LOCUS       NZ_CP072647            21980 bp    DNA     circular CON 02-DEC-2024
DEFINITION  Chloracidobacterium sp. MS 40/45 chromosome 2, complete sequence.
ACCESSION   NZ_CP072647
VERSION     NZ_CP072647.1
KEYWORDS    RefSeq.
SOURCE      Chloracidobacterium sp. MS 40/45
  ORGANISM  Chloracidobacterium sp. MS 40/45
            Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia;
            Terriglobales; Acidobacteriaceae; Chloracidobacterium;
            Chloracidobacterium aggregatum.
REFERENCE   1  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Genomic and phenotypic characterization of Chloracidobacterium
            isolates provides evidence for multiple species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2021) Department of Biological Sciences, Tokyo
            Metropolitan University, 1-1, Minami-Osawa, Hachioji, Tokyo 1920397,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu 1.8 assembler v. 1.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018304805.1-RS_2024_12_02
            Annotation Date                   :: 12/02/2024 00:41:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,029
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,951
            CDSs (with protein)               :: 2,951
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 7 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 197862
            Orig. end                         :: 219842
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072647.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21980
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21980
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21980
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11980](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11980
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(900..910)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(1065..1078)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.24"
                     /tool="antismash"
     misc_feature    complement(2708..2721)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    4636..4647
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.79"
                     /tool="antismash"
     gene            5028..5960
                     /gene="chlG"
                     /locus_tag="J8C02_RS11935"
                     /old_locus_tag="J8C02_11935"
     CDS             5028..5960
                     /EC_number="2.5.1.62"
                     /codon_start=1
                     /gene="chlG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100783.1"
                     /locus_tag="J8C02_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11935"
                     /product="chlorophyll synthase ChlG"
                     /protein_id="WP_246604713.1"
                     /sec_met_domain="ubiA (E-value: 3.4e-21, bitscore: 71.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEGIAPSSLPLSRATPRTASPARHKVSAWVELLKPVTWIPVMCA
                     YVAGALCSAAFTVASLADWRLWLGLLMSGPLISGTCQAMNDYFDRDVDAINEPYRPIPS
                     GRIGLREATLGISLLCALTLLTAYLIHPWIVALALIGIVNAHLYSAKPIKLKRIVWVGN
                     ATVAASYILLPWMSGELAFKGHISWTATAIAVCYVIASIGSMTTNDFKSLEGDARMEIH
                     TLPQVFGVARGAWLGIFVLDAGQLAAAGLLALLGEWLWAALVGATVLPQMWFQRTFLAD
                     PIHKAIWYNAHAQGFLVLGMFLAAWAVRA"
     gene            complement(5967..7532)
                     /locus_tag="J8C02_RS11940"
                     /old_locus_tag="J8C02_11940"
     CDS             complement(5967..7532)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017085.5"
                     /locus_tag="J8C02_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11940"
                     /product="CYTH and CHAD domain-containing protein"
                     /protein_id="WP_211427508.1"
                     /transl_table=11
                     /translation="MGRSVNAPEVATAAAPVEIEIKLALSPRLMPRFRRHPLLRQAARS
                     RAKLYTLYVDTPDVALLRQGIALRLRRSGRRWLQTLKAGAGSSGLLAERPEWEMPVSGK
                     RLKLDLLPAEARSLLPPEAAASLAPCFETEVWRDTWQLNHEGALIEVALDRGEVRAGAR
                     VCPVAEVELELRSGDLPPLFDIAEHLAADLPFQLEPRSKAQRGYQLVGALPCTPVKASP
                     PLLLLDAPASVSFQHIVRSCLRQFEANLPGLLSTSDPDPEFIHQMRVALRRMRAAIGLL
                     RFMGYAKPDWLGELKWLMGELSVARDWDVLVTETLPRIQAHLPQPERLAVLLEAAEAQR
                     RAANDRARAVVTSPRLVPLWLKVERELALLPVSPATTADWSRAALRRRRCQLVRLGARL
                     HELDATERHAMRIAAKKLRYSAEFFAVWHPKAARRFIRHLADLQDVLGVLNDAAVTARL
                     LSELAPAGEAASREAVGLVMGFLACEQAYRLARLEQLWREFHDIPPYWKKGKPPLPADV
                     HAEG"
     gene            complement(7543..8562)
                     /locus_tag="J8C02_RS11945"
                     /old_locus_tag="J8C02_11945"
     CDS             complement(7543..8562)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013901322.1"
                     /locus_tag="J8C02_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11945"
                     /product="fatty acid desaturase family protein"
                     /protein_id="WP_211427509.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 6.9e-10,
                     bitscore: 33.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MECRLTMVVGERGEEFRQTGRRPLLAPAVVKQLSALSPLRATSSL
