LOCUS       NZ_AP023354            24074 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Actinocatenispora sera strain NBRC 101916 chromosome.
ACCESSION   NZ_AP023354
VERSION     NZ_AP023354.1
KEYWORDS    RefSeq.
SOURCE      Actinocatenispora sera
  ORGANISM  Actinocatenispora sera
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinocatenispora.
REFERENCE   1
  AUTHORS   Komaki,H. and Tamura,T.
  TITLE     Whole genome shotgun sequence of Actinocatenispora sera NBRC 101916
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7044238)
  AUTHORS   Ichikawa,N., Komaki,H., Tamura,T. and Uohara,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2020) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :https://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.4
            Genome Coverage                   :: 251x
            Sequencing Technology             :: SMRT cell 8 Pac V3
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018324685.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 04:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,585
            CDSs (total)                      :: 6,501
            Genes (coding)                    :: 6,404
            CDSs (with protein)               :: 6,404
            Genes (RNA)                       :: 84
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 26 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 1 of 97
            Pseudo Genes (multiple problems)  :: 10 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:48:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 345649
            Orig. end                         :: 369723
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP023354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Annotated at DFAST https://dfast.nig.ac.jp/
FEATURES             Location/Qualifiers
     region          1..24074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14074](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    275..287
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(1077..1661)
                     /locus_tag="Asera_RS01585"
                     /old_locus_tag="Asera_03220"
     CDS             complement(1077..1661)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="Asera_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03220"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_084132918.1"
                     /transl_table=11
                     /translation="MAVRLVPPSETLTAPGLLLRRWRSGDVRAIVRAVQASMPELSRWM
                     PWAVEGYGATEARAFLDQGRQQWDESQAFNYAIVRGGDVVGGASLMARVGPGALEVGYW
                     VDSRHTGRGVARRAAAALAAAGLAVPGIDLIEIHHEPANAASAAVPRALGFERVDDIVN
                     EDGRPTGVWQLHAGRLADSRIPDLLDQRRYR"
     misc_feature    1729..1740
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.51"
                     /tool="antismash"
     gene            1797..2930
                     /locus_tag="Asera_RS01590"
                     /old_locus_tag="Asera_03230"
     CDS             1797..2930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012180652.1"
                     /locus_tag="Asera_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03230"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_030449885.1"
                     /transl_table=11
                     /translation="MPEPLAAALADLRTLLTDSDRLVRAVAAGRRRGVTPEVPRVELRP
                     VRIGAGPRLQIVEQDAARPRTRNVAWGADAEAAVAELLARPYGNWHVTGTDATVQLRVT
                     KRGEAQVHRSAGAGTPADTEHDRAKSYLLPPDDELYGVIGGNAAKRRQVDAFLRALDAT
                     LPAQLPEPLRVVDLGCGNAYLSFAAYRYLTDRRGAHVQLTGVDIRADQRDRNTALADRL
                     GWADRVSFVAGTIAAAPVDGADVVLALHACDTATDDALARAVRWQAPYVLAAPCCHHEL
                     SGQLRDRTDPLLRSAILRERFADVLTDAMRAELLRALGWSVEVVEFVDSAHTPRNVLLR
                     GTRGGVDTAAARTGYQTLSDTWRVSPALGRQLADLLS"
     gene            complement(2887..5190)
                     /locus_tag="Asera_RS01595"
                     /old_locus_tag="Asera_03240"
     CDS             complement(2887..5190)
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454944.1"
                     /locus_tag="Asera_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03240"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_030449886.1"
                     /transl_table=11
                     /translation="MSTVDSNGPAVELRIGGMTCASCAARVERKLNKLPGVAATVNFAT
                     ETARVHYPAGTTVQDLIGTVEATGYTAQPPEPPAPAADEPVADERDAAEHSLRTRLLGS
                     AVLTLPVLLLAMVPPLQFNHWQWLALTLTSPVVVWGAGPFHRAALTNLRHGAATMDTLV
                     SLGATVSYLWSLWALFLGGAGGENMRMSLHLFAGSDTGPQLYLEVGAALTTFLLAGRYF
                     EARAKRRAGSALRALLSLGAKDVTVLAADGRERTVPIGQLSVGDRFVVRPGEKIATDGV
                     VESGTSAVDASMLTGESVPVEVGPGDEVVGATVNAGGRLVVTARRVGADTQLAQLGRLV
                     ADAQNGKAQVQRLADRISAVFVPAVLVIALGTLVAWLATGRPAAAAVTAAVAVLIVACP
                     CALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRIDTVVLDKTGTVTTGRMTHTDTI
                     AAAGESPAEILRYAGAVEHASEHPIARAVASAAAAAGPLPEVADFAAVAGFGALATVDG
                     RRVVVGRPELLTREGLTVPAELTAAITTAGAHGATAVLAGWDSAARGVLVVSDTVADGA
                     AEAVAALRGLGLRPVLLTGDHEAAARTVAAAVGIDEVHAGVLPAGKADVVAELQRSGRV
                     VAMVGDGINDAAALATADLGIAMGTGTDVAIEASDLTLVAGDLRAAADAIRLSRRTLRT
                     IQGNLFWAFGYNVAAIPLAALGLVTPVLAAAAMAFSSVFVVSNSLRLFRFRAADRPGLA
                     VRTADRRAAAPARG"
     misc_feature    5171..5189
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    complement(5175..5193)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.92"
                     /tool="antismash"
     gene            complement(5228..5431)
                     /locus_tag="Asera_RS01600"
                     /old_locus_tag="Asera_03250"
     CDS             complement(5228..5431)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014690680.1"
                     /locus_tag="Asera_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03250"
                     /product="heavy-metal-associated domain-containing protein"
                     /protein_id="WP_030449887.1"
                     /transl_table=11
                     /translation="MATQTYTVTGMTCGHCASAVSTELRGLPGVEAVRVDVASGRVEVD
                     ANQPLATDAVAAAVDEAGYQLA"
     gene            complement(5459..5746)
                     /locus_tag="Asera_RS01605"
                     /old_locus_tag="Asera_03260"
     CDS             complement(5459..5746)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003089374.1"
                     /locus_tag="Asera_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03260"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_030449888.1"
                     /transl_table=11
                     /translation="MAGYWYSDDKTALLARLRRIEGQIRGLERMVEQDTYCIDVLTQIS
                     AATRALQGVALGLLDGHLSHCVAEATAKGGEEAEEKVKEATAAIARLVRS"
     misc_feature    5780..5796
