    10561 cggtgcgcat ctcgtcgaag tcgggccgcg cgcgggccac cgcccggggg tcgagcccgg
    10621 ccgagtgcag caactcgtcg gaccagacca ggcagaggtc gcccagcagg atcgccgcgg
    10681 cgtcaccgaa atcgtccgga tcgccacccc aggcggccgt ccgatgccgg gcggcgaacc
    10741 ggcggtgcac cgccggttcg ccgcggcggg tgtccgaacg gtccatcagg tcgtcgtgga
    10801 tcagcgcgct ggcctggacg aactccagcg aggcgagggc gctcaccacc gcgtcggtgt
    10861 ccactccacc ggcgccccgg taaccccagt aggcgaaggc gggtcgcaac cgttttcctc
    10921 cgcccagcac gaacgcctcg atggcctcgg caaccggcac cagggcatcg tcgagctcgg
    10981 tcatccaggc ccggcggtgg gcgaggaagt cagtcagggc ctggtcgacc cgtcggcgca
    11041 ggctggcgcg gtcgaccggg gataccggag cagcgtaggt cacgtctcga cgctagtggt
    11101 tccggttccg gcgcgtcgag aagcctgcgt tgcggggtgc gcagccggtg gcgttccggc
    11161 gggtcgggac gccctcgttc cggccggtcg tggtgcggct gcgcacggcc cgcggcgtcg
    11221 ggtggcggcc ggcggccggg tcggggtgcc gcggcgcccg gcccggcggt cgcggccggc
    11281 ggcgggaggc ggcaggtcgg ccggtaaccc gaggaccctc gccaaccagc agcgccagaa
    11341 gcggccgggc agccgccgct gccgctccca ccgtgagatc tcgtgccgac tcaaggtggg
    11401 tacgccggcg acggcgcaga gctcggcggc gagccgggac tggctccagc cccgggcgag
    11461 tcggaaccgg gtcagcacct ccccgaacga cgacggctcc ggcgacgacg ggccgagtgg
    11521 tggaccgggc ggggacggcg gcatcgctcc tccaaggggt cggtgtggcg gtgaccggct
    11581 gccgagacgc agccgtgcgc cacctgtcga ggtgctgacc cccgcgcgtg cccccggtgt
    11641 ggcctccgcc accccccgcg ctgcaccgaa ggctaatccc ggcgtacgac acttcccgac
    11701 gtcgccgccg tgggaagctg gtgagacgag tggtgtcacc cgatagagtc gtggcgtggc
    11761 gctcggtctt ccctcgatcc ttccgaacca gcacccggcc atcggggagc tggttcgcac
    11821 ctctccgcag accttctcct tcgagttcat gccgcccaag accgagcagg gggaacggca
    11881 actctggcag gccatccgcg agttggagcc gctgcgcccg tccttcgtct cgatcacgta
    11941 cggggccggc ggatcgaccc gggacaccac cgtggcggtc accgaacggg tcgccaccga
    12001 gaccaccctg gtgccgatgg cgcacctgac cgcggtcaac cactccgtgg ccgagctgcg
    12061 gcacgtgatc gggcggctgg ccggagccgg ggtgcgcaac gtgctcgcgg tccgcggtga
    12121 cccgcccggc gaccccaccg gcgagtgggt gccgcacccc gagggcgtgc actacgcgga
    12181 ggatctcgtc cggctggtcc gccagtccgg cgacttcagt gtcggcgtgg ccgccttccc
    12241 gtaccgccac ccgcgctcgc cggacgtcgc caccgacacc gagtatttcg tccgcaagtg
    12301 ccgggccggt gcggagttcg cgatcacgca gatgttcttc gacgccgacg agtacctccg
    12361 cctgcgggac cgggtcgccg cgaccggttg cgacacgccg atcctggccg gagtgatgcc
    12421 ggtgacccgg atcggcacga tcgaacgcgc ggtgcagctt tccggcgcgc ccttcccccc
    12481 ggcactggcg gcccggttcg agcgggtggc cgacgatccc gaggcaatcc gccaactcgg
    12541 catcgagcag accagcgaga tgtgtcagcg gctgctcgac gagggcgtcc ccgggatcca
    12601 cttcatcacc ttcaaccggt ccacggcgac ccggcagatc tggcagaacc tccgggtgag
