LOCUS       NZ_AP023358            22129 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Micromonospora endophytica strain NBRC 109090 chromosome, complete
            genome.
ACCESSION   NZ_AP023358
VERSION     NZ_AP023358.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora endophytica
  ORGANISM  Micromonospora endophytica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Jishengella endophytica NBRC 109090
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6586761)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 293x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018326245.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 14:26:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,248
            CDSs (total)                      :: 6,184
            Genes (coding)                    :: 5,715
            CDSs (with protein)               :: 5,715
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 469
            CDSs (without protein)            :: 469
            Pseudo Genes (ambiguous residues) :: 0 of 469
            Pseudo Genes (frameshifted)       :: 323 of 469
            Pseudo Genes (incomplete)         :: 166 of 469
            Pseudo Genes (internal stop)      :: 12 of 469
            Pseudo Genes (multiple problems)  :: 30 of 469
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:19:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2679558
            Orig. end                         :: 2701687
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023358.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22129
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22129
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22129
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12129]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12129
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            426..1298
                     /locus_tag="Jiend_RS12635"
                     /old_locus_tag="Jiend_26210"
     CDS             426..1298
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785433.1"
                     /locus_tag="Jiend_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26210"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_111245942.1"
                     /transl_table=11
                     /translation="MVSGAACVAGLVLAVVAIVGTRRPPGRAPGAGPGISRLWQGSGTA
                     REQRAHQALLVGAFVAGALAFLLTGLPVVGLLVAVAVPGTPWLFSVGRAEQRAIARIEA
                     VGEWTRRLKDVSATGQGLQQAIIGTLPTAPEEIQEEVRLLAARLQAGWLARSALLAFAD
                     EIGDPVCDQVVAALILHLSDRGDRLGDVLGSIASAAAAEVATRREVEAKRTQPRFAVRF
                     LTGMTLATIAYGLLNTEYVQPYGTPLGQVVMAVLGTAFVGLLAWVRSMSQPPRPARFLP
                     APDPREVMA"
     gene            1295..2155
                     /locus_tag="Jiend_RS12640"
                     /old_locus_tag="Jiend_26220"
     CDS             1295..2155
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730907.1"
                     /locus_tag="Jiend_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26220"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_111245936.1"
                     /transl_table=11
                     /translation="MNWLLTVAVTGGAAVGLGVFLVVRELVPATPALGPALRRLHQPAG
                     ARVDPADRRLEWLTGMARWLRPPHRQLALLGRTPEQYALSLLLSALIGLAGPALVSGTL
                     FLVGVSLPLAVPVLGSLGLALLCAFVAHRSVLTRAEVARDEFRQAVCTYLDLVALQLSA
                     AHGPVQSLERAAAICEGWVFDRISEALRMAQMQMHSPWDELRDLADRIGIPELGDVGAI
                     MRSSGSEGAQVHETLRSRADSLRDQIRTDNLARAEGVTSRLDIPGALLVFVLLGFAIYP
                     FLARL"
     gene            2193..2390
                     /locus_tag="Jiend_RS12645"
                     /old_locus_tag="Jiend_26230"
     CDS             2193..2390
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454399.1"
                     /locus_tag="Jiend_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26230"
                     /product="hypothetical protein"
                     /protein_id="WP_111245937.1"
                     /transl_table=11
                     /translation="MSVLIYLHVALRARLAELRGDRGDSPVPTAVIIFGLVAVAMAVTG
                     AALAAANDWMDNIPKHQDPK"
     misc_feature    2425..2439
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            2427..2840
                     /locus_tag="Jiend_RS12650"
                     /old_locus_tag="Jiend_26240"
     CDS             2427..2840
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018738019.1"
                     /locus_tag="Jiend_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26240"
                     /product="TadE family protein"
                     /protein_id="WP_111245938.1"
                     /transl_table=11
                     /translation="MASVIRHRLLPAGSSERGGNPVELAVALPAILVMLFASIQVAVVF
                     VARATALNAAQSGVNAQRLYEAPAGAGEARATKFLNQAGDWLIDWDDPGPSCVTTDTDV
                     TCTVTGKSLSVVPGVDFTIEQSAHGTVERWAAP"
     gene            2825..3292
                     /locus_tag="Jiend_RS12655"
                     /old_locus_tag="Jiend_26250"
     CDS             2825..3292
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730904.1"
                     /locus_tag="Jiend_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26250"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_111245939.1"
                     /transl_table=11
                     /translation="MGRTVSRGSVSIEVAVLAPAFVAMMVLAGVAGRTAVASEALEAAA
                     HDAARAASISRDAGTARQEAREAARRQLDWRGISCAGAPRVTFRGTVGGRSTSFDAAYR
                     SPVGQDASVTVEIACTVSYQDIKLAVLESMPAGNRITVSFTSPLDRYRSRQ"
     gene            3289..3714
                     /locus_tag="Jiend_RS12660"
                     /old_locus_tag="Jiend_26260"
     CDS             3289..3714
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730903.1"
                     /locus_tag="Jiend_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26260"
                     /product="hypothetical protein"
                     /protein_id="WP_111245940.1"
                     /transl_table=11
                     /translation="MSAGRGDAGRVSVFLAVALFGVLAIIGMAFDGAGQLRSLQRAENL
                     AAEAARTGGQAIDLTTAIEGGPKRINKPQARQAVARYLSAAGASGHRVSFPVVDGETLI
                     RVRVTITYRRAVLGLFGFSNTVTVSGEATARALTGTP"
     gene            3730..5052
                     /locus_tag="Jiend_RS12665"
                     /old_locus_tag="Jiend_26270"
     CDS             3730..5052
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018735074.1"
                     /locus_tag="Jiend_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26270"