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.82"
                     /tool="antismash"
     misc_feature    complement(5781..5796)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     misc_feature    complement(5785..5803)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     regulatory      5981..6115
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            6127..7113
                     /locus_tag="Asera_RS01610"
                     /old_locus_tag="Asera_03270"
     CDS             6127..7113
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013073.4"
                     /locus_tag="Asera_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03270"
                     /product="NlpC/P60 family protein"
                     /protein_id="WP_157035228.1"
                     /transl_table=11
                     /translation="MPTSAVMARPLRAFGLLLLAALTAMALLLLGTPAHATPSEAELTK
                     QIDAKSKQFDKAVQEYDKVQDQLTSSKKKEKAVNKKLKPLQKKVDAAEQAVGKMAAAAY
                     RGGKPGAVNAILSDGSASTLLDSLSLLDQLARNQSKQIAEFSKAKAALDKQKAALDTAI
                     GKQTQAKQKLADQKKSLDKDVQKLRDLRTQAYGSPTNYDTNVDYGPAPNLPGSAGKAVD
                     YAWAQLGKPYNMGSAGPDAFDCSGLTMMAWNAAGYSLAHSSYTQYSQTHRISRDQLQAG
                     DLVFYSGNEHVAIYIGGGQVIHAPTYGEPVQKASVDMMPPDGYGRVG"
     tRNA            7387..7459
                     /anticodon=(pos:353069..353071,aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Asera_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Asera_t00070"
                     /product="tRNA-Arg"
     gene            7387..7459
                     /locus_tag="Asera_RS01615"
                     /old_locus_tag="Asera_t00070"
     gene            complement(7576..8445)
                     /locus_tag="Asera_RS01620"
                     /old_locus_tag="Asera_03280"
     CDS             complement(7576..8445)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (51-133). E-value:
                     1.4e-10. Score: 33.1. Matches aSDomain:
                     nrpspksdomains_Asera_RS01620_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014444849.1"
                     /locus_tag="Asera_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03280"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_030449890.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.2e-08, bitscore:
                     32.6, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.8e-07, bitscore: 29.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTRVVPTDGAEITYDVHGPLPTADGTPPLVMIGQPMDASGFTA
                     LVAQFPDRTVITYDPRGLGRSTRSDGRVDQTPQTQAADVHALIGALDAGPVELFASSGG
                     AVTALALVAAYPNDVATLVAHEPPMLPVLPDAAAAVRARDGFLAAYQAKGWGAGMAAFV
                     AMTSWRGEFTDEYFAQPAPDPAAYGMPTEDDGNRDDPLLSDRALAITDYRPDVAALTAA
                     PTRVIIAVGEESAGTFTARTATATAALLGQEATVFPSHHGGFVGGEHGYAGQPEAFARR
                     LREVLATK"
     aSDomain        complement(8047..8292)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Asera_RS01620_Abhydrolase_1.1"
                     /evalue="1.40E-10"
                     /label="Asera_RS01620_Abhydrolase_1.1"
                     /locus_tag="Asera_RS01620"
                     /protein_end="133"
                     /protein_start="51"
                     /score="33.1"
                     /tool="antismash"
                     /translation="DRTVITYDPRGLGRSTRSDGRVDQTPQTQAADVHALIGALDAGPV
                     ELFASSGGAVTALALVAAYPNDVATLVAHEPPMLPVL"
     gene            8609..9145
                     /locus_tag="Asera_RS01625"
                     /old_locus_tag="Asera_03290"
     CDS             8609..9145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020509521.1"
                     /locus_tag="Asera_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03290"
                     /product="DUF664 domain-containing protein"
                     /protein_id="WP_030449891.1"
                     /transl_table=11
                     /translation="MDEVVIGAAPRPEPVLAGSWLTVLGGMLDFHRATLVWKCSGLTDA
                     ELRRRPLRSELSLLGLLRHLQGAERYWFGVRIGGTTPAFHPYRMYRTAQGEQWYDEADP
                     TPASEVYADYLAACAESRAVHRRLGEADLDRLVDNDEFGPASVRFVLLHLVEEYARHVG
                     HADLLRETIDGTTGE"
     gene            complement(9224..9937)
                     /locus_tag="Asera_RS01630"
                     /old_locus_tag="Asera_03300"
     CDS             complement(9224..9937)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038065.1"
                     /locus_tag="Asera_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03300"
                     /product="Pr6Pr family membrane protein"
                     /protein_id="WP_030449892.1"
                     /transl_table=11
                     /translation="MDTERALHRVGRAWHGVLAVLIGAALVAQVVLVCTGGDGDPGVSV
                     AARLVRTFSFFTIQSNILVLADCAVRAVRPAADGRLRRVLRLDALLGITVTGLVFALVL
                     AGDSHPTGLAWWLNLMFHYAAPPIAVVGWLLFGPRRRIDLASLGCALVWPLLWIGYTLA
                     HGAASGWYPYPFLNVTDLGYAATVRNLAFVVLLGLVLLGAFAGLDRLLARSRWTGGAAA
                     VPPGPVVPEPRAARD"
     gene            complement(10001..11335)
                     /locus_tag="Asera_RS01635"
                     /old_locus_tag="Asera_03310"
     CDS             complement(10001..11335)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017634.4"
                     /locus_tag="Asera_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03310"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_035298867.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 8.2e-52, bitscore:
                     175.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGHGTDVDVALVGGGGAAHCLLHALAAAGVRVSVAVLDPVSHT
                     GNDRTWCFWDGGTSPVEPAVRRRWSRLRVVGPDGGARELAPVSYAMVRSADFYREVRQR
                     CAPPAAGAAGAAGPAVRWMPASVRAIRPARADPPAGPGEGGNRPGETVAPAPPGQLAPP
                     GQPGQPAPSGQPVGLVGQDGPDTGGVVLDTDAGQVTARWVFDSRPRPPDRPGTTTLLQH
                     FRGRWLSGAGLDPAAATLMDFTVPQPESGLAFGYVLPVDRHEALVEYTVFSRSRLAPAD
                     YDAALDRLCDRLGVAGAIVESIEDGVIPMTDGRFARRVAPHVYRLGTAGGATRPATGYT
                     FATMLRQARVVAARLAAGADPVPPRPYPARHLRYDAILLRAIDRGLVDGPRLFTELLTR
                     HPPDRILGFLDGTSTRRDEARILAGTPIPGMVRATAGWLAATARR"
     gene            complement(11332..12819)
                     /gene="crtI"
                     /locus_tag="Asera_RS01640"
                     /old_locus_tag="Asera_03320"
     CDS             complement(11332..12819)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018217624.1"
                     /locus_tag="Asera_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03320"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_030449894.1"
                     /sec_met_domain="DAO (E-value: 6.1e-18, bitscore: 64.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTVPGRVDRVVVVGAGLGGLAAAIRLAGAGRAVTLLERDERPGG
