LOCUS       NZ_AP023354            20954 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Actinocatenispora sera strain NBRC 101916 chromosome.
ACCESSION   NZ_AP023354
VERSION     NZ_AP023354.1
KEYWORDS    RefSeq.
SOURCE      Actinocatenispora sera
  ORGANISM  Actinocatenispora sera
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinocatenispora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Actinocatenispora sera NBRC 101916
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7044238)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 251x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018324685.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 04:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,585
            CDSs (total)                      :: 6,501
            Genes (coding)                    :: 6,404
            CDSs (with protein)               :: 6,404
            Genes (RNA)                       :: 84
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 26 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 1 of 97
            Pseudo Genes (multiple problems)  :: 10 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:48:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3545763
            Orig. end                         :: 3566717
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="11"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10954)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(257..841)
                     /locus_tag="Asera_RS16955"
                     /old_locus_tag="Asera_33920"
     CDS             complement(257..841)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085752.1"
                     /locus_tag="Asera_RS16955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33920"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_030445596.1"
                     /transl_table=11
                     /translation="MRSISVTMFISLDGVVQGLGRPDEDTRGGFTHGGWGPRYTDEVMS
                     RELAQGMARPGDMLFGRRTWEDFTAAWGRATDGNPFTAHMNAATKYVVSRSLPDANAWQ
                     NSILLRGEAVETVGALKEQPGTDLSINGSASLVRSLHAAGLIDRYTLLIHPLTLGSGMR
                     LFDGPAPLTELELTGSVTTGTGVIIAHYARR"
     gene            complement(921..1496)
                     /locus_tag="Asera_RS16960"
                     /old_locus_tag="Asera_33930"
     CDS             complement(921..1496)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020511586.1"
                     /locus_tag="Asera_RS16960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33930"
                     /product="GNAT family protein"
                     /protein_id="WP_030445597.1"
                     /transl_table=11
                     /translation="MLRGTKVSLRARHEADVAVLHAELYDDVAIRSRADTRPWRPAADT
                     ASPFAVSEPSADAARFSVVELASDELAGSALLWGIDPHNRRAHLGMSLRPGYRGRGLGT
                     DVVRVLCRYGFETLGLQRLQVETLADNAGMLHAAERVGFVREGLLRRSLWVAGDFADEV
                     LLGLLAAEYDPGRTPGSPPATEDPGEHR"
     misc_feature    1528..1541
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            complement(1825..2046)
                     /locus_tag="Asera_RS16965"
                     /old_locus_tag="Asera_33940"
     CDS             complement(1825..2046)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS16965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_33940"
                     /product="hypothetical protein"
                     /protein_id="WP_030445598.1"
                     /transl_table=11
                     /translation="MTGNVGVDGLVDGTVLTEADGEALPLGEALPLGEALLLGDGLALV
                     VDGDGLGDPYPPGEDGLGEDGIDGLGEP"
     misc_feature    complement(2012..2027)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            2233..3201
                     /locus_tag="Asera_RS16970"
                     /old_locus_tag="Asera_33950"
     CDS             2233..3201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013731851.1"
                     /locus_tag="Asera_RS16970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33950"
                     /product="DNA polymerase ligase N-terminal
                     domain-containing protein"
                     /protein_id="WP_035296150.1"
                     /transl_table=11
                     /translation="MREYRRRRDPTRTPEPMPTATPAGGHGDTFVIQQHDATSLHWDLR
                     LERDGVLVSWAVPRGLPAEPGVNRLAVHTEDHPLEYSTFEGTIPAGEYGGGTMTIWDTG
                     TYQTEEWRADKVTVALAGSRVQGRYTLFATDGKNWLIRRLDPPQDPDRAPMPREIEPMQ
                     PVRQAHPPREADRYAYEFDWGGKRAVAFVSGGRIRLHGADGTEIESPAGLPRAARRLGA
                     RPVVLDGELVTLAADRVFVGFDLLYDDGIDLTGWPQQQRWDRLDALPWWGGSCQLAPRF
                     DDPAAVRATARERGLPGIVAKRRDAPYRPGATSAAWKRIPA"
     gene            3479..4948
                     /locus_tag="Asera_RS16975"
                     /old_locus_tag="Asera_33960"
     CDS             3479..4948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473762.1"
                     /locus_tag="Asera_RS16975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33960"
                     /product="NF041680 family putative transposase"
                     /protein_id="WP_030450043.1"
                     /transl_table=11
                     /translation="MISVPQPYRRVVGGQLSRFRRDFYACLTSRADGLFEACDALLCVD
                     GPVRSLPELSLAGVHRRGHGGLYGALAAGRIDSDRLRQAMLGCTLPRAGDGRIVLAVDV
                     TCWLRPEAHTSPGRMMCHTYGRGKDQHIGVPGWPWSVVVALETGRSSWTAPLDAVRLAP
                     GEDAAAVTAYQLRRVVTGLIEAGHWDAGDPEILIVADAGYDGPRLSFVLADLPVRVLVR
                     MRSDRVLRRAALSDRRHTVGRPCRHGSEFVFGQTATWGEPDVQISTDTRHYGPARIRAW
