LOCUS       NZ_AP023354            21089 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Actinocatenispora sera strain NBRC 101916 chromosome.
ACCESSION   NZ_AP023354
VERSION     NZ_AP023354.1
KEYWORDS    RefSeq.
SOURCE      Actinocatenispora sera
  ORGANISM  Actinocatenispora sera
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinocatenispora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Actinocatenispora sera NBRC 101916
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7044238)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 251x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018324685.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 04:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,585
            CDSs (total)                      :: 6,501
            Genes (coding)                    :: 6,404
            CDSs (with protein)               :: 6,404
            Genes (RNA)                       :: 84
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 26 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 1 of 97
            Pseudo Genes (multiple problems)  :: 10 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:48:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 840724
            Orig. end                         :: 861813
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..21089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="4"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21089
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11089](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11089
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(2..16)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            281..2086
                     /locus_tag="Asera_RS03840"
                     /old_locus_tag="Asera_07800"
     CDS             281..2086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620829.1"
                     /locus_tag="Asera_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07800"
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_051803050.1"
                     /transl_table=11
                     /translation="MRIEDYALIGDLQTAALVGRNGSVDWLCLPRFDSAACFTALLGEP
                     THGRWLIGPVDPVTRISRRYRDGTLILETDLETADGAVRLIDFMPPREPGARPQLTRIV
                     QGLRGRVRLQVELVVRFEYGSVVPWVQRVPDGVVAQAGPDALHLATSVPLHGHELTTVG
                     EFELAAGGTERFMLTWFPPYEPPGLVEDAYSALARTERWWLDWSGRCGYTGAYADEVLR
                     SLIVLKALTDRQTGAVVAAPTTSLPEDLGGERNWDYRYTWLRDSVLALNALLAGGYTGE
                     ARAFADCVFRATAGHPEQMQIMYGIAGERRLAEYELDHLPGYEGSRPVRVGNAAAGQFQ
                     LDVYGEVLGVAAVVAGHVGRYPDRQWRQQRKLLDYLDGVWQQPDDGMWESRGPRRHYTQ
                     SKLMAWVAFDRAVAMANRFGLDGPVEKWAATRDAIRAEILDRAWDPRRETFTQYYGSTA
                     LDAGALMIPLVGLLPGGDPRVTSTIDVVRAELGRDGLLSRYSTDDTDDGLPGTEGQFLA
                     CSFWLVDALAWNGRRDEARELFERLLGLANDVGLFAEEYDVRHGRQVGNFPQAFTHLAL
                     INAARVLSPDQPHPFEQAPPAPRSS"
     gene            complement(2184..7661)
                     /locus_tag="Asera_RS03845"
                     /old_locus_tag="Asera_07810"
     CDS             complement(2184..7661)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286815.1"
                     /locus_tag="Asera_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07810"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_030449671.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.7e-08,
                     bitscore: 32.1, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.2e-09, bitscore:
                     36.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSRVAIVNRGESARRLIHAARELSAQTGHRIETIALYTDVDRAS
                     TFVREADHAYDLGPASARPYLDLKVLERALRETRADAAWVGWGFVAEDPAFAELCEQVG
                     VTFVGPSAEAMRTLGDKIGAKLLAEEVGVPVAPWSRGAVETLDAALTAAAEIGYPLMLK
                     ATAGGGGRGIRVVTSGAELTDAYERTSQEAARAFGSGVVFLERLVTGARHVEVQVIADG
                     EGTAWALGVRDCSIQRRNQKIIEESASPVLPADKVTELKASAERLAVAVGYRGAATVEF
                     LYHPGTEVLAFLEVNTRLQVEHPITESTTGFDLVKAQLHVASGGRLVGNPPVERGHAIE
                     ARLNAEDPDRDFAPAPGRIARLDLPAGPGIRVDTGVSEGDVIPADFDSMIAKIIAYGRD
                     RDEALGRLRRAMRQTTVVIEGGATNKSFVLDLLDAPEVIDGSADTGWIDRVRGEGRLVS
                     HRHSAVALAAAGIEVYEDEERVEQQRLLSTAFGGRPQVQHDSGRPLDLKLRNVGYRVRV
                     ARVGAHRFRVGIEAGGELRTADVELDRFDRYSGQIVVNGARYQLLTDTHGPVHLVEVDG
                     VTHRVSRDEGGVVRSPVPALVVATPLAVGDEVEAGAPVLVLESMKMETVLQAPFRARLK
                     ECTVSVGSQVETGAPLLRLEPLADDDAEAAVEQPAAPVELDLPNGPTTVPAADRVRRGQ
                     EDLRSLLLGFDVDPHDERRVLDDYLAARRELVASGHRPLSGELALVEVFADLAELSRNR
                     PTDEDGTDTHVHSPREYLHAYLQSLDVERAGLPDSFQAKLQRALAHYGVTELTRSPELE
                     AAVFRIFLAQQRSATDAGVVTALLRAWLQEPPPDGTLREPTGLALERLVSATQLRFPVV
                     SDLARGVVFGWFGQPLLRRTRAKVYAKVRAHLRYLDAHPDAPDRADRIAEMVRTTEPLV
                     RLLGQRLPRAEKDNTVMLEVLTRRYYGNKGLTNVRASRVPLGTFVVAERAGSYLVSAAV
                     RFERLGDALRGLEQLATGDTTIDADVYLSWDNLPGDADEMAAALSEVVRANPLPYQVRR
                     LTVTLAGGRAGAMHHHFTFRASPTGMTEDRLIRGLHPYIAQRMQLERLNRYDLTRLPSS
                     DEEVYLFQCVAADNPSDDRLVAFAQVRDLSPLREQDGRLVALPTAEDVVATCVDSIRRA
                     QSRRSPRNRFNTNRIVLYVWPPSELTDDELDIIAKRVLPATAGAGLEEILFIGRRRDPQ
                     TGALNKIAMRICFDANGGVQVVFGEPSDEPLEPLDDYRLKALRARSRNSVYPYEVTELL
                     GEFVEHDLDDAHALVPVHRPKGRNTAGIVAGVATTVTRRHPEGVTRVVLLGDPTKSLGA
                     LSEPECRRVIAALDLAERMRVPLEWYTLSSGARIAMRSGTENMDWVAAALKRIVEFTQA