                     RAGLLRRNGFRFDAGPTVLTVPQLIGDTLAAVGEELADWLTLTRLDPAYRAHFPDGSTL
                     DVRTDTAAMAGEIAALCGPREADGYLRFVDYARHLYRIEWHDFIDRNFDRPTELLTPNL
                     VRLAAAGGFRSLDAKIGQFFRDPRTRRIFSFQSLYAGVAPHRALALYAVISYLDTIAGV
                     YFPRGGIAAVAQAMADVAAKHGVDIRYGTEVTGIERRGDRATGVTTAGGQRFAADAVVL
                     NPDLPVAYRDLLGRRPRRLRYSPSCVLLHLGASASYRGIAHHNVHFGRSWRPVFDDVID
                     RGVPMRDPSLLITNPSRTDPSLAPPGHHTYYLLAPTPNLAHRRPIDWAEFGPRYAEELL
                     STAESRGYVGLSAAVTERVLVTPADWAAAGMAAGTPFAAAHTFGQTGPLRPGNRAPGLS
                     NVVFVGSGTQPGVGVPMVLVSGRLAAERITGPVPSRP"
     gene            complement(12947..14074)
                     /locus_tag="Asera_RS01645"
                     /old_locus_tag="Asera_03330"
     CDS             complement(12947..14074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="Asera_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03330"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_051803102.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-40, bitscore:
                     136.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAHPGARSGATRSRAAGPGATGASAAGIAARVDAVLDEFVTAEI
                     ATLRSLSPEVAAAAAPLRELILGGGKRLRPAFGYWGYRGVATGADEAVLRAVSALELLH
                     AFALIHDDVMDAAATRRGAPTLHRQFGERHVAAGWRGDPARFGDSVAVLLGDLCTVWAD
                     RLIGTSGVPAAVLLGARREYDEMRIEAVAGQYLDVLHGADGAPGVGTAVQVARFKSASY
                     TVQRPLQFGAALSGAVPPDVVAAYDRFGGAVGEAFQLRDDLLGVYGESAVTGKPVGADL
                     RQGKPTVLAELAFSLAAPAQHRRLDRVYGDPDASDAAIADAAAAITESGARAEAETMIS
                     ARVSAGLAALAAAPIDPVARDRLSALALACVQRLA"
     gene            14207..14953
                     /locus_tag="Asera_RS01650"
                     /old_locus_tag="Asera_03340"
     CDS             14207..14953
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015000.4"
                     /locus_tag="Asera_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03340"
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="WP_030449896.1"
                     /transl_table=11
                     /translation="MFDSTPTVLGHRGLGKGIVDGLTENTMASYRAAIELTDWLELDVQ
                     RCADDELMVYHNPATPDGVFVLEQTAAELAAKGVLRFADVLAELPTEVGLDIDVKTPIE
                     DAIAAPDRRTAALLAPVLAAELSRRRLFATAFDPALLVELKEAVPGLPTCLVHWLAYPL
                     GPAIAAAAGLGASIVGLHTDSFGPSPLQPDPAIQYDHAYAVEVAHRAGLEVLTWCPSAD
                     RAPALAKAGVDALCVNDIPGVQAALR"
     gene            15031..15876
                     /locus_tag="Asera_RS01655"
                     /old_locus_tag="Asera_03350"
     CDS             15031..15876
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012673.4"
                     /locus_tag="Asera_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03350"
                     /product="inositol monophosphatase"
                     /protein_id="WP_084132920.1"
                     /transl_table=11
                     /translation="MTEMSVQLEQIAVRAARGVGDALRAAFVQAQQPSHKRDHHDLVTE
                     HDERTEQVLRAELLDAWPDSAVLGEEGGASGDGAVHWLVDPIDGTANFALGLPFFAVSI
                     GAVANDQLVAGVVYDVMRDTAFSANLHGAYADGEPLRSTGPATDAQNMLITSYPGPGTL
                     AAGRGVEEYTTLLREFGAVRRMGSTALALAYVAAGAGCAYAYGIHPWDVAAGALIVQQA
                     GGRYLPLPDTGRPWEAPGYLAVNGDFDLPGSCLTDLLPRMLPRTATGTPLPGGGLRNRP
                     "
     gene            complement(15873..16580)
                     /locus_tag="Asera_RS01660"
                     /old_locus_tag="Asera_03360"
     CDS             complement(15873..16580)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037625.4"
                     /locus_tag="Asera_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03360"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_051803103.1"
                     /transl_table=11
                     /translation="MVSVAGLREKKKYKLRQSVQREAFRLFAEQGYAATTVEQIAEAAE
                     ISTTTFYRYYSSMVDVVLSGEYEPPDGADDLFAELGEATDITAALRSMVRRAMGSMAFD
                     RDEMLARYSLIFSVPELWAAFQHRQQQGRGQAEELLARWLHAEPDSYPVRLAVAGYAAA
                     VTETLRYWTDHHGEPDLAELLDQMIVRLAPLLRPVADDDRADAPETGDGPATDDSTVGD
                     GPATDDSTVGDRG"
     misc_feature    16540..16556
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            complement(16699..17913)
                     /locus_tag="Asera_RS01665"
                     /old_locus_tag="Asera_03370"
     CDS             complement(16699..17913)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015619756.1"
                     /locus_tag="Asera_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03370"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_030449899.1"
                     /transl_table=11
                     /translation="MTRTALVSGASIAGPALAYWLHRYGFEVTVVEKAAAVRGGGYPVD
                     VRGTALDVIRRMGRYEQLRAAHLHMGRMTFLRDDGRRVVSLRLDRLGGADGGDTELPRG
                     ALTGLLSDAIGDDVEFRFGDSIAELTDHDSGVDVRFAGGDTARYDVVVGADGLHSNTRR
                     LVFGPEEQFHHYLGHCFAGFSMPNHLGLDHEGVASTAPGRTAVLYAAGDPDRVHGFLSF
                     GRAEAPFAAFRDPAAQRELVASVFADGGWEVPRMIDAMRTADDLFFDVVSQIRMPNWSR
                     GRVALVGDAAYAPSFLSGQGSSIALVGAYVLAGELAATTDHRAAFAAYEQRMRQFVADN
                     QALAIGGGGVAVAPATRRGVWARNQLFRVAPLLLRLGAFGGRVAKVKSSLTLPDYTAPA
                     EVGTR"
     gene            complement(18137..19315)
                     /locus_tag="Asera_RS01670"
                     /old_locus_tag="Asera_03380"
     CDS             complement(18137..19315)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="Asera_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03380"
                     /product="acyltransferase"
                     /protein_id="WP_051803104.1"
                     /transl_table=11
                     /translation="MSTTDVPVAATVGRKGTWHRWAGRVDAATPVRRDRTVDALRAVAM
                     LGVVIGHWLVSALVADPGRPGVLTNHSPLSGWPGAAPVSWLLQLLGPFFFAGGYAAARG
                     SRGRAALPWLAGRLRRLVLPVLALAAVFGPVLAALPALGVPGPTRQVVWSLVSHPLWFL
                     LVYLLLTAATPVLRTLTARCGLWWLVPLVGAIGLVDTMRPAGLPSWLVLAAVPVGWAVP
                     YALGIGLAEGTLPHRAGAVLLPAGVVAGAALVAAGYPASAVGVPGDGWSNLDPPSLFTL
                     ALAAAQLGAFLLVRGRLAALLRRPAAWAPIAVLNLAAMTVFCWHQSALLAVSLAGLPFG
                     QVPGLLSPPAGDWLALRLLWTPAFGAVLAGFCLLFRRVETHAARRPHAVPPA"
     gene            complement(19312..20391)
                     /locus_tag="Asera_RS01675"
                     /old_locus_tag="Asera_03390"
     CDS             complement(19312..20391)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688003.1"
                     /locus_tag="Asera_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03390"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_084132922.1"
                     /transl_table=11
                     /translation="MRSRLGRWALAVLSAVLVAAPAANAVLDGPATAGPAAVPIGTAAW