    12661 cgccgcgacg tgactccccg ggcgcgacat cgcgacacgg tcgtccccgg atcgcgacac
    12721 ctcggcccca ccgcgccggt tgaactgtgg tgggcagaca gctgaactgg aacgagtacg
    12781 ccacggcgtg ggcgcggctg cacggtgggt tcgatccccg cgccgccact cctgtggtac
    12841 gaggctggct gcgtttctcc taccacctgg gtttcctgtt gggccggctg cgggtcggcc
    12901 ccaccgcggt gacggtggtg ggggtactcc tctgtctctg cgtaccgctg ctcgcgggcc
    12961 ggccgggcga cgggccgttc ctggccgcgg cgttcgtgct gctcgcctcg gtggccgaca
    13021 gtgtcgacgg ggcggtggcg gtggtcaccg gccggacgac ccgcctcggg tacgtctacg
    13081 actcgcttgc cgaccggctc ggtgaggcgg cctggctggt ggcgttctgg ctggtcggcg
    13141 cgcctggcgc actggtcgcc gcggccggcg cgctgtcctg gctgcacgag tacgtccggg
    13201 cccgcgcggt cgccgccggg atgcgggaaa tcggcgcggt caccgtcggg gagcggccca
    13261 cccgggtctg cgtggcggtg gccgggctgc tgctggccgg actgaccggg ctggtccagc
    13321 tggacctggc cgccggcacg atcaccatgg ccaccgcggt ctgggtgttg ctggccgcct
    13381 tcgggctcgg gcaactgctc tccgcggtac gccgggcgct catcgacgcc gcttgagtgc
    13441 cctccgctgg tgttaacagg gggcccctcc tctaccccag gcgttaacag gggccccctg
    13501 cttacaccca gccgatggcg tcggcgacga ggtgggcgga gagggtgacc atcggcaggc
    13561 cgccgcccgg atggctggag ccgccgacca gccagaggcc gtgcgccggg ccccggttgg
    13621 cggggcggag caggccaccg gcggtgccgt agatggtgcc gccgggcgcg ccggtggcgg
    13681 tggccaggtc ggccggggta cggatgtcgc ggaagagcag ccggtcgcgt acgtccacgc
    13741 cgcgttcggc gagcacgtcg aggatccgat cggcgtacgc ctgcgccagc cccggccgcc
    13801 gccagtcgac cgccccggcg gcggtgccct ggcgggccgc gttgaccagc acgaaccacg
    13861 cctcgtggcc gttcgggcgg gcggtcgggt cgtcggcgac ggtgacgaag accgtcgggt
    13921 cggtggccgg ccgggcccgc accccgcgac ccgggtcgcc gaagaccgcg tcgaactcgg
    13981 cgtcgtagtc gcgcgggaag aagacgttgt ggtgggccag cccgctctcc ccgcgtacgc
    14041 cgagcagcag cacgaagccg gccaggctgc ggtcggcgag gccggccagc cggcgtgggt
    14101 cgggcagcag gtcccggtag agggtgagcg cgtccacgtt cgccaccacc acgtcggcgg
    14161 ggatcggggc gtgctggtcg gcgacgcgta cgccgtgcac ccggccgccc accgcgtcga
    14221 tccgggtgac cgtggcgccg gtacgcacca ccacccccag gtccaggcag cgcgacagca
    14281 gcgcgtcggc gagcgtgccc aacccgccgc gcaggtacca gccgccgaag gccagctcgg
    14341 cgtaggggac cgcgaccagc gcggccggcg cccggcgcgg gtcggcgccg gtgtaggtgg
    14401 cgtaccggtc cagcagcatc cgcagccgtg ggtcggcgag ctgggcccgg cccaacccgc
    14461 gcaggctctg cccgggccgg atcgcggcca ggtcaccgag gcgccaggcc agccgggcca
    14521 ggtcgcgggg cgagtcgacc cgacggcgca ggatgtcgtg ttcgctggcc cgccacaccc
    14581 gggcggcgcg ccgccacagc cgctgccagt cggcggcggc gcggtcgccg aaggccgtgc
    14641 cgatgcgggc ggcgaactcc tccggatcgg cgcaggagtc gagcaccggg ccgccgcccg
    14701 ggaagacgtg ccgcacgatc gggtccagcg gcaccaggtc gaggtactcg tcgagcttgg
