LOCUS       NZ_CP072647            21822 bp    DNA     circular CON 02-DEC-2024
DEFINITION  Chloracidobacterium sp. MS 40/45 chromosome 2, complete sequence.
ACCESSION   NZ_CP072647
VERSION     NZ_CP072647.1
KEYWORDS    RefSeq.
SOURCE      Chloracidobacterium sp. MS 40/45
  ORGANISM  Chloracidobacterium sp. MS 40/45
            Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia;
            Terriglobales; Acidobacteriaceae; Chloracidobacterium;
            Chloracidobacterium aggregatum.
REFERENCE   1  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Genomic and phenotypic characterization of Chloracidobacterium
            isolates provides evidence for multiple species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2021) Department of Biological Sciences, Tokyo
            Metropolitan University, 1-1, Minami-Osawa, Hachioji, Tokyo 1920397,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu 1.8 assembler v. 1.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018304805.1-RS_2024_12_02
            Annotation Date                   :: 12/02/2024 00:41:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,029
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,951
            CDSs (with protein)               :: 2,951
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 7 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 353497
            Orig. end                         :: 375319
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072647.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21822
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21822
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21822
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11822](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11822)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(496..1740)
                     /locus_tag="J8C02_RS12500"
                     /old_locus_tag="J8C02_12500"
     CDS             complement(496..1740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101481.1"
                     /locus_tag="J8C02_RS12500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12500"
                     /product="acetate/propionate family kinase"
                     /protein_id="WP_211427605.1"
                     /transl_table=11
                     /translation="MNILVLNCGSSSVKFQIIATDVDAIEHNADRRLASGIIERIGGEA
                     VLTFRVDGKVSRQTAPVRDHRQAVEQILRWACSGESGIAEVQSVSDIHAIGHRVVHGGE
                     CFTHSTLITDEVIRGIEACIDLAPLHNPANLKGIRAGAEVFGPGFPQVAVFDTAFHQTL
                     NEVAYLYALPYQLYRRHRLRRYGFHGTSFRYVAYRYRQLTGKSREETNIVALHLGNGCS
                     ACAIRAGASVDTSMGYTPLEGLMMGTRAGDIDPSIVDFLEMKEGFTAREIEALLNKQSG
                     LLGVSGLTNDMRDLLDEIHEHDDRRAKLAVAMFCYRAKKYIGAYLAAMGGADAVVFTGG
                     IGENAPEIRARIGEGLEWFGLALDPAQNEALVNRREGVISREGSRLAAYVIPTDEELLI
                     ARDTARCVAGVPNPY"
     gene            2069..3898
                     /locus_tag="J8C02_RS12505"
                     /old_locus_tag="J8C02_12505"
     CDS             2069..3898
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024206.5"
                     /locus_tag="J8C02_RS12505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12505"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_211427606.1"
                     /transl_table=11
                     /translation="MRALILLCVTLWTGAPAVALPALPGAQGAAAPDALAAYNQATQAL
                     SAGKYEEAIQLYTQAIERKADFPEAYNWRGFAYRVTGRREEARQDFDRAIQLRPNYAKA
                     YELRGLTLYELGQYADAVKDYTEAFKLDPKSQSNIGYRGLCHFGLEQYDEAIRDFDAAI
                     KASPREALWFVYRGRAYEAKRDSRRALSDYEQALLLEPNNIRARTARGVALYVQGQYER
                     AIADFDVALRAEPNNQDMLAYRGQAHIELKRFDRAVKDFDELVRLDPNNARGYVGRGFA
                     RYQVKDYALAKADFDRALELDPNTGKVFCYRAMTHREMGQPEAADADFRQCFTLDVGQK
                     TVYGKAAEDVAAQLEAATPPPQTAPPRRQPPDDRAEPPDDSAGRRGRPRRVVTGTPSGQ
                     DTEPLPDDQPARPGRSTPRQDPVPTDPDPLPGGGMTTGGSPSGAVSSIGNTQALAFLRA
                     IRDGNEVRVRQMLQQGMSPNVVAANGMTALMIAADSGYGRIVQALLQAQADVSAVDSQG
                     RTALMYAARTGNIECVTALLSRGGIGVDTQDEEGMTALMHAADRGHRAAVRAILARRPN
                     VNVRSRAGMTAYTLAVRNGDIEIVNAIRAAGGR"
     gene            complement(3909..4790)
                     /locus_tag="J8C02_RS12510"
                     /old_locus_tag="J8C02_12510"
     CDS             complement(3909..4790)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS12510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_12510"
                     /product="hypothetical protein"
                     /protein_id="WP_211427607.1"
                     /transl_table=11
                     /translation="MPLNHSDHFPRRTWLCVALALLLASFGAWPSRIQARTPEAAASAD
                     CFSLDGLPPEQRARAEALFLAMLDSEALYTIAADLKPMSSGYVRFQFEVAKPDLAEIET
                     TRALLARFRCGDRFYADVLTFAAVYDGKRHAEGVVFNRAALERAIRAHPTCFAPSGLTP
                     NAHPMAVVHTVEQAEQATRWRGYGYLFGYPDAAVDFFVTAGTSQAETGKFVERDFRHIP
                     TQTRDTGGFTWAVPRGSAETDEEKHLRTRALAVLEDYRARRARLIGEGKPGVVALLREL
                     TAQPARKAAAAP"
     gene            complement(4818..5510)
                     /locus_tag="J8C02_RS12515"
                     /old_locus_tag="J8C02_12515"
     CDS             complement(4818..5510)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026253.5"
                     /locus_tag="J8C02_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12515"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_211427608.1"
                     /transl_table=11
                     /translation="MPRSLHHVLTSVILIGLPAMAATAQEKPRSPRAAAAKAAPEQKPP
                     PPAEAMLYWIREDGKFGYIDNTGKVVIPVQYENTFGFREGLAGVRINGRHGYIDRTGKL
                     VIPAVFDMTYAFREGLAWVKQDGKYGYIDKTGKMVIPPQFDDAEDFSEGLAAVKVGNLY
                     GYIDRTGKMVIPPQFSHTHRFMGGVAQVVVDRRTAYIDRTGRVLWVQKDSPKDSPREGH
                     EGGKPHRH"
     gene            5750..>6697
                     /locus_tag="J8C02_RS15205"
                     /pseudo=""
     CDS             5750..>6697
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00423.1"
                     /locus_tag="J8C02_RS15205"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="CofH family radical SAM protein"