                     RADPRHLPDPATATPAAVHAALAGAPRSLATRYPGVVGELDGAPIALRYQANRAAMAAA
                     GAPYAGWHGRYLLFDPRGDGRVAQVFGDLSTADRIAVLVPGVDDRLANFRRGLGGKAYR
                     SPAVQAANLYRASGARIAVIAWLGYATPRGVGIDAARERLAATGAVALRRFVAGLTAVR
                     PHATIALLGHSYGSTVLGLAARYLPRQVTDIALFGSPGVGVGTASALHTPARVWAGQST
                     KDWIRYVPGLRLFGFGHGRKPADPAFGARIFPTADVGDHDHYLAPGTDSLAALARIALG
                     PGHFAPARTALAASGGGAA"
     gene            complement(20499..21836)
                     /locus_tag="Asera_RS01680"
                     /old_locus_tag="Asera_03400"
     CDS             complement(20499..21836)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="Asera_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03400"
                     /product="sensor histidine kinase"
                     /protein_id="WP_157035229.1"
                     /transl_table=11
                     /translation="MQNQRWRQVTAAAWRGLRQLLYGPDTPIRWPVGRGRWLRWAARIA
                     VVAAIAVLYPVTMVTVLNAHRGEQSAIVLILAVVQLLPLVLALRYPLMGWRIGVLAALL
                     APAVRTAPVWGSWPWEPAQIPILAVAFVLAGLRYQRAVLWWMWAAMAGVLVVHVDAGNA
                     PGGLAVLTIGAVLVDLIRSRLRAQRALVAETERTELEKARRAALEERTRIARELHDVVA
                     HHMSLIVVQAQTAPYRRDDVSPGAAEELDSIAAQARSALVEMRRLLGVLRSDEDALRAP
                     QPGLSDVDGLVAGGRRAGVRISYRAEGLEHRPPTAVQVCAYRLVQEALSNATRHAAGAP
                     VDVTIEVTADRVRLRVHNGPGTRRGAGTGAGHGLVGMRERVALLGGDLHAGPDPDGGFT
                     VVADLPVAEPSASPSDPPARSAARPSETSMPAAVGPEYDGGSGSPG"
     gene            21988..22470
                     /locus_tag="Asera_RS01685"
                     /old_locus_tag="Asera_03410"
     CDS             21988..22470
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Asera_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Asera_03410"
                     /product="hypothetical protein"
                     /protein_id="WP_157035230.1"
                     /transl_table=11
                     /translation="METEQVPLPSPADAATALREVEQARRALDGTVPPWWYFVAMAALV
                     SVIPAAQLVPSGALGAVLGIAGFAGWTSLFVIVLRGYMHEVGFTVRLRRQKAWRLAVSG
                     IGSGLAMAVAMGLASSYDRWWIGFFGSGAISLAILAWAVPLRRAARRRQSGCVGAA"
     gene            22467..22793
                     /locus_tag="Asera_RS01690"
                     /old_locus_tag="Asera_03420"
     CDS             22467..22793
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014442956.1"
                     /locus_tag="Asera_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03420"
                     /product="transcriptional regulator"
                     /protein_id="WP_030449904.1"
                     /transl_table=11
                     /translation="MSVEPRFDATIHAPNRLRICALLDAVQSAEFATVQEKLDVSASVL
                     SKHVAVLVDAGYVQQRRATRNTRQRVWLSLTDAGRSAYQGHVAALRAIVAGGTEPSGES
                     AARH"
     gene            22918..23772
                     /locus_tag="Asera_RS01695"
                     /old_locus_tag="Asera_03430"
     CDS             22918..23772
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074697.1"
                     /locus_tag="Asera_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Asera_03430"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_084132926.1"
                     /transl_table=11
                     /translation="MTFDVRAGELFGFVGSNGAGKTTTMRIVLGVLAADSGQVRWDAEP
                     ITADTRRRIGYMPEERGLYPKMKVGEQLTYLAELHGMPRGVAQTAALQWAEELGIAGRF
                     GDEVQKLSLGNQQRVQLAAALVHDPGILVLDEPFSGLDPVAVDVMSEVLRRKAQQGIPV
                     VFSSHQLDLVERLCDRVGIVRSGQMVACGPVDELRDTGTARLSVLAPDAPAGWADGLPG
                     VTVLDQQHGRTTLSLATGADDQAVLAAALATGPVHEFARQRPSLTELFRNVVSAPTAEE
                     AAS"
     misc_feature    23890..23904
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    complement(23937..23951)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 gctggtcgac gcgctcgagg cgctgggcca cgccgacgac acgaacctgt gggtggcttc
       61 cgaccacggc agctcgccga tgaccggccg ggtcaatctg gccgaggaac tggccgcggc
      121 cgggttcggt cgcggcatct cctgctgcga cgacggtacg tccgcgatct ggctggacga
      181 cccggccgac ccggtggccg aacggctggt ggcctggctg cgccggcaac cgtggaccgg
      241 ggtgctgttc ggcgcggacg ggctgccgga caccgtgccg ctgtcgctga tcggtgcggt
      301 cgggccgcgc tcgccacagc tgttcgtcgg ctacgcgccc ggctggtact cggcgcaggc
      361 cggtccgacc accgacgcgc ccgactggca cggctgccac ggcagcgggt accggcggga
      421 cgtgcacagc gtgctacagg tgaccgggcc ggactaccgg tccgacgtcg atctgaccgc
      481 gccggccggg ctgatcgacg tgctgccgac gatcgccgcc gggctcggca tcgacgccga
      541 cttcgacggc cgggtactga ccgaggcccg cccgggcggg ccggcgccgg cggcgacgac
      601 gacccggctg gcgctgcccg gcgcccgcgc caccgtcaac cgcgtcgccg gggtgtccta
      661 tgtggacgag atagtgccgg accgctgacc cacccgggcg ggggcccgcg ccgggccccc
      721 gcccgacgcg atcgcctggc tcgacatggc caccgccgct cgacatggcc accgccgctc
      781 gacatggcca ccgccgctcg acatggccac cgccgctcga catggccacc gccgctcgac
      841 atggccaccg ccgctcgaca tggccaccgc cgctcgacat ggccaccgcc gctcgacatg
      901 gccaccgccg ctcgacatgg ccaccgccgc tcgacatggc caccgccgct cgacatggcc
      961 accgccgctc gacatggcca ccacccgtcg acgcgcccgc ctccaccggc acggtccggg
     1021 cacgggccgt cagcgccgtt acggcgcgtg tggccgccgg cggtcggctc ctccggtcag
     1081 cggtagcggc gctggtcgag cagatcgggg atgcggctgt cggccagacg gccggcgtgc
     1141 agctgccaga cgccggtcgg ccggccgtcc tcgttcacga tgtcgtcgac tcgctcgaac
     1201 cccagcgccc gcggtaccgc cgcgctcgcc gcgttcgccg gctcgtggtg gatctcgatc
     1261 aggtcgatgc ccgggacggc gaggccggcg gcggcgagcg cggcggcggc gcggcgggcc
     1321 accccgcggc cggtgtgccg ggagtcgacc cagtaaccga cctccagtgc gcccggcccg
     1381 acccgcgcca tcaggctggc gccgccgacc acgtcgccgc cccgcacgat cgcgtagttg
     1441 aacgcctggc tctcgtccca ctgctgccgc ccctggtcga ggaaggcccg cgcctcggtg
     1501 gcgccgtacc cctcgaccgc ccagggcatc cagcgggaca gctccggcat cgaggcctgc
     1561 acggcccgca ctatcgcgcg cacatcgccg gaacgccacc gccgcagcag cagtcccggt
     1621 gcggtcaggg tctcggaggg cggaacgagc cgtacagcca tggcgacatc ctgacagacc
     1681 ccgccaaccc ccggccccga ccgcgtcgat cagggtgtgg agtcacgcga aagcgctgtc
     1741 cggccgcttc acctcgtgcg cgagccggcc gcgggtgccg acgtaggctg gggcgcgtgc
     1801 ctgaaccact tgccgccgcg ctcgccgacc ttcgtaccct gctgaccgac tccgaccggt
     1861 tggtacgggc ggtcgccgcc ggccgccgcc ggggcgtgac gccggaggtg ccgcgggtcg
     1921 agctgcggcc ggtgcggatc ggggccggcc cccggctgca gatcgtcgag caggacgccg
     1981 cccgcccgcg cacccgcaac gtggcctggg gtgccgacgc cgaggcggcg gtggccgagc
     2041 tgctcgcccg gccgtacggg aactggcacg tcacgggcac cgatgccacc gtgcagctgc
     2101 gggtcaccaa gcggggcgag gcgcaggtgc accggtcggc cggggccggc acgccggccg
     2161 acaccgagca cgaccgcgcg aagagctacc tgctgccgcc ggatgacgag ctgtacggcg
     2221 tgatcggcgg caacgcggcc aagcgccgcc aggtcgacgc gttcctgcgg gcgctggacg
     2281 cgaccctgcc ggcgcagctg cccgagccgc tccgggtggt ggatctgggc tgcggcaacg
