LOCUS       NZ_AP023354            23306 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Actinocatenispora sera strain NBRC 101916 chromosome.
ACCESSION   NZ_AP023354
VERSION     NZ_AP023354.1
KEYWORDS    RefSeq.
SOURCE      Actinocatenispora sera
  ORGANISM  Actinocatenispora sera
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinocatenispora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Actinocatenispora sera NBRC 101916
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7044238)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 251x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018324685.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 04:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,585
            CDSs (total)                      :: 6,501
            Genes (coding)                    :: 6,404
            CDSs (with protein)               :: 6,404
            Genes (RNA)                       :: 84
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 26 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 1 of 97
            Pseudo Genes (multiple problems)  :: 10 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:48:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6879759
            Orig. end                         :: 6903065
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..23306
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="18"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23306
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23306
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13306](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13306)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            811..1209
                     /locus_tag="Asera_RS32320"
                     /old_locus_tag="Asera_64990"
     CDS             811..1209
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020515187.1"
                     /locus_tag="Asera_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_64990"
                     /product="RidA family protein"
                     /protein_id="WP_030449416.1"
                     /transl_table=11
                     /translation="MINRSNPPSLHAPDGYHHVTIAEAGRTAYLAGQCPVDADDQLVGP
                     GDVLTQVDQVVANCLLALRAAGAEPDQVVRSVVYVASDEQPVLVSVWERLQASPLAPAF
                     TTASTLLGVTALGYAGQLVEIDLTAALS"
     gene            1206..1736
                     /locus_tag="Asera_RS32325"
                     /old_locus_tag="Asera_65000"
     CDS             1206..1736
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65000"
                     /product="hypothetical protein"
                     /protein_id="WP_030449417.1"
                     /transl_table=11
                     /translation="MTAADGTEALLIGGRSGVGKSSVGWEIAALLKAADVAHTYVEGDT
                     LDQTWPKPPGDATLATLTEENLRALWRNFAARGQRRLIYTNTSAVLDADLIRRATGAAR
                     CIGVLLTASDTTTLGRLAAREIGSELDLHTHRSAQMADRLDRDAPSWVHRVPTDGRTVT
                     DIATEIIGITTWS"
     gene            complement(2392..3390)
                     /gene="hpnH"
                     /locus_tag="Asera_RS32330"
                     /old_locus_tag="Asera_65010"
     CDS             complement(2392..3390)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076658.1"
                     /locus_tag="Asera_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65010"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_030445142.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-18, bitscore: 66.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 7e-08, bitscore: 30.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIPFRQAAKIGAYLFRQKLAGRKKFPITLELEPLFACNLACEGC
                     GKIQHPHDVLKQRMPVERALAAADECGAPVVCLAGGEPLMHPQVEDIVEGLIQRKKFIY
                     LCTNALLIPRKIDKLHPSPYLSFAVHIDGLEERHDESVAKKGVFTQAVDAIKMAQDRGF
                     RVTTNTTFFNTDTPQTVIEVLDYLNNDLKVDGMMLSPAYAYEKAPDQDHFLGVEETREL
                     FRKAFANGRREKWRINHSPAFLDFLEGKRDFACTAWGIPSYSLFGWQRPCYLMGDSYAK
                     SYRELVEDTDWEKYGRGRDPRCANCMAHCGYEPTAIMATMSSLRESIRAVR"
     CDS             complement(3476..3679)
                     /gene="allorf_6883235_6883438"
                     /locus_tag="allorf_6883235_6883438"
                     /protein_id="allorf_6883235_6883438"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSPCPPMSGLPGTTVFPAHRAVDRAGRRRLRRYLPGFALCTVCGS
                     TVRWCRHRASTAQHRFAVVVQI"
     CDS_motif       complement(3545..3679)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSPCPPMSGLPGTTVFPAHRAVDRAGRRRLRRYLPGFALCTVCGS"
                     /locus_tag="allorf_6883235_6883438_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3476..3544)
                     /prepeptide="core"
                     /locus_tag="allorf_6883235_6883438_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2568.0"
                     /monoisotopic_mass="2566.4"
                     /core_sequence="TVRWCRHRASTAQHRFAVVVQI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSPCPPMSGLPGTTVFPAHRAVDRAGRRRLRRYLPGFALCT
                     VCGS"
                     /leader_location="[3544:3679](-)"
                     /alternative_weights="2586.0"
                     /alternative_weights="2604.0"
     CDS             complement(3487..3621)
                     /gene="allorf_6883246_6883380"
                     /locus_tag="allorf_6883246_6883380"
                     /protein_id="allorf_6883246_6883380"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPWTGRAGGGFGGTCPDSRSARSVDPPFGGAGIALPLRSTGSLW"
     CDS_motif       complement(3583..3621)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPWTGRAGGGFGG"
                     /locus_tag="allorf_6883246_6883380_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3487..3582)
                     /prepeptide="core"
                     /locus_tag="allorf_6883246_6883380_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="3046.4"
                     /monoisotopic_mass="3044.6"
                     /core_sequence="TCPDSRSARSVDPPFGGAGIALPLRSTGSLW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPWTGRAGGGFGG"
                     /leader_location="[3582:3621](-)"
                     /alternative_weights="3064.4"
                     /alternative_weights="3082.4"
                     /alternative_weights="3100.4"
                     /alternative_weights="3118.5"
                     /alternative_weights="3136.5"
                     /alternative_weights="3154.5"
     gene            3673..4908
                     /locus_tag="Asera_RS32335"
                     /old_locus_tag="Asera_65020"
     CDS             3673..4908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441096.1"
                     /locus_tag="Asera_RS32335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65020"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_084131024.1"
                     /transl_table=11
                     /translation="MTRLRTAIATLAVLTAAVATTAGCTGDGADTRDTIAGPTPAADRT
                     ALSLSVRPKAHATGLPVSTEIGATVTGGSVEEVRLVDAHGNHVDGSLRPDGTSWVPDRP
                     LAYHRRYTATVVAVGARRQHVERRTTFTTMSEPSNRVGTGMYVQDGQTYGVGMPIAVEI
                     LRDVPKNLRASVQRRLFVHSDPPQPGAWHWFGPRRVEYRPATWWQPGTKLTVRMALGGL
                     PMGHGGYGDTDRSATARISSDRIELRITNRPKQMKVYRNGRLARTMPVSLGKADAPSSS
                     GHMVIMDKAAHTVFDTRGIPGENYVAPVDNAQRLTWGGEFIHAAPWSVADQGHRNVSHG
                     CVNISDPDAAWLFARTHIGDPVTVSGTGTRLAPGNGWTDWDMDWDTFVAGSALPVPDSV
                     RNATAYDPYPRR"
     gene            4987..5889
                     /locus_tag="Asera_RS32340"
                     /old_locus_tag="Asera_65030"
     CDS             4987..5889
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (14-218). E-value: 3.8e-33.