                     DRLHPRLTHRTAWAAHTGDLPVLEGTVIRLDVERLPSGAIPKPVWLWHSATDLDPGQVD
                     LAWQAFLRRFDIEHTFRMLKQTLGWTCPKLRDPAAAERWTWLVLAAYTQLRLARNVAAD
                     LRRPWEKPLPPQRVTPARLRRGFRYLHPRLPPLAAAPKLCRPGPGRPAGHPNQRPAARH
                     DVHTASRPDRPKPHRHKPKKPSATPRPRRTG"
     gene            5275..6075
                     /locus_tag="Asera_RS16980"
                     /old_locus_tag="Asera_33970"
     CDS             5275..6075
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463157.1"
                     /locus_tag="Asera_RS16980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33970"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_030449808.1"
                     /transl_table=11
                     /translation="MSGQGSDWTPDGVDDSRPNAARMYDYFLGGAHNFEPDRQLADTLL
                     SIAPEIRDIARANRAFLQRAVRWLAAAGIDQFLDLGSGIPTAGNVHEIAQRLDPNSRVV
                     YVDTEPVAVSHSKLLLADAPHVAVLQADLLDPAAVFTSPEVTGLLDLDRPIAILLVSVL
                     HFFGDEQRPGALVADYLARTAPGSYLAISHVTPNEHSEQVRTLYQHTTDRLYPRSKAEI
                     AALLDGFPLVPPGLVRLGDWHPDTIVAGAEADRAASYAAIAERR"
     gene            complement(6107..7906)
                     /locus_tag="Asera_RS16985"
                     /old_locus_tag="Asera_33980"
     CDS             complement(6107..7906)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="Asera_RS16985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33980"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_051803078.1"
                     /transl_table=11
                     /translation="MAELEFRVLGPVQAWRAGQPVPLGGNRVLTLLAGLLLSPNEVVSW
                     HRLAEWVWGDQPPSHPRSALHNGISRVRQLLGRSVIQTQGSGYQLVTDAAHHDLLLFDQ
                     LTTAAADAELRGATEAAVDLLSEALALWRPPLLGNLDASALYRHTIDHLTDRYLDAHEE
                     RARLCLRLGRHAELIVELSDLVRANPFRETLAGQLMLALFRSGRRADALMVYQQLRQVL
                     RDELGVDPGTTIRDLHSEILRTESAVPAREPGPPMPVHCTSGSTPVAQVPPRQLPAPSG
                     RLIGRDPQLAALDDWLAAGDSTLAAVVGPAGAGKTALALWWANRIRGRFPDGQLYLDLG
                     GYGDAPPLRVEDSLAILLGALGVPTDAVPTEIRSAGALLRSMLAERQVLVVLDNARDSD
                     QIRPLLPGGGSTAATVVTSRKQLRGLVARDGAHRVEVAELEADAAAELLCAAAGLSPGS
                     LTPQVTTDLVQRCAGLPLALRIIGERIARTGVAMPGEPTTVSGLDVLSTHEGTDTDLAA
                     VLDWSYRALDAKTAAAYRQLGRYPGTELRVEDAPAVFGGSADVASRMLDTLAAMYLVQQ
                     RGAGRYEWNDLIRRHAARCADLA"
     gene            complement(7974..10004)
                     /locus_tag="Asera_RS16990"
                     /old_locus_tag="Asera_33990"
     CDS             complement(7974..10004)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="Asera_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_33990"
                     /product="NAD(P)-binding protein"
                     /protein_id="WP_030449806.1"
                     /transl_table=11
                     /translation="MIADVAVLGAGPAGCVLATVLARAGRSVLLIDHPPAPADHDLYVS
                     GPAEADLSSLDIELAGHHVDAVDLRLRPDSCRRVTGTGGRVMPVGALRATLRTAAIEAG
                     AQPLPGVGTVTGQLDGVHRIRVDGLSVLVSVQARHLVLAVGCAPNGGREGAANSPSGGG
                     QPTGSMVSVRVSGMPDDTDAVLLALAVPTMQQRVPVSVWLLPTGAGAGTLGVACPVPTT
                     RPLDPAQLLAVGRATLTELDARYAGLTDAGKAQAGRLHTGFSRQRLVAANGLLIGAAAG
                     LANPFTGETLGYAVHSARLAAAAIGTHPDDPAAARRHYVQRAAARFLGRFEIARHATRR
                     HHLTWRVLSAAADSDQPFFAKTRRAVLLPSGVTGAVATGADLDPVDASFAMPFLLACDE
                     VLVRTVQTTWPFLAQLATSDGTLGGQQLRPALLFLAGLTASTRVPPSRRATTAAAVELA
                     MLGALAFLWQPGARPSGRGIDWAQTATVLSGDFLLAQASRLIAESAPEVSWAFADWLAD
                     LTHLRARGRGPEVALDVYGSLFEFPARIGTYLGGGVASTVRAMQEFGNRYGRAFLHTED
                     VLAVRGEPTRLDTTWAAMRSGGFTAVPAQVGGVHVSESTLRDDPGLRAAVLARARAAGR
                     REAAAAAAAADLTDETARRLATHSLAALTSPLRHESGTSGT"
     gene            complement(10001..10954)
                     /locus_tag="Asera_RS16995"
                     /old_locus_tag="Asera_34000"
     CDS             complement(10001..10954)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="Asera_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34000"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_051803077.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.6e-47, bitscore:
                     158.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVTATVSARARAEFIALTGARLGELTAAVPEPLGTPVRALAERP
                     GKRLRSVLLHAAAVGATNPHLVRLAALVELLHLASLLHDDVVDRGTSRRGAPSARATVG
                     DELATLAGLACFALAGREAAELGDGLETVVARAAAGLAYGEILDVERAFDIDLSLPDYL
                     ELVERKTGDLFRLSCSLGAAAAGADSGTLAASGRFGAELGVAFQILDDCLDLATIESGK
                     PVGTDHLLGLFGAPTLFALAADGTGELATLLLDPAFDRDDLPAVRAHVTASGGLAAAHE
                     LAQDRYQIALAALDGVDSPRRTSLTEVAAMIWPESA"
     misc_feature    10983..10998
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.61"
                     /tool="antismash"
     gene            11193..12452
                     /locus_tag="Asera_RS17000"
                     /old_locus_tag="Asera_34010"
     CDS             11193..12452
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="Asera_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34010"
                     /product="S53 family peptidase"
                     /protein_id="WP_211255815.1"
                     /transl_table=11
                     /translation="MAAAALLAVVGLAVAPPSASAAPPPMPLVAPPQLPDNARPVCGPV
                     LPGYVHCDAFVRTDSAGSDPTDPQEPAAGEPVPSAYRPADLQDAYGLPSATAGGGQTVA
                     VVDAYDDPKAESDLAVYRAAFGLPPCTTANGCFHKVNQRGETKNYPAPDRHWGMEISLD