    14761 ccccggtcgc ctcgaacagg tcgtggaaga cctggggcag ggtgagcagg ctggggccgg
    14821 tgtcgaagtg gaacgacccc tcggcggtgt cgcgggtgtg ccggccgagc ttgccgccga
    14881 cggtctcggc ccgttccagc acggtcacct gatgtccggt cacggccagc cgggcggcgg
    14941 cggccaaccc gcccaccccg gcaccgatga ccacgatccg cgccatgccg cgccccccta
    15001 gtcgaccgga cggccgcgcc aggacaggcg ccgccgcttg cgcagatggt acgaccgtag
    15061 ggtcagccaa ccgaggaccg cgaccgacac ggggtggccc agcgcgtcgg gccaggcccg
    15121 cccgccggtg gctcgggcgc tgatcacccg cccggccacc ccggtgaggt acgccagccc
    15181 ggcgatcccg gccagcgccg gcgcaccggc cagcagcgcg gccacggcca ccagcggggg
    15241 tgcggtgtag agcacgagca gcagggccac caccagcgcg gcgttgcccg ggtgcccgaa
    15301 cgaggcccag agcgacttgg tgtagccgtc gcgcagctgc ggccagttct cgtacatccg
    15361 gcaggtggcc agccgggagc cgtcggcgag ggcgatccgg ccgccggcgc gtttcaccgc
    15421 ccgggccagc tcgatgtcct ccagcacccg gtcggcgacc gccgcgtgtc cgccggcccg
    15481 caggtagccg gcccggtcca cgaccaggaa ctgcccgccg gccgcggcca gcgacggccg
    15541 ggacgagcgt tccatcgccc gcagcggcag gaaggtcagc cacagccact gcaacagcgg
    15601 ctggaccagc cggtcggccg cggtccgcac cacgatccgg gggtacggcg acagcagggt
    15661 cgccccggcg gcacgcagct cggtgaccgc cgccgccacc gcgtacgggg cgagcaccac
    15721 gtcggcgtcg acgaacacca gcgcgtcggc cgacgccccg acccgggtgg ccagctgcca
    15781 gcaggcgtgc ggcttgccca gccaacccgg cggtggggcg acgccggtga gcagggtgac
    15841 ccgggggtcg ccggcggcca ccgcgcggac cacgtcggcg gtgccgtcgg tcgacccgtc
    15901 gtcgagcacc acgatgcgca gtccgggcac gccccgctgg gcgagcagcg cccgcaggca
    15961 cggggtgacc cgggcggcct cgtcccgcag cggcagcagc accgtcaccg gttcggtgcg
    16021 ggtcaccggc tggtcggtcg gtcggcgcag ccaccggccg gcgttgacca ctgtgtgccc
    16081 ggtcagcacg acgaggaggc cgagcgcggt gagcgaaaac ccgatcatgt ggcggcgtcg
    16141 gccggcggcc ggtccgcctc ggtgctgcgc tccgggggcc gagccggccc ggtgtcgcgg
    16201 tcgcggtgcc ggcgttcccg cagcagcgtg accgccagcg gcacggcgac cagcgccatg
    16261 ccggccgcgc cccacaccgc cgaggcgggc aggtcgagga agaccgcgtg ggccagcacg
    16321 ctgccgccgt acgtccacag gtagagcgcg tacagcgggt ggtcgcgggc gtcggtgtcg
    16381 gccacggcgg gcccggcgag cggacgcagc gcggtcatca ccagcaccgc gaacagcagc
    16441 cagcccaggt agttgctgac cgggatgccg ggcaggccgg gcagtgccgg ttcggcgtcc
    16501 cgccacaccc agtggccctc ggccaccatc tgcgggtcga ggaagagatc ccaggtggcc
    16561 agcccgaggg tggccagcgc gatccgtccc ggccaccgct tgaccagtcg ggtcgccacc
    16621 agccacgccg gccaggccat ccaggtccag gccagcggga tgatcagcgg caccccggcc
    16681 agcttcgggc cgagttgccc ggagtagtcg tagctgccga acgggaagcc ggtggccacc
    16741 ccgagcgcct cgatggctaa cccgccgccg gtggccagcg cgacaagcgc caacgccgta
    16801 cgcgtacccc ggctcagcag cgcgtggccg acggagagca ggtagccgag cacgacggtg