                     /pseudo=""
                     /sec_met_domain="PF04055 (E-value: 3.7e-15, bitscore: 52.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTTDPAARQDIFAAAQACKQALVGPRATYVVNLNLNFTNVCALH
                     CTFCAFRREADARDAYAHSIDAAVQKVVWYHREYAMTEVTIQGGLNPALPVSYYFDLLR
                     ALKDACPEVHLHAYSPQEIDFIQQRSGWSLGRVFDALRDAGQGTLCGTAAEILVEPTRH
                     RICPEKITGARWLEIVRAAHRAGTRTTSTMLFGHIESLDDRVAHLDALRRLQRATGGLT
                     EFIPLPFIAAKSPLGRAVGRREIDDAEVLLVLAVARLFFGRDLVHLQLGWVKRGLALAQ
                     RSLLCGADDLGGTLLEEEISNRAGSRFGAYVPAER"
     gene            complement(6751..8202)
                     /locus_tag="J8C02_RS12520"
                     /old_locus_tag="J8C02_12520"
     CDS             complement(6751..8202)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101474.1"
                     /locus_tag="J8C02_RS12520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12520"
                     /product="circularly permuted type 2 ATP-grasp protein"
                     /protein_id="WP_211427609.1"
                     /transl_table=11
                     /translation="MFEDYDVGDFHDEMFLMPGVPRPEAAFLTQTLSMLRDEEILRRQA
                     TAEQSLLHLGITFNVYGSQDGVEKIFPFDLIPRVIAAQEWAWIEAGLQQRIRALNAFIA
                     DVYGEQRILRDGVIPRDLVLTNPAYLEACRGLRPPYDIWCHITGTDLVRDRDGQIYVLE
                     DNLRCPSGVSYVLGNRSVMKYTLPQLFEATTIRPVSTYPSKLLETLKRLAPEHTLDPTV
                     VVLTPGVANSAYFEHSFLAQQMGVELVEGRDLVVDGGLIKMRTTRGLKPVDVIYRRIDD
                     TFLDPETFRPDSLLGVPGLMQVYRAGRVALANAPGTGIADDKALYAYVPDIIRYYLSEA
                     PILPNVPTYLCRDPEARAYVLDHLEQLVVKTTGGSGGYGMLVGPTSTALERDAFRERIL
                     ARPEEYIAQPALRLSRVPTIVGDRIEGRHVDLRPYILYGEDIFVLPGGLTRVALRRGSL
                     VVNSSQGGGSKDTWVLADDHDLTRP"
     gene            complement(8391..9131)
                     /locus_tag="J8C02_RS12525"
                     /old_locus_tag="J8C02_12525"
     CDS             complement(8391..9131)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_12525"
                     /product="hypothetical protein"
                     /protein_id="WP_211427610.1"
                     /transl_table=11
                     /translation="MSVSTLQASPRPFRVSVMWLVGFGLVWLCSPALAQQESRPRRVRP
                     PVASGQPDTPPRPTSPTAFPAEPTPEQRAGNLPLAQELLALTKLPTICEHKMISLVLKE
                     MRAKPEMRGYTDIIRDFLQQHISASFMSEEMARYLAENFSERELLQLKAIVNTSAGQKM
                     FSAFENLPEATRLNDADYLQLFNEEETRQYKVFYRLPAFLKFSDCIPTLIDLGGEVTKK
                     RLDAHFPELMDDLMRRMQERPPLN"
     gene            complement(9245..9997)
                     /locus_tag="J8C02_RS12530"
                     /old_locus_tag="J8C02_12530"
     CDS             complement(9245..9997)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS12530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_12530"
                     /product="hypothetical protein"
                     /protein_id="WP_211427611.1"
                     /transl_table=11
                     /translation="MPPPLPLEVSGRRFRPAVMWLIGFGLLWLHLPVAAQQENRQPSRA
                     RSVTASGQPTGSPAPVSSLPADSQATPNRTRSEINLAAAHELLDLTGFPSLVKQTSIKV
                     LRKEIRKRPEMREAGTILRELLEDRISTQIISEEMAKYLADRFDEQELRQLKAILDTST
                     GRKMFTSFETLPTDDRVREASYLDLFDEQEKKEFQTFYRLTVFRRFSDYTLALLRIGIQ
                     SFEEQFKLQGKEFVRELVLRPREQQPRP"
     gene            complement(10001..10882)
                     /gene="hpnD"
                     /locus_tag="J8C02_RS12535"
                     /old_locus_tag="J8C02_12535"
     CDS             complement(10001..10882)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03465.1"
                     /locus_tag="J8C02_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12535"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_211427612.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-65, bitscore:
                     215.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.7e-69,
                     bitscore: 228.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDTLQPPVTAVAEGITHRSRTNFLYSFLILPRAQRRAIETVYAF
                     CRIVDDIVDGDGPATTNPQAELDRWRSEIHACFNGQTPCHPVARELKAILQTFPIPEEH
                     FLALIRGMEMDLVRRRYATFAELDEYCYHVASVIGLMCIEIFGYRHASARDYAIHLGKA
                     LQLINIVRDVPEDAARGRVYLPLDEMARFGVTEEALQDGIYDEPFIQLAAQQAARARRF
                     RFQALAALRREDRPAMVAAEIMATIYFKLLDQMEAMRFNVFHHRPRLSKLQKAMIAATL
                     LFKSHLLRFGKE"
     gene            complement(10896..11822)
                     /gene="hpnC"
                     /locus_tag="J8C02_RS12540"
                     /old_locus_tag="J8C02_12540"
     CDS             complement(10896..11822)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003810490.1"
                     /locus_tag="J8C02_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12540"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_211427613.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.2e-53, bitscore:
                     175.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-55,
                     bitscore: 184.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSVSPQSSSGAPSLEAAYAYCRRVALGHYENFPVGSLVLPKAVR
                     PHVYAIYAFARAADDFADEGTTPAAQRLANLADWRCQLEACTVGRPTHPVFLALGHTIQ
                     THDLPRQLFHDLLDAFELDVRRSRHATFEDLLDYSRCSANPVGRLMLLLFGHRDPVWHQ
                     MSDAICTALQLTNFWQDVAVDLRHDRVYLPLDDMTQHGYSETDLQACRHTPAFVNLMAN
                     LAARTEALFERGRPLCGLVPGRFGFELRLIWLGGMHILQALRRIEFNVFERRPTLDLRA
                     KASMALGAFRRTTFSATTPPTTLQIPT"
     gene            complement(12003..14756)
                     /locus_tag="J8C02_RS12545"
                     /old_locus_tag="J8C02_12545"
     CDS             complement(12003..14756)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF017077.5"
                     /locus_tag="J8C02_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12545"
                     /product="response regulator"
                     /protein_id="WP_211427614.1"
                     /transl_table=11
                     /translation="MSPTLQKAFRFTSRRLMAGFALVVLIIGGLAVACSNLVRQLRMAE