                     /product="LysM domain-containing protein"
                     /protein_id="WP_119663741.1"
                     /transl_table=11
                     /translation="MAASGGTAVRRIGRVLTGFGALIVLVGLLAGGPIALLAFAGNPLP
                     DHVPALAEIGTTLTSRDDGQLFLRALALVGWLGWVSFAFSVLVELGAQALRRPAPRLPG
                     MSRQQRAAAALVGSVALILATSPAATAATTAYTAGAWAGAPTTAAAAGSPSAAAAGSAA
                     MSTARAQALAAPAVGPAGMVAAGAAGPVTADRDDDRAEAPVYRVAKGDYLGKVAERYLD
                     EFGDYRELAALNRLRDPDRIRPGQLITLPTEAADQGSRAHATGRLVARVAPPSSPSPAA
                     PERTESRKPSPSPSGSPTPQPGSPTPQPGGSSSQPGGPAQEPGGSTQQPDGSTQEPGGR
                     GSLTPVGPGPQGGEHAPPRGDAPGGHPPVVTVGAASASEPDRVNRPLAVSAVLAVASII
                     GAQIGAVLGMRRRPAAARVGGRRHVPVSPPSELPIGRHRRY"
     gene            complement(5297..6148)
                     /locus_tag="Jiend_RS12670"
                     /old_locus_tag="Jiend_26280"
     CDS             complement(5297..6148)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785440.1"
                     /locus_tag="Jiend_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26280"
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="WP_111246624.1"
                     /transl_table=11
                     /translation="MRALLTKIEQASGLDRFGDRLQGVVQGILRPQRVRDLLHGVWLGH
                     PLHPAMVQVPVGSWISAAVLDLMPGQRRAATTLTAVGTLSAVPAAVAGLNDWAALSRDQ
                     RRIGLVHAAANTVALAMYGGSVAARLSGRHQLGRTLGWLGLSAAGAGAYIGGHLAYKQG
                     AQVNVSVSDLHLISDGWHPIAELTKLPQRELVTHKVDDVSVIVYRHGDDVTVMLERCPH
                     QSGPLGEGEVREIDGHACVVCPWHGSTFRLNGGEVVHGPSPNDQQILPTRIVDGQLETR
                     LP"
     misc_feature    complement(6123..6136)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            6325..7086
                     /locus_tag="Jiend_RS12675"
                     /old_locus_tag="Jiend_26290"
     CDS             6325..7086
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (5-221). E-value: 4.7e-41. Score:
                     132.6. Matches aSDomain:
                     nrpspksdomains_Jiend_RS12675_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF006108.0"
                     /locus_tag="Jiend_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26290"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_119663742.1"
                     /transl_table=11
                     /translation="MAVRVERDGPVTTVILDRPAVRNAVDGPTARALADAFRSFEADPD
                     ASVAVLWGAGGTFCAGADLKAIGTPSGNRVEPDGDGPMGPTRMVLSKPVIAAISGHAVA
                     GGLELALWCDLRVAESDAVLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVP
                     ADEAYAMGLVNRLVGPGESRAAAERLAAEIAGHPQTCLRNDRAAVLATAHQPEPEALTI
                     ELTYGLHSLATDTPHAPTLFATRRTPADLGT"
     aSDomain        6340..6987
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Jiend_RS12675_ECH.1"
                     /evalue="4.70E-41"
                     /label="Jiend_RS12675_ECH.1"
                     /locus_tag="Jiend_RS12675"
                     /protein_end="221"
                     /protein_start="5"
                     /score="132.6"
                     /tool="antismash"
                     /translation="ERDGPVTTVILDRPAVRNAVDGPTARALADAFRSFEADPDASVAV
                     LWGAGGTFCAGADLKAIGTPSGNRVEPDGDGPMGPTRMVLSKPVIAAISGHAVAGGLEL
                     ALWCDLRVAESDAVLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVPADEAY
                     AMGLVNRLVGPGESRAAAERLAAEIAGHPQTCLRNDRAAVLATAHQPEPEALT"
     misc_feature    complement(6344..6359)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(7151..8629)
                     /locus_tag="Jiend_RS12680"
                     /old_locus_tag="Jiend_26300"
     CDS             complement(7151..8629)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454372.1"
                     /locus_tag="Jiend_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26300"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_111244402.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-48, bitscore:
                     164.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPELVDVVVLGLGVGGEEVAGRLAEAGLSVVGIERNLVGGECP
                     YWGCIPSKMMIRAANAIAEARRVDGLAGTAQVHPDWTPVAKRIRDEATANWDDTAAVRR
                     FTDKGGRFVRGSGRFDGPARVRVGEQVFQARHGIVLGTGTKATVPPIDGLADTPYWTNR
                     EAIEVEELPESLLVLGGGAIGLELAQVFARFGVRVTVLEASERVLLVEEPEASEAVAAA
                     LRADGVQIQTQVKAARIEHDADGFTLRGAGGEEFTADRLLVATGRRAHLDELGLDTIGV
                     DAGRRYLSVDDRLHVTDGVWAVGDVTGEGAFTHVAMYQAAIVVADVLDHARRADPGADP
                     SGTASVVGGAVGAASALAATGASGSAGSVPRADYRALPRVTFTDPEIGAVGLTERQARE
                     RGINVQIGFSKLSSNTRGWIHKTDEGGFIKLIADADQGVLIGATSAGPAGGEVLSGLVV
                     AVHAAVPLTQLRHMIYAYPTFHRAISEALRNLPS"
     gene            complement(8685..10004)
                     /locus_tag="Jiend_RS12685"
                     /old_locus_tag="Jiend_26310"
     CDS             complement(8685..10004)
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283453.1"
                     /locus_tag="Jiend_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26310"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_111244399.1"
                     /transl_table=11
                     /translation="MTGRTGIVLFTRDLRVHDHPALATSCAAFDRVVPLYVLDPALAQL
                     SPNRTRFLHQSLAALRAALRGLGGDLVLRHGDPVAETIRLAGEVGAEGIALSADVSRYA
                     ERRATRLRAECERHRLHLRFFPGLTVVDPGALRPTGGDHYRVFSPYHRAWSAHRWRDEL
                     GPPARVTLPAQVPVGRLPAVPAGDSPEAVPGGEDEAWRRLTTWLPAVPHYGDRHDDLAG
                     DGTSRLSPYLRFGCLSPLTVANRADRDSPFVRQLCWRDFYHQVTAAFPDISRRAYRRGA
                     TEHWRYADDTLAAWQQGRTGLPIVDAGMRQLRAQGWLHNRARLITAGYLTKTMGLDWRD
                     GVAVYFRWLLDGDVANNSGNWQWVAGTGNDTRPYRGFNPIRQAERYDPDGAYVRRWVPE
                     LATVPGAAVHQPWRLPTALRRTLDYPSPLEVPGPEPVWLR"
     gene            complement(10001..10912)
                     /locus_tag="Jiend_RS12690"
                     /old_locus_tag="Jiend_26320"
     CDS             complement(10001..10912)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015633.1"
                     /locus_tag="Jiend_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26320"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_111244398.1"
                     /sec_met_domain="phytoene_synt (E-value: 7e-113, bitscore:
                     374.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.9e-64,