    16861 gccacggtca accgggcccg ggtcgtcccg gcggtcagcg gatagccgat ctgggccagc
    16921 accagcaggg ccagcagcgt ccaggcgtag ccgcgagcca gcctggtcat gaccggtcga
    16981 cgtgctcggg ggcgggcagg ggcaggtccc ggccgagcac cccgaacggg cgctcgtcac
    17041 cggggaagcg gaagtcccgc aggacgtcga cgaagccgaa ccggcggtag agccgccagg
    17101 cgcgggaggt ggcctcgtcg gcctcggggg tggagagcag cacggtcctg ccctcggcca
    17161 tggtgagcag ggcgcgtagt tgcccggcac ccaggccgtg cccctgtgcc gggggtcgta
    17221 cgtgcagctc gaccacttcg aaacagtcgg tcagccagcg ttgccgggcg gccgggtcga
    17281 gcgcccgggc aacctggtcg tgccaccact ggccgggccc gccgaggtag ccgtagccga
    17341 agccggccag gtgaccctcg ctggtcaggc tggcgacggc gcgaaaaccg ggccggcgga
    17401 catgggtggc gatgtagccg cgacgcgcct cgagcaggtc gagccggtag cccatggcct
    17461 cgccgtagac ggccaccacg tcgttcagcc gccgcagcag gtcgtccggc gtccaccgca
    17521 ccagtctcat gcccgctcac ccttcgccgg gtcgccgtcg gcggcccatc ccagtaccga
    17581 ccggtcaccg atcacgtcac gcacctcgaa gcgggcgaag agttcctccg cgtaccaccg
    17641 ctcggtgtcc gtccgggtga tcgcggcccg gtgctccggg tgacggtacg cgaacgccac
    17701 caggtccgcc gggtcacgcc acacgctcac cgtgccctgc cagcccagcg gcgcctcgcc
    17761 gacgccgaag cgggccagca gtccgggcgc ggtgcgcagg gcggcggcga ccggcgggac
    17821 cgcccgccag aaggtgagtg cccgggtcgg ccgcagccgg gcccgggtca gcgccagcac
    17881 cggaccggtg acccgccctc cggtgggctc gccgaacggt cgccggccgg accactcacc
    17941 ccggctggtc agtggccgca ggtcgagccg taccccggcg gtggcgatgc cggaccaggc
    18001 ccggtccacg ggcgagccgg cgaaccgggt cgccgcggcc ggggactccc acaccgtcag
    18061 cgccgcccaa cgggtcgggt cggcgtcgtt cggcccgaaa ccggtgccgg tcccggtgcc
    18121 gagcagcttg ccgaaccgta cgccgggcag ggcgcgcagc cggcgcgggt cgcgggccat
    18181 ccggagcagc acccggggca gcgcgctgcg gggcacccgc cacacgtgca gggtgaccag
    18241 ctccgggacg ttctccagct cgttcacgcc acgtcggtcg gggtgccgcc ggtgacccgc
    18301 agcaactcgg cgtacgtgct ggggaagacc gcctgcggca cgccgccggc ggcccagatc
    18361 tcgtcgtact tgtccagggc ggtgtccacg agcgtgcgca gggggtgcgg gtgacccacc
    18421 ggggcgaccc cgccgatcac ctgcccggtg tgttccttga cgaactgcgg ggtggcgcgg
    18481 cgcagccggg tgaccccgat ccgggcggcc aggccggcgg tgtccacccg gtgcgcgccg
    18541 gaggtgagca ccagcaacgg cgtcccgtcg gcgtcgaaga tgagcgagtt ggcgatggcg
    18601 ccgacgtcga cgccgagcgc ctcggcggcg gccgcggcgg tgtgcaccgc gtcgggcagc
    18661 aggcggaccg tggcggggcc gccggcaccg tcccgggcgt ccacgtcggc gagcgcgtcc
    18721 tgcaccgctc gtacgttggg gtgtgactgc atggcgtcat tcttcccggt acgcgggtga
    18781 tcggcgcagc cggccacggg tgtcgtgagc gggccggaca ccgcagtggt gtcggcgcgc
    18841 cacacgttgc gttttcgccg gcggcagggt gtactgtcag cagcagttag aacgagtgtt
    18901 cgattgcctc gaacgttcgt tccaacctcc tcggggcggt gtttcgcggc accggctccc