                     GGEINVVVAGINVGAQPYWNAEATMLMHTKGILVMTPDSAMVLTGKQALDFSGGVSADD
                     NFGIGGYDRVMGPNGQAQYWAPNLAAAHDVLLAHYDHTYVVPGEAAPRRAETTDPADRD
                     VSDFPHSVAGSDFRTVGEIFSAANPDRKKPFDIRTVMRALSDQDHPTLERWASMADAET
                     VVVQDAHLGGYPVCLLGIESRSVPRRGFPPTDGPDAYTAGTLFPRSSKKAARAINAASG
                     NRPLVVLANLSGFDGSPESMRKLQLEYGAEIGRAIVNFDGPIVFCVISRYHGGAFVVFS
                     KALNPNMTVLALEGSYASVLGGAPAAAVVFAADVKSRVAADPRVRELEARATAASGAER
                     AVLTAELDELRTTVRAEKIGEVAAEFDRIHSIQRAVEVGSVDAVIRTAELRPRIIATIE
                     AGLRSSTREA"
     misc_feature    complement(7875..7888)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.65"
                     /tool="antismash"
     gene            complement(7941..8855)
                     /locus_tag="Asera_RS03850"
                     /old_locus_tag="Asera_07820"
     CDS             complement(7941..8855)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015338.4"
                     /locus_tag="Asera_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07820"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_030449670.1"
                     /transl_table=11
                     /translation="MIITLATVNAWQLYDEQAAQPERWRRVEELVAGLNADVVAVQELI
                     ADGADEPARQAGADAALRRLAERTGLYCEVDGRAAAAAGGGRYHAGLLWRADRASVRPG
                     SLVRLGRASHGLWHGMVTCVLTIDGTPLRVGSVHLSPHSPPWRAADAYQVLTAMHPDTL
                     PGFVGGDWNSIGASRIETGDGWHHYDRSPYPAPVWHPAHGYQLGGDGQVDRGAAEVLEN
                     AGGMRDCAVLFGAPWQPTTGYHPIDPQPPRRIDRWYATHRVPAAAIAGYAVADPGRVGT
                     DTDHRPVLVTVDTGALPGAAPAG"
     gene            complement(8901..9167)
                     /locus_tag="Asera_RS03855"
                     /old_locus_tag="Asera_07830"
     CDS             complement(8901..9167)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="Asera_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07830"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_244843725.1"
                     /transl_table=11
                     /translation="MLADPTRLRLLCLLRDAELDVGSLAAATGSARPAVSQHLAKLRLA
                     GLVRTRRDGRRALYRARGGHVRRLVDEVLAAAQHHLTGAPDHD"
     gene            9178..9717
                     /locus_tag="Asera_RS03860"
                     /old_locus_tag="Asera_07840"
     CDS             9178..9717
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01297.1"
                     /locus_tag="Asera_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07840"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_084132844.1"
                     /transl_table=11
                     /translation="MAAVSISSSSGSCCRISVGRRIGSAALVADGLHARTDGFTSLTVL
                     LGAGGVAIGWSWADPIVGLAITVAIAFVLKDAAREIYRRLMDAVDPDLVDAAETALAAT
                     PGVRVVGALRLRWIGHRLHAETDLTVDASLSVLDAHAIAVDAEHALLHAVPRLSEVTVH
                     TDPATDNAHEPLAHHR"
     misc_feature    complement(9853..9868)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.91"
                     /tool="antismash"
     gene            10001..11089
                     /locus_tag="Asera_RS03865"
                     /old_locus_tag="Asera_07850"
     CDS             10001..11089
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_07850"
                     /product="hypothetical protein"
                     /protein_id="WP_212804507.1"
                     /sec_met_domain="indole_PTase (E-value: 2.1e-34, bitscore:
                     117.7, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLSPFTQRPILGRAMGEYLIDIWTTACETLGLAAEQWQPPTQEL
                     QRLLPDWADDQIQAAPRETSYVADDGFPAELSANWSGAHPELRMLFDCLSDVPHRAGVT
                     DPRSSLWSGSSLFTSISRLFRQPVAAPLWHSMAWRAPNPPAHKVYFGLYGWPLARRGAV
                     VDRAMQLVGLGRAWEHARHRIENGARYGSREIEFVGLDIGDSAVARVKIYYRHQGVDVA
                     EMNRVASVALHHDEGRALAAYRMLTGGRDDAGDAPLTCLAFRSGYQQAVEATTYLRMPS
                     LTTCEQESVERTSALMESEGVPAQRFVALTEAFSPRRSDGGRGVLELVSHRARRSGDVT
                     TYFRFPTFSQPAALPVASAQRA"
     gene            11110..11769
                     /locus_tag="Asera_RS03870"
                     /old_locus_tag="Asera_07860"
     CDS             11110..11769
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_07860"
                     /product="hypothetical protein"
                     /protein_id="WP_030449667.1"
                     /transl_table=11
                     /translation="MSQPDRSNVDRVAEYNNQRQEQYRASRLCQLLLDDTVAEETKKAT
                     LPLLQPWSNAFQRMITARVQAEASRIQTDQDPELLALAIEHWQEEVGHNDILKRSRGGT
                     DQVIWDPVIEAGAAWFIEQFRTLPGMQRAMLAHLVLEAGSLVFSQAGVRAFPHDEYFAK
                     HDEDDVEHLEMGYRLLRSRSDWSVDEMVTIMDRGWQIITLVSDRIAECAVRDTAAA"
     gene            11766..12581
                     /locus_tag="Asera_RS03875"
                     /old_locus_tag="Asera_07870"
     CDS             11766..12581
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_07870"
                     /product="DNA polymerase"
                     /protein_id="WP_030449666.1"
                     /transl_table=11
                     /translation="MIDTAQDRARGVALGAARVWQAAFGERLTAAYLLGSLAHGGYSPS
                     ASDIDLGIVLSEVRPGDRQLADDCATSVREQAGLYGKVSAFWASLPALRDGREDGRFPA
                     LDRLDLADHGQLLLGIAVREAVARPDRTELLLSSSRFALEILAVPEVVAEFHQPQRLLT
                     DVVLFTKAVLFPVRFLHATAEDGGAVGNDVALDWYLAQPDPVSAPLVRLAASIRAGAAL
                     DPDKALPLLAGLRPLYRCYIDDRVERLRLAGAPDDLISGFATWRDRLRD"
     gene            complement(12591..13166)