                     bitscore: 214.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQDLAAAYGRCRELHKRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDQTEALPPAERAAQLDDWGGRFVAGLHGEPVDDPLLPAVLHTIAVFDLDRED
                     FATFLKSMTMDLTVSSYRSYGQLVDYMEGSAAVIGTMMLPILGSSDPSAAREPARQLGF
                     AFQLTNFIRDVAEDLDRGRTYLPVDDLAAFGVTADDLAACRAAGRATEAVRELIRHEVG
                     RAQAHYAAAAPGVTLLDAGSQACIRTAYALYGGILDEVAAQDYDVFVRRATVPQRRRMA
                     VASRALLTPTGTPVALPGPPLP"
     misc_feature    complement(10790..10792)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10944..10956
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    10959..10977
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            10978..12129
                     /locus_tag="Jiend_RS12695"
                     /old_locus_tag="Jiend_26330"
     CDS             10978..12129
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="Jiend_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26330"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_111244397.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.1e-49, bitscore:
                     165.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDELTGNLLRVAPDQSIDEDDPIQAVLAAYTRDLGTAIDRILA
                     EFLTPEVDSLREIDAAMGDFAATARDCVLAGGKRVRSTFAYWGWRGVVGADQPVDPVLP
                     ALATLELLHTFALVHDDVMDASALRRGRPTAHVAVASRHAAAGRNGNSDRFGEAVAVLI
                     GDLCMVWADQLLARTALPAPQLMQVRRGYDRMRVETIAGQYLDVLGETDPSNWSVDRAL
                     RVARYKTASYTVQRPLLFGASLCGADDATVITAYTRYGRSVGEAFQLRDDLLGVYGDPL
                     TTGKPAGDDLRTGKPTALLMLARQLASPAQRRALAGTGPHVTESAVAQLAEVVRDTGAV
                     DRIERMIDERIEDALATLDALTIDETARTALVGLATAAARRSA"
     misc_feature    11140..11142
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12160..13641
                     /gene="crtI"
                     /locus_tag="Jiend_RS12700"
                     /old_locus_tag="Jiend_26340"
     CDS             12160..13641
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454362.1"
                     /locus_tag="Jiend_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26340"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_111244396.1"
                     /sec_met_domain="DAO (E-value: 4.9e-18, bitscore: 64.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVDGRTDRVVVVGAGLGGLACALHLAGSGRQVTLLEREPVPGG
                     RAGRLSVDGYEFDTGPTVLTMPDLIAEALGAVGEELTDWVDLIPLDPAYRAYYPDGSTL
                     DVLTDTTRMAAEISRVCGPQEADGYLRFVDFARELWRLERADFIERNLDAPTDLLTANL
                     LRLLANGAFRRLQTKIDQFFRDPRTRRIFSFQAMYAGLAPHDALAIYAVIAYLDSVAGV
                     YFPRGGIHAVSRGLAGAAEKHGVQIRYGTTVTQVVTANGRATGVLTADGEFVPADVVVL
                     NPDLPVAYRDLLPPSRPRRLTYSPSCVVLHVGSTQGYRRIAHHNIHFGRAWKGTFDEVI
                     RRGELMTDPSLLVTNPSRTDPAVAPADRHTYYVLAPVPNLDRAPFDWRGDLTQRYTDQL
                     INTLEQRGYLGFGAGVEVLRAVTPAEWAEQGMAAGTPFASAHTLFQTGPFRPSNMHRSL
                     SNVVFVGSGTQPGVGVPMVLISGKLAASRVTGEGK"
     gene            13697..14253
                     /gene="idi"
                     /locus_tag="Jiend_RS32425"
                     /pseudo=""
     CDS             13697..14253
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730891.1"
                     /locus_tag="Jiend_RS32425"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPSREAHLVELVDDAGHAVGETTVAAAHRPPGQLHRAFSVLLVA
                     PDGRMLLQRRAAAKTRFPLRWANSCCGHPCRVSRSPRPRIGGSRRSWGPARCH"
     gene            14243..15190
                     /locus_tag="Jiend_RS12710"
                     /old_locus_tag="Jiend_26360"
     CDS             14243..15190
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283448.1"
                     /locus_tag="Jiend_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26360"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_111244394.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSQHVPGHHRRYT
                     PADLARLEIMLRLTSEGVSPAEAARWARQVPGTPPDGTAVRARPRSFRDGGGTAIPVGR
                     AGPAARGLARAAMRLDALAITETVTRAIATDGVVRTWDRLLRPVLVGIGERHAATGSLI
                     EVEHLLSRCVSAAFAAIVTARPAPAGPPRILLSCADEEQHSLPLEALAAALAEAGVNHR
                     MLGARVPVTALLDAIDRTGPAAVVVWSHLRFTADASQLTALLTAPRRPLLVLAAGPGWQ
                     ADNLPAGVVRPVDLAEALSLAVAVRDSLDRSAAS"
     gene            15343..16128
                     /locus_tag="Jiend_RS12715"
                     /old_locus_tag="Jiend_26370"
     CDS             15343..16128
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730889.1"
                     /locus_tag="Jiend_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26370"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_111244393.1"
                     /transl_table=11
                     /translation="MRSRLLLACATGLAVLLVSGCAGTGPPDTSPPASPPPSAALPPQA
                     TPAPTRTTPPKPRLRALPAKLPAGLVRTTGNAKVALTFDDGPDPAWTPKVLDRLKKAKV
                     TATFCVVGTQVRKHPELVRRIVREGHQLCNHSWNHDLDLARRPIAEIRADLVRTNKEIR
                     RAVPDAEVPFYRQPGGRWTAEVVKVARKLDMRSLHWTVDPQDWAKPTAATIAKRVKRTA
                     KPGAVVLLHDGGGDRAATLAACSRVITALKRDHGIVRLR"
     misc_feature    complement(15345..15356)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     tRNA            16283..16355
                     /anticodon=(pos:2695875..2695877,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Jiend_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Jiend_t00250"
                     /product="tRNA-Glu"
     gene            16283..16355
                     /locus_tag="Jiend_RS12720"
                     /old_locus_tag="Jiend_t00250"
     tRNA            16389..16462
                     /anticodon=(pos:2695981..2695983,aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Jiend_RS12725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Jiend_t00260"
                     /product="tRNA-Asp"
     gene            16389..16462
                     /locus_tag="Jiend_RS12725"
                     /old_locus_tag="Jiend_t00260"
     tRNA            16563..16636
                     /anticodon=(pos:2696155..2696157,aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Jiend_RS12730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Jiend_t00270"
                     /product="tRNA-Phe"
     gene            16563..16636
                     /locus_tag="Jiend_RS12730"
                     /old_locus_tag="Jiend_t00270"
     misc_feature    complement(16655..16672)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.81"
                     /tool="antismash"
     gene            16763..17275
                     /locus_tag="Jiend_RS12735"