                     AEVGRSLEVLRLTADVREAALLVRLHVRGYVITGKESNVEEVRQQVFQFQQILIRLRAR
                     VGNHPVQREYLQQLEQTFLEGKDYLDWVIALRRTNREAAFEAVPGPRGNALAERMDQPL
                     EAIVQIEQKQLGDALALARHSAEALEWLIIASVGIIAALLVVAYFIVARELDKRRALLS
                     QLEYARDAALTLARRQSDFLANMSHEIRTPMNGIMGTSELLLRTPLAPNQKDLAETIRY
                     SAESLLVIINDILDFSKIEAGKLAFESSNFDLRATVEQAVETVAATARKKSLELVTLVY
                     RDVPEQLCGDAGRLRQVLLNLVGNAVKFTDRGEVVVRVTKQSETATHVTLKFSVTDTGI
                     GIPREFQENIFEAFAQVDASRARRFGGTGLGLAISKRLVQMMDGEMGVESEVGKGSTFW
                     FTATLEKADAAQPISTYELWFGLRALVADDNTTNRTVLAQLLTDFGMFCEVVASPEEAI
                     AALREAVAQGDPFRVALLDAHLPTVDGLSLIQRIREEKTFDTLACILLTPPPLPDLDEI
                     QRMGAAACLAKPVRMMALKEALRAALGKPRPRTPKTNSQETPRPTIPTPTGVPRPDVAQ
                     PRGAPPQGGQPKTVLLVEDNVINQQVARRMLELLGYQVGVAHSGLEAIERFQTQPPDAI
                     LMDCQLPEMDGYTATQHIREQERTLGRHVPIIALTANALAGERERCLAAGMDDYLAKPF
                     RMKDLEEVMQRVLGAASQPTPAAQPEHRTGEIPAGNGESEPPLLDADAFWIGTGITPGS
                     HGAHQLAHQIIATFRSDVAAQMQELRAAMERQDAKEVRAIAHRLYGSAAQLGARQLARA
                     LKRLEKAPDASTWPAQFQVVEEVSAATSRAFDEALQRKALVQPPHG"
     gene            complement(14842..15792)
                     /locus_tag="J8C02_RS12550"
                     /old_locus_tag="J8C02_12550"
     CDS             complement(14842..15792)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015279430.1"
                     /locus_tag="J8C02_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12550"
                     /product="BsuBI/PstI family type II restriction
                     endonuclease"
                     /protein_id="WP_211427615.1"
                     /transl_table=11
                     /translation="MADRAETQAADRVSEALDILRALDVPQKQQNKRSALTLLALLGLT
                     PQKDWIQAANPCLGINEMMKHFGKKYAPNTRETVRRFTVHQFVQTGLVLANPDNPARPV
                     NSPDTCYQVTPALLEIVRAYGTASWNESLRNFVNSAEALRRLQPGERAIPLIPVRLPDG
                     RQLDLTAGGQNRLVKKIVEEFCPRFTPGGVLVYVGDTGRKQRHLETDYLTKLGVVFDEH
                     GKMPDVIVHLPEKHWLVLIEAVTSHGPINVKRQNELRGLFKGATAGLVFVTAFLTRRAM
                     ARYLSEIAWETEVWVAEAPSHIIHFNGERFLGPYE"
     gene            complement(15785..17308)
                     /locus_tag="J8C02_RS12555"
                     /old_locus_tag="J8C02_12555"
     CDS             complement(15785..17308)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020741735.1"
                     /locus_tag="J8C02_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12555"
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="WP_211427616.1"
                     /transl_table=11
                     /translation="MGLGLLETVEKTRRGLSEHMGRHHRALLGQFFTPAPIALFMAESF
                     EARQPALRVLDAGAGIGSLSAAFVTAMARRERRPHAISITAFEIDSRLIPYLQTTLDLC
                     QAASRAAGIHFDARIVEGNFLEAGPGTFTGDLFTPGAGERFDCAILNPPYRKIRSHSRD
                     RQLLRAIGVETSNLYTGFLAVATTLLAPGGEIVAITPRSFCNGPYFEPFRRFFLKEMRF
                     RRIHVFDRRDRAFADDEVLQENIIFRAVKAADGTDDVVVSGSPDPKDANRHIQTVKHAD
                     LVRPGDPHLFIHVVPDTDGQCVRRRMLELECTLEELGLAVSTGRVVDFRASHLLCLQPG
                     PNTVPLIYPCHLQRGFVGWPDRQARKPNALALGLGAQKLLVPKGCYVLVKRFSAKEERR
                     RVVAGIYDPLRLPPAEQVAFENHLNFYHVRGAGLPVNLAKGLATFLNSTLVDAYFRQFS
                     GHTQVNATDLRSLRYPARDKLVRIGQRIGQTFPDQAEVDRLVAEMVSHG"
     misc_feature    complement(17436..17451)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            17525..18472
                     /locus_tag="J8C02_RS12560"
                     /old_locus_tag="J8C02_12560"
     CDS             17525..18472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101465.1"
                     /locus_tag="J8C02_RS12560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12560"
                     /product="alpha-E domain-containing protein"
                     /protein_id="WP_211427617.1"
                     /transl_table=11
                     /translation="MLSRVADSIFWMSRYIERAENIARFVDATMTLTLDLPADDTAAWV
                     ELVASVGDPVDFAARYGTPTPAAVLRYLTFDEQNPNSILTTLARARENARCVRDTISSE
                     MWEQANRFYLDVKSAATQGRFGAMPHAFFTQVKMSSHLFVGVTDSTMSHGEAWHFNRIG
                     RLLERADKTACILGVERFNATTLAGSSLIDDLHWSGLLKSASAHEMYRKRFGRIEPRRV
                     FEFLLLSREFPRAAHYCLLRCVESVHAISGTLPGTYTNLPEQRLGRLAAQLDYAGVEDI
                     LPPESPHDARPFLNRFRRDLYAAGDAIAMTFFPN"
     gene            18485..19213
                     /locus_tag="J8C02_RS12565"
                     /old_locus_tag="J8C02_12565"
     CDS             18485..19213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101464.1"
                     /locus_tag="J8C02_RS12565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12565"
                     /product="peptidase"
                     /protein_id="WP_211427618.1"
                     /transl_table=11
                     /translation="MTFCLGIKTVEGLIAVADTRITSGTECRTSRKLTVHRAAAAPVFV
                     MTSGLRSARDKVVTYFDEWLRGETVLHRRLYELVNAYGEQVRRVVREDHAMLERDGLRF
                     DLFSIIGGRLPDDGEHRLFLVYPQANWVEIGESSPYAIIGNAFYGKPILDRMLDYGCSL
                     EVALKAALLAFDCTLTSASDVSYPLDVAVLRAGASDFLEHRFTEPDMASYAVWWRTNLR
                     RLVTDAPGSWLTFLNLESGL"
     gene            19210..19554
                     /locus_tag="J8C02_RS12570"
                     /old_locus_tag="J8C02_12570"
     CDS             19210..19554
                     /GO_function="GO:0009927 - histidine phosphotransfer kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013767.5"
                     /locus_tag="J8C02_RS12570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12570"
                     /product="Hpt domain-containing protein"
                     /protein_id="WP_211427619.1"
                     /transl_table=11
                     /translation="MSSLDLDTIATLKSLDDGDGFFADMVNTFLDNAKGTFEQLHAAHV
                     ADDIRALERAAHKLRGAASTIGAQNLMAMCEALETSARTGHVPDVAGSVAAIETELQHV
                     RLALQAEMQN"
     gene            19583..20404
                     /locus_tag="J8C02_RS12575"
                     /old_locus_tag="J8C02_12575"
