LOCUS       NZ_CP072647            21564 bp    DNA     circular CON 02-DEC-2024
DEFINITION  Chloracidobacterium sp. MS 40/45 chromosome 2, complete sequence.
ACCESSION   NZ_CP072647
VERSION     NZ_CP072647.1
KEYWORDS    RefSeq.
SOURCE      Chloracidobacterium sp. MS 40/45
  ORGANISM  Chloracidobacterium sp. MS 40/45
            Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia;
            Terriglobales; Acidobacteriaceae; Chloracidobacterium;
            Chloracidobacterium aggregatum.
REFERENCE   1  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Genomic and phenotypic characterization of Chloracidobacterium
            isolates provides evidence for multiple species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 994789)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2021) Department of Biological Sciences, Tokyo
            Metropolitan University, 1-1, Minami-Osawa, Hachioji, Tokyo 1920397,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu 1.8 assembler v. 1.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018304805.1-RS_2024_12_02
            Annotation Date                   :: 12/02/2024 00:41:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,029
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,951
            CDSs (with protein)               :: 2,951
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 7 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 164256
            Orig. end                         :: 185820
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072647.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21564
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21564
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21564
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11564](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11564)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            complement(501..1250)
                     /locus_tag="J8C02_RS11820"
                     /old_locus_tag="J8C02_11820"
     CDS             complement(501..1250)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_11820"
                     /product="hypothetical protein"
                     /protein_id="WP_211427487.1"
                     /transl_table=11
                     /translation="MLRRTSLLSCGLLVCVLALALGSARAADEPTLESVVAQIVKAQGG
                     EKLKTIKSIKTSGKLVFGGGQAEGPLVGFVARPGKIRQEISLSGARLVQAYDGTTAWQI
                     NPFAGSSKPEKMSEDEAGDLMDSADMDGPFVDSAKKGYKLELAADEELDGTPVHVVKVT
                     NKRGKVETYYVDAASGLILKVRGKEKIQGNEVEVETLLSNYKEVNGIMTAHAVDRLIGG
                     QPFIQIVFDRVEHNVELEDSLFRMPEE"
     gene            complement(1368..1838)
                     /locus_tag="J8C02_RS11825"
                     /old_locus_tag="J8C02_11825"
     CDS             complement(1368..1838)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004274480.1"
                     /locus_tag="J8C02_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11825"
                     /product="VOC family protein"
                     /protein_id="WP_211427488.1"
                     /transl_table=11
                     /translation="MQTTLYPFHLAFPVTDLAATRRFYVELLGCRVGRESDDWIDFDFW
                     GHQITAHRIAGRAPVAGHNPVDGKSIPVPHFGVVLDWETFHTLAERLTRAGVTFVVPPY
                     IRFAGQVGEQATMFFCDPAGNHLEFKAFRHAAELFAHPGAAGGQRTGGETIQ"
     gene            complement(1877..2875)
                     /locus_tag="J8C02_RS11830"
                     /old_locus_tag="J8C02_11830"
     CDS             complement(1877..2875)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006784 - heme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014101381.1"
                     /locus_tag="J8C02_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11830"
                     /product="COX15/CtaA family protein"
                     /protein_id="WP_211427489.1"
                     /transl_table=11
                     /translation="MTGEREGLTAGAPAEDRLRRFAWGVVGWNVLVIVWGAYVRASKSG
                     DGCGSHWPLCNGEVVPPAGQFATFVEFMHRATSGIALLGVVGLVVWSFRRFARGHHVRR
                     AAGWSLAFILIEALIGALLVKLELVADNRSVARAVYMSVHLVNTFLLLGALTLTAYWIS
                     GFPPARLSGHERTVRHLLASFVAALVVGVTGAIAALGDTLFPATSLAQGIAEEFSGLAH
                     FTVKLRWLHPVAAVLASAVIVMAAARLRTGPATARMSAVVIAIVGAQFVLGIINVWLLA
                     PIWMQLIHLFFADALWVALVLLAAAALGQDAETVTPATLGARASRPQMVMQ"
     gene            complement(2872..3702)
                     /locus_tag="J8C02_RS11835"
                     /old_locus_tag="J8C02_11835"
     CDS             complement(2872..3702)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF014898.5"
                     /locus_tag="J8C02_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11835"
                     /product="site-specific integrase"
                     /protein_id="WP_211427490.1"
                     /transl_table=11
                     /translation="MTGPGLAAGRLDACRWAFLTRLGSETTRRVYGVALVQFDAWLREQ
                     GKGWLDATPEDVRAFCQFLLARVSPPTVGVRLTALRKFYTELVAHRLVGHNPARIVGPS
                     TRGRRRVAACDAPLLAALLALPDTRTLVGLRDACVLRLLGEPGLRVSEICLLRQQDVVR
                     YPDVETGLGLHVGQGTRWVRTVGLSPAVKAALDAYLRRDLPLRRLARGFGPEAALIQGT
                     AANRPVGGPSLTPRFIFKLVRRYGMLLDCPTLNPQMVRRAARAKAPEEGSVTNV"
     gene            complement(3699..4097)
                     /locus_tag="J8C02_RS11840"
                     /old_locus_tag="J8C02_11840"
     CDS             complement(3699..4097)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_11840"
                     /product="hypothetical protein"
                     /protein_id="WP_211427491.1"
