LOCUS       NZ_CP072646            20960 bp    DNA     circular CON 02-DEC-2024
DEFINITION  Chloracidobacterium sp. MS 40/45 chromosome 1, complete sequence.
ACCESSION   NZ_CP072646
VERSION     NZ_CP072646.1
KEYWORDS    RefSeq.
SOURCE      Chloracidobacterium sp. MS 40/45
  ORGANISM  Chloracidobacterium sp. MS 40/45
            Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia;
            Terriglobales; Acidobacteriaceae; Chloracidobacterium;
            Chloracidobacterium aggregatum.
REFERENCE   1  (bases 1 to 2667443)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Genomic and phenotypic characterization of Chloracidobacterium
            isolates provides evidence for multiple species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2667443)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2021) Department of Biological Sciences, Tokyo
            Metropolitan University, 1-1, Minami-Osawa, Hachioji, Tokyo 1920397,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu 1.8 assembler v. 1.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018304805.1-RS_2024_12_02
            Annotation Date                   :: 12/02/2024 00:41:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,029
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,951
            CDSs (with protein)               :: 2,951
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 7 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1438512
            Orig. end                         :: 1459472
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072646.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20960
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10960](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10960)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            885..2471
                     /locus_tag="J8C02_RS05945"
                     /old_locus_tag="J8C02_05945"
     CDS             885..2471
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012706.5"
                     /locus_tag="J8C02_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05945"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_211425141.1"
                     /transl_table=11
                     /translation="MPWHERTRRCWSWKLGWVLVAIGLMVWPGGCRRPVVLAADTLVMA
                     VEKPPKTLDPRVGNDAVSARLHQIIFDTLVNKNEQLDIVPELADFTISPDGRVFTFRLR
                     PGVFFHDGRPLTAEDVKYTFESMCAPTFNSPKKGDFALVEAIEAPDERTVVFRCRTPNL
                     PMLGSLVAVGIVPKGTSPEEAAQRPVGTGPFRVVTYRENHDIWLEANPAYFKGAPRLKR
                     LQIRFIPDAMTRELELRKGTVQLAVNADLAYSTNQALGKTPGLKLVQAKGTNIAYLGLN
                     CEDARLADVRVRRALALAIDRETIIRTVFRGMARPAAGPLPPEQWAYPEDLPPPRYDPE
                     EARRLLAEAGYGPGQPLRLELKTSSAELSRQVAAVLQEQLKRVGVELSLRSFEFQTFLQ
                     DTIAGNFQMFYLINVGANQSVDFLSYFYESSRIPTKAKGYSEGANRARYRSAEVDGWLR
                     AAAATTDKAEQRRLYGLVQKQVVSDVPQIFLWYPNNVAIAHERVQGITLELSGSYAFLR
                     QVWIAEGASQD"
     gene            2586..3152
                     /locus_tag="J8C02_RS05950"
                     /old_locus_tag="J8C02_05950"
     CDS             2586..3152
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006237746.1"
                     /locus_tag="J8C02_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05950"
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_246604569.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 3.8e-47,
                     bitscore: 156.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGSGQLKRVCVYCGSQTGQATAYREVAWSVGERLAQHGIEVVYG
                     GGHVGLMGVVAEAALSAGGRVIGVIPERLLEREVAYREVTEMYVTRTMHERKARMMELS
                     DAFVALPGGIGTLDELFEIWTWRQLGYHSKPVGLLNVAGYYDGLLGFLDRAVQEGFLTP
                     DCRDLLMVETDFGKLLARLSVTIIR"
     gene            complement(3087..3845)
                     /locus_tag="J8C02_RS05955"
                     /old_locus_tag="J8C02_05955"
     CDS             complement(3087..3845)
                     /EC_number="2.7.7.77"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024214.5"
                     /locus_tag="J8C02_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05955"
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="WP_281427950.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-27, bitscore:
                     94.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTNTGHDAGCQGLDDCPVYILAGGQSRRMEWPKALLPFPDVPLL
                     LVLVDRLRVASRCVYVVCSPVGFSAASDAVQITLSDYCFNGNVLVDPIPNGGPLGGVAC
                     AVEHTRQLGRPRCLVIPCDMPFLTTTFLARLASTHRTAPAVIPLTADGKPTGVCAAYNV
                     AILPALSAFLRQGGRRVRDFLQTIPAVPLPFPDYADLPGADRLLYNLNTPADYRQALLW
                     HQEARLENSLSDDSYGQPRQQFPKIRLDHQ"
     gene            complement(3928..4209)
                     /locus_tag="J8C02_RS05960"
                     /old_locus_tag="J8C02_05960"
     CDS             complement(3928..4209)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_05960"
                     /product="hypothetical protein"
                     /protein_id="WP_211421363.1"
                     /transl_table=11
                     /translation="MPAPDLSSLEKIQAELRRYEHPLLEFGAVEHPGGVQVSISLKVAD
                     ILEPYAFVIPHRDLQDPRYGWRFQNLLFNYIHDYMIETFTHTPHHIGT"
     gene            complement(4236..4982)
                     /gene="fabG"
                     /locus_tag="J8C02_RS05965"
                     /old_locus_tag="J8C02_05965"
     CDS             complement(4236..4982)
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-174). E-value: 3.7e-28. Score:
                     90.6. Matches aSDomain:
                     nrpspksdomains_J8C02_RS05965_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013407785.1"
                     /locus_tag="J8C02_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05965"
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="WP_246604570.1"
                     /sec_met_domain="adh_short (E-value: 2.8e-44, bitscore:
                     148.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.4e-33, bitscore:
                     112.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFRGKTILITGGSRGIGRAIALELAARSVNIAFTYHSRVEAARA
                     VEQELQALGVEAQAYQADAADFEAAQAVVRQVRERFGALHGLVNNAGMTRDKLLIMMKE