                     LDMVSAICPRCHIVLWEADQASQEDLAAAAHLAGCDCTSPAGTNYGARYVSNSYGGPEA
                     GFSASVDDSYRSDKGTVYTVSSGDSGYGVEYPASSKWVTAVGGTSLLPADNARGWDEIA
                     WLYGGSGCSTYVAKPAWQHDGGCSGRSVADVAAVADPTTGVDMYDSYETVDYNGPWLVN
                     GGTSAASPIIAGVYALGAKVLPGTIPSTYPYAKFTQLNDIVGGTNSFENCSPEYLCNAG
                     PGYDGPTGYGTPHGVAAFQE"
     misc_feature    11994..11996
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12492..14120)
                     /locus_tag="Asera_RS17005"
                     /old_locus_tag="Asera_34020"
     CDS             complement(12492..14120)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_34020"
                     /product="hypothetical protein"
                     /protein_id="WP_030449803.1"
                     /transl_table=11
                     /translation="MKLEPMVFDADVQASLIRAQRKLFRVFRDDPHFTGAAIGMRHRAG
                     DYVDEPVVIAMVRKKLAEGQIPLHRMVPATIEVDGRRWGVDVVEVRPLRHPGLPAVANA
                     SYRPGPDAGAAKPNAVNDPIRKKFTDPVQGAGISNATGSLSGTLGCFVRDLDNNDGRIC
                     FLSSNSVLARVDQPAFGEAIYQPARQDGGGSNDAIGTVRRFSELGTTATVDAAIGVLNS
                     GVTADLGVADGLMAPISATHPAIGMITASDTDPLQRHVNSFISRMDHIVDALHVELSVA
                     DDEHSCIAAPQLFSHIEKVGHASGYTSSMVTALAAIVKIDYGFKYVTLTDQIWSQAFCL
                     PGDSGALVLAGGNGRTFVQEPEPPTSNCELLATVGHYYDLPLADDNDLTSQARDQFLAQ
                     SPLGNLLIGAIYLNQQTVIDRLGGKEAEGVAIGYAKEYYDKYRTLVATVLANPDSGATM
                     TQENIDDLEFMFAGMTGGAGIQPVLDQDEAQVAYTLLTGVVANTVGMNYQQIIDYMNDP
                     GVFQTVYDQLATLPSVNIVGPVVAG"
     gene            complement(14117..14593)
                     /locus_tag="Asera_RS17010"
                     /old_locus_tag="Asera_34030"
     CDS             complement(14117..14593)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_34030"
                     /product="hypothetical protein"
                     /protein_id="WP_157035216.1"
                     /transl_table=11
                     /translation="MTTAVAVGTGGAPADASAGALSAEQCEMVLRIAAAGAVYPIPFPS
                     FAESGSAVSRATMARLQTAWGKVGSARSKLVQAGANALIEADPADDPALRGAITALARG
                     DQATTVTATVALAVATISTHFDPNSDSAAQLWIGGLRRLPAGPDRVPSPARRIR"
     gene            complement(14825..16018)
                     /locus_tag="Asera_RS17015"
                     /old_locus_tag="Asera_34040"
     CDS             complement(14825..16018)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027798.4"
                     /locus_tag="Asera_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34040"
                     /product="beta-1,3-glucanase family protein"
                     /protein_id="WP_030449801.1"
                     /transl_table=11
                     /translation="MSDTPVPRRSLLRGLALGAIGAPLVAAFGAPSVAAAGTRGPFADG
                     TLAVTVTNDSGAAGNDAVRLYVVGTDLATGAQAHADAGGNLIPVSLSDNGSDGYTDYSI
                     PLAGSGDTTIALPHMSGRIYFALGDPLRFKAVPDGNGNPALAYPAGWVESDPNYPVLHD
                     FFEFTYDGSGMHCNNTQVDMFGVPSSVHLVGAADQTTGTLEAGGRGRIFAEVAAQAGFG
                     SLVLDDLRVIAPGHGIEVGRFAADYFDGYLDDVWSKYAGETLTVHTGGADRTGRVTGGV
                     FTFDGAVAPISKPTTSDVFFCAGALAAPNDGLTGPVAAALGAGFNRSTLLASASQPTDD
                     PAGFYATDPTNHYARIMHAHMTDGRAYGFPFDDVGGFASYIEDGAPTALHLTLTAFS"
     gene            complement(16056..17075)
                     /locus_tag="Asera_RS17020"
                     /old_locus_tag="Asera_34050"
     CDS             complement(16056..17075)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692631.1"
                     /locus_tag="Asera_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34050"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_244843916.1"
                     /transl_table=11
                     /translation="MDIDELARRSGVSAATVSRALNGRPEVSAATRARIVALAAELGYR
                     PNASARTLASRRSGLIGLLWDTGYRSGGRQHPFLQEVLIGLKAALSDRGQGLILLPIVP
                     PDDEDGYVRLARQYTLDGIVMMGVDQHTPQVRALLATPVPCVGLDLALDGPRTASVGSD
                     NRTAAADAVAHLHALGHRRIATITGPLDLWPAAERLAGFRAELARRRLRRRPGYEVTGD
                     FFAASGAAGMRRLLDLPTPPTAVFVAGDAMAIAAMRAAADAGRTLPGDVAVVGFDDIDA
                     AAMVRPGLTTIAQDYRRFGTTAAAVLAELAAAPATEPSRSVLLPTRLVVRESSGGTAT"
     gene            complement(17245..17595)
                     /locus_tag="Asera_RS17025"
                     /old_locus_tag="Asera_34060"
     CDS             complement(17245..17595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020511654.1"
                     /locus_tag="Asera_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34060"
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="WP_030449799.1"
                     /transl_table=11
                     /translation="MRTTLRRDLTAALKARDRVAVSALRSALAAIDNAEAVPAPDSPTS
                     DAEHVAGAVVGVGAAEAARRELTADDLHAIVAAEVAERVDAATGYARSGRAEAADRLRA
                     EADVLRRYLRPE"
     gene            complement(17681..18907)
                     /locus_tag="Asera_RS17030"
                     /old_locus_tag="Asera_34070"
     CDS             complement(17681..18907)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018738385.1"
                     /locus_tag="Asera_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34070"
                     /product="MFS transporter"
                     /protein_id="WP_035298796.1"
                     /transl_table=11
                     /translation="MTGYRQVLGVPGMAPLLAVSLLARTAITAAGMALTLYVVLGLHLG
                     YAAAGAVPASLTAGLALGGPLLGRLIDRRGLRTALLATVVTQAGFWLALPALRYPVLLG
                     AAFVAGLLMVPAQAVTRQAIAALSTGGQRRPAFALESVQGELSYLVGPAAVILAAATLS