                     /locus_tag="Asera_RS03880"
                     /old_locus_tag="Asera_07880"
     CDS             complement(12591..13166)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082429.1"
                     /locus_tag="Asera_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07880"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_030449665.1"
                     /transl_table=11
                     /translation="MEPQSVKIVVAGGFGTGKTTLVGSVSEIPPLTTEELLTEASKPVD
                     DLAGVESKTNTTVALDFGRRTINEEVVLYLFGTPGQDRFWFMWDELALGALGALVLVDP
                     RPARLNSSFAAIDYFEARRIPYVVGVNMFHGVCAYEDHEIRSALKLGTEVPFVRLDARD
                     RESVRRALIRLTEHALARLPVVGEPAAR"
     gene            complement(13185..13559)
                     /locus_tag="Asera_RS03885"
                     /old_locus_tag="Asera_07890"
     CDS             complement(13185..13559)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017170.4"
                     /locus_tag="Asera_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07890"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_030449664.1"
                     /transl_table=11
                     /translation="MAGQNDEWVDDDAGGLVPLYAVAGRRATADISSDLNLGSMVRATT
                     ADLDPTYFEPHQVQILRLCQRWLTVAEISAIGKVPLTITKRQLADLIDRGVLALSSGTT
                     SSAAPTRDRLVQVLDGLRAM"
     gene            complement(13564..13968)
                     /locus_tag="Asera_RS03890"
                     /old_locus_tag="Asera_07900"
     CDS             complement(13564..13968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020519295.1"
                     /locus_tag="Asera_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07900"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_211255806.1"
                     /transl_table=11
                     /translation="MNVDWALDDLVDGLNALCAVAVSTDGMLIQRSRRISKDSADSLAA
                     RASSLASIARGISRQFGSGPMQQTIVEMKDAYLVITAAGPNACLAVLADVNADLGQVGY
                     EMNRLVKRVGVHLGSQPRDTTAALNGGLEG"
     misc_feature    complement(13934..13949)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.75"
                     /tool="antismash"
     gene            complement(14025..16529)
                     /locus_tag="Asera_RS03895"
                     /old_locus_tag="Asera_07910"
     CDS             complement(14025..16529)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.4"
                     /locus_tag="Asera_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07910"
                     /product="ATP-binding protein"
                     /protein_id="WP_084132840.1"
                     /transl_table=11
                     /translation="MTSQQTHQRQAGRDRRPRRQRSIRQGVVRVALVPSVALIALWLVG
                     ASYLGYTGVYARQVASSVRQVSIPAVNGLASLQKERQLSMAELANSAGTPAGTRSLNAQ
                     RATSDEGLASMQNAAKAALGSAPASIKDQMATVTGYLHELPKVRAQIDARTISPQNVYA
                     FYNKILDASIQLFNTQARIIPDATASQGGFAATDLFRVSDLMSRAGSQAAGAFAAKKFS
                     TNDYLTYVQLVGAYRSQLSNVEADLLPDVRAGVRRMMRSDEWSRLSAAEDAILADGAWQ
                     GGVPTGLPVDSAAWGKLTDQVSNDLIELAKSQADEVSAQGLASGNQNLGWAIGGSVAAA
                     AVVALAILWALRRSSVLVGRTLIPRIRQLGEDANLIVRTRFPAIRERLAAGERVNVREE
                     LGQINSAADEEAEQGQDEIDNVRKTLNDAVVLAADAVVSEGQARAGVLRVFLGIAYRNQ
                     RPLQQASRALDAEERAEEDPARLEKWFRVHHRVNQVRGVNESLIILGGGKPGRKFQTPI
                     PLLQVMQAAKAQAEDYDRVKLETAPEVRVRGDAVNGTIHLLTQLLNNAIGFSSTESDVR
                     VRGVYVDRGIAIEVEDRGIGMAPEDLDQANAMLKQAPEFNVNALGDGSQLGFWVVAQLA
                     KQLGITVTLTTSPYGGVLAVVLIPKAQLDNAADRSGDISRMAESVDVPRDVEQTMQMPA
                     FVGAPPAPRRPGLSTNGAAHRLDSGSAHRPAPTARPVSPAPRIQPGTGHASLGARDIGV
                     EPPARVTAIRQQPQVPERDARPGRPPLPERQPQQHIAPQLREDLEHPGTPEQAIDMGDP
                     ELIRNRLARFQQGSNAGRAEDN"
     misc_feature    complement(16546..16562)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.02"
                     /tool="antismash"
     misc_feature    16550..16562
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     tRNA            17663..17735
                     /anticodon=(pos:858420..858422,aa:Lys,seq:ttt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Asera_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Asera_t00100"
                     /product="tRNA-Lys"
     gene            17663..17735
                     /locus_tag="Asera_RS03900"
                     /old_locus_tag="Asera_t00100"
     misc_feature    complement(17830..17846)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.41"
                     /tool="antismash"
     misc_feature    17986..18002
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    18663..18683
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.55"
                     /tool="antismash"
     gene            19308..19511
                     /locus_tag="Asera_RS03910"
                     /old_locus_tag="Asera_07930"
     CDS             19308..19511
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283833.1"
                     /locus_tag="Asera_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07930"
                     /product="cold-shock protein"
                     /protein_id="WP_030449661.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNADKGFGFISPDNSGEDLFVHFSSIQSSGFRSLDEN
                     ARVQFEIETTGRGPQAMNVSTL"
     gene            19633..20712
                     /locus_tag="Asera_RS03915"
                     /old_locus_tag="Asera_07940"
     CDS             19633..20712