                     /transl_table=11
                     /translation="MKSLPMPLISIVNGAALIGVSVIGYVLKDPANSGKTALIPGAFGV
                     LLVLCGGLALRESLRKHAMHAASAVALLGTVGGLVPIVMSLMNGTFGARPLALVVQIGM
                     LVICGETLALCIISFVQARRRRAQEAAG"
     gene            complement(4232..8422)
                     /locus_tag="J8C02_RS11845"
                     /old_locus_tag="J8C02_11845"
     CDS             complement(4232..8422)
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013524.5"
                     /locus_tag="J8C02_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11845"
                     /product="C25 family cysteine peptidase"
                     /protein_id="WP_211427492.1"
                     /transl_table=11
                     /translation="MKPQRITTWFRSAVRPLYVLILIGLLVAGIPPALRKPEVRAAKTP
                     LNAQMITTRDSDAPLANGDFVGCSTSPGLNSYYSVFIEVPSGTSRLTIDIYDADYGSTG
                     GPAGVNRFDNRVGAITTNYSLFDPSGTSISLNTILSGTGLNFTEGDNTAVGTNGPDTRA
                     ANDQWKNFYTVASPAAGHWELRIIQPGGGNSGVNPFGVAAHTLDPGANRDQNLGGPTTG
                     RGLNMYFDPGIHLGPQNTERQPPITWNYYPYITSGCTCRANDFDWDAPGGTGTIAFTSR
                     TGSQTFNTTTVSGATVWGSFEVGPWTTSVSAVDYGIWSNNITINGGGANHITYYIGNHS
                     ALVPTTSGDNITLANWRQGDKFRVYFPGDAGATTAPLKPYMTQRLIHIGNPTNGPNPPC
                     NGQTTFYRVRVDIVNPTDHDIVLDGTTIGTRTRRVVANIPTVTGVFYANESTYGGAQAT
                     QGTFTQPANDATSGSITWTPGTIAANSAASLFYVIRVSPTGSSPCVMNVTGTPGGTPEG
                     TTAVWRDETGNTTQERATYTFGPLCELAVNRNGTCTGCTGSSPPPTPTKVDLTGFEATR
                     YATGDVLVQWATGYESAHLGFHVWREREGRRERLTPELVAGSALLTSDALTAGQRYTWR
                     DETVRLARGGASYWLEAYDLDGSRQWYGPVVLRQTREAVPLALLKNSPLLGHGTSRLGR
                     QIEDDAAPAVAEPTGRKAASRHKAGLENQGDLEVQQWLAAQPAVKLRVTRTGWQRVTFG
                     ALVAAGLSPTADMERLHLYVRGRQVPLRVTGEGIEFYGVAEDTPESGEQVYWLIEGRTP
                     GERVGPGAGAPMLRPTFQHFRSRVTRADKSIYFAALLNGDEDNFFGSVVTNSPVAQDIV
                     VRDPAAASGEPAQVSVELQGVSLGAHTVNVWWNGQPLGAVTYTGRDTGQATWTVPAGQV
                     LNGVNTVTLQAPEAGDVNLVKTLTVEYARQLHAADDRLLVHVPRAGGRPVLHVGGFTAP
                     VSAFDITEPEAPVQLPVRMLGATATLAAQPGRDILLTTTAAMWSPQVEANTPSAWHRAD
                     VAADFVILTHGAFRPAAERLARVRQAEGLRTVVVDIADVYDEWGYGAPSTAAVRAFLET
                     AATRWARPARYALLVGNATFDPRDYLGFGGNFIPTKLLAVGTLETAVDDWFGDFGGTGL
                     AQLAMGRLPVRTPAEAEIVIGKTLTYEQAGAADWKQRVVVVADDPDAGGDFDQAAADII
                     GLAPDPAQVTPIRLSVLGAAGARAAVLASFSSGAGLVNYVGHGSTQNWAAENLLTSTDA
                     ATLTNTGQPAIVVGMTCLNGFHHDLYTTSLGKALVLAPGGAVATWSSSSLTVSAEQHGA
                     NVALLDAMYGLEPAMRLGDAIRRAKLGTGSVEVRRSWTLLGDPTLRVRETPRR"
     gene            complement(8419..8856)
                     /locus_tag="J8C02_RS11850"
                     /old_locus_tag="J8C02_11850"
     CDS             complement(8419..8856)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_11850"
                     /product="S24/S26 family peptidase"
                     /protein_id="WP_211427493.1"
                     /transl_table=11
                     /translation="MTNAGWTTLVRSLLAQGLPVRFTAPGRSMAPTIADGETITVRPLS
                     ADDRPECGEVVLAQVDDRLIAHRIVEMHPAADGTWDDTWFVLRGDAQGQATDVVPRRAI
                     LGCVVLPPRSCRARLAGAVWRLRQRCARWKPFLKPVLEKMP"
     gene            complement(8853..9719)
                     /locus_tag="J8C02_RS11855"
                     /old_locus_tag="J8C02_11855"
     CDS             complement(8853..9719)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_11855"
                     /product="hypothetical protein"
                     /protein_id="WP_211427494.1"
                     /transl_table=11
                     /translation="MIGGLRLAVDARGLDLPMHISGPTARFVVPWEDAPADAAIRVGWL
                     DEAVPLPEPMELVFASGGMWTLYRAAGGYRYDIASPVFGPEPYRIAWFDPTYQTGHVWY
                     RRLPAVIAAMQSPLEYPVDELLVTNLLARGRGVELHACAVVDTDGRGWLFVGQSGDGKT
                     TTARLWTRAGATVLSDDRVIVRQCDGQWLMFGTPWHGEGEFAAPAAAPLNGLFILCKGA
                     EDAARPLTPGLAAARLFARAFPPFYDAAALDFTVGFLERLVTAVPCYELVFRPTPAVVD
                     YVRRMQP"
     misc_feature    9776..9787
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(9895..9911)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            complement(10001..11254)
                     /locus_tag="J8C02_RS11860"
                     /old_locus_tag="J8C02_11860"
     CDS             complement(10001..11254)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="J8C02_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11860"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_211427495.1"
                     /sec_met_domain="PF04055 (E-value: 2.4e-17, bitscore: 59.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1e-07, bitscore: 27.8,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESVSYAELSRRLHGRLLAGRIPLEATFEVSRRCPLVCQHCYNNL
                     PMNDHAARRRELSLDEYRRIFDEIAEAGTLWVLFTGGEIFARRDFLDIYTEARRRGFII
                     TLFTNGTLLTPRIADYLAEWRPFAIEITLYGHTRETYERLTRVPGSYDRCHQGIRLLLE
                     RRLPLKLKTVGTTITRDEIFAMRDFAESLGVPFKFDSMINPRVDCSQSPLEVRLTPEEV
                     VELDLRDPRRMTAWRDLNDRYRTAAVAPYVSNTVYDCGGGVGSFAVNPYGEMSICVLSQ
                     VDTYDLRQGSFREGWEQFLRRVRLQTRTRPAKCTSCEIRLMCTSCAAVNELENGDKEAA
                     VDFFCRTNHLRAYLLGLDLKPNPLCEYRPGSERYEDIQASVAALRARAQELGVELTFQS
                     RRALPVLQARPVVAEPTP"
     gene            complement(11265..11564)
                     /locus_tag="J8C02_RS11865"
                     /old_locus_tag="J8C02_11865"