                     DDWDAVLDTNLKSVFNLSKAVVALLLKQKQGGSILNISSISGVIGMAGQTNYSAAKAGM
                     IGFTKALAKEVASRGITVNALAPGLIETEMTEGLSAEYRAKLLETIPLGRFGTATEIAR
                     IAAFLLSEDARYITGQVLCADGGLVM"
     aSDomain        complement(4461..4964)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8C02_RS05965_PKS_KR.1"
                     /evalue="3.70E-28"
                     /label="J8C02_RS05965_PKS_KR.1"
                     /locus_tag="J8C02_RS05965"
                     /protein_end="174"
                     /protein_start="6"
                     /score="90.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TILITGGSRGIGRAIALELAARSVNIAFTYHSRVEAARAVEQELQ
                     ALGVEAQAYQADAADFEAAQAVVRQVRERFGALHGLVNNAGMTRDKLLIMMKEDDWDAV
                     LDTNLKSVFNLSKAVVALLLKQKQGGSILNISSISGVIGMAGQTNYSAAKAGMIGFTKA
                     LAKEV"
     CDS_motif       complement(4506..4562)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8C02_RS05965_0002"
                     /evalue="4.90E-08"
                     /label="PKSI-KR_m4"
                     /locus_tag="J8C02_RS05965"
                     /protein_end="159"
                     /protein_start="140"
                     /score="25.5"
                     /tool="antismash"
                     /translation="ISSISGVIGMAGQTNYSAA"
     CDS_motif       complement(4899..4964)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8C02_RS05965_0001"
                     /evalue="2.20E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="J8C02_RS05965"
                     /protein_end="28"
                     /protein_start="6"
                     /score="23.5"
                     /tool="antismash"
                     /translation="TILITGGSRGIGRAIALELAAR"
     gene            complement(4991..5824)
                     /locus_tag="J8C02_RS05970"
                     /old_locus_tag="J8C02_05970"
     CDS             complement(4991..5824)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.5"
                     /locus_tag="J8C02_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05970"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_211425144.1"
                     /sec_met_domain="Abi (E-value: 1e-15, bitscore: 55.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLTEQGAMPPANPAPHLPVTGWNASAALVTWLLSMSAILLASI
                     GAQLGWTTWFYLQRATLPTQADLTASRSLTLTLVLSTFVAHGITLLWCWQLIRRTSPHG
                     VRLALGLDWYRPLWSRRGAFLLACGFAAPLFLAVGAWLERYLPNAKTDLDRILAQGPAI
                     RVAIACVAALSAPLAEEVVYRGIIFGGLQRRLGVRPTVVLVSLLFLAVHIPQYWGGWAG
                     LAMLALLSLTLTVLRAATGSILPSVMLHYAFNGIQAIAIVFFWELLETSPSTTTP"
     gene            complement(5808..6599)
                     /locus_tag="J8C02_RS05975"
                     /old_locus_tag="J8C02_05975"
     CDS             complement(5808..6599)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00530.1"
                     /locus_tag="J8C02_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05975"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_211425145.1"
                     /transl_table=11
                     /translation="MAAMKTIRILHSIVALLLIVLYTVAMGSLALLLSLFDRTGEYQHW
                     CARTWCRMIAFTVGMRVSIDGIAQLPRHTPAVVLANHQSLLDIPVLFAFLPFQFRILAK
                     KELFRIPFLGWFLWRAGHIPVDRGNRNATPDMIAAARKVLQARIPVVIFPEGTRNVQPA
                     RVKAFKSGGFRLAREAGVPIVPVTIHGTATFLPAHSMWLTPCPVHLTIHAPLDVTDLSI
                     EEAMTQVASTMNERLAALAQSHPQPSLPPSGKRYPAHDLSD"
     gene            complement(6587..8095)
                     /locus_tag="J8C02_RS05980"
                     /old_locus_tag="J8C02_05980"
     CDS             complement(6587..8095)
                     /EC_number="2.7.1.12"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012589.5"
                     /locus_tag="J8C02_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05980"
                     /product="gluconokinase"
                     /protein_id="WP_211425146.1"
                     /transl_table=11
                     /translation="MILAVDLGSSSFRAAVFTPDGRLQPETLARRPVAATTAPDGTMTY
                     DAAALFAGFTGVISRSLHMADRQGYVIRGVGISTMMHSLMGVRRVANAGPPDVGTPTTP
                     VFAWGDTRSEAERENLVEHFTRHQLYARTGCPLHSSYWLLKLAWLRRHLTLQEWQWMSF
                     ADYAWWRLFGQTCTTVSLASATGLYARREADWDEEILGYLGLERCHLPPVASDGWSLPG
                     TVLIPSFKRRWPQLHSARFFPALGDGACSNLGSLCFSDNRAAINIGTTAALRVTLPRER
                     EPEEPPPGLWVYHLDHGHALVGGALSNAGNLLAWGRRTLRLPAAPILEATLRQTMAEDT
                     GLTVLPFLAGERSLGWHPQATGMIAGLRLSTTPVAIWQALLEVIALRLAWMARELETAG
                     LLPDSTEIIVSGGVSSSPVFATMLCQALGRPICVIQTEASARGVALWVSLRLGLLTSDH
                     CPLPAGTWFQPDAATQARYRERLERHRATYLTMAESSFLQRWLR"
     gene            complement(8108..9097)
                     /gene="glk"
                     /locus_tag="J8C02_RS05985"
                     /old_locus_tag="J8C02_05985"
     CDS             complement(8108..9097)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: protein motif:HMM:NF014715.5"
                     /locus_tag="J8C02_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05985"
                     /product="glucokinase"
                     /protein_id="WP_211425147.1"
                     /transl_table=11
                     /translation="MTTTRYLLAGDVGGTKTHLGLFDAATLAMLETRTFASADFSDLPA
                     MLRSFFGGRALRCQAACIGAAGPVLDGVCRITNLSWSIRADELRQFLDCPAFVINDLEA
                     NGNGIALLSPSDFHQLQAGTPRLGNAALISAGTGLGECILFWDGTRHIAVPSEGGHASF
                     SPSDPTELDLLAYLWQTYDHVSWERLVSGTFGFAHLYHFFRDTGRAAGSAALEALAATD
                     GYGAAISKFADAGLPIAVAVMERFVTLYGAEAGNLALKALATEGLFIGGGIAPKILKWM
                     TGGGFLDAFVAKGRFRSFLEQVPVAVILNEQTALLGAARYAKHHAHLS"
     gene            complement(9112..9888)
                     /gene="ppgK"
                     /locus_tag="J8C02_RS05990"
                     /old_locus_tag="J8C02_05990"
     CDS             complement(9112..9888)
                     /EC_number="2.7.1.63"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0047330 - polyphosphate-glucose
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ppgK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011437870.1"