                     /EC_number="1.14.19.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020513781.1"
                     /locus_tag="Asera_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_07940"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_030449660.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 2.1e-13,
                     bitscore: 48.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLRSTQVDQRRAAQADQFAGSYKAVAQVVRELGLLRRARWFYGL
                     LFGGLCLALAGAVTGFVLLGDSWWQLLIAATLGVICTQFAFLAHEASHRQIFSGGPAND
                     RAGRLLGTLLVGISYSWWMGKHTRHHANPNRVGKDPDIEIDTISFLAEDAATRRGLLAA
                     LTRRQGYAFFPLLMLEGINLHVSSIRFLAGRRRITGRWTELGLIAAHLALIATPAFVFL
                     SPRIAGAFCGVQLAVFGVYMGASFAPNHKGMPIVGADEKLDFFTKQVRTSRNIRGRFWA
                     SALMGGLNYQVEHHLFPSMPRPHLAKARSVVRDYCHSRGIPYTETSLPRSYAIVIAYLN
                     EVGLAARDPFECPMLALRR"
     misc_feature    20758..20773
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.86"
                     /tool="antismash"
ORIGIN
        1 gtggccgacg tgctcggctg gctggacggt gagccggttc gcgtcctcgg ctgagccggt
       61 tcggtccgcg gcgccgccgc agaccggtcc ggaggtgcgg caccggatca cgccgtcgcc
      121 gcccgctcgg tcccggctct tgccggggcg gccggctcgg caccgctgct cgctgctcgc
      181 cggtgcggct cggcatcgct gcttgccggt gcggctcggt accggcgttt gccggtcggt
      241 gcggccggcc gccacgtagc gtggtacggg ggtgtgccgc atgcggatcg aggactacgc
      301 gctgatcggt gacctgcaga cggcagcgct ggtggggcgc aacggatcgg tggactggct
      361 gtgcctgccg cggttcgact cggcggcctg cttcaccgcg ctgctcggcg agccgacgca
      421 cggccggtgg ctgatcggcc cggtcgaccc ggtcacccgg atctcccggc ggtaccggga
      481 cggcacgctg atcctggaga ccgacctgga gacggcggac ggcgcggtgc ggctgatcga
      541 cttcatgccg ccgcgcgagc ccggcgcccg gccccagctg acccggatcg tgcagggcct
      601 gcgtggccgg gtacggctgc aggtcgagct ggtggtgcgg ttcgagtacg ggtcggtcgt
      661 gccgtgggtg cagcgggtac cggacggggt ggtcgcgcag gccgggccgg acgcgctgca
      721 cctcgccacc tcggtaccgc tgcacgggca cgagctgacc acggtcggcg agttcgagct
      781 cgcggcgggc ggcacggagc ggttcatgct gacctggttc ccgccgtacg agccgcccgg
      841 gctggtggag gacgcgtact cggcgctggc ccggaccgaa cggtggtggc tggactggtc
      901 cggccggtgc ggctacaccg gtgcgtacgc cgacgaggtg ttgcggtccc tgatcgtgct
      961 gaaggcgttg accgaccggc agaccggtgc cgtcgtggcg gcgccgacca cctcgctgcc
     1021 ggaggacctc ggcggcgagc gcaactggga ctaccgctac acctggctgc gcgactccgt
     1081 gctggcgctc aacgcgctcc tcgccggcgg gtacaccggc gaggcgcggg ccttcgccga
     1141 ctgcgtcttc cgcgccaccg cggggcatcc ggagcagatg cagatcatgt acgggatcgc
     1201 cggcgagcgg cggctcgccg agtacgagct ggaccacctg ccgggatacg agggctcccg
     1261 gccggtacgg gtcggcaacg cggcggccgg ccagttccag ctggacgtgt acggcgaggt
     1321 gctcggcgtc gccgccgtgg tcgccggcca cgtgggccgg tacccggacc ggcagtggcg
     1381 gcagcagcgc aagctgctgg actacctcga cggcgtgtgg caacagccgg acgacgggat
     1441 gtgggagtcg cgcggcccgc gccggcacta cacccagtcg aagctgatgg cctgggtcgc
     1501 gttcgaccgg gcggtcgcga tggcgaaccg gttcgggctg gacggcccgg tcgagaagtg
     1561 ggcggcgacc cgggacgcga tccgggccga gatcctggac cgtgcctggg atccgcgccg
     1621 cgagacgttc acccagtact acgggtccac cgcgttggac gccggggcgc tgatgatccc
     1681 gctggtcggg ctgctgcccg gcggcgaccc gcgggtgacg tcgacgatcg acgtggtccg
     1741 cgccgagttg gggcgcgacg ggttgctgtc gcgctactcc accgatgaca ccgacgacgg
     1801 cctgcccggt accgaggggc agttcctggc ctgctcgttc tggctggtgg atgcgttggc
     1861 gtggaacgga aggcgggacg aggcgcggga gctgttcgag cggctgctgg ggctggccaa
     1921 cgacgtcggc ctcttcgccg aggagtacga cgtgcggcac ggccggcagg tcggcaactt
     1981 cccgcaggcg ttcacccacc tcgcgctgat caacgccgcc cgggtgctca gccccgacca
     2041 gccgcacccg ttcgagcagg caccgcccgc gccacggtcc agctaggacc gtccacatcg
     2101 gacggtcaag cacggccgaa cgcgaaggcc cggcaccggc ccgcgtgggc gggccgatgc
     2161 cgggcccggg cgacagatcc ggttcacgcc tcccgcgtcg aggagcgcag gccggcctcg
     2221 atggtggcga tgatccgcgg tcgaagctcc gccgtgcgga tcaccgcgtc gaccgagccg
     2281 acctcgaccg cgcgctggat gctgtggatc cggtcgaact cggcggccac ctcgccgatc
     2341 ttctccgccc gtaccgtggt gcgcagctcg tccagctcgg cggtcagcac cgcccgctcg
     2401 gcgccggacg ccgcggtcgc ccgcgcctcc agctcccgca cccgcggatc ggcggcgacc
     2461 cgcgacttga cgtcggccgc gaacaccacg gccgcggccg gcgcgccgcc cagcaccgag
     2521 gcgtacgagc cctccagcgc gagcaccgtc atgttcgggt tgagcgcctt ggagaacacc
     2581 acgaacgcac cgccgtggta gcgggagatc acgcagaaca cgatcgggcc gtcgaagttg
     2641 acgatcgccc ggccgatctc cgcgccgtac tccagctgca gcttgcgcat cgactccggg
     2701 gagccgtcga agccggacag gttcgccagc accaccagcg gccggttgcc gctggccgcg
     2761 ttgatcgccc gggccgcctt cttcgacgag cgcgggaaca gcgtaccggc ggtgtaggcg
     2821 tccggcccgt cggtgggcgg gaagccgcgc cgcggcaccg atcgcgactc gatgccgagc
     2881 agacagaccg ggtagccgcc gaggtgcgcg tcctgcacca ccacggtctc cgcgtccgcc
     2941 atgctggccc accgctccag cgtcgggtgg tcctggtcgg acagcgcccg catcacggta
     3001 cggatgtcga acggcttctt gcggtccggg ttcgccgccg agaagatctc gccgacggtc
     3061 cggaagtcgc tgcccgcaac ggaatgcggg aagtcgctga cgtcccggtc ggccgggtcg
     3121 gtcgtctccg cccgccgcgg cgccgcctcg ccgggcacca cgtacgtgtg gtcgtagtgc
     3181 gcgagcagca cgtcgtgcgc cgcggcgagg ttcggcgccc agtactgggc ctggccgttc
     3241 gggcccatca cccggtcgta gccgccgatg ccgaagttgt cgtcggccga cacgccgccg
     3301 gagaagtcca gcgcctgctt gccggtcagc accatcgccg agtccggcgt catcaccagg
     3361 attcccttgg tgtgcatgag catcgtcgcc tcggcgttcc agtacggctg ggcgccgacg
     3421 ttgatgcccg cgacgacgac gttgatctcg ccgccggcct gggtgaactc gacgatgcgc
     3481 ttgagcgccg ccgccaccca gtccatgttc tcggtaccgg accgcatcgc gatccgggcg
     3541 ccggacgaca gcgtgtacca ctccagcggt acccgcatcc gctcggccag gtcgagcgcg