     2341 cctacctgag cttcgccgcg taccgctacc tgaccgaccg gcgcggtgcg cacgtgcaac
     2401 tgaccggagt ggacatccgg gccgaccagc gagaccggaa caccgcgctg gcggatcggc
     2461 tcggttgggc ggatcgcgtg tcgttcgtcg ccggcacgat cgccgccgca ccggtcgacg
     2521 gggccgatgt cgtgctcgcc ctgcacgcct gcgacaccgc caccgacgac gcgctggcgc
     2581 gggcggtgcg ctggcaggcg ccgtacgtgc tggccgcgcc gtgctgccat cacgagctgt
     2641 ccggccagct gcgcgaccgc accgatccgt tgctgcgcag cgcgatcctg cgggaacggt
     2701 tcgccgacgt gctgaccgac gcgatgcgcg ccgagctgct gcgcgcgctg ggctggtcgg
     2761 tggaggtggt ggagttcgtc gactccgcgc acactccgcg caacgtgctg ctgcgcggca
     2821 cgcgcggcgg cgtggacacc gccgccgcgc gtaccggcta tcagaccctg tcggacacct
     2881 ggcgggtcag ccccgcgctg gggcggcagc tcgccgatct gctgtcctga ccgccaggcc
     2941 cggccggtcg gcggcgcgga accggaacag gcgcagcgag ttcgacacca cgaacacgct
     3001 ggagaacgcc atcgccgcgg ccgccagtac cggggtgacc aggcccagcg cggccagcgg
     3061 gattgccgcc acgttgtacc cgaacgccca gaacaggttg ccctggatgg tgcgcagggt
     3121 gcgccgggac agccggatcg cgtccgctgc ggcgcgcagg tccccggcga ccagggtcag
     3181 gtcgctcgcc tcgatcgcca cgtcggtacc ggtacccatc gcgatgccga gatcggcggt
     3241 ggcgagcgcg gcggcgtcgt tgatgccgtc gccgaccatc gccaccaccc ggccggaccg
     3301 ctgcagttcg gcgaccacgt cggccttccc ggccggcagt acgccggcgt gcacctcgtc
     3361 gatgcccacc gcggcggcga ccgtgcgggc ggcggcctcg tggtcgccgg tcagcaacac
     3421 cggccgcagc cccagcccgc gcagcgcggc gaccgcctcg gcggcaccgt cggcgacggt
     3481 gtcggagacg accagcacgc cgcgggcggc gctgtcccag ccggccagta ccgcggtggc
     3541 accgtgcgcg cccgcggtcg tgatcgccgc ggtgagctct gccggaaccg tcaggccctc
     3601 ccgggtcagc aactccggcc ggcccaccac gacccgccgg ccgtccacgg tggccagcgc
     3661 accgaacccg gccacggcgg cgaagtcggc cacctcgggc agcggccccg ctgcggccgc
     3721 ggcgctcgcc acggcgcggg cgatcgggtg ttcgctggcg tgctcgaccg cccccgcgta
     3781 ccgcaggatc tcggccggcg actcgccagc ggcggcgatc gtgtcggtgt gcgtcatccg
     3841 gccggtggtg accgtaccgg tcttgtccag caccacggtg tcgatccgcc gggtcgactc
     3901 cagcacctcc ggccccttga tcaggatgcc gagctgagca ccgcgcccgg taccgaccag
     3961 cagcgccgtc ggtgtcgcca gcccgagcgc gcaggggcag gccacgatca gtaccgccac
     4021 cgctgcggtg accgccgccg cggccggccg cccggtggcg agccacgcca ccagcgtgcc
     4081 gagcgcgatc accagcaccg ccggcacgaa caccgcggag atccggtccg ccagccgctg
     4141 tacctgcgcc ttgccgttct gcgcgtccgc gaccagccgg ccgagctgcg ccagctgggt
     4201 gtcggcgccg acccggcggg cggtgacgac gaggcgcccg cccgcgttca ccgtcgcacc
     4261 gacgacctcg tcgccgggtc cgacctcgac cggtaccgac tcgccggtca gcatcgacgc
     4321 atccaccgca ctggtaccgg actcgacgac gccgtcggtg gcgatcttct cccccggccg
     4381 gaccacgaac cggtcgccga ccgacaactg tccgatgggg acggttcgtt cccggccgtc
     4441 ggcggccagc acggtgacgt ccttggcacc cagggagagc agcgcccgca acgcggaccc
     4501 ggcccgccgc ttggcccgcg cctcgaagta ccggccggcc agcaggaagg tggtcagcgc
     4561 ggcgccgacc tccaggtaca gctggggtcc ggtgtcggag ccggcgaaca ggtgcaggct
     4621 catccgcatg ttctcgccgc ccgcgccgcc gaggaacagc gcccacaggc tccacaggta
     4681 cgacacggtc gcgcccagcg agaccagcgt gtccatggtg gcagcgccgt gccgcaggtt
     4741 ggtcagggcc gcgcgatgga acggcccggc gccccacacc acgaccggtg aggtgagcgt
     4801 cagcgcgagc cactgccagt ggttgaactg cagcggcggc accatcgcga gcagcagcac
     4861 cggcagcgtg agcacggccg agccgagcag cctggtacgc agcgagtgtt cggccgcgtc
     4921 ccgctcgtcg gcgaccggtt cgtcggccgc cggcgccggc ggttccggcg gctgcgcggt
     4981 gtagccggtc gcttcgacgg tgccgatcag atcctgcacc gtggtaccgg ccgggtagtg
     5041 cacccgggcg gtctcggtgg cgaagttgac ggtcgcggcc acgccgggca gcttgttcag
     5101 cttgcgctcg acccgggccg cgcaggacgc gcaggtcatg ccgccgatcc gcagctcgac
     5161 tgcgggaccg ttactgtcca cagtagacat ctaccctccc cgatcggtgc ggtggcgccg
     5221 gccgcgctca ggccagctgg tagccggcct cgtcgaccgc ggcggccacc gcgtcggtgg
     5281 ccagcggctg gttcgcgtcg acctcgaccc ggccgctcgc cacgtcgacc cgaaccgcct
     5341 ccacgccggg cagcccgcga agctcggtgc tcacggcgct ggcgcagtgg ccgcaggtca
     5401 tcccggtgac ggtgtatgtc tgagttgcca tggttgcctc cacaacggtg aacgtgcgtc
     5461 aggatcggac caaccgggcg attgccgcgg tggcctcctt gaccttctct tctgcctctt
     5521 cgccaccttt tgctgtggcc tcggccacgc aatgtgacag gtgaccgtcg agcaggccga
     5581 gcgcgacacc ctgcagagcg cgggtcgcgg ccgagatctg ggtgaggacg tcgatgcagt
     5641 acgtgtcctg ctcgaccatc cgctccaggc cacggatctg cccctcgatc cgccgcaacc
     5701 gagccaacag tgccgtcttg tcgtcgctgt accagtaacc cgccatgtgg ccacctcccc
     5761 cgttcggcct cacagtacca taccccccta ccgtatccaa ccacggagcg gagcgacctg
     5821 gatgcgaacg gatcaattcc cgaaacaatg tgagtggcac gccgggggcg acttgcgatc
     5881 gactgacggt tactcctaat gtgactcccc gtctgaccgg atgtctgccg cctgcccgtg
     5941 ggcggcaccg ggcgacaccg ccgagttgcc gcgcgagccg cctcccctgg cgctggccgg
     6001 cgagccgggg acccactccc tggggtgagt ccacgacctc cgggtcgtgg tagggcgcac
     6061 ttcttccccg cccgaacccg tcagctaacc cggtaggcgg tgcgaggaag aaggagccgg
     6121 ctgccggtgc ccacctccgc tgtcatggcg cgaccgctgc gggccttcgg cctgctgctg
     6181 ctggccgcgc tcaccgcgat ggccctgttg ctgctcggta ccccggcgca cgcgacaccg
     6241 tccgaggccg agctgaccaa gcagatcgac gccaagtcca agcagttcga caaggccgtc
     6301 caggagtacg acaaggtcca ggaccagttg acctccagca agaagaagga aaaggcggtc
     6361 aacaagaagc tcaagccgct gcagaagaag gtcgacgcgg cggagcaggc ggtcggcaag
     6421 atggccgccg ccgcgtaccg cgggggcaag cccggagcgg tcaacgccat cctctccgac
     6481 ggctccgcca gtaccctgct cgactcgctc tcgctgctcg accagctggc gcgcaaccag
     6541 agcaagcaga tcgccgagtt cagcaaggcg aaggccgcgc tggacaagca gaaggcggcg
     6601 ctggacaccg cgatcggcaa gcagacgcag gcgaagcaga agctcgccga ccagaagaag
     6661 tcgctcgaca aggacgtgca gaagctgcgc gacctgcgca cccaggcgta cgggtcgccc
     6721 acgaactacg acaccaacgt cgactacggc ccggcgccga acctgcccgg cagcgccggc
     6781 aaggcggtcg actacgcgtg ggcgcagctc ggcaagccgt acaacatggg ttccgcgggg
     6841 cccgacgcgt tcgactgctc cggcctgacc atgatggcct ggaacgccgc cgggtactcg
     6901 ctcgcgcaca gctcgtacac ccagtacagc cagacgcacc ggatcagccg ggaccagctg
     6961 caggccggtg acctggtgtt ctacagcggg aacgagcacg tcgcgatcta catcggcggc
     7021 ggtcaggtga tccacgcacc gacctacggc gagccggtgc agaaggccag cgtcgacatg
     7081 atgccgccgg acggctacgg ccgggtcggc tgagcagaca agccttaccc ccacccccac
     7141 gcgacgccgg taccggagcc tcccccgtct ccggcaccgg cgtcgcggtc tgtgccgcgc
     7201 cgtggccact ggcccggcga cggcgaggac cgccagccag gatctcgctg tgacccgccc
     7261 gtaccggacc ggtaagctcg atgcgggccc gcggggcatg gcaggggcac gcggcgacag
     7321 ccgggagccc cggatcgccc caggacccca cggatggccg gttcagcagc cacaacgccg
     7381 gccgctgccc tcgtagctca ggggatagag caccgctctc ctaaagcggg tgtcgcaggt
     7441 tcgaatcctg ccgggggcac aacacgacat cgcccggtgc gcccagcgca gcggtgcggc
     7501 acccggcggg gtcaggaacc cgaccggccg cgcggcgccc gtcactcccg agccgggcga
     7561 gacgtgtcca ggcggtcact tggtggcgag gacctcgcgg agtcggcggg cgaaggcctc
     7621 gggctggccg gcgtagccgt gctccccgcc gacgaatccg ccgtgatggc tcgggaagac
     7681 cgtcgcctcc tggccgagca gcgcggcggt cgccgtcgcg gtacgggcgg tgaaggtgcc
     7741 ggcggactcc tcgccgacgg cgatgatcac ccgggtcggc gccgcggtca gcgccgcgac