                     LLDWGIIVGLVTATVWLNHPLLWCLAPLGIAAAQHGLAILAHQAAHYRMYETRWLNDAV
                     GMLCAAPLGVSMHTYRIIHRIHHNHLYSPVDPDMALMAGYPRGRWHLLKKFIRDLLGIT
                     AVKNYLYFFGRPLRRTAPEKPAAHVSIVDDTSENLRRAARRDRRFVIVFHVTLLVAAVA
                     GGWWQSYVVLWLLPLVTLLQWLLRLRALCEHGAVADTSTPLRAARTNLVPWYIRWWLFP
                     HQMHYHIEHHLYPSVPHYRLPACHAALREAGALADAEVSSSLRATWRKFYAPAARPTA"
     gene            complement(8584..9780)
                     /locus_tag="J8C02_RS11950"
                     /old_locus_tag="J8C02_11950"
     CDS             complement(8584..9780)
                     /EC_number="1.17.7.4"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100780.1"
                     /locus_tag="J8C02_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11950"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_246604714.1"
                     /transl_table=11
                     /translation="MAIANDAAAPAKRQNPSRSGFGLRAEVHDEIRNDFDSALVQRIKA
                     SGGTHRAGRLTFRLAQEFGFCYGVDHALDLAYETHVRFPDRRVYLTGEIIHNPTVNEQL
                     ARMGYCFLRPGDEVTAEDIVLIPAFGAPTHELERLKSIGCLLVDTTCGSVVHVWKRVEK
                     YAREGFTAIIHGKYDHEETEATRSRTTLYPDGKFLVVRDRAQAQDVCDYILGRGHREAF
                     LARYAAVATPGFDPDRDLQRVGLANQTTMLSSESLEIAEMIRRAIEQRYGPEEVKTRFR
                     SFDTICSATQERQDAILKLIEEPLDLVIVVGGYNSSNTEHLCEIAAERLPTYHINAPEC
                     LVSARAIRHKPAFSKEETTSWDWLPEGPVTIGITAGASTPNKVVGDCIERIVALADVG"
     misc_feature    9915..9929
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            10001..11980
                     /gene="shc"
                     /locus_tag="J8C02_RS11955"
                     /old_locus_tag="J8C02_11955"
     CDS             10001..11980
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100779.1"
                     /locus_tag="J8C02_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11955"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_211427511.1"
                     /sec_met_domain="T2TS (E-value: 4.6e-145, bitscore: 479.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGFAPRFVQPVVESPLPPAFRPARPAPATAAAVEAAIRKAQAYL
                     LSRQYPEGYWWAELEANVTLTAEYVFLHKVLGTDGERTRQFEKIRTYLRRQQREHGGWE
                     LYYGDGGELSTSIEAYFALKLLGDSPDLPHMARARQFILARGGITKARVFTKIHLALFG
                     AFPWEGCPTLPPWIMLLPDWFPFTIYELASWARSSTVPLLLVSDRKPVVRVPGGDADEL
                     YAEGRAQADLSLPNPAGPLSLGGVFIGFDRMLKLMERFDFSPRKAEALARAEQWTLDHQ
                     DDSGDWGGIIPAMLNSLLGLHCRGYAPTHPAMQKGIAAVERFCIETEDEFHTQPCVSPV
                     WDTGLTILALLDSGLPNDHPALVRAGEWLLSKQIFRDGDWRFKNRTGPAGGWAFEFWND
                     FFPDVDDTAVVTMALHRLKLPDEAEKQSRLKLAIEWTLSMQSKNGGWGAFDVDNTLEIL
                     NDIPYGDLKAMIDPPTADLTGHILEMLGVTGYAAPREKVERAIAFIKSKQEPEGCWWGR
                     WGVNYIYGTHMVICGLVALGLDPREAFIMRGTQWLNSCQNEDGGWGETCASYGDRTLMG
                     VGKSTPSQTAWALLGLIAGGEGKSDCARRGIEYLVTHQNDDGSWTEAEFTGTGFPNHFY
                     MNYHFYRNYFPLMALGRYRTFARA"
     gene            12153..12908
                     /locus_tag="J8C02_RS11960"
                     /old_locus_tag="J8C02_11960"
     CDS             12153..12908
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.5"
                     /locus_tag="J8C02_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11960"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_058865781.1"
                     /transl_table=11
                     /translation="MSTYTNGHVPDYRVAVIDELNHAAKAVEKYGLPVTATYTLEEAGT
                     RLSELGRYQIIIVGVSLFPIRRRIVNELRRVAPDACLVFLRRAHEFSNGQSPLEVKNTV
                     SADFMLSASSPDEVWLAAQSLKHMFPLPTTADLEPPAEAFLMDRVMKVVAAHYQDPNLN
                     LRAVASRLNLSSGQLSRLLNRHAGMRFRQLLQQTRLEAAKQLLMTANCTTIKEVAFKVG
                     FADSDYFSRAFKRYTGCCATEYRENSALQ"
     gene            complement(12969..15116)
                     /locus_tag="J8C02_RS11965"
                     /old_locus_tag="J8C02_11965"
     CDS             complement(12969..15116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019853459.1"
                     /locus_tag="J8C02_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11965"
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_211427512.1"
                     /transl_table=11
                     /translation="MMKLVSIVLAVALVCPGLFSLPPAPAGDAAGDAPGRPGVRSTWTS
                     GGKLGVGTAVSRRSRVWFTLGATGLTEVYYPTVDMPNLRALDFVIVGNGYVGCASRDAL
                     ERETRRTRDDALSFAQTMSDGRRWRIGQRYACDPDRDALLIEVEVTALDGGNYEVFALL
                     DPAVANSGMGDTGEHRGRTLVASDRDATTNQTIAMAFAAQPAFEVVSSGFAGVSDGWTD
                     LAADGRLDGREQRAVDGNVVQIGQLSAPRTTLALAFADRPETAANVAAAALAEGFAAIA
                     GRYEAEWQSFTARLPRVAPEYRAQFAVAAMTLLAHEDKTYPGAGVASLSIPWGEAADAD
                     RPTSGGYHLVWSRDLYHVATAWLALGDRDAAGRALDYLFKVQQNADGSFPQNSWLDGRP
                     YWPSVQLDEVAYPIILAWQLERFDRQTYTQHVRPAAEYILRHGPYTPQERWEEEEGYSP
                     STIAAEIAGLICAADIARRLGRAEDAERYERTADRWAEGVQQWCYTTTGPWDEGEAERG
                     YYLRINNNRDPNDGFRLDINNGGGQHDERAIVDAGFLELVRLGIVPPDDPQIVRSLRIV
                     DRVIRVETPMGPGWRRYNHDGYGERADGGGWQDKGIGRIWPLLTGERGEYVIASGGDAS
                     AYAKTMLAFAGPAGMIPEQVWDQAYPPDARYRIGHGTGSATPLAWSMAQFVRLVMGIEA
                     RRVVEQPAVVFQRYAGKKRPR"
     gene            complement(15141..17006)