     CDS             complement(11265..11564)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="J8C02_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11865"
                     /product="PqqD family protein"
                     /protein_id="WP_211423336.1"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 59.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.7e-07, bitscore:
                     25.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.9e-10,
                     bitscore: 35.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLVKKLPCVTRRIADETLLIPIRGQAADLDAIYVLNDTAALLW
                     SQLDTTGDVAALGAVLCEAFEVSPEQAAQDVAEFLAALEESGIIEVPCAASSAA"
     aSDomain        complement(11292..11462)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J8C02_RS11865_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.00E-11"
                     /identifier="RREFam002.1"
                     /label="J8C02_RS11865"
                     /locus_tag="J8C02_RS11865"
                     /protein_end="91"
                     /protein_start="34"
                     /score="35.7"
                     /tool="antismash"
                     /translation="YVLNDTAALLWSQLDTTGDVAALGAVLCEAFEVSPEQAAQDVAEF
                     LAALEESGIIEV"
     aSDomain        complement(11295..11465)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J8C02_RS11865_PqqD_RRE.1"
                     /evalue="9.90E-09"
                     /identifier="RREFam006.1"
                     /label="J8C02_RS11865"
                     /locus_tag="J8C02_RS11865"
                     /protein_end="90"
                     /protein_start="33"
                     /score="25.8"
                     /tool="antismash"
                     /translation="IYVLNDTAALLWSQLDTTGDVAALGAVLCEAFEVSPEQAAQDVAE
                     FLAALEESGIIE"
     misc_feature    11538..11554
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    11542..11551
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    11719..11734
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            11932..15861
                     /locus_tag="J8C02_RS11870"
                     /old_locus_tag="J8C02_11870"
     CDS             11932..15861
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013507.5"
                     /locus_tag="J8C02_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11870"
                     /product="hypothetical protein"
                     /protein_id="WP_211427496.1"
                     /transl_table=11
                     /translation="MSSRLLTRLGLVLMLCLHPLLLSLPPTLASGGTPRPLRPSQPPAH
                     TRTAPTTLALPGAAQWRTLTLDERVRYRRAIEQVYWKRRRWEATTPKPAFDRLFSQPQL
                     RALVADELCQQHALDLLWHHAPTPAELHAEVSRMMRHSKQPEVLQELFAALDNDSIAIA
                     ECLARPVLVRQRLQADYARDRRFHGRLEAQVRQALEIAPAVETLSRLGAVCTEVEFIRR
                     DRPEAFAVADLRRLPVSGADWEHEMARLAERFGSHPAKLAPGMVTPLCEDDERFFIQQL
                     QAIESDRVRLVTAEWRKVDFDTWWAQVRANYSPVIPTVSGSFPELRAPGAVESGFPEAI
                     AGNDNRWAQDAGDGVPSARFRHTAVWTGVEMIVWGGFRGTFSGGSPLNTGGRYNPITDT
                     WTPTRVAPSAIGATDAAPAPRVNHTAVWTGTRMIVWGGVSGTPVNSGALYDPVENKWTA
                     TRTDPSSSTANDGAPAARFSHVAVWLAQAGRMVVWGGNLNFVGSVPIPTNTGGVYNPET
                     NAWSATATTGAPQARTDHVAVSTGTAMIVFGGVNADGGRLNSGGIYTPSNNTWTATSTT
                     NAPGLFTPSAVWTGTELLVWGSVAGAPAPTVAGARYNPANNTWTAIATAGAPTPRVNQS
                     TVWTGTEMIVWGGAALDVRFNDGGRYNPATNTWTPVTTVGAPSGRENHTAIWTDAYAEP
                     NQNATKYMIVWGGQGGDATGGRYDPLTNTWLPTATTPVPIAREGHTAVNTGVEMIIWGG
                     ASAGVRTLTGGRYNLATAQWLPTSTQGAPGAAINLPPVGHTAVWTGSEMIIWGGQTNAG
                     GRYNPVTNTWTPTSLTNAPSAREEHTAVWTGSEMIVWGGRFTNPSNNETNYFDNGGRYN
                     PATDTWAATAADGRPGPRSRHTAVWTGSEMIVWGGVTFADNRFSELRTGGRYNPTTNTW
                     TPTRTDPTSSGGTDGAPDARFDHTAIWTGDRMIVWGGATTAARAFNSGALYNPAADTWA
                     ATSANGVPSARSGHTAVWTGREMIVWGDAGATGGRYNPTFDFWRPVETEGAPDLTASHT
                     AIWDATRRQMVVWGGRGSGGVSNALGAYGARGEQGDTVGVFRRGQFFLRNSNTSGNADL
                     AFTFGAEGDVPLAGDWNGDGITTVGVFRNGTFFLRNSNDSGVADIAFAYGGAEDIPLAG
                     DWDGNGTTTIGVYRPATRTFFLRNTNTAGNPDIVVVYGEEGDRPLVGDWDGNGTTTVGV
                     VRGNTFLLRNANTGGDADLVFNFGNPDDKVVVGDFDGDGVDTVGVYRGLTFFLRNTNLP
                     GTADFLLVYGADGDVPLVGNWDGQL"
     gene            complement(15911..17554)
                     /locus_tag="J8C02_RS11875"
                     /old_locus_tag="J8C02_11875"
     CDS             complement(15911..17554)
                     /EC_number="6.3.5.1"
                     /GO_function="GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100793.1"
                     /locus_tag="J8C02_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11875"
                     /product="NAD+ synthase"
                     /protein_id="WP_211423338.1"
                     /transl_table=11
                     /translation="MKIALAQINTMVGAFVANAAKVRQYAMRAALQGARLVVFPELTIP
                     GYPPLDLLDRPAFIARNLAALDDLVRFSATVDTALLVGFVAENPDDFGKPLYNAVALLE
                     GGELRAIRYKTLLPTYDVFDEARHFEPSERREIIRWNGYRLGVCVCEDAWNSREFWDTH
                     LYDIDPVRELAEQGAQVIINVSASPFHRGKGALRQAMLAHHASTLKVPVVLVNQVGGND
                     SLVFDGRSLVLDAQGELVLEAHAFQEDLRIVDLADLPAPITPRITDEVADIHDALVLGI
                     RDYLGKCGFRQAVVGLSGGIDSAVTAALAVQALGPENVTGVAMPSKYSSDHSLEDAAEL
                     ARNLGIGFHVVPIEPAVSAMTQMLTPAFGFPPHGVTEENLQARLRGVTLMAFSNQSGAL
                     VLTTGNKSELAVGYCTLYGDMCGGLAAISDVPKTDVYRLAAYINRHRVVIPTRTITKPP
                     SAELRPDQTDQDTLPPYDILDAILERYIERYQSLDEIVAEGFDRATVEYVARLINRNEY
                     KRQQAAPGIKVTPKAFGRGRRVPIAAVIES"