                     Score: 106.9. Matches aSDomain:
                     nrpspksdomains_Asera_RS32340_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661898.1"
                     /locus_tag="Asera_RS32340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65030"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_030445140.1"
                     /sec_met_domain="ADH_N (E-value: 4.2e-10, bitscore: 38.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVFDRHGGPTVLQLTEVAVPEPGRGQVRIRVRAAGVNPIDGK
                     LRAGGGWPIELPSTPGVEGAGVVDAVGPDTDGFAVGDEVLGHTATGSYAQFALSDRVVP
                     KPAGLSWDVAAAVPVAAETALRVLRLLDLSPGETLLVHGASGSVGSLAGQLARRRGVTV
                     VGTAGAAGRDRLGRLGVTAIAYGDGLVDRVRSVAPHGVDAVFDAAGRGALPDSIALRGG
                     PERIVTIADPNAAEYGVLFTGGSEVMVEPAAIAEVAKQVAAGDLTVPIAARYQLADAAE
                     AQRLSDTGHAGGKIVLTVD"
     aSDomain        5029..5640
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Asera_RS32340_PKS_ER.1"
                     /evalue="3.80E-33"
                     /label="Asera_RS32340_PKS_ER.1"
                     /locus_tag="Asera_RS32340"
                     /protein_end="218"
                     /protein_start="14"
                     /score="106.9"
                     /tool="antismash"
                     /translation="LQLTEVAVPEPGRGQVRIRVRAAGVNPIDGKLRAGGGWPIELPST
                     PGVEGAGVVDAVGPDTDGFAVGDEVLGHTATGSYAQFALSDRVVPKPAGLSWDVAAAVP
                     VAAETALRVLRLLDLSPGETLLVHGASGSVGSLAGQLARRRGVTVVGTAGAAGRDRLGR
                     LGVTAIAYGDGLVDRVRSVAPHGVDAVFDAAGRGALPDSIA"
     CDS_motif       5167..5202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Asera_RS32340_0001"
                     /evalue="1.00E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="Asera_RS32340"
                     /protein_end="72"
                     /protein_start="60"
                     /score="9.0"
                     /tool="antismash"
                     /translation="GVEGAGVVDAVG"
     CDS_motif       5227..5280
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Asera_RS32340_0002"
                     /evalue="3.50E-01"
                     /label="PKSI-ER_m5"
                     /locus_tag="Asera_RS32340"
                     /protein_end="98"
                     /protein_start="80"
                     /score="3.9"
                     /tool="antismash"
                     /translation="GDEVLGHTATGSYAQFAL"
     CDS_motif       5392..5454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Asera_RS32340_0003"
                     /evalue="1.40E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="Asera_RS32340"
                     /protein_end="156"
                     /protein_start="135"
                     /score="14.5"
                     /tool="antismash"
                     /translation="GETLLVHGASGSVGSLAGQLA"
     misc_feature    5932..5947
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     misc_feature    5971..5991
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            6014..7015
                     /locus_tag="Asera_RS32345"
                     /old_locus_tag="Asera_65040"
     CDS             6014..7015
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="Asera_RS32345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65040"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_035295631.1"
                     /transl_table=11
                     /translation="MDGTHLDLRFADVLRSYRTTARLSQRELADRAGLSVGAVRDLEQG
                     RRRTPRRSTVRRLGAALGLPAPSAAGPDPARRFVLRVLGPLELRVGGRAVRLGPPRQRA
                     VLGLLALCPNALVHREEIIDRLWARAAPATAVHLVQAYVSRLRALLLPDAPPERRRAVL
                     ESTGASYRLRVRPDGLDLLRFGRLTEQARTAVAAGNHLLAGERYEAALRLWRGTPLADV
                     DLLRGSAPVATLAEQRVATAIRYAEAAARTGRHHPVPQLRLLADADPLHEALHARLMLA
                     LAAGGQQAAALRVYAEISARLADQLGLTPGPELTDARLQVLRGGADPRPGPG"
     gene            complement(7043..7615)
                     /locus_tag="Asera_RS32350"
                     /old_locus_tag="Asera_65050"
     CDS             complement(7043..7615)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="Asera_RS32350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65050"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030445139.1"
                     /transl_table=11
                     /translation="MPKINAATVAEHRAQQRAALVRAAIDILIEQGAGAVTPGAVGARA
                     GLARSSFYQYFPSGAAILAAIVEDAFAAADTARDQALRTVEHPAGHIDAFVRAELRLAA
                     QGLHRPAAALMRAELPQECRDRVHELHRLHYLPLQEAIAELSPTAPQLTAQLVGGLLQS
                     AMAAVEGGADPDHVAERTLRLIHHGLG"
     gene            complement(7643..8362)
                     /locus_tag="Asera_RS32355"
                     /old_locus_tag="Asera_65060"
     CDS             complement(7643..8362)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442966.1"
                     /locus_tag="Asera_RS32355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65060"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_051801933.1"
                     /transl_table=11
                     /translation="MTPTTPATATTVDGTTLPAALRLAGVTLRLGSGAQQVTALDRVDL
                     TVARGEFLALTGPSGSGKSSLLAVAGGLQSPSEGTVHVAGTDLTTLTEGQRTAHRRNHI
                     GYVFQHANLLASLTAREQLLVAAHIAGRLDGSARQRADELLDAVGMTARADRRPHQLSG
                     GERQRVGLARALLLAPEILLVDEPTSALDRARSRDIVDLIARQTRAQNTATVMVTHDTE
                     ILDAADRVRNLRDGRLT"
     gene            complement(8359..9477)
                     /locus_tag="Asera_RS32360"
                     /old_locus_tag="Asera_65070"
     CDS             complement(8359..9477)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286883.1"
                     /locus_tag="Asera_RS32360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65070"
                     /product="ABC transporter permease"
                     /protein_id="WP_030445137.1"
                     /transl_table=11
                     /translation="MFLALRDLRFARGRFALIGAVVALIAMLGVILSGLASGLADSGVS
                     ALRALPVTHLAFDKSATGELFSRSTVTKTTWEAWASQPGVRRAEPFGQQLVHARLAGSA
                     GKQLDLAVFGVEPDGFLAPPPVSGRPLSAAPNGVLISADIAAEGVRIGDRLTAGQAGTE
                     LTVVGTIGHASFGHIGVVYAPLPLWQQLHYGLAGPLPAAATDQATAVALQLAPGVDPAT
                     ADRRLGTRSVDKAGTYAASPGYTAESSTMTLIRAFLYAISALVVGSFFTVWTIQRRQEI
                     ALLKAIGAGTGYLLRDALTQVTVVLLLATAAGTGVGLALGRAMNRSAPFSLDPGQVTMA
                     AALLIVLGLAGAAVAIRRITKVQALTALGANR"
     gene            complement(9477..9857)
                     /locus_tag="Asera_RS32365"
                     /old_locus_tag="Asera_65080"
     CDS             complement(9477..9857)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015925.4"
                     /locus_tag="Asera_RS32365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65080"