                     /old_locus_tag="Jiend_26380"
     CDS             16763..17275
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018829525.1"
                     /locus_tag="Jiend_RS12735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26380"
                     /product="SRPBCC family protein"
                     /protein_id="WP_111244392.1"
                     /transl_table=11
                     /translation="MGHGMADATEVTQDHDRFALRSTLLVPTPAERAYEVFTGNIADWW
                     VTEYTWSGPGALAELGMEPRAGGMLYEIGPYGFRNDWGRVVIWDPPRRLVFTWQIGADR
                     VPVPDPARASEVEVLFTSAGSGTLVEVTHRHFDRHGEAAEGYREALTAGWHELLSRFAA
                     TVTDRLT"
     misc_feature    16783..16798
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            complement(17319..17708)
                     /locus_tag="Jiend_RS12740"
                     /old_locus_tag="Jiend_26390"
     CDS             complement(17319..17708)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730887.1"
                     /locus_tag="Jiend_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26390"
                     /product="hypothetical protein"
                     /protein_id="WP_111244401.1"
                     /transl_table=11
                     /translation="MTDSPQQMLDDANAILRSALDGDSEAVTGTFDAVVDRDGLAGAYG
                     VAWCLAATMVGDPVPSGTCALDFPGIEQAEYDARWVARFVSAYANADLDTAEALFGAAA
                     ADGLLPECLLTLAGSAVATLRHRAS"
     gene            17863..19205
                     /locus_tag="Jiend_RS12745"
                     /old_locus_tag="Jiend_26400"
                     /pseudo=""
     CDS             17863..19205
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730886.1"
                     /locus_tag="Jiend_RS12745"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26400"
                     /product="ABC transporter substrate-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHMSRGSRTAALAACAALLLATSACGDDQAEEATTQQVRLYGTDG
                     NMSNSYADELEDRASLVDGMKGTTPLTPLPEDFKKRLLSVDPQLDGFLYAAEAYDAVVI
                     STLAAEIAGTTDPAAIAKQIVGVTNDGTSCGSPAQCLRLIRDGRDIEYRSVSITRAGFT
                     DAGEPATASYATLHFDGERLNDAKTEFVGAGDESAASSKAPPRVNRPAGAGNGPLVIGG
                     LLPKTGDLALAYPPLAAGTALAIKEINDAGGVLGEDVVWVDGDDGTNPTVAKATVARHI
                     DAGVHVIIGAGGSGISAAVLEDVVQGGRILFSPSNTAASLTNADDNGLYFRTARRTVSR
                     AGRWPTSSSGTVRRRSRSWPVRIPTARASRTSSAPSWSGPVSAATR"
     gene            complement(19264..20009)
                     /locus_tag="Jiend_RS12750"
                     /old_locus_tag="Jiend_26420"
                     /pseudo=""
     CDS             complement(19264..20009)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454342.1"
                     /locus_tag="Jiend_RS12750"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26420"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSTGLRIEERADRLVVTLDRPEKRNAIDADLIAALHDVCAELEAR
                     PGCCC"
     gene            complement(20006..20899)
                     /locus_tag="Jiend_RS12755"
                     /old_locus_tag="Jiend_26440"
     CDS             complement(20006..20899)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730884.1"
                     /locus_tag="Jiend_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26440"
                     /product="3-hydroxyacyl-CoA dehydrogenase family protein"
                     /protein_id="WP_111244389.1"
                     /transl_table=11
                     /translation="MTERFVVVGAGTMGLGIAYVAAEAGHLVELVEVDRARGDAAVARL
                     AQLWEGAVRRGKATAEQATASRQRVTLRAGLAEVAAEPDVIVEAVPERLDLKRAVLIEA
                     EALRPLLLGSNTSSIPITELADGLTRPERFCGLHFFNPVWAMTLLEIVVGPATAAETTD
                     AARTLAARLGKDPVVVRDMPGFATSRLGVALGLEAIRMVADGVASPADIDKAMALGYRH
                     PVGPLELTDLVGLDVRLDIARTLQAAYGDRFAPPSLLVEMVAAGRLGKKSGQGFYSWAD
                     GVRAGGIESPEPGAVR"
     misc_feature    21057..21068
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            21094..21390
                     /locus_tag="Jiend_RS12760"
                     /old_locus_tag="Jiend_26450"
     CDS             21094..21390
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283434.1"
                     /locus_tag="Jiend_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Jiend_26450"
                     /product="hypothetical protein"
                     /protein_id="WP_111244400.1"
                     /transl_table=11
                     /translation="MSQAPETAGHAGTEETVETRGDERIDLLRADTNNDGRTDVWVVDT
                     DGDGKADLFQFDTDGDGKVDVTMVDLDEDGQPDEIVDGDGGLPPEQLPPTVQV"
     misc_feature    complement(21618..21633)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    complement(21705..21718)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.62"
                     /tool="antismash"
ORIGIN
        1 cccgtacccc cgccggggtg agcgaacgga tcatcgagct ggcgttggcg cacggccggg
       61 agatgactgt cgaccaggcc cgccggatgg ccggcaacgc gctcgacctc atcgtctacg
      121 tcaccgtcga ggacgagacc ggcatcggcg ggcgcaagca ccggtacgtc tcgcacgtcg
      181 aggaggtgct cggcgtcagc gagggcagcc ggatcaccac cacgcaggtg ttcgggccgg
      241 gtccggacgg ccgggcggtg ccgcgacacc tgcccgagcg ggtccgggac caactgctgc
      301 gggtgggcta cgacgcgcgg ctgctgagcc gctggatcga ggccggtcag ggcgcctggc
      361 gccgacccaa acagacccga ctcggtcggc ggtgagtggt gcgcaacgac atcgaactga
      421 tcgcgatggt ctccggggcc gcctgcgtgg ccgggctggt gctggccgtc gtcgcgatcg
      481 tcggcacccg tcgcccaccc ggccgggctc ccggcgcggg gccgggcatc agccggctct
      541 ggcagggctc cggcaccgcc cgggagcagc gggcacatca ggcgctgctt gtcggtgcgt
      601 ttgtcgccgg ggcgctggcc ttcctgctga ccggtctgcc ggtggtcggt ctgctggtcg
      661 cggtggcggt acccggcacg ccgtggctgt tctccgtcgg ccgggccgag cagcgggcca
      721 tcgcccggat cgaggcggtc ggcgagtgga cccgccgact caaggacgtc tcggccaccg
      781 gtcagggtct ccagcaggcg atcatcggca ccctgccgac cgcgccggag gagatccagg
      841 aggaggtacg gctgctcgcc gcccggctcc aggcaggttg gctggcccgc tccgccctgc
      901 tcgccttcgc cgacgagatc ggcgacccgg tctgcgacca ggtggtcgcc gcgctcatcc
      961 tgcacctcag cgaccggggt gaccgcctcg gtgacgtact cggctcgatc gcgtcggcgg
     1021 cggcggccga ggtcgccacc cgccgggagg tcgaggccaa acgcacccag ccacggttcg
     1081 cggtccgctt cctcaccgga atgaccctgg ccaccatcgc gtacgggctg ctgaacaccg
     1141 agtacgtcca gccgtacggc acaccgctcg gccaggtggt gatggcggtc ctcggcaccg
     1201 ccttcgtggg cctgttggcc tgggtgcgct cgatgagcca gccaccccgg ccggcccggt
     1261 tcctgcccgc ccccgatccg cgcgaggtga tggcgtgaac tggttgctga cagtcgccgt
     1321 caccggcgga gccgccgtcg ggctgggcgt gttcctggtg gtccgcgagc tggtgccggc