     CDS             19583..20404
                     /NRPS_PKS="Domain: PKS_KR (14-184). E-value: 1.4e-15.
                     Score: 49.7. Matches aSDomain:
                     nrpspksdomains_J8C02_RS12575_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101462.1"
                     /locus_tag="J8C02_RS12575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12575"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_211427620.1"
                     /sec_met_domain="adh_short (E-value: 2.8e-37, bitscore:
                     124.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-34, bitscore:
                     115.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPIVDIGEVLQGQVAIVTGASSGIGAAVARELARAGAAVAVNYA
                     GNPAGAQSVADAITGAGGRAIIVRADVSIEAEVTAMFSAVLDAFGRLDILVGNAGLQRD
                     APFVEMTLEAWERVIAVNLTGQFLCTRAAVRQFLAQEARPEVSSALGKIICISSVHDVI
                     PWAGHINYAASKGGLSLLVKSLAQEVAEKKIRVNAVSPGAIRTPINRAAWETPEAEAAL
                     LKLIPYERVGEPEDIGRAVVWLASDASDYITGATLYVDGGMTLYPEFREGG"
     aSDomain        19625..20134
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8C02_RS12575_PKS_KR.1"
                     /evalue="1.40E-15"
                     /label="J8C02_RS12575_PKS_KR.1"
                     /locus_tag="J8C02_RS12575"
                     /protein_end="184"
                     /protein_start="14"
                     /score="49.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGASSGIGAAVARELARAGAAVAVNYAGNPAGAQSVADAIT
                     GAGGRAIIVRADVSIEAEVTAMFSAVLDAFGRLDILVGNAGLQRDAPFVEMTLEAWERV
                     IAVNLTGQFLCTRAAVRQFLAQEARPEVSSALGKIICISSVHDVIPWAGHINYAASKGG
                     LSLLVKS"
     CDS_motif       19631..19774
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8C02_RS12575_0001"
                     /evalue="5.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="J8C02_RS12575"
                     /protein_end="64"
                     /protein_start="16"
                     /score="19.1"
                     /tool="antismash"
                     /translation="IVTGASSGIGAAVARELARAGAAVAVNYAGNPAGAQSVADAITGA
                     GGR"
     gene            20404..21066
                     /gene="bluB"
                     /locus_tag="J8C02_RS12580"
                     /old_locus_tag="J8C02_12580"
     CDS             20404..21066
                     /EC_number="1.13.11.79"
                     /GO_function="GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032363 - FMN catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bluB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101461.1"
                     /locus_tag="J8C02_RS12580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_12580"
                     /product="5,6-dimethylbenzimidazole synthase"
                     /protein_id="WP_211427621.1"
                     /sec_met_domain="PF00881 (E-value: 5.4e-27, bitscore: 90.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDWMFSEAERAAVYRAIHTRRDIRSTFLPQPIPDAVLWRLLGAA
                     AAAPSVGFMQPTEIIVIRDAEVRRQIHAHFEGVNRAAAEVYADADRRAYDALKLAAIVE
                     TPLNLCFTCDTTTRRGRGLGRQTMPETAVFSTVCAVQNVWLAARAENIGVGWVSILEPE
                     TVKTRLDIPAHLTLVAYLCVGYVSDFPSQPELETKGWEHARDLTEMVHFDRYGVRRP"
ORIGIN
        1 ttgggtcggc ggcggcgctt ccggtttctt ctcttcggaa gtacaaccgc tcgataaccc
       61 caacccggcg gcaacaacca gcccgagtgt ggcggttgcc agtcctgaat ggcgacgagt
      121 aagcatgggt cctgctggct cctggggcag tgatgaagta gagcaggcgc acgctagcac
      181 gggctccggg ttttgcctag cgccaggggc gacgggcttg aacagtctca ataaaggttc
      241 ttctttcctg cgtttttggg tgtgattttg agcatgagat cctcccgacc gcctcacgca
      301 gagccgccgg gaggcaattt tccattctcc gcggcctggc gtgagggaga tggcgagagg
      361 gatgttccgg ggtggatttg tatccccaac ctttactttg ctcgcgcaga gccgcggaga
      421 ggtgattctt cattctctgc ggctccgcgt gaggaaggat gtccggcgga acggattgcg
      481 tgtcatgact gtggttcagt agggattcgg aacgccggcc acacagcgcg ccgtgtcgcg
      541 ggcaatgagc agctcttcat cggtcgggat gacataggcc gccagacggc tgccttcgcg
      601 gctgatgaca ccttccctgc ggttgacaag cgcctcgttt tgcgccgggt caagtgcgag
      661 accgaaccac tccagcccct caccgatacg cgcgcggatt tcaggggcgt tttctccaat
      721 cccgcccgtg aaaacaacgg catccgcgcc acccatcgcg gccagatagg ccccgatgta
      781 ctttttggcc cggtagcaga acatggccac ggccagtttg gcgcggcggt cgtcatgctc
      841 gtggatttca tcgagcaggt cgcgcatatc gttggtcagc ccggaaacac ccagcaaccc
      901 cgactgtttg ttgagcaatg cctcgatttc ccgcgccgtg aagccttctt tcatttcaag
      961 gaaatccaca atcgaggggt caatgtcgcc ggcgcgggtg cccatcatca gaccttcgag
     1021 cggggtgtag cccatggacg tgtccaccga ggctcccgcc ctgatggcgc aggcagaaca
     1081 gccattgccc agatgaagtg cgacgatgtt ggtttcctcg cgcgatttgc ccgtcagttg
     1141 acggtaacgg taggccacgt agcgaaagga ggttccgtga aaaccgtacc gccgcagcct
     1201 gtgccgccga tagagctggt agggcagggc gtagagatac gccacttcgt tcagggtttg
     1261 atgaaaggct gtgtcaaaga cagccacctg gggaaagccg ggcccgaaca cctccgcccc
     1321 ggcccgaatg cccttcagat tggccgggtt atggagtggc gccagatcaa tacaggcttc
     1381 gatgccacgg atgacctcat ccgtgatgag cgtcgagtgg gtaaagcact cgccgccgtg
     1441 aaccacccgg tgtccgatgg cgtgaatgtc cgagacgctc tggacttccg caatccctga
     1501 ttcgccggaa caggcccagc gcaggatttg ttcgacggcc tggcgatggt cccggacggg
     1561 ggcggtttgg cgtgaaacct tgccgtccac gcggaaggtc agcacggcct caccgccgat
     1621 gcgttcgatg atgccggaag ccaaccggcg gtcggcattg tgctcgatgg cgtccacgtc
     1681 ggtggcaatg atttgaaact tgaccgacga actgccgcag ttgagaacga gaatgttcat
     1741 agttccaagc ccttcggaag gagtctgtca gaggaagatg tcagaacgtg cagtatgacc
     1801 ggcgccgcct ggcagactgg acggttgcct tccaaagtcg ccgctctcca accgggggcg
     1861 ggaacataac ggtcgctttg gtgcatggcc cgtggtgggt ggctttctgc gcggtgtcgt
     1921 tggggggcgc ccatggcaac ccctcgttgc cattctgttt ttcaagtagg atggaaggca
     1981 acgtctgccc gcgcaggcac gtccacgtgc ctgtgtatca acgaatgaca gtctcgaaag
     2041 cggcgacaag agacgaggaa accatcccat gcgtgccctg atcctgcttt gcgtgaccct
     2101 gtggactggc gctccggctg ttgccctccc ggccctcccc ggcgctcagg gggcggccgc
     2161 gcccgatgcc cttgcggcct acaaccaggc cacccaggcg ctgtccgccg ggaagtacga
     2221 agaagccatc cagttgtaca cccaggccat cgagcgcaag gcagacttcc cggaagcgta