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_211255501.1"
                     /transl_table=11
                     /translation="MSRHLRAGSGALRSEEMGAQSMYTVMNRIPVPGGEESTFEERFTA
                     SMGETLPGVDGLLGARLLRPAQAGGVYVAVMEFTTRDAFTAWMRSPSFRAAHGPSTQGM
                     AGTVEPFETVAAVADGVPGESA"
     CDS             complement(9869..10000)
                     /gene="allorf_6889628_6889759"
                     /locus_tag="allorf_6889628_6889759"
                     /protein_id="allorf_6889628_6889759"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNGRPGRWAAPGGALVPPGVEFLAARGEAPTAKLADTCVGNMR"
     CDS_motif       complement(9962..10000)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNGRPGRWAAPGG"
                     /locus_tag="allorf_6889628_6889759_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9869..9961)
                     /prepeptide="core"
                     /locus_tag="allorf_6889628_6889759_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="3019.5"
                     /monoisotopic_mass="3017.6"
                     /core_sequence="ALVPPGVEFLAARGEAPTAKLADTCVGNMR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNGRPGRWAAPGG"
                     /leader_location="[9961:10000](-)"
                     /alternative_weights="3037.5"
     gene            complement(10001..13306)
                     /locus_tag="Asera_RS32370"
                     /old_locus_tag="Asera_65090"
     CDS             complement(10001..13306)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="Asera_RS32370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65090"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_030445135.1"
                     /sec_met_domain="DUF4135 (E-value: 1.8e-96, bitscore:
                     322.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-51, bitscore:
                     174.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAALVALRRAMSQALSAVERGKPAVVDPGRSARADRIMARWRAQ
                     PPFHKAGWFDRRLAADGLTVEVVHDQLAEPPDALADRVGLGHAGATAEVAGGSWVDELV
                     AAFATPAPIELPAEHDLAAVAGPLLTAAAGRLRTALAPLGDTPFGDPDAAVARFLPSLT
                     AHAYALTQRSMVLEVQVAKVTGALTADTPTGRYRQFLDRLRDPGIAAGLLAEYPVLARR
                     LVTVCRNWVTASAELVHRLVADLPELSARFAGGAPLGAVTQLETDLGDRHRGGRTVARL
                     RFEHGVRILYKPRSLAVDAHYQQLVAWLNGYLRWPLAELPCLARDGYGWVAHVQQRYCS
                     DGADLHRFYHRAGTLTALLYLLEATDCHAQNLIAVGDQPVLIDHETLLTPRLREDLHEL
                     SAAELVANTAIGGSVLRSGMLPYRAWVEVGNGGADVSALGWDPRELPPREIPELRDAGT
                     DEVRVGYRRVGIGQVASRPLPPGEPLRLADFRADLDAGFTEAYRILAGHREAVRELLDA
                     FADDEIRVLCRETMEYRTLVVAGLHPDRLRDGLAADRHLDRLWELVPRLEAVAPLLASE
                     RADLAATDVPVFTARPGGTALCDAAGRKLPAVSDEPALSLALAKLDALGEDDLAAQRSL
                     LRWAVESSRTDHVPQADGTVAAVVPAAPLPAADRVAARALEYAGRAADRLVALAYRRDG
                     SLAWAGPGLLPGGAWALAPLGADLYSGTAGVTLFLARLAEVTGDAAHRAAAAGALDTLR
                     AQVLRLPRNLAGGLCGYGGVLYALAHLHAIRPDEELAALADNMAAGVGELATDDAEYDV
                     ISGAAGSIAGLAAWHAVRPSAAVRTAVAACADQLCARAERQPAGVGWRAASMADVSPRP
                     LAGFAHGAAGPAWALARAATVTGDRRYLPTAAAALAYERSLFDAAAGNWPDVRTGIPHE
                     ASFPVLWCHGAVGLGLSRTGLLAAARELGVADLGSDQSAGGGVGGAGTVAELTADLRTA
                     LDTAAAAGFGWNFSLCHGDLGALDLFCTAPAVLDEAAAAAAGETALRQTAAILDRLDER
                     GWVCGLAGGGENPALLVGLAGIGYGLLRAAAPDRVPSVLALHPPVAGRNGSSG"
     gene            complement(13487..13666)
                     /locus_tag="Asera_RS32375"
                     /old_locus_tag="Asera_65100"
     CDS             complement(13487..13666)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="Asera_RS32375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65100"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_030445134.1"
                     /transl_table=11
                     /translation="MSAEELVRAWRDEDFRLELESAVAHPAGEVDRELYVSTGAASTCN
                     YASVTCAHICSCAA"
     CDS_motif       complement(13547..13666)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSAEELVRAWRDEDFRLELESAVAHPAGEVDRELYVSTGA"
                     /locus_tag="Asera_RS32375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13487..13546)
                     /prepeptide="core"
                     /locus_tag="Asera_RS32375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="1786.0"
                     /monoisotopic_mass="1784.7"
                     /core_sequence="ASTCNYASVTCAHICSCAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSAEELVRAWRDEDFRLELESAVAHPAGEVDRELYVSTGA"
                     /leader_location="[13546:13666](-)"
                     /alternative_weights="1804.0"
     misc_feature    complement(13644..13658)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(13848..14801)
                     /locus_tag="Asera_RS32380"
                     /old_locus_tag="Asera_65110"
     CDS             complement(13848..14801)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020512495.1"
                     /locus_tag="Asera_RS32380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65110"
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="WP_030445133.1"
                     /transl_table=11
                     /translation="MTAGEQPPDPAMVWVPGGTFTMGSDLADYPEEGPPHRVTVDGFWI
                     DPTPVTVVQFARFVTDTGYVTVAERPLDPAQYPNVDRRLLLAGSLVFTPTDKPVDLTDM
                     QQWWRYVPGASWRHPEGPRSDVTGRDDHPVVHVCAEDVEAYAQWAGKQLPTEAEWEFAA
                     RGGLDGAPYAWGEEFLPGGKRMANTWVGEFPWHNLKPARRQRTTPVRSFPPNGYGLYDV
                     AGNVWEWTADFYRSNHPATHACCAPPVNPRVDDAEGSYGDQEQGGAHVPRRVLKGGSHL
                     CAENYCRRYRPAARQAQQVESAMSHIGFRCLARPST"
     gene            complement(14815..15993)
                     /locus_tag="Asera_RS32385"
                     /old_locus_tag="Asera_65120"
     CDS             complement(14815..15993)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020518451.1"
                     /locus_tag="Asera_RS32385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65120"
                     /product="metallophosphoesterase"
                     /protein_id="WP_035295626.1"
                     /sec_met_domain="Metallophos_2 (E-value: 3.9e-08, bitscore:
                     32.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATEDVRAEPGRRIGRVVAFAAVLVAVEVLLFGLSWWTLVLAPG
                     WPTGVVVVGTVLFVAAAIGFPVLMNLGHRRANDPAARTSDVLLGVIGVLFVWCTLAQLV
                     RLPLLATDLSGTAVSRVVAAVGLVITIVLLAWGYVEAMRLPRVAEVSVRLDRLGAGLDG
                     LRVVLITDTHYGPIDRADWSRRVIDVVNELDGDIVCHTGDIADGSVNARLAQAAPLGDV
                     RATLARAYVTGNHEYYGEAQAWMDHMAQLGWSTLHNRHLVVERGGDRLVVAGVDDRTAG
                     SSGTGHRADHAAALAGADPDLPVLLLAHQPQQISLAVEHGVDLQLSGHTHGGQIWPFHY
                     LVRLDQPSVAGLTRHGDRTQLYTSRGTGFWGPPFRVFAPSEITVLTLRSGAA"
     gene            complement(16281..16838)