     3601 gcgatcaccc ggcggcactc cggctcggac agcgcgccga gcgacttggt cgggtcgccc
     3661 agcagtacca cccgggtgac gccctcggga tgccgccgcg tgacggtggt cgcgacgccg
     3721 gcgacgatgc ccgcggtgtt gcggcccttc ggccggtgca ccggcaccag cgcgtgcgcg
     3781 tcgtccagat cgtgctcgac gaactcgccg agcagctcgg tcacctcgta cgggtagacc
     3841 gagttgcggc tgcgcgcccg caacgccttc agccggtagt cgtccagcgg ctcgagcggc
     3901 tcgtccgacg gctcgccgaa cacgacctgc acgccaccgt tggcgtcgaa gcagatccgc
     3961 atcgcgatct tgttcagcgc accggtctgt gggtcccgcc gccgcccgat gaacaggatc
     4021 tcctccagcc cggcgcccgc ggtcgccggc agcacccgct tcgcgatgat gtcgagctcg
     4081 tcgtcggtca gctcgcttgg cggccacacg tacagcacga tccggttggt gttgaagcgg
     4141 ttccgcggtg accgccggga ctgggcccgc cggatggagt cgacgcaggt ggcgacgacg
     4201 tcctcggcgg tcggcaacgc caccagccgg ccgtcctgct cccgcagcgg gctcagatcc
     4261 cgtacctggg cgaacgcgac gagccggtcg tccgacgggt tgtccgccgc gacgcactgg
     4321 aagaggtaga cctcctcgtc cgaggacggc agccgggtca ggtcgtaccg gttcagccgc
     4381 tccagctgca tccgctgcgc gatgtacggg tgcaggccgc ggatcagccg gtcctcggtc
     4441 atcccggtgg gcgaggcgcg gaaggtgaag tggtggtgca tcgcgccggc gcggccgccc
     4501 gccagggtca ccgtgagccg gcgcacctgg tacggcagcg ggttggcgcg aaccacctcg
     4561 gacagcgcgg cggccatctc gtccgcgtcg ccgggcaggt tgtcccacga caggtacacg
     4621 tcggcgtcga tggtggtgtc gccggtcgcc agctgttcca gcccgcgcag cgcgtcaccc
     4681 agccgttcga accgcaccgc ggccgacacc aggtaggacc cggcgcgctc ggcgaccacg
     4741 aacgtaccga gcgggacccg gctggcccgg acgttggtca gccccttgtt cccgtagtac
     4801 cgccgggtca gcacctccag catcacggtg ttgtccttct cggcccgcgg cagccgctga
     4861 ccgagcagcc gcaccagcgg ctcggtggta cggaccatct cggcgatccg gtcggcccgg
     4921 tccggcgcgt ccggatgcgc gtccaggtag cgcaggtgcg cccgcacctt cgcgtacacc
     4981 ttggcccggg tgcggcgcag cagcggctgg ccgaaccagc cgaacaccac gccgcgggcg
     5041 agatcggaga ccaccgggaa gcggagctgg gtggccgaca ccagccgctc cagcgccagc
     5101 ccggtcggct cgcgcagcgt cccgtccggc ggcggctcct gcagccaggc gcgcagcagc
     5161 gcggtgacca cgcccgcatc ggtggccgac cgctgctggg ccaggaagat ccggaacacc
     5221 gccgcttcca gctccgggct gcgggtcagc tcggtcacgc cgtagtgcgc cagcgcccgt
     5281 tgcagcttgg cctggaacga gtcgggcagc ccggcccgct cgacgtccag gctctgcagg
     5341 taggcgtgca ggtactcgcg ggggctgtgc acgtgggtgt cggtgccgtc ctcgtcggtc
     5401 ggccggttgc ggctcagctc ggcgagatcg gcgaaaacct ccaccagcgc cagctcaccg
     5461 gacagcggcc ggtgcccgga cgcgacgagt tcgcggcgcg cggccaggta gtcgtcgagc
     5521 acccggcgct cgtcgtgcgg gtcgacgtcg aaacccagca gcaggctgcg cagatcctcc
     5581 tgaccgcggc ggacccggtc ggccgccggc accgtcgtcg gcccgttcgg caggtccagc
     5641 tcgaccggag cggccggctg ctcgacggcg gcctcggcgt cgtcgtcggc gagcggctcc
     5701 agccgcagca gcggcgcgcc ggtttccacc tggctgccca ccgacaccgt gcattccttc
     5761 agccgggccc ggaacggcgc ctgcagcacc gtctccatct tcatcgactc cagcaccagc
     5821 accggggcac cggcctcgac ctcgtccccg accgccagcg gcgtcgccac gaccagcgcc
     5881 ggtaccggcg agcggaccac gccgccctcg tcccggctga cccggtgcgt caccccgtcc
     5941 acctcgacca ggtgcaccgg cccgtgcgtg tcggtcagca gctggtaccg ggcgccgttg
     6001 accacgatct ggccggagta ccggtcgaac cggtccagct cgacgtctgc ggtacgcagc
     6061 tcgccgcccg cctcgatgcc gacccggaac cggtgcgcgc ccacccgcgc gacccgtacc
     6121 cggtagccga cgttgcgcag cttgagatcc agcggccggc cgctgtcgtg ctgcacctgc
     6181 gggcggccgc cgaacgcggt cgacagcagc cgctgctgct cgacgcgttc ctcgtcctcg
     6241 tacacctcga tgccggcagc ggcgagcgcc accgccgagt gccggtgcga caccagccgg
     6301 ccctcaccgc ggacccggtc gatccagccg gtgtccgcgc tgccgtcgat cacctcgggc
     6361 gcgtcgagca ggtcgagcac gaagctcttg ttggtcgcgc cgccctcgat gaccacggtg
     6421 gtctgccgca tcgcccggcg cagccggccg agcgcctcgt cccggtcccg cccgtacgcg
     6481 atgatcttgg cgatcatcga gtcgaagtcg gcggggatga cgtcgccctc gctgacgccc
     6541 gtgtccaccc ggatgcccgg gccggccggc aggtccagcc gggcgatccg gcccggcgcc
     6601 ggcgcgaagt cgcggtccgg gtcctcggcg ttgagccgcg cctcgatcgc gtgcccgcgc
     6661 tccaccggcg ggttcccgac cagccggccg cccgacgcga cgtgcagttg cgccttcacc
     6721 aggtcgaagc cggtggtcga ctcggtgatc gggtgctcca cctgcagccg cgtgttcacc
     6781 tcgaggaagg cgagcacctc ggtaccgggg tggtacagga actcgaccgt cgccgcgccc
     6841 cggtagccga ccgccaccgc cagtcgctcc gccgacgcct tcagctcggt gaccttgtcg
     6901 gccggcagta ccggcgaggc cgactcctcg atgatcttct ggttgcggcg ctggatcgaa
     6961 cagtcgcgga cgcccagcgc ccacgccgta ccctcgccgt ccgcgatcac ctgcacctcg
     7021 acgtgccggg cgccggtgac cagccgctcc aggaacacca cgccgctgcc gaacgcgcgg
     7081 gccgcctcct ggctggtccg ctcgtacgcg tcggtcagct cggccccgct cgtcaccacc
     7141 cggatgcccc ggccgccgcc gcccgcggtc gccttcagca tcaacgggta gccgatctcg
     7201 gccgccgcgg tcagcgccgc gtccagcgtc tcgaccgcgc cgcggctcca cggcgcgacc
     7261 ggtacaccga cctcctcggc cagcagcttc gcgccgatct tgtcgccgag ggtacgcatc
     7321 gcctcggcgc tcgggccgac gaacgtgacg ccgacctgct cgcacagctc cgcgaacgcc
     7381 gggtcctcgg cgacgaaacc ccagcccacc cacgccgcgt ctgcgcgggt ctcgcgcagc
     7441 gcgcgctcca gtaccttcag atccaggtac ggccgggccg acgccgggcc gaggtcgtag
     7501 gcgtggtcgg cctcacggac gaacgtcgag gcccggtcga cgtcggtgta gagggcgatg
     7561 gtctcgatcc ggtgcccggt ctgcgcggaa agctcccgcg cggcgtggat gagccgcctc
     7621 gcggactccc cacggttgac gatggcgaca cgactgaaca cccgacccag cccttccgta
     7681 gacgacgaag tgcgcgccgc gccgcggccg ccccggtcca ccctgacgcc tgccgactcg
     7741 tcccgccatg gagcaactaa cgcacgttca ggacgcatcg ttgtaggaac ccaccaaaag
     7801 ctctcggcca gctccaccaa tccgatccga cgaaccgatg ctatggccac ccgacggcgg
     7861 cccaccatgg tggttcaccc agcgttgcga ccgcgacagt ggcgcggcgg gatcgaccgg
     7921 catgtccgac tcgcccgcgc tcatccggcc ggggccgcgc cgggcagcgc gccggtgtcg