                     PATMAWGIGGAIVVGGAALAALDPPLRSPDEAPAGTAPRPPRREWLGAGMIAVLVLAFG
                     IALLLGGIDLAIVATLRQAGQVSWASLVVAVCGLASVTGGLCYGMLNRPLPTWLLLGLL
                     GVATVLAGLAPSWPWLCLAVVGTGLLTAPTLSTVADAVSRLAPAGVRGEATGLQASAMS
                     AGVALGAPVVGWTIDASAPAAGFAAAGLAGLLAALAGHLLSRRARRPRHRDIHPEIAAP
                     RPEPCQAKL"
     misc_feature    complement(18626..18628)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18980..19822
                     /locus_tag="Asera_RS17035"
                     /old_locus_tag="Asera_34080"
     CDS             18980..19822
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="Asera_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_34080"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_030449797.1"
                     /transl_table=11
                     /translation="MARELETALLRSFVTAVRAGSISRAATQLGQTQPGISQQLRKLER
                     AVGHPLLHRSSAGVAPTRAGEELLPYAERILALATQALAETGHALSGHCGIGLLEDLAA
                     SHLPQALADLARLHPDATLEVLSLSSATMREAYDAGRVQLVLDELPYLPGPPRWTVRRP
                     LAWAVGHGVELTADPLPVVLFSGTCTWRSSVLEALSQVDRRWRIAFESDSLAGVLAALR
                     AGLGVSALLPANLEPGMVCHDQAALPALPDVELGLTRHPRTDGDPLIDAVAAVLRRMV"
     misc_feature    20508..20522
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(20732..20747)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.33"
                     /tool="antismash"
ORIGIN
        1 ccggtgggcg cgcagcggct gctggccccg ctgttgcggc cgctgctcgc ccggacgctg
       61 cgcggcgatc tcgatcgcct ggccgccctg ctggccgccg atcactgacg cccgccatcc
      121 gccgaccgcc gcccgccgac cgccaccgct gagggccgcc ggccgccgac ccgccgcccg
      181 ctgacggccg ctgcccgccg gcgatcgggt cggtgggcac ggtggcgaac gacggaccga
      241 ccgggtcggg acgcggtcag cgccgggcgt agtgcgcgat gatcacgccg gtaccggtgg
      301 tgacgctgcc ggtgagttcg agctcggtga gcggcgcggg accgtcgaac agccgcatgc
      361 cgctgccgag cgtgagcggg tggatcagca gggtgtagcg gtcgatcagg ccggccgcgt
      421 gcaggctgcg gaccagcgag gcgctgccgt tgatgctcag gtcggtgccg ggctgctcct
      481 tcagcgcgcc gaccgtctcg acggcctcgc cgcgcagcag gatcgagttc tgccaggcgt
      541 tcgcgtcggg cagcgaccgg gacaccacgt acttggtcgc cgcgttcatg tgcgcggtga
      601 acgggttgcc gtcggtcgcc cgcccccacg cggcggtgaa gtcctcccag gtgcggcggc
      661 cgaacagcat gtcgccgggc ctggccatgc cctgggcgag ttcccggctc atcacctcgt
      721 cggtgtaccg ggggccccag ccgccgtggg tgaagccgcc gcgggtgtcc tcgtcgggcc
      781 ggccgaggcc ctggacgacc ccgtccaggc tgatgaacat ggtgacgctg atcgaacgca
      841 tcgttcctcc cgcggttccg gccggagtca cccgccgggg cgcgggcgac ggctgaacag
      901 acgaccggcg ggccgggaac tcatcggtgc tcgccggggt cttcggtggc cggcggcgag
      961 ccgggagttc ggccggggtc gtactcggcg gcgagcaggc cgagcagtac ctcgtcggcg
     1021 aagtcgccgg ccacccacag cgaccggcgg agcagccctt cccggacgaa gccgacgcgc
     1081 tcggcggcgt ggagcatccc ggcgttgtcg gcgagcgtct cgacctggag ccgctgcagg
     1141 ccgagcgtct cgaagccgta ccggcacagc acccggacca cgtcggtacc gagaccccgg
     1201 ccgcgatacc ccgggcgcag cgacatgccc aggtgcgccc ggcggttgtg cgggtcgatg
     1261 ccccacagca gggcggaacc ggcgagctcg tcgctggcca gttcgacgac cgagaaccgg
     1321 gccgcgtccg ccgagggctc ggacaccgcg aacggggagg cggtgtcggc ggccgggcgc
     1381 cagggccggg tgtcggcacg ggatcggatc gcgacgtcgt cgtacagctc ggcgtgcagg
     1441 acggcgacgt cggcctcgtg ccgggcgcgc aggctcacct tcgtacctcg caacatgacc
     1501 gcttcctacc cgacggcggc gtcgaacggc accgaatttg cccatcgcgc ggcaccgtcc
     1561 cgggtgcaca ccccgcagac cacgacatac gtcgaccctg agtaaccatt cgtggcgtgc
     1621 ttcgttgcgt tcggtgagat caacggcctg atcaaggaga agtatgcgta cgtcccgcgc
     1681 gctggcggtg gccgcactgg ccgccgggac cgtcctcgca ctggggtcgc cggccgtcgc
     1741 cggttattcg acgccgccct gcgccggcaa cggctacggc cacccgtcct gcccgtcgac
     1801 gcccggtccg tcgacgcccg gcggttacgg ctcgccgagc ccgtcgatgc cgtcctcgcc
     1861 cagcccgtcc tcgcccggcg ggtacgggtc gccgagcccg tcgccgtcga ccaccagcgc
     1921 cagcccgtca cccagcagca gtgcttcccc gagcggcagt gcctccccga gcggcagtgc
     1981 ctcaccgtcg gcctcggtca gcacggtgcc gtcgaccagc ccgtcgacgc ccacgttgcc
     2041 ggtcaccggt ggcggcatcg ggctgctcgc cggggccgcc gcggtgctgc tcgccgccgg
     2101 cggctgcgtc tggttgctgg cccgccgccg ccgcgcctga ccgtaccctg aaggcggggc
     2161 gcccggcggc gcccgagccc gtggaggggg gacgggatgc cgcgacggcg gagtgcgggc
     2221 accgaccagc cgatgcggga gtaccggcga cgccgcgacc cgacccgtac gccggagccg
     2281 atgcccaccg ccacaccggc cggcggccac ggcgacacgt tcgtgatcca gcagcacgac
     2341 gccaccagcc tgcactggga cctgcggttg gagcgcgacg gcgtgctggt gtcctgggcg
     2401 gtgccgcgcg gcctgccggc cgagccgggg gtcaaccggc tcgccgtgca caccgaggac
     2461 cacccgctgg agtactcgac gttcgagggc acgatcccgg ccggcgagta cggcggcggc
     2521 acgatgacga tctgggacac ggggacgtac cagaccgagg agtggcgcgc cgacaaggtc
     2581 accgtggcgc tggccggcag ccgggtgcag ggccggtaca cgctgttcgc caccgacggc
     2641 aagaactggc tgatccgccg gctcgacccg ccgcaggatc cggaccgagc gccgatgccg
     2701 cgcgagatcg agccgatgca gccggtccgg caggcccacc cgccgcgcga ggcggaccgg
     2761 tacgcctacg agttcgactg gggcggcaag cgggcggtcg cgttcgtgtc gggagggcgg
     2821 atccggctgc acggcgcgga cggtaccgag atcgagtcgc cggccggcct gccccgcgcc
     2881 gcccggcggc tgggcgcgcg accggtggta ctcgacgggg agctggtcac gctcgcggcc
     2941 gaccgggtgt tcgtcggctt cgacctgctg tacgacgacg ggatcgacct gaccgggtgg
     3001 ccgcagcagc agcggtggga ccggctcgac gcgctgccct ggtggggcgg cagttgccag
     3061 ctcgcgcccc ggttcgacga ccccgccgcg gttcgcgcga cggcccggga acgcggcctg
     3121 cccggcatcg tcgccaagcg ccgcgacgcc ccgtaccgac ccggcgcgac ctcggcggcc
     3181 tggaagcgca tccctgccta gggtctgttt cgcaagtccc gcgtgccggc tgcggcggcc
     3241 ccgtttgccc gctcgcggcg ttgtcggaca gcccgtgtgc aagcccggca cacgaactgc