                     /locus_tag="Asera_RS32390"
                     /old_locus_tag="Asera_65130"
     CDS             complement(16281..16838)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65130"
                     /product="hypothetical protein"
                     /protein_id="WP_051801932.1"
                     /transl_table=11
                     /translation="MSLRLARTASEAYLYLARQPCEHCGATGFEPERSASEVIDGVLAR
                     RYSGACPSCGMWREYVFRVPDDASVPVDDGSGFGDATPSELLDPGEWLEIADAMFAQVP
                     DSPVGLTDEQRREAHAALGAGVAALAEVVKFIRPGADSVSPFAFWTERGRRFSLDSRWR
                     FDAERLRGELADARSALAGFAD"
     gene            complement(16835..17467)
                     /locus_tag="Asera_RS32395"
                     /old_locus_tag="Asera_65140"
     CDS             complement(16835..17467)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65140"
                     /product="hypothetical protein"
                     /protein_id="WP_157034684.1"
                     /transl_table=11
                     /translation="MSMPRARTRSEAYVYMDLVPCPCGENEFAPDVDVLDPEPPRVLRY
                     VGECPRCGRSREFVFELAEPPAAPPTGYVLGYGDEPSTIIDAGQWLLVAEMCRRVLEQV
                     ADSGESLTASQVPAVHDTVLLAAAAVDEIRKFLPAGAEELPADAFWTEQGRAVRSVAGE
                     LLRPDELAAARARRWAAVAEFEALYGIDEDDDADDEPSSARGDVNFR"
     gene            complement(17501..18721)
                     /locus_tag="Asera_RS32400"
                     /old_locus_tag="Asera_65150"
     CDS             complement(17501..18721)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65150"
                     /product="hypothetical protein"
                     /protein_id="WP_030445129.1"
                     /transl_table=11
                     /translation="MAEALGDAQVAARQALRRALLDVAAAACPDCAPVVERERGPFPVG
                     AQPASGNGDWACTVTVATAPPGMAWTAPELVRTAAEVLTAHGWTVGAEPTVTEGHRYEV
                     IAERPGGRVVASVRADDGILRLAGRCDAPPPEPAQPPRRAPRPDGWRPADDVQAALRLA
                     VERDDDRGYLELLLDAPLYLPSAAVDADAAAPRFATVTVDGGVHLVAFTGEPAPAPRGA
                     GWRVTTYQDLARSWPDPSWRLVVDPGTPIEAYLPAPSAEEADGTVRLPARPDPTAAATE
                     PFRPLNALEAALYEAVAADDRDAIFAALAADGAVVWMATGTGDLHPTDPGYVWPVVPLD
                     DGRAVCVYTASRRAADALGEEVEVAPVELAEVAAAWPDRTYRLVVDPGGPLAVTVPGFV
                     LSTLVRR"
     misc_feature    18706..18720
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(18724..19317)
                     /locus_tag="Asera_RS32405"
                     /old_locus_tag="Asera_65160"
     CDS             complement(18724..19317)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65160"
                     /product="hypothetical protein"
                     /protein_id="WP_051801930.1"
                     /transl_table=11
                     /translation="MTPDRPALARTPAETRLRLELTECPACSDRETRWRLVSTATVAGV
                     ALERYAGRCGRCGTVREADFRSPEQAPPAEPDDIEPATLFGAGRPSELLDAAEWLEVAT
                     LTEAAADDTAGADGSPVAEPAQQRRARLEYARDAVVEAMRFLPADGDRVPADRLFSPLG
                     RQVLAADPRRLTRDWMRAVRDGYEVLLAEIDDRR"
     gene            complement(19314..19817)
                     /locus_tag="Asera_RS32410"
                     /old_locus_tag="Asera_65170"
     CDS             complement(19314..19817)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018731491.1"
                     /locus_tag="Asera_RS32410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_65170"
                     /product="hypothetical protein"
                     /protein_id="WP_244844124.1"
                     /transl_table=11
                     /translation="MDLHPCQRCGSVEVEWKSALVDAEGELARSYSGTCTCGALREFVF
                     RLPAPGSVPASGDRYHFGGDAPSELLDAGEWLWVADMTASDVPTDDPTAGLNALSIAVA
                     AMNEIIKFIPAGAEAVPDEAFWSERGRRVRDQEPGRFDRERLLVVRDSYWSSLAERQSR
                     GDRS"
     gene            complement(19910..20419)
                     /locus_tag="Asera_RS32415"
                     /old_locus_tag="Asera_65180"
     CDS             complement(19910..20419)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS32415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_65180"
                     /product="hypothetical protein"
                     /protein_id="WP_030445126.1"
                     /transl_table=11
                     /translation="MSEDAPTRVGFWSYATGVGRKVAEFTRQPDGSVAFRVLDRSWAGP
                     AQDYYDNGVPVLAGGARIPATVGDEFLRALLQPFRMTYYGFLDESDALPAAASGAAPDR
                     QAADSAGDQASDLPLTGVSDPDAVQLRPIGPARGLSVEDAYRVLSGLPPGPVEVPPLPD
                     ERRDRP"
     misc_feature    20457..20471
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    22922..22936
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
ORIGIN
        1 tcgtggtgcg ggctcgcccc gttccggccg gacgcgacga tggtgaaatc gacctgctcg
       61 tggccgtgct cgcgcagccc ggccgcgaga tcggcggcga tgtcgacctc ccgccgaccg
      121 gcgaaccgca ccccgaggac ctgctcgtac gtggcgtccg cgccggcgcc ggccgccgcc
      181 agccggccca gctcgtcggc ctccttcacc gcgcgcagca tcggcagcgc ctcggacagc
      241 cccgcccagc acagctccgg cacggtgcgc tgcaacccga gcaggtgcag cgaccaggcc
      301 gagtcggaga tgcccagccg gccggccgcc ggcagcaggt cggccagcag ccggtacggg
      361 tcgacgccgt cggtgaagtc ggcgaacgtg agggcggccg gtgccagctc cgcggccggc
      421 cgctccagcg tcggcaccac cagggtcggc gcggcatccg cgcggaccac cagcgcggtc
      481 agccgctcgg tgtccgccgg cggtgtgtac ccggacaggt aggcgaggtc cggacccggc
      541 gtgagcacca gcgccgccag ccccgccgct cgcgccgccg ccaccgcccg ctcgcaccgc
      601 cgccggtaca cctcggaccc gaacgccgtg ccccccatgc ttccccccgc ttctcgcacg
      661 ctgtaccccc tgccgcaacg gtactgagca ggcgggacgc cttgccgccg acgccacgca
      721 ccgggcacct cccccgccgg acggccggtg cggcggccag cagttcgcaa cacggatgcg
      781 ggccagcccg tcggcggcga tacttccggc gtgatcaacc gcagcaatcc gcccagcctg
      841 cacgcgccgg acggctacca ccacgtgacg atcgccgagg cggggcgcac cgcgtacctt
      901 gccgggcagt gcccggtcga cgccgacgac cagctcgtcg ggcccggcga cgtgctcacc
      961 caggtcgacc aggtggtggc gaactgcctg ctcgcgctgc gcgccgccgg cgccgaaccg
     1021 gaccaggtgg tgcgctcggt ggtgtacgtg gcgagcgacg agcagccggt cctcgtgtcg
     1081 gtgtgggagc ggctgcaggc gtcgccgctc gcgccggcgt tcaccaccgc gagcaccctg
     1141 ctcggggtca ccgcgctcgg ctacgccggc cagctcgtcg agatcgacct caccgcggcc
     1201 ctgtcgtgac ggcagcggac ggcaccgagg cgctgctgat cggcggccgt tccggcgtcg
     1261 gcaagtccag tgtcggctgg gagatcgccg cgctgctgaa agcggcggac gtggcgcaca
     1321 cctacgtcga gggcgacacg ctggaccaga cctggccgaa gccgcccggc gacgcgacgc
     1381 tcgccaccct caccgaggag aacctgcgcg cgctgtggcg caacttcgcc gcccgcggcc
     1441 agcgccggct catctacacc aacacctcgg cggtactcga cgccgacctg atccggcgcg
     1501 cgaccggcgc ggcgcgctgc atcggggtac tgctgaccgc gtccgacacc accaccctgg
     1561 gcaggctcgc ggcccgcgag atcggcagcg aactcgacct gcacacccac cgcagcgccc
     1621 agatggccga ccgcctggac cgcgacgccc ccagctgggt gcaccgcgtt cccaccgacg