     7801 gtccggccgg tagtcggtga tcgccagcgc acggtcggac agcagcgggt cgtcgcggtt
     7861 gccgtcgtcc tcggtgggca tcccgtacgc ggccgggtcc ggtgccggct gggcgaagta
     7921 ctcgtcggtg aactcacccc gccacgaggt catcgcgacg aacgcggcca tcccggcacc
     7981 ccaccccttc gcctggtacg cggcgaggaa gccgtcccgc gcgcggaccg ccgcggcggc
     8041 gtcgggcagc accgggagca tcggcggttc gtgcgcgacc agcgtggcca cgtcgttcgg
     8101 gtacgcggcg accagcgcca gcgcggtcac cgcgccgccg ctgctggcga acagctcgac
     8161 cgggccggcg tcgagcgccc cgatcagcgc gtgcacgtcc gccgcctggg tctgcggggt
     8221 ctggtcgacc cgcccgtccg agcgggtgct gcggccgagg ccgcgcgggt cgtaggtgat
     8281 cacggtgcgg tccgggaact gcgccaccag cgcggtgaac ccggaggcgt ccatcggttg
     8341 gccgatcatc accagcggcg gcgtgccgtc ggcggtcggc agcggtccgt gcacgtcgta
     8401 ggtgatctcg gcgccatcgg tgggcactac gcgtgtcgtc gtcataccgg taccgacggc
     8461 ggcgccggaa agaactcatc ggcgccggcg cagcccggcc acatccggtt cgtcgcggac
     8521 cgatgattcc cgcgcggcgg cgccgtcggt actggcgacg gtcggtgccg gcacggggcg
     8581 gcgccgaccc ctttcgacgg gagacggtgt ggacgaggtg gtgatcggcg cggcgccgcg
     8641 gcccgagccg gtactggccg ggtcgtggct gacggtgctc ggtgggatgc tggacttcca
     8701 ccgggcgacg ctggtgtgga agtgcagcgg gctgaccgac gccgagctgc ggcggcgacc
     8761 gctgcgctcg gagctgagcc tgctcgggct gctgcgccac ctgcagggcg cggagcggta
     8821 ctggttcggg gttcggatcg gcggcacgac gccggcgttc cacccgtacc ggatgtaccg
     8881 gaccgcgcag ggtgagcaat ggtacgacga ggcggacccg acgccggcga gcgaggtgta
     8941 cgcggactat ctcgccgcct gtgccgagtc acgcgcggtc caccggcgcc tcggcgaggc
     9001 cgacctcgat cggctcgtcg acaacgacga gttcgggccg gcgagcgtcc ggttcgtact
     9061 gctgcacctg gtggaggagt acgcgcgcca cgtcggccac gccgacctgc tgcgcgagac
     9121 gatcgacggc accacgggcg agtgattcgg tcgcgggcgg ccccagacgc gcgggtacgt
     9181 cggtcacccg cgacccgcgg tctcggcacg acgggcgagg gcgtcagtcg cgggcggccc
     9241 gcggctccgg tacgacgggg ccggggggca cggcggcggc gccgccggtc caccggctgc
     9301 gggcgagcag ccggtcgagg ccggcgaagg caccgagcag cacgaggccg agcagtacca
     9361 cgaacgccag gttgcgcacc gtcgcggcgt agccgaggtc cgtgacgttc aggaacgggt
     9421 acgggtacca gccgctcgcc gcgccgtgcg cgagggtgta gccgatccac agcagcggcc
     9481 agaccagcgc gcagccgagc gaggcgaggt cgatccgccg gcgcgggccg aacagcaacc
     9541 agccgaccac cgcgatcggc ggcgccgcgt agtggaacat caggttgagc caccaggcca
     9601 gcccggtcgg atggctgtca ccggccagga ccagcgcgaa caccaggccg gtgacggtga
     9661 tgccgagcag cgcgtcgagc cgcagcaccc ggcgcagcct cccgtcggcg gccggccgta
     9721 ccgcccggac ggcgcagtcg gcgagcacca ggatgttgct ctggatggtg aagaagctga
     9781 acgtgcggac cagccgggcc gcgaccgaca cgccggggtc accgtccccg ccggtgcaga
     9841 cgaggacgac ctgcgcgacg agcgcggcgc cgatcagtac ggcgagtacg ccgtgccagg
     9901 cgcgcccgac ccggtggagc gcacgctcgg tgtccatggc gcctgacgct accggccgcg
     9961 cgcccgtccg taccggtccg acaccgctgc ggttgggtgg tcagcgccgg gcggtcgcgg
    10021 cgagccagcc cgcggtggcc cgaaccatcc ccgggatcgg cgtaccggcg aggattctcg
    10081 cctcgtcccg ccgggtggac gtgccgtcca ggaagccgag gatccggtcc ggtgggtgtc
    10141 gggtcagcaa ctcggtgaac agtcgcgggc cgtccaccag gccgcggtcg atcgcccgca
    10201 gcaggatcgc gtcgtaccgc aggtgccgcg ccgggtacgg gcgcggcggc accgggtcgg
    10261 ccccggcggc gagccgggcc gcgaccaccc gcgcctgccg cagcatggtg gcgaacgtgt
    10321 agccggtggc cggccgggtc gcgccaccgg cggtacccag ccggtacacg tgcggtgcga
    10381 cccggcgggc gaaccggccg tcggtcatcg ggatgacgcc gtcctcgatg gactccacga
    10441 tcgcgccggc gacgccgagc cggtcgcaca gccggtccag cgccgcatcg tagtccgcgg
    10501 gcgcgagccg ggaccgggag aacaccgtgt actccaccag cgcctcgtgc cggtcgaccg
    10561 gcagcacgta gccgaacgcg agcccggact ccggctgcgg cacggtgaag tccatcagcg
    10621 tggccgcggc cgggtcgagc ccggcgccgg acagccagcg accgcggaag tgctgcagca
    10681 gcgtcgtggt gcccggccgg tccggtggtc gcggacgcga gtcgaacacc cagcgcgcgg
    10741 tcacctggcc ggcgtcggtg tccaggacca ccccgccggt gtccggcccg tcctgcccga
    10801 ccaggccgac gggctggccc gacggagccg gctggcccgg ctggcccggc ggcgccagct
    10861 ggcccggcgg agccggcgca acggtctcgc ccggccggtt cccgccctcg cccggcccgg
    10921 ccggcggatc cgcgcgcgcc ggccggatcg cgcggaccga ggccggcatc cagcgcacgg
    10981 ccgggccggc cgctccggca gcgcccgccg cgggcggcgc acaccgctgc cgcacctccc
    11041 ggtagaagtc cgccgagcgg accatcgcgt acgagaccgg cgccagctcg cgcgcaccgc
    11101 cgtccgggcc gaccacccgc agcctcgacc accgccggcg caccgccggc tcgaccgggc
    11161 tggtaccgcc gtcccagaag caccaggtgc gatcgttccc ggtgtgcgac accggatcca
    11221 gcaccgccac cgacacccgg acgccggccg cggcgagcgc gtgcagcagg cagtgcgccg
    11281 ctccgccgcc gccgaccagc gcgacgtcga cgtcggtgcc gtgcccgctg gtcatggccg
    11341 ggacggtacc gggccggtga tgcgctcggc ggcgagccgg ccggagacca gtaccatcgg
    11401 caccccgacg ccgggctggg tgccggagcc gacgaagacc acattggaca gtccgggcgc
    11461 ccggttgccc ggccgcagcg gcccggtctg gccgaacgtg tgcgccgccg cgaacggggt
    11521 accggcagcc atccccgccg cggcccagtc cgccggggtc accagcaccc gctcggtcac
    11581 cgcggcggac agcccgacgt accctctcga ctccgccgtg gacagcagct cctcggcgta
    11641 ccgcgggccg aactccgccc agtcgatcgg tcgccggtgg gccaggttcg gggtgggcgc
    11701 gaggaggtag tacgtgtggt gcccgggcgg cgcgagcgac gggtcggtcc ggctcgggtt
    11761 ggtgatcagc agcgacgggt cgcgcatcgg caccccgcgg tcgatcacgt cgtcgaacac
    11821 cggccgccac gaccgtccga agtggacgtt gtggtgcgcg atcccgcgat acgacgcgct
    11881 cgcgccgagg tgcagcagca cgcaggacgg cgagtaccgc aaccggcgcg gccggcggcc
    11941 gagcaggtcc cggtacgcca ccggcaggtc cgggttgagc accacggcgt cggcggcgaa
    12001 ccgctgcccg cccgccgtcg tgaccccggt ggcccggtcg ccgcgccgct cgatcccggt
    12061 cacctcggtg ccgtaccgga tgtccacgcc gtgcttggcg gccacgtcgg ccatcgcctg
    12121 cgcgaccgcg gcgattccgc cgcgcgggaa gtacaccccg gcgatcgtgt ccaggtacga
    12181 gatgaccgcg tagagcgcga gcgcccggtg cggcgcgacc ccggcgtaca gcgactggaa
    12241 cgagaagatc cggcgggtac gcgggtcgcg gaagaactgg ccgatcttcg cgtccaggct
    12301 gcggaagccg cccgcggcgg cgagccggac caggttcggc gtcagcagct cggtcggccg
    12361 gtcgaagttg cggtcgatga agtcgtgcca ctcgatccgg tacaggtgcc gcgcgtagtc
    12421 gacgaagcgc aggtacccgt cggcctcccg gggaccgcac agcgcggcga tctcgccggc
    12481 catcgcggcg gtgtcggtcc gcacgtccaa cgtggagccg tccggaaagt gcgcgcggta
    12541 ggccggatcc agccgggtca gcgtcaacca gtcggccagc tcctcgccga ccgcggcgag
    12601 cgtgtcgccg atcagctgcg gtacggtcag caccgtcggc ccggcgtcga accggaaacc
    12661 gttgcggcgc aacagtcctg cccggccgcc aggcctctcg tcgcgctcca gcagggtcac
    12721 cgcgcggccc gcgccggcca gccggatcgc cgcggcgaga ccgccgagcc cggccccgac
    12781 gaccaccacc cggtcgaccc gccccggtac ggtcttcacg ggccaccccg gcggcgcggt
    12841 gcgaggcctg ccggcccggc accgcagcgg gaggcaccgg gaccacaacg gctgggctcg
    12901 gccggcaccg tccgcggcga ccggctcgca ggacggcggg tggcgttcat gcgaggcgct
    12961 ggacgcacgc gagcgcgagc gcgctcagcc ggtcccgggc caccgggtcg atcggcgcgg
    13021 ccgcgagcgc ggccagcccg gccgacaccc gggcggagat catcgtctcc gcctcggccc
    13081 gcgcaccgga ttcggtgatc gcggcggccg catcggcgat cgccgcatcg gaggcgtccg
    13141 ggtcgccgta cacccggtcc agcctccggt gctgggccgg cgcggcgagc gagaaggcca