                     /locus_tag="J8C02_RS11970"
                     /old_locus_tag="J8C02_11970"
     CDS             complement(15141..17006)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012356.5"
                     /locus_tag="J8C02_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11970"
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="WP_211427513.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.9e-65, bitscore:
                     217.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRINWLFCAVGGGWWLVWLTVVGLSQVVTKVEPPDWPAVTRPTT
                     IELLVTGENLTGARLVSDTPGITAGRVEVVSSGRYAFCEVTITPEARPGPVQLNLLTPN
                     GARPLPWAVFSPLPRTTAFRGLTPDDVVYLLMIDRFANGDRSNDAPPGMPPANRANPRA
                     YHGGDLRGVIEKLDYLQALGITAIWMTPVYDNADAGEDYHGYGATDFYAVESRFGTLEQ
                     YQTLAQEVRRRGMKLLQDVIPNHTGPQHPWVRRPPTPTWFNGTPEQHLTCNFDIPALTR
                     PDATPHERALVLEGWFAGILPDLNGADEKYQRYAIQNSLWWAEKVGLDGMRLDTYPYVV
                     RPFWRDWQRAMDDAFPNFTAVGEIWHGDPNIIAFFRGGRTGWDGIDTGLRSQFDFPLFY
                     AIRDFAAGNAPASRLAGLLQQDALYGNAHLNVTFIGNHDVPRVMRACGGDWRRVRLALT
                     LLMTLRGIPQLYAGDEIGMDGGEDPDNRRDFPGGFGDTPNAFTPAGRTPDQQKLWEETQ
                     QLLALRRRHRALRHGRHRDLVVEGRQWAFLREDGKERLLVVVNGSGSRAEVPIPAASIC
                     DGAPNRPCTVNPVHSSFPVNDRKMQVRETLRVPVEAFGYRVFRVR"
     gene            complement(17073..20297)
                     /locus_tag="J8C02_RS11975"
                     /old_locus_tag="J8C02_11975"
     CDS             complement(17073..20297)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025006.5"
                     /locus_tag="J8C02_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11975"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_211427514.1"
                     /transl_table=11
                     /translation="MGVLFGFVWPALAQSDTARLTGVITDTSGSVIAGATVTATETATN
                     AKLETTTNADGVYVFPVLKAGTYLIEFSAPNFKKLARPEVVLRVNQVLSLNAELEPGNI
                     TDVVEVTAGAPLVETASSSVGQTITGRQIVDLPINGRNFTQLATLTPGVTRGTPGSNAD
                     GSGGNAETFRQGDTGSAALSVNGLREQNNNFTLDGIDNNESIVNSIVFFPPIEAIEEFR
                     VITSVAPAEFGRGGGAIVSATIRSGSNDFHGSAFEFFRNSAMDARATDLVGFVPPKPVF
                     IRNQFGGTFGGPIVREKTFFFADYQQLRQRLPREEGRTFTVPTARMRQGDFSELLNPNF
                     TGLGAAVQIFDPLTGLPFPGNIIPQNRLDPAAVRYLNFFPLPDLPDRARFNFFNRQLQR
                     QNFKGGDLRLDHRFTERDTVFVRFSIADDPQFDPGRLGINAQTGFGSGTNRQFNHSVMG
                     NYTRTFTPNVVNELRFGYVKQNIEFLPLGFGTDLNRQLGIPGINGITRANGISLIGGGN
                     GDFLEYLGDFGEFILNQRTIQFTDAVTWVTGNHSAKFGASIIQRNIRSVQADFSKGFYF
                     FSDQVVTFRPGGPPPASPGLGQTGYQVAQMLVGRTAFTTTANPEIPAATTRSYEMGFFA
                     QDDWRINRRLTLNAGLRYELFTPYYELNNRMANFDPASGRILLAGRDGNSRSLVDTDRN
                     NFAPRIGAAFDLFGNGRTVVRGGWGLFYSLDRGGIANQLTQNPPFIVTQFRFDGPGSNV
                     RLGQPIPPPDPINPASPNLPPGTQIRFTPRNTRNTRVQQFNVTFEHQLTDFLAFHIAYV
                     GTRGDNVTAVTTVGGFGDAEITRRLTTIANVGESRYDSLQIKVNQRSWKGLSYLAAYTF
                     GKATNNSPGPFPGTGGAGRSTPADPGGLAPGLADYDVRHRFTWAFNYDLPFFREAGSRV
                     VRALLYGYQLNAILTLQGGTPFSVFGGDGGRARLVPGQDPNAGRRSAARWFNTDAFAPS
                     ANPSEQYPRNAFLRSPGISTVDGSIFRRFTITERVNLEFRAEAFNLFNKPQLGFPNVFL
                     GGDFGRIFSVRNRSNRSVQLGLRLSF"
     misc_feature    20607..20624
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    complement(20611..20624)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    20861..20875
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    21020..21036
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.39"
                     /tool="antismash"
     misc_feature    21611..21620
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    21697..21710
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.15"
                     /tool="antismash"
     misc_feature    complement(21814..21828)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
ORIGIN
        1 gagccatatc cccgtggaca gttccgtcgt ggctgtcacc agtcccgttc ccacggccgt
       61 tcctgacata gtgctcgaac aacaccttac cgatggcgtc ggggacggaa agcacgcgcg
      121 ccgggccaaa gccggccgaa cgcgaaccgc caatgccgcg aagctgctcg gcaatgagct
      181 tcaccggcac gccacagcgc agggccagcg aaatcaaccg cccgatggct tcggtaaagg
      241 ccgtcacatc actcccggcc cgcccgatga tggcaaagac ttcaaacggt ttcccgtcca
      301 gctcggtgac gaacaaccgc agcttgccaa gcggcgtcat caccggaaac gagtggctgg
      361 gcaagccttc ggccgggacc ggtcgtggtt tcagctcggc cggggttggt tcagccgacg
      421 gggggctggt gcttttgccg gtggaaccgg tggagagcac ctggttgtcc cgtgaaccgt
      481 cgcgatagac ggtgatgccc ttgcacccca gacggaacgc cagctcgtag gcttcacgga
      541 cctgattggg agtcgcctcg tgggggaagt tgatcgtctt cgagatggca ctgtcggtgt
      601 attcctggaa ggccgcctgc atgcgcacat gccactccgg cgcgatgtcg tgggccgtaa
      661 cccacacccg ctgtacctcg gccggcactt ccgggtgatg gatgtgaccg gtatcggcaa
      721 tccgttccat gagttcaggg ctgtaccagc cctcccgtct cgcctgggcc acgaaatcct
      781 gattgatgtc aagcatccgg ctatcggcct ggtagcgcca gaaggcaatg gcaaagagcg
      841 gctcgatgcc cgacgaacag ccggcaatca tgctgatagt gccagtaggg gccacggtgg
      901 tgacattaca gttgcgcagc cggcgtggcg gacgaatccg cgcgccatcc gggcggcggg
      961 cgcaggtcgc gtcgggaccc cagatgctcc gctcccactc ggggaacgcg ccccgctcgc
     1021 gggccaactg ctcggaagcc accttccctt cctcgtcaat aaagtgcatg accttccgcg