                     /locus_tag="J8C02_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05990"
                     /product="polyphosphate--glucose phosphotransferase"
                     /protein_id="WP_211425148.1"
                     /transl_table=11
                     /translation="MAKRALGIDIGGTGVKGAPVDLRTGTLTQERFRLLTPQPATPDAI
                     AETVFELIRHFGWSERDGAIGIGLPSVVKHGIAHTAGNIDPSWIGCDAATLFKNTTGYT
                     VTLLNDADAAGLAEMRFGAGRDLAGLVAVVTLGTGIGTALFHNGQLIPNTELGHLIIRD
                     KDAERRASLSAREQQNWSWKKWAGYVSEYLTELHRLLWCDAFVLGGGASNKFDKFAAYL
                     TCPAPVLPARMANLAGIIGAALATVPAAHARAKSPS"
     gene            complement(10001..10960)
                     /locus_tag="J8C02_RS05995"
                     /old_locus_tag="J8C02_05995"
     CDS             complement(10001..10960)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="J8C02_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_05995"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_211425149.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.2e-81, bitscore:
                     270.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.7e-69,
                     bitscore: 229.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTNVGSVAALDPFAGQVRLQTPDPAAVAAAYAYCREVTRTHAKS
                     FYFCTQTLPRHKRPAIYAIYALCRQIDDLVDTNRHASPMEVTLAVEAWSQALRDLYAAR
                     PFPSHPVLIAWYDFLPQFPVKSEHPLELMQGCLMDARAEGPVRFERFDDLYTYAYRVAS
                     LVGLMTSEVFGYGDPSALQYAVALGIAFQLTNILRDVGEDARRNRIYLPLEDLRRFGCT
                     EDMLLEGRLTPEVVALLKFEICRARDFYREAECGIRLLSPDSRFTVFLSSRLYGGILRD
                     IERHGYDVFSRRAHLSLGAKLWAVPPLWLRARLGGILT"
     gene            11189..12199
                     /gene="bchG"
                     /locus_tag="J8C02_RS06000"
                     /old_locus_tag="J8C02_06000"
     CDS             11189..12199
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bchG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01476.1"
                     /locus_tag="J8C02_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06000"
                     /product="(bacterio)chlorophyll synthase"
                     /protein_id="WP_211425150.1"
                     /sec_met_domain="ubiA (E-value: 3.3e-18, bitscore: 63.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSDAAATSPLLQTLLNHVQLLDPVTWLGPWQCFCCGVLATGLR
                     LSDLTLLDGVKFFLACGLIGPLLTGFSQSINDYFDRHLDAINDPERPIPSGRISLSAAR
                     ANFTLTGLLALGNMSLLYVITGSLLILILGIAGLFLAYAYSAPGFRLKENGWLGTTSVG
                     IGYCLVPWLLAAHLFSREPGFPSFHLALGVVNALVAMGLITMNDFKSIEGDRKNNLRTL
                     PVLYGERGAMLIAFAEINLAQVIFVITCFFFGYVTIGWLGMAFFVPQLIQQVQLYRAPH
                     DSRLLESIGRNAAGRSLVSQSQSGAHPGFIRFLVGSNLITVTALTAVSIVHGYWR"
     gene            12236..12430
                     /locus_tag="J8C02_RS06005"
                     /old_locus_tag="J8C02_06005"
     CDS             12236..12430
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_06005"
                     /product="hypothetical protein"
                     /protein_id="WP_211425151.1"
                     /transl_table=11
                     /translation="MKNTEPSTASDSTNQTSEASLAAFRTLSLPEKALTIAQAQATLFS
                     NTIVRALSTVLRGSRPSAG"
     gene            complement(12443..13291)
                     /locus_tag="J8C02_RS06010"
                     /old_locus_tag="J8C02_06010"
     CDS             complement(12443..13291)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (30-198). E-value:
                     1.3e-16. Score: 52.4. Matches aSDomain:
                     nrpspksdomains_J8C02_RS06010_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF027681.5"
                     /locus_tag="J8C02_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06010"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_211425152.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.5e-12, bitscore:
                     43.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.8e-15, bitscore:
                     52.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQDWLVTGGTGYLGVHVAAALGATVAGRRQGLGLFTPALADALA
                     HHRVIVHLAAHVAKAPEEAAACFEVNSDGTRWLCARLTEQHTLLLASTKDVYGAHADHY
                     AAVPESCPTTLHGQNAYAWSKWLAEEYARFYAARRGFRLCVLRLSTVFAPPTPGNPGGL
                     VSRFAHAIRHGQPLTLRWQGRQVRDVLPVAELVNVLRACVASSVGHDTFNIGGGPAYAF
                     PLAELAQRIGRVCGTPPVLHLTDTEPPPDDQRRYVSDLSKASGQLGWEPRFDLDAALKW
                     A"
     aSDomain        complement(12698..13201)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8C02_RS06010_NAD_binding_4.1"
                     /evalue="1.30E-16"
                     /label="J8C02_RS06010_NAD_binding_4.1"
                     /locus_tag="J8C02_RS06010"
                     /protein_end="198"
                     /protein_start="30"
                     /score="52.4"
                     /tool="antismash"
                     /translation="QGLGLFTPALADALAHHRVIVHLAAHVAKAPEEAAACFEVNSDGT
                     RWLCARLTEQHTLLLASTKDVYGAHADHYAAVPESCPTTLHGQNAYAWSKWLAEEYARF
                     YAARRGFRLCVLRLSTVFAPPTPGNPGGLVSRFAHAIRHGQPLTLRWQGRQVRDVLPVA
                     ELVNV"
     CDS_motif       complement(13154..13276)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8C02_RS06010_0001"
                     /evalue="5.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="J8C02_RS06010"
                     /protein_end="46"
                     /protein_start="5"
                     /score="9.4"
                     /tool="antismash"
                     /translation="LVTGGTGYLGVHVAAALGATVAGRRQGLGLFTPALADALAH"
     gene            complement(13288..14487)
                     /locus_tag="J8C02_RS06015"
                     /old_locus_tag="J8C02_06015"
     CDS             complement(13288..14487)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="J8C02_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06015"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_211425153.1"
                     /transl_table=11
                     /translation="MEEPVATATPSVGLKRRVLVVDDEAEIRLFFQDFLSSCQVCTAAD
                     GSEVAPLLASFRPHLVITDLRMPRQGGLAVVELVKAHDPAIEVLVITGYGRIEEAVEAM