     2281 caactggcgc ggatttgcct accgggtcac cgggcggcgc gaggaagccc gccaggactt
     2341 cgaccgtgcc atccagttgc gccccaacta cgccaaagcc tatgaactgc gcggcctgac
     2401 gctctacgaa ctcggccagt acgccgatgc cgtcaaggac tacaccgaag cgttcaagct
     2461 cgatcccaag tcccagtcca atatcggcta ccgcggcctg tgccatttcg ggctggagca
     2521 gtacgacgaa gccatccgtg actttgatgc cgccatcaag gccagccccc gtgaagcgct
     2581 ctggtttgtc tatcggggcc gggcttacga ggccaaacgc gacagccggc gcgccctgtc
     2641 ggattatgag caggcattgc tgctggagcc gaacaacatc cgggcgcgga cggcgcgggg
     2701 cgtggcactc tacgtgcagg ggcagtacga acgcgccatc gccgatttcg acgtggccct
     2761 gcgcgccgaa ccgaacaatc aggacatgct ggcctaccgc ggccaggccc acattgaact
     2821 caaacgcttc gaccgggcgg taaaggactt cgacgagctc gtgcgcctcg atcccaacaa
     2881 cgcacgcggc tacgtcggac gcggttttgc gcgctaccag gtcaaggact atgcgctggc
     2941 gaaagccgat ttcgaccgcg cgctggaact cgaccccaac accggcaagg tcttctgcta
     3001 ccgcgccatg acgcaccgcg agatggggca accggaggcc gccgatgccg atttcaggca
     3061 gtgcttcacg ctcgatgtcg ggcagaaaac cgtgtacggc aaggccgccg aagatgtggc
     3121 cgcacagctt gaggcggcca caccaccgcc ccagaccgct ccaccacgcc gccagccgcc
     3181 ggatgaccgc gccgaaccgc cggacgactc cgccgggcga cgcgggcgtc cacggcgggt
     3241 cgtgaccggg acgccttccg gtcaggatac cgaacccctg ccggatgacc agccggcgcg
     3301 cccggggcgt tccacgccgc gccaggaccc tgtcccaacc gatcctgacc cgctgccggg
     3361 aggcgggatg accacaggtg gctcaccttc cggcgcggta tcaagcatcg ggaacaccca
     3421 ggcattggct tttctgcggg cgattcggga cggcaacgaa gtgcgcgtcc gccagatgct
     3481 tcagcagggg atgtcgccca acgtggtggc ggccaacggc atgacggcgt tgatgatcgc
     3541 ggcggatagt ggttacgggc gcattgtcca ggcgttgttg caggcgcagg ccgatgtcag
     3601 cgcggtggat agtcagggac gaacggcact catgtatgcc gcgcgcaccg gcaacatcga
     3661 gtgtgtgacg gcgctgctca gtcggggtgg catcggggtt gatacccagg atgaagaagg
     3721 catgacggcg ctgatgcacg ccgctgaccg gggccaccgg gcggccgtac gggcgattct
     3781 ggcccggcgt cccaacgtca atgtgcgcag tcgcgccggg atgacggcct acacgctggc
     3841 cgtgcgcaac ggcgacatcg aaatcgtcaa cgccatccgc gctgccggcg gccgctgact
     3901 gctgccggct acggggcggc ggcggctttc cgcgccggct gggccgtcaa ctcccgcagc
     3961 agggccacga caccgggttt accttcgccg atgagtcggg cgcggcgcgc gcggtagtct
     4021 tccagtaccg ccagcgccct ggtgcgcagg tgtttctcct cgtcggtttc cgcgcttcct
     4081 ctgggaaccg cccaggtaaa tccgccggtg tcccgcgtct gggtcgggat gtgccggaaa
     4141 tcccgttcga caaacttgcc ggtttccgcc tgagaggttc cggccgtgac gaagaaatcc
     4201 acggcggcgt cgggatagcc gaaaagatag ccgtaacccc gccagcgggt ggcctgttcc
     4261 gcctgctcga ccgtgtgcac gacggccatc gggtgcgcgt tgggcgtcaa tccagaaggc
     4321 gcaaaacagg ttggatgcgc ccggatggcc cgctccaaag cagcacggtt gaacaccacg
     4381 ccttcggcat ggcgtttccc gtcatacacg gctgcaaagg tgagcacgtc ggcataaaag
     4441 cggtcgccac accggaaacg ggccagcagg gcgcgcgtcg tttcgatttc agccaggtcg
     4501 ggtttggcga cctcgaactg gaaacgtacg tagccgctgc tcatcggctt gagatcggcg
     4561 gcaatggtgt acagggcttc ggaatccagc atggccagaa acaaggcctc ggcgcgcgcc
     4621 cgttgttccg gcggcagacc gtccagcgaa aaacagtcgg ccgacgcggc ggcttccggg
     4681 gtgcgggcct ggattcggct tggccacgcg ccgaacgacg ccagcagcag tgccagcgct
     4741 acgcatagcc aggtgcggcg cggaaagtgg tcggaatggt tcaggggcat ggagcggaac
     4801 cagcgggcga ggccgggtca gtgcctgtgc ggctttccgc cttcgtggcc ttctctgggg
     4861 ctgtctttgg gactgtcttt ctgaacccag agcacgcgcc cggtgcggtc aatgtaggcc
     4921 gtccgcctgt ccaccacgac ctgcgccacc ccgcccatga agcggtgcgt gtgggaaaac
     4981 tggggcggaa tgaccatctt gccggtgcgg tcaatgtagc cgtagagatt gccgactttg
     5041 accgcggcca gtccttcgga aaagtcttcg gcgtcgtcaa actgcggtgg aatgaccatc
     5101 ttgccggttt tgtcaatgta accgtatttg ccgtcctgtt tgacccacgc cagcccttcc
     5161 cggaaagcat aggtcatatc aaagacagcc ggaatgacga gcttgcccgt gcggtcaatg
     5221 tagccgtgcc tgccgttgat gcgtactccg gccagccctt cccggaagcc aaaggtgttt
     5281 tcgtactgga cgggaatgac gactttgccg gtgttgtcaa tgtagccgaa tttgccgtct
     5341 tcccgaatcc agtagagcat ggcttccgcg ggcggcggcg gcttttgttc cggcgcggct
     5401 tttgcggcag ccgctctggg ggaacgtggt ttttcctgcg ccgtggcggc cattgccggc
     5461 agcccgatca ggatgactga tgtcagtaca tgatgcagag aacgaggcat gggacaaaga
     5521 cctcacccaa aaacgtgtgt gttggctggc tggcgtccgc cggctgccac tatagagcgg
     5581 atgtttttgg atgggaagtc gcggaaacag gaaaaatatg gaatccagcc gtgcttgtga
     5641 cccccggtgc aacgtggcag actccacgat ggctatggcg aatgtgacgg ctgttctgga
     5701 aaaagctctc cgctttgagc cactgacgcc ggcggaagcc cggctgctca tggggacgac
     5761 ggacccggcg gcgcggcagg acatttttgc ggccgcgcag gcatgcaagc aggcgctggt
     5821 cgggccgcgt gcgacttacg tcgtcaatct gaatctcaac ttcaccaacg tctgcgccct
     5881 gcactgcacc ttctgcgcct ttcgccgtga agctgacgcc cgcgacgcct atgcccacag
     5941 cattgacgcc gccgtgcaga aggtcgtgtg gtatcaccgt gagtacgcca tgaccgaagt
     6001 gacgattcag ggtggcctca acccggctct tccggtgagc tactactttg acctgctgcg
     6061 cgcgctcaag gacgcctgcc cggaggtgca cctgcatgcc tattcgccgc aggaaattga
     6121 cttcatccag cagcggagcg gctggtcatt gggccgggtt tttgatgccc tgcgcgacgc
     6181 cgggcagggc acgctctgcg ggacggctgc cgaaatcctc gttgaaccga cacgccatag
     6241 aatctgcccg gagaaaatca ccggggcgcg ctggctggaa atcgtacggg ctgcgcaccg
     6301 ggccggcaca cgcacgacat ccaccatgct gtttgggcac atcgagtcgc tggatgaccg
     6361 ggtggcgcac ctggacgcct tgcgccggtt gcagcgggcg accggcggtt tgacggagtt
     6421 catcccgctg ccgttcattg ccgccaaatc gccgctgggg cgggccgtgg gccgccgtga
     6481 aattgacgac gcggaggtgc tgctcgtcct ggcggtggcc cggctgttct tcggacgcga
     6541 tctcgttcac ctgcaactcg gatgggtcaa acgggggctg gcgctggccc agcgcagcct
     6601 gctctgtggc gcggatgacc tggggggcac gttgcttgaa gaggaaattt ccaaccgtgc
     6661 cggatcgcgt tttggcgcgt atgtcccggc cgaacgcctg gccgtgacca ttgccgcgct
     6721 ggggctggag ccggttcagc ggacaaccac ctacggccgg gtcaggtcgt ggtcatccgc
     6781 cagcacccat gtgtccttgc tgccgccgcc ctgtgaggag ttgaccacca gcgagccacg
     6841 gcgcagcgcc acgcgcgtca gtccgccggg cagcacgaag atgtcttcgc catagagaat
     6901 gtacgggcgc aggtccacat ggcgcccctc gatgcggtcg ccgacaatcg ttgggacgcg
     6961 cgacaggcgc agcgccggct gggcaatgta ctcttccggc cgcgccagga tgcgttcccg
     7021 gaaggcatcg cgttccagcg ccgtcgaggt tggtccgacg agcatgccgt acccgcctga
     7081 gccgccggtc gttttgacca caagctgctc cagatgatcg agaacataag cccgtgcttc
     7141 cgggtcacgg cacaggtagg tcggcacgtt tggaaggatc ggtgcttcgg agaggtaata