     1081 ccaactcgat ggcttcatcc gagttgtacg gaacacccaa ccgcaccagc atgtccgccc
     1141 agcccattac ccccagccca atccgccgga tacgctggct caggtgcgca atctgttcca
     1201 gcgggtagtg attggcatca atcacgttat cgagaaaacg tgtgctttcg tgaaccacct
     1261 cgcgcaggtg attccagtca acggttcgtt cgggcgtgac aaacttgccc agattgatcg
     1321 agccaagatt gcagacatcg tagggcagca acggctgctc tccgcagttg tgcacataaa
     1381 gtccattggc gtcgaaggcg ttgacgcccg ggatggagca gtcgaagacc tcagcctcac
     1441 caatgagcgt caacgactcg acctcggcca caaagcactc acggtagtgg ccgcgggcag
     1501 agcgagcggc gagagcggag ctgagcgcct gagccttggc cgggttggta aaacctacca
     1561 gggaagcgaa ggtcagcagg ttgtccttcg agatgcagag ctcgtgctga gccttcgtgg
     1621 catagagctt cccgccgccg cggccatcgg gcaggacacg ctcgccggcc ggccggcggt
     1681 tgcggtagag gcggctggca atgccaaggc gcagcagcat gcgctggacg cgctccagaa
     1741 gggcgaggtt cgactgggca aggcgaaccg acatgccctt cccgccaccg tccagtacag
     1801 tgccatcggc gtcgaacagg ccacggagca gaccgcggta gaacaggctg gaggcgcgct
     1861 cggtgctgtc tgtgaggctc ttgttctcag gcgtgatgcc gaaagcagca gcaagggcgg
     1921 ccagcgcact ggagcgcacg cggaattcgt tgcgctcctc gatcggctgg atgccaaggt
     1981 cggcgcgcgt tttcaggttg gctttgatgg cacccaatgc ctgctgggcc atatactcag
     2041 cgtcctgccc ccagaaggag aggacggccc ggttctcact gaacgttcca tcaccgacga
     2101 ggagacccag aagccagccc tgctccagcg tgccggcgcc ctcccactgg gtgaactcac
     2161 gatgattgtg aagcttcacc aagtcgcccg gctgaaggcg ctgaacctcg acccactcgg
     2221 tctgctcacc gttgcgctcc acggcgttca cgcgcatcac acggtgatta ccagtcagcc
     2281 ggagcgagta accgctggaa gtcttcagtt catagattgg cttgagtccg ttggaccaga
     2341 agccacgggc gtcgctgcca tacgccattc cgtcaacaat ggctgtaaac ggcatgccga
     2401 ccagttcggc gacctgacgg gggccgtcgc tcgtctgcac ccaggcatca cgggtgatgc
     2461 acggattcgt ggcctcgtac ccgcccaggg acggcaccgg gttgtactcg ttggcccggt
     2521 caatgaaaaa cagtcccggc tcgccagtgg catgcgcgca ctgcacgatc aggtcaaaga
     2581 ccatccgggc gcgcaggcgc atgggttgac cgggcggcac cagtatctcg ccggtcaacg
     2641 ggtgtttcag tccgtcgcgt gaagccatct gcacggcgcg ggtgcgcggg ttgatcagtt
     2701 cataggtttc atcgcgctca acggcgcgca tgaaagcatc ggtgatagcc accgagatgt
     2761 tgaagttcgt gattttcgtc gtatcgcgct tgcaggtaat aaactccaga atatcggggt
     2821 gatcgcagcg cagaataccc atgttcgccc cacggcgcgt tcccccctgc ttaatcgcct
     2881 cggtcgagtg gttatacacc tccataaaac tgaccgggcc gctcgctacg cccatggtgc
     2941 tgcgcaccac gtcgttgcgc gggcgcagcc gcgaaaagct gaagccagtg cccccgccgc
     3001 tctgatgaat cagcgcctga tgcttgaggg tgtcgtaaat gctgttgagg gtatcttcaa
     3061 tggggagcac aaagcagtta tgcaccacca tctggttggc gacgtaggtg tgatcctcct
     3121 cgacctcaaa gttatagacg atcgcctctt catcaagcgc ggcgacttca aggacccgat
     3181 aggcgccgtc gcggaccatc ccggcgttgt acgtttcgcc ataggccagc gaccaaggct
     3241 gcacggtgcc gagggctggc agcgaatctg cccgtagcgt cgggtagtag cccaggctgt
     3301 aggccaaggt gaagagctgg cggaccagca cctcattgca gagggtgatc cgggtctgat
     3361 ggctgttgat cggggtgccg tcgccgtcgg cgacaccctg gagcagcgcc tggcgaagat
     3421 cgggcgacag gctcatggcc caggcgggca gccgcttctg gtcgaagccg gcgccgaaat
     3481 gctcgacgag ccactgcgca agcagcttgc tctggaggcg cacggtcgtc cagccatcgc
     3541 cccgccggcc ttgcggctgg gtgcttttct gcacacgggc gggcaggccg agtttaccct
     3601 caaggatcgc ggcgaggcgt gcggcgtgct catcctcatc ccaggagagc gtgaagcgga
     3661 tatcgtaccc ggccgagatg gacccttccg cgaggtagag gcccagcatc caggcgagag
     3721 ccgcatcaat tgtgacgccg tcgcggatcg gagcgacctg gcgcgagatc gcatcacgct
     3781 gggcgtagcg gcgctgtgag cgtgggctgg tgccctcaag ccgggcatgg acccagccat
     3841 cctcaacgtg gccgtcaaaa tgcatcgtga cggttgcgct cccgatctct gggcagccga
     3901 tcttcacgaa gtgctgtttg ggtgccagat ccctgacctg cacccagcca tcggtcgtga
     3961 ggaagggatg ctcggcggtg acataaagcg ccggcaactt atcaaccttc acccggtaga
     4021 ggcagccggt gcggcgcatc gtcccggtga cgggacggta gcggccggcg tgggtaagca
     4081 caagggtgcc gacctgcacc tcctcgatgg gctgcggccc agcgatcgtc tcgatcatcg
     4141 taccggcggc gaagcacgcg ctgagctgtc ccaagggtcg cccggcgttc atcagggtcg
     4201 ggctgttcgg ctcaaaccag ccctgcgcca tcagttcgta aaaacgttcg gcacgttctg
     4261 caacctgccc ggccgatgcc ccatagcggg catcaactgc agcaatagtt ttagctaccc
     4321 gccagaacat ggcttcgggg gtttcaatca cctcgccctg ctcgttctta agcagatagc
     4381 gtttcatcag gaccgtacgg gcgatgtcgg tgagactggc gggggcaggt tcctgtttca
     4441 tcatggatcg taaaactcct tggctggaca gagggacaaa gcgtgccggt atgcacggct
     4501 ggaaagcgaa aatcagacag aaccactata tctggtagcg gcgatggttg gtagggtaca
     4561 catcttgatt ctgcgcgcgg ccctgccagt gccgcccaag ggcgggcacc gcctgcttgc
     4621 ccgcagcttt tcgccgaaaa agtattcacc gggtgtctgt ggctccggtg cgcagatagg
     4681 ctttctcagg caggcagcct acggtgccac atccacgtgc ggacaggttg ggtcatcatg
     4741 aaccgtcccg tcagacttac ccgttcctgc ccaatcagga acgtgaagga caccacacgc
     4801 cggacacggc caccggcaac acccactgcc cggttgaggc ttcaaccggc cgcgctgaca
     4861 agatttctcc acgccgggta catccgggga actatcaggc agcatccgaa gcgcccgggc
     4921 cagccacgcc gccggacacc agccatcgag aaaatgggtt ttgcatccgc cggacgattc
     4981 cataagttgg aaataacgcc atggaagggt tgaggaaacg tctggccgtg aaagaaggta
     5041 ttgcaccatc atcgcttccg ctgtcacggg cgacacctcg caccgccagt ccggcgcgcc
     5101 acaaggtctc ggcatgggtc gagttgctca agcctgtcac ctggattccc gtcatgtgcg
     5161 cctacgtcgc tggcgccctg tgcagcgctg cgttcaccgt ggcgagcctc gccgactggc