     3301 cctccgcctt gcgagcagac aaacgcgact cgcctcgctc ggccgggggc tccgaaacag
     3361 accctagctt gagttttaac cttggtgggc ggtgtggggc accctggttg atcatggaag
     3421 cagcccttgg ttgatcattc ctcttgcgac agtaggaaga tcaacagcaa gggctgcggt
     3481 gatcagtgtg cctcaaccat atcgtcgggt cgtcggcggg cagttgagcc ggttccggcg
     3541 ggacttttat gcgtgtttga cgtcccgggc cgatggcctg ttcgaggcgt gtgacgcctt
     3601 gttgtgtgtc gatgggccgg tgcggtcgtt gccggagttg tcgctggccg gagtccaccg
     3661 ccgtggtcac ggtggtctgt atggcgcgct ggcggctggc cgtatcgact ccgatcggtt
     3721 gcggcaagcg atgttggggt gcacgttgcc gcgggcgggt gatgggcgga tcgtgctggc
     3781 ggtggacgtg acgtgttggt tgcggcccga ggcacatacc agtcccggcc ggatgatgtg
     3841 tcatacctac ggtcgtggca aggatcagca catcggggtg ccgggctggc cgtggtcggt
     3901 ggtggtggcg ttggagaccg gacggtcgtc atggaccgcg ccgttggacg cggtccggtt
     3961 ggctccgggt gaggacgcgg cggccgtgac cgcttaccag ctacggcggg tcgtgaccgg
     4021 cctgatcgag gcagggcatt gggatgccgg tgatccggag atcctgatcg tggccgacgc
     4081 cggctacgac ggtccccgcc tgtcgttcgt gctggccgat ctgccggtgc gggtgctggt
     4141 gcggatgcgt tccgaccggg tcctacgccg agcggctctg tctgatcgtc ggcatacggt
     4201 gggccggccg tgccggcacg gcagcgagtt cgtgttcggc cagacggcaa cctggggcga
     4261 gcccgatgtc cagatctcca ccgacaccag gcattacggg ccggcgcgta tccgtgcttg
     4321 ggaccgtctg catccgcggt tgacgcaccg caccgcctgg gccgcgcata ccggcgatct
     4381 gccggtgctg gaaggcaccg tcatccgcct cgacgtcgag aggctgccct cgggcgcgat
     4441 cccgaaaccg gtgtggctgt ggcattcggc caccgacctg gaccctgggc aggtcgacct
     4501 ggcatggcag gcgttcctgc gccgcttcga catcgagcac accttccgca tgctcaaaca
     4561 gaccctgggc tggacctgcc cgaaactacg cgacccggcc gcggccgaac gctggacatg
     4621 gctggtgctg gccgcctaca cccaactacg cctcgcacga aacgtcgcgg cggacctgcg
     4681 tcggccgtgg gagaaacccc tcccgccaca gcgggtgacc ccggcacgcc tccggcgagg
     4741 gtttcgatac ctgcacccgc ggctgcctcc tctagcggct gcgccgaaac tctgccggcc
     4801 cgggccagga cgcccagccg ggcaccccaa ccaacggcca gccgcccgcc atgacgtgca
     4861 cacggcgtcc agaccggacc gacccaaacc gcatcgccac aaacctaaga agccgtcggc
     4921 cacgccacga ccccgacgaa caggttaaaa ctcaagctag gggcacttcc ggctggcgag
     4981 ctgacccgtc ccgccggccg atgcaacagg accgggcggc ttgtcagctt cggtgtccgg
     5041 tacacggcgg tgagccagga gacctgcctg atcgcctggc ccgacccggc gcaccgggac
     5101 cgcctgctgg tcttcgatcg cagggcggtc cgctgaccac acccggcgcc gtccccgggc
     5161 tcggcgcgcg tcgcggggcc gctgcccacc gtgcccccgg caccgtggcg cacgggctac
     5221 cgtcggtacc gtggctgctc ggtcaccgtg gtcgggcacg acggagggcg gacgatgagc
     5281 ggacagggct ccgactggac gccggacggg gtggacgact cccgcccgaa cgcggcccgg
     5341 atgtacgact acttcctcgg cggggcgcac aacttcgaac cggaccggca actggcggac
     5401 acgctgctga gcatcgcgcc ggagatccgc gacatcgccc gggccaaccg ggcgttcctg
     5461 cagcgtgcgg tgcggtggct ggcggcggcc gggatcgacc agttcctcga tctcggctcc
     5521 gggatcccga ccgccggcaa cgtgcacgag atcgcccagc ggctcgaccc gaacagccgg
     5581 gtggtgtacg tggacaccga gccggtcgcg gtctcgcaca gcaagctgtt gctggccgat
     5641 gccccgcacg tcgcggtgct gcaggcggac ctgctcgacc cggccgcggt gttcacctcg
     5701 ccggaggtga ccgggctgct cgacctcgac cggccgatcg cgatcctgct cgtctcggtg
     5761 ctgcacttct tcggcgacga gcagcgaccc ggtgcgctcg tcgccgacta cctggcccgt
     5821 accgcgccgg gctcgtacct ggccatctcg cacgtgacgc cgaacgagca cagcgagcag
     5881 gtccggacgc tctaccagca caccaccgat cggctgtacc cgcgttcgaa ggcggagatc
     5941 gcggcgctgc tggacgggtt cccgctggta ccgccgggac tggtgcggct gggcgactgg
     6001 caccccgaca cgatcgtggc cggcgccgag gccgaccggg ccgcctcgta tgcggcgatc
     6061 gccgagcgcc gctgacccgg cgtgcggggc gtccgccggc cgacgttcag gcgaggtcgg
     6121 cgcagcgggc ggcgtgtcgt cggatcagat cgttccactc gtagcggccc gcgccgcgct
     6181 gctggaccag gtacatcgcc gccagcgtgt cgagcatccg ggacgcaacg tccgctgacc
     6241 caccgaacac cgctggcgca tcctcgaccc gcagttcggt gcccgggtag cggcccagct
     6301 gccggtacgc ggcggcggtc ttcgcgtcga gcgcccggta cgaccagtcc aggacggcgg
     6361 cgagatcggt gtcggtgcct tcgtgcgtcg acagcacgtc gaggccgctc accgtcgttg
     6421 gctcgcccgg catggcgacc ccggtacggg cgattcgttc accgatgatg cgcagtgcca
     6481 gcggcagccc ggcgcaccgt tgcacgagat cggttgtgac ctgcggggtt agtgatccag
     6541 gggagagacc tgcggcggcg cacagcaact cggcagccgc gtccgcctcc agctcggcca
     6601 cctcgacgcg gtgcgcgccg tcccgggcga ccagaccgcg cagctgcttg cggctggtga
     6661 ccacggtggc ggcggtggac ccgccgccgg gcagcaacgg tcggatctgg tcgctgtcgc
     6721 gggcgttgtc gaggacgacg aggacctggc gctcggcgag catgctgcgc agcagggccc
     6781 cggccgaccg gatctcggtc ggtaccgcgt cggtcggtac acccagtgcg ccgagcagga
     6841 tggcgagcga gtcctccacc cgcaggggcg gtgcgtcacc gtaaccgccg agatcgaggt
     6901 agagctgtcc gtccgggaac cggccccgga tcctgttggc ccaccagagc gcaagcgccg
     6961 tcttgccagc gcccgccgga ccgaccacgg ctgccagggt gctgtccccg gccgccaacc
     7021 agtcgtcgag cgccgccagt tgagggtccc gcccgatcag ccgaccgctc ggcgcgggca
     7081 gctggcgcgg tggaacctgc gcgaccggcg tcgaaccgga ggtgcagtgc accggcatcg
     7141 gcggacccgg ctcccgggct ggtacggccg attcggtgcg caggatctcc gagtgcagat
     7201 cgcgaatcgt ggtgccagga tcgacgccca gctcgtcgcg cagcacctgc cgcagctgct
     7261 ggtagaccat gagcgcgtcg gcccgccgac cgctgcggaa cagcgcgagc atcaactggc
     7321 cggccagggt ctcgcggaac gggttggcgc gcaccagatc cgacagttcg acgatgagct
     7381 cggcgtggcg accgagccgc aggcagagtc gggcccgttc ttcgtgggca tccaggtacc
     7441 ggtcggtgag gtggtcgatc gtgtgccggt acagcgccga cgcgtcgagg ttgccgagca
     7501 gtggcgggcg ccacagggcg agcgcctcgc tcagcaggtc caccgcggcc tccgtggcgc
     7561 cacgcagttc cgcgtccgcg gcggcggtgg tgagctggtc aaacagcaac aggtcgtgat
     7621 gcgccgcgtc ggtaaccagc tgatacccgg aaccctgggt ctggatgacg gagcggccga