     misc_feature    17612..17624
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.89"
                     /tool="antismash"
     misc_feature    complement(17723..17732)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     gene            17839..18231
                     /locus_tag="J8C02_RS11880"
                     /old_locus_tag="J8C02_11880"
     CDS             17839..18231
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012442.5"
                     /locus_tag="J8C02_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11880"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_082670891.1"
                     /transl_table=11
                     /translation="MAAKAPKSTATKATTKAKATAPKEEAPAKKAPAKKAAAKPMTKTE
                     IVNHFAEKFGFPKQKVREFFDEQARLAAAQAKVGFTIPGVGKLVVREYKAREGRNPRTG
                     EKIKIKARKRLKFVISAAAKKAAGFE"
ORIGIN
        1 ggctctggtc aatggtcagc gcgccgatgg actgggggtg tttgtcaaag accgggcgga
       61 aggtcagacc gccatcggcc gacttccaca cgccgccgct ggccgcgccg gcatagatga
      121 tttttgggtt ggtgttgacg acatcgaggg cggcaatccg gccgctcatc gttgccgggc
      181 cgatggcccg tgcggtgaaa gctccgagca tcgaggcatc cagcgccacc ggagcggcgg
      241 ccggggccgg ggccggagcc gccggcgtcg ggttggaagg ttgctgggcc ggggcgctgg
      301 ccgcaaacag gcagcacagg gcgagcgccg ccatgaacag tggcttgagg gtgtccatag
      361 gctgtgggag aaggctttgg gagaacagtg gtgttggcgt tgaactggaa gtgaaagccg
      421 cccggaagga cgccagtcag cagagcgcat tggcgtaacg accgggccgg ccggatgacc
      481 ggcccgatca accggtcagg ttattcttcg ggcatcctga acagactgtc ctcaagctcg
      541 acgttgtgtt ccacccgatc aaacacaatc tggatgaacg gttgcccgcc gatgagccgg
      601 tcaacagcat gggccgtcat gatcccgttg acttccttgt agttggaaag cagcgtctcg
      661 acttcaacct cgttgccctg aattttttcc ttgccccgga ccttgagaat gagaccgctc
      721 gcggcatcca cgtagtaggt ttcgaccttg ccgcgcttgt tggtcacttt gacgacgtgg
      781 accggcgtgc catcgagttc ctcatctgcc gccagctcca gcttgtagcc cttcttggcc
      841 gaatccacga aggggccgtc catgtcggcg gaatccatca aatcgccggc ctcatcctca
      901 gacatttttt cgggtttgga agaaccggca aagggattga tttgccaggc cgttgtgccg
      961 tcgtaggcct gcacgagcct ggctccactc aaactgattt cctggcgtat tttaccggga
     1021 cgcgccacga aaccgaccag cggcccctcg gcctgcccac cgccgaagac cagcttgccg
     1081 ctcgtcttga tggatttgat ggttttcagt ttttctccgc cttgcgcctt gacaatctgg
     1141 gcaacgacgg actcaagcgt cggttcatcg gcagcccggg cgctgcccaa agccagtgcc
     1201 agaacacata ccaaaagccc acaggacaac agcgaggtgc gacgcagcat gcgaaagctc
     1261 ctttgaagga agaatggttg aaagtcaggg tgtgtgcgat catggcgtgg taacgcccac
     1321 agcagccgta aagttctcag gaagttttcc cggacaacac acggcagtta ttggatggtt
     1381 tcacccccgg tgcgctgccc cccggcagcc cccggatgcg cgaacagttc ggcggcatgg
     1441 cggaaggctt tgaattccaa gtggttgccc gccgggtcac agaaaaacat cgttgcctgc
     1501 tcgccgacct gcccggcaaa gcggatgtac ggcggaacga caaacgtcac acccgcccgg
     1561 gtgagtcgtt ccgccagcgt gtgaaaggtc tcccagtcaa gcaccacacc aaagtgcggc
     1621 accgggatgg atttgccgtc caccggattg tggcccgcca ccggtgcgcg gccggcgatg
     1681 cggtgtgccg tgatttggtg tccccagaag tcaaagtcaa tccagtcgtc gctttcacgt
     1741 cccacccgac agcccagcag ctcgacgtaa aagcgccggg tagccgccag gtccgtgacc
     1801 ggaaaagcca gatgaaaggg atacaatgtc gtttgcatgg cgtgccttcc tgctgggagc
     1861 gggggcctcc agcccgctat tgcatgacca tctgcgggcg ggacgcccgc gctcccaggg
     1921 tagcgggtgt caccgtctcg gcatcctgac caagcgccgc cgcagccagc agcaccaacg
     1981 ccacccacag ggcatcggca aaaaacaggt gaatgagctg catccagatg ggcgccaaca
     2041 gccagacgtt gataatcccc agtacgaatt gcgcgcccac gatggcgatg acgaccgcag
     2101 acatccgcgc cgtggcgggg cccgtgcgca gccgggcggc cgccatgacg atgacggcgc
     2161 tcgccagtac ggccgccacc gggtgcagcc accggagttt gaccgtgaag tgcgccagtc
     2221 ccgaaaactc ctcggcaatc ccctgcgcca gtgaagtggc cggaaacagc gtgtcgccca
     2281 gcgccgcaat cgcgcccgtg acgccgacca cgagcgccgc cacgaaggac gccaacagat
     2341 ggcggacggt cctttcgtgg ccggacaacc gcgctggcgg aaaaccgctg atccagtagg
     2401 ccgtcagggt cagtgcgcca agcagcagaa acgtgttcac cagatgaacc gacatataga
     2461 ccgcccgcgc caccgagcgg ttgtccgcca caagctccag tttgacgagc aatgcgccaa
     2521 tgagcgcctc gatgagaatg aatgccagtg accagccggc cgcccggcgg acgtgatgcc
     2581 cacgcgcaaa gcgccgaaac gaccagacca ccagccctac aacgcccagc agggcaatgc
     2641 cgctggtggc ccggtgcata aactccacaa aggtggcgaa ctgtcccgcc ggcggcacga
     2701 cctcgccgtt gcagagcggc cagtggctcc cgcagccgtc accggacttt gacgcccgga
     2761 cgtaagctcc ccagacgatc accagcacat tccacccgac cacgccccag gcaaaacggc
     2821 gcagccggtc ttcggccggc gctccggcgg tcaatccttc acgttcaccc gtcatacgtt
     2881 tgtcactgaa ccttcttccg gtgctttggc acgcgcggcc cggcgtacca tctgggggtt
     2941 gagcgtgggg cagtcgagca gcatgccgta ccgccgcacg agcttgaaga tgaaacgtgg
     3001 cgtcagggaa ggccccccga cgggacggtt ggccgccgtg ccctggatca gggccgcctc
     3061 cggcccaaag cccctggcca accgacgcaa cggcaggtca cgccgcagat aggcatccag
     3121 cgccgccttg accgccggcg acagccccac ggtccgcacc cagcgggtcc cctgccccac
     3181 gtgaagtccc aggccggttt ccacatcagg atagcgcacc acatcctgct gccggagcag
     3241 acagatttcg gacacgcgca agcccggttc cccaagcagc cgcagcacac aggcatcgcg
     3301 cagaccaacc agcgtacggg tgtccggcag cgccagaagc gccgccagca acggcgcatc
     3361 gcaggccgcc acccgtcggc gaccgcgcgt tgacggcccc acaatccggg ccgggttatg
     3421 ccccaccaga cggtgcgcca ccagttccgt gtagaacttc cgcagcgccg tcagccggac
     3481 gccgaccgtc ggcggggaca cccgcgccag cagaaactga cagaaggcac ggacatcttc
     3541 cggtgtggca tccagccagc ccttgccctg ctcccggagc caggcatcga actgcaccag
     3601 cgccacccca tacacccgcc gggtcgtttc tgaccccaga cgggtgagaa atgcccaccg
     3661 gcaggcatcc agcctgccgg ccgccagtcc ggggccggtc atccggcggc ttcctgcgcg
     3721 cgccgccgcc gcgcctgcac gaacgaaatg atgcacaggg caagtgtttc accgcagatc