                     KLGASDFIPKPFEVGQMHLAIEKCFERVMLRQQNTALQHANRELQRLTELKEKFLRMTS
                     HELRGPLTILQGYCDLLAVMADSPDDVREARTAMQVAISNLTTIVQNLTLLMTTTSDYL
                     PIDSQPFDVMALVRATLEEIRVHAMHRQHQYHLAGPEHLPAVGDALRVTQVLRELLFNA
                     VKFTPDHGNISVRLTSDEQHFTIEVEDDGIGMATHEVAVAFESFYEVASTQYHSTSRTN
                     FKGGGLGIGLTLVRDVVTAYGGRVSIVSEPGKGTTVTVQFPRHSRPPSGMETARTGDPA
                     "
     gene            complement(14487..15719)
                     /gene="coaBC"
                     /locus_tag="J8C02_RS06020"
                     /old_locus_tag="J8C02_06020"
     CDS             complement(14487..15719)
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /GO_function="GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA]"
                     /GO_function="GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaBC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011524575.1"
                     /locus_tag="J8C02_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06020"
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="WP_211425154.1"
                     /sec_met_domain="Flavoprotein (E-value: 4.1e-36, bitscore:
                     120.8, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKHITLGVTGCIGAYKAILVLRGLQQLGATVEVVMTESATRFIQ
                     PLTFQALSGKPVYTSHWGRDDDTEIAHIALAQRTDALVIAPATANCLAKLAHGIADDFL
                     STVYLAATCPTFVAPAMNVEMWRHPATQENLARLRARGVRIIEPEAGFLACGMVGDGRL
                     ADPAGIVGTVWTSLAAQETTPRDLTGNHVLVTAGPTIEDIDPVRYLTNRSSGKMGYAVA
                     RAAHARGATVTLISGPTRLSPPEGVETIAVRSTREMYDAVLRYLPAATLVIKAAAVCDY
                     RPRQVAVEKLKKTQSPLRQLDLEPTEDILAAVGARKGSRFVVGFAAETGWSREAALEKL
                     RRKGADLLVFNDVTEAGAGFDTDTNRATFVLATGETRALPLMTKDELAHEILNLARPPQ
                     PVVHPQTQERM"
     misc_feature    15798..15809
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            15876..16928
                     /gene="glpX"
                     /locus_tag="J8C02_RS06025"
                     /old_locus_tag="J8C02_06025"
     CDS             15876..16928
                     /EC_number="3.1.3.11"
                     /GO_function="GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="glpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014099733.1"
                     /locus_tag="J8C02_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06025"
                     /product="class II fructose-bisphosphatase"
                     /protein_id="WP_211425155.1"
                     /transl_table=11
                     /translation="MSTESSETRFSPLSKEFLHVVEVAAIAAARTMGFGQRKQSDRAAV
                     EAMREAMRTVRMNGRIVIGEGERDKAPMLYIGERVGAGAEHPDDDERFPAVDIAVDPLE
                     GTNLCATGAANAIAVLAAAERGGLLHAPDMYMNKLVVGPAAKGQLDIDAPVAENLRILS
                     ACLRRAVTDLVVSVLDRPRHAKLIADLREAGARIQLISDGDLSAGISAAVGGSGVHAVM
                     GIGGAPEGVLTAAAMKCLNGEIQARFVLKDQLHAEDHTKVTEDSETLARMQAMGIADPA
                     RVYRTDDLAPGKHIIFAMTGVTNGNVLRGVRFFGAGKRTASLLMTTCPHTVRLVDTVHV
                     EGGPDTVIRL"
     gene            17189..18787
                     /locus_tag="J8C02_RS06030"
                     /old_locus_tag="J8C02_06030"
     CDS             17189..18787
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025006.5"
                     /locus_tag="J8C02_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_06030"
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="WP_211425156.1"
                     /transl_table=11
                     /translation="MRHLFRGFFAGWLCLALGVTLAQATERSEGCAVAGVVTDHRGSPI
                     AHAIVSIFRDGDEKEVLVTASSDRSGRFSLARLTPGVYRLLAAARGFQTLISEPTALAP
                     GQTSQMRLTLRPAPDARATGVNPVKYQNRRNRGIFNATASETPDAGRPGAPLWQGTALI
                     GSTGYDSQVTAEVTPGMDVGAYLRRDWEGQSVTIGGALRYSTGQHRGRIRWQTDQVTAD
                     PIMSSPMSSPAAPVPGGPFFRHDLQAADAWQITDRLQVLYGFDYLRAGRSHEDVWRPRL
                     AAHWSPCPAVQVHTALTSDGQAFPAWVDPERPLLTDDFPTPPARLALVDERPVLARNLR
                     VEAGVAWQMDARTTVKVYAYQDWLDGHPLAMEGHVMSRLEGRAQGTAIILTRRLRPRLA
                     VTTGYAAGRTATRPEDAGLAASTWLPGTYHVLTVVAETVFPGPETQIQVGYRSAWGHPV
                     HAIDPFTGRLPFTDAGLNFRIIQALPGWMFLPGRWEAVIEGRNLDERRSEVTGLGAAFG
                     FPHRRTVRGGLRFRF"
     misc_feature    complement(18941..18955)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(19330..19341)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(19649..19669)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.16"
                     /tool="antismash"
     misc_feature    complement(20405..20419)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 cgggacgatt gccacgggct ttgcgaccgg ttcggcggcg gatgaagtca atgcgcgggt
       61 cggggaaatc ctggtgacga ccgggcatgc gcaggacggg cggcagttgc tgtgggaagg
      121 gtttgccggg caggacgggg agtttacgac ctacctgttt cactacgcgc cggtggcaga
      181 catcgggcgg ctgtcgttgc tggcgttgtt tgagacgtac tttgagacgt tgccccagta
      241 caagcggccc ggagcggggt ttgcatttcg gcggccggtg ttcgggtaca ttccggggct
      301 gcaccacgtg ggtctggggc cgcagaagcg gacggcggcg caccgggtgt tgctgctggg
      361 ggatgcggcg tcgttgaatt cgccgctgac gttttgcggt tttggttcgc tggtgcggaa
      421 cctgcggcgg atcacgcatc tgattgactt ggcgctcaag gggcagcatc tggatgaggc
      481 gtcgttgcgg ctcatcaacg cctacgagcc gggcgtggcg attatggcgg cgtttacgcg
      541 ctacatggtg gccgatgagg gggaggaccc gaaggccgtc aacgagttgc tcaacatcgt
      601 catggaggcg ctgcatcagt tgccgccgtc ggtacggacg ggactgttcc aggaccggat
      661 ggcgtggggg gattttgtga agctgatgtt gcagatgcag aagctgcatc cgaacatctg
      721 ggaagccgta ccgcgcaagt tggggatggt ctatacgtcg gcctgggtgc tgaacttcgt
      781 ggagttttct gcctttgccc tgcagaagga gttggccggg gtgatggggc agcttgggcg
      841 ggggctgcgg gaggattttt acaactacgc caactattac cgttatgccc tggcatgaac
      901 gaacgcgccg gtgctggtcc tggaaactgg gctgggttct ggtggcgatt gggttgatgg
      961 tctggcccgg cgggtgtcgg cgtccggtgg tgctggcggc cgatacgctg gtgatggcgg
     1021 ttgagaagcc gccgaagacc ctggacccac gggtggggaa tgatgccgtt tcggcacgcc
     1081 tgcaccagat catcttcgat acgctggtca acaagaacga gcagcttgac attgtcccgg
     1141 agttggcgga cttcaccatt tcaccggatg ggcgggtgtt caccttccgg ctgcggcccg
     1201 gggtgttttt tcacgacggc cggccgctga cggccgagga cgtgaaatac accttcgaga