     7681 gcagctggcg gacccgtgag atgccgttgt gcagcgcgga gcggggatga ctcggtggct
     7741 ggtcgcccca cacccactcc gcaagccggt gccaggagac gacctcgttg ggcgacaaca
     7801 gaagcccggc gagcagcgtc aggacacggt tgccgcccag gggtaccggc tggccggcac
     7861 gccaggcctg gaccggtccg agaaccctga attccagctc tgccacggca ccatcatcct
     7921 cgggggaaag tctgcgtttc gtgcgcacca cgtggatgaa agcgggcagc gcgctatgtg
     7981 ccagatgtgc ctgattcatg acgaagtggc gaggtgaggg ccgcaaggct gtgtgtggcc
     8041 aggcgccgtg ctgtctcgtc ggtcaggtcc gccgcggccg ccgcggcggc ggcctcccgc
     8101 cggccggctg ccctggcgcg cgcgagtacg gctgcgcgta ggccggggtc gtcgcggagc
     8161 gtcgattcgg agacgtgaac cccgccgacc tgtgcgggta ccgcggtgaa cccgccggat
     8221 cgcatcgccg cccaggtggt gtcgagccgc gtgggttcgc cgcgaaccgc gagtacgtcc
     8281 tcggtgtgca ggaacgcccg gccgtagcga ttcccgaact cctgcatcgc ccgcacggtg
     8341 ctggccacgc cgccgccgag gtacgtcccg atgcgggcgg ggaactcgaa cagggagccg
     8401 tagacgtcca gtgccacctc gggcccgcga ccgcgcgccc gtaggtgcgt caggtcggcg
     8461 agccagtcgg cgaatgccca ggacacttcg ggcgccgact cggcgatcag gcgcgacgcc
     8521 tgcgcaagca gaaagtcgcc ggacagcacc gtagcggtct gcgcccagtc gataccgcga
     8581 ccggagggtc gggcgccggg ctgccagagg aacgccaagg caccgagcat ggcgagctcc
     8641 accgcggcgg cggtggtggc ccggcgggac ggcggtaccc gggtcgaggc cgtcagcccg
     8701 gccagaaaca gcagcgcggg gcggagttgc tgacctccca acgtgccgtc ggatgtggcc
     8761 agctgggcca agaacggcca ggtggtctgc accgttcgga ccaacacctc gtcgcaggcg
     8821 agcagaaacg gcatggcaaa cgacgcgtcg acggggtcga ggtctgcacc cgtggccacg
     8881 gcgccggtga ccccggacgg cagcaggacg gctcgccgcg tcttggcgaa gaacggctgg
     8941 tcgctgtcgg cggcggcgga cagcacgcgc caggtcaggt gatgtcgccg ggtcgcatgt
     9001 cgggcgatct cgaagcgacc caggaacctg gcggcggcgc gttgcacgta gtggcgtcgc
     9061 gccgctgcgg gatcgtccgg atgcgtgccg atcgcggcgg cagcgaggcg tgcgctgtgc
     9121 accgcgtaac ccagggtttc accagtaaac gggttggcca agccggccgc cgcgccgatc
     9181 aggagtccgt tcgccgcgac gagccgttgc cgggaaaagc cggtgtgtag ccgaccggcc
     9241 tgggcctttc ccgcgtcggt cagtccggcg taccgggcat ccagctcggt cagtgtggcc
     9301 cggccgacgg ccagcaactg cgccggatcc agcggccgag tcgtcggcac cgggcaggcc
     9361 accccgagcg tcccggctcc ggcaccggtc ggcaacaacc agacactcac cggtactcgt
     9421 tgctgcatgg tcggcacggc cagcgccaga agcacggcgt cggtgtcatc cggcatgccc
     9481 gacacccgga ccgacaccat cgagccggtc ggttggccgc ccccgctggg ggagttcgcc
     9541 gcgccctccc gaccgccgtt cggtgcgcac ccgacggcga gtaccaggtg ccgggcctga
     9601 accgacacca gcacggagag gccatcgacc cggattcgat gcacaccgtc gagctggcca
     9661 gtgacagttc ccacgccggg gaggggctgg gcacctgcct cgatcgcagc cgtgcgcagg
     9721 gtcgctcgca acgcaccgac cggcatgaca cggccgccgg tgccggtgac ccgccggcac
     9781 gaatccggtc gcagccgcag atcgaccgca tcgacgtgat gccccgcgag ctcgatgtcc
     9841 agcgacgaca gatcggcctc cgctggacca ctcacgtaga ggtcatgatc ggcgggcgcc
     9901 ggggggtggt cgatcagcaa caccgaccgc ccggcccggg cgagcaccgt cgcgaggaca
     9961 catccggccg ggccggcgcc gaggacggcg acgtcggcga tcatgccgat tcgggccaga
    10021 tcatggccgc cacctcagtc agcgaggtac gccgcggcga gtcgacgccg tcgagcgcgg
    10081 ccagcgcgat ctggtagcgg tcctgggcaa gctcatgcgc cgcggcgagg ccaccactcg
    10141 cggtcacgtg cgcccgcacc gcgggcaggt cgtcacggtc gaacgccgga tcgagaagca
    10201 gcgtggcaag ttcgccggta ccgtcagcgg ccagcgcgaa cagggtcggc gcaccgaaca
    10261 agccgagcag atgatcggtc ccaacgggct tgccggactc gatcgtcgcc aggtccagac
    10321 agtcgtcgag gatctggaac gccacaccga gctcggcgcc gaagcgcccg gacgcggcca
    10381 gcgtgccgga gtccgcgccc gctgcagcgg caccgagcga acagctgagc cggaacaggt
    10441 cgcccgtctt gcgttcgacc agttccaggt agtccgggag ggacaggtcg atgtcgaagg
    10501 cccgctccac gtcgaggatc tccccgtacg cgagtccggc cgcggcgcgt gcgaccaccg
    10561 tttcgaggcc gtcaccgagt tccgccgcct cccggccggc cagcgcgaag cacgccagac
    10621 cggcgagggt cgcgagctcg tcgcccaccg tcgctcgggc gctcggcgca ccgcgccggc
    10681 tcgtaccccg gtcgaccacg tcgtcgtgca gcagcgatgc caagtggagc agttccacca
    10741 gcgccgcgag ccggacgaga tgagggttcg tggcgccgac cgcggcggcg tgcaggagca
    10801 ccgagcgcag ccgcttgccc gggcgctcgg cgagcgcgcg cactggtgta cccagtggtt
    10861 cgggcactgc cgcggtaagt tcgccgagcc gggcccccgt cagcgcgatg aactccgcgc
    10921 gcgcccgcgc tgagaccgtt gccgtcacgt ccatccgacc gcccttctgc cgcgtcggga
    10981 cgacgccggt tgcgagcaca ccaaccggct ctgtccgttc gctgtcggat ctctcccggc
    11041 tgtcgacggg tgggggcggg cggcgccggt accgacggcg cactgacagt cgcctggcag
    11101 cgtgccggca cacaatcggc gcgttcggcc ggccgaaagg agaaacagtg cgacgaaacc
    11161 tccgaccgag agtcccgttc cgggtgatga cgatggctgc agctgcgctg ctcgccgtcg
    11221 tcgggctcgc cgtcgcgccg ccttcggcgt cggcggcgcc gccaccgatg ccgctcgtag
    11281 cgccgccgca gctgcccgac aacgcacggc cggtgtgcgg tcccgtgctg cccggctacg
    11341 tgcactgcga cgcgttcgta cgcaccgaca gtgcagggtc cgatcccacc gacccgcaag
    11401 aaccggcggc cggggaaccg gtacccagcg cgtaccgacc ggcggacctg caggacgcct
    11461 acggcctccc gtcggccacg gccggcggcg ggcagaccgt cgcggtcgtc gacgcatacg
    11521 acgatcccaa ggcggagtcg gatctggcgg tctaccgggc agccttcggg ctgccgccgt
    11581 gcacgaccgc caacggctgc ttccacaagg tcaaccagcg tggtgagacg aagaactacc
    11641 ccgcgcccga caggcactgg ggaatggaga tctcgctcga ccttgacatg gtctcggcga
    11701 tctgcccccg gtgccacata gtgttgtggg aggcggatca agcctcgcag gaggatctgg
    11761 cggctgccgc ccacctggcc ggttgcgact gcacctcgcc ggccggcacc aactacggcg
    11821 cgcggtacgt gtccaacagc tacggcggtc ccgaggcggg cttcagcgcc agtgtcgacg
    11881 actcgtacag atcggacaag gggacggtct acacggtgtc gtccggcgac agcggttacg
    11941 gggtggagta tccggcgtcg tcgaagtggg tgacggccgt gggcgggacc tcgttactgc
    12001 ccgcggacaa cgcccgcggc tgggacgaga tcgcctggct ctacggcggt tccgggtgct
    12061 cgacatacgt ggcgaagccg gcgtggcagc acgacggcgg gtgcagtggc cgcagtgtcg