     3781 accagcatgc cgatttgcac gaccagcgcc agcgggcgcg cgccaaacgt gccattcatc
     3841 aaactcatga cgatgggaac gagaccgcca accgtaccga gcagggccac ggccgaagcc
     3901 gcgtgcatgg cgtgtttgcg gagcgattcg cgcagcgcca gcccgccaca cagcacaagc
     3961 agcacgccaa acgcgcccgg tatcagcgcc gttttgccac tgttggccgg gtccttgagc
     4021 acgtaaccaa tcacactcac ccctatcagg gcagcgccgt tgacaatcga aatcaatggc
     4081 atcggtaggg acttcatgtt ttctcaccct tcacagaggc cctgcatcca gggcgcaaga
     4141 tgcgcgccgt ccaaaaaatg agcgccgcac ccatcgtacg gcgctcatga gcctcaatca
     4201 agccacgcca gtcaccggcg cagccaccat gctaccgccg gggcgtctcc cgcacgcgca
     4261 gcgtcgggtc gcccaacagc gtccacgacc gccgcacctc cacactgccc gtccccagct
     4321 tcgcgcgccg gatggcatcc cccagccgca tcgccggctc cagcccgtac atggcatcca
     4381 gcagcgccac gttcgccccg tgctgctccg cgctgaccgt cagcgacgac gaagaccacg
     4441 tcgccaccgc cccacccggc gccagcacca gtgccttgcc gaggctggtc gtgtacagat
     4501 cgtggtgaaa accgttcagg caggtcatcc cgacgacaat cgccggctgc cccgtgttgg
     4561 tcagcgtcgc cgcatcggtg ctggtcagaa ggttctcggc cgcccagttc tgcgtcgagc
     4621 cgtgcccgac gtagttgacc agcccggctc cactgctgaa gctcgccagc accgccgccc
     4681 gcgccccggc cgcgcccagc acactcagcc ggatgggcgt cacctgcgcc ggatcgggcg
     4741 ccagaccgat gatgtccgct gccgcctggt caaaatcgcc gccggcgtca ggatcgtccg
     4801 ccacgaccac cacccgctgt ttccagtccg ccgcgccggc ctgctcatac gtcagcgtct
     4861 tcccgatgac gatttccgcc tcggccggcg tcctgaccgg cagccgcccc atcgcaagct
     4921 gcgccagccc cgtcccgcca aagtcgccga accagtcgtc caccgccgtt tccagcgttc
     4981 caacggccag cagcttcgtc gggatgaagt tcccgccgaa gcccagataa tcgcgcgggt
     5041 caaacgtggc attcccgacc agcagcgcat accgcgccgg ccgcgcccac cgcgtggcgg
     5101 ccgtctccag aaaagcccgc accgcagccg tggaaggcgc accatagccc cactcgtcat
     5161 agacatcggc gatgtccacc accaccgtcc gcagcccttc cgcctgccgc acccgcgcca
     5221 gccgctcggc cgccggacga aatgccccgt gggtcaggat gacgaaatcc gcagccacat
     5281 ccgcacgatg ccacgccgaa ggtgtgttgg cttcaacctg cggcgaccac atcgccgccg
     5341 ttgtcgtcag caggatgtcc cgccccggct gcgccgccag cgttgccgtc gcccccagca
     5401 tccgcaccgg aagctgcacc ggcgcttccg gctccgtgat gtcaaaggcg ctcaccggcg
     5461 ccgtaaagcc cccaacgtgc agcaccggcc gcccgccggc gcgcggcacg tgaaccagca
     5521 gccgatcatc cgccgcatga agctgccgcg catactccac ggtcagcgtc ttgaccaggt
     5581 tgacatcccc ggcttccggc gcctgaagcg tcaccgtatt gaccccgttc agcacctgcc
     5641 cggccggcac cgtccacgtc gcctgcccgg tgtcacgccc ggtgtacgtc accgccccaa
     5701 gcggctgacc attccaccag acattcaccg tgtgcgcccc aagcgacacc ccctgcagct
     5761 cgacgctcac ctgcgccggc tcgccgctcg ccgccgccgg gtcgcgcacc acgatgtcct
     5821 gcgccaccgg gctgttcgtc accacactcc cgaagaagtt gtcctcatcg ccgttgagca
     5881 gcgccgcaaa gtagatgctc ttgtccgccc gcgtcacccg cgagcggaag tgctgaaacg
     5941 tcgggcgcag catcggcgcg ccagcgcccg gccccacccg ctcgcccggt gtgcgtccct
     6001 cgatgagcca gtacacctgc tcgccgcttt ccggcgtgtc ctccgccacg ccgtaaaact
     6061 cgatgccctc gcccgtcacc cgcagcggca cctgccgccc ccgaacgtac agatgcagcc
     6121 gctccatgtc ggccgtcggc gacagccccg ccgccaccag cgccccgaac gtcacccgct
     6181 gccagcccgt ccgcgtcacc cgcagcttga cggccggctg cgccgccagc cactgctgca
     6241 cctccaggtc gccctgattc tccagcccag ccttgtgccg ggaagcggcc ttcctgccgg
     6301 tcggttcagc aacagccggt gcggcatcat cctcgatttg ccgccccagg cgggacgtgc
     6361 cgtgcccaag caaaggcgag ttcttcagta acgccagcgg cacggcttcg cgcgtctggc
     6421 gcagcaccac cggcccgtac cactgccgcg acccgtccag atcgtaagcc tccagccagt
     6481 agcttgcgcc gcccctcgcc agccgcaccg tctcatcgcg ccacgtgtac cgctgcccgg
     6541 ccgtcagggc atcactggtc agcagcgcgc tgccggcaac cagttccggc gtcaggcgtt
     6601 cgcgccgccc ctcccgctcg cgccagacgt gaaagcccag atgcgcgctt tcgtatcccg
     6661 tcgcccactg caccagcacg tcgccggtcg cgtagcgcgt cgcctcgaaa ccggtcaggt
     6721 caacttttgt gggggtcggt ggtggcgaac tgcctgtaca gccagtgcaa gtgccattcc
     6781 ggttcacagc caactcgcag agcggaccaa aggtgtaggt cgcccgttcc tgggtcgtat
     6841 tgccggtctc atcccgccag acggccgtcg tcccttccgg cgtcccgccc ggcgtccccg
     6901 tgacattcat cacacatggt gagcttccgg ttggcgaaac ccggatgacg tagaacagcg
     6961 aagcggcgct gttggcggca attgtgccgg gcgtccaggt gatgctcccc gaagtggcgt
     7021 cgttggccgg ctgggtaaac gtcccctggg ttgcctgcgc cccgccgtag gtggactcat
     7081 tggcgtagaa aactcctgtc acggtgggga tgtttgccac cacgcgccgc gtccgcgtgc
     7141 cgatggtcgt gccgtccagc acgatgtcat gatcggtcgg gttgacgatg tccacccgca
     7201 cccggtagaa ggtcgtctga ccgttacacg gtgggttcgg gccattcgtc ggattgccaa
     7261 tgtgaatcag gcgctgcgtc atgtagggct tgagtggtgc ggttgtggcc cccgcgtcac
     7321 ccggaaaata gacccggaac ttgtccccct gccgccagtt ggcaagagtg atgttgtcgc
     7381 cggaagtggt tggcacgagg gcgctgtggt tgccgatgta gtaggtgatg tggttagcgc
     7441 cgccgccgtt gatagtgatg ttgttactcc agataccgta gtccacggcg ctgacgctgg
     7501 tcgtccaggg accaacctca aagcttcccc acaccgttgc cccggagacc gtcgtggtgt
     7561 tgaaggtttg gctcccggtc cggctcgtga aggcaatcgt gccggtaccg ccgggggcat
     7621 cccagtcaaa gtcgttggcg cggcacgtac aaccgctggt gatgtagggg tagtagttcc
     7681 acgtaatggg aggttggcgc tcagtattct gcggaccaag atggatgccc ggatcaaagt
     7741 acatgttcag cccgcgaccg gtcgtgggac cacccaggtt ctgatcccgg ttggccccgg
     7801 gatcaagcgt gtgcgccgcc accccgaagg gattgacgcc gctattacct ccaccgggct
     7861 gaatgatgcg cagttcccag tgaccggccg ccggactggc caccgtgtag aagttcttcc
     7921 actggtcgtt ggcggctctg gtgtccggcc cgttcgtgcc gacggctgtg ttgtcgccct
     7981 cggtgaagtt cagacccgtg ccgctcagga tggtattgag cgaaatggac gtaccagagg
     8041 gatcgaacag ggaatagttt gttgttattg cccccacccg attgtcaaag cggttcactc
     8101 cggccggccc gcccgtcgag ccgtaatcag cgtcgtaaat gtcaatcgtc agccgcgagg
     8161 tgccgctcgg cacctcgatg aagaccgagt agtagctgtt gagacccggc gaagtcgaac