     1681 gccgtaccgt cacggacatc gccaccgaga tcatcgggat caccacctgg agctgaggcc
     1741 acttctttgc gctgaggtgg gcccgaagcg ccggtgcccg gctcgcgcgc gttgctggcg
     1801 gcgtccccct gttcgcgctg cgtgcgctct tgttggtggt gtaaaggcca cctctgtttc
     1861 tcttttcacc cctcgtgggg ggaccgtggg gagcgggctt cgcccctccc cacacccctc
     1921 cccgtcaagg gggcagtcgc ccccttgaca atcccccacc ggaaaaccag agacgagatc
     1981 ctgaccccgc ctggcccgtt tcggaacgac ggggtgtcgg tgcggcctac ccatcgccgc
     2041 cggaccgcca cgccaaacca aacccccaac ccacctgcgg gccgccggga cacgaagcga
     2101 cgcgttgcga ggcgggcgtt gccgtgatgg acatgccggg ccgggccccg gtcttcttcg
     2161 acacgcactc ggcgtcgagg ggcatcgtca ccgggcctgg caaggggatg gccaagggga
     2221 atccccttgg cggggaagga gcgcgaggag ggggcgaagc cctctcctcg cattccccca
     2281 cgcggggtcc aagcgtgaac agaggtggcc tttacaccag caacaacaca gcacccccgc
     2341 gcggacacgg cgcttcggga gcacctcagc gcatagaggt gcgcactgac ctcaccgcac
     2401 ggcgcgaatg gactcccgca aagacgacat cgtggccatg atcgcggtcg gctcgtaccc
     2461 gcagtgcgcc atgcagttgg cacagcgcgg atcccggccc cggccgtact tctcccagtc
     2521 ggtgtcctcg accagctcgc ggtagctctt ggcgtagctg tcgcccatca ggtagcaggg
     2581 ccgctgccag ccgaacagcg agtacgacgg gattccccag gcggtgcagg cgaagtcgcg
     2641 cttgccctcg aggaagtcca ggaacgccgg cgagtggttg atccgccact tctcccggcg
     2701 cccgttggcg aacgccttgc ggaacagctc gcgggtctcc tccacgccga ggaagtggtc
     2761 ctggtccggc gccttctcgt acgcgtacgc cggggagagc atcatcccgt cgaccttcag
     2821 atcgttgttg aggtagtcga gcacctcgat gacggtctgc ggggtgtcgg tgttgaagaa
     2881 cgtggtgttg gtggtgaccc ggaatccccg gtcctgcgcc atcttgatgg cgtccaccgc
     2941 ctgcgtgaag acacccttct tcgcgaccga ctcgtcgtgc cgctcctcca ggccgtcgat
     3001 gtgcaccgcg aaagacaggt acggcgacgg gtgcagcttg tcgatcttgc gcgggatcag
     3061 cagcgcgttg gtgcacaggt agatgaactt cttgcgctgg atcaggccct cgacgatgtc
     3121 ctcgacctgc gggtgcatca gcggctcgcc gccggccagg cagaccaccg gggcgccgca
     3181 ctcgtcggcg gcggcgagcg cccgctccac cggcatccgc tgcttgagca cgtcgtgtgg
     3241 gtgctggatc ttgccgcagc cctcgcaggc gaggttgcag gcgaacagcg gttcgagctc
     3301 cagcgtgatc gggaacttct tgcgaccggc cagcttctgc cggaacaggt acgcgccgat
     3361 cttcgccgcc tgccggaacg ggatactcat cgccgcgcga ctcctttgct tccgtggtcc
     3421 tcggcccggc gcacgacccg cgaacaacca gggcacaccg gaccacccga agcggtcata
     3481 tctggactac cacagcgaac cggtgctgcg cagtggaagc gcgatgccgg caccaccgaa
     3541 cggtggatcc acagaccgtg cagagcgcga atccgggcag gtaccgccga agcctccgcc
     3601 ggcccgcccg gtccacggca cgatgggccg ggaacaccgt cgtgccgggc agtccggaca
     3661 tgggagggca cggtgacacg gcttcgtacg gccatcgcca cgctcgcggt actcaccgcc
     3721 gcggtcgcca cgaccgccgg gtgcaccggc gacggcgcgg acaccaggga cacgatcgcc
     3781 ggcccgacgc cggcggcgga ccggacggcg ctgtcgctct cggtacggcc gaaggcgcat
     3841 gccaccggcc tgccggtcag caccgagatc ggtgcgacgg tgaccggcgg gtcggtcgag
     3901 gaggtgcggc tggtcgacgc gcacggcaac cacgtcgacg gctcgctgcg gccggacggg
     3961 acgagctggg tgccggaccg cccgctggcg taccaccggc gctacaccgc gaccgtcgtc
     4021 gccgtcggcg cgcgccggca gcacgtcgag cgccgcacga cgttcaccac catgagcgaa
     4081 ccgagcaacc gcgtcggcac cggcatgtac gtgcaggacg gccagaccta cggggtgggc
     4141 atgccgatcg cggtcgagat cctgcgcgac gtgccgaaga acctgcgcgc ctcggtgcag
     4201 cggcggctgt tcgtgcacag cgatccgccg caaccgggcg cctggcactg gttcggtccg
     4261 cggcgcgtcg agtaccgtcc cgcgacctgg tggcagccgg gcacgaagct gaccgtacgg
     4321 atggcgctcg gcggcctgcc gatgggccac ggcggctacg gcgacaccga ccgcagcgcc
     4381 accgcccgca tcagctccga ccggatcgaa ctgcggatca ccaaccggcc caagcagatg
     4441 aaggtgtacc ggaacggcag gctggcccgc acgatgccgg tcagtctcgg caaggccgat
     4501 gcgccgtcct cgtccgggca catggtgatc atggacaagg ccgcgcacac cgtcttcgac
     4561 acccgcggca tcccgggcga gaactacgtc gcaccggtgg acaacgcgca gcggctcacc
     4621 tggggcggcg agttcatcca cgcggcgccg tggtcggtgg ccgaccaggg gcaccgcaac
     4681 gtgtcgcacg gctgcgtcaa catctccgat ccggacgcgg cgtggctttt cgcccgcacc
     4741 cacatcggcg atcccgtcac cgtgtcgggt accggcacca ggctcgcccc gggcaacggc
     4801 tggaccgact gggacatgga ctgggacacc ttcgtggccg gcagcgcgct accggtgccc
     4861 gactcggtgc gcaacgcgac cgcctacgac ccgtacccgc ggcgctgagc cgacccgggc
     4921 acgccggccc ctcccggccg agggccaggt ggccggtggc gggtcgcccg ggtaaggatg
     4981 aggatcatga aggcaatcgt gttcgaccgt cacggcggtc cgacagtact gcaactgacc
     5041 gaggtggcgg ttcccgagcc gggcagggga caggtacgca tccgggtgcg cgcggccggc
     5101 gtgaacccga tcgacggcaa gctgcgggcc ggcggcggct ggccgatcga gctgccgtcg
     5161 accccgggcg tcgagggcgc cggtgtggtc gacgcggtcg gtccggacac cgatggcttc
     5221 gcggtcggcg acgaggtgct cggccacacc gcgaccgggt cgtacgcgca gttcgcgctg
     5281 tcggaccggg tggtgcccaa gcccgcgggg ctgtcctggg acgtcgccgc ggcggtgccg
     5341 gtcgcggccg agaccgcgct gcgggtgttg cggctgctcg acctgtcccc gggggagacg
     5401 ctgctggtcc acggcgcgtc cggcagtgtc ggcagcctgg ccgggcagct cgcgcggcgg
     5461 cgcggcgtca ccgtcgtcgg taccgccggc gcggccggcc gggaccgcct cgggcggctc
     5521 ggggtcaccg cgatcgccta cggcgacggg ctcgtcgacc gggtccggtc ggtcgcgccg
     5581 cacggcgtcg acgcggtgtt cgacgcggcc ggccggggtg cgctgccgga ctccatcgcc
     5641 ctgcgcggtg ggccggagcg catcgtgacg atcgccgatc cgaacgcggc cgagtacggc
     5701 gtgctgttca ccggcggcag cgaggtgatg gtcgaaccgg ccgcgatcgc cgaggtggcg
     5761 aagcaggtcg ccgcgggcga tctgaccgta ccgatcgccg cccggtacca gctggccgac
     5821 gccgccgagg cgcagcggct cagcgacacc gggcacgctg gcggcaagat cgtcctcacc
     5881 gtcgactgac cggttcggcc ggcgcggcgg gcccggaccc ttacgcagcg ctgtgcgcac
     5941 aatcacacgc ggtttagccg tgcttgcccg ttatcgtgct ggttacgcct acgaggcaca
     6001 gcgggagccg cggatggacg gtacgcacct ggacctccgg ttcgccgacg tgctgcgctc
     6061 ctaccgcacc acggcccggc tcagccagcg ggagctggcc gaccgggccg ggctgagcgt
     6121 cggtgcggtg cgcgatctgg agcagggccg gcggcggacg ccacggcgca gcacggtccg
     6181 ccggctcggc gcggcgctcg ggctgcccgc gccgtcggcg gcgggaccgg accccgcccg
     6241 ccggttcgtg ctgcgggtgc tcggtcccct ggagttgcgg gtcggcggcc gggcggtccg
     6301 gctcggccca ccccggcagc gcgccgtgct cgggctgctc gcgctctgcc cgaacgcgct
     6361 ggtgcaccgc gaggagatca tcgaccggct gtgggcccgc gccgcgccgg cgaccgcggt
     6421 acatctcgta caggcgtacg tgagtcggct ccgggcgctg ctgctgccgg acgcgccgcc
     6481 ggagcggcgg cgagcggtgc tcgagtcgac cggggcgagc taccggctgc gggtccggcc
     6541 ggacggactc gacctgctgc ggttcggtcg gctgaccgaa caggcccgca ccgcggtcgc
     6601 ggccggcaac cacctgctgg ccggcgagcg ctacgaggcc gcgctgcggc tgtggcgtgg
     6661 caccccgttg gcggatgtcg acctgctccg cggcagcgca ccggttgcca cgttggccga
     6721 gcagcgcgtc gccaccgcca tccggtacgc cgaggccgcc gcccgtaccg gacggcacca
     6781 cccggtgccg cagctgcggc tgctcgccga cgccgacccg ttgcacgagg cactgcacgc
     6841 ccggctgatg ctcgcgctgg ccgccggtgg ccagcaggcc gcggccctgc gggtgtacgc
     6901 ggagatcagc gcccggctgg ccgaccagct cggcctgacc cccggcccgg agctgaccga
     6961 cgcccggctc caggtgctcc gcggcggcgc cgatccgcgg cccggcccgg ggtgaggcgc
     7021 cggccccggc gcccggacgc tgtcagccga gcccgtggtg gatgaggcgc agggtccgct