     7201 gcggatgatg tcggggacgt aggcgtagag ggccttgtcg tcggcaatgc ccgtgccggg
     7261 ggcattcgcc agggcaacac ggccggcccg atagacctgc atcaaaccgg ggacgcccag
     7321 cagggaatcg ggacggaagg tttcgggatc gagaaacgtg tcgtcaatcc ggcggtaaat
     7381 gacatccacc ggtttgaggc cgcgggtcgt ccgcatcttg atgagtccgc catccaccac
     7441 gaggtcgcgc ccttccacca gttcgacgcc catttgctgc gccaggaagg aatgctcgaa
     7501 gtaggctgag ttcgccacgc ccggcgtcag cacgacaacc gttgggtcaa gggtatgctc
     7561 cggcgccagc cgcttgagcg tttcaagcag cttgctggga taggttgaaa ccgggcgaat
     7621 cgtggtcgct tcaaagagct gcggcagggt gtacttcatc accgagcggt tgccgagcac
     7681 atacgacacg cccgacggac agcgcaggtt gtcttccagg acgtagattt gcccgtcgcg
     7741 gtcgcggacc agatcggtgc ccgtgatgtg acaccagatg tcgtacggcg ggcgtaagcc
     7801 ccggcaggct tcgaggtagg ccggattggt gagcacgaga tcgcgtggga tgacgccgtc
     7861 gcgcagaatc cgctgttcac catacacgtc ggcgatgaag gcattgagtg cccgaatccg
     7921 ttgctgaaga ccggcttcaa tccaggccca ttcctgggcg gcaatgacgc ggggaatgag
     7981 gtcaaagggg aagattttct ccacgccgtc ctggctgcca tagacattga aggtaatgcc
     8041 caggtgcagc agggactgct cggccgtggc ctgccgccgg aggatttcct catcgcgtag
     8101 catggacagc gtttgcgtga ggaaagctgc ttccgggcgt ggcacgcccg gcatcagaaa
     8161 catctcgtcg tggaagtcgc caacgtcgta gtcctcgaac atgaccgtga acctgaccgt
     8221 gccgggcgcg ccgtccaggc gtggaacagg gcgtcccctg ggtcggggcc ggattctgcg
     8281 ccgacgttgg ggctggacga tcgctgtgcc aaggattgcc ggacaaccat agcgaacccg
     8341 ccggtttgtc gtccagtcgg gggatggagc cgccagggtc gtccgtccgc tcagttcagc
     8401 ggtggtcgct cctgcatacg acgcatgaga tcgtccatca gctcagggaa atgggcatcg
     8461 agacgcttct tggtcacttc accgccgagg tctatcagcg tcggaataca gtcggaaaac
     8521 ttcagaaaag ccggaaggcg gtagaaaacc ttatactgtc tggtttcctc ctcgttaaag
     8581 agctgaaggt agtcggcatc gttgagtcgc gtcgcttcgg gcaggttttc aaaagcactg
     8641 aacatctttt gtccggcgct ggtgttcacg atggccttga gctgaagcaa ctcgcgttct
     8701 gaaaaatttt cagccagata ccgcgccatc tcttcggaca taaaagatgc tgaaatatgc
     8761 tgctgcagga agtcacggat gatgtcggtg tagccgcgca tttcaggttt ggcgcgcatt
     8821 tctttgagta ccaggctgat cattttgtgt tcgcagatag tgggtaattt cgtcagggcg
     8881 agcagttcct gtgcaagcgg caggttccct gcgcgttgtt ccggggtagg ctctgccggg
     8941 aaggccgttg gggaggtcgg acggggaggt gtgtccggct gaccagaggc gaccggcggg
     9001 cgcacccggc gcggtcggct ttcctgttgt gccagggccg gggagcacag ccaaaccagt
     9061 ccaaagccaa ccaaccacat cacagacacc ctgaaaggac gaggggaagc ctgaagcgtg
     9121 gaaactgaca tggtttctcc tttccagagt gaaagccggc tggaagtaca tacctggcag
     9181 tcatcggggt gagctgccgg aaggacattc gttgccaggc tgaacgctgc caaaatggaa
     9241 atgtctatgg tcttggctgt tgttcccgag gccggagaac aagctctctg acgaattctt
     9301 ttccctgaag cttgaactgt tcttcaaagc tctgtattcc aatccgaagc aacgccaggg
     9361 tatagtcaga aaatctccta aagacagtaa gccggtagaa ggtctggaac tctttttttt
     9421 cctgttcatc gaagaggtca aggtaactgg cttcccgaac ccgatcatct gtcggcaggg
     9481 tctcaaagct ggtgaacatt ttgcgtccgg tgctggtatc caggatagcc ttgagctggc
     9541 gtagctcctg ctcgtcgaat ctgtcagcca gatacttggc catttcttct gaaatgattt
     9601 gcgtcgagat gcgatcttca agaagttccc gcaggatggt tcccgcttca cgcatttcgg
     9661 ggcgcttgcg tatttccttc cgcaggacct tgattgaggt ctgcttgaca agagaaggga
     9721 atccggtcag gtcaagcagt tcatgtgccg ccgcaaggtt gatttcgctt cgggtccggt
     9781 ttggcgttgc ctgactatca gcgggaaggc tggagactgg cgccggcgag ccggttggtt
     9841 gaccggaggc ggtcacagaa cgtgctcttg acggctggcg gttttcctgt tgcgctgcaa
     9901 ccggcaggtg cagccagagc agaccaaagc caatcagcca catcaccgcc ggccggaaac
     9961 ggcgaccgga aacttcaagt ggaaggggcg gcggcatggg ctactccttt ccaaaacgca
    10021 gcaggtgcga cttgaacaaa agcgttgccg caatcatcgc tttctgaagc ttggacagac
    10081 gtgggcggtg gtgaaaaaca ttaaaccgca ttgcttccat ctggtcgagc agtttgaagt
    10141 agattgtcgc catgatttca gccgccacca tggcggggcg gtcttcacgc cgcagcgccg
    10201 ccagggcctg aaagcgaaaa cggcgcgccc gcgccgcctg ctgtgccgcc aactggatga
    10261 acggttcgtc gtaaatccca tcctgcaaag cttcttccgt cacgccgaac cgggccattt
    10321 catcgagcgg cagatacacc cgtccccggg ccgcatcttc cggcacatcc cggacgatgt
    10381 tgataagctg gagcgccttg cccagatgga tggcatagtc gcgggcgctg gcgtgccggt
    10441 agccgaagat ttcaatgcac atcagcccga tgaccgaggc gacgtgatag cagtactcat
    10501 ccagttccgc aaatgtcgcg taacgtcggc gcaccaggtc catttccatg ccacggatga
    10561 gcgccagaaa gtgctcttcg gggatgggaa aggtctgaag gatggctttg agttcgcggg
    10621 ctaccggatg gcagggggtt tgcccgttga agcaggcatg aatttcgctg cgccagcggt
    10681 cgagttccgc ttgtgggttg gtcgttgccg ggccatcgcc gtccacgatg tcgtccacga
    10741 tgcggcaaaa ggcatagacg gtttcaatgg cgcgccgttg cgccctgggc aggatgagaa
    10801 acgaatagag aaagttggtg cgtgaacggt gtgtgatgcc ttccgcaacg gccgtgaccg
    10861 gaggctggag tgtatcgtcc attgttgaac atcaatcagg ttggtatctg aagcgtcgtc
    10921 ggtggggtgg tggccgaaaa cgttgtccgg cgaaaggcgc caagggccat ggacgctttg
    10981 gcgcgcaggt caagcgtcgg tcgccgctca aaaacgttga actcgatgcg gcgcagcgcc
    11041 tgcagaatgt gcatgccacc cagccagatg aggcgcagtt caaacccgaa acggccgggg
    11101 acgagtccgc acagggggcg gccgcgctcg aaaagcgcct cggttcgcgc cgccaggttg
    11161 gccatcaggt tcacaaaggc cggcgtgtgg cggcacgcct gcagatcggt ttcgctgtac
    11221 ccatgctgcg tcatgtcgtc caacgggagg tacacccggt cgtggcgcag gtccaccgcc
    11281 acatcctgcc agaagttggt gagctggagc gccgtgcaga tggcatccga catctggtgc
    11341 cacaccggat cgcggtggcc gaacagcagg agcatgagcc gcccgaccgg attggccgaa
    11401 caccggctgt agtccagcag gtcctcgaag gtcgcgtgcc gcgagcggcg gacatcgagt
    11461 tcaaaggcgt cgagcaggtc gtggaaaagc tgccgtggca ggtcgtgggt ctgaatggtg
    11521 tggcccaggg ccagaaacac cgggtgcgtg gggcggccta ctgtgcaggc ttcgagctgg
    11581 cagcgccagt cggccaggtt ggcgagccgc tgggcggccg gcgtcgtgcc ttcatcggca
    11641 aagtcgtcag cggcgcgggc gaaagcgtaa atggcataga cgtgcggacg cacggccttg
    11701 ggcaagacca gcgaaccgac cgggaagttt tcatagtggc cgagagcgac gcgccggcag
    11761 tacgcataag cggcttcaag tgaaggggcg ccagaggaag actggggcga tacagaggac
    11821 acgatgtgca acaacctgcc gttggaacaa agctgcgggt acggccggag ccatgcgcca
    11881 cgccgccatg ggcggtgctc cggtttaccg ccagacgata tttgttgcgc taccggccgc
    11941 cgtcaagggc gttttcgcag gtcgttttcg ggcgtcgggc gtgcccgcat tggcggccac
    12001 ggctagccat gcggcggctg aacgagagcc ttccgttgga gagcttcatc aaaggcgcga