     8221 aacccacaaa atcaccattt gccaagggtg cgtcgctgtc gcgggtggtg atcatctgcg
     8281 cgttgagcgg ggttttggcg gcccgcactt ccggttttct gagagccggc ggaatccctg
     8341 ccaccaacaa cccaatcagg atgagtacgt aaagcggtct gaccgcggac cgaaaccagg
     8401 tggtgattct ctgcggtttc atggcatctt ctccaataca ggcttcaaaa aaggtttcca
     8461 ccgggcacac cgctgccgga gccgccagac ggccccggca agccgcgcgc ggcaggaacg
     8521 tggcggcaac accacgcacc ccagaatcgc ccggcgcggc acgacatcgg ttgcctgccc
     8581 ctgggcgtcg ccgcgcagta caaaccacgt gtcatcccac gtgccatcgg cagccggatg
     8641 catctcaaca atgcggtgtg caatgagtcg gtcgtccact tgcgccagaa cgacctcgcc
     8701 acactccggc cggtcatctg cactcagcgg ccggacggta atcgtctcgc cgtcggcaat
     8761 ggtcggcgcc atgctgcgcc ccggcgcggt gaaccgcacc ggcagtccct gcgccagaag
     8821 acttcggacc agcgttgtcc agccggcgtt ggtcacggct gcatcctccg tacgtagtcc
     8881 acaacggccg gcgtcggacg aaacacgagt tcgtaacagg gaacggccgt caccagccgc
     8941 tccagaaaac caaccgtgaa atcgagcgcc gcggcgtcat aaaaaggtgg aaaagcgcgg
     9001 gcaaacagcc gggccgccgc cagccccggc gtcagcgggc gggctgcgtc ttctgccccc
     9061 ttgcacaaaa tgaacaggcc gttgagaggc gcggcagccg gcgcggcaaa ctcgccttcc
     9121 ccgtgccacg gcgttccaaa catcagccac tgcccatcgc actggcggac gatgacccgg
     9181 tcatcactga gcaccgtcgc cccggcccgc gtccagagcc gggcggtcgt cgttttgccg
     9241 tcgccggact gcccgacaaa gagccacccg cgcccgtccg tatccaccac ggcgcaggcg
     9301 tgaagttcga cgccccgccc acgcgccagc aggttcgtca ccagcagctc atccacggga
     9361 tattccagcg gcgactgcat ggcggcgatg acggccggca ggcggcgata ccagacgtgg
     9421 ccggtctggt aggtcgggtc aaaccaggca atgcggtagg gttcagggcc aaaaaccggt
     9481 gaggcaatgt cgtagcgata accaccggcg gcccggtaca gcgtccacat cccgccggag
     9541 gcaaagacca gttccatcgg ctccggcagc ggcacggctt cgtccagcca gccaacgcgg
     9601 atcgccgcgt ccgccggcgc atcctcccac ggcacaacga agcgcgccgt cgggccgctg
     9661 atgtgcatgg gcaagtcgag tcccctggcg tccacggcca gccgcagccc gccaatcatc
     9721 aaccggattt gccgggaaca gagacgttca ggaagcaata gaactacacg ctatgggaaa
     9781 tgaacactga gcctgagctg gcccggcggt gctggcggtc ttgcaggccc ccagtacggc
     9841 ttcttcagcg cgcaactcga cccggacgat ggatggtttg gtgtagggac gccgcgccgg
     9901 cttttccggc acccccgaag ctgatgtgga tggtgaatgc ggttctgtca tggaatgcgg
     9961 tcctttcggt cgtgggaaac ggataagcat ggttggaacg ttatggtgtg ggttctgcta
    10021 caacgggacg tgcctgaagt accggcaagg cccggcggga ttggaaagtc agttcgacac
    10081 ccagttcctg cgcccgggcg cgcaaagctg ccacagaagc ctggatgtcc tcgtaacgct
    10141 cgcttcccgg acggtactcg cacagcgggt tgggcttcag atcaagccca agcaggtagg
    10201 cgcgcagatg attcgtccgg cagaagaaat ccacggcggc ttccttgtcg ccgttttcca
    10261 gttcgttgac ggccgcgcag ctcgtgcaca tgagacggat ttcacagctt gtgcacttgg
    10321 ccggacgggt ccgggtctga aggcgtaccc gccgcagaaa ctgctcccag ccctcgcgga
    10381 aactcccctg gcgcaggtcg taggtatcca cctgcgacag cacacagatg gacatttcgc
    10441 cgtacggatt cacggcaaag gaaccaacgc cgccgccgca gtcatagacg gtgttggaaa
    10501 cgtatggggc cacggcagcc gtccggtagc ggtcgttgag gtcgcgccag gcagtcatgc
    10561 ggcgcggatc gcgcaggtcc agctcgacga cttcctccgg cgtcaggcgc acctccagcg
    10621 gtgactgcga acagtcaacc cgtgggttga tcatgctgtc gaacttgaac ggcacgccca
    10681 gactttcggc aaaatcgcgc atggcgaaga tttcatctct ggtgatggtt gtgccgacgg
    10741 tcttgagctt gagcggcagc cggcgttcaa gcagcaggcg gatgccctgg tgacagcggt
    10801 cgtaggagcc gggcacgcgg gtcagccgct cgtaggtttc gcgggtgtgg ccgtagagcg
    10861 tgatctcgat ggcaaaggga cgccattcgg ccagatagtc ggcaatgcgc ggcgtcagca
    10921 gtgtgccgtt ggtaaacagc gtgatgatga agccccggcg cctggcttcg gtgtagatgt
    10981 ccagaaagtc ccggcgcgca aaaatttccc cgccggtaaa gagcacccac agcgttccgg
    11041 cttcggcaat ttcgtcgaaa atccgccggt attcatccag cgaaagctcg cgccgccggg
    11101 cggcgtggtc gttcattggc aggttgttgt agcagtgctg gcacaccagc ggacagcggc
    11161 ggctcacctc aaaggtggct tccagcggga tacgcccggc cagcagccgc ccgtgcaacc
    11221 ggcggctcag ttccgcgtaa gagacgcttt ccatggcttc cctctcaggc agccgagctg
    11281 gccgcgcaag gaacctcaat gatcccgctt tcctcaagtg cggccagaaa ttcagcgaca
    11341 tcctgcgcgg cctgttccgg tgacacctcg aaagcctcac agagcaccgc gccgagcgca
    11401 gctacgtctc cggttgtatc gagctgtgac cagagcaagg cggccgtgtc gttcaggacg
    11461 tagatggcat ccagatcagc cgcctgcccg cgaatcggga tcaacagggt ttcgtcggca
    11521 atgcggcgcg tcacacatgg aagttttttg acaaggttgc tcataagatt tttccagctt
    11581 ttgggttgtt tttatgggca tcacttcgta gccatacaaa gttgcaacgg tattgtgaca
    11641 ccttggcagc ctgaaacagt cccaaaaaaa gttctcacct cactcagacg cttctatcgg
    11701 caggggcgtc acatgccttt caaaattttt tgccttcggg cttgcgcaac gccacctgcc
    11761 agcgtcagaa acgccctgcc ccaggcgaaa ccgggcatga tggcttttga cttggctttt
    11821 cactggtgct tggtgagaat gggcgcttgt tttcgcgcgc cgccacggcg aatgctggtg
    11881 ggggatcgct tccaaatacg ttggatgacg ctcttaagga tgaccttgtt gatgtcttca
    11941 cgcctgttga cccgtctcgg tctggttctg atgttgtgcc tgcatccgtt gctgttgtct
    12001 ctcccgccca cgctggcgtc cggtggaaca ccacggccac tgcgcccttc ccaaccccca
    12061 gcgcacacca gaacggctcc gacaaccctt gcccttccgg gggctgcaca gtggcgtaca
    12121 ctcacactcg atgagcgggt gcgttaccgc cgggcgattg aacaggtcta ttggaaacgg
    12181 cggcgctggg aggccacgac acccaagccg gctttcgacc gtctcttttc ccagccgcaa
    12241 ctccgcgccc ttgtcgcaga cgaactgtgc cagcagcacg cactggacct gctctggcat
    12301 cacgcgccaa cgcccgccga actccacgcc gaagtcagcc ggatgatgcg ccactccaaa
    12361 caaccggaag tgttgcagga gctgtttgcg gcgctggaca acgactccat tgccattgcc
    12421 gaatgcctgg cgcggccggt gctggtcaga cagcggttgc aggcggacta tgcccgtgac
    12481 cggcggtttc acggccggct cgaagcccag gtgcgccagg cgctggaaat cgcgcccgcg
    12541 gttgagacgc tctcccggct gggcgcggtc tgcaccgaag tcgagttcat ccgccgtgac
    12601 cggcctgaag ccttcgcggt tgccgaccta cgccgcctgc cggtgtccgg cgcggactgg