     1381 gactccggcc ctcggcccgg cgttgcgccg cctgcaccag ccggcggggg cccgggtcga
     1441 tcccgccgac cgccgcctgg agtggctcac cggcatggcc cgctggctgc gccccccgca
     1501 ccggcaactg gccctgctcg gccgcacccc cgagcagtac gcgttgtccc tgctgctgtc
     1561 ggccctgatc ggcctcgccg ggccggccct ggtcagcggc accctgttcc tggtcggggt
     1621 cagtttgccg ctggccgtgc cggtgctggg cagtctcggg ctggcgctgc tctgtgcctt
     1681 tgtcgcgcac cgttcggtgc tcacccgcgc cgaggtggcc cgggacgagt tccgccaggc
     1741 ggtctgcacc tatctggatc tggtcgcgct gcaactctcc gccgcgcacg gtccggtgca
     1801 gtcgctggag cgggccgcgg cgatctgtga gggctgggtc ttcgaccgca tctccgaggc
     1861 gttgcgcatg gcccagatgc agatgcactc gccctgggac gagctgcgtg acctggccga
     1921 ccggatcggc atcccggaac tgggtgacgt cggggcgatc atgcgctcct cgggcagcga
     1981 gggcgcgcag gtgcacgaga ccctgcgcag ccgggccgac tcgctgcgcg accagatccg
     2041 caccgacaac ctggcccggg ccgagggggt gaccagccgc ctcgacatcc ccggcgcgct
     2101 gctggtcttc gtcctgctcg gcttcgccat ctatccgttc ctggcccgcc tctgacctcc
     2161 ctcctcccct cccagagcaa aggagcaccc cgatgtccgt cctcatctat ctgcacgtcg
     2221 cgctgcgtgc acggctggcc gagctgcgtg gcgatcgggg cgacagccca gtgccgaccg
     2281 cagtgatcat ctttggcctg gtggccgtgg cgatggcggt gacaggtgcc gcgctcgccg
     2341 ccgccaacga ctggatggac aacatcccga agcatcagga cccgaagtga gccatgcctg
     2401 acgcccggtc caccggatgg tgccggatgg cctcggtcat ccggcaccgc ctgctgcccg
     2461 ccggttcctc ggagcggggc ggcaacccgg tggagttggc ggtggcgctg ccggcgatcc
     2521 tggtgatgct cttcgcctcg atccaggtcg ccgtggtgtt cgtggcccgc gccaccgcgc
     2581 tcaacgccgc ccagagcgga gtcaacgcgc agcggctcta cgaggccccg gcgggtgccg
     2641 gtgaggcgcg ggccacgaag ttcctcaacc aggccgggga ctggctgatc gactgggacg
     2701 acccggggcc gagctgcgtc accaccgaca ccgacgtgac ctgcacggtc accggtaagt
     2761 ccctctccgt cgtaccaggg gtcgacttca ccatcgagca gagcgcacac gggacggtgg
     2821 agcgatgggc cgcaccgtga gccggggctc ggtctcgatc gaagtcgccg tcctggcgcc
     2881 cgccttcgtg gcgatgatgg tgctggccgg agtcgccggc cgtaccgccg tggccagtga
     2941 ggcgctcgag gccgccgcgc acgacgccgc ccgggccgcg tcgatctccc gggatgccgg
     3001 cacggcccgg caggaggccc gggaggcggc ccgccggcag ctggactggc gcgggatctc
     3061 ctgcgccggt gcgccccggg tgaccttccg ggggacggtc ggcggccggt ccacaagctt
     3121 cgacgcggcc taccgcagcc cggtggggca ggacgcctcg gtcaccgtgg agatcgcctg
     3181 cacggtgtcc taccaggaca tcaagcttgc ggtcctggag agcatgccgg cgggcaaccg
     3241 gatcaccgtg tcgttcacct ctcccctgga ccgctaccgg agccggcaat gagcgcggga
     3301 cgcggcgacg ccgggcgagt gagtgtcttc ctcgccgtcg cgctcttcgg cgtactcgcg
     3361 atcatcggca tggcgttcga cggcgcgggc cagctccgca gcctgcaacg cgccgagaac
     3421 ctggccgccg aagcggcccg gaccggcggc caggccatcg acctgaccac cgcgatcgag
     3481 ggcggaccca agcggatcaa caagccccag gcccgacagg ccgtcgcgcg gtatctctcc
     3541 gccgccgggg ccagcggcca ccgcgtgagc ttcccggtgg tcgacggcga gaccctgatc
     3601 cgggtacgcg tcaccatcac ctaccgccgg gccgtactcg gcctcttcgg cttctccaac
     3661 accgtcaccg tctccggtga ggcgaccgcg cgggcgctga ccgggacacc ctagggaagg
     3721 aaggtggcca tggccgcatc gggtggcacc gccgtacggc ggatcggccg ggtgctgacc
     3781 ggcttcggtg cgctcatcgt gctggtcggc ctgctggccg gcgggcccat cgcgctgctg
     3841 gccttcgccg gcaacccgct accggatcac gtgccggcgc tggcggagat cggcaccacg
     3901 ctcaccagcc gcgacgacgg gcaactcttc ctgcgcgcgt tggcgctggt cgggtggctc
     3961 ggttgggtct cgttcgcctt ctccgtgctg gtggagctgg gcgcgcaggc gctgcgccgg
     4021 ccggcgcccc ggctgcccgg gatgagccgg cagcagcgcg ccgccgcggc gctcgtcggg
     4081 tcggtggccc tgatcctggc caccagtccg gccgccaccg ccgccaccac ggcatacacc
     4141 gccggcgcct gggccggcgc accaacgacg gctgcggcgg ccggctcgcc gtcagctgcg
     4201 gcggctggct cggcggcgat gtctacggcg agggcacagg cgttggcggc tccggcggtg
     4261 ggcccggccg ggatggtggc tgccggggca gcgggcccgg tgacagcgga tcgggacgat
     4321 gaccgggctg aggccccggt ctaccgggtg gccaagggtg actacctcgg caaggtggcc
     4381 gagcggtatc tcgacgagtt cggggactac cgggagctgg ccgccctcaa ccgactgcgt
     4441 gacccggacc ggatccgccc cggccagctc atcacgctgc cgaccgaggc ggcggaccag
     4501 ggttcccggg cacacgccac cggtcgcctg gtcgcccggg tggccccgcc ctcctcgccg
     4561 agcccggccg cgccggagcg gaccgagagc cgcaaaccgt cgccgtcacc atccggcagc
     4621 cccaccccgc aacccggcag ccccaccccg cagcccggcg gctccagctc ccaacctggc
     4681 ggcccagcgc aggagcccgg cggatccact cagcagcctg acggctcgac gcaggagccc
     4741 ggcgggcgcg gctcgctcac acctgtgggg cccggaccgc agggcggcga acacgcaccg
     4801 ccacgcggcg atgcgccggg cggccacccg ccggtggtga ctgtgggtgc ggcgagcgcc
     4861 agcgaacccg accgggtcaa ccgcccgctc gcggtctccg cggtgctcgc cgtggccagc
     4921 atcatcggcg cgcagatcgg tgccgtactg ggcatgcgtc gtcgcccggc ggcggcccgc
     4981 gtcggcggac ggcggcacgt cccggtcagc ccaccgtcgg aactgccgat cggccgccac
     5041 cgccgctact gacaccgccg ccgcaccgag gaccgttcaa tccctcccag gcgacctcaa
     5101 gcgcctctgt tgccccggtc cacccacgac gggtgccggg gcaatacgca gcccggccgt
     5161 catcacgaag gctggttgga cccggcctcg gtagcagttt cagggaaagt gctgtctcgc
     5221 tggctgatgg ctgacgaggc agcactttcc ctgaacttgt gcggatcttg accgtgccgg
     5281 gcgggtccgg cgacggtcag ggcaggcggg tctccagctg gccgtcgaca atccgggtcg
     5341 gcaggatctg ctggtcgttg ggggacggcc cgtgcaccac ctcgccgccg ttgaggcgga
     5401 acgtgctgcc gtgccatggg cacaccacgc aggcgtgtcc gtcgatctcg cgtacctcac
     5461 cctcgccgag tgggccgctc tggtgcgggc agcgttcgag catcaccgtg acgtcgtcgc
     5521 cgtgccggta gacgatcacc gacacgtcgt ccaccttgtg ggtgacgagt tcccgctgcg
     5581 gcagcttggt cagctcggcg atcggatgcc agccgtcgct gatcaggtgc aggtcggaaa
     5641 cgctcacgtt cacctgggca ccctgcttgt acgccaagtg cccaccgatg tacgcccccg
     5701 caccggcggc gctcagcccg agccagccga gcgtacgccc gagttggtgt cggccggaca
     5761 accgcgcggc caccgagccg ccgtacatcg ccagcgcgac ggtgttcgcc gcggcgtgca
     5821 ccagtccgat ccggcgttgg tcccgggaca gtgcggccca gtcgttcaac ccggcgaccg
     5881 ccgccggcac cgcgctcagc gtgccgaccg cggtgagcgt ggtggccgcc cggcgctggc
     5941 ccggcatcag gtccagcacg gctgcgctga tccaggaccc gaccggcacc tgcaccatcg
     6001 ccgggtgcag cgggtgcccg agccagaccc cgtgcagcag atcccggacc cgctgcggac
     6061 ggaggatgcc ctgcaccaca ccctgcaacc ggtcaccgaa ccggtccagg ccggaagctt
     6121 gctcgatctt cgtcaacaag gctcgcacgg ctaccaactt cccgccgggt ccgacggcaa
     6181 accggtcgtc cgggacgaat caccaggcaa gggccgagtt cacccgttcg gacggccggc
     6241 caccgctccc gcccgcctca gccggagacg ggcctgacga gaccccgggc gacctgatgc
     6301 gccgggcacc ggcatcctga tgggatggcg gtacgggtgg aacgggacgg accggtgacc
     6361 acggtgatct tggatcgacc ggcggtacgc aacgcggtcg acgggcccac cgcacgcgct
     6421 ctggctgacg cgttccggtc cttcgaggcc gatccggacg cctcggtggc ggtgctctgg
     6481 ggagccggcg gcacgttctg cgcgggtgcc gacctcaaag ccatcggtac gcccagcggc