    18961 gacaggtgcg gtaccgcgga ccgcaccggg cgccgggcag tcgcgagtcc gggacccgtc
    19021 aggcaggacc gtcgcccgcc gcccacgacc cccgggcggc gggcgacgga cccgccggta
    19081 cgccggccgg gtgtggtgtg gggaagctcc gcacccggcc ggccacccac ctggtgcgtc
    19141 ttcctccgca ccgcccgtca cgggtgcctc gcgcgccgga gcagtcctgc accgcgcgat
    19201 ccacccgcac cggcccacct ggaggagacc catgccgacc agtccggccc ccgcaccgac
    19261 ggtgcccgcg cacgtgctgc cgcaccgcac tcccgcccaa ctgctcacgg tggctcggca
    19321 cggtctcgcc gaggccgccc ggaccggccc cgacggcctg cggtacgccg ccgcccacct
    19381 cgcggcgctg cgcgccgccg ccgcggtgct cgcggcccgc gcccgccccg cgccgacccg
    19441 acgtaaccgc gtcacaagcg tctgggtcct gctcgccacc gtcgcccccg agctggacga
    19501 gtgggccacc tacttcgccc tcggtgccgg caagcgcgcc gccgccgagg ccggcatccc
    19561 ccgggtggtc accgcccggg aggccgacga cctgctccgc gccgccgagg agttcgtggc
    19621 ggtggtggag acggcactcg gcctgacaca tcagccggcc atcgacggtc tcgtcgcctg
    19681 agccgcggcg tccggtgtca cggcgggacc cgggggccgg acgccgcccg gcacgacatc
    19741 tctttccgca ccacatttcc tgcggcacca cgaagatcac catccaccgg ccggggccgg
    19801 tggcgacacg acagggggta ggtccgatgg cgggccgcat ggtggtcggt tccgccgcgt
    19861 tggccgggtt ggtccgcccg gccagcgcac ccgatccggc gggcgggcat cgggtgctgc
    19921 cggtccgttc cgagctgacc gggctgctgc ccggccgtgg gctgcggcgg ggcagcacca
    19981 tcgcggtagg tgccgggcag ctccggtcca gtggcaccac gtcactgctg ttcgccctgc
    20041 tcgccgaggc gtcccaggcc ggttcctggt gtgccgtggt ggggctgccc accttcgggg
    20101 ccggtgcggc ggccgaggcc ggcatcgccc tggaccggct cgcgttggtg ccgcagcccg
    20161 gacccgactg gcccaccgtc gtcgccgcgc tcatcgacgg ggtcgacgtg gtggtcgccg
    20221 ccgtgccggc cactgtctcc gcctcggtcg ccagtcggct ggccgcccgc gcccggcagc
    20281 gcggctgcgt gctcgtgccg tacggccggt gggacggggc ggacgtgatg ctccaggtgg
    20341 tccgcggggt gtgggacggg ctcgggccgg gccggggccg gttgcgccgc cgcgaggtga
    20401 ccatctcggc ccggggccgg ggtgccgccg cccggcccaa ggaggtcaag gtctggctgc
    20461 ctgatgccga actgacccgg atcatccccc ggtcgaccgg ggccggccgg ccgggggccg
    20521 cagggctacg ggtggtggtg tcggcatgag cgggcgtcag cgggcggatc gtcagctcgg
    20581 tgcgcgccag ggtgctccgc tccgaggcgg tcgatcagtg gccgaggtcg gttcgctggg
    20641 ctgggccggc cgaaactgcg gttcgccaga gcgctgtggc gagccagagc agcccggcgc
    20701 cgagcagtac cccgtgggag atccggacca ccgccggggt gaagaactgg ggcaggaaga
    20761 gcaggaaccc gagggcgaac ggcaccccgc tgagtcgggg cagcagattg ccgcgccaga
    20821 tcgccaccgc ggcgagcgcg gcaccggcgc cgagcatcag caggccgatt ccgaaggtgg
    20881 agaccgcgat cgggtcgtac cgcacctggt cggccagggc gagcagatcg agctgtgggt
    20941 tggcggcggc ctggcgggcg atcgcgtgca ggccgaacgc ctcggcgccg tagtacggca
    21001 gcaccagacc ggcgccgatc gtgctggtga cgaaggcggt catggtggtg cggtccgacc
    21061 cggtgccggc gatggcctgg gcg
//