     1261 gcatgtgcgc gccgacgttc aactcgccca agaaggggga ctttgcgctg gtggaggcca
     1321 tcgaggcccc ggatgagcgg acggttgtgt ttcgctgccg gacgccgaac ctgcccatgc
     1381 tgggcagtct ggtggcagtg gggattgtgc cgaagggcac gtcgccggag gaagctgccc
     1441 agcggccggt cgggacgggg ccgttccggg tcgtgactta ccgggaaaac cacgacatct
     1501 ggctggaggc caatccggcg tacttcaagg gcgcaccccg gctgaagcgg ctacagattc
     1561 gcttcattcc cgatgccatg acccgtgagc tggagttgcg caaggggacg gtgcagttgg
     1621 cggtgaacgc tgatctggcc tacagcacca accaggcgtt ggggaagacg ccggggctga
     1681 agctcgtgca ggcgaaaggg acgaacattg cctatctggg actcaactgc gaggacgccc
     1741 ggctggcaga tgtacgggtc cggcgggcgc tggcgctggc gattgaccgg gagacgatca
     1801 tccgcacggt gtttcggggc atggcgcggc cggcggcggg gccgctgccg ccggagcagt
     1861 gggcctaccc ggaagacctg ccaccaccgc gctacgaccc ggaagaagcc cggcggctgc
     1921 tggcggaagc ggggtatggc ccggggcagc cgttgcggtt ggagctgaag acctcgtcgg
     1981 cggagttgtc gcggcaggtg gcggcggtgt tgcaggaaca gctcaagcgg gtgggggtgg
     2041 agttgtccct gcgctcgttt gagtttcaga cgtttttgca ggacaccatc gcgggcaatt
     2101 tccagatgtt ttatctcatc aacgtcgggg ccaaccagag tgtggatttt ctgagttact
     2161 tctacgagtc gtcccggatt ccgacaaagg caaagggcta cagcgagggg gcaaaccggg
     2221 cgcgctatcg gtcggcggaa gtggatggct ggctgcgggc ggcggcggcg accacggaca
     2281 aggctgagca gcggcggttg tacgggctgg tgcagaagca ggtggtgagc gacgtgccgc
     2341 agatttttct gtggtatccg aacaacgtgg cgattgccca cgagcgggtg caggggatta
     2401 cgctggagtt gtcggggagt tacgcctttt tacggcaggt gtggattgct gagggggcat
     2461 cgcaggattg ataccttcgt ctgataacgt aaagagggtg ccagacaaca gggacggcag
     2521 gcacggcagg taaagcaaga aaaaaagcag gaaaaacagc aagccggaga gggaggaagg
     2581 gaggcttgaa cgggtcgggt caactgaagc gggtttgtgt ctattgtggg tcgcaaaccg
     2641 ggcaggcaac cgcctatcgg gaggtggcct ggtcggttgg ggagcggctg gcacagcatg
     2701 gcatcgaggt cgtctatggc ggcgggcacg tgggcctgat gggcgtggtg gcggaggcgg
     2761 cgctgtcggc cgggggacgg gtcatcgggg tcatcccgga gcggctgctg gagcgtgagg
     2821 tggcctaccg tgaggtgacg gaaatgtacg tcacgcggac gatgcacgag cggaaggcgc
     2881 gcatgatgga gctgtctgat gcgtttgtgg ctttgccggg cgggattggc acgctggatg
     2941 agttgtttga aatctggacc tggcggcagc ttggttatca cagcaagccg gtgggactgc
     3001 tcaatgtggc cggttactat gatgggctgc tgggctttct cgaccgggcc gtgcaggagg
     3061 gatttctgac gccagactgc cgggatttac tgatggtcga gacggatttt gggaaactgt
     3121 tggcgcggtt gtccgtaact atcatccgat aacgaatttt ccagccgggc ttcctgatgc
     3181 cagagcaggg cttggcgata gtcagcgggc gtgttgaggt tgtaaagcaa ccggtcagcg
     3241 ccgggcaggt cggcgtagtc cgggaaggga agtggcactg cggggatggt ctggaggaaa
     3301 tcccggacgc gccggccgcc ctggcgcagg aaagcggaca gggccggcag aatggcaacg
     3361 ttataggcgg cgcagacgcc ggttggtttt ccgtcggccg tgagggggat gaccgccggg
     3421 gccgtgcggt gggtgctggc gagccgtgcc aggaaggtcg ttgtcaggaa cggcatatca
     3481 cacgggatga cgagacagcg cgggcgtccg agctggcggg tatgttcgac ggcgcaggcc
     3541 accccgccga gcgggccgcc attagggatg gggtcaacca ggacgttccc gttgaaacaa
     3601 tagtctgata acgttatctg aacagcatca gaggcggccg agaaaccaac cggcgaacac
     3661 acgacataca cacaacggga agccacccgc agacgatcaa ccaaaaccag cagcagtggg
     3721 acatcgggga aaggcagcaa agcctttggc cactccatac gccgactctg cccgcctgca
     3781 aggatgtaca ccggacaatc gtccagtccc tggcaaccgg catcatgacc agtgttggtg
     3841 tgcattctgg tttgtgctga atctaacgct gtgatgcctg tagcgaccgg ggccgctacg
     3901 gggcctgcgt ttgcgcccgt gctttaccta agtcccgatg tggtgtggcg tgtgggtgaa
     3961 ggtttcaatc atgtagtcgt ggatgtagtt gaacagcagg ttctgaaacc gccatccata
     4021 gcgtgggtcc tggagatcac ggtgtggaat gacaaaggcg tagggctcca gaatatccgc
     4081 caccttgagc gagatgctga cctgaacgcc accgggatgc tctacggccc cgaattccag
     4141 cagcggatgt tcataacggc gcagctcggc ctggattttt tcgagactgg agagatcggg
     4201 cgcaggcatc agcactttct cctgtcctga cagcttcaca tgacgagacc accgtcggca
     4261 caaagaacct gtccggtgat gtagcgggca tcttccgaaa gcagaaaggc ggcgatgcgg
     4321 gcaatttccg ttgccgtccc gaaccgtcca agggggatgg tttcaagcag tttggcgcga
     4381 tactcagccg acagcccttc cgtcatctcc gtttcaataa gacccggcgc aagagcattg
     4441 accgtaatgc cccggctggc gacttccttg gccaatgcct tggtaaaacc gatcattccg
     4501 gccttggcag cggagtagtt cgtctggccg gccataccga tcacgccact gatggagctg
     4561 atgttcagga tggaaccgcc ctgcttttgt ttgagcagga gcgcaaccac cgctttggac
     4621 aggttgaaga cacttttgag attggtgtcg agaacggcat cccagtcgtc ttccttcatc
     4681 atgatgagca gcttgtcgcg ggtcatgccg gcattgttga ccaacccgtg gagagcgcca
     4741 aagcgttccc gtacctgtct gacaacggct tgggctgctt caaagtcagc ggcatccgcc
     4801 tggtaggcct gggcttcgac acccaaggcc tgaagttcct gctcgacggc ccgggcggct
     4861 tccacccgac tgtggtaggt gaaagcgatg ttgacactgc gggccgccag ttcaagggcg
     4921 atggcgcggc caatgccccg tgagccgccg gtgatgagga tggtcttacc gcgaaaactc
     4981 atggcgttgt tcatggcgtt gtggtggagg gggaagtttc aaggagttcc cagaaaaaca
     5041 caatggcaat ggcctgaatg ccattgaagg cgtagtggag catgaccgaa ggcaggatgg
     5101 aaccggttgc ggcccgcagg acggtcaggg tgaggctgag cagcgccagc atggccagcc
     5161 cggcccagcc gccccagtac tgcggaatgt gcacggccag aaacagcagg gagaccagaa
     5221 ccaccgtagg acgaaccccc agacggcgct gcaacccgcc gaagatgatc ccacgataga
     5281 caacctcctc ggccagtggc gcggacaacg cggccacaca ggcaatagcc acccgaatcg
     5341 ccggcccctg ggcaagaatg cggtcgaggt cagttttggc gttgggaagg tagcgttcca
     5401 gccaggcgcc gacggccaga aacagcggcg ctgcaaatcc acaggccagc aggaacgccc
     5461 cccgccggga ccagagcggg cggtaccagt ccagccccag tgccaggcga actccgtggg
     5521 gcgatgtccg gcggataagt tgccagcacc acagaagcgt tatgccatgg gcaacaaacg
     5581 tggacagcac cagggtcagg gtcagcgagc gcgaagccgt caggtcagct tgcgtcggaa
     5641 gggtggcccg ctgcaggtaa aaccaggttg tccagccaag ctgcgctccg atggaagcca
     5701 gcaggatggc gctcatgctt agcagccacg tcaccagagc cgcgctggca ttccagcctg
     5761 ttactggaag gtgtggcgcc gggttggccg gaggcatggc accctgctca gtcagagagg
     5821 tcatgggcgg ggtaacgctt tcccgaaggc ggcagggatg gttgggggtg ggactgggcc
     5881 agggccgcca gccgttcatt catcgtggag gccacctggg tcatggcctc ttcaatggaa
     5941 aggtcggtga catccagcgg tgcgtggatg gtgagatgaa ccgggcaggg ggtcagccac
     6001 atggaatgcg ctggcaaaaa tgtggcggtg ccatgaatgg tgaccggcac aatcggtaca
     6061 ccggcttcac gagccaggcg gaaacctcct gatttgaacg ctttgacccg ggcgggctgg
     6121 acgttccgcg taccttcggg aaagatgacc accggaatcc gggcttgcag caccttccgc