     7081 cggcgacgtg gtccgggtcc gcgccgccct cgacggcggc catggccgac tgcagcaggc
     7141 cgccgacgag ctgggccgtc agctgcgggg cggtggggct gagctcggcg atcgcttcct
     7201 ggagcggcag gtagtgcagc cggtggagtt cgtggacccg gtcgcggcat tcctggggta
     7261 gttcggcccg catcagggcg gccgccgggc ggtggaggcc ctgcgcggcg agccgaagct
     7321 cggcacgcac gaaggcgtcg atgtgtcccg ccgggtgctc gacggtgcgc agcgcctggt
     7381 cgcgggcggt gtcggcggcg gcgaaggcgt cctcgacgat ggccgccagg atggcggccc
     7441 cggaggggaa gtactggtag aagctggaac gggccaggcc cgcgcgggcg ccgaccgcgc
     7501 ccggggtgac cgcgccggcg ccctgctcga tcaggatgtc gatcgcggcc cggaccaacg
     7561 cggcacgttg ctgggcgcgg tgctcggcca ccgtggccgc gttgatcttg ggcatggcgt
     7621 gggcgcgcct ttcgcgaacg ggtcaggtca gtcggccgtc ccgcaggttt cggacccggt
     7681 cggccgcgtc cagtatctcg gtgtcgtggg tgaccatgac ggtggccgtg ttctgggcgc
     7741 gggtctgccg ggcgatcagg tcgacgatgt cgcgggagcg tgcccggtcg agcgcggagg
     7801 tcggttcgtc cacgaggagg atctcggggg cgaggaggag ggcacgggcc agtccgaccc
     7861 gctggcgctc gcccccggag agctggtgcg gacgccggtc ggcgcgggcg gtcatcccga
     7921 ccgcgtccag cagctcgtcg gcccgttggc gggccgaccc gtcgagacgg ccggcgatgt
     7981 gcgcggcgac gagcaactgt tccctggcgg tgagggaggc gagcaggttg gcatgctgga
     8041 agacgtagcc gatgtggttg cgtcggtgcg cggtgcgctg gccctcggtg agggtggtca
     8101 ggtcggtacc ggcgacgtgg acggttccct cgctggggct ctgcagcccg ccggcgacgg
     8161 cgaggaggct ggactttccc gaaccggacg ggccggtgag ggcgaggaac tcgccccgcg
     8221 cgacggtcag gtcgacccgg tcgagcgcgg tgacctgctg ggctccgctg cccagccgga
     8281 gggtgacacc ggccagtcgc agcgcggcgg gcagggtcgt gccgtccacg gtggtggcgg
     8341 tggccggggt ggtcggggtc atcggttggc tccgagggcg gtgagggcct gcaccttggt
     8401 gatgcgacgg atcgcgacgg cggctccggc cagaccgaga acgatcagca gggccgcggc
     8461 catggtcacc tggccggggt cgagggagaa gggcgccgac cggttcatcg ctcggcccaa
     8521 cgcgagaccg acgccggtgc cggcggcggt ggccagcagc aggacgacgg tgacctgcgt
     8581 cagtgcgtcg cgcaggaggt agccggttcc cgccccgatg gccttcagca gggcgatctc
     8641 ctggcggcgc tggatggtcc acaccgtgaa gaaggagccc acgaccaggg cggagatggc
     8701 gtacaggaag gcgcggatca gggtcatggt gctggattcg gcggtgtagc ccggggatgc
     8761 cgcgtaggtg cccgccttgt ccacgctccg cgtgccgagc cggcggtcgg ccgtggcggg
     8821 gtccacgccg ggtgcgagtt ggagggccac ggcggtcgcc tggtcggtgg ccgccgccgg
     8881 cagcgggccg gccagaccgt agtgcagctg ttgccagagc ggcagcggcg cgtacacgac
     8941 gccgatgtgg ccgaacgagg cgtgcccgat cgtgcccacg acggtcagct cggtgcccgc
     9001 ctgtccggcg gtcaaccggt cgccgatgcg cacgccctcc gcggcgatgt ccgcgctgat
     9061 caggacgccg ttcggggccg ccgacagggg ccgccccgac accggtgggg gcgccaggaa
     9121 cccgtcgggc tcgaccccga acacggcgag atccagctgc ttgccggccg aaccggccag
     9181 ccgtgcgtgg acgagctgct gcccgaacgg ctcggcccgg cgtacgcccg gttgggacgc
     9241 ccaggcttcc caggtggtct tcgtgacggt ggagcgggag aacagttctc cggtagcgga
     9301 cttgtcgaac gccaggtgcg tgacgggcag ggcgcgcagc gcggagacac cggagtcggc
     9361 gagcccgctg gccagcccgg acaggatgac gccgagcatg gcgatcaggg cgacgaccgc
     9421 gccgatgagc gcgaagcggc cgcgggcgaa ccgcaggtcg cggagggcga ggaacatcag
     9481 gcggactcac ccggtacgcc gtcggcgacc gcggcgacgg tctcgaacgg ctcgacggtg
     9541 ccggccatgc cctgggtgga gggtccgtgg gcggcccgga aggacggcga gcgcatccag
     9601 gcggtgaacg cgtcccgggt ggtgaactcc atcaccgcca cgtacacccc gccggcctgt
     9661 gcggggcgca gcaggcgcgc cccgagcagg ccgtccaccc cgggcagcgt ctcacccatg
     9721 ctcgccgtga atcgctcctc gaaggtggac tcctcgccgc ccgggaccgg gatccggttc
     9781 atcaccgtgt acatcgactg cgcacccatc tcctccgacc ggagggcacc ggagccggcc
     9841 cgaagatgcc gactcatgtg ttggcatcct agcgcatgtt cccgacacag gtgtcggcaa
     9901 gctttgcggt cggcgcctcg ccgcgggcgg cgaggaactc gacgcccggc ggcacgaggg
     9961 cgccaccggg cgcggcccac cgacccggtc gcccgttcac tcagccggag ctgccgttcc
    10021 ggccggcgac cggcgggtgc agggccagta ccgagggcac ccggtcgggg gcggcggcgc
    10081 gcagcaggcc gtagccgatg ccggcgagtc cgaccagcag cgccggattc tcgccaccac
    10141 cggccaagcc gcacacccag ccgcgctcgt cgagccggtc caggatcgcc gcggtctgcc
    10201 gcagcgccgt ctcgccggcg gcagcggccg cggcctcgtc gagcaccgca ggcgcggtgc
    10261 agaacaggtc gagcgcgccg agatcgccgt ggcacagcga gaagttccag ccgaacccgg
    10321 cggctgccgc ggtgtccagc gcggtgcgca gatcggcggt cagctcggcg acggtacccg
    10381 cgccgccgac gccaccgccc gcgctctggt ccgagccgag gtcggcgacg ccgagctcgc
    10441 gcgcggcggc gagcaggccg gtacgggaca ggccgaggcc gacggcgccg tgacaccaca
    10501 gcaccgggaa ggacgcctcg tgcgggatgc cggtacgcac gtccggccag ttcccggcgg
    10561 cggcgtcgaa cagcgaccgc tcgtacgcca gggccgccgc cgcggtgggc aggtaccgcc
    10621 ggtcgccggt caccgtggcg gcccgggcca gcgcccaggc cggcccggcg gccccgtgcg
    10681 cgaagccggc cagcggccgc ggcgagacgt cggccatcga cgccgcgcgc cagcccaccc
    10741 cggccggttg ccgctcggcg cgggcgcaca gctggtccgc gcaggcggcc accgcggtgc
    10801 ggaccgccgc ggacggccgg accgcgtgcc aggcggcgag cccggcgatc gaaccggccg
    10861 caccgctgat cacgtcgtac tcggcgtcgt cggtggcgag ctcgccgacg cccgcggcca
    10921 tgttgtcggc cagcgcggcc agctcctcgt ccggccggat cgcgtgcagg tgagccagcg
    10981 cgtacagcac gccgccgtag ccgcagaggc cgccggccag gttccggggc agccggagca
    11041 cctgggcacg cagggtgtcc agggcgcccg cggctgccgc ccggtgcgcc gcgtcgccgg
    11101 tcacctcggc cagccgggcc aggaacaacg tcacgcccgc ggtaccggag tacaggtcgg
    11161 cgcccagcgg cgccagcgcc cacgcaccgc cgggcagcag cccgggaccg gcccaggcga
    11221 ggctgccgtc ccgccggtac gcgagggcca ccaggcggtc cgccgcccgc ccggcgtact
    11281 ccagcgcgcg ggccgcgacc cggtcggccg ccggcagcgg cgcggccggt accaccgcgg
    11341 cgacggtgcc gtcggcctgc ggcacgtggt cggttcgcga cgactcgacg gcccagcgca
    11401 gcagcgaccg ctgggcggcc aggtcgtcct cccccagcgc gtcgagcttg gccagcgcga
    11461 ggctgagcgc cggctcgtcg gaaaccgccg gcagcttgcg accggcggcg tcgcacagcg
    11521 cggtcccgcc cggccgcgcg gtgaacaccg gtacgtcggt ggcggccagg tcggcgcgct
    11581 cggacgccag cagcggcgcg accgcctcca gccgaggtac cagttcccac agccggtcca
    11641 agtgccggtc ggcggcgagc ccgtcgcgca gccggtccgg gtgcagcccg gccaccacca
    11701 gggtgcggta ctccatcgtc tcccggcaca gcacccggat ctcgtcgtcg gcgaacgcgt
    11761 cgagcagctc gcgcaccgcc tcccggtgcc cggcgagaat gcggtaggcc tcggtgaagc
    11821 cggcgtcgag atcggcgcgg aagtcggcca accgcagcgg ttcgcccggc ggcagcggcc
    11881 gggacgcgac ctgcccgatg ccgacccggc ggtaccccac ccgcacctcg tcggtaccgg
    11941 cgtcccgcag ctccgggatc tcccgcggcg gcagctcgcg cgggtcccag cccagcgccg
    12001 acacgtcggc gccgccgtta ccgacctcca cccaggcccg gtacggcagc atgcccgagc
    12061 gcagcaccga accgccgatc gcggtgttgg ccaccagctc ggcggcggac agctcgtgca
    12121 gatcctcacg cagccgcggc gtcagcagcg tctcgtggtc gatcagcacc ggctggtcac
    12181 cgaccgcgat caggttctgc gcgtggcagt cggtcgcctc cagcaggtac agcagcgcgg
    12241 tcagcgtgcc cgcccggtgg tagaagcggt gcaggtcggc gccgtccgag cagtaccgct
    12301 gctgcacgtg cgcgacccag ccgtagccgt cgcgcgccag gcagggcagc tcggcgagcg
    12361 gccaccgcag gtacccgttg agccacgcca ccagctgctg gtagtgcgcg tcgacggcga
    12421 gcgaccgcgg cttgtacagg atccgtacgc cgtgctcgaa gcgcagccgg gccaccgtgc