     5221 ggctgtggct gggactgctg atgagcgggc cgctcatttc cggcacctgc caggccatga
     5281 acgactactt cgaccgcgac gtggatgcca tcaacgaacc ctaccggccc atcccttccg
     5341 gccggattgg gctgcgcgaa gccacgctgg gcatcagcct gctgtgcgcc ctcacccttc
     5401 tgacggccta cctcatccat ccgtggattg tggcgctggc gctcatcggt atcgtcaacg
     5461 ctcacctcta cagcgccaaa cccatcaagc tgaagcgcat cgtgtgggtc ggcaatgcca
     5521 cggttgcggc ttcgtacatc ctgcttccct ggatgtcggg cgagctggcc ttcaagggcc
     5581 acatcagttg gacggccact gccatcgccg tctgctacgt cattgccagc atcggcagca
     5641 tgacgaccaa tgatttcaag tcgctcgaag gcgatgcgcg gatggaaatc cacaccctgc
     5701 cccaggtctt tggggtggcg cggggagcct ggctgggcat tttcgtgctg gacgccggac
     5761 aactcgccgc cgccggactg ctggcactgc tgggtgaatg gctgtgggca gcgctggtgg
     5821 gcgctacggt actgccgcag atgtggtttc agcgcacatt tctggccgat cccatccaca
     5881 aggccatctg gtacaacgcc cacgcccagg gctttctcgt gctggggatg ttccttgccg
     5941 cctgggccgt ccgcgcctga cagccgtcag ccttctgcgt gaacatccgc cggaagggga
     6001 ggtttgcctt ttttccagta gggcgggatg tcgtggaact cgcgccagag ctgctccagc
     6061 ctggccaaac ggtaggcctg ctcacaggcc agaaagccca tgaccaggcc cacggcttcc
     6121 cggctggcag cctcgccggc cggagcaagc tcggacagca ggcgcgccgt cacggcggcg
     6181 tcattgagta cgcccagcac gtcctgcagg tcggccaggt gccggatgaa gcgccgggcc
     6241 gccttgggat gccagacggc aaaaaattcc gcgctgtagc ggagtttttt ggccgcaatc
     6301 cgcatggcat ggcgttcagt ggcatccagc tcgtgcaacc gcgcacccag gcgtaccaac
     6361 tggcaccgcc ggcggcgcag ggccgcccgc gaccagtcgg ccgtcgtggc cggcgagacg
     6421 ggcagcagcg ccaactcgcg ctcaaccttc agccacaacg gtaccagacg cggcgatgtc
     6481 accactgcgc gcgcccggtc attggccgcc cggcgctgcg cttcggcagc ttcaagcagg
     6541 acggccagcc gttccggttg cggaagatgc gcctgaatcc ggggcagggt ttccgtcacc
     6601 agcacgtccc agtcacgcgc tacggacagt tcgcccatca gccacttgag ttcgccaagc
     6661 cagtccggct tggcatagcc catgaagcgc agcaggccga tggccgcccg catacggcgc
     6721 agggcaaccc gcatctggtg aatgaattcg gggtcgggat cggacgtgct gagcaggccc
     6781 ggcagattgg cttcaaactg gcgcaggcaa ctccgtacga tgtgctgaaa cgacacactg
     6841 gccggagcat cgagcagcag gagcggcggg ctggccttga ccggcgtaca gggcaatgca
     6901 cccacgagct ggtagccacg ctgcgctttg ctgcgcggtt cgagctggaa cggcaggtcg
     6961 gcggccaggt gttcggcgat gtcgaacaac ggtggcaggt cgccgctcct gagttccagt
     7021 tcgacttcgg caacggggca gacccgtgct ccggcgcgta cttcaccgcg atccagggcg
     7081 acttcaatga gagcgccctc gtggttgagt tgccaggtgt cgcgccagac ttctgtctcg
     7141 aaacagggcg caaggctggc ggcagcctcc ggcgggagca gcgaccgggc ttcagcaggc
     7201 agcaggtcca acttcaggcg tttgccggaa accggcatct cccactccgg gcgttcggca
     7261 agcagcccac tgctgccagc ccccgccttc agggtttgca gccagcggcg tccgctgcgg
     7321 cgcaggcgca gggcgatacc ctggcggagc agggcaacat ccggggtgtc cacatacagg
     7381 gtgtagagtt tggcgcgtga ccgcgccgcc tggcgcagaa ggggatgccg tctgaagcgg
     7441 ggcatcagcc tgggcgagag cgccagtttg atttcgattt cgaccggagc agccgccgtg
     7501 gcgacctccg gtgcattgac tgacctaccc ataagcacgg cttcacgccg tcggccgggc
     7561 agccggcgca taaaacttcc gccacgtagc acgcagtgac gacgacactt cagcgtcggc
     7621 cagcgcgccg gcttcccgca atgccgcatg acaggccggc agccggtagt gcggcacgct
     7681 gggatacagg tgatgttcga tgtgatagtg catctggtgc gggaaaagcc accagcggat
     7741 gtaccacggc acaaggttcg tgcgcgccgc gcgcaacggc gttgaagtgt ccgctaccgc
     7801 gccatgttca cagagcgcgc gcagccgcaa cagccactga agcagcgtca ccagcggcaa
     7861 aagccataaa acgacataac tctgccacca cccaccagca acagccgcca caagcagcgt
     7921 cacatggaag acaatgacaa aacgccgatc ccgacgggcc gcccgccgca ggttctccga
     7981 agtgtcatcc actatggaca catgtgccgc cggcttttcc ggcgcggtgc ggcgcagcgg
     8041 ccgaccgaaa aagtacaggt agtttttgac cgccgtaatc cccagcaggt ccctgatgaa
     8101 ctttttgagc aggtgccagc gcccacgggg ataccccgcc atcagcgcca tgtccgggtc
     8161 aaccgggctg tacagatggt tgtggtgaat ccggtgaatg atgcggtacg tgtgcatgga
     8221 aacccccagc ggagcagcgc acagcatgcc aaccgcatcg ttgagccatc gggtttcata
     8281 catccggtag tgcgccgcct ggtgggccag aatggccagc ccgtgctgcg ccgccgcgat
     8341 acccaggggt gccaggcacc acaacagcgg atggttgagc cagaccgttg cggtgacaag
     8401 accgacgatg ataccccagt caagaagcag cgaagacgtt gcccgcagcg gcgagagcgc
     8461 cgaaagctgt ttgaccacag ccggcgccag cagtggccgc cggcccgtct ggcggaattc
     8521 ctcgccccgt tctcccacaa ccatcgtcaa ccgacactcc atgctaatct gaccggggga
     8581 cgctcagccc acgtcggcca gcgccacgat gcgttcgata caatccccga caaccttgtt
     8641 gggcgtcgaa gccccggccg tgatgccaat ggtgacaggc ccttccggga gccagtccca
     8701 cgaagtcgtc tcttccttgc tgaaagccgg cttgtggcgg attgcccttg ccgataccag
     8761 acactccggc gcgttgatgt gataggtcgg caaccgctct gcggcaattt cacacaggtg
     8821 ctcggtgttg ctgctgttgt agccgcccac cacaatgacc agatcaagcg gttcttcaat
     8881 gagcttcagg atggcatcct gccgttcctg ggtggcgctg cagatggtat caaacgaacg
     8941 aaagcgtgtt ttgacttctt ccggcccgta ccgctgttcg atggcgcgcc gaatcatctc
     9001 cgcaatttcc aaggattcac tcgaaagcat cgtcgtctgg ttggccagcc cgacacgctg
     9061 caagtcgcgg tccgggtcaa aacccggcgt cgccacggcg gcatacctgg ccaggaaggc
     9121 ttcgcggtgg ccgcgcccaa ggatgtaatc acacacatcc tgcgcctgtg cccggtcgcg
     9181 cacgacgaga aacttgccgt cgggatagag tgtcgtccgc gagcgcgtgg cctcggtttc
     9241 ctcgtggtcg tacttgccgt gaatgatggc cgtaaagcct tcccgcgcat acttttcaac
     9301 ccgcttccag acgtgcacca ccgagccgca ggttgtgtcc accagcaggc agccgatgct
     9361 tttgagacgc tccagttcgt gggtcggcgc accaaaggcc gggatcagga caatgtcctc