     6181 gctgccgcga tcatgtccgg ggtggcattc cggttgcccc ggtcaaccgg aatatgtccg
     6241 gcacgccaga gaaaccagcc caaaaaggga atacggaaca gttccttttt ggccagaatc
     6301 cgaaactgaa acggcaggaa ggcaaacagc accggaatgt cgagcaggct ctggtgattg
     6361 gccagaacta ctgccggggt gtgccggggc agttgcgcga taccgtcaat ggagacccgc
     6421 atgccaaccg tgaaggcaat catccggcac caggtacgcg cgcaccagtg ttgatactct
     6481 cccgttctgt caaaaagtga caacaggagc gccagagacc ccatggccac ggtgtagagg
     6541 acaatcagca gaagcgcgac aatcgagtgg aggatacgga tggtcttcat cgcagccatc
     6601 gttgaaggaa tgaactttca gccatggtca ggtatgtggc gcggtgacgc tccagccgtt
     6661 cccggtagcg ggcctgggtg gcagcgtccg gctgaaacca tgttccggca ggcagcgggc
     6721 agtggtcact cgtcaacagc cccaggcgga ggctgaccca cagggccacg ccacgggctg
     6781 aagcttccgt ctggatgaca cagatgggcc gccccagcgc ctggcacagc atcgtagcaa
     6841 aaacgggtga agacgaaaca ccaccggaga cgatgatttc cgtggaatcc gggaggagtc
     6901 cggcggtttc cagttcccgg gccatccagg ccaggcggag ggcaatgact tcgagcagtg
     6961 cctgccagat ggcgacgggc gtggtggaga ggcggagtcc ggcaatcatt ccggtggcct
     7021 gcggatgcca gcccagactg cgttcgccgg ccaggaaggg caggacggtc aatccggtat
     7081 cttccgccat ggtctgccgc agggtggctt cgaggatcgg cgcggccggc aggcgcaggg
     7141 tacgccgccc ccaggcgagc agattgccag cgttgctcag cgcgccccct acgagggcat
     7201 gcccgtggtc aaggtgatag acccagagtc ccggcggcgg ttcttccggc tcacgttccc
     7261 ggggaagggt cacgcgcagg gcggccgtgg ttccgatgtt aatggcggcc cggttgtcgg
     7321 aaaaacacag gctgcccagg ttgctgcagg cgccatcgcc aagcgcgggg aagaaacggg
     7381 cactgtgcag ttgtggccag cgtcttttga aggacggaat gagtaccgtg ccgggaagtg
     7441 accagccatc gctggccacc ggcggcaggt ggcagcgttc aagtccaaga tagccaagga
     7501 tttcttcatc ccaatccgct tcgcggcggg catagagacc ggtcgccgag gcaagggaaa
     7561 cggtggtgca ggtctggcca aagagccgcc accaggcata gtcggcaaag gacatccact
     7621 gccactcctg gagcgtcagg tgacgccgca gccaggcgag tttgagcaac cagtaactgc
     7681 tgtggagggg gcaccccgtc cgggcgtaga gctggtggcg ggtgaaatgc tcaaccaaat
     7741 tctctctttc ggcttcggaa cgtgtgtcac cccaggcaaa aaccggtgtc gtcggcgtgc
     7801 cgacatccgg tggaccggca ttggccaccc gccggacgcc catgaggctg tgcatcatgg
     7861 tggagatacc gacaccccgg atgacgtagc cctggcggtc ggccatgtgg agtgaccggc
     7921 tgatgacccc ggtgaagccg gcaaagagcg ccgccgcgtc gtaggtcatg gtgccatccg
     7981 gcgcggtggt ggccgcaacc ggccgccggg caagggtttc cggctgcaac cggccgtcag
     8041 gcgtaaaaac tgcggcgcgg aaggatgagg aacccagatc aacggccaga atcatgggcg
     8101 tcccggctca ggaaaggtgg gcatggtgtt tggcatagcg ggccgcgccg agcagtgccg
     8161 tctgctcatt gagaatgacg gccaccggca cttgttccag aaagctccga aaacgcccct
     8221 tcgcaacaaa ggcgtccaga aaaccgcctc cggtcatcca cttgaggatt ttgggcgcaa
     8281 tgccgccgcc gatgaacagc ccctcggtgg ccagcgcctt cagggccaga ttgccggctt
     8341 cagcgccata gagggtgaca aaacgttcca tcaccgccac ggcaatcgga agacctgcat
     8401 cggcaaactt cgagattgcc gcgccgtagc catcggtggc ggccaaagct tccagcgcag
     8461 cggaaccggc agcgcgcccc gtgtcgcgga aaaaatggta caggtgcgca aagccaaagg
     8521 tcccggacac cagccgctcc cagcttacgt gatcgtaggt ctgccagagg taggcaagca
     8581 ggtccagctc ggtcgggtca ctgggggaaa aactggcgtg gccgccttcg gagggaacgg
     8641 caatgtgacg ggtgccgtcc cagaacagaa tgcactcgcc gaggcccgtc ccggccgaga
     8701 tcagggccgc attgcccagg cggggtgtgc cagcctggag ttggtgaaaa tccgacggcg
     8761 acagcagggc aatcccgttg ccgttggctt caaggtcgtt gatgacaaag gccgggcagt
     8821 caagaaactg acgcagttca tcggcacgga tgctccagga caggttggtg atccggcaca
     8881 cgccatcgag gacggggcca gccgcaccaa tgcaggcggc ctggcagcgc agcgcccgcc
     8941 cgccaaaaaa tgaccgcagc atggccggca ggtcgctgaa atcggcgctg gcgaaggtcc
     9001 gggtttcgag catggcaagg gtggcagcgt caaacagccc cagatgggtt ttcgtgccgc
     9061 ccacatctcc ggccaggaga taacgggtcg tggtcatcgt gtatccaggg ttcaggaggg
     9121 tgatttggct ctggcatggg ctgccgggac agtggccagc gcagccccga tgatcccggc
     9181 aaggttggcc atccgggccg ggagcaccgg cgccgggcag gtcaggtacg ctgcaaactt
     9241 gtcgaacttg ttgctggcgc cgccgccgag aacaaaggca tcacaccaga gcagacgatg
     9301 caattcggtg aggtattcgc tgacataccc ggcccatttt ttccatgacc agttctgctg
     9361 ctcacgtgcc gacagcgaag cccggcgctc ggcatccttg tcgcggatga tgaggtggcc
     9421 cagctcggtg ttgggaatga gctgcccgtt gtggaaaagt gcagtcccga tgccggtgcc
     9481 cagggtgacg acggccacca gtccggcaag gtcgcggccg gcgccaaagc gcatttcggc
     9541 caggccggcg gcgtcggcgt cattgagtaa cgtcaccgtg tagccggtgg tgttcttgaa
     9601 cagggtggca gcgtcacagc ctatccagga cgggtcaatg ttgccggccg tgtgcgcaat
     9661 gccgtgcttg accacggaag gcagcccgat gccaatggcg ccgtcacgct cactccatcc
     9721 aaagtggcgg atgagctcaa aaacggtttc ggcgatggca tccggtgtgg ccggctgtgg
     9781 cgtgagcaga cggaaccgtt cctgggtgag cgtgccggtg cggaggtcaa ccggcgcgcc
     9841 tttgacgccg gtgccgccaa tgtcaatacc caaggcgcgt ttggccatgg tttgcggact
     9901 cctttcgggg ttggggaagt ccggtgggag cgatgggaag ccggaggtgg ttctggcggg
     9961 gggggggttg cgggagacgc ttggagtccg ataatcagcc ttatgtcaaa attccaccca
    10021 accgcgcccg taaccacaac ggcggaaccg cccacaactt cgcccccagc gacagatgcg
    10081 cccgccggga aaacacatcg tagccatgcc gctcgatgtc gcgcagaatt cccccataca
    10141 aacgactgct gagaaacacg gtaaagcgac tgtccggcga aagcaaccgg ataccacact
    10201 cggcctcacg gtagaagtcc cgcgcccggc aaatctcgaa cttgagcagc gccaccacct
    10261 ccggcgtcag acgcccctcc agcagcatgt cctccgtgca gccaaaccgg cgcaggtctt
    10321 ccagtggcag ataaatgcgg ttgcgccgcg catcctcgcc cacatcccgc aggatattcg
    10381 tcaactgaaa ggcaatgcca agcgcgaccg cgtactgaag cgcactcgga tcgccgtagc
    10441 cgaacacctc actcgtcatc agccccacca gcgaagccac ccggtaggcg taggtataaa
    10501 ggtcatcaaa ccgctcgaag cgcaccggac cttccgcccg ggcgtccatc aggcagccct
    10561 gcatgagttc aaggggatgt tcagatttga ccggaaattg cggaagaaag tcataccaag
    10621 cgatgagcac cggatgggac ggaaagggcc gtgcggcata cagatcgcgt agcgcctgtg
    10681 accaggcttc caccgccagg gtgacctcca tcgggctggc atggcgattg gtgtccacga
    10741 ggtcgtcaat ctgccggcac agggcgtaaa tggcatagat ggccgggcgc ttgtgcctgg
    10801 gaagcgtctg ggtgcagaag taaaagctct tggcgtgggt gcgcgtcacc tcacgacagt
    10861 aagcgtaggc ggcagcgacg gcggccgggt ccggcgtctg aagccttacc tgcccggcaa
    10921 aggggtcaag tgccgcaacg ctgccaacat tggttctcat gctctggttg cgtggacgga
    10981 atctgcatca gcgccattcg ggttgggaca accgcaacac gtcactgaaa acgtacccga
    11041 ctatggtata gacttcatac cagcgtcaac accggccggt atctgccagg gcccacctgg