    12061 ctggtggccg ccgacacttc ctccaccacc tgaaactgcg caggccacgt gctggcgtca
    12121 ggcgcttttt caaggcgctt gagtgcccgc gccagttgcc gggccccaag ctgggcggcg
    12181 ctgccgtaga ggcggtgggc aatggcgcga acctctttgg cgtcctgccg ttccatggcc
    12241 gcgcgcagtt cctgcatctg ggccgcgaca tcggaccgaa acgtagcgat gatctggtgt
    12301 gccagttgat gggcgccgtg gcttccgggt gtgatgccgg tgccaatcca gaacgcatcg
    12361 gcatccagca gggggggctc gctttcgcca tttccagccg ggatttctcc ggtgcggtgt
    12421 tccggctgtg cggctggtgt cggctgtgaa gccgcgccca gcacccgctg catcacctct
    12481 tcgaggtctt tcatcctgaa gggtttggcc agatagtcat ccatcccggc tgccaggcag
    12541 cgttcacgtt cgccagccag ggcattggcc gtgagtgcaa tgatcggcac gtggcgtccc
    12601 agcgtgcgtt cctgctcccg aatgtgctgc gtggcagtgt agccgtccat ttcaggcaac
    12661 tgacaatcca tcaggatggc atccggcggc tgggtctgaa accgttcaat ggcttcaagt
    12721 ccactgtgcg ccacgccgac ctgatagcca aggagttcca gcatgcggcg cgccacctgc
    12781 tggttgatga cattgtcttc aaccagcagg acggttttcg gctggccgcc ctgggggggg
    12841 gcgcccctgg gttgggcgac atcgggccgg ggcacacccg tgggcgtcgg gatggtgggg
    12901 cgtggggttt cctgcgagtt ggtctttggg gtgcgggggc gtggcttgcc gagcgctgcc
    12961 cgaagcgctt ccttgagcgc catcatccgt accggcttgg caaggcacgc tgctgctccc
    13021 atccgctgga tttcatccag gtcgggcaac ggcggcggtg tcagcaaaat gcaggccagc
    13081 gtgtcaaagg ttttttcctc acggatacgc tgtatcagcg acagcccatc cacggtcggc
    13141 aggtgggcgt ccagcagtgc cacccggaac ggatcgccct gcgccaccgc ctcgcgcagg
    13201 gcggcgatgg cttcttccgg gctggccacg acttcgcaaa acatgccaaa gtcggtcagc
    13261 agttgcgcca gcaccgtgcg gttggtggtg ttgtcgtccg caaccagggc ccgcagcccg
    13321 aaccacagct catacgtgga gataggctgc gcagcatcgg ccttttcgag cgtggcggtg
    13381 aaccagaacg tcgagccctt gcccacctca ctttcaacgc ccatctcgcc gtccatcatc
    13441 tggacgagcc gtttggaaat ggccagtccc agtcccgtcc cgccaaaacg gcgcgcccgt
    13501 gaggcatcca cctgggcaaa cgcctcgaaa atgttttcct gaaactcccg cgggatgcca
    13561 atcccggtgt cggtcacgga aaacttcagg gtgacgtggg ttgcggtttc ggactgtttc
    13621 gtcacccgca cgacgacttc gcccctgtcg gtgaacttca cggcattgcc cacgaggttg
    13681 agcaacacct gccggagccg gccggcgtcg ccgcaaagct gttcgggcac atcgcggtac
    13741 accagcgtga cgagttcaag ggatttcttg cgggccgtgg cggccaccgt ctcgacggcc
    13801 tgctccacgg tggcccgcag gtcgaagttg cttgactcaa aggcgagctt gccggcttca
    13861 atcttcgaga aatcgagaat gtcgttgatg atgaccagga gcgactcggc gctgtagcgg
    13921 atggtttcag ccaggtcttt ctggttgggg gccaggggcg tgcgcaggag gagttcgctc
    13981 gtgcccatga tgccgttcat aggcgtacgg atttcgtggc tcatgttggc caggaaatcg
    14041 gattgccgtc gcgccagggt cagggctgca tcacgggcgt attcgagttg ggaaagcagt
    14101 gcccggcgtt tgtcgagttc gcgtgccaca atgaaatagg cgacgacgag cagcgccgca
    14161 atgatgccca cactcgcaat gatgagccac tccagggctt cggcgctgtg gcgcgccagc
    14221 gccagcgcgt cccccaactg tttttgctcg atctgcacaa tggcttccag cggctggtcc
    14281 atgcgctcgg ccagggcgtt tcccctgggt ccgggcaccg cctcgaacgc cgcttcgcgg
    14341 ttggtccgcc gcagcgcgat gacccagtcc aggtagtctt tgccttcgag aaaggtttgt
    14401 tcgagctgtt gcaggtactc acgctgcacc ggatggttcc cgactctggc gcggagccgg
    14461 atcagaatct gttggaattg aaaaacctgc tgccggactt cctcgacatt gctttctttg
    14521 ccggtgatga cgtagccccg tacgtgaagc cggacgagca gggccgcttc ccgcacatcg
    14581 gcggtcaggc ggaggacttc caggctgcgc cccacttcgg cttcagccat gcgcaactgt
    14641 ctcacgaggt tggaacaagc cacggccagc ccgccgatga tgagcacaac gagggcaaac
    14701 ccggccatca ggcgacggct tgtaaagcga aaggcttttt gaagtgttgg cgacatacaa
    14761 gctccgggtc gaaccggccc cgttaccggt caattcagcc gtggaatcct gtccgctcca
    14821 actggttgtc agccaagcct gtcattcata cggaccaaga aagcgttcac cgttgaaatg
    14881 gatgatgtga cttggcgctt ccgcgaccca aacctctgtc tcccacgcga tttcggaaag
    14941 atacctggcc atcgcccgac gggtaaggaa cgcggtgacg aagaccaggc cagccgtggc
    15001 tcctttgaac agccccctga gttcgttctg acgcttgacg ttgatgggac catgactggt
    15061 gacggcctcg atgaggacaa gccaatgctt ctccggcaaa tgaacgataa cgtctggcat
    15121 tttgccatgt tcatcaaaca ccacgccgag cttcgtgaga tagtctgtct ccaggtgtcg
    15181 ctgtttcctg ccggtgtcgc ccacatagac cagcacgccg ccgggcgtga agcgcgggca
    15241 aaactcttcc acgatcttct tcaccaaccg gttttgtcca ccggccgtga ggtcaagctg
    15301 tcggccatcg ggtagcctga ccggaatcaa tggtatcgcc cgctctcctg gctgtaaccg
    15361 acggagcgcc tctgcgctgt tcacgaagtt cctgagtgac tcgttccagg aagctgtgcc
    15421 gtatgctctg acaatttcca acagtgccgg cgtgacttgg tagcaggtgt caggactgtt
    15481 caccggacgg gcagggttgt cagggtttgc cagaaccagg cccgtttgga cgaattggtg
    15541 aacggtgaag cgccggacgg tttcgcgggt gttcggggca tactttttgc cgaagtgctt
    15601 catcatttca ttgatgccaa ggcatggatt cgccgcctga atccagtcct tctgtggcgt
    15661 cagtccgagc aacgcgagga gggtcagcgc cgaccgcttg ttttgctgtt tttggggaac
    15721 atccagcgcc cggaggatgt ccagtgcctc cgatactctg tcggccgcct gagtctcggc
    15781 ccggtcagcc atggctcacc atctccgcca ccaggcggtc aacctccgcc tggtcgggaa
    15841 aggtttggcc gatgcgctgg ccaatccgca ccagtttgtc tcttgccggg tagcgcagtg
    15901 agcggagatc ggtggcattg acctgggtat gaccgctgaa ctggcgaaag taagcatcta
    15961 caagggtcga attgagaaac gtagcaagcc ctttggccag gttcactggc aaaccagcgc
    16021 ctcgtacgtg gtaaaagttc agatggttct cgaaggcgac ctgttctgct ggaggaagac
    16081 gcagagggtc atagatgccg gccacaaccc gacgccgttc ttccttggct gaaaaccttt
    16141 tgacgagcac atagcagcct ttcgggacaa gcagcttctg cgctcccagg ccgagcgcaa
    16201 gggcgttcgg tttgcgcgcc tggcggtcag gccacccgac aaaaccacgt tgcaggtggc
    16261 agggatagat gagcggcacg gtgttcggcc ctggctggag acagagaagg tgactggccc
    16321 tgaagtccac caccctcccg gtggataccg ccaggcccag ctcttccagg gtgcattcga
    16381 gttccagcat ccggcggcgg acgcattgcc cgtccgtgtc cgggacgacg tggatgaaga
    16441 gatgcggatc gcccggccgg acgagatcgg cgtgttttac ggtttgaatg tgccggttgg
    16501 catccttcgg gtcgggactg ccggatacca ccacgtcatc cgttccgtcg gcggccttca
    16561 cggcccggaa aatgatgttt tcctgtaaaa cctcgtcgtc ggcaaaggcg cgatcacgcc
    16621 ggtcaaacac atgaatgcgg cggaagcgca tctccttcag gaaaaaacgg cggaagggtt
    16681 caaagtaagg gccattgcag aaacttctgg gcgtaatggc aacgatttca ccccccggcg
    16741 caagcagggt cgtggcgacg gccaggaaac cggtgtacag gttgcttgtt tccacgccaa
    16801 ttgcacgcag aagctggcgg tcgcgcgagt gcgaacgaat cttccggtag ggcggattga
    16861 ggatggcaca gtcgaagcgt tcacctgccc ccggcgtgaa gagatcgcca gtgaatgttc