    13201 gctcggcgag caccgtcggc ttgccctgcc gcaggtcggc gccgaccggc ttgccggtca
    13261 ccgcgctctc gccgtacacc ccgagcaggt cgtcgcgcag ctggaacgcc tcgcccaccg
    13321 caccgccgaa ccggtcgtac gcggcgacca cgtccggcgg caccgcaccg gacagcgcgg
    13381 cgccgaactg cagcggccgc tgcaccgtgt acgacgcgga cttgaaccgg gccacctgta
    13441 ccgcggtgcc gaccccgggc gcgccatccg cgccgtgcag aacgtccaga tactgcccgg
    13501 cgaccgcctc gatgcgcatc tcgtcgtact cgcgccgcgc gcccagcagc accgccgccg
    13561 gcaccccgga ggtaccgatc agccgatcgg cccagaccgt gcacaggtcg ccgagcagca
    13621 ccgccaccga gtcaccgaac ctcgccgggt cgccgcgcca gccggccgcc acgtgccgtt
    13681 cgccgaactg gcggtgcagc gtcggcgccc cccgccgggt tgccgcggcg tccatcacgt
    13741 cgtcgtggat cagcgcgaac gcgtgcagca gctccagcgc gctcaccgcc cgcagcaccg
    13801 cctcgtcggc gccggtggca accccgcggt acccccagta gccgaacgcc ggccgaaggc
    13861 gcttgccgcc gccgaggatc agctcgcgca gcggcgccgc ggcggccgcc acctcgggtg
    13921 acagcgatcg aagggtggcg atctcggcgg tgacgaactc gtccagcacc gcgtctaccc
    13981 gcgcggcgat cccggcggcg ctggctccgg tagccccggg gccggcggca cgggatcggg
    14041 tggcgccgct gcgggcgccg gggtgcgcag ccacgactcg agcctaccca gccgtacgcc
    14101 cacgccccgc gcctggttgg gtaggggtcg gcctcgccac cccgcgaccc ggcccgccgg
    14161 gccggaccgg cgcccgggtg gcccgactcg gtagaaggat gcgcgcatgt tcgactccac
    14221 cccgaccgtg ctcggtcacc gcggcctggg caagggcatc gtcgacggac tgaccgagaa
    14281 caccatggcc tcgtaccggg ccgcgatcga gctcaccgac tggctggaac tggacgtgca
    14341 gcgctgcgcg gacgacgagc tgatggtcta ccacaatccg gccaccccgg acggggtgtt
    14401 cgtgctggag cagaccgccg ccgaactggc cgccaagggc gtgctgcggt tcgccgacgt
    14461 gctcgccgag ctgcccaccg aggtcggcct cgacatcgac gtgaagacgc cgatcgagga
    14521 cgcgatcgcc gcgccggacc ggcgcaccgc ggcgctgctc gccccggtac tcgcggccga
    14581 gctgtcccgc cgccggctgt tcgccaccgc gttcgacccg gcgctgctgg tcgagctgaa
    14641 ggaggcggta ccggggctgc cgacctgcct ggtgcactgg ctggcgtacc cgctcgggcc
    14701 ggcgatcgcc gcggcggccg gcctcggcgc gagcatcgtc gggctgcaca ccgactcgtt
    14761 cggcccgagc ccgctgcaac cggacccggc catccagtac gaccacgcct acgcggtcga
    14821 ggtcgcgcac cgcgcgggcc tggaggtact gacctggtgc ccgtccgccg accgcgcgcc
    14881 ggcgctggcc aaggccggcg tggacgcgct gtgcgtgaac gacatccccg gcgtgcaggc
    14941 cgcgctgcgc tgaccgcccg ttccgcgtcc ggctgacgcc ccgggtaggc cggagcccgg
    15001 ccccgacacc cctgagtgag gaatccccgc atgaccgaga tgtccgtaca gctggaacag
    15061 atcgccgtcc gggcggcgcg cggcgtcggt gacgcgctgc gggccgcgtt cgtgcaggcc
    15121 cagcagccca gccacaagcg ggaccaccac gacctggtca ccgagcacga cgagcgcacc
    15181 gagcaggtgc tgcgggccga gctgctcgac gcctggcccg actccgcggt actcggcgag
    15241 gagggcggcg cgagcggcga cggcgcggtg cactggctgg tcgacccgat cgacggcacc
    15301 gccaacttcg ccctcgggct gccgttcttc gccgtgtcca tcggcgcggt ggcgaacgac
    15361 cagctggtcg ccggcgtcgt ctacgacgtg atgcgcgaca ccgcgttctc ggcgaacctg
    15421 cacggcgcgt acgccgacgg cgagccgctg cggtccaccg gcccggcgac cgacgcgcag
    15481 aacatgctga tcacctcgta cccggggccc ggcacgctgg ccgccggccg cggcgtcgag
    15541 gaatacacca cgctgctgcg cgagttcggc gcggtccggc ggatgggctc caccgcgctc
    15601 gccctcgcgt acgtggcggc cggcgccggc tgcgcctacg cgtacgggat ccacccgtgg
    15661 gacgtggcgg ccggcgcgct gatcgtgcag caggccggcg ggcggtacct gccgctgccg
    15721 gacaccgggc ggccgtggga ggcacccggg tacctcgccg tgaacggcga cttcgacctg
    15781 cccggctcct gcctgaccga cctgctgccc cggatgctcc cgcgcaccgc caccggcacc
    15841 ccgctgcccg gcggggggct ccgaaacaga ccctagcccc ggtcgccgac cgtggagtcg
    15901 tcggtcgcgg ggccgtcgcc gaccgtggag tcgtcggtcg cagggccgtc gccggtttcg
    15961 ggcgcgtccg cgcgatcgtc gtcggcgacc gggcgcagca gcggggcgag ccggacgatc
    16021 atctggtcca gcagctcggc gagatccggc tcgccgtggt ggtcggtcca gtaccgaagg
    16081 gtctcggtca ccgccgccgc gtagccggcg accgcgagcc gcaccgggta ggagtcgggt
    16141 tcggcgtgca gccaccgggc cagcagctcc tcggcctgcc cgcggccctg ctgctgccgg
    16201 tgctggaacg ccgcccacag ctccggcacc gaaaagatca gcgagtaccg ggccagcatc
    16261 tcgtcccggt cgaacgccat gctccccatc gccctgcgca ccatcgaccg cagcgcggcg
    16321 gtgatgtcgg tggcctcgcc cagctcggcg aacaggtcgt cggcgccgtc cggcggctcg
    16381 tactcgccgg agagcaccac gtcgaccatg gacgagtagt accggtagaa ggtcgtggtc
    16441 gagatctcgg ccgcctcggc gatctgctcg accgtcgtcg cggcgtagcc ctgctcggcg
    16501 aacagccgga acgcctcccg ctgcaccgac tgccgcagct tgtacttctt cttctcccgc
    16561 agccctgcca cgctcaccat gctctcagcc cgcccgcccc cgcgggccgg cgctctcggc
    16621 ccacctcgcc gggtggggct cccggcacac ccgccgccgc gggccggggc tgccggccca
    16681 cctcggcggc gggggccctc agcgggtgcc gacctcggcg ggtgcggtgt agtcgggcag
    16741 ggtcagcgac gacttgacct tggccacccg gccgccgaac gcgccgagtc gcagcagcag
    16801 cggggcgacc cggaacagct ggttgcgggc ccacacgccg cgccgggtcg cgggcgcgac
    16861 ggccaccccg ccgccgccga tcgcgagcgc ctggttgtcc gcgacgaact gccgcatccg
    16921 ctgctcgtac gccgcgaacg cggcccggtg gtcggtggtc gcggccagct cgccggccag
    16981 cacgtacgct ccgaccaggg caatgctcga accctgcccg gacaggaacg acggcgcgta
    17041 ggccgcatcg ccgaccagcg cgacccgacc gcgggaccag ttcggcatcc ggatctggct
    17101 gaccacgtcg aagaacaggt cgtcggcggt gcgcatcgcg tcgatcatcc ggggcacctc
    17161 ccacccgccg tcggcgaaca ccgacgcgac gagctcacgc tgcgcggccg ggtcgcggaa
    17221 cgcggcgaac ggcgcctcgg cccggccgaa gctgaggaac ccgtgcaccc ggtccgggtc
    17281 accggcggcg tagagcaccg cggtccggcc cggcgcggtg ctcgccaccc cctcgtggtc
    17341 cagccccagg tggttcggca tgctgaagcc cgcgaagcag tgccccaggt agtggtggaa
    17401 ctgctcctcc ggcccgaaca ccagccgccg ggtgttggag tgcagcccgt ccgcgcccac
    17461 caccacgtcg taccgggcgg tgtccccgcc ggcgaaccgc acgtcgacgc cgctgtcgtg
    17521 gtcggtcagc tccgcgatcg agtcgccgaa ccggaactcg acgtcgtcgc cgatcgcgtc
    17581 ggacagcagc ccggtcagcg cgccgcgggg cagctcggtg tcgccgccgt ccgcgccgcc
    17641 cagccggtcc agccgcagcg acacgacccg ccggccgtcg tcgcgcagga acgtcatccg
    17701 ccccatgtgc aggtgcgcgg cccgcagctg ctcgtaccgc cccatccggc ggatcacgtc
    17761 cagcgcggtg ccgcgcacgt cgaccgggta cccgccgccg cgcaccgctg ccgccttctc
    17821 caccacggtc acctcgaacc cgtaccggtg cagccagtac gcgagcgccg ggccggcgat
    17881 gctcgccccc gacaccagtg ccgtcctcgt catcgcactc tcccctcacc cggccggcgt
    17941 atcaggtcac cagccctttc gggttactgt actactttgg ccatcgaccc gtttatgcac
    18001 agcgtcgggg caggtgcgaa tccggacatt cactccagtc gggccagccg ggccgtctcg
    18061 acccgtggcc cggtcggatc gcctccgacc cctcggactg gccgccgctg gttcccggac
    18121 cccgccgggc aggccgtcag gcgggcggta cggcgtgcgg ccggcgggcg gcgtgcgtct
    18181 cgacgcggcg gaacagcagg cagaagccgg cgaggaccgc cccgaacgcc ggggtccaga
    18241 gcagccgcag cgccagccag tcaccggcgg gcgggctcag cagccccggt acctggccga
    18301 acggcagccc ggcgagactg accgcgagca gcgcgctctg gtgccagcag aagacggtca
    18361 tcgcggccag gttgagcacc gcgatcggcg cccacgccgc cggccggcgc agcagcgccg
    18421 ccagccgacc tcgtaccagc aggaacgcgc cgagctgcgc ggcggccagg gccagggtga
    18481 acagcgacgg cggatccagg ttcgaccaac cgtcaccggg tacgccgacc gcgctcgccg
    18541 ggtacccggc ggcgacgagc gcggcgccgg ccacgacgcc ggccggcagc agcaccgcac
    18601 ccgcccggtg cggcagcgtg ccctcggcca gcccgatgcc cagggcgtac gggaccgccc