     9421 cgccgtcacc tcgtcgcccg gccgcagaaa gcagtagccc atccgggcca actgctcgtt
     9481 gacggtgggg ttgtggatga tttccccggt cagatacacc cgccggtcgg gaaaccgcac
     9541 gtgggtttcg taggccaggt caagggcatg gtcaacgcca tagcagaaac cgaactcctg
     9601 cgcgagacgg aaggtgagac ggcccgcccg gtgcgtccca ccggaagcct tgatgcgctg
     9661 gaccaacgca ctgtcaaagt cgtttcggat ttcatcgtga acttcagcgc gcagaccaaa
     9721 cccgctccgg gaaggatttt gccgttttgc cggcgcagcc gcatcattcg ctattgccat
     9781 gagaaacacc tgtgtattcc gggaagagtc aacgacctta gctgcaagct tacatcgcgc
     9841 tgtaaccatt cgccaagcaa cgccgaaatc actccggcca gtcaccttcc cgcccccggc
     9901 aggtgtagcc tggcttctga ttctgagata gagtcgccga cttcgcgctg gctgcccgac
     9961 agccggcgtc cgtaccctgc ttttccgagg aaccaccgct atgcccggat ttgcgccccg
    10021 ctttgtacaa cctgtcgtcg agtcaccact gccgcccgcc ttccgcccgg cgcggccggc
    10081 gccggccaca gcggccgccg tcgaggcagc catccgcaaa gcgcaagcgt atcttctttc
    10141 caggcagtac ccggaaggct actggtgggc cgaactcgaa gccaacgtca ccctgacggc
    10201 tgagtacgtg tttctccaca aggtgctcgg cacggatggc gaacggacgc ggcagtttga
    10261 gaaaatccgc acctacctgc gccgccagca gcgcgaacac ggcggctggg agctgtacta
    10321 cggcgacggc ggtgaactct ccacgagcat cgaggcctac tttgccctca aactgctcgg
    10381 cgacagcccc gacctgccgc acatggcgcg cgcccggcag ttcattctgg cgcgcggcgg
    10441 catcaccaaa gcgcgggtgt tcaccaaaat ccatctggca ctgttcggcg cgtttccctg
    10501 ggaaggctgc ccgacgcttc cgccgtggat tatgctcctg ccggactggt ttcccttcac
    10561 catttacgaa ctcgccagtt gggcccgcag ctcgacggtt cccctgctcc ttgtcagcga
    10621 ccggaaaccc gtcgtgcgcg taccgggcgg cgatgccgat gagctgtatg ccgaaggccg
    10681 cgcccaggcc gacctgtccc tgcccaatcc cgccggcccc ctgtcgctgg gaggtgtgtt
    10741 catcggcttc gaccggatgc tcaaactcat ggagcggttc gacttctcgc cccgcaaggc
    10801 ggaagccctg gcacgggccg aacagtggac actcgaccac caggacgaca gcggcgactg
    10861 gggcggcatc attccggcca tgctcaactc gctcctgggg ctgcactgcc ggggctatgc
    10921 gccgacccac ccggccatgc agaagggtat cgcggccgtg gagcggttct gtattgagac
    10981 cgaagatgag ttccacacgc agccctgtgt ttctcccgtc tgggacacgg gcctgaccat
    11041 cctcgccctg ctcgattcgg ggctgcccaa cgatcatccg gcgctcgtcc gcgccggtga
    11101 gtggctgctc tccaagcaga ttttccggga cggcgactgg cggttcaaaa accggacggg
    11161 accggccggc ggctgggcct tcgagttctg gaacgatttt ttccccgatg tggacgatac
    11221 ggccgtcgtc accatggcgc tgcaccggct caaacttccc gacgaagccg aaaaacagag
    11281 ccgcctgaaa ctcgccatcg agtggacact ctcgatgcag agcaaaaacg gtggctgggg
    11341 cgcttttgat gtggacaaca ccctcgaaat cctcaacgac atcccgtatg gcgacctcaa
    11401 agccatgatt gacccgccca cggccgatct caccggccat atcctcgaaa tgctgggcgt
    11461 caccggctat gccgcgccac gggagaaggt cgaacgggcc attgccttca tcaaaagcaa
    11521 acaggaaccg gaaggctgtt ggtggggacg ctggggcgtc aactacatct acggcacgca
    11581 catggtcatc tgcggcctgg ttgctctggg gcttgacccc cgcgaagcct tcatcatgcg
    11641 cggtacgcag tggctcaact cctgccagaa cgaagacggc ggctggggcg agacctgcgc
    11701 cagctacggc gaccggaccc tgatgggcgt cggcaaaagc acgccctccc agacagcctg
    11761 ggcgctgctg ggactgatag ccggcggcga aggcaagtcc gactgcgccc gccggggcat
    11821 cgaatacctc gtcacccacc agaatgacga cggaagctgg acggaagccg agtttaccgg
    11881 caccggcttc cccaaccact tctacatgaa ctatcacttc taccggaact acttcccgct
    11941 catggcgctg gggcgctacc ggactttcgc ccgggcctag gccgccaagc tagaaaattc
    12001 gctacacctt ccggtgtaga aaattcttgc ccttctgact ggaacggagt actgtcactg
    12061 ccgttactgg atttttccag tttgccattc cacagtggct tcctgaaaag cttgtgatgt
    12121 cgcattgggc gcggctgccc agggagggag tgatgagcac ctacacgaac ggtcatgttc
    12181 cagattaccg cgtcgccgtc atagatgaac tcaaccatgc ggccaaggcg gtcgagaaat
    12241 acgggctgcc ggtaacggcg acctatacgc tcgaagaagc cgggacgcga ctttccgaac
    12301 tcggcaggta ccagatcatc atcgtcgggg tgtcgctgtt tcccatccgg cggcgaatcg
    12361 tgaatgagct gcggcgggta gcgccggatg cctgtctcgt gttcctgcgg cgcgcccacg
    12421 agttttccaa cgggcagtcg cccctggagg tcaaaaacac ggtctcagcg gacttcatgc
    12481 tgagcgcctc ctcgccggat gaagtctggc tggcagctca gtccctgaag cacatgtttc
    12541 cgctgccgac gaccgccgac ctcgaaccgc cagcggaggc gtttctcatg gaccgggtga
    12601 tgaaggtggt tgctgcacac tatcaggacc cgaacctcaa cctgcgcgcg gtggccagcc
    12661 ggctcaacct ttcttcgggg cagttgtcgc ggctgctcaa ccgccacgcc ggaatgcggt
    12721 tccggcagtt gctccagcag acccgcctcg aagccgccaa gcagttgctg atgacggcca
    12781 actgcacgac catcaaggaa gtggccttca aggtcggctt tgcggacagc gactactttt
    12841 cgcgggcctt caagcggtac acgggctgct gcgccacgga gtaccgcgaa aacagcgccc
    12901 tccagtaaga ccgccagtgt tgatgcgggt gtgcccccaa tgacaggcag ggatggcgtt
    12961 cctgcccgtc agcgggggcg tttctttccg gcgtaccgct gaaagaccac ggccggctgt
    13021 tcgacaaccc gcctggcttc aatacccatc acgagtcgca cgaactgcgc catgctccag
    13081 gcgaggggtg tggcgctgcc ggtgccatga cctatccggt agcgggcgtc gggcgggtat
    13141 gcctggtccc agacctgttc gggaatcatc cccgccgggc cggcaaaggc cagcatggtt
    13201 ttggcgtagg cgctggcatc gccgccgctg gcaatgacgt attcgccccg ctcgccggtc
    13261 agtagcggcc agatacgccc gatgcctttg tcctgccaac cgccgccgtc agcgcgttcg
    13321 ccgtagccat cgtggttgta gcgtcgccaa cccggaccca tgggcgtttc aacccgaatc
    13381 acccggtcaa caatccgcag tgaacgtacg atttggggat cgtcgggcgg tacgatgccc
    13441 aaccgtacga gttccagaaa acccgcatcc acgatggcgc gctcatcgtg ctggccgcct
    13501 ccgttgttga tgtcgagcct gaagccgtcg ttggggtcgc ggttgttatt gatgcgcagg
    13561 tagtaccccc gttcggcttc accttcgtcc cacgggccgg tcgttgtgta gcaccactgc