    16921 ccggcccggc ttcgagaaaa ttcccctcaa cgatccgggc gtcgaaatga atacccgctg
    16981 cgcggctggc tgcctgacaa agatcaagcg tcgtttggag ataaggaatc agcctggaat
    17041 cgatctcaaa ggccgtaatg gagatggcat gcggacggcg ctcccggcga gccattgcgg
    17101 tcacaaaggc tgcggaaagg gaaccgatcc cggcaccggc atccagtacc cgaagtgccg
    17161 gctggcgcgc ctcgaagctc tctgccatga acagggcgat gggggccggt gtgaagaatt
    17221 gtcccaaaag ggcgcggtga tgccttccca tgtgttccga gaggccgcgc cgcgttttct
    17281 ccaccgtctc cagaagacca aggcccacgt gcccgccctc ctgttcccaa ggtgtcgtgc
    17341 tggccctttg catcacggtt ctgtgcctgt agatttggct tttgacaacc atcctgtcca
    17401 accggctaac atagtcgtcc cgttcatctg ccccggatga tgatattcca tattgctatg
    17461 cgctatatcc catgtggcct tccggcggtg gtgttgagcc gggttgccgt atcctgacac
    17521 gtccatgctg agccgggttg ccgattccat cttctggatg agccgctaca tcgaacgggc
    17581 ggaaaacatt gcccgcttcg tggatgccac catgacgctg accctcgacc tgccggccga
    17641 tgacaccgcc gcctgggtcg aactcgtcgc cagtgtgggc gaccccgtgg acttcgccgc
    17701 acgctacggc actccaaccc cggcggccgt gctgcgctac ctgaccttcg acgaacaaaa
    17761 tcccaactcc attctgacca cgctggcgcg ggcgcgggaa aatgcccgct gtgtgcgcga
    17821 caccatttcc tcggaaatgt gggagcaggc caaccggttc tacctcgatg tcaaaagtgc
    17881 cgccacccag gggcggttcg gcgccatgcc gcatgccttt ttcacccagg tgaagatgtc
    17941 cagccacctg ttcgttggtg tgacggattc aacgatgtcc cacggcgaag cctggcactt
    18001 caaccggatt ggacggctgc tcgaacgcgc cgacaaaaca gcctgcattc tgggcgtcga
    18061 acgcttcaac gccacaaccc tcgccggcag ttccctcata gacgatctgc actggtcggg
    18121 cctgctcaag tccgccagcg cccacgagat gtatcgcaaa cgattcggcc gcatcgaacc
    18181 gcgccgggtc tttgaattcc tgttgctgag ccgggagttc ccacgggcgg cgcactactg
    18241 cctgctgcgc tgcgtggaat ccgtgcatgc catttccggc accctgcccg gcacctacac
    18301 caacctgccc gaacagcggt tgggacggct ggcagcgcag ctcgactacg ccggcgtcga
    18361 ggatattctt ccgccggagt cgccccacga tgcccgtccg tttctgaacc gctttcggcg
    18421 cgacctctac gccgccggcg atgccattgc catgacgttt ttccccaact gaaggattgt
    18481 gcctatgacc ttttgtctcg gtatcaagac ggtggaagga ctgatcgccg tcgccgacac
    18541 gcgcattacc tccggaaccg agtgccgtac ctcgcgcaag ctgaccgttc accgcgccgc
    18601 cgccgccccg gtctttgtca tgacatcggg cctgcgttcc gcacgcgaca aggtggtgac
    18661 gtattttgac gaatggctgc gcggcgaaac cgtcctgcac cgccggctgt atgaactcgt
    18721 caacgcctat ggcgaacagg tacggcgggt cgtgcgtgaa gaccatgcca tgctggagcg
    18781 cgacggcctg cgctttgacc tcttttccat cattggcggg cggctgcctg acgacggcga
    18841 acaccggctg tttctggtct atccccaggc caactgggtc gaaatcggcg agtcgtcccc
    18901 ctatgccatc attggcaatg ccttctacgg caagcccatt ctggaccgga tgctggacta
    18961 cggctgttcc cttgaagtcg ccctcaaggc ggcgctgctg gcgtttgact gtacgttgac
    19021 gagcgccagc gatgtgagct atccgctgga tgtcgccgtc ctgcgcgccg gggcttccga
    19081 ctttctcgaa catcgcttca ccgagccgga catggcaagc tatgccgtct ggtggcgcac
    19141 caacctccgc cgtctcgtca ctgacgcccc cggaagctgg ctgaccttcc tcaacctgga
    19201 gtctggctta tgagttcgct cgatctggac accatcgcga cgctcaagtc cctcgatgac
    19261 ggcgacggct tttttgccga catggtgaac acatttctcg acaatgccaa agggaccttc
    19321 gagcaactcc acgccgccca tgtagcggac gacatccgcg ctctggagcg ggcagcacat
    19381 aagttgcgtg gcgctgccag cacaattgga gcgcagaatc tcatggccat gtgcgaagct
    19441 ctggaaacgt ccgcccgtac ggggcatgtc ccggatgtgg ccggctcggt tgccgctatt
    19501 gaaactgaac ttcagcatgt ccgcctggcg ctccaggccg aaatgcaaaa ctgaaaccct
    19561 ccccacccgc aaggagaatc gcatgccccc cattgtggac atcggtgaag tgttgcaggg
    19621 ccaggtggcg atcgtgaccg gcgccagctc cggcattggc gccgccgtgg cgcgtgaact
    19681 ggcccgggcc ggcgcggctg tggccgtcaa ctacgccgga aacccggccg gcgcacagtc
    19741 ggtggccgac gccatcacgg gcgctggcgg tcgggccatc atcgtccggg ccgatgtcag
    19801 catcgaagcg gaagtgacgg ccatgttttc cgccgtactg gacgccttcg gacggcttga
    19861 catcctcgtt ggcaacgccg gtctgcaacg cgatgcgcct ttcgtggaga tgacgctcga
    19921 agcctgggag cgcgtcatcg ccgtcaacct gacagggcag tttctgtgca cccgcgcggc
    19981 cgtccggcag tttctcgccc aggaagcccg cccggaggtg tcgtccgccc tgggcaaaat
    20041 catctgcata tccagcgttc acgatgtcat tccctgggcc gggcatatca actatgccgc
    20101 ctcgaaaggc ggtctgtcgc tgctcgtgaa atcgctggcg caggaagtgg ctgagaagaa
    20161 gattcgcgtc aatgccgtct cacccggcgc cattcggacg cccatcaatc gggccgcatg
    20221 ggagacgccg gaagccgagg cggccctgct caaactcatc ccctacgaac gggtgggcga
    20281 gccggaagac atcgggcgtg cggttgtctg gctggcgtcg gatgcttcgg actacatcac
    20341 cggcgcgaca ctctacgtgg acggcggcat gacgctctac ccggagtttc gtgaaggcgg
    20401 ctgatgaccg actggatgtt ttcagaagcc gaacgggcgg ccgtctatcg ggccatccac
    20461 acccggcggg acattcgctc gacctttctg ccgcaaccca tccccgatgc cgtcctgtgg
    20521 cggctgctcg gcgcggccgc cgcggcgcca tccgtgggct tcatgcagcc gacggagatc
    20581 atcgtcatcc gggatgcgga agtacggcgg cagattcacg cgcactttga aggcgtcaac
    20641 cgggctgcgg ctgaagttta cgcggacgct gaccgccgcg cctacgatgc cctcaagctg
    20701 gccgccattg tcgaaacacc gctcaacctg tgcttcacct gcgacacgac gacccggcgc
    20761 gggcgcggtc tgggacgcca gaccatgccc gaaacggccg tgttctcgac ggtctgcgcc
    20821 gtgcagaacg tctggctggc agcgcgcgcc gaaaacatcg gcgtcggctg ggtcagcatc
    20881 cttgagccgg aaacggtcaa aacccggctc gatattccgg cgcacctgac gctggtggcc
    20941 tacctgtgcg tcgggtacgt cagcgacttt ccctcccaac ccgaactcga aaccaaaggc
    21001 tgggaacacg cgcgcgatct gaccgagatg gtgcatttcg accgctacgg cgttcgccgg
    21061 ccgtgaacct ctgactcccc ccacgacaac ttctgacact tctgtacaga acacgactga
    21121 ccatgaaacc aagctctcat gccagttcac cggcgcgcgt ccggtggtgg atcgccctgt
    21181 ggattgccgc tctgttgacc gcgacaccac tggtgcgggc acagcagaca gcggccaaac
    21241 cggccgccgg tgacaaaccg gaagccaagg ccgaggccta tacccaactc aagtaccgcc
    21301 tgatcggccc ctttcgcggt ggacgggtgg gcgccgtgac cggcgtcccc ggacagccaa
    21361 acctgtacta ctttggcgct accggcggcg gtgtgtggaa gacgaccgat ggcggcgtca
    21421 actggcagcc gcttggggac ggcacgttcc gcaccggctc cgtcggagcc attgccgttg
    21481 cccccggtga tcccaacgtt atgtacgtcg gcatggggga acacacctgg cgcggcaatg
    21541 tctcgcacgg cgacggcgtt tacaaatcca cggacgccgg tcggacgtgg cggcgcgttg
    21601 ggctggaaaa cacgcgccac attgcgcgga ttcgcatcca tccgaccaac ccggaaattg
    21661 tctatgtggc cgccatggga cactgtttcg ggcccaacgc cgaacgtggc gtctatcgtt
    21721 cgaccgacgg cggcaggacc tggcagcgcg tgctctttgt cagcgaccgc gcgggctgcg
    21781 ccgatctggc gatggacccg acgaacccgc gcatcctcta cg
//