     7981 acggtgacca gtaccggccg atggtcggtg tcggtaccga cccgtccggg atcggccacc
     8041 gcgtagccgg cgatcgccgc cgccggaacc cggtgggtgg cgtaccagcg gtcgatgcgc
     8101 cgcggcggct gcgggtcgat cgggtggtaa ccggtggtgg gctgccacgg cgcgccgaaa
     8161 agcaccgcgc agtcgcgcat cccgccggcg ttctcgagca cctccgccgc accgcggtcc
     8221 acctgcccgt cgccgccgag ctggtagccg tgcgccggat gccagaccgg cgccggataa
     8281 ggggaccggt cgtagtggtg ccacccgtcg ccggtctcga tccggctggc gccgatgctg
     8341 ttccagtcgc ccccgacgaa cccgggcagc gtgtcggggt gcatcgcggt cagcacctgg
     8401 tacgcgtcgg cggcccgcca cggcggcgag tgcggcgaca ggtgcaccga cccgacccgc
     8461 agcggcgtgc cgtcgatggt caggacgcag gtgaccatgc cgtgccacag gccgtgcgag
     8521 gcgcggccca gccggaccag gcttcccggc cgtaccgacg cccgatccgc gcgccacagc
     8581 agacccgcgt ggtaccggcc gccaccggcc gccgccgcgg cccggccgtc gacctcgcag
     8641 tacagcccgg tccgctcggc cagtcgccgc agcgccgcgt ccgcgccggc ctgccgggcc
     8701 ggttcgtcgg cgccgtcggc gatcagctcc tgcaccgcga ccacgtcggc gttcaggccg
     8761 gcgaccagct cctcgacccg ccgccaccgc tccggctggg cggcctgctc gtcgtagagc
     8821 tgccaggcgt tcaccgtggc cagcgtgatg atcatccccc gaccgtaccg atgatcggcg
     8881 agatcgggcg acgcggcgac tcagtcgtgg tccggcgccc cggtgaggtg atgctgggcg
     8941 gcggcgagga cctcgtcgac cagccgccgg acgtggccgc cgcgggcgcg gtagagcgcg
     9001 cggcggccgt cccggcgggt acgcaccagc ccggccagac gcagcttcgc caggtgttgc
     9061 gacaccgccg gacgggccga gccggtggcg gcggcaaggc tgccgacgtc gagttccgcg
     9121 tcgcgcagca ggcacagcag ccgcagccgg gtcggatcgg cgagcaaccg gagggcggtg
     9181 gcagcggtct cgatcagctc gtcgtccggt agctgttgcc gcatctcggt cggccgccgg
     9241 atcggctccg ccgccctggt cgccgacggc ctgcacgccc gcaccgacgg cttcacctcc
     9301 ctcaccgtac tgctgggcgc cggcggggtg gccatcggct ggagctgggc cgatcccatc
     9361 gtcggcctgg caatcacggt ggcgatcgcg ttcgtactca aggacgccgc ccgggagatc
     9421 taccgccggc tgatggacgc ggtcgacccc gacctggtcg acgccgccga gaccgcactc
     9481 gccgccaccc ccggcgtccg cgtcgtgggc gcgctgcggc tgcggtggat cggccaccgg
     9541 ctacacgccg agaccgacct gaccgtcgat gccagcctgt ccgtcctcga cgcgcacgcc
     9601 atcgccgtcg acgccgaaca cgcgctgctg cacgccgtac cgcgactgtc cgaggtcacc
     9661 gtccacaccg accccgccac cgacaacgcc cacgaaccgc tcgcccacca ccgctaggcc
     9721 gggtccgcga agccacacga acccgcggcc ctctgacact catcgtgttg ccgaaatcac
     9781 ccgatgtatg agtgtctggt gatgcggcga tggaactcgc catgagctat tccgcaacaa
     9841 cccgctgctc cctatattga tcctcatgac gtttgtggct cacatggtcg ttgtatcgcc
     9901 tatcgagttc agaggctgaa atgggcagta acccaccgtt atctttgagc cgtccgggga
     9961 ccgtttcatt gcttcgtatc ggaacaggct gtgaccgtcg atgagcctgt cgccattcac
    10021 acagaggccc atcctgggcc gcgcgatggg cgagtacctc atcgatatct ggactacggc
    10081 gtgtgaaacg ctgggtctcg ccgccgagca atggcagcct cccacgcagg agttgcagcg
    10141 gttgttgccc gactgggccg acgaccagat ccaggcggcg ccccgcgaga cgtcctacgt
    10201 tgccgatgac ggcttcccgg cggaactgtc ggccaactgg tcgggggcgc atccggaact
    10261 gcggatgctc ttcgactgcc tgtccgatgt cccgcaccgc gccggggtca ccgacccccg
    10321 atcgagcctg tggtccggct cgtcgctgtt cacctcgatc agccggctct tccggcagcc
    10381 ggtcgccgca ccgctgtggc attcgatggc ctggcgggcg ccgaatccgc cggcgcacaa
    10441 ggtctacttc ggactgtacg gatggcctct cgcgcgacgc ggtgcggtcg tcgaccgggc
    10501 catgcagctg gtgggtctgg gtcgggcctg ggagcacgcg cggcaccgga tcgagaacgg
    10561 cgcccgctac ggttcgcgcg agatcgagtt cgtcggactc gacatcggcg acagcgcggt
    10621 ggcacgggtg aagatctact accgccatca gggcgtggac gtcgccgaga tgaaccgcgt
    10681 cgcctccgtg gcgttgcacc acgacgaggg ccgcgcgctc gccgcctacc ggatgctgac
    10741 cggcggccga gacgacgccg gtgacgcacc gttgacctgc ctggcgtttc gttccggcta
    10801 tcagcaggcc gtcgaggcaa cgacgtatct ccgaatgccg agcctgacaa cgtgtgaaca
    10861 ggagtcggtc gagcgcacat ccgcgctgat ggagtcggaa ggcgtaccgg cgcaacggtt
    10921 cgtggcgctg acggaggcgt tctcgccacg ccggtccgac ggcggccgcg gtgtgctgga
    10981 gttggtcagc catcgcgccc gccgcagcgg cgacgtgacc acctactttc ggttccccac
    11041 gttctcgcag ccagccgcgt tgccggtggc gtccgcccaa cgagcatgac ccgtagaaag
    11101 gagtccacca tgagccagcc cgaccgctcg aacgtggatc gcgttgccga gtacaacaac
    11161 cagcggcagg agcagtaccg tgcgtcgcgc ctgtgccagc tgctcctcga cgacacggtg
    11221 gccgaggaaa cgaagaaggc gacattgcct ctcctgcagc cgtggtccaa tgcgttccag
    11281 cgcatgatca ccgcgcgggt ccaggcggag gcgtcccgga ttcagaccga ccaggacccg
    11341 gagctgctcg ccctggcgat cgagcactgg caggaagagg tcggccacaa cgacatcctg
    11401 aagcgcagcc ggggcggtac ggaccaggtc atctgggatc cggtcatcga ggcgggtgcg
    11461 gcgtggttca tcgaacagtt ccgcaccctg cccggcatgc agcgcgcgat gctggcccac
    11521 ctcgtactgg aagcgggcag cctggtgttc agtcaggccg gcgtccgcgc cttcccgcac
    11581 gacgagtact tcgccaaaca cgacgaggat gacgtcgagc atctggagat gggttatcgg
    11641 ctgctgcgaa gccgatcgga ctggtctgtc gacgagatgg tgacgatcat ggatcggggc
    11701 tggcagatca tcaccctggt gtccgaccgg atcgccgagt gcgccgtgcg cgacaccgcc
    11761 gcagcatgat cgatacagca caggatcggg cccggggggt ggcgctcggt gccgcccgcg
    11821 tctggcaggc cgcgttcggc gagcggctga ccgcggcgta cctgctgggc agcctcgccc
    11881 acggcgggta ctcgccgtcg gcgagcgaca tcgatctcgg catcgtcctt tccgaggtgc
    11941 ggcccggcga ccggcaactc gccgacgact gcgcaacctc ggtgcgggag caggccggac
    12001 tctacgggaa ggtgtcggcc ttctgggcgt cgctgcccgc gctgcgcgac ggccgggagg
    12061 atggacggtt tccggcactc gaccggctcg atctggcaga tcacgggcaa ctgctgctcg
    12121 gcatcgccgt gcgcgaggcg gtcgcccgtc ccgaccggac cgagttgctg ttgagcagca
    12181 gccggttcgc gttggagatc ctcgcggtac cggaggtcgt ggcggagttc caccagccac
    12241 agcggctgct gaccgacgtc gtcctgttca ccaaggccgt gctgttcccg gtgcggttcc
    12301 tgcacgcgac agcggaagac ggcggtgcgg tgggcaacga cgtcgcgctc gactggtacc