    13621 tggacgcctt cggcccagcg gtcagccgtg cgctcatagc gttcggcgtc ttcagcgcgg
    13681 cccagccgcc gggcaatgtc tgccgcgcag atcagaccgg cgatttcggc ggctatcgtg
    13741 gaaggggaat agccctcttc ctcctcccac cgctcctgtg gcgtgtaggg gccatggcgc
    13801 aggatgtatt cggcggccgg ccggacgtgc tgggtgtagg tctggcggtc aaagcgttcg
    13861 agttgccagg caagaatgat ggggtaggcc acttcgtcaa gctggacgct cggccagtag
    13921 ggacgcccat ccagccagct attctgcgga aaactgccgt cggcgttctg ctgcaccttg
    13981 aaaaggtagt ccaaggcgcg gccggccgca tcgcggtcgc caagggccag ccaggcggtg
    14041 gcgacgtggt agagatcacg tgaccagacg agatgatagc caccagaggt cgggcggtcg
    14101 gcgtcagcgg cttcgcccca gggaatgctc agactggcga cgccggcgcc agggtaggtt
    14161 ttgtcctcgt gggccagcaa ggtcatggcg gccacggcaa actgggcgcg atattcggga
    14221 gccacccgtg gcaaccgggc cgtgaaggac tgccattcgg cttcgtaacg cccggcaatg
    14281 gcggcaaagc cctcggccag cgccgccgcg gcaacgttgg ctgccgtttc cgggcggtcg
    14341 gcaaaggcca gcgccaaagt cgtccggggc gcggacaact gtccaatctg cacgacgttg
    14401 ccatccacgg cgcgctgttc acgtccatcc agccgcccat cggcagccag atcggtccag
    14461 ccgtcgctga caccggcaaa gccgctcgac accacctcaa aggccggctg tgccgcgaaa
    14521 gccatggcaa tggtctggtt ggtcgtggca tcgcggtcgg aagccacaag cgtccggccg
    14581 cggtgctcgc ccgtgtcacc catgccgctg ttggccacgg ccgggtcaag cagggcaaag
    14641 acctcgtagt tgccgccgtc cagcgccgtc acttcgactt cgatgagcag cgcatcgcgg
    14701 tcggggtcgc aggcatagcg ttgcccgatg cgccaccgcc tgccgtcgct catggtctgg
    14761 gcaaaggaca gggcatcatc acgggtccgg cgcgtctccc gctccaaggc atcgcgggac
    14821 gcacacccga cgtacccgtt gccgacgatg acaaaatcca gcgcccgcag gttgggcata
    14881 tccaccgtcg ggtaatagac ctccgtcagg cccgttgcgc ccagggtgaa ccacacccgt
    14941 gatcgccgac tgacggccgt gcccacgccc agcttgccgc cggaagtcca ggtggacctg
    15001 acgccgggcc ggcccggagc gtctcccgct gcgtctcccg ctggcgcggg cggcagggaa
    15061 aacaaccccg gacagaccag cgccacggca agcacgatgc ttaccagttt catcatggtg
    15121 actccttgtg gaaaacacgc ttatcgaaca cgaaacaccc ggtagccaaa ggcttccacc
    15181 ggcacgcgca gggtttccct cacctgcatt tttctgtcgt tgacgggaaa tgaactgtgt
    15241 accgggttca ccgtgcacgg ccggttgggt gcgccgtcac aaatggaggc cgcaggtatc
    15301 ggcacttcgg cccggcttcc gctgccgttg acaacgacga gcagcctttc cttgccgtct
    15361 tcgcgcagaa aggcccactg ccggccttcc acaaccagat cgcgatggcg gccatgccgc
    15421 agcgcccggt ggcggcgacg gagcgccagc aactgctgcg tctcctccca cagtttctgt
    15481 tggtcgggcg tccgcccggc cggggtaaag gcattcgggg tatcgccgaa gccgccggga
    15541 aagtcgcgcc ggttgtcggg gtcttcgcca ccatccatcc cgatttcatc cccggcgtag
    15601 agctggggga tgccgcgcag cgtcatcagc agcgtcagag ccagtctgac gcgccgccag
    15661 tcgccgccac aggcgcgcat gacgcgcggt acgtcgtgat tgccgatgaa ggtgacgttc
    15721 aggtgggcgt tgccgtagag cgcatcctgc tgcaacaaac cggcaagacg ggacgccgga
    15781 gcatttccgg cggcaaaatc ccggatggca taaaagagcg gaaagtcaaa ctgcgaccgc
    15841 agcccggtgt caatgccgtc ccaaccggtt ctcccgccac gaaagaaggc aatgatgttt
    15901 ggatcgccat gccagatttc gccgacggcc gtgaagttcg gaaaggcgtc atccatggcg
    15961 cgctgccagt cgcgccagaa cggacggacg acataggggt aggtgtcgag ccgcatgccg
    16021 tcaagcccca ccttttccgc ccaccagagg gaattctgga tggcatagcg ttggtacttc
    16081 tcatctgcgc cgttgaggtc cggcaggata ccggcaaacc agccttcaag caccagcgcg
    16141 cgctcgtgcg gcgtggcatc cgggcgcgtc aacgccggga tgtcaaaatt gcaggtgagg
    16201 tgttgttccg gggttccgtt gaaccaggtc ggcgttggcg gacggcgcac ccaggggtgc
    16261 tgcggccccg tgtggttggg aatgacatcc tgaagcagct tcatgccgcg gcgccgcact
    16321 tcctgtgcca gcgtctggta ttgctccagc gttccgaagc gcgattcgac ggcgtaaaag
    16381 tccgtcgcgc cgtagccgtg ataatcctcg ccggcatcgg cgttgtcata aaccggcgtc
    16441 atccagatgg cggtgatgcc cagcgcctgg agatagtcaa gtttctcgat gacgccgcgc
    16501 aggtcgcccc cgtgataggc gcgtgggttg gcacggttgg ccggcggcat tccgggtggc
    16561 gcgtcgttgc tgcgatcgcc attggcaaag cggtcaatca tcagcagata gacgacatca
    16621 tccggtgtca ggccgcgaaa ggccgtcgtc cggggcaggg gcgaaaacac cgcccagggg
    16681 agcggccgcg cgccattggg cgtaagcaga ttgagttgga caggtccggg acgcgcctcc
    16741 ggggtgatgg tcacttcgca gaacgcatag cgcccgctgg agaccacctc gacccggccg
    16801 gctgtgatgc cgggagtgtc gctgacaagg cgcgcgccgg tcaggttttc acccgtgacg
    16861 agcagctcga tggtcgtcgg acgggtcacg gcaggccagt cgggcggctc gactttggtt
    16921 acaacctggg acaggcccac cacggtgagc cacaccagcc accagccacc gccgacggca
    16981 cagaacaacc agttgattcg tttcataagc ggggaaaggc agcgtgagcg gaacaggatt
    17041 ccgctcacgc ccggggtgcg tcaggtgaca ggctagaagg acaaccgcag gccaagctgt
    17101 accgaacggt tcgagcggtt gcgcaccgag aagatgcgcc cgaagtcgcc gcccagaaag
    17161 acgttcggga aaccaagctg gggtttgttg aacaggttga atgcctccgc ccggaactcc
    17221 agattgacgc gctccgtgat ggtaaagcgc cggaaaatgg agccatccac cgtggagata
    17281 cccggtgacc ggaggaaggc gttgcgtggg tattgttcgg acgggttggc ggagggtgca
    17341 aaggcatcgg tgttgaacca ccgcgcggca ctgcgccggc cggcattggg gtcctgcccc
    17401 ggcacaagcc gcgcccggcc gccatcgccg ccaaagaccg agaagggcgt tccgccctgc
    17461 agcgtcagga tggcgttgag ctggtagcca tagagcagcg cccggacaac ccggctgccg
    17521 gcttccctga aaaacggcag gtcgtagttg aaggcccagg tgaaccgatg ccgtacgtca
    17581 tagtcggcca gaccgggggc aagtccgccg ggatcggccg gcgtggagcg gccggcgccg
    17641 cccgttccgg gaaacggccc gggtgagttg ttggtggctt tcccgaaggt gtaggccgcc
    17701 aggtagctga ggcccttcca tgaccgctgg ttgaccttga tctggagcga gtcatagcgc
    17761 gattcaccca cgttggcgat ggtcgtcaac cgccgggtga tttcggcatc gccaaagccg