    18661 agcccaccgg tacggcggcg agcacgagcc agctcggcaa cccggccggc cgcatcgtgt
    18721 cgaccaaccc gatcgcgccc accagcggca ccaaccacca cagtccacat cgggcggtca
    18781 gggtgcgcag caccggcgtc gccgcggtga gtagcaggta gaccagcagg aaccagagcg
    18841 ggtgggacac cagcgaccag accacctggc gggtcggccc cggcaccccg agcgccggca
    18901 acgccgccag caccgggccg aacaccgcgg cgagcgccag caccggcagc accagccggc
    18961 gcagccggcc ggccagccac ggcagcgccg cccgaccgcg gctgccgcgc gccgccgcgt
    19021 acccgccggc gaagaagaac gggccgagca gttgcagcaa ccagctcacc ggcgccgccc
    19081 cgggccaccc ggacagcggg ctgtggttgg tcagcacgcc gggccggccg gggtcggcga
    19141 cgagcgcgga caccagccag tggccgatca ccacgccgag catcgccacc gcccgcaacg
    19201 cgtcgacggt acggtcccgc cgcaccggcg tggccgcgtc gacccggccc gcccagcggt
    19261 gccacgttcc cttcctgcca acggttgccg cgaccggcac gtcggtcgta ctcatgccgc
    19321 acctccgccg ctcgccgcga gcgccgtgcg ggccggggcg aagtgaccgg ggccgagcgc
    19381 gatgcgcgcc agcgcggcca acgagtccgt accgggggcc aggtagtggt cgtggtcgcc
    19441 gacgtctgcg gtcgggaaga tccgggcacc gaacgccggg tcggccggct tgcggccgtg
    19501 cccgaagccg aacagccgca gccccggcac gtaccggatc cagtccttcg tggactgtcc
    19561 ggcccagacc cgggccgggg tgtgcagcgc cgacgcggta cccacgccca cgcccgggct
    19621 gccgaacagg gcgatgtcgg tgacctgcct tggcaggtac cgggcggcga ggccgagcac
    19681 ggtggagccg tagctgtgcc ccagcagcgc gatcgtcgca tgtggacgga ccgcggtcag
    19741 tccggcgacg aaccggcgca acgccacggc accggtcgcg gccagccgtt cccgggccgc
    19801 gtcgatcccg accccgcgcg gcgtggcgta gccgagccag gcgatcacgg cgatgcgggc
    19861 gcccgacgcc cggtacaggt tcgccgcctg caccgcgggc gaccggtagg ccttgccgcc
    19921 caggccgcgg cgaaagttcg ccagccggtc gtcgaccccc gggaccagca ccgcgatccg
    19981 gtccgcggtg gacaggtcgc cgaacacctg cgcgaccctg ccgtcgccgc gcggatcgaa
    20041 cagcaggtac cgtccgtgcc agcccgcgta cggcgcgccc gccgcggcca tcgccgcccg
    20101 gttcgcctgg tagcgcagcg cgatcggcgc gccgtccagc tcaccgacca cccccgggta
    20161 ccgcgtcgcg agcgagcgcg gcgcgccggc cagcgcggcg tgcaccgccg ccggtgtcgc
    20221 ggtcgccggg tccggcaggt gccgcggatc cgcccgccac gccgcggtac cgatcggcac
    20281 cgcggcgggc ccggcggtcg ccggcccgtc cagtaccgcg ttcgcggccg gtgccgccac
    20341 cagtaccgcg ctgagcaccg ccagcgccca ccgacccagt cgagatcgca tcgcccgtcc
    20401 cttcgcctcc gggtcggcga gcgagcgcca gcctggcgtc gtcgccccca cccgtcgtca
    20461 ctgcggcgaa agttagggcc ggaaacgggc ccggcacgtc accccgggga gccggatccc
    20521 ccgtcatact ccggaccgac ggccgccggc atcgacgtct ctgagggccg ggcggctgac
    20581 cgggccggcg gatccgacgg agaggctgac ggttcggcga ccggcaggtc ggcgacgacg
    20641 gtgaagccgc cgtcggggtc gggcccggcg tgcaggtcac cgccgagcaa cgcgacccgt
    20701 tcccgcatcc cgaccaggcc gtgcccggca ccggtgccgg caccgcggcg ggtaccggga
    20761 ccgttgtgca cccgcagccg gacccggtcg gccgtgacct cgatcgtgac gtcgaccggt
    20821 gcgccggcgg catgccgggt cgcattcgac agcgcctcct gcaccagccg gtacgcgcac
    20881 acctgtaccg cggtgggcgg ccggtgctcc agtccctcgg cgcggtagga gatccgtacc
    20941 ccggcgcggc gaccaccggc caccagtccg tccacatcgg acagtccggg ttgcggtgcc
    21001 cgcagcgcgt cctcgtcgct gcgcagcacc ccgagcagcc ggcgcatctc gaccagcgcg
    21061 ctgcgggcct gcgcggcgat cgagtcgagt tcctcggcgg cgccgggtga gacgtcgtcc
    21121 cgccggtacg gcgcggtctg cgcctggacc acgatcaacg acatgtggtg tgccaccacg
    21181 tcgtgcagtt cccgggcgat ccgggtgcgc tcctccagcg cggcccggcg tgccttctcc
    21241 agttcggtgc gctcggtctc ggcgaccagc gcccgctggg cccgcaaccg cgaccggatc
    21301 aggtcgacca ggaccgcgcc gatggtcagt acggcgaggc cgccgggcgc gttgccggcg
    21361 tcgacgtgca ccaccagtac gccggccatc gccgcccaca tccaccacag caccgcccgc
    21421 tggtaccgca ggccggcgag aacgaacgcg accgcgagga tcgggatctg ggccggctcc
    21481 cacggccagg aaccccacac gggcgccgtg cggaccgccg gcgcgagcag ggccgcgagc
    21541 accccgatcc gccagcccat cagcgggtag cgcagcgcga gtaccagcgg cagcagttgc
    21601 accacggcaa ggatcaggac gatcgcgctc tgctcgccgc ggtgcgcgtt cagcaccgtg
    21661 accatcgtca ccgggtacag cacggcgatg gcggccacca cggcgatccg ggccgcccag
    21721 cgcagccagc ggccgcggcc gaccggccag cggatcgggg tgtccggccc gtagagcagc
    21781 tgccgcagcc cgcgccacgc cgctgcggtc acctgtcgcc accgttggtt ctgcaccacg
    21841 ccgacggtag gcgggccggg cgccccgcgt cgtgccgccc aggtgggacg ccgcacgtcc
    21901 cgcctgggta cggggtcggg cggccaggtt tccagcgcgg aaagttatga cttgacaggt
    21961 tggaaacgaa caccgagact ttccgacatg gaaacagagc aggtgccgct gcccagcccg
    22021 gccgacgccg ccaccgcgct gcgcgaggtc gagcaggcgc gccgcgcgct cgacggcacc
    22081 gtcccaccct ggtggtactt cgtcgccatg gcggcgctgg tctcggtcat tccggcggca
    22141 cagctggtgc cgtccggcgc gctcggcgcc gtgctcggga tcgccggctt cgccggatgg
    22201 acgagcctgt tcgtgatcgt gctccgcggg tacatgcacg aggtcggctt caccgtccgg
    22261 ctgcgccggc agaaggcctg gcgcctggcg gtctccggca tcggatccgg cctggcgatg
    22321 gccgtcgcga tgggcctcgc gtcgagctac gaccggtggt ggatcggctt cttcggctcc
    22381 ggcgcgatct cgctcgcgat cctggcctgg gcggtgccgc tgcgacgggc cgcgcgccgc
    22441 cggcagagcg gctgcgtcgg cgcggcatga gcgtggagcc ccggttcgac gcgaccatcc
    22501 acgcgccgaa ccggctgcgc atctgcgcgc tgctcgacgc cgtgcagtcg gccgagttcg
    22561 ccaccgtgca ggagaagctc gacgtctccg catcggtgct gagcaagcac gtcgcggtgc
    22621 tggtcgacgc cgggtacgtg cagcagcgcc gggccacccg caacacccgg cagcgcgtct
    22681 ggttgtcgct caccgacgcc ggccgcagcg cgtaccaggg tcacgtcgcc gcgctgcgcg
    22741 cgatcgtcgc cggtggcacc gaaccgtccg gcgagagcgc cgcgcggcac tgaccacgcg
    22801 agacatccgg cggccgaacg ccgccggcgg cagaaggagg aaccgacagt ggtggacgcg
    22861 cggctggaga tcgacgccgt ctccaagcgc tacggcgacg tggttgcctt gcaggacatg
    22921 accttcgacg tacgggccgg cgagctgttc ggcttcgtcg gcagcaacgg cgccggcaag
    22981 accaccacga tgcgcatcgt gctcggggtg ctcgcagccg actccggcca ggtgcggtgg
    23041 gacgccgaac cgatcaccgc agacacccgg cgccggatcg gctacatgcc ggaggaacgc
    23101 gggctctacc cgaagatgaa ggtcggcgag cagctgacct acctggccga gctgcacggg
    23161 atgccgcgcg gggtggcgca gacggcggcg ctgcagtggg cggaggagct cggcatcgcc
    23221 ggccggttcg gcgacgaggt gcagaagctg agcctgggta accagcagcg ggtgcagctg
    23281 gccgcggcgc tggtgcacga cccgggcatc ctggtcctgg acgagccgtt ctccgggctc
    23341 gacccggtcg cggtcgacgt gatgagcgag gtgttgcggc gcaaggcaca gcagggcatc
    23401 ccggtggtgt tctccagcca ccagctggat ctggtcgagc ggctctgcga ccgggtcggc
    23461 atcgtccgaa gtggacagat ggtggcctgc gggccggtcg acgagctgcg cgacaccggt
    23521 accgcccggc tgtcggtgct cgccccggac gcgccggccg gctgggccga cggcctgccc
    23581 ggcgtgaccg tactcgacca gcagcacggc cggaccacgc tgtcgctcgc gaccggcgcg
    23641 gacgaccagg ccgtactggc ggcggcgctc gccaccggcc cggtgcacga gttcgcccgg
    23701 cagcggccgt ccctgaccga actgttccgc aacgtggtgt ccgcaccgac cgccgaggag
    23761 gccgcatcgt gagcaacgca cagtacgacg gaccgggcgc actgagcgcc atcggcgggg
    23821 tgcggctgat cgcgcggcgc gagctcgcca cccggttgcg ggccaagtcg ttcctgatca
    23881 gtacggcgat catcgtcgtg ttcatctgcg gctacctgat cctgatgaac ttcatccaga
    23941 acagctcgtc cagctcgacg atcgggctca cccaccagac ctcggccctc gcgacgccgg
    24001 tcaccagcgc cgccgaggcg gccggccaga aggtcgacat ccgtaccgtc agcgagcagg
    24061 cgggccgcaa gcag
//