    12361 tcgcgcagcc cgatcccgtc tcggcgccgc tcgtgcggct cgcggcgtcg atccgcgcgg
    12421 gtgcggcgct agaccccgac aaggcgttgc cgctcttggc cggcctccgc ccgctgtacc
    12481 ggtgctacat cgacgatcgg gtcgaacggc tgcgcctggc cggtgcgccg gacgacctga
    12541 tcagcgggtt cgccacctgg cgagaccggt tgcgggactg acagcggcga tcacctggct
    12601 gccggttccc cgaccaccgg cagccgcgcc aaggcatgtt cggtcaggcg gatcagggca
    12661 cgccggaccg actcgcgatc gcgggcgtca agccgcacga acggcacctc cgtaccgagc
    12721 ttcaacgcgc tgcggatctc gtggtcctcg taggcgcaga caccgtgaaa catgttgacg
    12781 cccaccacgt acgggatgcg acgcgcctcg aagtagtcga tggcggcgaa gctgctgttc
    12841 agtcgcgccg gccgagggtc gacgagcacc aaggcgccca gcgcaccgag cgccagctcg
    12901 tcccacatga accagaaccg gtcctgccca ggggtcccga acaggtacag gacgacttct
    12961 tcgttgatcg tccgccggcc gaagtccagg gcaacggtcg tgttcgtctt gctctcgaca
    13021 ccggcgaggt cgtccaccgg cttactcgct tcagtcaaca gctcctcggt ggtcagtggc
    13081 gggatctcgc tcaccgaacc aacgagcgtg gtcttgccgg tgccgaatcc accggcgacc
    13141 acaatcttga ccgactgcgg ctccaagatc gttccttcct cacatcacat ggcgcgcagg
    13201 ccgtcaagga cctggacgag tctgtcccgc gtgggcgcag cggagctcgt ggttccggag
    13261 ctgagtgcca gcacgccgcg gtcgatcaga tcagccaact gccttttcgt gatcgtcaac
    13321 ggcaccttgc cgatcgcaga gatctccgcg acggtgagcc atcgttgaca cagccggagg
    13381 atctggacct gatgcggctc gaaataggtg gggtcgagat ccgccgtcgt cgctctcacc
    13441 atgctgccca gattcaagtc actggaaatg tcggcggttg cgcggcggcc ggcaaccgcg
    13501 tagagcggga ccagcccgcc ggcgtcatcg tcgacccatt cgtcattctg cccggccata
    13561 aggctatcct tccaaaccgc cattcagggc ggctgtcgtg tcgcgaggct gcgatccgag
    13621 gtgcaccccg acacgcttca ccagacggtt catctcgtaa ccgacctggc cgagatccgc
    13681 gttgacatcg gcgagtaccg cgaggcacgc attcggtccg gcagccgtga tgaccaggta
    13741 cgcgtccttc atttccacga tggtctgctg catcggtccg ctaccgaact gccgggaaat
    13801 cccgcgggcg atgctcgcca gcgaggaggc gcgggcggcc agcgagtcag cactgtcctt
    13861 gctgattcgc cgcgatcgct ggatgagcat gccgtcggtc gacacggcca cggcacacag
    13921 ggcattgaga ccatcgacca gatcgtccag cgcccagtcg acgttcatcg gtgtggtggg
    13981 agtctcactc atgatgcttt gccgtttcct gtcaaggggt gtgttcagtt gtcctcagcg
    14041 cggccagcgt tgctgccctg ttggaaccgt gccaaccggt tgcggatgag ttccggatct
    14101 cccatgtcga tcgcctgctc cggcgtgccg ggatgctcca gatcctcacg cagctgcggc
    14161 gcgatgtgct gctgcggttg ccgctccggc agcggcggcc ggcccggccg cgcatcgcgc
    14221 tcggggacct gtggctgctg cctgatcgcc gtgacccgcg ccggcggctc cacaccgatg
    14281 tcccgagcac ccaacgaagc gtgccccgta ccgggctgga tgcgcggggc cgggctgacc
    14341 ggccgagcgg tcggcgcagg gcggtgcgcc gagccgctgt cgagccggtg cgcggcaccg
    14401 ttcgtcgaca ggccggggcg tcgcggcgcg ggcggggcac cgacgaacgc gggcatctgc
    14461 atcgtctgct cgacatcgcg cggcacatcc acactctcgg ccatgcggga gatgtcgcca
    14521 ctgcggtcgg ctgcgttgtc cagctgtgcc ttgggaatca agacgaccgc cagcacgccg
    14581 ccgtagggcg aggtggtcag cgtcaccgtg atcccgagct gcttggcgag ttgcgcgacg
    14641 acccagaacc ccaactgcga cccgtcgccc aacgcgttga cgttgaactc cggcgcctgc
    14701 ttgagcatcg cgttggcctg gtcgagatcc tcgggcgcca tgccgatccc tcggtcctcg
    14761 acctcgatgg caataccccg gtccacgtac acaccacgca cccgcacgtc cgactcggtg
    14821 ctggagaagc cgatggcgtt gttgagaagc tgcgtgagca gatggatggt cccgttcacg
    14881 gcgtcgcccc gcacccgaac ctcgggcgcg gtctccagct tgacccggtc gtagtcctcg
    14941 gcctgcgcct tggcagcctg catcacctgc agcagcggaa tgggcgtctg gaacttccgc
    15001 cccggcttac cgccaccgag gatgatcagg ctctcgttga cgccccgcac ctggttgacc
    15061 cggtgatgga cccggaacca cttctccaga cgggcggggt cttcctccgc ccgctcttcg
    15121 gcatcgagtg cacggctcgc ctgctgcagc ggacgctggt tgcggtatgc gatgccgagg
    15181 aacacacgca gtaccccggc gcgcgcctgg ccctcactca ccacggcgtc ggcagcaagc
    15241 acgacggcgt cgttgagcgt cttccgcacg ttgtcgatct cgtcctgtcc ctgttcggct
    15301 tcctcgtcag cagccgagtt gatctggccc aactcctcac gcacgttgac ccgctcaccc
    15361 gccgccagtc gttcccggat cgccgggaag cgcgtccgca cgatgaggtt ggcgtcctca
    15421 ccgagctggc ggatacgagg gatcagcgtc cggccgacca gaacactgga ccggcgcagg
    15481 gcccacagaa tcgccagggc caccaccgca gccgcggcaa cactgccgcc gatcgcccag
    15541 ccgaggttct ggtttccgct ggccagcccc tgcgcggaga cctcgtcggc ctgcgacttg
    15601 gccagctcga tcaggtcgtt ggagacctgg tccgtcagct tgccccacgc cgccgaatcc
    15661 accggaagcc cggtggggac gccgccttgc caggcaccgt cggccaggat cgcgtcctcc
    15721 gcggcggaca ggcgggacca ttcgtcgctg cgcatcatgc gacggactcc ggcacgaacg
    15781 tccggaagca gatccgcctc gacgttgctc agctgcgaac ggtaggcgcc gaccagttgg
    15841 acgtacgtca ggtagtcgtt cgtgctgaac ttcttcgcgg cgaaggcacc ggcggcctga
    15901 gatcccgcac gcgacatcag gtcggacacc cggaacaggt ccgtggcggc gaagccaccc
    15961 tgcgacgcgg ttgcgtcggg gatgatccgc gcctgggtgt tgaacagttg aatggaagcg
    16021 tcgaggatct tgttgtagaa cgcgtagacg ttctgcgggc tgatggttct cgcgtcgatc
    16081 tgcgcacgga ccttcggcag ctcgtggagg tagcccgtga cggtcgccat ctggtccttg
    16141 atcgacgcgg gggcgctgcc cagtgctgcc ttcgcggcgt tctgcatcga ggccaggccc
    16201 tcgtcgctgg tcgcgcgttg cgcgttcagc gaccgtgttc ccgccggcgt ccccgccgag
    16261 ttggccagct cggccatgct cagctgacgt tccttctgca aggaggcgag gccgttcact
    16321 gcagggatcg acacctgccg cacgctcgaa gccacctggc gcgcatagac tccggtgtag
    16381 cccaggtacg aggcgccaac cagccacaac gcgatcaacg cgacgctggg aaccagcgcg
    16441 acgcggacaa caccttgccg gatcgatcgt tggcgccgcg gccggcggtc gcgacccgcc
    16501 tggcgctgat gggtctgctg actagtcatt gcgctccatc aacaacggtt gacatattgc
    16561 aagcgcgtgc ccccgcaccg gcgccgttcc cgcccacaca ctgtgccgcc acgtcgtacg
    16621 agcccaccga cccgcgttca cgatcgccgt cgaggcctca gccaccctca acgaggcaag
    16681 gcagccccaa tgacggtgtt gacggaactg tggcgagttg tgccatgcac ggccccgcac