     6541 aaccgggtcg agccggacgg cgacggcccg atgggcccca cccggatggt gctcagcaag
     6601 ccggtgatcg ccgcgatctc cggccacgcc gtggccggtg ggctggagtt ggcgctctgg
     6661 tgcgatctgc gggtcgccga gtcggacgcg gtgctcgggg tcttctgccg gcgctggggc
     6721 gtgccgttga tcgacggcgg cacggtgcgg ctgccgaggc tgatcggcga gagccgggcg
     6781 atggacctga tcctcaccgg ccgtccggtg ccggccgacg aggcgtacgc catggggttg
     6841 gtcaaccggc tggtcggccc gggtgagtca cgcgcggcgg ccgagcggct ggccgccgag
     6901 atcgccggcc acccgcagac ctgcctgcgc aacgaccgcg ccgccgtgct ggccaccgcc
     6961 caccaacccg aacccgaggc cctcaccatc gaactcacct acggcctgca ctccctcgcc
     7021 accgacaccc cccacgctcc caccctcttc gctacccgcc gcacccccgc cgaccttggt
     7081 acgtaatggc ccctccgagg gcccccaggg ccgaaatcgt ccaagatctc aaagcagggg
     7141 aggtaacggg ctaggagggc aggttgcgga gggcttcgga gatggcgcgg tggaaggtgg
     7201 ggtaggcgta gatcatgtgc cggagctggg tcagcgggac cgccgcgtgc acggccacca
     7261 ccagcccgga gagcacctcg ccgccggccg gcccggcgga ggtggccccg atcaggacgc
     7321 cctgatcggc gtcggcgatc agtttgatga agccgccctc gtcggtcttg tggatccagc
     7381 cccgggtgtt cgaggagagc ttcgagaaac cgatctgcac gttgatgccg cgttcccggg
     7441 cctgccgctc ggtcaggccg accgcgccga tctcggggtc ggtgaaggtg acccggggca
     7501 gcgcccggta gtcggcgcgc ggcaccgatc cggccgagcc gctggcgccg gtggccgcca
     7561 acgcgctggc cgcgccgacc gcgccgccca ccacgctggc ggtgccgctg ggatccgcgc
     7621 cggggtcggc gcgccgggcg tggtcgagca cgtcggcgac gacgattgcc gcctggtaca
     7681 tggccacgtg ggtgaaggca ccctcgccgg tcacgtcgcc gaccgcccag acgccgtcgg
     7741 tgacgtgcag ccggtcgtcg accgagaggt agcgccgacc ggcgtccacc ccgatcgtgt
     7801 ccagtcccag ctcgtccagg tgggcgcggc gtccggtggc caccagcagc cggtcggcgg
     7861 tgaactcctc gccgccggcc ccgcgcaggg tgaagccgtc ggcgtcgtgc tcgatccgcg
     7921 cggccttgac ctgggtctgg atctgcacgc cgtcggcccg caacgcggcg gcgaccgcct
     7981 cggacgcctc cggctcctca acgaggagca cgcgttccga cgcttccagc accgtgaccc
     8041 gtacgccgaa gcgggcgaac acctgggcca gctccagccc gatcgcgcca ccgcccagca
     8101 ccagcagcga ttccggcagt tcctcgacct cgatggcctc gcggttggtc cagtacggcg
     8161 tgtcggccag cccgtcgatc ggcggcaccg tcgccttggt gccggtgccg agcacgatcc
     8221 cgtgccgggc ctggaacacc tgttcgccga cccgcacccg agctggcccg tcgaaccggc
     8281 cgctgccccg cacgaagcgc ccacccttgt cggtgaagcg ccgcaccgcg gcggtgtcgt
     8341 cccagttggc ggtggcctcg tcgcggatcc gtttcgccac cggcgtccag tcggggtgga
     8401 cctgcgcggt gccggccagc ccgtcgaccc ggcgggcctc ggcgatcgcg ttcgccgccc
     8461 ggatcatcat cttgctcggg atgcagcccc agtacgggca ctccccgccg accaggttcc
     8521 gctcgatgcc gaccacgctg agcccggcct cggcgagtcg cccggccacc tcctcgccgc
     8581 cgaccccgag cccgagcacg accacgtcca ccagttccgg ctccgtcatg ctgacagcat
     8641 cgcgtaccgt cccgccgtcg gccacacgcc ttccgggtcc agggtcagcg cagccagacc
     8701 ggttccgggc cgggcacctc cagtggcgac gggtagtcga gggtgcgccg cagcgccgtc
     8761 ggcaggcgcc acggctggtg caccgccgcg cccggcaccg tggccagttc cggcacccag
     8821 cgccgcacgt acgcgccgtc cgggtcgtat cgctcggcct ggcggatcgg gttgaatccc
     8881 cggtacggcc tggtgtcgtt gccggtgccg gcgacccact gccagttgcc tgagttgttc
     8941 gccacgtccc cgtccagcag ccagcggaag tagaccgcca ccccgtcccg ccagtccagg
     9001 cccatcgtct tggtcaggta gccggccgtg atcagccggg cccggttgtg cagccagccc
     9061 tgtgcccgca actgccgcat cccggcgtcc acgatgggca gtccggtgcg tccctgctgc
     9121 cacgcggcga gcgtgtcgtc ggcatagcgc cagtgctcgg tggcgccccg ccggtacgcc
     9181 ctgcgggaga tgtccgggaa ggcggcggtg acctggtggt agaagtcccg ccagcagagt
     9241 tgccgcacga acggcgagtc gcggtcggcc cggttcgcca ccgtcagtgg ggagaggcag
     9301 ccgaagcgca ggtaggggct gagccgggag gtgccgtcac cggccaggtc gtcgtgccgg
     9361 tcgccgtagt gcggcacggc cggcagccag gtcgtcaacc gacgccacgc ctcgtcctcg
     9421 ccaccgggga cggcctccgg cgagtccccg gccggcacgg cggggaggcg acccaccggc
     9481 acctgggccg gtagcgtcac ccgagccggt gggcccagtt cgtcccgcca ccggtgtgcg
     9541 ctccaggccc ggtggtatgg gctgaacacc cgatagtggt cgccgccggt cgggcggagc
     9601 gcgcccgggt cgacgacggt gagcccgggg aagaaccgca ggtgcagccg gtgccgctcg
     9661 cattcggcgc ggagccgggt ggcccgtcgc tcggcgtacc gcgagacgtc ggcgctgagc
     9721 gcgatgccct ccgcacccac ctcaccggcc agccggatgg tctcggcgac cgggtcgccg
     9781 tgtcggagca ccaggtcgcc gccgaggcca cgcagtgcgg cccgcagcgc ggcgaggctc
     9841 tggtgcagga accgggtgcg gttgggcgac agctgcgcca gcgccgggtc caggacatag
     9901 agcggcacca cccggtcgaa ggcggcgcag ctggtggcca gcgccgggtg gtcgtgcacc
     9961 cgcaggtcgc gggtgaagag cacgatgccg gtacgcccgg tcacggcagc ggtgggccgg
    10021 gcaacgcgac gggcgtgccg gtcggggtga gcagggcccg gctggccacc gccatccggc
    10081 gtcgctgcgg caccgtggcc cgcctgacga acacgtcgta gtcctgggcc gccacctcgt
    10141 cgagaatccc gccatagagg gcgtacgcgg tgcggatgca ggcttgtgaa ccggcgtcga
    10201 gcagcgtcac tcccggtgcc gcggcggcgt agtgcgcctg ggcccggccc acctcgtgcc
    10261 ggatcagttc ccgtaccgcc tcggtggccc ggccggcggc ccggcaggcc gccaggtcgt
    10321 ccgctgtcac gccgaacgcg gccaggtcgt cgacgggcag gtacgtccgg ccccggtcca
    10381 ggtcttcggc gacgtcccgg atgaagttcg tgagctggaa cgcgaagccg agctggcggg
    10441 ccggctcgcg ggccgccgac gggtcggagc tgcccaggat gggcagcatc atggtgccga
    10501 tgaccgccgc ggacccctcc atgtagtcga ccagctggcc atagctgcgg tacgacgaca
    10561 cggtcaggtc catcgtcatg ctcttgagga acgtggcgaa gtcctcccgg tccaggtcga
    10621 agacggcgat ggtgtgcagc accgcgggca gcagcgggtc gtcgaccggt tcgccgtgca
    10681 gcccggcgac gaaccgccca ccccagtcgt cgagctgggc ggcgcgttcg gccggcggca
    10741 gggcctcggt ctgatcgacg atctcgtcgg cgtaccgagt gaatccatat aaagcgtgca
    10801 catgccgccg tttccaagcg ggcagcaggc gggtggcgag atagtaggta cggccatgac
    10861 gtttgtgcag ctcacgacat cttccgtagg cggcggcgag atcctgttcc atggcccctc
    10921 ccggtaaatc gacgcaccaa tcgacgcaac ttgcaacctt agggtacgct cagccccatg
    10981 gccaacgacg aactaacggg taacctgctt cgcgtggcgc ctgatcaatc gatcgacgaa
    11041 gatgatccga ttcaggccgt tctggccgct tacacccgag acctcggcac agccatcgac
    11101 cggatcctgg ccgagttcct gactcccgag gtcgattcgt tacgcgaaat cgacgcagct
    11161 atgggtgatt tcgccgccac ggcccgcgac tgcgttctgg ccggcggcaa acgggtccgc
    11221 tcgaccttcg cgtactgggg ctggcgtggg gtggtcggcg ccgaccagcc ggtcgatccg
    11281 gtgctgcccg cgctggccac gttggagctg ctgcacacct tcgcgctggt gcacgacgac
    11341 gtgatggacg cctccgccct ccggcggggc cggcccaccg cgcacgtcgc ggtggcctcc
    11401 cgacacgccg ccgccggccg caacggcaac tccgaccgct tcggcgaggc ggtcgcggtg
    11461 ctgatcggtg acctctgcat ggtctgggca gatcagctcc tggcccgcac cgcactgccc
    11521 gctccccaac tgatgcaggt ccggcgcggc tacgaccgga tgcgggtgga gacgatcgcc
    11581 ggtcagtacc tcgacgtcct cggcgagacc gatcccagca actggtcggt ggatcgggcc
    11641 ctgcgggtgg cccgctacaa gacggccagc tacaccgtcc agcggccgct gttgtttggt
    11701 gccagcctgt gcggagcgga cgacgccacg gtgatcaccg cctacacccg ctatggccgc