    11101 cggcggacgg tccggaggtg tggagctgac ccgaacacgc ccgcctttac ccgaaaccac
    11161 catgcttgag gagttgagaa aatcacctgt gccgtcctcg gacgccgcgg ccacctcccc
    11221 cctgctgcaa acgctgctga accatgtgca actcctcgac ccggtcacct ggctcggtcc
    11281 ctggcagtgc ttctgctgtg gggtgctggc cacagggttg cgcctgtcag acctgacgct
    11341 gctggatggc gtcaaattct ttctcgcctg cggactcatc ggtccgctgc tgaccggctt
    11401 cagccagtcc atcaatgact atttcgaccg ccatctcgac gccatcaatg acccggagcg
    11461 tcccattcca tcgggacgga tttccctttc ggcggcccgc gccaacttca ccctgacggg
    11521 ccttctggcg ctgggcaaca tgtccctgct ctatgtcatc accggcagtc tgctgatcct
    11581 gattctgggg attgccgggc tgtttctggc ctatgcctac agcgcgccgg ggttccggct
    11641 gaaggaaaac ggctggctgg gaacgacttc cgtcggcatt ggatactgtc tggtgccctg
    11701 gctgctggcg gcgcatctgt tttcgcggga gccaggcttt ccatcgtttc acctggcgtt
    11761 gggggtggtc aatgccctgg tggccatggg gctcatcacc atgaacgact tcaaatccat
    11821 cgagggggac cgcaaaaaca acctcagaac gctcccggtg ctgtatggcg agcgtggggc
    11881 catgctcatt gcctttgccg aaatcaacct ggcgcaggtc atctttgtca tcacctgttt
    11941 tttctttggc tatgtcacca tcggctggct cggcatggcc ttcttcgtgc cccagctcat
    12001 tcagcaggta cagctctacc gcgcccccca tgacagccgg ctgctggaga gtatcggccg
    12061 caatgccgcc gggcgatcac tcgtcagcca gagccagtcc ggcgcccatc cgggcttcat
    12121 ccggtttctc gtcggaagta acctgatcac ggtcacggcc ctgacggccg tgtccatcgt
    12181 ccatgggtac tggcgctaga ccatggtttc agcataggga aaggaaacgg acgccatgaa
    12241 aaacacggaa ccttccacgg cttcagacag caccaaccag accagcgaag cttcgctcgc
    12301 agccttccgg acgctttccc tgcccgagaa ggccctgacg attgcacagg cccaggcgac
    12361 gctgttttcc aacaccatcg tgcgggcgct gtccacggtc ctgcgtggca gccgccccag
    12421 tgccggctag ggcagccacc ggtcaggccc acttcagggc ggcatccagg tcgaagcgcg
    12481 gctcccagcc caactgcccg ctggccttcg agaggtcgct gacgtaacgg cgctggtcgt
    12541 ccggtggcgg ctccgtatcg gtcagatgca gcaccggggg ggtcccgcag acccggccga
    12601 tgcgctgcgc cagctcggcc agcgggaagg cataggcggg gccgccaccg atgttgaagg
    12661 tgtcatggcc aacggatgaa gcgacacagg cgcgcagcac gttcacgagt tccgccaccg
    12721 gaaggacatc ccggacctgc cggccctgcc agcgcagcgt caggggttgc ccgtggcgga
    12781 tggcgtgggc aaaacggctg accagtccgc cgggattgcc cggcgtcggc ggcgcaaaga
    12841 ccgtggaaag ccgcaggaca cagagccgga agccgcgccg ggcggcatag aaacgggcat
    12901 attcctcggc cagccacttc gaccaggcgt aggcgttctg cccgtgcagg gtcgtcgggc
    12961 agctttccgg cacggcggca tagtgatcgg catgcgcgcc atagacatcc ttggtggagg
    13021 ccagcagcag ggtgtgctgt tcggtaagcc gggcgcagag ccagcgggtg ccgtcactgt
    13081 tgacctcgaa gcaggccgcc gcctcttccg gggctttggc gacgtgggcc gccaggtgca
    13141 cgatgacgcg gtggtgggcc agagcatccg ccagggccgg cgtaaacagg cccagtccct
    13201 gccgccgccc ggccaccgtg gcgcccaggg ccgccgccac atggacgccc agatagcctg
    13261 tcccacccgt caccagccag tcctgcttca cgcggggtcc ccggtccggg ccgtctccat
    13321 ccctgacggc ggacgactgt ggcgcgggaa ctggacggtc acggtcgttc ctttccccgg
    13381 ctcactgaca atggacaccc ggcccccata ggccgtcacg acatcccgca cgagggtcag
    13441 gccgatgccc agaccgccgc ccttgaagtt ggtacgggag gtgctgtggt actgcgtgct
    13501 ggccacttca taaaacgact cgaaggccac cgcaacttca tgggtggcca tgccaatgcc
    13561 gtcgtcctca acctcgatgg tgaaatgctg ctcatcggag gtcagccgga cgctgatgtt
    13621 gccgtggtca ggggtgaact tgacggcgtt gaagagcaat tcccgcagaa cctgggtcac
    13681 gcgcagcgca tcgcccactg ccggcaggtg ttccggcccg gccagatgat actggtgctg
    13741 gcgatgcatg gcgtgaaccc tgatttcttc gagcgttgcc cgcaccagcg ccatgacatc
    13801 gaacggctgg ctgtcgatag gcaggtaatc gctggtggtt gtcatcagaa gggtgaggtt
    13861 ctggacgatg gtggtgaggt tcgagatggc cacctgcatg gcggtgcggg cttcccggac
    13921 atcatcgggc gagtcggcca tcacggccag cagatcacag tagccctgaa gaatggtcag
    13981 cggcccgcgc agttcatggc tggtcatgcg gaggaacttt tccttgagct ccgtcaggcg
    14041 ttgcagttcc cggttggcat gctgaagggc ggtgttctgc tggcgcagca tcacccgctc
    14101 aaagcacttc tcgatggcca ggtgcatctg cccgacctcg aagggcttgg ggatgaaatc
    14161 actggcgccc agtttcatgg cctcgacggc ttcctcgatg cgcccatagc cggtaatcac
    14221 cagcacctcg atggccgggt catgggcctt gaccagttcg acgacggcca accccccctg
    14281 gcgcggcatg cgcagatcag tgatgaccag gtggggacgg aaactggcca gcagcggcgc
    14341 cacctcactg ccatccgcag ccgtgcacac ctggcaactg ctgagaaaat cctggaagaa
    14401 aagccggatt tcagcctcgt catccacgac gagaacccgg cgtttcagcc caaccgaagg
    14461 ggtggcggtg gcgacaggtt cttccatcac atgcgctcct gcgtctgggg gtgaacaacc
    14521 ggctgcggag ggcgtgccag gttcaggatt tcgtgggcca gttcatcctt ggtcatcagc
    14581 ggaagggccc gggtttcacc ggtggccaga acaaaggtgg cccggttggt gtcggtgtca
    14641 aacccggcgc cggcctcggt gacatcgttg aacaccagaa ggtcagcgcc tttgcggcgg
    14701 agcttttcca gggcggcctc ccgcgaccag ccggtttcgg cggcaaagcc gacgacgaag
    14761 cgggacccct tccgcgcgcc gaccgcggcg aggatgtctt cggtcggctc gaggtcgagc
    14821 tggcgcagcg gggactgggt ctttttcagc ttttcgaccg ccacctgccg cggacggtag
    14881 tcacagacgg cggcggcctt gatgaccagc gtcgccgccg gcagataccg cagcacggcg
    14941 tcatacatct cgcgggtgga gcggacggca atggtttcga ccccctccgg cggggacagc
    15001 cgcgtcggcc cactgatgag cgtgacggtg gcaccgcgcg catgtgcggc ccgcgccacc
    15061 gcgtagccca ttttccctga agaccggttc gtcaggtagc ggaccggatc aatgtcctcg
    15121 atggttggtc ccgccgtgac cagaacgtgg ttgccggtca ggtcacgggg ggttgtttcc
    15181 tgcgccgcca gcgatgtcca caccgtcccg acgatgccgg cagggtcggc caggcgccca
    15241 tccccgacca taccacaggc cagaaagccg gcctccggct cgatgatccg gacgccacgc
    15301 gcccgcaacc gggccaggtt ttcctgggtg gccggatgcc gccacatctc cacgttcatg
    15361 gccggcgcca caaatgtcgg gcaggtcgcc gccagataga cggtcgaaag aaaatcatcg
    15421 gcgataccgt gggccagttt ggcgaggcag ttggccgttg ccggggcaat caccagggcg
    15481 tcggtgcgct gggccagcgc gatgtgggca atttcggtat cgtcgtcgcg tccccagtgc
    15541 gacgtataca ccggctttcc ggaaagcgcc tgaaaggtca gcggctggat gaagcgcgtc
    15601 gcggactcgg tcatgacgac ctcgacggtg gcgccaagct gttgcaggcc acgcaaaacc
    15661 agaatcgctt tgtaggcgcc gatacatccg gtgacgccca gagtgatgtg cttggtcatg
    15721 ggaaggtccg cttgcttccc ggcgcatcca cccacagaaa aaccatcgca tgatggccgg
    15781 gcttggtttg tcaagaggat aacgctatcg tagcacagaa ggcatttcca gcgtcaccgg
    15841 gcagaagtct gcctccccgt gaaaggttac cgaccatgtc cactgaaagc agtgaaacca
    15901 ggttttcccc tctctccaag gaatttctcc acgtggtgga agttgcggcc atcgccgcgg
    15961 cgcgcaccat gggatttggc caaagaaagc agtccgaccg cgccgccgtc gaggccatgc