    16741 tctaccctgt ccgaaatcgc gccagacacc tcccgcgcgc gcctcggcgg ccccagcagc
    16801 cgccaccgcc gcgtgccgag cctggcatta caacaccgat acgggccgtg cgtagcccgg
    16861 caacctgcct tgatcggacc cggccgggac gccgtcgaga gtcacggctg gccacgctgg
    16921 tcaacccgca cgacggcggc gcgcgagccc accgccgacc acagtcacgt gttcaacctc
    16981 acccccaacg aggggctcag gcgctcgcaa acacgccagc acgccctgcc gacgcgattc
    17041 agatgacgaa catctcgagc ccagtatttg agacgacgcg gctgcccggc cagcgaccag
    17101 cgcagtcagg ccgggattct tggcgtcgtc gtcgcggaca tcccccagca accgaacggg
    17161 gacccgattc tcaactgttc gtaaagcttc cttcgctaat atctcgtccc gagaaatgag
    17221 gcgggcgccg ccgctgctga agatgcgaat ccaccgacgg cggcaccggc aatcctgggc
    17281 atgctcccgg tgactggcac acggcgggtc cagccggtgg atgcctcacc tgcggcgcgg
    17341 gaacgggcgc gcgctgggcg ccttcacgag gcagccagtg gtggcgggcg gagcagtggc
    17401 tgtcgtacgg cggcccgatc cacgccgacc ccaggaccgt ccatgccacc ccgaccacga
    17461 cccaggtggc acccgctgaa cggcacgcgg cgagccgcac cgcatctccg tgccacgaca
    17521 gcggcaccag ccgctgctcg caccgccccg ccgggggtgt cgcaccgccc aggcaacgcc
    17581 gtgaccagca cagatacgca ccctcaggcg tgtggaccgc gtacccggcc acctcgagct
    17641 ttgaggtagc ctgtcccatg ccgggtcgct agctcaattg gcagagctgc ggacttttaa
    17701 tccgtaggtt gtgggttcga gtcccacgcg acccaccctc tgacctgaga aaacaccctc
    17761 atgggccagt ttccgtggtg ctcggggtcg gcccgaggtc cctggttatg ccagttttcg
    17821 accggtttca cgttgagtca taacatggct ttgacctgcg ggaacgctgt aatcgccggc
    17881 gcgattatcc gtctgatgct acacgccgcc cttcgccctg acatctcgtt gactgggcga
    17941 ggctcgccat ttctttgccg ctagtgccgt tgacgcggcc cgatttggga attctcttac
    18001 gtcgccgtga ccttcctgcg cttcaggccc agcaacgcgc aatgccgaaa aagagcattc
    18061 acgattcgcg cgacgtaatc gccgcgatat tggcgaatgg ccaaagggcg aaccgttgag
    18121 gtccccaatc gagctccagc ggcccggcaa actcctactg gaccggccag agcgatcctg
    18181 ctgcgctgcg cgatcagcat gcggggcccg acagtccgag gcgagcccgt gagatcagcc
    18241 gaaggccacg gagtgattcg accggtatgg gaggtctgat ccacaccttt gtgcgacacc
    18301 ctgtcgtatt aaagggggtc gctggcaata ggtagtgggt gcacgggcag cgccagcgct
    18361 ggcatgcctc atccgaagac cgctccaaca aagccgtaga acacctggca cgagcggatg
    18421 tcgtcgacgg acctgcagcg tgatgcacac cagaggaacc tcaccaatga gtgcgatgcg
    18481 acctgcgcgc cgagtgcggc gcttggacga cgtccgccgg ctgggcgtga cgaccagcct
    18541 ggccaccgcc gcgcagatcc tgggaggctg ctaccctacg gcccggcgtc tcgcggtggc
    18601 cgggacgttc cccatcccgg caatccgtct cggacgacgt tggagcgtac ccaccgaacc
    18661 gcttatcgct ctgctgacga ccagactgtc gccgccctca agcgataccg cgcccacgcg
    18721 cagccgaacg taccgctgca ggcgatgcgt ggaccgagac cgggctgctg ttcgtcaacc
    18781 cggacggcac cacactgcac ccatctcgca tcaccgacgc gttcgccatc tacctgcgcc
    18841 gagccggact cccgccgatc caactccgcg acttgcggca cggcaccgca accctcacgc
    18901 tcgccgccgg catcgagatt cgaaccgtct ccgcgatgct gcgacactcc tcgatcgcgg
    18961 tgaccggcct ctactccagc gtgaccaccg ggctcgccca cgaggcagcg ccaaccatca
    19021 acgatgcgcc ccgggcccgc tggagaggcc gtcacggccg gcgaaccgcg ccacaacagc
    19081 aacgctgacc acttctcggc gacgccgcct cccaccggtg gtggtggttg acggctgcac
    19141 gctgcgcgtg ctgtactgaa gctggttcac ggtttttgtg gtcgtttcat gaggcgctcg
    19201 caaagattga cagcgggcgc ggtctcttct ctttcctgtt gagtcgtgtg cgttggccgg
    19261 cgtatccaaa tggctgcgcc ggaggctcga tgaggaaaag aggcaacatg gcgcaaggca
    19321 ccgtgaaatg gttcaacgcc gacaagggat tcgggtttat cagcccggac aacagcggtg
    19381 aggacctgtt cgttcacttc tcctccatcc agagctctgg attccgcagc ttggatgaga
    19441 acgctcgggt gcagttcgaa atcgagacca ccggccgtgg cccgcaggcg atgaacgtct
    19501 cgacgttgta aagacccagg gaacgggtgc ccgatgcttc gggcacccgt tcttgctatc
    19561 tatcagccgg agcgatggcc acatcggccg atcgggccgg atcattctgg caagggagtt
    19621 gctattacag ctatgggttt gcgctcgacg caggtcgacc agcgtcgagc ggctcaggcg
    19681 gatcagttcg ccgggtcgta caaagcggtc gcgcaggttg ttcgggagct ggggctactg
    19741 cgtcgggccc gctggttcta cgggttgctg ttcggcgggc tgtgtctcgc gctcgccggc
    19801 gcggtcaccg gattcgttct gctcggtgac tcgtggtggc agcttctgat cgccgcaaca
    19861 ctgggcgtga tttgcacgca gttcgcgttc ctcgcgcacg aggcatcgca ccgccagatc
    19921 ttctcgggcg ggccggccaa cgaccgcgcc gggcgcttgc tgggcactct gctggtgggt
    19981 atcagctact cgtggtggat gggtaagcac acccgtcacc acgccaaccc gaaccgggtc
    20041 ggcaaggatc ccgacatcga aatcgacacg atctcgttcc tggccgagga cgccgctacc
    20101 cgccgcggcc tgctggcggc gctgacccgc cgccagggct acgccttctt cccgctgctg
    20161 atgctggaag ggatcaatct gcacgtcagc tcgatccgat tcttggccgg ccggcgccgt
    20221 atcacgggcc gctggacgga gttggggctg atcgccgcgc atctcgccct gatcgctacg
    20281 ccggcattcg tcttcctgtc gccccggatc gccggagcat tctgtggcgt ccagctggcg
    20341 gtgttcggcg tgtacatggg cgcctcgttc gcgcccaacc ataagggaat gccgatcgtc
    20401 ggtgccgacg agaaactcga ctttttcacc aaacaggtcc gcacctcccg caacattcga
    20461 gggcgtttct gggcgagcgc gttgatgggt ggactcaact accaggtcga gcatcatctg
    20521 ttccccagca tgccgcgccc acacctggcg aaggcccgca gcgtcgtacg cgactactgc
    20581 cattcccggg gaattcctta caccgagacg tcactgccgc gctcgtacgc gatcgtgatc
    20641 gcctacctca acgaagtcgg cttggccgcg cgcgatccct tcgagtgccc catgctcgcc
    20701 ttgcgtcgct gacagccaca cgcgcagcag cttccgatcg cagcccaggc tgggcaatcg
    20761 ttgagggcga acaccattcg ccgcgcgccg ccaagccgag tgagcgcccg cgttcgtgac
    20821 ggtaaccgag accgagcagt gtgccggcga cgccggcggc gacgggccga cggcccgggt
    20881 acgggccctg gcgaaggcca ctgccggtga ccatgcggcg gcccgggcgg ccgtgatcga
    20941 gtcgctgctg ccgctggccg accggctggc ccgccgctac cgcgggctgg gcgtgcagct
    21001 ggaggacctg cgccaggtcg ccgcgaccgg gctgatcaag tcggtcgacg gctaccggcc
    21061 acagctgggc cggttcatcg cctacgcgg
//