    11761 tcggtaggcg aggcgttcca gctccgcgac gacctgctcg gcgtctacgg cgacccgctc
    11821 accaccggca aaccggccgg cgacgacctc cgcaccggca agccgacagc cctgctcatg
    11881 ctggcccgcc aactggccag cccggcgcag cgccgggctc ttgcgggcac cggcccgcac
    11941 gtcaccgagt cggcggtcgc ccagctcgcc gaggtggtgc gcgacaccgg cgcggtcgac
    12001 cggatcgaac ggatgatcga cgagcggatc gaggacgcgc tggcgacgct ggacgctctc
    12061 accatcgacg agaccgcccg caccgccctg gtcggcctcg cgaccgcggc cgctcgacgg
    12121 tcggcatgat gggctccgta aacagaaagg tggtcgtcgg tgcgcaccgt tgacggacgt
    12181 acggaccggg tcgtggtcgt gggcgctggc ctgggcggcc tggcctgcgc gctgcacctg
    12241 gccggcagcg gacggcaggt gaccctgctg gaacgtgagc cggtgccggg tgggcgggcc
    12301 ggccggctca gcgtcgacgg ctacgagttc gacaccggcc cgaccgtgct caccatgccc
    12361 gacctgatcg ccgaggcgct cggcgccgtc ggcgaggaac tgaccgactg ggtcgacctg
    12421 atcccgctcg accccgccta ccgggcctac tacccggacg gctccacgct cgacgtgctc
    12481 accgacacca cccggatggc ggcggagatc tcccgggtct gcgggccgca ggaggccgac
    12541 ggctacctcc gtttcgtgga cttcgcccgc gagctgtggc ggctggagcg ggccgacttc
    12601 atcgagcgca acctcgacgc ccccaccgac ctgctcaccg ccaacctgct ccggctgctg
    12661 gccaacggtg ctttccggcg cctccagacc aagatcgacc agttcttccg ggacccacgt
    12721 acccggcgga tcttctcctt ccaggccatg tacgccggcc tcgccccgca cgacgcgttg
    12781 gcgatctacg cggtgatcgc gtatctcgac tcggtggccg gggtctactt cccgcgcggc
    12841 gggatccacg cggtctcccg gggcctggcc ggtgccgccg agaagcacgg cgtgcagatc
    12901 cggtacggca ccactgtcac ccaggtggtg accgcgaacg gccgggccac cggcgtgctg
    12961 accgccgacg gcgagttcgt cccggcggac gtcgtggtgc tcaaccccga cctgccggtg
    13021 gcctaccgtg acctgctccc accgtcgcgt ccgcgccggt tgacctactc gccgtcctgc
    13081 gtcgtgctac acgtcggctc gacccagggg taccgtcgca tcgcccacca caacatccac
    13141 ttcgggcggg cctggaaggg cacctttgac gaggtgatcc ggcgcggtga gctgatgacc
    13201 gacccgtccc tgctggtcac caacccgagc cggacagacc cggcggtggc gcccgccgac
    13261 cggcacacct actacgtgct cgccccggtc cccaacctgg accgggcgcc gttcgactgg
    13321 cgtggcgacc tcacccagcg ttacaccgac caactcatca acaccctgga gcagcgcggc
    13381 tacctcggct tcggcgcggg cgtcgaggtg ctccgggcgg tcaccccggc cgagtgggcg
    13441 gagcagggca tggccgccgg caccccgttc gcctcggcgc acacgctctt ccagaccggt
    13501 ccgttccggc cgtccaacat gcatcgatca ttgtccaacg tggtcttcgt cggctcgggc
    13561 acccagcccg gcgtgggagt cccgatggtg ctcatctccg gcaagctcgc cgccagccgg
    13621 gtgaccgggg aaggcaagtg aacaccggca gtcccaccca gcgcagcatc gacgtcgcga
    13681 acggaggacg gcactgatgc caccgtcccg ggaggctcac ctggtcgagt tggtcgacga
    13741 cgctggtcac gccgtcggcg agaccacggt ggccgccgcg caccggccgc cgggtcagct
    13801 gcaccgcgcc ttctccgtgc tgcttgtcgc gccggacggc cggatgctgc ttcaacgccg
    13861 cgcggcggcg aagacccggt ttccgctgcg ctgggccaac tcctgctgcg ggcacccctg
    13921 ccgggtgagt cgctcaccga ggccgcgcat cggcggctcg cggaggagtt gggggccggc
    13981 ccggtgccac tgaccgaggt cggggcctac gtctaccgcg ccgaggatcc agccaccggg
    14041 cgtgtcgagg tggagtacga ccacgtgctg cgcggcgaac tcagcccgga caccgtgttg
    14101 cgccccgacc cgacggaggt cgccgagctg cgttgggtcg acccggccac acttgccacc
    14161 acactcacca cagatcccga ttcgtacgcc ccctggctgg gcggcgtact ggaccggctg
    14221 ctgcacccgt cggagcggtc gggtggccga tgaggcgctg agcgccggcg cggtcgcccg
    14281 tcgactgggt gtggcagtga ccacgctacg tacctggcat cagcggtacg gcctcgggcc
    14341 cagtcagcac gtgcccgggc accaccggcg ctacacccct gccgacctgg cccggctgga
    14401 gatcatgctg cggctgacct ccgagggcgt cagcccggcg gaggcggccc gctgggcgcg
    14461 gcaggtaccc ggcacaccgc ccgacggcac cgccgtccgg gcgcggccga ggagctttcg
    14521 agacggcggt ggcacggcga tcccggtcgg tcgcgccggc ccggcggccc gcggtctggc
    14581 ccgcgccgcg atgcgactgg acgccctcgc gatcactgag acggttaccc gggccattgc
    14641 caccgacggg gtcgtccgca cctgggaccg gctgctccgt ccggtgctcg tcggcatcgg
    14701 tgaacggcac gccgcgaccg gttccctgat cgaggtcgag cacctgctgt cccggtgcgt
    14761 gtcggcggcg ttcgccgcca tcgtgacggc tcgcccggct cccgccgggc cgcctcgcat
    14821 cctgctctcc tgtgccgacg aggaacagca cagcctgccc ctggaggcgc tggccgccgc
    14881 cctcgcggag gccggtgtca accaccggat gctcggtgcc cgggtgccgg tgaccgccct
    14941 gctggacgcc atcgaccgga ccgggccggc cgccgtggtg gtctggtcac atctccggtt
    15001 caccgctgac gcgtcccagc tcaccgccct gctcaccgcg ccacgccgcc cactgctggt
    15061 gctggccgcc gggccgggtt ggcaggccga caacctgccc gccggagtgg tccgcccggt
    15121 cgacctggcc gaggcgctct cgctcgctgt cgccgtacgc gactcgctgg accgctcggc
    15181 cgcctcctga tccgtcccgg cgcacgaact ggcccaccac cggcccccgc gccaaggtgc
    15241 cgcggtacgc agggcgttcg ggccctgacc cgccgtggat gccggtgaaa ccgggcaact
    15301 agcgtcgagg ggtacgccta ccccgaccct cgggagcgaa cgatgcgttc acgtctcctg
    15361 ctcgcctgcg ccaccggcct ggccgtgctg ctggtgtccg gctgcgccgg cacgggcccg
    15421 cccgacacca gccctccggc gagcccgccc ccctcggccg cactgccacc gcaggcgacg
    15481 ccggccccga cccgcaccac accgcccaaa ccgcgcctac gggcgctgcc ggccaagctg
    15541 ccggcgggtc tggtccggac caccggaaac gccaaggtcg ctctcacctt cgacgacggg
    15601 ccggacccgg cctggacccc gaaggtgctg gaccggctga agaaggccaa ggtcaccgcc
    15661 accttctgcg tggtggggac ccaggtccgc aagcaccctg aactggtccg tcggatcgtc
    15721 cgggagggcc atcagctctg caaccacagc tggaaccacg acctcgacct ggcccgtcga
    15781 ccgatcgccg agatccgtgc cgacctggtc cggacgaaca aggagatccg gcgggcagtg
    15841 ccggacgcgg aggtgccgtt ctaccgccag cccggcggcc ggtggaccgc cgaggtggtg
    15901 aaggtggccc ggaagctcga catgcggtcg ctgcactgga cggtcgaccc acaggactgg
    15961 gccaagccga ccgccgcgac catcgcgaaa cgggtcaagc gcaccgccaa gcccggagcg
    16021 gtcgtcctgc tgcacgacgg cggcggtgac cgggccgcca ccctcgccgc ctgttcccgg
    16081 gtgatcactg cgctgaaacg cgaccatggc atcgtgcgtc tccgctgact cccgcctgac
    16141 ctgctctttc tcggcccgtt gccgctgcgg ccataccggt ttggtcgtcc ggtgagacat
    16201 cacgtatgct ttcgaagcct ccggcggggc cggatgggag caagtccgca caacgttgcg
    16261 agtgtgcaat gatggcgggg ccgccctcat cgtctagcgg cccaggacgc cgccctttca
    16321 aggcggtagc acgggttcga atcccgttgg gggcacggtc cggcttcggc cggatgcaac
    16381 acgagctggg tcctgtggag cagttggagt gctcgccgcc ctgtcaaggc ggaggtcgcg
    16441 ggttcaagtc ccgtcaggac cgcaagcgct gacgccgcgc catgcgcggc gttccgcgta
    16501 tcggggaatg cgaccctcgc ggcggtggtc ccgccctccg ggtagcatga gccgagcacc
    16561 acggccaggt agctcagttg gtacgagcgt ccgactgaaa atcggaaggt cggcggttcg
    16621 accccgcccc tggccacata gcctttcgcc gggctttaca aagcgctgac cagcgtatcg
    16681 ccggtcagcg cttttgtttg ccccatcggg tagtactggc gtgagctgcg catgcgggca
    16741 tgagccggta tggtccgggc ctatgggaca cgggatggcc gatgcgacgg aagtcacgca
    16801 ggatcatgac cggttcgccc ttcgcagcac cctgctggtt cccacccccg ccgagcgggc
    16861 ctatgaggtg ttcaccggga acatcgccga ctggtgggtg acggaataca cctggtccgg