    12121 cagacgtcgc cgcagtcgcc gatcccacta ccggggtcga catgtacgac agctacgaga
    12181 cggttgacta caacggtcca tggctggtca acggtggtac cagcgccgcg tcaccaatca
    12241 tcgccggggt gtacgcgctc ggtgcgaagg tgttgcccgg cacgatccca tcgacctacc
    12301 cgtacgcgaa gttcacccag ctcaacgaca tcgtcggcgg taccaacagc ttcgagaact
    12361 gctctcccga gtatctgtgc aacgccgggc cgggatacga cggcccgacc gggtacggca
    12421 cgccccacgg cgtggccgcg ttccaggagt gatgggtggt gcgcaccggg accgccggtg
    12481 cgcaccagcg ctcagcccgc gacgaccggg ccgacgatgt tcaccgacgg caatgttgcg
    12541 agctggtcgt agacggtctg gaacacgccc gggtcgttca tgtagtcgat gatctgctgg
    12601 tagttcatgc ccacggtgtt agcgacgacg ccggtcagga gggtgtaggc cacctgcgcc
    12661 tcgtcctggt ccagcaccgg ttggatgccg gcgccgccgg tcatcccggc gaacatgaac
    12721 tcgaggtcgt cgatgttctc ctgggtcatc gtggcgccgg agtcagggtt ggccaggacg
    12781 gtggcgacca gggtgcggta cttgtcgtag tactccttgg cgtatccgat cgcgacgccc
    12841 tcggcctcct ttccaccgag ccggtcgatg acggtctgct ggttgagata gatcgcgccg
    12901 atgagcaggt tgcccagcgg gctctgggcg agaaactggt ccctggcctg tgaggtcagg
    12961 tcgttgtcgt cagccagcgg caggtcgtag tagtggccga cggtggcgag cagctcgcag
    13021 ttcgacgtgg gcggctcggg ctcctgaacg aatgttcgcc cgttgccgcc ggcgagaacg
    13081 agggcgccgg agtcgccggg taggcagaac gcctgggacc agatctggtc ggtgagagtg
    13141 acgtacttga agccgtagtc gatcttcacg atggctgcga gcgcggtcac catgctcgag
    13201 gtgtaaccgg acgcgtggcc caccttctcg atgtgcgaga acagttgcgg tgccgcgatg
    13261 cagctgtgct cgtcgtcggc gaccgacagt tcgacgtgca gcgcgtcgac gatgtgatcc
    13321 atccgggaga tgaacgagtt gacgtgtcgt tgtagggggt cggtgtcgct ggcggtgatc
    13381 atgccgatag ccggatgggt ggcggagatc ggcgccatca ggccgtcggc gacgccgagg
    13441 tcggcggtga cgccggagtt gagtaccccg atcgccgcgt cgacggtggc ggtcgtgccc
    13501 agctcgctga accggcgtac ggtgccgatc gcgtcgttac tgcccccacc gtcctgcctg
    13561 gccggctggt agatcgcctc gccgaaggcc ggctgatcga cccgggcgag caccgagttc
    13621 gatgacagga agcagatcct gccgtcgttg ttgtcgaggt cccggacgaa gcagcccaac
    13681 gtgccggaca gcgagccggt cgcgttggag atccccgcac cctggaccgg gtcggtgaac
    13741 ttcttccgga tcgggtcgtt caccgcgttc ggtttcgccg ctccggcatc cgggccgggc
    13801 cgataggacg cgttcgccac cgcgggcagg ccgggatgcc gcagcgggcg gacctcgacc
    13861 acgtcgacgc cccaccggcg cccgtcgacc tcgatcgtcg ccggcaccat gcggtgcagc
    13921 gggatctgcc cctccgccag cttcttgcgc accatggcga tcacgacagg ttcgtcgacg
    13981 tagtcgccgg cgcggtgccg catcccgatc gccgcaccgg tgaagtgcgg gtcgtcccgg
    14041 aagacccgga acaacttgcg ctgcgcgcgg atcagcgacg cctgtacgtc ggcgtcgaac
    14101 accatcggtt ccagtttcat cggatcctcc tggccgggct cggcacgcgg tcgggtccag
    14161 ccggtaggcg ccgcagcccg ccgatccaca gctgcgcagc ggaatcggag ttcgggtcga
    14221 agtgggtact gatggtggcg acagccaacg cgaccgtggc ggtcaccgtg gtggcctggt
    14281 cgcctctggc gagcgcggtg atcgcgccgc gcagcgccgg gtcgtcggcc ggatcggcct
    14341 cgatcagtgc gtttgcgccg gcctgaacga gtttcgaccg ggcgctaccg acctttcccc
    14401 acgcggtctg caaccgtgcc atggtggccc gggacacggc agagcccgac tccgcgaacg
    14461 acgggaacgg gatcgggtac accgcgccgg ctgctgcgat tcgtagcacc atctcgcact
    14521 gttcggcgga cagagcgccg gccgacgcgt cggccggcgc tccgcccgtg ccgaccgcca
    14581 cggcggtcgt catcgcggcg gtggcagcca acagggcacg acgggtgagc cggcgtgccg
    14641 acggacctgc tcgttctggt gtggctgagc tcatcgagac catctcccgc aaccagtcct
    14701 ggtgggtcca gtcatggatg ccactgccgg ctttcggtcc gctgtcagct cactccgaat
    14761 ccggtaccag cggacgtttc ggctggtggg agtcgggtcg gatgccggcg ggacgaggcc
    14821 gctcctagct gaaggcggtg agggtcaggt gcagggcggt cggcgcgccg tcctcgatgt
    14881 acgaggcgaa gccgccgacg tcgtcgaacg ggaacccgta cgccctgccg tcggtcatgt
    14941 gcgcgtgcat gatccgcgcg tagtggttgg tcgggtcggt ggcgtagaag ccggccgggt
    15001 cgtcggtcgg ctggctggcc gaggcgagca gggtggagcg gttgaagccg gcgccgagcg
    15061 ccgcggccac cgggccggtc aacccgtcgt tcggtgcggc gagcgcgccg gcgcagaaga
    15121 acacgtccga ggtggtcggc ttcgagatgg gggcgaccgc gccgtcgaag gtgaacacac
    15181 cgccggtgac ccggccggtc cggtcggcgc cgccggtgtg cacggtgagc gtctcgccgg
    15241 cgtacttcga ccagacgtcg tcgaggtagc cgtcgaagta gtcggcggcg aaccggccga
    15301 cctcgatccc gtgcccgggc gcgatgacgc gcaggtcgtc gagcaccagc gagccgaacc
    15361 cggcctgggc ggccacctcg gcgaagatcc ttcctcgtcc gccggcttcc agcgtcccgg
    15421 tggtctggtc ggcggcgccg accaggtgca ccgacgacgg cacgccgaac atgtcgacct
    15481 gggtgttgtt gcagtgcatc ccggagccgt cgtaggtgaa ctcgaagaag tcgtgcagca
    15541 ccgggtagtt cgggtccgac tcgacccagc cggccgggta cgccagcgcc gggttgccgt
    15601 tgccgtccgg caccgccttg aacctcagcg ggtcgccgag cgcgaagtag atccggccgg
    15661 acatgtgcgg cagcgcgatc gtcgtgtcgc cgctgccggc gagcgggatc gagtagtcgg
    15721 tgtagccgtc ggatccgttg tcggacagcg acaccgggat caggttgccg cccgcgtcgg
    15781 cgtgcgcctg ggcgccggtg gcgaggtcgg tgcccaccac gtacagccgg acggcgtcgt
    15841 tgccggccgc gccggagtcg ttggtgacgg tgaccgccag ggtgccgtcc gcgaacggtc
    15901 cccgggtacc ggcggcagcc accgacggcg cgccgaacgc ggcgaccagc ggcgctccga
    15961 tcgcgccgag cgcgaggccg cgcagcagcg atcggcgggg tacgggggtg tcggacatgc
    16021 ccgctccttt cgcttgtctg tccacagggg acttgtcagg ttgctgtgcc accactggat
    16081 tcgcggacca ccagccgggt cggcagcagg accgagcggg acggttcggt ggccggtgcg
    16141 gcggcgagct cggccagtac ggccgccgcg gtggtgccga agcgccggta gtcctgggcg
    16201 atcgtggtca ggccgggccg gaccatcgcc gccgcgtcga tgtcgtcgaa gccgaccacc
    16261 gcgacgtcgc ccggaagcgt acggccggcg tcggccgcgg cccgcatcgc cgcgatcgcc
    16321 atcgcgtcgc cggcgacgaa caccgcggtc ggcggggtcg gcaggtcgag cagccggcgc
    16381 atgccggcgg caccggaggc ggcgaagaag tcgccggtca cctcgtaccc gggccgccgg
    16441 cgcagccgcc gccgggcgag ctcggcccgg aagccggcga gccgttccgc cgccggccac
    16501 aggtccagcg ggccggtgat ggtggcgatc cgccggtgcc ccaacgcatg caggtgcgcc