    12661 gaacacgaaa tggcccggct tgcagaacgc ttcggaagcc acccggccaa actggcgccc
    12721 ggtatggtga cgcccctgtg tgaagacgac gagcggtttt tcattcagca gcttcaggcg
    12781 attgagagcg accgggtgcg gcttgtcaca gccgaatggc gcaaggtgga cttcgatacc
    12841 tggtgggcgc aggtcagggc caactacagc cccgtcatcc cgacagtctc cgggtcgttt
    12901 ccagaactcc gtgcgccggg cgcagtggaa agcggctttc ccgaggccat tgccggcaac
    12961 gacaaccgct gggcgcagga tgccggcgat ggtgtcccgt ccgcgcgttt ccgccatacg
    13021 gcagtctgga cgggcgtcga aatgattgtg tggggcggtt tccgggggac gttcagcggc
    13081 ggcagcccgc tcaacaccgg cgggcgctac aacccgatta ccgacacctg gacgccgacg
    13141 cgcgtcgccc ccagcgccat tggcgccacc gatgccgcgc cagcgccacg ggtcaaccat
    13201 acggccgtgt ggaccggcac gcggatgatt gtctggggcg gcgtcagcgg cacgccggtc
    13261 aactccggcg cactctacga tccggtcgaa aacaagtgga cggcgacccg taccgacccc
    13321 agttcatcca cggccaacga cggcgcaccg gccgcccggt tcagccacgt tgctgtctgg
    13381 ctggcgcagg ctgggcggat ggttgtctgg ggcggcaacc tcaactttgt cggcagcgtt
    13441 cccatcccaa ccaataccgg cggcgtctat aaccccgaaa ccaacgcctg gagcgccacg
    13501 gccacgacgg gcgcaccaca ggcgcggacc gaccacgtgg cggtttcgac cggaacggcg
    13561 atgattgtct tcggcggcgt caacgccgac ggcggccgcc tcaacagcgg cggcatttat
    13621 acgcccagca acaacacctg gacggcgaca agcacgacca atgcccccgg actgttcacc
    13681 cccagcgccg tatggacggg aacggaactt ctcgtctggg gcagcgtggc cggcgcgcca
    13741 gcgccaaccg tggccggtgc ccgttacaac ccggccaaca acacctggac agcgattgcc
    13801 acggctggcg cgccgacgcc ccgcgtcaac cagagtaccg tctggaccgg cacggaaatg
    13861 attgtctggg gcggggcggc gctcgacgta cgcttcaacg acggtggacg ctacaacccg
    13921 gcgacgaaca cctggacgcc ggtcacaacg gtcggcgctc cgtcgggacg tgaaaaccac
    13981 acggccatct ggacggatgc ctacgccgaa ccgaaccaga acgccacgaa gtacatgatt
    14041 gtctggggcg gacagggcgg cgacgccacc ggcggccgct atgatcccct cacgaacacc
    14101 tggcttccga cggcgaccac gcccgttccg atcgcccgcg aaggccacac agcggtcaac
    14161 accggcgtgg aaatgatcat ctggggcggt gcatcagccg gtgtgcggac gctgaccggc
    14221 gggcgctaca acctcgccac ggcccagtgg ctgcccacgt ccacccaggg cgcgcccggc
    14281 gcggcgatca acctgccgcc cgtgggccac accgccgtgt ggacaggcag cgaaatgatc
    14341 atctggggcg gacagaccaa cgccggcggg cgctacaacc ccgtcacgaa cacctggacg
    14401 cccacctcgc tgacgaatgc cccctcggca cgggaagaac acaccgccgt gtggacgggc
    14461 agtgaaatga tcgtctgggg cggacgtttc acgaatccgt ccaacaatga gaccaactac
    14521 tttgacaacg gcgggcggta caaccccgca acggatacgt gggcggcgac ggcagcggat
    14581 ggtcgccccg ggccgcgctc ccggcacacg gccgtctgga cgggcagcga aatgatcgtc
    14641 tggggcggcg tgacctttgc cgacaaccgc ttttccgaac tgcgcaccgg cggacgctac
    14701 aacccgacga cgaacacctg gacgcccacg cgcaccgatc cgaccagctc cggcgggacg
    14761 gacggcgcgc cggatgcccg ttttgaccac acggccatct ggacgggcga ccggatgatc
    14821 gtctggggcg gggcgaccac cgccgcccgg gcgttcaact ccggggcgct gtacaacccg
    14881 gctgccgaca cctgggcggc cacctccgcc aacggcgtac cgtcggcgcg ttccggccac
    14941 acagccgtct ggacgggccg cgaaatgatc gtctggggtg acgccggcgc caccggcgga
    15001 cgctacaacc cgacgttcga cttctggcgg ccggtcgaaa cggaaggcgc gccggatttg
    15061 accgccagcc acacggcaat ctgggacgcc acccgccggc agatggtcgt ctggggcgga
    15121 cgtggcagcg gcggcgtctc caacgcgctg ggggcgtatg gggcccgggg tgaacagggt
    15181 gacaccgtgg gcgtcttccg ccgggggcag tttttcctgc gcaactcgaa cacgtcgggc
    15241 aacgccgacc tggctttcac gtttggcgcg gagggcgacg tgcccctggc cggtgactgg
    15301 aacggcgacg gcatcaccac cgtcggggtc ttccgcaacg gcacgttctt cctgcgcaac
    15361 agcaacgaca gcggcgtggc cgacattgcc tttgcctacg gtggcgcgga ggacatcccg
    15421 ctggccggcg actgggacgg caatggcacg acgaccattg gcgtctatcg cccggcgacg
    15481 cggacgttct tcctgcgcaa caccaacacg gccggcaacc cggacatcgt cgtggtctat
    15541 ggcgaggaag gcgaccgccc gctggtcggc gactgggacg gcaacggcac gacgacggtt
    15601 ggcgtggtgc gcggcaacac cttcctgctg cgcaatgcca acaccggcgg cgatgccgat
    15661 ctggtgttca actttggcaa ccccgatgac aaggttgtgg tcggggactt cgacggcgat
    15721 ggcgtggata cggtcggcgt ctatcgcggg ctgacgttct tcctgcgcaa caccaacctg
    15781 cccggcacgg ctgacttcct gctggtctat ggcgcggatg gcgacgtgcc gcttgtcggc
    15841 aactgggacg ggcagttgta gcgcggaaca cctcgcggat gcggcccgtc aaccgggatg
    15901 ggcccgccct tcagctttcg atgacggcgg caatcggcac gcgccggccg cggccaaacg
    15961 ccttgggcgt caccttgatg ccgggtgcgg cctgctgtcg cttgtactcg ttgcggttga
    16021 tgagtctggc gacatactcg accgtggccc ggtcaaatcc ctcggccacg atttcatcca
    16081 gactctggta ccgctcgatg taccgctcca ggatggcatc gaggatgtca tagggcggga
    16141 gcgtgtcctg gtccgtctgg tcggggcgca gttcggcgga aggcggtttc gtgatggtac
    16201 gggtcgggat gaccacccga tgccggttga tgtaggccgc gaggcgatag acatcggttt
    16261 tgggtacgtc ggaaattgcg gccaggccgc cgcacatgtc gccatacagc gtgcagtacc
    16321 ccaccgccag ctccgacttg ttgccggtcg tcaacaccag cgcgcccgac tggttggaaa
    16381 aggccatcag ggtgacaccg cgcagccggg cctggagatt ttcctcggtc acgccatgcg
    16441 ggggaaagcc aaaggccggc gtcagcatct gcgtcatggc gctgacggct ggttcgatgg
    16501 gcacgacgtg gaagccgatg cccaggttgc gggccagttc ggcggcgtct tcaaggctgt
    16561 ggtcggaaga gtacttcgag ggcatcgcca ctccggtgac gttttccggc ccgagcgcct
    16621 gcacggccag ggctgccgtc acggccgagt caatcccgcc gctgaggccc accacggcct
    16681 ggcggaaacc gcacttgccc aggtaatccc ggatgcccag cacaagcgcg tcatggatgt
    16741 cagcgacttc gtcggtgatg cggggtgtga tgggcgccgg cagatcagcc agatcaacga
    16801 tgcggaggtc ttcctgaaag gcgtgggctt cgagcaccag ttcgccctgc gcatcgagca
    16861 ccagactgcg tccgtcgaac accagactgt cattgccgcc aacctggttg accagcacca
    16921 cgggcacctt cagggtgctg gcatgatggg ccagcatggc ctgccggagc gcccctttgc
    16981 cccggtgaaa cggtgaggcg gagacattga tgatgacctg cgccccctgc tcggccagtt
    17041 cgcggacggg atcgatgtcg tacaggtggg tgtcccagaa ctcgcggctg ttccaggcat