    17821 ccgacagttg tcacggcggt gacgttgtcg ccgcgcgtgc cgacgtatgc aatgtggaag
    17881 gccagaaagt cggtcaactg gtgctcgaag gtgacattga actgctgcac ccgcgtgttg
    17941 cgcgtgttgc gcggggtgaa gcgaatctgc gtgccgggcg gaaggttcgg ggaggcaggg
    18001 ttgatcgggt caggtggggg gatcggttgg cccaaccgga cgttcgagcc cgggccgtcg
    18061 aagcggaact gcgtcacgat gaacggcggg ttctgcgtca actggttggc aatgccgccg
    18121 cggtccagcg aatagaacag cccccagccg ccgcgcacca ccgtgcgccc attgccgaac
    18181 aggtcgaaag ccgcgccaat gcgcggggca aagttgttgc ggtcggtatc caccagcgaa
    18241 cgtgaattgc cgtcgcgccc ggccagcagg atgcgtccgc tggcgggatc aaagttggcc
    18301 atccggttgt tgagttcgta gtacggcgta aacagctcat aacgcaggcc ggcgttgagc
    18361 gtcagccgac ggttgatgcg ccagtcatcc tgcgcaaaaa agcccatctc atagctgcgc
    18421 gtcgtcgcgg ccgggatttc cgggttggcc gtggtggtaa aggctgtgcg cccgacgagc
    18481 atctgcgcca cctggtagcc ggtctgcccc aggcccggac tcgccggcgg cggcccgccg
    18541 gggcggaagg tcacgacctg gtcggagaaa aagtagaagc ccttgctgaa atccgcctgc
    18601 accgagcgga tgttgcgctg aatgatggaa gccccgaact tggccgaatg gttgccagta
    18661 acccaggtca cggcatcggt gaactgaatt gtccgctggt tgaggatgaa ctcgccaaag
    18721 tcgcccaggt attccagaaa gtccccgttg ccgccgccaa tgagcgaaat gccgttggcg
    18781 cgggtgatgc cgttgatgcc ggggatgcca agctgacggt tgaggtccgt cccgaagccg
    18841 agcggcagga actcgatgtt ctgcttgacg tagccaaacc gcagctcatt gacgacattg
    18901 ggcgtgaacg tgcgcgtgta gttgcccatc acgctgtggt tgaactgccg gttcgttcct
    18961 gaaccaaagc cggtctgggc gttgatgccc agccgccccg gatcgaactg cgggtcgtcg
    19021 gcaatgctga accgcacaaa gacggtatcc cgctccgtga accggtggtc cagccggagg
    19081 tcgccgccct tgaagttctg ccgctggagc tggcggttga agaagttgaa gcgcgcccgg
    19141 tcaggcaggt cgggaagcgg aaagaagttc agataccgga cggcagccgg gtcgagccgg
    19201 ttctggggaa tgatgttgcc cggaaacggc agtccggtca gcgggtcgaa aatctgcacc
    19261 gccgcgccca gaccggtgaa gttgggattg agcagttcgc tgaaatcgcc ctgccgcatg
    19321 cgcgccgtcg gcacggtgaa ggtgcgtcct tcctcacgcg gcagccgctg ccgcagttgc
    19381 tggtagtcgg caaagaaaaa cgtcttttca cggacgatgg ggccgccgaa ggtgccgcca
    19441 aactgattcc gtatgaacac cggtttgggc ggcacaaagc cgacgagatc agtggcgcgg
    19501 gcatccatgg ccgagttgcg gaaaaactca aaagccgagc cgtgaaaatc attcgagccg
    19561 gagcgaatcg tggcgctgac aatagccccg ccaccacgcc cgaactcggc cggggccaca
    19621 ctcgtgatga cccgaaactc ctcgatagct tcaatgggcg ggaaaaacac gatgctgttg
    19681 acaatggact cattgttgtc aatcccgtcg agggtgaagt tgttgttctg ctcccgcaga
    19741 ccgttgacgg agagcgccgc cgagccggtg tcaccctggc ggaaggtttc ggcgttgccg
    19801 ccggacccat cggcgttgct gcccggtgtg ccgcgcgtca cgcccggcgt cagcgtggcc
    19861 aactgggtga agttccgccc gttgatgggc aggtcaacga tctgccggcc ggtgatggtc
    19921 tgcccgacgg acgaactcgc ggtttccacc agcggcgcgc cagccgtgac ctccacgaca
    19981 tccgtgatgt tgcccggctc cagctcggca ttcaggctga gcacctgatt gacgcgcaaa
    20041 acgacttccg ggcgagcaag tttcttgaag ttgggcgctg aaaattcgat gaggtaggtt
    20101 ccggccttga gtaccggaaa cacatagacg ccatcggcgt tggttgttgt ttcaagtttg
    20161 gcattcgttg cggtttcggt ggcggtgacg gtcgcgccgg caatgacgct gccgctcgtg
    20221 tcggtgatga caccggtcag ccgcgccgta tcactctggg ccagcgccgg ccagacgaaa
    20281 ccaaacagaa cgcccaaaag tatgccgcac gaacggagcc agcaatgtgt tcgccgccgt
    20341 ttcaaaccgg tttctgcggc tgacacacac caccccatgc gcgcggggtg agcgtaagac
    20401 atagggggat tcctcctgag aaatgatgct ctcatcgccg ccgacagggg gtggccaagt
    20461 cgggccaaat tgggctgaag catctgcgca cgttgtacgt ccgctcatca gatctggatg
    20521 caggcgcgct tccgggcgca catctcctga ttacccttgg cggcagggcc cactccgttg
    20581 gggggggcgg aatgagcgcg tcatcaatgt tgacgctgcg ttacaagcgt gttagagcgt
    20641 gcggaaactt acgaagtctg tctcacggtg tcaaccgccc cccggccgac aagtgaaaaa
    20701 aaatctggtt ccgggttcct gggagcgatg gtgtgcctgg tgcccccgtt ggtgcccttc
    20761 ggcaacgtca cccggcaatg gcaaccgccg tgtttgtacc cggagaacaa aatgaccatg
    20821 gcctcgtctc cgtcttctgc tctgtcgcgt cgtcgcccga tgagcgacat tttcaccatg
    20881 aattttggct ttctgggcat ccagttcggc tggggcctgc agatggccaa catgagtgcc
    20941 atctacgaaa aactcggtgc acagccggat gagattcccc tgctctggct ggccgcgccg
    21001 atgacgggcc tcatcgtcca gcccattgtc ggcgcgctga gtgaccggac gtggacgcgc
    21061 ctgggccgtc gccggcccta ctttctgacc ggggccattc tggccagtct ggcgctgttt
    21121 gccatgccac actcgccagc gctgtgggtt gcggcaacgc tgctctgggt tctcgacagc
    21181 agcatcaacg tcagcatgga gccgttccgg gcctttgtcg ctgaccggct cgatgacgaa
    21241 cagcgtccgc tgggcttcgt catgcagagc tttttcatcg gcgttggcgc aacactggcg
    21301 aatgttcttc cctacatcct gcgcgaatgg ctggacatca ccgggcgcgc cgccaatggc
    21361 gtgccactgg caacgctcta ctccttccag cttggtgcgg cggcgtttct gggcgcggta
    21421 cttgtcacgg tactgacgac gcccgaagac ccgccctctg acctggaggc gttccgccgg
    21481 gcgaaggcgc aggccggtgt ctttgactgg gttggcgaca ttggaaatgc cctgacggcc
    21541 atgccatcgg tgatgaagcg gctggctgtg gtgcaggtgt tgacctggct ggggctgttc
    21601 tgcatgtggc tgttttttgg cccggccatc gcgcgtcata tcttcggagc ggccgatccg
    21661 gcggctccag cctacgacga aggcatcaac tggggcggca tctgctttgc cacgtattcg
    21721 gtcgtctgct tcgtcgtggc ctttgccctg cccaagctgg cagcgcgtca cggttgtgca
    21781 accgtccatg ccatcgccct gacctgtggc gggctgggac tgctctcaac gggactcatc
    21841 gccaaccgct actggctgct ggttgccatg gttggcgtcg gcattgcctg ggcctcgatt
    21901 ctctcgatgc cctacgccat tctggcgcgc gctctgcccg gcaaccggat gggggttttt
    21961 atgggcatct tcaacttctt
//