    12481 ggccgccccg atgccggtcg ccaaggtcgg tctccagctg cgtcactgcg ccgagcggtg
    12541 caccgccggc gaaccgggcg gacagctccg gcaggtccgc gacgagccgg tgcaccagct
    12601 ccgcgctggc ggtcacccag ttgcggcaca cggtcaccag ccggcgcgcc agcaccgggt
    12661 actcggcgag caggcccgcc gcgatccccg gatcccgcag ccggtccagg aactgccggt
    12721 accggccggt gggggtgtcc gcggtcagcg caccggtcac cttcgccacc tgcacctcga
    12781 gcaccatgct gcgctgggtc agcgcgtacg cgtgtgcggt cagcgacggc aggaaccggg
    12841 cgacggcggc gtccgggtcg ccgaacgggg tgtcgccgag cggggcgagc gcggtacgca
    12901 gccggccggc ggcggcagtc agcagcggcc cggcgaccgc ggcgaggtcg tgctcggcgg
    12961 gcagctcgat cggggccggc gtggcgaacg cggccaccag ctcgtccacc cacgagccac
    13021 cggcaacctc ggcggtggcg ccggcgtggc cgagacccac gcggtcggcc agcgcgtccg
    13081 gcggctcggc gagctggtcg tgtaccacct ccacggtcaa cccgtccgca gccagccgac
    13141 ggtcgaacca gcccgccttg tggaacggcg gctgggcgcg ccagcgggcc atgatgcggt
    13201 cggcgcgggc cgaccggccc ggatcgacga ccgccggctt gccccgttcg accgccgaca
    13261 acgcctggct catggcccgc cgcagcgcga ccagagctgc ctccacccga cctcccaccg
    13321 gccgacctcc caccgatcag ggctcccacc gatcacgggc cgtcccgacg tccccggccg
    13381 cggttgcctc ccgccagccg ccgccggacg gccgctgcgt tccgagaacc gggccgcatc
    13441 gcggccggcg gcgggcagcg cggcctcgcg ctgcccgccc ggccggtcag gccgcgcagc
    13501 tgcagatgtg tgcacaggtg acgctggcgt agttgcaggt ggacgccgcg ccggtggaca
    13561 cgtacagctc gcggtcgacc tctcccgccg gatgtgctac ggcggactcc aactcgagcc
    13621 ggaagtcctc gtcccgccaa gcgcggacca gttcttctgc cgacatggaa cctccctcgt
    13681 gacgaagcgt gcggtgcggt acgcgcccag tattcgcacg gtggttggtg ttccgtttgg
    13741 cgttgcgctc acggcaattg ccgtaccgcg ccgttcggcg aggtgggacg ggggaaccgg
    13801 ttccggcccg gcggccggga gactgggtgt tgagccggcc cggagatcta ggtgctgggg
    13861 cgggccaggc agcggaagcc gatgtgcgac atcgccgact cgacctgctg cgcctgccgg
    13921 gccgccggcc ggtaccgccg gcagtagttc tccgcgcaca ggtgcgagcc gcccttgagc
    13981 acccgccgcg gtacgtgcgc gccgccctgc tcctggtcgc cgtagctgcc ctcggcgtcg
    14041 tccacccgcg gattgacggg cggcgcgcag caggcgtgcg tggccggatg gttgctgcgg
    14101 tagaagtccg cggtccactc ccacacgttg ccggccacgt cgtacagccc gtacccgttc
    14161 ggcgggaacg atcgcaccgg ggtggtgcgc tgccgccgcg ccggtttgag gttgtgccag
    14221 gggaactcgc cgacccaggt gttggccatc cgcttgccgc cgggcaggaa ctcctcgccc
    14281 caggcgtacg gcgcgccgtc cagcccgccg cgcgcggcga actcccactc cgcctcggtg
    14341 ggcagctgct tgccggccca ctgtgcgtac gcctcgacgt cctcggcgca cacgtgcacc
    14401 accgggtggt cgtcgcggcc ggtgacgtcg gagcgcggcc cctccggatg ccgccagctc
    14461 gcccccggca cgtaccgcca ccactgctgc atgtcggtca ggtcgaccgg cttgtcggtc
    14521 ggggtgaaca ccagcgaacc ggccagcagc agccggcggt cgacgttcgg gtactgcgcc
    14581 gggtcgagcg gccgctccgc cactgtgacg tatccggtgt cggtgacgaa ccgggcgaac
    14641 tgcaccaccg tgaccggggt cgggtcgatc cagaacccgt cgacggtgac gcgatgcggc
    14701 ggcccctcct ccgggtagtc ggcgaggtcc gagcccatcg tgaacgtgcc gcccggcacc
    14761 cacaccatcg ccgggtccgg cggttgctct cccgctgtca tgacgccagc tacgttacgc
    14821 ggcgccggag cgcagggtca ggacggtgat ctcgctgggc gcgaacaccc ggaacggcgg
    14881 gccccagaag ccggtccccc ggctggtgta cagctgggta cggtcgccgt gccgggtcaa
    14941 ccccgcgacc gacggctggt ccagccggac caggtagtgg aacggccaga tctggccgcc
    15001 gtgggtgtgc ccggacagct gcagatccac cccgtgctcg accgccagcg agatctgctg
    15061 cggctggtgg gccagcagca gtaccggcag gtccgggtcg gcgccggcga gcgccgcggc
    15121 gtggtcggcc cggtgcccgg tgccggacga gccggcggtg cggtcgtcga ccccggccac
    15181 caccagccgg tcgccgccgc gttccaccac cagatgccgg ttgtgcaggg tcgaccagcc
    15241 cagttgcgcc atgtggtcca tccacgcctg cgcctcgccg tagtactcgt ggttgcccgt
    15301 cacgtacgcc cgggccagcg tggcccgcac gtcaccgagc ggcgcggcct gcgccagccg
    15361 ggcgttcacc gaaccgtccg cgatgtcacc ggtgtggcag acgatgtccc cgtccagctc
    15421 gttgaccacg tcgatcaccc ggcgggacca gtcggcccgg tcgatcgggc cgtagtgcgt
    15481 gtcggtgatc agcaccaccc gcagcccgtc caggccggcg ccgagccggt ccagccggac
    15541 cgacacctcg gccacccgcg gcagccgcat cgcctcgacg tacccccagg ccagcagcac
    15601 gatcgtgatg accaggccga ccgcggcgac gacccgggac accgcggtgc cggacaggtc
    15661 ggtggcgagc agcgggagcc ggaccagctg tgccagcgtg caccagacga acagcacccc
    15721 gatcacgccc agcagcacgt cgctggtgcg ggccgcgggg tcgttcgcgc gccggtggcc
    15781 caggttcatc agcaccggga acccgatcgc ggccgcgacg aacagcaccg taccgacgac
    15841 cacgacgccg gtcggccagc cgggcgcgag caccagcgtc caccacgaca ggccgaacag
    15901 cagcacctcc accgccacca gcacggcggc gaacgccacc acccggccga tccgtctgcc
    15961 gggctcggcc cgtacatcct cggttgccgt cactacacac tccgtatcca tctcgcgccg
    16021 cgcccgcccg ccgcgcaccg cacgagcatg acaccccaac ctgagaccag cccacgacgc
    16081 ccgcggtacc cggcttcgac ggccggcggc cgtgcgccac ggaccgtcgg ccccgctcct
    16141 gccgcgccgt ccgggcacag ccggacgcca cgggcaccgc accaggggca ccacctgggt
    16201 caacacctgg gtcaacaccg cgaacaacgt gggtgtcgcg atcggcggtc cgctgagcgt
    16261 gggatgcggg cgagtccggg tcagtcggcg aagccggcca gcgccgaccg cgcgtcggcc
    16321 agctcgccgc gcagccgctc ggcatcgaac cgccagcgcg agtcgaggct gaaccggcga
    16381 ccccgttcgg tccagaacgc gaacggcgag accgagtccg cgccgggccg gatgaacttc
    16441 acgacctcgg cgagggctgc gacgcccgcg ccgagggcgg cgtgcgcctc ccggcgctgc
    16501 tcgtcggtca gcccgaccgg gctgtccggc acctgggcga acatcgcgtc ggcgatctcc
    16561 agccactcgc ccgggtcgag cagctccgac ggcgtcgcgt cgccgaaccc gctcccgtcg
    16621 tcgaccggca ccgaggcgtc gtccggcacc cggaacacgt actcgcgcca catcccgcag
    16681 gacgggcagg cgccggagta ccgccgggcg agcacgccgt cgatcacctc cgacgccgac
    16741 cgctccggct cgaacccggt cgcaccgcag tgctcgcacg gctggcgagc caggtagagg
    16801 tacgcctcgg acgcggtccg ggccagccga aggctcatcg aaagttcacg tctcctcgcg
    16861 ccgatgacgg ctcgtcgtcc gcatcgtcgt cctcgtcgat cccgtacagc gcctcgaact
    16921 ccgcgaccgc ggcccaccgc cgcgcccgcg ccgccgccag ctcgtccggg cgcagcagct
    16981 ccccggccac cgaacgcacc gcccgaccct gctcggtcca gaacgcgtcc gccggcaact
    17041 cctccgcgcc ggcgggcagg aacttgcgga tctcgtccac ggccgccgcc gccagcaaca
    17101 ccgtgtcgtg cacggccggg acctgcgagg cggtcaacga ctcgcccgag tctgccacct
    17161 gctccagcac ccgccggcac atctccgcga ccagcaacca ctggccggcg tcgatgatcg
    17221 tcgacggctc gtcgccgtag ccgagcacgt accccgtcgg cggcgcggcc gggggctcag
    17281 ccagctcgaa gacgaactcc cgggaccgac cgcagcgcgg gcactcaccg acgtagcgca
    17341 gcacccgcgg cggctccggg tcgagcacgt cgacgtccgg ggcgaactcg ttctcgccgc
    17401 acgggcaggg caccaggtcc atgtagacgt atgcctcgct cctggtgcgg gcacgaggca
    17461 tcgacatgcc gccaccatac cgggcacggt cgatcgacca tcagcgtcga accagggtcg
    17521 aaagcacgaa accgggcacc gtcacggcga gcggcccgcc cggatccacc accagccggt
    17581 acgtccggtc cggccacgcg gccgccacct cggccagttc gaccggcgcc acctcgacct
    17641 cctcgccgag cgcgtcggcg gcccgccggg acgccgtgta cacgcagacc gcgcggccgt
    17701 cgtcgagcgg caccaccggc cacacgtacc cgggatctgt cgggtgcagg tcgccggtgc
    17761 cggtcgccat ccagacgacc gcaccatcgg ccgcgagcgc cgcgaagatc gcatcccggt
    17821 cgtcggcggc caccgcctcg tacagcgccg cctccagcgc gttcagcggg cggaacggct