    16561 accgcgtcgg ccgcggcggt gcggttgtcc gatccgacgc tcgcggtacg cggaccgtcg
    16621 agcgcgaggt cgagcccgac gcacgggacc ggcgttgcca gcagcgcccg tacctgcggg
    16681 gtgtgctggt cgacgcccat catcacgatg ccgtccaggg tgtactgccg ggcgagccgg
    16741 acgtagccgt cctcgtcgtc gggcggcacg atcggcagga ggatcagccc ctggccgcgg
    16801 tcgctgagcg ccgccttgag cccgatcagc acctcctgca ggaacgggtg ctgtcgcccg
    16861 ccgctgcggt agccggtgtc ccacagcagc ccgatcagcc cggaccggcg gctggccagg
    16921 gtgcgcgcgg acgcgttggg gcggtagccg agttcggcgg cgagtgcgac gatgcgggcc
    16981 cgggtcgcgg cgctgacctc gggtcggccg ttgagcgcgc gcgacacggt cgcggccgag
    17041 acgccgctgc ggcgggcgag ctcgtcgatg tccacaggac gcactcccga cataaccgac
    17101 gtaagcgctt ccggtccagt aaagaaccct taccgaagcc ctgtcaaccc cggcccaccg
    17161 cgctcgtgga cgcaggttcg cgctccggcg ggcggggcgg ctacgcggac gcggctggcc
    17221 gcgtacctcg gcggtgccgg tcggctactc cggtcgcagg taccggcgga gcacgtcggc
    17281 ctccgcccgc agccggtcgg ccgcctcggc gcgcccgctc cgggcgtacc cggtcgccgc
    17341 gtccacccgc tcggccacct cggcggcgac gatggcgtgc aggtcgtccg ccgtcagctc
    17401 ccggcgcgcc gcctcggccg cgccgacgcc gaccaccgcg cccgccacgt gctcggcgtc
    17461 ggaggtcggc gagtccggtg ccggtaccgc ctcggcattg tcgatcgcgg ccagggccga
    17521 ccgcagcgcg gagacggcga cccggtcccg ggccttgagt gcggcggtca gatcgcggcg
    17581 cagggtggtt cgcatgggcc gcgacgctaa ccgcggctcc cgccggtggc aacgcttttc
    17641 cggccggcga cgaggccgca cggagccggt cggccggcgc tcagagcttg gcctggcacg
    17701 gttcgggccg gggcgcggcg atctcggggt ggatgtcgcg gtgacgcggc cgccgggccc
    17761 ggcgggacag caggtggccg gccagggccg cgaggaggcc ggcgagtccg gccgccgcga
    17821 aaccggccgc cggagcggag gcatcgatcg tccagccgac gaccggggcg ccgagcgcga
    17881 cgccggcgct catcgccgac gcctgcagcc cggtcgcctc gccgcgcacc ccggccgggg
    17941 ccagccggct caccgcgtcg gccacggtgg acagcgtcgg tgcggtgagc agaccggtac
    18001 cgacgacggc caggcacagc cagggccagc tgggggcgag cccggccagt acggtcgcga
    18061 cgccgagcag gccgagcagc agccaggtcg gcagtggccg gttcagcatg ccgtagcaga
    18121 gcccgccggt gaccgaggcg aggccacaga cggcgaccac gagggaggcc caggagacct
    18181 ggccggcctg gcgcagcgtg gccacgatgg cgaggtcgat gccgccgagc agcagggcga
    18241 tgccgaacgc cagcacgagt acggcgatca tcccggcccc gagccactcg cggcgcggcg
    18301 gccgcggtgc cgtaccggcg ggtgcctcgt cgggcgagcg cagcggcggg tccagggcgg
    18361 cgagcgcggc gccgccgacc acgatggcgc cgccgattcc ccacgccatc gtggcggggg
    18421 acagcgtcgc cgcggcgagg atcaccgcgg ccgggcccac caggtacgac agctcgccct
    18481 ggaccgactc cagcgcgaac gccggccggc gctgcccgcc ggtgctcagc gcggcgatcg
    18541 cctgccgggt caccgcctgc gccgggacca tcagcaggcc ggcgacgaac gcggcgccca
    18601 gcagcaccgg gtaccgcagg gccggtaagg ccagccagaa cccggcctgc gtgacgacgg
    18661 tggccagcag cgcggtacgc aggccgcgcc ggtcgatgag ccggccgagc agcggcccgc
    18721 ccagcgccag gccggcggtg agggaggccg ggacggcgcc ggcggccgcg tagccgaggt
    18781 gcaggccgag caccacgtac agggtcaggg ccatgccggc cgccgtgatc gcggtgcggg
    18841 cgagcagcga gacggcgagc agcggtgcca ttcccggcac cccgagcacc tgtcggtatc
    18901 cggtcacctc cgtgacgcta gatcagaccc gaagccatag gaactggcga tctgattagg
    18961 cgtgctataa ctgattgtta tggcacgaga gttggagacc gcactgctgc gctcgttcgt
    19021 caccgcggtg cgggccggca gcatcagccg cgccgcgacc cagctcgggc agacccagcc
    19081 cggaatcagc cagcagctgc gcaagctcga acgcgccgtc ggccatccgc tgctgcaccg
    19141 gtcgtcggcg ggcgtcgcgc cgacgcgcgc cggcgaggaa ctcctgccgt acgcggagcg
    19201 catcctcgcg ctcgccaccc aggcgctcgc cgaaaccggg cacgcgctca gcggccactg
    19261 cggcatcggg ctgctggagg acctggccgc ctcgcacctg ccgcaggcgc tcgccgacct
    19321 cgcccggctg cacccggacg cgacgctgga ggtgctcagc ctgtccagcg cgacgatgcg
    19381 cgaggcgtac gacgcgggcc gggtccagct cgtcctggac gagctgccgt acctgccggg
    19441 cccgccgcgg tggacggtgc gccgccctct cgcctgggcg gtcggccacg gcgtcgagct
    19501 gaccgcggat ccgctgccgg tcgtgctgtt ctccggcacc tgcacctggc gcagctcggt
    19561 actggaggcg ttgtcccagg tggaccggcg ctggcggatc gcgttcgaga gcgacagcct
    19621 ggccggcgtg ctggccgcgc tgcgggccgg gctgggcgtc tcggcgctgc tgccggccaa
    19681 cctcgagccg ggcatggtct gccacgacca ggcagccctg ccggcgctgc ccgacgtcga
    19741 gctgggcctg acccggcacc cgcgcaccga cggcgatccg ctgatcgacg cggtggcggc
    19801 cgtcctgcgc cggatggtct gagccgggtg agcccggatt ccggacggcc tggcccgggg
    19861 tgagcccagg ttccggccgg tccgggcggc gggacggtac gagcccggtg gcccggttcc
    19921 gagggtcttg gcggcaggac ggtctggtgc ggacgctgtg cgcgccaccg tccgagtgct
    19981 cggcgccgca gggcgggtct accgggcggc gagcagggtg tggatcgcgt cgacggcggt
    20041 ggtcagcccg tcctcggcgc gcatcgccgc gccgacggtc gcggcccggc cccggtagcg
    20101 tgccgtacga gcggcggcga tcgcgcgggc cagcccggcg gcggtgatcc ggcggatgcc
    20161 gctcgcggcg ggtgcggtac ccagtcgctg cagttgccgc gcccagaaga actggtcggc
    20221 ggcgaacggc aggaccaccg agggcacccc ggcccgcgcc gccgtgtgcg tggtgccgga
    20281 gccgccgtgg tgcaccacca ccgcggtacg gggaaacagc cagtcgtgcg ggacgtcccc
    20341 gacgacgcag aagttcgccg gcagctccag ggcatcggcg ccgctccagc ccggcgcgaa
    20401 gaccacccgc tcgccggccg cggcggtgac cacgacgtcg agcagggcac gctggtcgaa
    20461 cccggccatg ctgccgaacc cgacgtagat cggtgcgtcg ccggcggcga ggaactcggc
    20521 cagcgccgcc ggtggcgacc actcgtcggc gggccggaac cactgcccgc acagccgggc
    20581 gtcggccggc cagtccgccg gccgcggcag caacgtcggc gagatcccgt acagcatggg
    20641 atgaccggcc cacggcttgc gtcccggcgg caggccgacg gacgcccgcg cggcgttggt
    20701 ggcgccgcga aacgagcgcc acagcacggc ctcgaccagg cggtaactgg cccggttgag
    20761 ccggccgggc agccgccgcg gtggcaggaa cggcgacggg aacgcggcgg tggcggtgag
    20821 cgggatcatc ccggcgccga gcgctggcag gtggagcttc tccgcggcgg agaaccccac
    20881 gtacgcggcg aggccggcga cgatcagcgc gtcgcagccg gccgccgtgt cgagcacctg
    20941 gtccagccag gcgc
//