    16921 gccgggtgcg ctcgccgagc tgggcatgga gccccgagcc ggcgggatgc tctacgagat
    16981 cggtccctac gggttccgca acgactgggg tcgcgtcgtc atctgggatc cgcctcgccg
    17041 cctggtcttc acctggcaga tcggggcgga ccgcgtcccg gtgccggacc cggcgcgggc
    17101 cagcgaggtc gaggtgctct tcacctcggc aggttccggc accctggtcg aggtcacgca
    17161 ccggcacttc gacaggcacg gcgaggctgc cgaaggctac cgggaggcgt tgaccgccgg
    17221 ctggcacgag ctgctgtccc gcttcgccgc cacggtgacc gaccgcctga catgaggccg
    17281 ttccgggccg ataggggcca catccgcggg gatgctgatc agctggcccg gtgccgcagc
    17341 gtggccactg ccgaaccagc gagggtgagc aggcattcgg gcagcagccc gtcggccgcc
    17401 gccgcaccga acagcgcctc agcggtgtcg aggtcggcgt tggcgtacgc gctgacgaag
    17461 cgggccaccc agcgggcgtc gtactccgcc tgctcgatgc cgggaaaatc gagcgcacag
    17521 gttcccgacg gcaccggatc gccgaccatc gtcgcggcca ggcaccatgc cacaccgtac
    17581 gcgccggcga ggccgtcccg atcgaccacc gcgtcgaagg tccccgtcac cgcctcggag
    17641 tccccgtcga gcgccgaacg gagaatggca ttggcgtcgt cgagcatttg ctgtggcgag
    17701 tcggtcaccc accgcacagt agggctgccg gtcaagaagc gacagatgac tactctccgt
    17761 gcatatcaga ggcgacctgc ggatagccgg acctccatgg tcccgttgac cggcgcggca
    17821 cgctagtctg cgcagcggac cttcgccgga ggaaggacga caatgcacat gtcacgcggc
    17881 tcgcggacgg ccgctctggc tgcctgcgca gcgctcctgc ttgccaccag cgcctgcggg
    17941 gacgaccagg ccgaggaggc gaccacccaa caggtgcgcc tctacggcac cgacggcaac
    18001 atgtccaatt cgtacgcgga cgagttggag gatcgtgcca gtctggtgga cggcatgaag
    18061 ggcaccacgc ccctcacacc gctgcccgag gacttcaaga agcggctact gtctgtcgat
    18121 ccgcagcttg acggcttcct ctacgccgcc gaggcgtacg acgcggtggt gatcagcacc
    18181 ctcgcggcgg agatcgccgg caccaccgat ccggcggcca tcgcgaagca gatcgtcggc
    18241 gtcaccaacg acggcaccag ttgtggcagc ccggcccagt gtctgcggct catccgcgac
    18301 ggcagggaca tcgagtaccg cagtgtctcg atcacccgcg ccggtttcac cgacgccggt
    18361 gagccggcca ccgccagcta cgcgacgctg cacttcgacg gtgagcggct caacgacgcc
    18421 aagacggagt tcgtcggcgc cggcgacgag tcggcggcga gcagcaaggc gccgccgagg
    18481 gtgaaccgtc cggccggtgc cggcaacggc ccgctggtca tcggcggact gctgcccaag
    18541 acgggtgacc tggcgctggc ctacccgccg ctggccgccg gtaccgcgct ggcgatcaag
    18601 gagatcaacg acgccggtgg ggtgctcggc gaggacgtgg tctgggtcga cggtgatgac
    18661 ggcaccaacc ccactgtcgc caaggccacg gtggcccgcc acatcgatgc cggcgttcac
    18721 gtgatcatcg gcgcgggtgg ctcgggcatc tccgccgccg tgctggagga cgtggtccag
    18781 ggcggacgga tcctgttctc cccgtcgaac accgcagcca gcctgaccaa cgcggacgac
    18841 aacggcctct acttccgtac cgcccgccgg acagtctcca gggccgggcg ctggccgacg
    18901 tcatcctccg ggacggtccg cagaagatcg cgatcgtggc ccgtaaggat tcctacggcg
    18961 agggcctcca ggacgtcgtc cgctccgagt tggagcgggc cggtttcggc ggcgacaagg
    19021 tgaagttgct cagctacgag cccggtgagg gtgccgaggc cccaccgatc aacttcagcg
    19081 acggcgccaa gcagatcaag gagttcggcg cggacgccgt cctgatcatc ggcttcggtg
    19141 agtccgccgc cgtggtccgg gcgctcgcgg acgctgacgt accgctggcg gcgctgaacc
    19201 gctgaccatc gcccgacggc cgcaccggac acggtgcggc cgtcgtggtg ttgccgggcc
    19261 cggtcagcgc ccgcgccgcc gctccagaaa ctcggtcatc cggtggtgct tctcctcgtc
    19321 ctcgaagagc accgcctgac tcaccaggtc cagctgcggg tgtgcggcgg ctggcgcgtc
    19381 cacggcgagt ttggtcagcc gcagcgccaa cgccgatccc ttggccatct cgtcaatgaa
    19441 ctcgtgtgcc gccggcagca gcgcctccgg tgccgccacc acctggttca ccaggccgat
    19501 tcgtagcgcc tccgcggcat ccacccgccg cccggtgaac agcagttcct tggcgcgggc
    19561 ctcaccgacc agcgccggca gccggtgggt cgcaccggca ccagccagga tgcccagtcg
    19621 cacctcgggc tgcccgaaga ccgcgcgctc cgtgcacacc cgcagatcac aggcgtacgc
    19681 caactcggcg ccgccgccca gcgccggccc gtcgacggcc gccacggtcg gcatcggcaa
    19741 cgcccggatc cgggcgaagg cggccatgtt gatcgcggcg agcgcgtcca accggccccg
    19801 ctcacgcaac tggccgatgt cggcgccccc ggcgaagatc ccgtcggtcc ccccggtcaa
    19861 caacagcatc cggggcgggc ctccaactcg gcgcagacgt cgtgcaacgc ggcgatcagg
    19921 tcggcgtcga tggcgttgcg cttctccggc cggtccaggg tcaccaccag ccggtccgcg
    19981 cgctcctcga ttcgcagccc ggtgctcatc gcaccgcccc cggctcgggc gactcgatgc
    20041 cgcccgcgcg gaccccgtcg gcccaactgt agaaaccctg tccggacttc ttgcccagcc
    20101 ggcccgcggc caccatctcg acaagcagcg acggcggcgc gaaccggtcc ccgtacgcgg
    20161 cctggagggt acgggcgatg tcgaggcgga cgtccaggcc gaccaggtcg gtcagttcca
    20221 acggcccgac cgggtgccgg tagccgagcg ccatcgcctt gtcgatgtcg gcggggctgg
    20281 ccaccccgtc ggccaccatc cggatcgcct ccagcccgag ggccaccccg agtcgcgagg
    20341 tggcgaaacc gggcatgtcg cgtaccacga cggggtcctt gcccagccgg gcggcgagcg
    20401 tgcgggccgc gtcggtggtc tccgctgcgg tggccggccc aaccacgatc tccagcagcg
    20461 tcatggccca gaccgggttg aagaagtgca gcccgcagaa gcgttccggt cgtgtcaaac
    20521 cgtcggcgag ctcggtgatg gggatgcttg aggtgttgct gccgagcagc agcggccgca
    20581 gcgcctccgc ctcgatcagc accgcccgct tcaggtcgag tcgttccggc accgcctcca
    20641 cgatcacgtc cggctccgcc gccacctcgg cgagacccgc ccgcagggtg acccgctgcc
    20701 ggcttgcggt ggcctgctcg gcggtcgcct tgccgcgccg cacggcgccc tcccacaact
    20761 gcgcgagccg ggccacggcc gcgtcgccac gggcgcggtc cacctcgacc agttccacca
    20821 gatgtccggc ctccgccgcc acgtacgcga tcccgaggcc catggtgccg gccccgacca
    20881 cgacgaaccg ctcagtcatg gtgacaccac cgcacagtga cgttttcccg ctcgctgacg
    20941 ccgctggcgt gcgggatcgc cgccacgccg gagccagccc gtacgctccg ctcagtcata
    21001 cgtgcgacct tatgcagcac cggccacggc ccatgcgtgg gggcgggcga ggtcgggtaa
    21061 atgatcgccg acaaccaagg gaaggacgag cagatgagcc aggcaccgga gaccgcgggc
    21121 cacgcgggta ccgaggagac cgtcgagact cgcggcgacg agcgcatcga cctgctgcgt
    21181 gccgacacca acaacgacgg ccgtaccgac gtctgggtgg tcgacaccga cggcgacggc
    21241 aaggccgacc tgttccagtt cgacaccgac ggcgacggca aggtggacgt cacgatggtc
    21301 gacctcgacg aggacggcca gcccgacgag atcgtcgacg gcgacggcgg cctcccgccc
    21361 gagcagcttc ccccgaccgt ccaggtctga ggtgtaagga ggggcccctg ttaacgcctc
    21421 cggtagagca gggggcccct attaacaaat gccagacgcc agacggccgc gggacgccag
    21481 gcacgtcggc gcgggggcgg gcggcacgtc aggcggacag gcggagcgtg gcgaggtagt
    21541 agggcgcgtc ccggtcgtcc acgtcaacca gtcgccaggc ggtgccgtgc accaggccgg
    21601 ccagttcctc gggcgagcag accaggtagt cgaaccaggg cgtacccagt tcgcggtaac
    21661 gcaggcgcag ccgcagctgc ccaccgagcc ggccgcgtcg acggttgtac tcgtgatagc
    21721 cggtgtgtac gggatcgcgg gtgccgtacg gatcggtgcc gtgcgcgatc acctgcgccc
    21781 cggggcgggc catcgcggcg agggcggcca ggaaggcggg agcgcgttcc cggccctcga
    21841 tcagccccag gttgttgccg agcagcagga aggtgtcata gcgccgtccg ctcgccgcgt
    21901 gctcgtcgac agtgccgtgc acgaggtcgc gtacgccccg gcggcggcac accgcgagcg
    21961 caccgggtga gacgtccagc ccggtgaccg gcacctcgcg ctcctgaagc agcagtgcga
    22021 tccggccggc gccgacgccg atgtccaggg tgtcgccgcg tacccggtcc accgctcggt
    22081 ggtcgtgcgg ctgccagtcc gctggcccgt ccaggtagtg cgctgccgg
//