    17881 cggtggccgc cgcggtcggg tccggccggg ccggcagccg caccgtgccg tcggcctcct
    17941 ccgccgacgg cgccggcagg tacgcctcga tcggcgtgcc ggggtcgacc accagccgcc
    18001 agctcgggtc cggccagctc cgcgccaggt cctggtaggt cgtcacgcgc cagccggcac
    18061 cgcggggtgc cggcgcgggc tccccggtga aggcgacgag atgcaccccg ccgtcgaccg
    18121 tcaccgtggc gaaccgcggg gccgccgcat ccgcgtcgac cgccgccgac gggagataca
    18181 gcggcgcgtc cagcagcagc tcgaggtatc cgcggtcgtc gtcgcgctcg acggccagcc
    18241 gcagcgccgc ctgcacgtcg tcggccggcc gccagccgtc cggccgcggg gcccgccgcg
    18301 gcggttgcgc cggctccggc ggcggcgcgt cgcagcgccc agccagccgc aggatcccgt
    18361 cgtcggcccg caccgacgcc accacccgcc cgcccggacg ctccgcgatc acctcgtacc
    18421 ggtgtccctc ggtcaccgtc ggttccgccc cgaccgtcca gccgtgcgcg gtgagcacct
    18481 cggcagcggt ccggaccagc tcgggcgcgg tccacgccat cccgggcggg gcggtcgcca
    18541 cggtgaccgt gcacgcccag tcgccgttcc cggaggccgg ctgcgcgccg accgggaacg
    18601 gtccgcgctc ccgctcgacc accggcgcgc agtccgggca tgccgcggcc gccacgtcca
    18661 gcagtgcccg gcgcaacgcc tgccgggccg ccacctgagc gtcgccgaga gcctcggcca
    18721 tgctcacctc cggtcgtcga tctcggccag cagcacctcg tagccgtccc gcacggcccg
    18781 catccagtcc cgggtcagcc gccgcgggtc ggccgcgagt acctgccggc ccagcgggga
    18841 gaacagccgg tcggcgggca cccggtcacc gtcggcgggc aggaaccgca tcgcctccac
    18901 cacggcgtcg cgcgcgtact ccagccgggc gcgacgctgc tgcgccggct cggccacggg
    18961 gctgccatcg gccccggcag tgtcatcggc ggccgcctcg gtcagcgtgg ccacctccag
    19021 ccactccgcc gcgtccagca gttccgaggg ccggccggcg ccgaacaggg tcgccggctc
    19081 gatgtcgtcc ggctcggccg gcggcgcctg ctcggggctg cggaagtcgg cctcccggac
    19141 ggtgccgcac cggccgcagc gccccgcgta ccgctccaac gcgacgccgg ccacggtggc
    19201 ggtggacacc aaccgccacc gcgtctcccg atcggagcac gccgggcact cggtcagctc
    19261 cagccgcaac cgcgtctccg ccggggtccg tgccagcgcc gggcggtcgg gcgtcacgac
    19321 cggtcgccgc gcgactgccg ctcggcgagc gaggaccagt agctgtcccg aaccaccagc
    19381 agccgctccc ggtcgaaccg gcccggctcc tgatcccgca cccgacggcc ccgctcggac
    19441 cagaacgcct catcgggcac cgcctcggcg ccggccggaa tgaacttgat gatctcgttc
    19501 atcgccgcca ccgcgatgga cagggcgttc agaccggcgg tcggatcgtc ggtgggcacg
    19561 tcgctcgcgg tcatgtccgc gacccacagc cactcgccgg cgtccagcaa ctccgacggc
    19621 gcgtcgccgc cgaagtggta ccggtcaccc gaggccggca ccgaaccggg cgccggcagc
    19681 cggaacacga actcccgaag cgcgccgcac gtgcaggtcc ccgagtagct gcgggccagc
    19741 tcgccctcgg cgtccaccag ggcgctcttc cattccacct cgaccgagcc gcaccgctgg
    19801 catggatgca aatccatgta caggtgtgcc tcgtcccgcg tccgcgcaag ccgcaaagcc
    19861 atccgtcaac cctagttcga ccccgccacg ccgcgccgcg ccggctcgtt cacggacggt
    19921 cccgccgctc gtccggcagc ggcggcacct cgaccggccc gggcggcaga ccggacagta
    19981 cccggtacgc gtcctccacg gagagcccac gggccggccc gatcggccgc agttgtaccg
    20041 cgtccgggtc gctcaccccg gtcagcggca ggtccgatgc ctggtcgccg gcgctgtccg
    20101 cggcctggcg gtccggcgcg gcgccactcg ccgccgccgg gagggcgtcg ctctcgtcga
    20161 ggaagccgta gtaggtcatc cggaacggtt gcagcagcgc ccgcaggaac tcatcgccta
    20221 cggtggcggg aatccgggca ccgccggcca gcaccggcac accgttgtcg tagtagtcct
    20281 gggcggggcc ggcccaactc cggtcgagca cccggaatgc cacggagccg tccggctgcc
    20341 gggtgaactc ggccaccttg cgcccgacgc cggtggcata cgaccagaaa ccgaccctcg
    20401 tcggcgcgtc ctcactcatc gaccaacccc gcgatctcga cgctcgcctc gaccccgtct
    20461 cgttcggcga acacgatcat gccgttctcc tggacctccc ggagccgggc gaggccggca
    20521 tcgatcgcgg ccgtcccgat cccccggctc tccagccttg cacgcaactc gtccgggtcg
    20581 attccccgta cccgggccag cagatcggcg ttcagcctgg tccgcagctg ggcctcgacg
    20641 aacggcgaca ggatctggtc ccgggcagat tccgacagca ccagaccgtg atcgatcgcg
    20701 accaccgacc cgtcccgggt gaggaaattg aactggttac ggtcagtgtt gcccagcacg
    20761 tagtcgatga ccgcgacctc ctgctgttcc cgccacgggt actcctcgac cggccggtgc
    20821 gcctgcgctt cctcgaccca ccgctgcagg gagccctgca tgcctcgtat ctcgacgggc
    20881 acggtcggcg gcaccagggt ggatccgagc agctcggcga agtccgaggc gccgacctcg
    20941 cgggcggcga gctggccggg tacctgcggg ataccggccc ggatcacctg gccgtccttg
    21001 acgaagacct cggcctcggc cggtttgaag gcgcccacca cccgatcgtg ctggaaggcg
    21061 cggtacgttc cgttgacacc gctcttcatc ccggcggcga gaccctccag ccggtcgacc
    21121 ggctgaccgg ccagctccgc tcgggccgcc gccacggcgg caacctccgg cgaccgggcg
    21181 ggcatcccgt cgccgccggc cgcgagatcc gccgcgagct gctcgaaccg ccgggcctgg
    21241 aagtcgtgcc aatccgccca gccacgcacc tgctcggcct cgaactccgc gtcccgagcc
    21301 cacgaatgat gctgccagcg atccgcgaag gactccatca gggcggtcag ccggtcggcc
    21361 cggcggttca gccggtcggc gtcggcgcgc aggacggccg cccgctcctc ggcttggccc
    21421 gcggcgttca gctcctcggt cacccgttcc gggccggccg tgccctgccg gttcaacacc
    21481 tgggccgccg cgatccggga cgccgcctcc tgatccgcac gtccggcctc ccggcccagc
    21541 tcctccactc gggcccgcac cgcggccagg tccgcgcgga cccggcggac cgtggtcccg
    21601 gtcgcaccgt ccgaaccgga caccgtccgc tgcagcgccg cggcgagctc gtagtgctcg
    21661 atcgccgcgg tcagcagctc gacccgacgc tcgtgccggt ccgcgtgctc cgccgatcgt
    21721 tcggcgtcca ggccggtgaa gacccgtacc gaggaggact caccgaccag ctgcgacaga
    21781 tcccggcgca gcagatcggc gtggcggtcg agccgatccg ggtactggtc ctccctctcc
    21841 tgtgcccggg cggacagctc ctgtgcccgg cgctcggcgg cgtcggccgc ggcctcggcc
    21901 gacagcgcct cctgctcggt ccggccggcg tcctccgccg ccgcgtggta cgcctgctct
    21961 gccgccgccc ggcgcgcatc gaggtcgagc aacacctgcc gatccgccgc ggaccaccgc
    22021 tgcagctccg ccaccgcctg gcgcgatcga gcgagccgct gctcggcctg ctgctgttcg
    22081 gccagcgtcc ggtcgaactc cgacacctcg gcccgggcgg cctgggcggc ggcgcgctcg
    22141 atctcggcct gggaccggtg gtactccgcc gagtaccgcc ccgcgtcgtc ctcgggctgg
    22201 tccgggtgcc ggcgaagctg ctccgcgtgg aacgcgagtc gccgctcgtg ctcggtgagg
    22261 cgctgctgcg cttcctcgcg cgcgccggcc gccgcggtgg ccgccgccga cgaccggcgg
    22321 tgctgctcgg cagcgacgct gttttcctgg gcccactcac ggagattgcg gtcggtctga
    22381 gcgagccggt ccgacacggc gtgctgctcg gaccgcgccc gtgccagctc cgcgtccacg
    22441 gatgccagcc gacgctggtg gtccgcgagg cggatgcggt gccaggtcgc ggccgaccgc
    22501 tcctcggccg cgatcgcctg ctggtccacc gcttcgtcac gccagctcgc gatccggccg
    22561 cgatccggac ccggctcggc gccctcgacc ggcgtccggg cgggcgcctc ggccggcacg
    22621 ggtggttcgg ccggcgcgga tggttcggcc ggcgcccgcc cgccgtcggg taccggtcgg
    22681 ggctcgttcg gcgtcggttc cggccgcggt gccggctcgg agtgcgtccc gccgacctct
    22741 ccctggccga ccacccgggc ccgcagcacg tactgcacct cgccctggaa gtggcgcact
    22801 tccaggcgga ggccgacgat ccgggtgccc ggtgccagca gaacctcggc ctgttccgga
    22861 cgtgggctga tccggccgag ccaggcgagc cgggtgccgg ccggcacctc cagctccagc
    22921 tggatcttct cggcctggaa gccggctcgc tcggcggcgg aggtgggcat gaatcccggg
    22981 tccgcgattt cccggccgag cagcccggcc agttcggcgg ggctggtgat gccgagcgcg
    23041 ccgaggctca tcccgcgccg gagcagcagg tcctcggcgc tttcccgcat gccctggtcc
    23101 atcgcctcgc acaccggcgc gtactcggcg aactgcggca ggtgttggcg ctgccatccg
    23161 ttgatgccga agtagttgcc gtcgaggtag gtgtcgtacg ccgtgcgcgc ctcggtcggc
    23221 cagtcaccgc cctgtgccgc gtgcacccgg tccatgtcgg tggcgtccgt accgtccggg
    23281 aaccgtgcgc tgctgtcggg cagcgg
//