    16021 gggaggccat gcgtacggtg cgcatgaacg ggcggattgt gattggcgaa ggcgagcgtg
    16081 acaaagcccc gatgctctac atcggcgagc gcgtcggcgc cggggcggaa catcccgacg
    16141 acgatgagcg ctttccggcg gtggatattg ccgttgaccc gctcgaagga acgaatctct
    16201 gcgccacggg cgcggccaat gccattgccg ttctggcggc ggccgagcgg ggcggactgc
    16261 tccatgcccc cgacatgtac atgaacaagc tcgtcgttgg gccggccgcc aaaggacagc
    16321 tcgacattga cgcgccggtg gccgaaaacc tcaggattct ctcggcctgc ctgcggcggg
    16381 cggtcaccga tctcgtcgtc tcggtactcg accgtccgcg ccacgccaag ctcattgccg
    16441 acctccggga agccggggcc cggattcagc tcatttcgga tggcgacctc tcggccggca
    16501 tcagcgccgc cgtgggtggt tccggcgtcc atgccgtcat gggcattggc ggggccccgg
    16561 agggcgtgct gaccgccgca gccatgaaat gcctcaacgg tgaaatccag gcgcgcttcg
    16621 tgctgaagga ccagctccac gccgaagacc acaccaaagt caccgaagac agtgaaaccc
    16681 tcgcccgcat gcaggccatg gggatcgcgg acccggcgcg tgtctatcgg acggatgatc
    16741 tggcgcccgg aaagcacatc atctttgcca tgaccggcgt caccaacggc aatgtgctgc
    16801 gtggggtacg cttttttggc gcgggcaaac ggacggcatc gctgctgatg acgacctgcc
    16861 cgcataccgt gcggctggtg gatacggttc acgtcgaagg cggccccgat accgtcatcc
    16921 ggctgtgaag cgtccgcccc cggatgggca gtaccccgga tcggcagtac tccgtgaagg
    16981 tatggcgtca acggcgctgt ccgtcctata ctggcgcctc atcgaggcgt tcgccttcgt
    17041 cccaggctga ttgatggcgt ggctggtggc cggttcatcc ggttcacagg cattgggttt
    17101 tggtgttggt gtggctgacc gggttggggt caggctgacg tgcagccgga ttcccggcgt
    17161 tccgggcttg tatccggggg agacgtgcat gcgacatctg tttcgtggtt tcttcgcagg
    17221 ctggttgtgc ctggccctgg gtgtcaccct ggcacaggcc actgaacgtt ccgaaggatg
    17281 tgcggtggca ggggtggtga ccgatcaccg gggcagcccc attgcccatg ccatcgtttc
    17341 cattttccgg gacggggatg agaaggaagt cctggtgacg gcttccagtg accgcagcgg
    17401 ccggttctcg ctggcccggc tcacgcccgg cgtctatcgg ctgctggcgg cggcgcgtgg
    17461 tttccagacg ctgatcagtg agcccacggc gttggcgccg ggacaaacct cccagatgcg
    17521 cctgaccctg cgcccggcgc cggatgccag ggcgacgggg gtcaatccgg tgaagtatca
    17581 gaaccggcgc aaccgtggca tcttcaacgc cacggcttcc gaaacgccgg acgccggacg
    17641 gccgggcgcc cccctctggc aggggacggc gctgattggc tcgaccgggt acgacagcca
    17701 ggtgacggct gaagtcacac cggggatgga tgtgggcgct tacctgcgcc gtgactggga
    17761 gggccagtcc gtcaccatcg ggggggcgct gcgctacagc accggacagc accgcggacg
    17821 catccgctgg cagaccgacc aagtgacagc cgacccgatc atgtcatccc ccatgtcatc
    17881 cccggccgca ccagtgccgg gcggcccgtt tttccgccat gaccttcagg cggccgatgc
    17941 ctggcagatc accgaccggc tccaggtgct ctatggcttt gattacctcc gggcgggacg
    18001 cagccatgag gatgtctggc ggccacgcct ggccgcccac tggagtccct gcccggccgt
    18061 acaggtgcat acggcgctga catccgatgg acaagccttt ccggcctggg tggacccgga
    18121 acggccgctg ctgaccgacg acttccccac gccgccggcg cgtctggcgc tggtggatga
    18181 acgcccggtg ctggcgcgca acctgcgggt tgaggccggg gttgcctggc agatggatgc
    18241 ccggacaacg gtcaaagtct atgcctatca ggactggctg gacggccatc ccctcgccat
    18301 ggaagggcat gtcatgtcgc gcctggaggg acgcgcccag gggacagcca tcatcctcac
    18361 ccgccgcctg cgtccgcgcc tggcagtgac aacgggctat gcggccggcc ggacggcaac
    18421 gcggccggag gacgcagggc ttgcggcgtc aacctggctg cccggcacct accatgtcct
    18481 taccgtcgtg gctgaaaccg tcttccccgg cccggaaacc cagattcagg tgggctaccg
    18541 cagtgcctgg ggccatcccg ttcatgccat tgaccccttt accggccggc tgcccttcac
    18601 cgatgccgga ctgaacttca gaatcattca ggccctgccg ggctggatgt tcctgcccgg
    18661 gcggtgggaa gccgtcatcg agggccgcaa tctggatgag cggcgcagcg aagtcaccgg
    18721 actgggcgcg gcttttggct ttccccaccg gcggaccgtg cgtggcgggc tccgcttccg
    18781 cttctgaagt ctatggcctc ccgttcctac ccaacctggt gcgtggttgt ggtcagtctg
    18841 ggcatcaccc tgcttggact tctgaacctc atggaccgcg ccgtgcagcc cccaccggcc
    18901 gatgacgggg tgcggtggcg cgccacgccc caggggttga tggccgaaag tgtccgggcc
    18961 ggcagctcgg ccgagcgcgc cggcgtcatc cggggggatg tgctccgggc gatcctcgtc
    19021 gagacgaacc cccaggaccc gccggaaccg ctggccgtca ccaaggaatg gcacatccag
    19081 tactacctgg acgaatacgt ccatgtcggc ggcaacgcca cctacctcgt cgaacgctac
    19141 aacccccgcg gcctcagtct cggtctctgg caggccgagt tgcgccagct tgacccgcag
    19201 cccagccgct tctggtttga ggtctatgcc gcgtttgtcg gcgcgctgta cctgctcatc
    19261 ggcctggtgg tcttcaccaa gcacgaacat gtgtcccagg cgctgcactt ttttgccatc
    19321 tgcgccctgt cgttcattta cctcgtctgg aacaccagcg gggcgttgac gacttttgac
    19381 accttcattc tctgggccga ccgggtctcc ctgattgtcc tgtgcccgac cttcctccac
    19441 ttctgcgcca cctttcccct gcgcagcgcc tggcttgaac ggcgccggcg cctcatctgg
    19501 ctgatgtacg gcccggccgt cgtcctggcg ctgttcgaga cgcttcacct gtttctgggg
    19561 cgctacagcg cctggctgct cgacctgcgc ccgacgctcg accagctcac cctcatccac
    19621 tttgccgtgg cctttgccgc ggccctcagt gtcgtcacgg tgacgttctt ccagaccgaa
    19681 accccgctgc tcaagcagca gatgaagtgg atggtggtgg ggctgacgct gggcattgtc
    19741 ccgtggctgg ctttttacgg ggcgccggtc gtggcgggcg tggagccgac gccggtcatg
    19801 gaggccctgg cgctgggtcc cacggtcttc attccacttg ccttcggcta cgccatcgtc
    19861 cgctaccgcc tcatggatgt ggatgtcatc gtgcggcgca gcctgaccta tgcgctggcg
    19921 acctttggcg tggtcatgat cttcatgctc ggtgtggtca agatggccga ctggatacgg
    19981 gagacctatc cggccgttcc acccgtgacc acgaccttcc tgcaggtggt ggtgctctcc
    20041 ggcggcgcca tgctctatgc acccttcaaa aactggcttc aggaacggat tgaccggatt
    20101 ttttacggcg cccgctatga cacccgcctc ggactggcgg acttcgggcg cgccatggcc
    20161 acgacgaccg cccttcccga actgctttca gccattgcgc ggaagctttc cgatgccgtg
    20221 tccgtgacgg acctggcgat ctttctccct gacaccacca cgccgccgga agatgcagcc
    20281 aggggcacgc cacacctccg gccggtcttt gccagcgggt tgacgggtcc ggtgatgccg
    20341 tcccatatcg aacagaacat cctccaggcc ggcccccgtg gctatctcgt ggatgaagcc
    20401 gggctggccg agggcgacct ggcctattac tttccgtgcg tggcgcgggg ccggctggtg
    20461 gccgtcattg cgctgggcaa gaccgtcgag cgcacccttc tgacctcgga agacacggaa
    20521 ctgctgcgcg gactggcgcc ctacatggcc gtggccattg aaaacagcct tttttacgag
    20581 cgcgagcggg cgcgggttga ggaactggcc cggctcaagg aattcaacga aaacatcatc
    20641 gagtccatca acgtcggcat cgtcgtcatt gactgccggg ggcaactgac gacctggaac
    20701 agcaccttcg agaaactgtt tgccctgccg ccaccgccgc cggaagggtg ggcgctggag
    20761 acgctgtttg acccggacct cctgtgcatg atgcgcgggg tcatcggcgg caatgcgggc
    20821 tggcagatta cggacacccg cacgatttat cgctgccgca cccagggacg cgacggacaa
    20881 tccctcgtgc tcaacatcac gctcctgccg ctccagaccc gcgccctgac ggacggtggg
    20941 gccctgattt gcttcgagga
//