    17101 cttcacagac gcagaccccc agccgataac cgttccagcg gatgatttcc cgccgctcgg
    17161 acggctcgaa atgccgcgct tcgtcaaaga catcgtaggt gggcagcagc gtcttgtagc
    17221 ggatggcgcg cagttcgccg ccttcgagca gggcaacggc attgtagagc ggcttgccga
    17281 agtcatcggg attttccgcc acaaacccca ccagcagggc ggtgtccacg gtggcggaga
    17341 agcgcaccag gtcatccagt gcagccaggt tgcgcgcaat gaaagccggg cggtcgagca
    17401 ggtccagcgg ggggtatccc ggaatcgtca gttcgggaaa gacgaccaac cgggcgccct
    17461 gtaacgcggc tcgcatggcg tactggcgga ctttggccgc attggcgacg aaagccccga
    17521 ccatggtgtt gatttgggca agcgcaattt tcatggttat cctctggctc ggacggcgtg
    17581 caagggaaaa gcctgaattg tacacgccga tatgccgttg tcacggggtt gatattgtgg
    17641 tgtcccggcc gccggccaca agggaacgga cactaccggt ggcagatcaa gccgccccag
    17701 gcactatcag tcgtagaggg catcaaaaat cgcttgattt catgcggatg gctggctagt
    17761 ctcgtgcaga aatccgcttc acgacaaggg taaatcacat cattttgcgc attcgcgcta
    17821 gcaggaggat tcactgccat ggcggccaaa gctccaaaat ccacggcaac caaagccacg
    17881 accaaggcca aagccacagc tcccaaagag gaagcgccgg ccaaaaaggc gccggccaag
    17941 aaagcggcag ccaagccgat gaccaaaacc gaaattgtca accacttcgc cgaaaagttc
    18001 ggcttcccga aacagaaggt gcgtgaattt ttcgatgaac aggcccggct tgccgccgcg
    18061 caggccaaag tcggcttcac gattccaggg gtcgggaaac tggtggtccg ggaatacaag
    18121 gcgcgtgagg ggcgcaatcc acgcaccggc gaaaagatca aaatcaaagc ccggaaacgg
    18181 ctcaagttcg tcatttccgc cgccgccaaa aaagcggccg gtttcgagta ggcggaagcc
    18241 gcaccctcca gccgggtttg aatctcctgc ctgtggcgtg cggccacagg catttcgttg
    18301 tggagcgcac gctccccgga ttgctgccct gcgcttgggc acagtatgct cccggtggtt
    18361 tccctggcgg cgcgtgcgtg tcgtccaagg gcagccgacg cggtgctgtt accagtcggg
    18421 gtttccgtgc gctccacgcc tacctgtccc atcctgccgg gccgttaccg acgccgtggc
    18481 aactatctcc tgcactgtgg actgctggcc ctcatgtgcg cgctgttgcc tgggctggag
    18541 acgcctgtcc gggccagacc acgccagctt ccgacgacct tcgtgcgtct ttcaaccggg
    18601 cagggactct cacagagtac cgcccagtgc ctggcccagg acgcccaggg attcatctgg
    18661 gtgggcacgc aggatgggct caaccgctat gacggttaca ccttccgggt gtttcgcacc
    18721 gatccggccc aaccgtccag cctgagtgac aactacatca cggcgctgtg tgcggaccgc
    18781 agcggattgt gggtcggcac ccagcacggc ctcaaccggt atgatccggc acgggagacc
    18841 ttcacccgtt ttcaaccccg cgccggagac gaggccggcc tcgcacacga ccgcatcacg
    18901 gccctgcacc gcgatgcccg cggtgttttg tggattggca cgccgcgcgg actccaccgg
    18961 ctggacggtg agcgcctggt tcgcctggcc tcgccccccg cccccgcgga acagacggac
    19021 agcctcagcg tcatccgcgc tatcgcccat gacacaacgg gaaagctctg gctcggcacg
    19081 aacggcgggc tgtggtgttt cgacccggac accggggcat ccaccgtggt gctcggcgat
    19141 cagcgtgtcc tggcgctgca tttcgaccgt caggggcggc tctggctggc cggcgcggga
    19201 ttgacctgct ttgagccggc gcgcggccgg ttcacccggt ttctcccgga ccgtcaccgg
    19261 ccggacagcc tggcgagtga ccagacacgc gccctggccg aggaccgcca gggccggctc
    19321 tgggtgggca cctggggggc tggactcagc cgcctggacg atgaacggga gggcggacac
    19381 ttcactcact tccgacacca tccacgccag gcggacacgc tgggacacga cttcatctgg
    19441 cagatgatgc gcgaccaggc gggaacgctg tgggttggga ccgactttgg gggactgaac
    19501 caggtcgttg agcaacgctt catcgttcac gatgccaacc cggaccgccc cgatcacctc
    19561 accgatagcc tcgtctggtc actggtggaa gacccggctg gcaacctctg ggtgggcacc
    19621 aaccaggggc tgaaccggct ggacgcacgc gggcgcgtga cacgctaccc ggccggcgcc
    19681 caggccggcc aactccgcca tggcatcgta ggcgcgctgc tcgccacacg ggagggcacg
    19741 ctctgggtcg gcacggaacg gggtggactc catcgcctcg ccgcgccata ccgtcacttc
    19801 acccatctgc gtcaccagcc cgaccagcca accagcctga gtgacaactg ggttcacgcc
    19861 ctctgtgaaa cacgcgacgg gacactgtgg gtcgggacgc agcgcggtct cgaccgcatt
    19921 gatccgcaca cccaaaccgt tctggagcgg ctcccaccgc atcccgacga accccggctg
    19981 gatgccatct gggccattca ggaagacccc tccggcgcgc tctggctggg caccgaacag
    20041 ggcctccgcc ggtggcaccc cgtcacccac caggaaaacc gctatcagca cgatcccagc
    20101 cgcgccgaca gcctgaccca cgactgggtg ctgaccctgc acctcgaccg ccagggaaga
    20161 ctctgggccg gcacccccgg cggactcaac cgtttccagc ctgaccatgg aaacttcgtc
    20221 cgctacacca cggctgacgg actccccaac aatgtcatca acgccatcct ggaagacgat
    20281 gccgggcacc tctggctggg caccaaccag ggcctctgcc ggtttgatcc ccagaccgga
    20341 gcctgccgta cgttcgacac ccgggacgga ctgccggcca acgaaatcag cactgccgcc
    20401 cggtggcgcg acgccgccgg ctggctgcac tttggcacga ccgccggttt tttctcattt
    20461 catccctccc aggtcgtgga caacaccttt ctccccccgg tcgccatcac cagctttcgg
    20521 atttttgacc gccccatcac cagcttcgcc gcgacccagc gcctgacgct gacccaccgt
    20581 gagaacttct ttgcctttga gtttgccgcc ctgaatttca tcacaccgga gaaaaaccgg
    20641 tacgcctacc ggctggaagg ctttgaccgg gactgggtgg actgtggaac ccggcgctac
    20701 gccggttata cgaatctcga ccccggagac tacgtcttcc acgttcgcgc tgcgaacaac
    20761 gacggcaagt ggaacgagca gggactgcgc gtccacctgc gggtgctgcc gcccccctgg
    20821 cggacgggct gggcctatgc cctttatgcc ctcgccggac tggggctgat gacaggactg
    20881 taccgggcgc gggtgcgccg ctggcgtacc caggcggcct ggcgtgaaac gcagctccag
    20941 atgcaggccg cagaagccgc cgcccaggcg gcccagtccg cccgggaggc cgccgatgcc
    21001 cgcgcccggg ccgcggaagc ccaggcgcag gccaccgagg ttgaggcgcg ggccgcccgc
    21061 caactggccg cgcgcaaccg tgaactggaa gcccgcaacg cggaactcat tgcctcccag
    21121 cggcgggccg accgcatgtt ttccgccctg gcggacgccc ttcccggaac aaccctcgat
    21181 gacaaatacc ggctcgatga gaaaattggc gccggcggtt ttggcgctgt cttcagggga
    21241 acgcaccttg ggctgggtca cgccatcgcc gtcaaggtct tcaagcctgt cgccggaaac
    21301 gacagtgccg aggcgctgga acgcttccac cgtgaaggcg tcgccatttc acgccttgac
    21361 caccccaaca tcgtgcgcgt cctggactcc gggctgtccc acgacggcat tgcctatctc
    21421 gtcatggagc tgctgacggg acgcccgctc agccacgaac tgcccggacg cctgagcctg
    21481 ctgcggacca tcaggctgct gattcccgtt tgtcgcgccc tggctgaagc ccaccggcac
    21541 ggcatcatcc accgcgacat caag
//
